Adaptive response of Schizosaccharomyces pombe to hydrogen peroxide and menadione

Article Abstract:

Pretreatment of Schizosaccharomyces pombe cells to sublethal concentrations of H2O2 and menadione (MD) induces resistance to oxidative stresses. The resistance is due to the induction of antioxidant enzymes. MD-induced resistance is greater than H2O2-induced resistance probably because MD increases the production of wider variety of enzymes. The GSH/GSSG ratio of the cells also increases. Cells in a stationary phase are more resistant than those in an exponential phase due to higher levels of the antioxidant enzymes.

Cyanobacteria, Hydrogen peroxide

---

Enzyme evolution in Rhodobacter sphaeroides: selection of a mutant expressing a new galactitol dehydrogenase and biochemical characterization of the enzyme

Article Abstract:

A functional mutant of Rhodobacter (R.) sphaeroides Si4 that can grow on galactitol, produces large quantities of a galactitol dehydrogenase (GDH). The N-terminal amino-acid sequence of the GDH reveals that it is a new enzyme as it exhibits properties different from other polyol dehydrogenases. Characterization of the enzyme indicates that it is a tetramer and though specific for AND (super +), catalyzes the oxidation of many sugar alcohols diols and secondary alcohols.

Research, Observations, Microbial mutation, Alcohol dehydrogenase, Alcohol dehydrogenases, Polyols

---

NAD(P)H:menadione oxidoreductase of the amitochondriate eukayote Giardia lamblia: a simpler homologue of the vertebrate enzyme

Article Abstract:

Results show that purified recombinant NAD(P)H:menadione oxidoreductase exhibits typical oxidoreductase activities with NADPH serving as its electron donor. Data also indicate that the enzyme possesses high amino acid sequence similarity to its vertebrate homologues.

United States, Statistical Data Included, Oxidoreductases, Enzyme kinetics, Giardia, Giardia lamblia

Similar abstracts:

• Abstracts: Regulation of manganese peroxidase gene transcription by hydrogen peroxide, chemical stress, and molecular oxygen
• Abstracts: Overproduction of threonine by Saccharomyces cerevisiae mutants resistant to hydroxynorvaline. Redirection of the respiro-fermentative flux distribution in Saccharomyces cerevisiae by overexpression of the transcription factor hap4p
• Abstracts: Polyunsaturated fatty acid biosynthesis in Saccharomyces cerevisiae: expression of ethanol tolerance and the FAD2 gene from Arabidopsis thaliana
• Abstracts: Developmental regulation of SR protein phosphorylation and activity. Temporal and spatial regulation of Rho-type guanine-nucleotide exchange factors: the yeast perspective
• Abstracts: PAGE analysis of the heteroduplexes formed between PCR-amplified 16S rRNA genes: estimation of sequence similarity and rDNA complexity

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.