Nature Medicine 2004 - Abstracts
| Nature Medicine 2004 | |||||
| Title | Subject | Authors | |||
|---|---|---|---|---|---|
| 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone. | Health | David K. Grandy, James R. Bunzow, Daniel Hatton, Thomas S. Scanlan, Katherine L. Suchland, Matthew E. Hart, Grazia Chiellini, Yong Huang, Riccardo Zucchi, Emil T. Lin, Simonetta Ronca-Testoni, Dane A. Crossley, Sabina Frascarelli, Paul J. Kruzich | |||
| 4-1BB-mediated immunotherapy of rheumatoid arthritis. | Health | Su k. Seo, Young H. Kim, Hye Y. Park, Beom K. Choi, Byoung S. Kwon, Jae H. Choi, Woo J. Kang, Jae H. Suh, Vinay S. Dass | |||
| Aberrant cannabinoid signaling impairs oviductal transport of embryos. | Health | Sudhansu K. Dey, Lawrence J. Marnett, Dingzhi Wang, Haibin Wang, Philip J. Kinsley, Sanjoy K. Das, Yong Guo, Raymond N. DuBois | |||
| A CD4+ T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease. | Health | Brian M. Greenwood, Simone Everaere, William H.H. Reece, Paul Milligan, Katherine R. Watkins, Ali Alloueche, Keith P.W.J. McAdam, Margaret Pinder, Philip K. Gothard, Kalifa Bojang, Tom Doherty, Magdalena Plebanski, Peter Akinwunmi, Gerald Voss, Nadia Tornieporth, Kent E. Kester, Cohen, Joe; Hill, Adrian V.S. | |||
| A COG in the sugar machine.(conserved oligomeric Golgi ) | Health | Thorsten Marquardt | |||
| Acting alone. | Health | Kristine Novak | |||
| Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. | Health | Rajnish A. Gupta, Dingzhi Wang, Sharada Katkuri, Haibin Wang, Sudhansu Dey K. | |||
| A decade of discovery in cardiac biology. | Health | Eric N. Olson | |||
| Adiponectin acts in the brain to decrease body weight. | Health | Hiralben R. Patel, Rexford S. Ahima, Anders H. Berg, Philipp E. Scherer, Yong Qi, Nobuhiko Takahashi, Stanly M. Hileman, Utpal B. Pajvani | |||
| Adiponectin-mediated modulation of hypertrophic signals in the heart. | Health | Kaori Sato, Wilson S. Colucci, Ichiro Shiojima, Kenneth Walsh, David R. Pimentel, Rei Shibata, Noriyuki Ouchi, Masahiro Ito, Shinji Kihara Kihara, Masahiro Kumada, Stephan Schiekofer, Ohashi Koji, Fnahashi Tohru | |||
| Advances in detecting and responding to threats from bioterrorism and emerging infectious disease. | Health | James M. Hughes, Lisa D. Rotz | |||
| Advances in the early detection of Alzheimer's disease. | Health | Peter J. Nestor, Philips Scheltens, John R. Hodges | |||
| A lab of her own. | Health | Gunjan Sinha, Charlotte Schubert | |||
| Alchemy in the liver: fact or fusion? | Health | George Q. Daley | |||
| A MARCKS - related peptide blocks mucus hypersecretion in a mouse model of asthma. | Health | Monique Singer, B. Boris Vargaftig, Achim D. Gruber, Yeuhua Li, Kenneth B. Adler, Linda D. Martin, Joungjoa Park | |||
| AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis.(acute myeloid leukemia) | Health | Motoshi Ichikawa, Takashi Asai, Toshiki Saito, Sachiko Seo | |||
| AML-1 steps up to the platelets.(Acute Myeloid Leukamia-1) | Health | Brenda J. Irvin, Scott W. Hiebert | |||
| An attack on all fronts. | Health | Pedro Alonso, Klausner Richard | |||
| Androgen receptor outwits prostate cancer drugs. | Health | John T. Isaacs, William B. Isaacs | |||
| An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus. | Health | Antonio Lanzavecchia, Rino Rappuoli, Brian R. Murphy, Larissa Kolesnikova, Kanta Subbarao, Elisabetta Traggiai, Stephen Becker, Yasushi Uematsu, Maria Rita Gismondo | |||
| Aneurysms: Leukotrienes weaken aorta from the outside. | Health | Wulf Palinski | |||
| A new algorithm weighs in. | Health | Natalie Wilson | |||
| A new cell-permeable peptide allows successful allogeneric islet transplantation in mice. | Health | Hirofumi Noguchi, Masayuki Matsushita, Teru Okitsu, Akiyoshi Moriwaki, Kazuhito Tomizawa | |||
| A new role for Nogo as a regulator of vascular remodeling. | Health | Stephen M. Strittmatter, David Fulton, William C. Sessa, Lisette Acevedo, Jun Yu, Hediye Erdjument-Bromage, Paul Tempst, Ji-Eun Kim, Robert Qing Miao | |||
| An innately interesting decade of research in immunology. | Health | Ronald N. Germain | |||
| Antibacterial resistance worldwide: Causes, challenges and responses. | Health | Bonnie Marshall, Stuart B. Levy | |||
| Antibody diversity: One enzyme to rule them all. | Health | Frederick W. Alt, Michel C. Nussenzweig | |||
| Antidepressant reputation falls to new lows. | Health | Erika Check | |||
| Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. | Health | Min-seon Kim, Joong-Yeol Park, Cherl Namkoong, Pil-Geum Jang, Je-won Ryu, Hai-Sun Song, Ji-Young Yun, Namgoongm Il-Seong, Joohun Ha, In-Sun Park, In-Kyu Lee, Benoit Viollet, Jang Hyun Youn | |||
| Antisickling effects of an endogenous human alpha-like globin. | Health | Zhenning He, J. Eric Russell | |||
| APCs size up antigens.(Antigen-presenting cells) | Health | Stephen P. Schoenberger, Keith S. Bahjat | |||
| Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides. | Health | Steven M. Paul, Milla Koistinaho, Suizhen Lin, Zin Wu, Michail Esterman, Deanna Koger, Jeffrey Hanson, Richard Higgs, Liu Feng, Seema Malkani, Kelly R. Bales | |||
| Arming the osteoclast. | Health | Roland Baron | |||
| A role for streptococcus pneumoniae in virus-associated pneumonia. | Health | Keith P. Klugman, Shabir A. Madhi | |||
| Ascorbic acid treatment corrects the phenotype of a mouse model of Charcot-Marie-Tooth disease. | Health | Edith Passage, Pauline Noack-Fraissignes, Josette Pizant, Andree Robaglia-Schlupp, Michel Fontes, Jean Chretien Norreel, Veronique Sanguedolce, Xavier Thirion, Jean Francois Pellissier | |||
| A transcriptional basis for physiology. | Health | Ronald Evans | |||
| A transgenic mouse model for monitoring endoplasmic reticulum stress. | Health | Takao Iwawaki, Ryoko Akai, Kenji Kohno, Masayuki Miura | |||
| Aurora kinases dawn as cancer drug targets. | Health | Edward A. Sausville | |||
| Autoimmune hypothyroidism: T cells caught in the act. | Health | Sandra M. McLachlan, Basil Rapoport | |||
| Autoimmunity is triggered by cPR-3 (105-201), a protein complementary to human autoantigen proteinase-3. | Health | Ronald J. Falk, William F. III Pendergraft, Gloria A. Preston, Ruchir R. Shah, Alexander Tropsha, Charles W. Carter Jr., J Charles Jennette | |||
| Back to the future: the 'old-fashioned' way to new medications for neurodegeneration. | Health | Peter T. Jr. Lansbury | |||
| Balancing muscle hypertrophy and atrophy. | Health | Eric P. Hoffman, Gustavo A. Nader | |||
| Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. | Health | Yue Wang, Weijia Kong, Jing Wei, Parveen Abidi, Meihong Lin, Satoru Inaba, Cong Li, Yanling Wang, Wang Zizheng, Shuyi Si, Huaining Pan, Shukui Wang, Jingdan Wu, Zhuorong Li, Jingwen Liu, Jian-Dong Jiang | |||
| Between hope and a hard place. | Health | Brian Greenwood | |||
| Biologists try to work out bugs in GM insect technology. | Health | Kendall Powell | |||
| Bioluminescent imaging of Cdk2 inhibition in vivo. | Health | William G. Kaelin Jr., Guo-Jun Zhang, Michal Safran, Wenyi Wei, Erik Sorensen, Peter Lassota, Shapiro. Geoffrey, Donna S. Neuberg, Nikolai Zhelev | |||
| Bone marrow-derived hematopoietic cells generate cariomyocytes at a low frequency through cell fusion, but not transdifferentiation. | Health | Jenes M. Nygren, Stefan Jovinge, Martin Breitbach, Oetter Sawen, Wilhelm Roll, Jurgen Hescheler, Jalal Taneera, Bernd K. Fleischmann, Sten Eirik Jacobsen | |||
| Bone marrow spawns brain killers. | Health | Costantino Iadecola | |||
| Brain on steroids resists neurodegeneration. | Health | Karen Duff, Mark P. Burns | |||
| Breast cancer progression with a Twist. | Health | Jean Paul Thiery, Matthew Morgan | |||
| Building global networks for human diseases: genes and populations. | Health | Hans-E Hagen, Jan Carlstedt-Duke | |||
| Bystander elimination of antigen loss variants in established tumors. | Health | Michael T. Spiotto, Donald A. Rowly, Hans Schreiber | |||
| Calcium handler mishandles heart. | Health | David A. Kass, Hunter Champion | |||
| CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. | Health | David E. Housman, Wolfgang Bergmeier, Jill R. Crittenden, Yanyu Zhang, Yuqiong Liang, Crystal L. Piffath, Denisa Wagner, Ann M. Graybiel | |||
| cAMP and schwan cells promote axonal growth and functional recovery after spinal cord injury. | Health | Damien Pearse, Fransciso C. Pereira, Alexander Marcillo, Margaret L. Bates, Yerko A. Berrocal, Marie T. Filbin, Mary Bartlett Bunge | |||
| Cancer drug discovery: the wisdom of imprecision. | Health | Andrei V. Gudkov | |||
| Cancer genes and the pathways they control. | Health | Kenneth W. Kinzler, Bert Vogelstein | |||
| Cancer immunotherapy: Breaking the barriers to harvest the crop. | Health | James Allison, Drew Pardool | |||
| Cannabinoids cool the intestine. | Health | George Kunos, Pal Pacher | |||
| Can nicotine treat sepsis? | Health | Lorraine B. Ware, Michael A. Matthay | |||
| Cardiac channelopathies: it's in the genes. | Health | Michael J. Ackerman | |||
| Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. | Health | Ronald M. Evans, Michael D. Schneider, William Lewis, Lihong Cheng, Guoliang Ding, Qianhong Qin, Yao Huang, Nu He, Florence A. Brako, Yan Xiao, Yuqing E. Chen, Qinglin Yang | |||
| CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer. | Health | Paul S. Meltzer, David Sidransky, Jeffrey M. Trent, Yoram Cohen, Zhongmin Guo, Sarel Halachmi, James M. Engles, Mark P. Schoenberg, Jurgen F. Linn, Motonabu Osada, Barry Trink, Guojun Wu, Sarah L. Anzick, Claus F. Eisenberger, Alexey Fomenkov, Mohammad Obaidul Hoque, Kenji Okami, Gabriel Steiner, Chulso Moon, Edward Ratovitski | |||
| Cellular energy sensor balances the scales. | Health | Stephen R. Bloom, Caroline J. Small, David Carling | |||
| Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites. | Health | Phillip Scott, Colby Zaph, Jude Uzonna, Stephen M. Beverly | |||
| Ceramide lances the lungs. | Health | Peter J. Barnes | |||
| Cheating death in the liver. | Health | Gregory J. Gores, Eugenia M. Guicciardi | |||
| Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. | Health | David Lyden, Koichi Hattori, Sergio Dias, Beate Heissig, Larry Witte, Shahin Rafii, Fan Zhang, Daniel J Hicklin, Scott T. Avecilla, Raefael Tejada, Fang Liao, Koji Shido, David K Jin, Travis E Hartman, Neil R Hackett, Ronald G Crystal, Peter Bohlen, Dan Eaton, Fredric de Sauvage | |||
| China's new AIDS policy faces great wall of skepticism. | Health | I-han Chou | |||
| Chipping away at gallstones. | Health | Kerry B. Goralski, Christoper J. Sinal | |||
| Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. | Health | Kevin J. Tracey, Hong Wang, Hong Liao, Mahendar Ochani, Marilou Justiniani, Xinchun Lin, Lihong Yang, Yousef Al-Abed, Haichao Wang, Christine Metz, Edmund J. Miller, Luis Ulloa | |||
| Cities spawn epidemic dengue viruses. | Health | Duane J. Gubler | |||
| Clive Svendsen.(Neuroscientist ) | Health | Paroma Basu | |||
| Cocaine's long run. | Health | George F. Koob, Pietro Paolo Sanna | |||
| Collaboration may be the cure for what ails drug development. | Health | Amy E. Erickson | |||
| Combination stroke therapy: Easy as APC?(activated protein C) | Health | Eng H Lo | |||
| Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know. | Health | Giuseppe Pantaleo, Richard A. Koup | |||
| Creating incentives for genomic research to improve targeting of therapies. | Health | Eric M. Meslin, Barbara J. Evans, David A. Flockhart | |||
| Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis. | Health | David Finegold, Seppo Yla-Herttuala, Kari Alitalo, Tatiana Petrova, Russell Mellor, Robert Ferrell, Camilla Norrmen, Terhi Karpanen, Tomoki Tamakoshi, Peter Mortimer, Dontscho Kerjaschki, Naoyuki Miura | |||
| Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. | Health | Irving Weissman, Samuel Strober, Petra Hoffmann, Miriam Merad, Erik Ranheim, Sarah Slaymaker, Markus G. Manz, Sergio A. Lira, Israel Charo, Donald N Cook, Edgar G. Engleman | |||
| Differentiating the pathologies of cerebral malaria by postmortem parasite counts. | Health | Terrie E. Taylor, J. Wenjiang Fu, Richard A. Carr, Richard O. Whitten, Jeffrey G. Mueller, Nedson G. Fosiko, Susan Lewallen, N. George Liomba, Malcom E. Molyneux | |||
| Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. | Health | Rakesh K. Jain, Lance L. Munn, David P. Ryan, Alan J. Fischman, David T. Scadden, Paul C. Shellito, Helen X. Chen, Dushyant V. Sahani, Gregory Y. Lauwers, Daniel C. Chung, Mari Mino, Yves Boucher, Sergey V. Kozin, Jeffrey W. Clark, Christopher G. Willet, Ricky T. Tong, Emmanuelle di Tomaso, Dan G. Duda, Sanjeeva P. Kalva, Alan C. Hartford, Kenneth S. Cohen, Andrew X. Zhu, Lawrence S. Blaszkowsky | |||
| Disputed expenses at heart of Moncada's Spanish spat.(University College in London) | Health | Xavier Bosch | |||
| Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model. | Health | Eric C. Holland, Lene Uhrbom, Edward Nerio | |||
| Donor APCs are required for maximal GVHD but not for GVL. | Health | Dhanpat Jain, Catherine C. Matte, James Cormier, Ioanna Athanasiadis, Jennifer McNiff, Warren D. Shlomchik, Jinli Liu, Britt E. Anderson | |||
| Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation. | Health | Jeffrey L. Platt, Lori J. West, Anne I. Dipchand, Gregory Wilson, Andrew Ang, Xiaohu Fan, Stacey M. Pollock-BarZiv, Phillip Ruiz | |||
| Easing the brakes on spinal cord repair. | Health | Samuel David, Lisa McKerracher | |||
| Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease. | Health | Vicente E. Torres, Peter C. Harris, Stefan Somlo, Xiaofang Wang, Qi Qian, Vincent H. Gattone II | |||
| Effector CD8(super +) T cells mediate inflammation and airway hyper-responsiveness. | Health | Erwin W. Gelfand, Nobuaki Miyahara, Bradley J. Swanson, Katsuyuki Takeda, Christian Taube, Satoko Miyahara, Taku Kodama, Azzeddine Dakhama, Vanessa L. Ott | |||
| Embedding T cells in the matrix. | Health | Markus Cornberg, Liisa K. Selin | |||
| Embryonic stem cells: staying plastic on plastic. | Health | Fred H. Gage, Kinichi Nakashima, Sophia Colamarino | |||
| Emerging flaviviruses: The spread and resurgence of Japanese encephalitis, West Nile and dengue viruses. | Health | Lyle R. Peterson, Duane J. Gubler, John S. Mackenzie | |||
| EMSY, a BRCA-2 partner in crime. | Health | David M. Livingston | |||
| Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice. | Health | Akira Suzuki, Iichiro Shimomura, Morihiro Matsuda, Junji Takeda, Nobuyasu Komazawa, Gen Kondoh, Wataru Mizunoya, Masanori Iwaki, Toshiyuki Takagi, Yasuyuki Sumikawa, Kazuo Inoue, Tak Wah Mak, Toru Nakano, Tohru Fushiki | |||
| Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.(cytokine signaling-3 ) | Health | Jeffrey S. Flier, Jane K. Howard, Belinda J. Cave, Laura J. Oksanen, Iphigenia Tzameli, Christian Bjorbaek | |||
| Epithelial cells pay a Toll for protection. | Health | Warren Strober | |||
| Escape of malaria parasites from host immunity requires CD4+CD25 regulatory T cells. | Health | Koji Yasutomo, Kenji Kishihara, Kunisuke Himeno, Hajime Hisaeda, Yoichi Maekawa, Shin-ichi Tsukumo, Daiji Iwakawa, Okada Hiroko | |||
| Exotic emerging viral diseases: Progress and challenges. | Health | Thomas W. Geisbert, Peter B. Jahrling | |||
| Experts call for smarter approach to targeted therapies. | Health | Alla Katsnelson | |||
| Explorations in the land of DNA and beyond. | Health | Matthew Meselson | |||
| Expressing what's on your mind: DNA arrays and the brain. | Health | David J. Lockhart, Carrolee Barlow | |||
| Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six - 1 as key metastatic regulators. | Health | Glenn Merlino, Javed Khan, Paul S. Meltzer, Yanlin Yu, Chand Khanna, Lee Helman | |||
| 'Fast-track' drug approvals hit speed bumps in Japan. | Health | Douglas Sipp | |||
| Fatal attraction: Tumors beckon regulatory T cells. | Health | Ethan M. Shevach | |||
| Fatal flaw in baby formula sparks reform in Israeli ministry.(vitamin deficiency) | Health | Luba Vikhanski | |||
| Fat hormones pull their weight in the CNS.(Central nervous system) | Health | Stephen C. Woods, Randy J. Seeley, David A. D'Alessio | |||
| Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain. | Health | Steven A. Goldman, Theodore H. Schwartz, Martha S. Windrem, Martha C. Nunes, Robert A. Goodman, Guy II McKhann, Neeta S. Roy | |||
| Finally, mice with CF lung disease.(cystic fibrosis) | Health | Raymond A. Frizzell, Joseph M. Pilewski | |||
| Flue strikes the hygiene hypothesis. | Health | Dale T. Umetsu | |||
| Fragile fugue: p53 in aging, cancer and IGF signaling. | Health | Judith Campisi | |||
| From chemical warfare to breast cancer management. | Health | Elwood Jensen | |||
| From Pasteur to genomics: Progress and challenges in infectious diseases. | Health | Rino Rappuoli | |||
| From plankton to pathogen recognition. | Health | Robert L. Modlin, Genhong Cheng | |||
| Gene delivery goes global. | Health | Clare E. Thomas | |||
| Gene networks go global. | Health | Tanita Casci | |||
| Genetic, cellular and immune approaches to disease therapy: Past and future. | Health | Gary J. Nabel | |||
| Genetic clues to the pathogenesis of Parkinson's disease. | Health | Miquel Vila, Serge Przedborski | |||
| Glycosylation eases muscular dystrophy. | Health | Francesco Muntoni, Martin Brockington, Susan C. Brown | |||
| gp41: HIV's shy protein. | Health | Dennis R. Burton, Michael B. Zwick, Erica O. Saphire | |||
| Halted trial renews questions about cancer vaccines. | Health | Peter Vermij, Martina Frei | |||
| Hematopoietic stem cells get closer to the bone. | Health | Connie Eaves | |||
| Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. | Health | Jane E. Salmon, Guillermina Girardi, Patricia Redecha | |||
| Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. | Health | Jie An, Deborah M. Muoio, Masakazu Shiota, Yuka Fujimoto, Gary W. Cline | |||
| HIV escape: there and back again. | Health | John D. Altman, Mark B. Feinberg | |||
| HIV evolution: CTL escape mutation and reversion after transmission. | Health | A.J. Leslie, K.J. Pfafferott, P. Chetty, R. Draenert, M.M. Addo | |||
| Homeostatic proliferation is a barrier to transplantation tolerance. | Health | Mohamed H. Sayegh, James F. Markmann, Laurence A. Turka, Zihao Wu, Steven J. Bensinger, Jidong Zhang, Chuangqi Chen, Xueli Yuan, Xiaolun Huang, Alireza Kassaee, Bruce R. Rosengard, Wayne W Hancock | |||
| How a jolt and a bolt in a dentistEs chair revolutionized cataract surgery. | Health | Joseph L. Goldstein | |||
| How I became one of the fathers of a superfamily. | Health | Pierre Chambon | |||
| HTLV - 1 encoded p30(super II) is a post - transcriptional negative regulator of viral replication. | Health | Tom Misteli, Genoveffa Franchini, Christophe Nicot, Jakke R. Fullen, Gerald L. Princler, Miroslav Dundr, Norma Alonzo, Risaku Fukumoto, Julie M. Johnson, David Derse | |||
| HTLV-1 sweet-talks its way into cells.(Human T-lymphotropic virus I) | Health | Julie Overbaugh | |||
| Human lupus T cells resist inactivation and escape death by upregulating COX-2. | Health | Syamal K. Datta, Li Zhang, Luting Xu, Yajun Yi, Hee-Kap Kang | |||
| Hypertension with a grain of salt. | Health | Josef Penninger, Ursula Danilczyk | |||
| Identification of a new human coronavirus. | Health | Lia van der Hoek, Wilma Vermeulen-Oost, Katja C. Wolthers, Jos Kaandorp, Ben Berkhout, Joke Spaargaren, Dillen Pauline M.E. Wertheim-van, Ron J.M. Berkhout, Krzysztof Pyrc, Jebbink Maarten F. | |||
| Increased airway epithelial Na(super +) absorption produces cystic fibrosis-like lung disease in mice. | Health | Richard C. Boucher, Marcus Mall, Barbara R. Grubb, Jack R. Harkema, Wanda K. O'Neal | |||
| India, Japan launch HIV vaccines to match local strains. | Health | K.S. Jayaraman, I-han Chou | |||
| Inflamed about obesity. | Health | Michael Lehrke, Mitchell A. Lazrar | |||
| Influenza, an important disease in humans and animals, is caused by viruses that undergo continuous antigenic change and that possess an animal reservoir. Hence, it is reported that the imposition of new rules for working with infectious influenza viruses under high security and high containment conditions would stifle scientific progress. | Health | J. S. M. Peiris, Y. Guan, K. Y. Yuen | |||
| Influenza: Old and new threats. | Health | Peter Palese | |||
| Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator. | Health | Gordon G. Power, Alan N. Schechter, Mark T. Gladwin, Howard Shields, Christian J. Hunter, Selamawit Tarekegn, Andrew O. Hopper, Andre Dejam, Arlin B. Blood, Roberto F. Machado, Neda Mulla | |||
| Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling. | Health | Hiroshi Ueda, Makoto Inoue, Md. Harunor Rashid, Ryousuke Fujita, James J. A. Contos, Jerold Chun | |||
| Injection of recombinant human type VII collagen restores collagen function in dystrophic epidermolysis bullosa. | Health | David T. Woodley, Wei Li, Douglas R. Keene, Tom Atha, Yi Huang, Kathi Lipman, Mei Chen | |||
| Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein. | Health | Xiao Yan Zhou, Nobuyuki Shibusawa, Karuna Naik, Delia Porras, Karla Temple, Fredric E. Wondiford, Matthew J. Brady, Michael W. Roe, Kelly Kaihara, Hesheng Ou | |||
| Iraq's public health infrastructure a casualty of war. | Health | Paroma Basu | |||
| Irving Weissman. | Health | Kris Novak | |||
| Isolated small intestinal segments support auxiliary livers with maintenance of hepatic functions. | Health | Sanjeev Gupta, Brigid Joseph, Ekaterine Berishvili, Daniel Benten, Vinay Kumaran, Ekaterine Liponova, Kuldeep Bhargava, Christopher Palestro, Zurab Kakabadze | |||
| It is ethical to transplant human stem cells into nonhuman embryos. | Health | Cynthia B. Cohen, Derek van der Kooy, Philip Karpowicz | |||
| Know thine enemy. | Health | Daniel Carucci | |||
| LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies. | Health | Ichizo Nishino, Kevin P. Campbell, Rita Barresi, Daniel E. Michele, Motoi Kanagawa, Hollie A. Harper, Sherri A. Dovico, Jakob S. Satz, Steven A. Moore, Wenli Zhang, Harry Schachter, Jan P. Dumanski, Ronald D. Cohn | |||
| Learning to take a deep breath-with BDNF.(Brain-Derived Neurotrophic Factor) | Health | John M. Bekkers, George B. Richerson | |||
| Lipid unites disparate syndromes of sepsis. | Health | Haichao Wang, Kevin J. Tracey, Christopher J. Czura | |||
| List of 'prurient' research stirs fear, anger among US scientists. | Health | Vicki Brower | |||
| London calling for British medical research institute.(National Institute for Medical Research) | Health | Laura Spinney | |||
| Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. | Health | Adriano Aguzzi, Hermann Wagner, Shizuo Akira, Mathias Heikenwalder, Tobias Junt, Rolf Zinkernagel, Magdalini Polymeniduo, Christina Sigurdson | |||
| Magic bullets melt fat. | Health | Marc L. Reitman | |||
| Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor.(glycogen synthase kinase-3) | Health | Paul Greengard, Ali H. Brivanlou, Laurent Meijer, Noboru Sato, Leandros Skaltsounis | |||
| Marc Tessier-Lavigne.(scientist) | Health | apoorva Mandavilli | |||
| Mark Mattson. | Health | Helen Pearson | |||
| Melanocortin receptors weigh in. | Health | I. Sadaf Farooqi, Stephen O'Rahilly, Giles S.H. Yeo | |||
| Memory may not need reminding. | Health | Robert A. Seder, David L. Sacks | |||
| Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiopathy in response to pathological biomechanical stress. | Health | John M. Shelton, James A. Richardson, Eric N. Olson, Christian Kuhn, Hugo A. Katus, Doris Gehring, Nobert Frey, Tomasa Barrientos, Derk Frank, Hartmut Rutten, Matthias Lutz, Beverly Rothermel, Rhonda Bassel-duby, Hill Joseph A. | |||
| Micromanaging insulin secretion. | Health | Michael P. Czech, Craig C. Mello | |||
| Modeling epidemics of multidrug-resistant M.tuberculosis of heterogeneous fitness. | Health | Ted Cohen, Megan Murray | |||
| Modeling the emergence of the 'hot zones': tuberculosis and the amplification dynamics of drug resistance. | Health | Sally M. Blower, Tom Chou | |||
| Modern science versus the stigma of obesity. | Health | Jeffrey M. Friedman | |||
| Modifying quinolone antibotics yields new anxiolytics. | Health | Timothy B C . Johnstone, Derk J. Hogenkamp, Leanne Coyne, Jiping Su, Robert F. Halliwell, Minhtam B. Tran, Ryan F. Yoshimura, Wen-Yen Li, Jeff Wang, Kelvin W. Gee | |||
| Molecular constraints to interspecies transmission of viral pathogens. | Health | Robert Webster, Richard Webby, Erich Hoffmann | |||
| Molecular determinants of resistance to antiandrogen therapy. | Health | Michael G. Rosenfeld, Charles L. Sawyers, Sung Hee Baek, Charlie D. Chen, Derek S. Welsbie, Chris Tran, Randy Chen, Robert Vesella | |||
| Molecular pathways to neurodegeneration. | Health | Stuart A. Lipton, Robert Schwarzenbacher, Ella Bossy-Wetzel | |||
| Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation. | Health | Roderick T. Bronson, Jonathan A. Epstein, Benjamin G. Neel, D. Gary Gilliland, Toshiyuki Araki, Fraz A. Ismat, M. Golam Mohi, Ilfor R. Williams, Jeffrey L. Kutok, Wentian Yang, Lily I. Pao | |||
| mToR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. | Health | Massimo Loda, Todd R. Golub, Timothy J. McDonnell, Heidi A. Lane, Pradip K. Majumder, Phillip G. Febbo, Rachel Bikoff, Raanan Berger, Xue Qi, James Brugarolas, Judith Manola, Louis M. McMahon, William R. Sellers | |||
| Mutation of the COG complex subunit gene COG7 causes a lethal congenital disorder.(conserved oligomeric Golgi) | Health | Xiaohua Wu, Monty Krieger, Richard A. Steet, Ognian Bohorov, Jaap Bakker, Hudson H. Freeze, John Newell, Leo Spaapen, Stuart Kornfeld | |||
| Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. | Health | Milton Finegold, Markus Grompe, William H. Fleming, Mark Foster, Susan Olson, Yassmine Akkari, Holger Willenbring, Alexis S. Bailey, Craig Dorrell | |||
| Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakouts. | Health | Mark S. Forman, John Q. Trojanowsli, Virginia M. Y. Lee | |||
| Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway. | Health | Masaru Okabe, Reiko Hanada, James Todd Pearson, Hiroshi Hosoda, Nobuhiro Fukushima, Ryota Serino, Hitoshi Teranishi, Mamoru Kurokawa, Noboru Murakimi, Mikiyasu Shirai, Yoshihiko Fukue, Hironobu Yoshimatsu, Yoichi Ueta, Masahito Ikawa, Kenji Kangawa, Hiroaki Fujihara | |||
| Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury. | Health | Peter H. Krammer, Deana Demjen, Cecilia Zuliani, Ulrich A. Hirt, Ana Martin-Villalba, Stefan Klussmann, Bram Stieltjes, Henning Walczak, Susanne Kleber, Corinna Metzger, Werner Falk, Marco Essig | |||
| New vaccines enter fray in fight against tuberculosis. | Health | Hannah Hoag | |||
| Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allpregnanolone. | Health | Lisa D. Griffin, Wenhui Gong, Lucie Verot, Synthia H. Mellon | |||
| Nogo puts the brake on vascular lesions. | Health | Elaine W. Raines | |||
| Noninvasive cineangiography by magnetic resonance global coherent free precession. | Health | Raymond J. Kim, Robert M. Judd, Wolfgang G. Rehwald, Enn-Ling Chen | |||
| Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics. | Health | Roland Contreras, Callewaert, Nico; Vlierberghe, Hans Van, Annelies Van Hecke, Wouter Laroy, Joris Delanghe | |||
| Noninvasive electrocardiographic imaging for cardiac electrophysiology and arrhythmia. | Health | Yoram Rudy, Charulatha Ramanathan, Kyungmoo Ryu, Raja N. Ghanem, Ping Jia | |||
| Nonsteroidal anti-inflammatory drugs lower A(beta)42 and change presenilin 1 conformation. | Health | Bradley T. Hyman, Matthew P. Frosch, Alberto Lleo, Lauren Herl, Amy Deng, Oksana Berezovska, Susan Raju, Brian J. Bacskai, Michael Irizarry | |||
| Not asleep, not quite awake. | Health | J. Gregor Sutcliffe, Luis de Lecea | |||
| No tolerance for depletion.(T-cell depletion) | Health | Hugh Auchincloss | |||
| Nucleus hears axon's pain. | Health | Armin Blesch, Mark H. Tuszynski | |||
| Nutrient sensor links obesity with diabetes risk. | Health | Barbara B. Kahn, Mary-Elizabeth Patti | |||
| Otmar Wiestler. | Health | Gunjan Sinha | |||
| Outsourcing clinical trials to India rash and risky, critics warn. | Health | K.S. Jayaraman | |||
| Ovarian transplants restore fertility in cancer patients. | Health | Leslie Harris O' Hanlon | |||
| Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway. | Health | Kazuwa Nakao, Michio Suda, Yoshihiro Ogawa, Akihiro Yasoda, Yasato Komatsu, Hideki Chusho, Takashi Miyazawa, Ami Ozasa, Masako Miura, Tatsuya Kurihara, Tomohiro Rogi, Shoji Tanaka, Naohisa Tamura | |||
| Oxidative stress in neurodegeneration: cause or consequence? | Health | Julie K. Anderson | |||
| P2X7 receptor inhibition improves recovery after spinal cord injury. | Health | Maiken Nedergaard, Steven A. Goldman, Gregory Arcuino, Xiaohai Wang, Jane Lin, Li, Pingjia ;, Qing Song Liu, Takahiro Takano, Pinglan Wan, Wei Wei Peng, Qiwu Xu | |||
| PAF - mediated pulmonary edema: A new role for acid sphingomyelinase and ceramide. | Health | Arthur S. Slutsky, Helmut Brade, Yumiko Imai, Rolf Goggel, Stefan Schutze, Stefan Uhlig, Supandi Winoto - Morbach, Karsten Lindner, Stefan Ehlers, Erich Gulbins, Gabriele Vielhaber, Lore Brade | |||
| Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques. | Health | Ron A.M. Fouchier, Bart L. Haagmans, Thijs Kuiken, E. Martina Byron, Guus Rimmelzwaan | |||
| Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis. | Health | Frank J. Gonzalez, Fred S. Harman, Christropher J. Nicol, Holly E. Marin, Jerrold M. Ward, Jeffrey M. Peters | |||
| PET concerns in bevacizumab treatment.(Positron Emission Tomography) | Health | ||||
| PGC-1 promoters insulin resistance in liver through PPAR-(alpha)-dependent induction of TRB-3. | Health | Ronald M. Evans, Stephan Herzig, Jerrold Olefsky, Seung-Hoi Koo, Hiroaki Satoh, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Mark Montminy | |||
| Philippa Marrack. | Health | Kendall Powell | |||
| PKC-alpha regulates cardiac contractility and propensity toward heart failure. | Health | Julian C Braz, Kimberly Gregory, Anand Pathak, Wen Zhao, Bogachan Sahin | |||
| Plague of my people. | Health | Pascoal Mocumbi | |||
| Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide. | Health | Hidenori Ichijo, Masatsugu Hori, Hideaki Kaneto, Takeshi Miyatsuka, Matsuoka Taka-ak, Yoshitaka Kajimoto, Yoshimitsu Yamasaki, Yoshihisa Nakatani, Dan Kawamori, Munehide Matsuhisa | |||
| Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration . | Health | Edward H. Koo, Rapheal Kopan | |||
| Power to the people. | Health | Declan Butler | |||
| PPARs and the complex journey to obesity. | Health | Ronald M. Evans, Grand D. Barish, Yong-Xu Wang | |||
| Prevention of cholesterol gallstone disease by FXR agonist in a mouse model.(farnesoid X receptor) | Health | David J. Mangelsdorf, Angie L. Bookout, Antonio Moschetta | |||
| Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. | Health | Daniel J. Ceradini, Matthew J. Callaghan, Anita R. Kulkarni, Oren M. Tepper, Nicholas Bastidas, Mark E. Kleinman, Jennifer M. Capla, Robert D. Galiano, Jamie P. Levine, Geoffrey C. Gurtner | |||
| Prospects for an AIDS vaccine. | Health | Ronald C. Desrosiers | |||
| Protein aggregation and neurodegenerative disease. | Health | Christopher A. Ross, Michelle A. Poirier | |||
| Protein microarrays for multiplex analysis of signal transduction pathways. | Health | Joerg Ermann, Steven M. Chan, Leon Su, Garrison C. Fathman, Paul J. Utz | |||
| PrPSc accumulation in myocytes from sheep incubating natural scrapie. | Health | O. Andreoletti, Simon S., C. Lacroux, N. Morel, G. Tabouret, A. Chabert, F. Corbiere, Ferre P., Foucras G., H. Laude, Eychenne F., Grassi J., F. Schelcher | |||
| Putting the heat on ALS.(amyotrophic lateral sclerosis ) | Health | Susanna C. Benn, Robert H. Jr Brown | |||
| Recent microarray advances help unravel biological complexities. | Health | Alan Dance | |||
| Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses. | Health | Ram Kumar Mathur, Amit Awasthi, Pallavi Wadhone, Boppana Ramanamurthy, Bhaskar Saha | |||
| Recognition of tumor blood vessel normalization as a new antiangiogenic concept. | Health | Rakesh K. Jain, Kurt Hellmann | |||
| Recognizing differences. | Health | Ezzie Hutchinson | |||
| Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. | Health | Adrian V.S. Hill, Sarah C. Gilbert, Helen McShane, Ansar A. Pathan, Clare R. Sander, Sheila M. Keating, Kris Huygen, Helen A. Fletcher | |||
| Redistricting the retroviral restriction factors. | Health | Warner C. Greene | |||
| Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways. | Health | Melinda A. Lee, Mason W. Freeman, Kathryn J. Moore, Harry Bjorkbacka, Staphanie Koehn, Kristen Halmen, Douglas T. Golenbock, Vidya V. Kunjathoor, Christine M. Ordija, Terry Means, Andrey D. Luster | |||
| Regional ethics organizations for protection of human research participants. | Health | Ezekiel J. Emanuel, Anne Wood, Christine Grady | |||
| Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. | Health | Peter Carmeliet, Mattias Belting, Michael I. Dorrell, Staffan Sandgren, Edith Aguilar, Martin Friedlander, Wolfram Ruf, Jasimuddin Ahamaed, Aandrea Dorfleutner, Barbara M. Mueller | |||
| Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. | Health | Richard Heller, Drew Pardoll, Tianhong Wang, Guilian Niu, Lyudmila Burdelya, Kenneth Shain, Shumin Zhang, Raka Bhattacharya, Dmitry Gabrilovich, Domenico Coppola, Julian Eltinge, Richard Jove, Hua Yu | |||
| Regulatory T cells and mechanisms of immune system control. | Health | Anne O'Garra, Paulo Vieira | |||
| Research on infectious diseases requires better coordination. | Health | Robert G. Ridley | |||
| Reticulon family members modulate BACE1 activity and amyloid-B peptide generation. | Health | Wanxia He, Isam Qahwash, Xiang-You Hu, Ansi Chang, Riqiang Yan, Yifeng Lu | |||
| Reversal of obesity by targeted ablation of adipose tissue. | Health | Renata Pasqualini, Wadih Arap, Lawrence Chan, Mikhail G. Kolonin, Pradip K. Saha | |||
| Reversion of CTL escape-variant immunodeficiency viruses in vivo.(cytotoxic T-lymphocyte ) | Health | Thomas C Friedrich, Elizabeth J. Dodds, Levi J. Yant, Lara Vojnov, Richard Rudersdorf | |||
| RNAi quashes polyQ. | Health | Natasha J. Caplen | |||
| RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. | Health | Harry T. Orr, Beverly L. Davidson, Haibin Xia, Steven L. Eliason, Qinwen Mao, Scott Q. Harper, Ines H. Martins, Henry L. Paulson, Linda Yang, Robert M. Kotin | |||
| Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.(IsGylation) | Health | Ming Yan, Kenneth J. Ritchie, Keun Il Kim, Chang S. Hang, Dabralee Rosario, Li Li, Juan Carlos de la Torre, Dong-Er Zang | |||
| Role of STAT - 3 in regulation of hepatic glyconeogenic genes and carbohydrate metabolism in vivo. | Health | Kiyoshi Takeda, Shizuo Akira, Masato Kasuga, Hiroshi Inoue, Toshiyuki Mori, Hashimoto, Naoko; Kido, Yosiaki, Shiyu Jin, Haga, Sanae;, Michitaka Ogawa, Hiroshi Sakaue, Michihiro Matsumoto, Kensuke Furukawa, Kiyoshi Teshigawara | |||
| Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections. | Health | Hubert Kalbacher, Christopher Weidenmaier, John F. Kokai Kun, Sascha A. Kristian, Tanya Chanturiya | |||
| Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle. | Health | Jin Zhang, Takahiro Iwamoto, Satomi Kita, Mordecai P. Blaustein, Yuji Arai, Shigeru Yoshida, Koji Wakimoto, Issei Komuro, Takeshi Katsuragi | |||
| Save the child. | Health | Stephen Hoffman | |||
| Scientists divided on relevance of race in medical research. | Health | Damaris Christensen | |||
| Scientists stumped by test that promises tailored treatment. | Health | Alla Katnelson | |||
| Scientists turn anxious eyes to Bush's second term. | Health | Jonathan Knight | |||
| Seeing the forest for the trees. | Health | Simon Frantz | |||
| Selecting the right patient for tumor therapy. | Health | Carlos L. Srteaga | |||
| Selective inactivation or reconstitution of adenosine A(sub 2A) receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury. | Health | Liqun Yu, Zhihong Huang, Juliana Mariania, Yumei Wang, Michael Moskowitz | |||
| Selective inhibition of NF-kappa blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo. | Health | Hiroaki Saito, Kazuhiro Aoki, Eijiro Jimi, Fulvio D' Acquisto, Michael J. May, Shankar Ghosh, Keiichi Ohya, Koji Okabe, Hidefumi Fukushima, Okamoto; Fujio, Takefumi Kojima, Testuo Sudo, Ichiro Nakamura | |||
| S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. | Health | Christian Schoneich, Richard A. Cohen, Takeshi Adachi, Robert M. Weisbrod, David R. Pimentel, Victor S. Sharov, Jia Ying | |||
| Shock factor shed by microbe. | Health | Jonathan Cohen | |||
| Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1 (+) leukemia cells. | Health | Stephen G. Emerson, Andrzej Ptasznik, Yuji Nakata, Anna Kalota, Alan M. Gewirtz | |||
| Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.(rectivation of p53-HDM-2 and induction of tumor cell apoptosis) | Health | Natalia Issaeva, Marina Protopopova, Przemyslaw Bozko, Martin Enge, Lisette G.G.C. Verhoef, Maria Masucci | |||
| Social and environmental risk factors in the emergence of infectious diseases. | Health | Robin A. Weiss, Anthony J. McMichael | |||
| Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity.(Cytokine signalling-3) | Health | Kenneth R. Chien, Akihiko Yoshimura, Hiroyuki Mori, Reiko Hanada, Toshikatsu Hanada, Daisuke Aki, Ryuichi Mashima, Hitomi Nishinakumara, Takehiro Torisu, Hideo Yasukawa | |||
| Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cell. | Health | Jonathan D. Licht, Jose M. Polo, Tania Dell Oso, Stella Maris Ranuncolo, Leandro Cerchietti, David Beck Beck, Gustavo Da Silva F., Gilbert Prive G., Ari MelniK | |||
| Spinal cord alive and kicking. | Health | Christopher E. Henderson, Catherine Barthelemy | |||
| Sporadic ALS: Blame it on the editor. | Health | Stuart A. Lipton | |||
| Staphylococcal protein A inflames the lungs. | Health | Staffan Normark, Birgitta Henriques Normak, Anna Norrby-Teglund | |||
| Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1. | Health | Marisa Gomez, Aram Lee, Bharat Reddy, Amanda Muir, Grace Soong, Allyson Pitt, Ambrose Cheung, Alice Prince | |||
| Stem cells bank on ATM machine.(mutations in the ATM gene cause ataxia telangiectasia) | Health | Anthony D. Whetton | |||
| Stem cells for Parkinson disease and ALS: replacement or protection? | Health | J. William Langston, Clive N. Svendsen | |||
| Stem cell therapy for human neurodegenerative disorders-how to make it work. | Health | Olle Lindvall, Zaal Kokaia, Alberto Martinez-Serrano | |||
| Strength in unity. | Health | Carter Diggs, Sarah Ewart, Melinda Moree | |||
| Suppressing the self in rheumatoid arthritis. | Health | Robert S. Mittler | |||
| Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor. | Health | Ettore Appella, Li Hua Wang, Xiao Yi Yang, Xiaohu Zhang, Kelly Mihalic, Weihua Xiao, Ying-Xin Fan, O M Zack Howard, Andrew T. Maynard, Farrar William L. | |||
| Suramin inhibits death receptor-induced apoptosis in vitro and fulminant apoptotic liver damage in mice. | Health | Alexander L. Gerbes, Sore T. Eichhorst, Andreas Krueger, Susanne Muerkoster, Stefanie C. Fas, Alexander Golks, Krammer Peter H., Manfred Bilzer, Opelz Christine, Schubert Louise, Uwe Gruetzner | |||
| Sweet relief for Huntington disease. | Health | Masahisa Katsuno, Gen Sobue, Hiraoki Adachi | |||
| Systemic delivery of genes to striated muscle using adeno-associated viral vectors. | Health | Leonard Meuse, Daniel G. Miller, Jeffrey S. Chamberlain, David W. Russell, Paul Gregorevic, Michael J. Blankinship, James M. Allen, Robert W. Crawford | |||
| Taking aim at mosquitoes. | Health | Janet Hemingway | |||
| Tangling with hypothermia. | Health | Jesus Avila, Javier Diaz-Nido | |||
| Tanning before transplant: Lancing the Langerhans cell. | Health | Stephen G. Emerson | |||
| Targeting angiogenasis with a conjugate of HPMA copolymer and TNP-470. | Health | Roni Satchi Fainaro, Mark Puder, Hai T. Tran, David A. Sampson | |||
| TCR affinity and negative regulation limit autoimmunity. | Health | Pamela S. Ohashi, Josef M. Penninger, Bernhard Odermatt, Demetrius Moskophidis, Nicholas R.J. Gascoigne, Alisha R. Elford, Matthew A. Gronski, Jonathan M. Boulter, Linh T. Nguyen, Kaisa Holmberg, Elissa K. Deenick, Hee Kim O., Awen Gallimore | |||
| THC: moderation during implantation.(tetrahydrocannabinol) | Health | Daniele Piomelli | |||
| The 5-lipoxygenase pathways promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm. | Health | Daniel J. Rader, Jilly F. Evans, Andreas J.R. Habenicht, Lei Zhao, Jinjin Fan, Katharina Lotzer, Frederique Pedrono, Rolf Garbner, Michael P.W. Moos, Rainer Spanbroek, Sandra Schmidt, Nicole John, Brigitte Kaiser, Jisong Cui, Li Huang, Colin D. Funk | |||
| The controversial protein-only hypothesis of prion propagation. | Health | Claudia Soto, Joaquin Castilla | |||
| The heart of the matter.(Whether hematopoietic stem cells can heal damaged hearts) | Health | Helen Pearson | |||
| The idiotypic network in autoimmunity: antibodies that bind antibodies that bind antibodies. | Health | Yehuda Shoenfeld | |||
| The invisible victims. | Health | Robert Snow | |||
| The long and winding road. | Health | Declan Butler, Julie Clayton | |||
| The membrane - cytoskeleton linker ezrin is necessary for osteosarcoma metastasis. | Health | Chand Khanna, Lee Helman, Xiaolin Wan, Choh Yeung, Stephen M. Hewitt, Seuli Bose, Osarenoma Olomu, Richard Gorlick, Arnulfo Mendoza | |||
| The mosquito's innate sting. | Health | Allan Saul | |||
| The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. | Health | Wolfgang Loscher, Michael A. Rogawski | |||
| The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers. | Health | Karen Smith-McCune, Kwai Wa Cheng, John P. Lahad, Wen-lin Kuo, Anna Lapuk, Kyosuke Yamada, Nelly Auersperg, Jinsong Liu, Karen H. Lu, David Fishman, Joe W. Gray, Gordon B. Mills | |||
| Therapeutic cloning gives silenced genes a second voice. | Health | Kris Novak | |||
| Therapeutic dendritic-cell vaccine for chronic HIV-1 infection. | Health | Jean-Marie Andrieu, Wei Lu, Luiz Claudio Arraes, Wylla Tatiana Ferreira | |||
| Therapeutic effects of lysophosphatidylcholine in experimental sepsis. | Health | Ji - Jang Yan; Jun - Sub Jung; Jung - Eun Lee, Jongho Lee; Sung - Ho Huh; Hee - Sung Kim, Kyeong Cheon Jung; Jae - Young Cho; Ju - Suk Nam, Hong - Won Suh; Yung - Hi Kim, Dong - Keun Song | |||
| The refrain in Spain is that Barbacid is to balme.(Mariano Barbacid)(Spanish National Cancer Center) | Health | Xavier Bosch | |||
| The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. | Health | Pier Paolo Pandolfi, Carlos Cordon-Cardo, Wei Xu, Li Ma, David Ruggero, Lorenzo Montanaro, Paola Londei | |||
| The two-timing thyroid. | Health | Stephen B. Liggett | |||
| The use and analysis of microarray data. | Health | Atul Butte | |||
| The worm has turned. | Health | Charlotte Schubert | |||
| Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C. | Health | John H. Griffin, Jose A. Fernandez, Berislav Zlokovic, Dong Liu, Tong Cheng, Huang Guo, Xiaomei Song | |||
| Tolerance tag team. | Health | Dirk Homann, Matthias von Herrath | |||
| Toll-like receptors 3 mediates West Nile virus entry the brain causing lethal encephalitis. | Health | Richard A. Flavell, Lena Alexopoulou, Erol Fikrig, Tian Wang, John F. Anderson, Terrence Town | |||
| TORward AKTually useful mouse models. | Health | Charles L. Sawyers, Ingo K. Mellinghoff | |||
| Towering science: an ounce of creativity is worth a ton of impact. | Health | Joseph L. Goldstein | |||
| Tracking metastatic tumor cell extravasations with quantum dot nanocrystals and fluorescence emission-scanning microscopy. | Health | Evelyn B. Voura, Hedi Mattoussi, Jyoti K. Jaiswal, Sanford M. Simon | |||
| Transcriptional analysis of targets in multiple sclerosis. | Health | Lawrence Steinman, Scott Zamvil | |||
| Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. | Health | Steven F. Dowdy, Jehangir S Wadia, Radu V. Stan | |||
| Transplantation tolerance: babies take the first step. | Health | Jagdeep S. Obhrai, Fadi G Lakkis | |||
| Transporter of a malaria catastrophe. | Health | Thomas E. Wellems | |||
| Trans-splicing repair of CD40 ligand deficiency results in naturally regulated correction of a mouse model of hyper-IgM X-linked immunodeficiency. | Health | Ronald G. Crystal, Martin L. Lesser, Minoru Tahara, Robert G. Pergolizzi, Hiroyasu Kobayashi, Anja Krause, Karsta Luettich | |||
| Treasures and traps in genome-wide data sets: Case examples from yeast. | Health | Elizabeth A. Winzeler, Bjorn Grunenfelder | |||
| Treating cancer's kinase addiction. | Health | Jose Baselga, Joaquin Arribas | |||
| Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice.(amyotrophic lateral sclerosis ) | Health | Linda Greensmith, Kieran, Dairin; Kalmar, Bernadett, James R.T. Dick, Joanna Riddoch-Contreras, Geoffrey Burnstock | |||
| Trehalose alleviates polyglutamine - mediated pathology in a mouse model of Huntington disease. | Health | Motomasa Tanaka, Sanyong Niu, Hiroshi Doi, Munenori Nekooki, Nobuyuki Nukina, Machida Yoko, Tetsurou Ikeda, Masaru Kurosawa, Nihar R. Jana | |||
| Turning up the heat in the fat cell. | Health | Domenico Accili, Luca Valenti | |||
| Two - photon fluorescence correlation microscopy reveals the two - phase nature of transport in tumors. | Health | Rakesh K. Jain, Robert B. Campbell, Yves Boucher, Alexandrakis, George; Brown, Edward B., Tong, Ricky T.; McKee, Trevor D. | |||
| Type 1 diabetes: focus on prevention. | Health | Harald von Boehmer | |||
| UK autism fracas fuels calls for peer review reform. | Health | Laura Spinney | |||
| Urgently needed: a filter for the HIV-1 vaccine pipeline. | Health | Dennis R. Burton, John P. Moore | |||
| US pressures publishers to honor trade embargoes. | Health | Potter Wickware | |||
| Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity. | Health | M. Reza Dana, J. Wayne Streilein, Chen, Lu ; Hamrah, Pedram, Cursiefen, Claus ; Zhang, Qiang, Bronislaw Pytowski | |||
| Vascular endothelial growth (VEGF) induces remodeling and enhances T(sub H)2-mediated sensitization and inflammation in the lung. | Health | Vineet Bhandari, Chun Geun Lee, Robert J. Homer, Lauren Cohn, Holger Link, Peter Baluk, Svetlana Chapoval, Min Jong Kang, Yoon Keun Kim | |||
| VEGF obstructs the lungs. | Health | Marc E. Rothenberg | |||
| Vitamin A helps gut T cells find their way in the dark. | Health | Bengt Johansson-Lindbom, William W. Agace | |||
| Volumetric computed tomography (VCY): A new technology for noninvasive, high-resolution monitoring of tumor angiogenesis. | Health | Kiessling, Fabian; Greschus, Sussane, Lichy, Matthias P.; Bock, Michael, Fink, Christian; Vosseler, Silvia, Moll, Jens; Fusening, Norbert E., Traupe, Horst; Semmler, Wolfhard | |||
| VX-680, a potent and selective small-molecule inhibitor of the Aurora-kinases, suppresses tumor growth in vivo. | Health | Elizaeth A. Harrington, David Bebbington, Jeff Moore, Richele K. Rasmussen, Abi O Ajose Adeogun | |||
| West Nile virus: Crossing the blood-brain barrier. | Health | Michael S. Diamond, Robyn S. Klein | |||
| When are research risks reasonable in relation to anticipated benefits? | Health | Charles Weijer, Paul B. Miller | |||
| Where did it go wrong? | Health | Amir Attaran | |||
| Winning the drugs war. | Health | Robert Ridley, Yeya Tuure | |||
| Withdrawal syndrome. | Health | ||||
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