Modulation of AMPA receptor unitary conductance by synaptic activity

Article Abstract:

The induction of long-term potentiation in the CA1 region of the hippocampus is often linked with a rise in single-channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropiante (AMPA) receptors. Synaptic activity can rapidly change elementary channel properties. The rise in the single-channel conductance of AMPA receptors may be the result of a rise in the relative time that AMPA receptors spend in the high-conductance states. It has been demonstrated that the initial state of the AMPA receptors may determine changes in synaptic efficiency.

Hippocampus (Brain), Neural receptors

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Long-term motor cortex plasticity induced by an electronic neural implant

Article Abstract:

A study proposes that the efficacy of neuronal connections is strengthened when there is a persistent causal relationship between presynaptic and postsynaptic activity. It is shown that stable reorganization of motor output can be induced by an artificial connection between two sites in the motor cortex of freely behaving primates.

Analysis, Adaptation (Physiology), Physiological adaptation, Motor ability, Motor skills

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Presynaptic induction of heterosynaptic associative plasticity in the mammalian brian

Article Abstract:

Presynaptic and postsynaptic activity are the determining factors involved in the induction of associative synaptic plasticity in the mammalian central nervous system. A new mechanism underlying the induction of associative long-term potentiation (LTP) in the lateral amygdala (LA) is presented.

Central nervous system, Mammals

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