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Risk factors for mother-to-child transmission of human immunodeficiency virus-1 infection

Article Abstract:

Risk factors associated with HIV transmission from mother to child among an African population were placental inflammation, lower maternal CD4 cell counts, and female fetus. A group of 94 infants exposed to HIV in the womb were tested at 6 weeks and 3 months for the presence of proviral HIV-1. All infants were breastfed, a possible confounding factor for determining intrauterine transmission rates because HIV can be transmitted in breast milk. Thirty-one percent of infants tested positive. Placental inflammation, declining CD4 count, and female gender associated with HIV transmission. Disruption of the maternal-fetal barrier in the placenta would logically facilitate transmission as would impaired maternal immune status. The association with female fetus has been seen in an Italian and a Dutch study, but it is difficult to explain.

Author: Bwayo, Job, Piot, Peter, Temmerman, Marleen, Fransen, Katrien, Nyong'o, Aggrey O., Coppens, Mieke
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
Women, Risk factors, HIV infections, HIV infection in children, Pediatric HIV infections, Disease transmission, HIV infection in women

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Antimicrobial prophylaxis in pregnancy: a randomized, placebo-controlled trial with cefetamet-pivoxil in pregnant women with a poor obstetric history

Article Abstract:

Pregnant women with a history of delivering stillbirths or low birth weight infants appear to benefit from an antibiotic containing cefetamet-pivoxil given once in the last trimester. Three hundred twenty at-risk pregnant women were given either cefetamet-pivoxil or placebo between 28 and 32 weeks of pregnancy. Women given the antibiotic delivered fewer stillbirths, higher birth weight infants, and experienced fewer uterine and gonorrhea infections than those given placebo.

Author: Ndinya-Achola, Jackoniah O., Temmerman, Marleen, Nagelkerke, Nico J., Gichangi, Peter B., Ombete, John
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
Care and treatment, Usage, Antibiotics, Prevention, Pregnant women, Birth weight, Low, Low birth weight, Endometritis

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Culture-independent analysis of virginal microflora: The unrecognized association of Atopobium vaginae with bacterial vaginosis

Article Abstract:

Microorganisms like Gardnerella vaginalis are considered markers on grain stain or culture, although the pathogenesis of bacterial vaginosis remains elusive. Gram-positive atopobium vaginae are believed to be a predominant species in disturbed vaginal flora.

Author: Temmerman, Marleen, Verstraelen, Hans, Verhelst, Rita, Claeys, Geert, Vaneechoutte, Mario
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
United States, Science & research, Research, Causes of, Vaginosis, Anaerobic bacteria, Bacterial vaginosis, Gram-positive bacterial infections

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