Death of a chaperone

Article Abstract:

A bacterial toxin SubAB selectively attacks BiP protein that is vital to the correct functioning of the endoplasmic reticulum. BiP at the surface of human prostate cancer cells enhances the spread of the cancer to other regions of the body, suggesting that this protein could be a cell-surface target for therapeutic use of the A subunit.

Italy, Health aspects, Genetic aspects, Prostate cancer, Endoplasmic reticulum, Molecular chaperones

---

Dangerous liaisons on neurons

Article Abstract:

The different mechanisms by which botulinum neurotoxin (BoNT)/B, a toxin that causes human botulism, recognizes the surface of neuron junctions are discussed. BoNTs are found to be powerful tools and can be used as therapeutics for treating certain nervous-system diseases.

Care and treatment, Neurons, Botulinum toxin, Botulinum toxins, Nervous system diseases

---

Similar abstracts:

• Abstracts: Ageing and the mystery at Arles. The future of ageing. Oxidants, oxidative stress and the biology of ageing
• Abstracts: Reagents for the site-specific cleavage of megabase DNA. DNA correlations. Long-range correlations in DNA
• Abstracts: Peptides bound to MHC. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
• Abstracts: Pulsar glitches as probes of neutron star interiors. A brief history of pulsar time
• Abstracts: Rumblings grow about Parkfield in wake of first earthquake prediction. Chemistry prize

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.