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Enoxaparin vs. unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy

Article Abstract:

Enoxaparin has shown better results over unfractionated heparin in low-to-moderate risk patients with non-ST-segment elevation acute coronary syndromes (ACS) and tests were conducted to compare the outcomes of patients treated with either of the drugs. Enoxaparin was not found to be superior to unfractionated heparin, but it is safe and an effective alternative.

Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004

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Safety and efficacy of enoxaparin vs. unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes who receive tirofiban and aspirin

Article Abstract:

Tests were conducted to check the efficacy of the combination of enoxaparin and tirofiban in comparison with unfractionated heparin and tirofiban in patients with non-ST-elevation acute coronary syndromes (ACS). It was found that in patients receiving tirofiban and aspirin enoxaparin is a good alternative when compared to unfractionated heparin.

Author: Califf, Robert M., White, Harvey D., Hasselblad, Vic, Braunwald, Eugene, DiBattiste, Peter M., Snapinn, Steven M., Pfeffer, Marc A., Ardissino, Diego, Blazing, Michael A., Ramsey, Karen E., Lemos, James A. de, Gardner, Laura H., Palmisano, Joanne, Fox, Keith A. A., Bilheimer, David W., Verheugt, Freek W. A., Lewis, Eldrin F.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004

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Fractionating heparins and their clinical trial data-something for everyone

Article Abstract:

Heparin is known to reduce ischemic occurrences beyond that of aspirin in acute coronary setting and unfractionated heparin is known to have several limitations and inability to inhibit clot-bound thrombin. Trials show that enoxaparin is a good alternative to unfractionated heparin in regular acute coronary syndrome (ACS) treatment.

Author: Moliterno, David J., Das, Pranab
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
Science & research, Research

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Subjects list: Care and treatment, United States, Coronary heart disease, Comparative analysis, Dosage and administration, Heparin, Enoxaparin
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