Abstracts - faqs.org

Abstracts

Health

Search abstracts:
Abstracts » Health

Histologic Improvement of Fibrosis in Patients with Hepatitis C Who Have Sustained Response to Interferon Therapy

Article Abstract:

Interferon therapy may cause liver fibrosis to regress in patients with hepatitis C. Researchers took liver biopsies three years apart in 593 patients with hepatitis C, of whom 487 began taking interferon within six months of the first biopsy. Of the patients taking interferon, 183 had a response indicated by a suppression of the virus. In these 183 patients, liver inflammation and fibrosis regressed in 89%. Patients who did not respond to interferon and those never treated had no changes in their liver biopsy.

Author: Shiratori, Yasushi, Imazeki, Fumio, Moriyama, Mitsuhiko, Yano, Michitami, Arakawa, Yasuyuki, Yokosuka, Osamu, Kuroki, Tetsuo, Nishiguchi, Shuhei, Sata, Michio, Yamada, Gotarou, Fujiyama, Shigetoshi, Yoshida, Haruhiko, Omata, Masao
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2000
Drug therapy, Liver

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Increased nitric oxide in the exhaled air of patients with decompensated liver cirrhosis

Article Abstract:

Patients with liver cirrhosis may develop heart disorders due to increased levels of nitric oxide in their exhaled air. Patients with liver cirrhosis frequently have heart disorders relating to low blood pressure. Researchers measured the exhaled nitric oxide output and heart output of 50 patients with liver cirrhosis, 6 patients with long-term hepatitis, and 15 healthy volunteers. They divided the patients with liver cirrhosis into 3 groups according to the severity of the disease. Patients with the most advanced stage of liver cirrhosis had higher levels of both nitric oxide output and heart output than the healthy people. There was no difference in nitric oxide output and heart output in patients with less severe liver cirrhosis and those with hepatitis compared to the healthy people.

Author: Shiratori, Yasushi, Omata, Masao, Matsumoto, Akihiro, Ogura, Keiji, Hirata, Yasunobu, Kakoki, Masao, Watanabe, Fumiyoshi, Takenaka, Katsu, Momomura, Shin-ichi
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1995
Measurement, Physiological aspects, Nitric oxide, Liver cirrhosis

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Interferon Therapy Reduces the Risk for Hepatocellular Carcinoma: National Surveillance Program of Cirrhotic and Noncirrhotic Patients with Chronic Hepatitis C in Japan

Article Abstract:

Interferon therapy can significantly reduce the risk of liver cancer, especially among people who test positive for viral presence or biochemical risk factors. Of 2,890 patients with chronic hepatitis C, 2,400 were given interferon therapy and 490 were not treated. Liver cancer developed in 89 of the 2,400 on interferon and in 59 of the 490. When statistics were adjusted for variable factors, the interferon group showed about half the risk of the others.

Author: Shiratori, Yasushi, Moriyama, Mitsuhiko, Yano, Michitami, Arakawa, Yasuyuki, Yokosuka, Osamu, Kuroki, Tetsuo, Nishiguchi, Shuhei, Sata, Michio, Fujiyama, Shigetoshi, Yoshida, Haruhiko, Omata, Masao, Ide, Tatsuya, Inoue, Osami, Tanaka, Motohiko, Imazake, Fumio, Kinoyama, Shingo, Yamada, Gotaro
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1999
Statistical Data Included, Risk factors, Liver cancer

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Health aspects, Hepatitis C, Interferon
Similar abstracts:
  • Abstracts: Effects of Exercise Training on Left Ventricular Function and Peripheral Resistance in Patients With Chronic Heart Failure: A Randomized Trial
  • Abstracts: Primary hepatocellular carcinoma after orthotopic liver transplantation for chronic hepatitis B infection. Fatal Hyperammonemia after Orthotopic Lung Transplantation
  • Abstracts: Associations of serum lipids with metabolic control and diet in young subjects with insulin-dependent diabetes mellitus in Finland
  • Abstracts: Prevalence of Chlamydia trachomatis in urine of male patients with ankylosing spondylitis is not increased. Predictors of functional status in patients with early rheumatoid arthritis
  • Abstracts: Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.