Thrombopoietin

Article Abstract:

The discovery of thrombopoietin in 1994 raises the hope of a better treatment for thrombocytopenia. Thrombocytopenia is a drop in the number of blood platelets, which are crucial for blood clotting. Platelet transfusions are the main treatment, but they are expensive and not an ideal treatment. Thrombopoietin is a hormone that stimulates the production of blood platelets. Studies have shown that it can reverse thrombocytopenia and also raise platelet levels after chemotherapy and bone marrow transplantation.

Care and treatment, Physiological aspects, Blood platelets, Thrombocytopenia

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Lineage-specific hematopoietic growth factors

Article Abstract:

The mechanism and clinical applications of three hematopoietic growth factors related with erythropoietin, granulocyte colony-stimulating factor, and thrombopoietin are surveyed. The clinical use of hematopoietic growth factors has improved the care of patients with inadequate blood-cell production, but these agents are costly, require parenteral administration, and could occasionally induce untoward effects.

England, Comparative analysis, Cell proliferation, Granulocyte colony-stimulating factor, Thrombopoietin

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Do cancer cells express functional erythropoietin receptors?

Article Abstract:

The effect of erythropoietin on tumor-cell growth and survival is discussed due to the increasing concern regarding its use in patients with cancer.

Cancer patients, Cancer cells

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