Protein control of redox potentials of iron-sulfur proteins

Article Abstract:

The modelling of variations in redox potentials of iron-sulfur proteins with changes in the protein environment involves accounting for Coloumbic interactions between the charged cluster and the protein to allow polarizability of the protein. The process should also consider the interactions of both the cluster and the protein with the aqueous medium. The use of Protein Dipoles Langevin Dipoles (PDLD) favours the incorporation of bulk water and intercalated water. Molecular dynamic averaging enhances the accuracy of the PDLD calculations.

Models, Metalloproteins, Oxidation-reduction reaction, Oxidation-reduction reactions

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Peroral route: an opportunity for protein and peptide drug delivery

Article Abstract:

This article examines recent understanding about the peroral route for delivery of proteins and peptide drugs with particular reference to bioavailability of peroral drugs. Research discusses physical barriers to absorption, enzyme barriers and inhibitors, dosage, and colonic drug delivery systems.

India, Usage, Evaluation, Therapeutics, Drug delivery systems, Dosage and administration, Liposomes, Oral medication, Oral drugs

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Regulatory mechanism for receptor protein tyrosine phosphatases

Article Abstract:

Research has been conducted on the protein tyrosine phosphatases. The regulatory mechanisms for the receptor-like protein tyrosine phosphatases are discussed.

United States, Statistical Data Included, Physiological aspects, Proteins, Cell receptors, Phosphatases, Microbiological research, Tyrosine

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