Effect of sampling on topology predictions of protein-protein interaction networks

Article Abstract:

Four generated theoretical interaction networks of different topologies and partial sampling of these networks resulted in sub-networks with topological characteristics that were virtually indistinguishable from those of available yeast two-hybrid (Y2H)-derived partial interactome maps. Given the current limited coverage levels, the observed scale-free topology of existing interactome maps cannot be confidently extrapolated to complete interactions.

Analytical Laboratory Instrument Manufacturing, Analytical instruments, Ion Mass Spectroscopy, Usage, Proteins, Mass spectrometry, Hybridization, Vegetable, Hybrid plants

---

Drug-target network

Article Abstract:

Network biology is used to analyze drug targets as a part of cellular and disease networks and to quantify their interrelationships with disease-gene products. Drug targets are becoming more related to disease-gene products because of an increased understanding of the genetic basis of disease.

Drug targeting, Genomics, Report

---

Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans

Article Abstract:

The 'in vivo' spatiotemporal analysis of the genome of Caenorhabditis elegans integrates the data sets with and worm profiling, chronogram generation, clustering, and cluster enrichments. The results help to predict the protein interactions.

Analysis, Genetic aspects, Caenorhabditis elegans, Bacterial proteins, Protein-protein interactions

Similar abstracts:

• Abstracts: Gaining confidence in high-throughput protein interaction networks . Closing the circle of osmoregulation
• Abstracts: Computational prediction of proteotypic peptides for quantitative proteomics. Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor
• Abstracts: Carafano would place anti-terror bets on 6 technologies. Security applications driving strong growth in Biometrics
• Abstracts: When a long shot is worth a shot. The protection racket. A rollercoaster ride
• Abstracts: Summary recommendations for standardization and reporting of metabolic analyses. The challenges of modeling mammalian biocomplexity

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.