Mifepristone versus vaginally administered misoprostol for cervical priming before first-trimester termination of pregnancy: a randomized, controlled study

Article Abstract:

Mifepristone can soften the cervix, making surgical abortion easier. This as the conclusion of a study of 90 women who were given oral mifepristone 24 to 48 hours before surgery or vaginal misoprostol 2 to 4 hours before surgery.

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Medical abortion at 64 to 91 days of gestation: a review of 483 consecutive cases

Article Abstract:

A medical abortion can be safely done in the late first trimester, according to a study of 483 women whose pregnancy was between 64 and 91 days. Ninety-five percent of the women had a successful abortion when they took mifepristone followed by misoprostol 36 to 48 hours later. The average time to abortion was 5.5 hours.

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A randomized controlled comparison of sublingual and vaginal administration of misoprostol for cervical priming before first-trimester surgical abortion

Article Abstract:

A study was conducted to compare the effectiveness of the sublingual and vaginal administration of misoprostol for cervical priming before surgical termination of pregnancy. In a randomized controlled trial, 74 primigravid women who were undergoing surgical abortion were assigned randomly to receive misoprostol sublingually or vaginally and it was found that despite higher incidence of side-effects, the sublingual administration proved more effective and acceptable.

Research and Development in the Physical, Engineering, and Life Sciences, Science & research, Research and Testing Services, Gynecological R&D, Research, Gynecological research, Obstetrical surgery

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