GMAP-210 recruits gamma-tubulin complexes to cis- Golgi membranes and is required for Golgi ribbon formation

Article Abstract:

GMAP-210, a cis-Golgi microtubule binding protein, recruits gamma-tubulin-containing complexes to Golgi membranes even in conditions where microtubule polymerization is prevented and independently of Golgi apparatus localization within the cell. The findings suggest that GMAP-210 displays microtubule anchoring and membrane fusion activities, thus contributing to the assembly and maintenance of the Golgi ribbon around the centrosome.

Golgi apparatus, Binding proteins

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Nanoscale organization of multiple GPI-anchored proteins in living cell membranes

Article Abstract:

The investigation of the size of the lipid-dependent organization of glycosyl-phosphophatidylinositol-anchored proteins (GPI-APs), in live cells is done using homo and hetero-FRET-based experiments along with theoretical modeling. An analysis of the statistical distribution of clusters is presented and the observation suggests a mechanism for the functional lipid-dependent clustering of GPI-APs.

Analysis, Lipids, Protein structure

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To kill but not be killed: A delicate balance

Article Abstract:

The mechanism underlying a biological safety net for the soil bacterium Bacillus subtilis is discussed. The bacterium protects itself from a toxic protein it secretes by upregulating an immunity protein, which it does by sequestering a transcriptional repressor at the plasma membrane.

Australia, Physiological aspects, Genetic aspects, Bacillus subtilis, Biological systems

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