Computational modeling approaches to structure-functional analysis of G protein-coupled receptors

Article Abstract:

The results of computational experiments attempted in past are reviewed to gain insights into different aspects of family A G protein-coupled receptors (GPCR) function. GPCRs constitute the largest superfamily of membrane proteins known to date and regulate any aspect of cell activity by transmitting extracellular signals inside the cell.

United States, G proteins, Rhodopsin

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Systematic genome reduction: theoretical and experimental approaches

Article Abstract:

The theoretical and experimental progress on genome minimizations for three prokaryotic organisms, Escherichia coli and Bacillus subtilis model systems with biotechnological and industrial interests and Corynebacterium glutamicum for amino acid fermentation industry are reviewed.

Analysis, Genetic aspects, Prokaryotes, Polymerase chain reaction, Gene expression, DNA synthesis

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The nose as a stereochemist. Enantiomers and odour

Article Abstract:

The enantioselectivity on the human nose with respect to smell is discussed. The role of chirality in insect pheromones and a wider view of the perception of enantiomers are described.

Pennsylvania, Chirality, Enantiomers, Atomic properties

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