Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism

Article Abstract:

A study was conducted to determine the crystal structure of a proteolytic fragment of Saccharomyces cerevisiae Sro7, spanning residues 61-962, at 2.4 Angstrom resolution. The results suggest that Sro7 acts as an allosteric regulator of exocytosis through interactions with factors that control the tail.

Cell receptors, Polarity (Biology)

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Crystal structure of the human [[beta].sub.2] adrenergic G-protein-coupled receptor

Article Abstract:

The crystal structure of the human [[beta].sub.2] adrenergic G-protein-coupled receptor, [[beta]AR] is discussed which was crystallized in a lipid environment when bound to an inverse agonist and in complex with a Fab that binds to the third intracellular loop.

G proteins, Crystallization, Neurotransmitters, Adrenergic agents

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How to build a cell junction

Article Abstract:

Adhesive junctions are structures, which permit cells to stick to each other and attach to the extracellular matrix. These adhesive junctions enable the development and organization of tissues.

United States, Cell adhesion

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