Cell 2003 - Abstracts
| Cell 2003 | |||||
| Title | Subject | Authors | |||
|---|---|---|---|---|---|
| A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. | Biological sciences | Philippe Marambaud, Paul H. Wen, Anindita Dutt, Junichi Shioi, Akihiko Takashima, Robert Siman, Nikolaos K. Robakis | |||
| A C. elegans sperm TRP protein required for sperm-egg interactions during fertilization. | Biological sciences | Paul W. Sternberg, X.-Z Shawn Xu | |||
| A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans. | Biological sciences | Jonathan T. Pierce-Shimomura, Antonello Bonci, Steven L. McIntire, Andrew G. Davies, Hongkyun Kim, Miri K. VanHoven, Tod R. Thiele, Cornelia Bargmann I. | |||
| ACF7: an essential integrator of microtubule dynamics. | Biological sciences | Elaine Fuchs, Iakowos Karakesisoglou, Ellen Wong, Atsuko Kodama, Alec Vaezi | |||
| Actin dynamics control SRF activity by regulation of its coactivator MAL.(serum response factor) | Biological sciences | Richard Treisman, Francesc Miralles, Guido Posern, Alexia-Ileana Zaromytidou | |||
| Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. | Biological sciences | Richard A. Cerione, Wen Jin Wu, Shine Tu | |||
| Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. | Biological sciences | Don W. Cleveland, Ariane Abrieu, Yinghui Mao | |||
| A "dock, lock, and latch" structural model for a staphylococcal adhesin binding to fibrinogen. | Biological sciences | Stacey Davis, Magnus Hook, Karthe Ponnuraj, M. Gabriela Bowden, S. Gurusiddappa, Dwight Moore, Damon Choe, Yi Xu, Sthanam V. L. Narayana | |||
| Adult cardiac stem cells are multipotent and support myocardial regeneration. | Biological sciences | Piero Anversa, Stefano Chimenti, Bernardo Nadal-Ginard, Antonio P. Beltrami, Konrad Urbanek, Jan Kajstura, Annarosa Leri, Ezio Musso, Laura Barlucchi, Daniele Torella, Mathue Baker, Federica Limana, Hideko Kasahara, Marcello Rota | |||
| Aging reduces proliferative capacities of liver by switching pathways of C/EBP(alpha) growth arrest. | Biological sciences | Polina Iakova, Samir S. Awad, Nikolai A. Timchenko | |||
| A global control region defines a chromosomal regulatory landscape containing the HoxD cluster. | Biological sciences | Denis Duboule, Francois Spitz, Federico Gonzalez | |||
| AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. | Biological sciences | Bettina Strack, Arianna Calistri, Stewart Craig, Elena Popova, Heinrich G. Gottlinger | |||
| A JNK-dependent pathway is required for TNFalpha-induced apoptosis. | Biological sciences | Yibin Deng, Xiaoyang Ren, Lin Yang, Yahong Lin, Xiangwei Wu | |||
| A key role for TRPM7 channels in anoxic neuronal death. | Biological sciences | Michelle Aarts, Koji Lihara, Wen-Li Wei, Zhi-Gang Xiong, Mark Arundine, Waldy Cerwinski, John F. MacDonald, Michael Tymianski | |||
| A kinesin, InvA, plays an essential role in Volvox morphogenesis. | Biological sciences | David L. Kirk, Ichiro Nishi, Satoshi Ogihara | |||
| Alternative tertiary structure of tRNA for recognition by a posttranscriptional modification enzyme. | Biological sciences | Osamu Nureki, Shigeyuki Yokoyama, Ryuichiro Ishitani, Nobukazu Nameki, Norishiro Okada, Susumu Nishimura | |||
| A major step on the road to understanding a unique posttranslational modification and its role in a genetic disease. | Biological sciences | Jacques U. Baeziger | |||
| A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer. | Biological sciences | Todd R. Golub, Mark E. Ewen, Nick Patterson, Justin Lamb, Ramaswamy Sridhar, Heide L. Ford, Bernardo Contreras, Robert V. Martinez, Frances S. Kittrell, Cynthia A. Zahnow | |||
| A molecular throttle: the recombination hotspot chi controls DNA translocation by the RecBCD helicase. | Biological sciences | Stephen C. Kowalczykowski, Piero R. Bianco, Ronald J. Baskin, Maria Spies, Mark S. Dillingham, Naofumi Handa | |||
| A myristoyl/phosphotyrosine switch regulates c-Abl. | Biological sciences | John Kuriyan, Bhushan Nagar, Oliver Hantschel, Sebastian Guettler, Jana Kretzschmar, Karel Dorey, Giulio Superti-Furga | |||
| A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in Aplysia. | Biological sciences | Amit Etkin, Eric R. Kandel, Maurizio Giustetto, Huixiang Zhu, Kausik Si, Ruby Hsu, Agnieszka M. Janisiewicz, Maria Conchetta Miniaci, Joung-Hun Kim | |||
| A neuronal isoform of the Aplysia CPEB has prion-like properties. | Biological sciences | Eric R. Kandel, Kausik Si, Susan Lindquist | |||
| A new role for Ran in ensuring precise duplication of chromosomal DNA.(Brief Article) | Biological sciences | J. Julian Blow | |||
| An intrinsic adenylate kinase activity regulates gating of the ABC transporter CFTR. | Biological sciences | Michael J. Welsh, Christoph Randak | |||
| ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. | Biological sciences | Gina M. Story, Andrea M. Peier, Alison J. Reeve, Samer R. Eid, Johannes Mosbacher, Todd R Hricik, Taryn J. Earley, Anne C. Hergarden, David A. Andersson, Sun Wook Hwang, Peter McIntyre, Tim Jegla, Stuart Bevan, Ardem Patapoutian | |||
| Another tie that binds the MTA family to breast cancer.(metastasis-associated genes) | Biological sciences | Rakeh Kumar | |||
| Anteroposterior patterning in hemichordates and the origins of the chordate nervous system. | Biological sciences | Marc Kirschner, Adrian Salic, Mike Wu, Christopher J. Lowe, Louise Evans, Eric Lander, Nicole Stange-Thomann, Christian E. Gruber, John Gerhart | |||
| A nutrient sensor mechanism controls Drosophila growth. | Biological sciences | Jacques Montagne, Thomas Radimerski, Julien Colombani, Sophie Raisin, Sophine Pantalacci, Pierre Leopold | |||
| A panoramic view of yeast noncoding RNA processing. | Biological sciences | Gerard Cagney, Timothy R. Hughes, Wen-Tao Peng, Mark D. Robinson, Sanie Mnaimneh, Nevan J. Krogan, Quaid Morris, Armaity P. Davierwala, Jorg Grigull, Xueqi Yang, Wen Zhang, Nicholas Mitsakakis, Owen W. Ryan, Nira Datta, Vladimir Jojic, Chris Pal, Veronica Canadien, Dawn Richards, Bryan Beattie, Lani F. Wu, Steven J. Altschuler, Sam Roweis, Brendan J. Frey, Andrew Emili, Jack F. Greenblatt | |||
| A pathway for association of receptors, adaptors, and actin during endocytic internalization. | Biological sciences | Marko Kaksonen, David G. Drubin, Yidi Sun | |||
| Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pl asymmetric divisions. | Biological sciences | William Chia, Yu Cai, Fengwei Yu, Shuping Lin, Xiaohang Yang | |||
| Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. | Biological sciences | Gernot Stuhler, Kirsten Lauber, Erwin Bohn, Stefan Martin Krober, Yi-jin Xiao, Sibylle G. Blumenthal, Ralph K. Lindemann, Patrizia Marini, Carolin Wiedlg, Anke Zobywalski, Shairaz Bakshi, Yan Xu, Ingo B. Autenrieth, Klaus Schulze-Osthoff, Claus Belka, Sebastian Wesselborg | |||
| Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. | Biological sciences | C. David Allis, Peter Cheung, Wang L. Cheung, Kozo Ajiro, Kumiko Samejima, Malgorzata Kloc, Craig A. Mizzen, Alexander Beeser, Laurence D. Etkin, Jonathan Chernoff, William C. Earnshaw | |||
| A Rad53 kinase-dependent surveillance mechanism 3that regulates histone protein levels6 in S. cerevisiae. | Biological sciences | Akash Gunjan, Alain Verreault | |||
| Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage. | Biological sciences | Hubert Kettenberger, Karim-Jean Armache, Patrick Cramer | |||
| Are ubiquitination pathways central to Parkinson's disease?.(Review) | Biological sciences | Virginia M.-Y. Lee, Benoit I. Giasson | |||
| A role for Ran-GTP and Crm1 in blocking re-replication. | Biological sciences | Ryuji Yamaguchi, John Newport | |||
| A somatic compartment of tendon progenitors. | Biological sciences | Clifford J. Tabin, Ava E. Brent, Ronen Schweitzer | |||
| A stimulatory role for cGMP-dependent protein kinase in platelet activation. | Biological sciences | Franz Hofmann, Robert Feil, Zhenyu Li, Xiaodong Xi, Minyi Gu, Richard D. Ye, Martin Eigenthaler, Xiaoping Du | |||
| A stress sensor for the bacterial periplasm.(Brief Article) | Biological sciences | F. Ulrich Hartl, Jason C Young | |||
| Asymmetry in the assembly of the RNAi enzyme complex.(RNA interference) | Biological sciences | Phillip D. Zamore, Dianne S. Schwarz, Gyorgy Hutvagner, Tingting Du, Zuoshang Xu, Neil Aronin | |||
| Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. | Biological sciences | Toru Hirota, Naoko Kunitoku, Takashi Sasayama, Tomotoshi Marumoto, Dongwei Zhang, Masayuki Nitta, Katsuyoshi Hatakeyama, Hideyuki Saya | |||
| Axonal ephrin-as and odorant receptors: coordinate determination of the olfactory sensory map. | Biological sciences | Richard Axel, Adriana Nemes, Jonas Frisen, Tyler Cutforth, Laurie Moring, Monica Mendelsohn, Nirao M. Shah, Michelle M. Kim | |||
| bantam Encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. | Biological sciences | Stephen M. Cohen, Julius Brennecke, David R. Hipfner, Alexander Stark, Robert B. Russell | |||
| BMP induction if Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. | Biological sciences | Austin Smith, Ian Chambers, Jennifer Nichols, Qi-Long Ying | |||
| By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation. | Biological sciences | Peter M. Henson, Shyra J. Gardai, Yi-Qun Xiao, Matthew Dickinson, Jerry A. Nick, Dennis R. Voelker, Kelly E. Greene | |||
| CCR5 mimicry by sulfated human anti-HIV-1 antibodies. | Biological sciences | George Lin, James A. Hoxie | |||
| Cell cycle regulated transport controlled by alterations in the nuclear pore complex. | Biological sciences | Taras Makhnevych, C. Patrick Lusk, Andrea M. Anderson, John D. Aitchison, Richard W. Woznialk | |||
| Chordate evolution in a new light. | Biological sciences | Diethard Tautz | |||
| Chromosomal cohesin forms a ring. | Biological sciences | Kim Nasmyth, Stephan Gruber, Christian H. Haering | |||
| Churchill, a zinc finger transcriptional activator regulates the transition between gasrulation and neurulation. | Biological sciences | Claudio D. Stern, Guojun Sheng, Mario Dos Reis | |||
| Closing another gap in the plant SAR puzzle.(systemic acquired resistance) | Biological sciences | Imre E. Somssich | |||
| Closing the folding chamber of the eukaryotic chaperonin requires the transition state of ATP hydrolysis. | Biological sciences | Sebastian Doniach, Dirk Walther, Anne S. Meyer, Joel R. Gillespie, Ian S. Millet, Judith Frydman | |||
| Communication by touch: role of cellular extensions in complex animals.(Minireview) | Biological sciences | Pernille Rorth | |||
| Computational modeling and experimental analysis of nonsense-mediated decay in yeast. | Biological sciences | Roy Parker, Dan Cao | |||
| Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin. | Biological sciences | Hiten D. Madhani, Marc D. Meneghini, Michelle Wu | |||
| Control of cell morphogenesis in bacteria: two distinct ways to make a rod-shaped cell. | Biological sciences | Richard A. Daniel, Jeff Errington | |||
| Control of myoblast fusion by a guanine nucleotide exchange factor, loner, and its effector ARF6. | Biological sciences | Eric N. Olson, Elizabeth H. Chen, Brian A. Pryce, Jarvis A. Tzeng, Guillermo A. Gonzalez | |||
| Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient.(Decapentaplegic) | Biological sciences | Konrad Basler, Bruno Muller, Britta Hartmann, George Ryrowolakis, Markus Affolter | |||
| Coordinate regulation of an extended chromosome domain. | Biological sciences | Michael Levine, Vincent C. Calhoun | |||
| COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases.(Review) | Biological sciences | Gregory A. Cope, Raymond J. Deshales | |||
| Cryptochromes: enabling plants and animals to determine circadian time.(Review) | Biological sciences | Anthony R. Cashmore | |||
| Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport. | Biological sciences | Gerwald Jogl, Liang Tong | |||
| Cyclin E ablation in the mouse. | Biological sciences | Roderick T. Bronson, Piotr Sicinski, Yan Geng, Qunyan Yu, Ewa Sicinska, Manjusri Das, Jurgen E. Schneider, Shoumo Bhattacharya, william M. III Rideout, Humphrey Gardner | |||
| Death by deamination: a novel host restriction system for HIV-1.(Minireview) | Biological sciences | Stephen P. Goff | |||
| Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired Pemphigus vulgaris. | Biological sciences | John P. Sundberg, Jouni Uitto, Jurg Ott, David Whiting, Ana Kljuic, Hisham Bazzi, Amalia Matrinez-Mir, Ryan O'Shaughnessy, My G. Mahoney, Moise Levy, Xavier Montagutelli, Wasim Ahmad, Vincent M. Aita, Derek Gordon, Stuart Fischer, T. Conrad Gilliam, Colin A. B. Jahoda, Rebecca J. Morris, Andrei A. Panteleyev, Vu Thuong Nguyen, Angela M. Christiano | |||
| Developmentally programmed gene elimination in Euplotes crassus facilitates a switch in the telomerase catalytic subunit. | Biological sciences | Zemfira Karamysheva, Libin Wang, Timothy Shrode, Janna Bednenko, Leigh Anne Hurley, Dorothy E. Shippen | |||
| Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli. | Biological sciences | Mariette R. Atkinson, Michael A. Savageau, Jesse T. Myers, Alexander J. Ninfa | |||
| Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells. | Biological sciences | Michael P. Myers, Takao Ono, Ana Losada, Michiko Hirano, Andrew F. Neuwald, Tatsuya Hirano | |||
| Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23. | Biological sciences | Erwin Neher, Nils Brose, Frederique Varoqueaux, Jakob B. Sorensen, Gabor Nagy, Ralf B. Nehring, Michael C. Wilson | |||
| Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons. | Biological sciences | Yuh Nung Jan, Lily Y. Jan, Wesley B. Grueber | |||
| Directional sensing requires G(beta)(gamma)-mediated PAK1 and PIX(alpha)-dependent activation of Cdc42.(p21-activated kinase )(PAK-associated guanine nucleotide exchange factor ) | Biological sciences | Mingyao Liu, Dianqing Wu, Wei Lu, Zhong Li, Michael Hannigan, Zhicheng Mo, Bo Liu, Yue Wu, Alan V. Smrcka, Guanqing Wu, Lin Li, Chi-Kuang Huang | |||
| Distinct replication requirements for the two Vibrio cholerae chromosomes. | Biological sciences | Matthew K. Waldor, Elizabeth S. Egan | |||
| Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. | Biological sciences | Fei Wang, Henry R. Bourne, Kathleen Kelly, Jingsong Xu, Alexandra van Keymeulen, Paul Herzmark, Aaron Straight, Yoh Takuwa, Naotoshi Sugimoto, Timothy Mitchison | |||
| DNA deamination mediates innate immunity to retroviral infection. | Biological sciences | Michael S. Neuberger, Michael H. Malim, Reuben S. Harris, Kate N. Bishop, Ann M. Sheehy, Heather M. Craig, Svend K. Petersen-Mahrt, Ian N. Watt | |||
| DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis. | Biological sciences | Michael B. Reed, Helena I. M. Boshoff, Clifton E. Barry III, Valerie Mizrahi | |||
| DNA single-strand break repair and spinocerebellar ataxia. | Biological sciences | Keith W. Caldecott | |||
| DOCK4, a GTPase activator, is disrupted during tumorigenesis. | Biological sciences | Daphne W. Bell, Doke C.R. Wahrer, Daniel A. Haber, Paul Reynolds, Vijay Yajnik, Charles Paulding, Raffaella Sordella, Andrea I. McClatchey, Mako Saito, Robert Lake, Sander van den Heuvel, Jeff Settleman | |||
| Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity. | Biological sciences | William E. Theurkauf, Saeko Takada, Anju Kelkar | |||
| Drosophila clock can generate ectopic circadian clocks. | Biological sciences | Patrick Emery, Michael Rosbash, Jie Zhao, Valerie Kilman, Kevin P. Keegan, Ying Peng, Ravi Allada | |||
| Drosophila PAR-1 and 14-3-3 inhibit bazooka/PAR-3 to establish complementary cortical domains in polarized cells. | Biological sciences | Richard Benton, Daniel St. Johnston | |||
| Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing. | Biological sciences | Mauro Anglana, Francoise Apiou, Aaron Bensimon, Michelle Debatisse | |||
| EIN3-dependent regulation of plant ethylene hormone signaling by two Arabidopsis F box proteins: EBF1 and EBF2. | Biological sciences | Csaba Koncz, Thomas Potuschak, Esther Lechner, Yves Parmentier, Shuichi Yanagisawa, Sandrine Grava, Pascal Genschik | |||
| Emerging parallels in the generation and regeneration of skeletal muscle. | Biological sciences | Lauren Snider, Stephen J. Trapscott | |||
| EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. | Biological sciences | Tony Kouzarides, Elena Cattaneo, Chris P. Ponting, David Bentley, Carlos Caldas, Bruce Ponder, Luke Hughes-Davies, David Huntsman, Margarida Ruas, Francois Fuks, Jacqueline Bye, Suet-Feung Chin, Jonathon Milner, Lindsay A. Brown, Forrest Hsu, Blake Gilks, Torsten Nielsen, Michael Schulzer, Stephen Chia, Joseph Ragaz, Anthony Cahn, Lori Linger, Hilal Ozdag, E.S. Jordanova, Edward Schuuring, David S. Yu, Ashok Venkitaraman, Aidan Doherty, Samuel Aparicio, Charles Theillet | |||
| Endocytosis and signaling: a relationship under development.(Meeting Review) | Biological sciences | Marcos Gonzalez-Gaitan, Herald Stenmark | |||
| Endosome-specific localization and function of the ARF activator GNOM.(ADP-Ribosylation Factor) | Biological sciences | Juan S. Bonificino, Catherine L. Jackson | |||
| Energetics of protein transport across biological membranes: a study of the thylakoid (Delta)pH-dependent/cpTat pathway. | Biological sciences | Nathan N. Alder, Steven M. Theg | |||
| Entrapping ribosomes for viral translation: tRNA mimicry as a molecular Trojan hourse. | Biological sciences | Sharief Barends, Hugo H. J. Bink, Sjoerd Worm H. E. van den, Cornelis W. A. Pleij, Barend Kraal | |||
| Essential role of glycosaminoglycans in Fgf signaling during mouse gastrulation. | Biological sciences | Kathryn V. Anderson, Maria J. Garcia-Garcia | |||
| Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. | Biological sciences | Frank Gannon, Raphael Metivier, Graziella Penot, Michael R. Hubner, George Reid, Heike Brand, Martin Kos | |||
| Evolution of a combinatorial . | Biological sciences | Alexander D. Johnson, Annie E. Tsong, Mathew G Miller, Ryan M. Raisner | |||
| Exit from exit: resetting the cell cycle through Amn1 inhibition of G protein signaling. | Biological sciences | Stephen J. Elledge, J. Wade Harper, Dou Liu, Yanchang Wang, Takahiro Shirogane | |||
| Extracellular crosstalk: when GDNF meets N-CAM.(glial cell line-derived neurotrophic factor)(neural cell adhesion molecule) | Biological sciences | William D. Snider, Feng-Quan Zhou, Jian Zhong | |||
| F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. | Biological sciences | Hideyuki Okano, Melitta Schachner, Raphael Kopan, Catherine J. Pallen, Thomas Maciag, Qi-Dong Hu, Beng-Ti Ang, Meliha Karsak, Wei-Ping Hu, Xiao-Ying Cui, Tanya Duka, Yasuo Takeda, Wendy Chia, Natesan Sankar, Deena Small, Radianna Trifonova, Masato Nakafuku, Shigeru Chiba, Hisamaru Hirai, Jon J. Aster, Kazutada Watanabe, Zhi-Cheng Xiao, Yee-Kong Ng, Eng-Ang Ling | |||
| FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death.(FK binding protein) | Biological sciences | Nora Rosemblit, Andrew R. Marks, Silvia G. Priori, Carlo Napolitano, Long-Sheng Song, Xander H. T. Wehrens, Stephan E. Lehnart, Fannie Huang, John A. Vest, Steven R. Reiken, Peter J. Mohler, Jie Sun, Silvia Guatimosim, Jeanine M. D'Armiento, Mirella Memmi, W. J. Lederer | |||
| Formation of an endophilin-Ca(sup)2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis. | Biological sciences | Gong Chen, Yuan Chen, Lunbin Deng, Yuka Maeno-Hikichi, Meizan Lai, Shaohua Chang, Ji-fang Zhang | |||
| From lineage to wiring specificity: POU domain transcription factors control precise connections of Drosophila olfactory projection neurons. | Biological sciences | Takaki Komiyama, Wayne A. Johnson, Liqun Luo, Gregory S. X. E. Jefferis | |||
| Functional expression cloning of nanog, a pluripotency sustaining factor in embryonic stem cells . | Biological sciences | Susan Tweedie, Austin Smith, Ian Chambers, Douglas Colby, Morag Robertson, Jennifer Nichols, Sonia Lee | |||
| Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class lb molecules. | Biological sciences | Catherine Dulac, Jennifer Loconto, Fabio Papes, Ernie Chang, Lisa Stowers, Elsy P. Jones, Toyoyuki Takada, Attila Kumanovics, Kristen Fischer Lindahl | |||
| Functional siRNAs and miRNAs exhibit strands bias. | Biological sciences | Anastasia Khvorova, Angela Reynolds, Sumedha D. Jayasena | |||
| Fusion with the fused: a new role for Interleukin-4 in the building of muscle. | Biological sciences | Michael A. Rudnicki, Sophie Charge | |||
| FY is an RNA 3' end-processing factor that interacts with FCA to control the Arabidopsis floral transition. | Biological sciences | Caroline Dean, Gordon G. Simpson, Paul P. Dijkwel, Victor Quesada, Ian Henderson | |||
| Gene switching by metabolic enzymes- how did you get on the invitation list? | Biological sciences | Steve McKnight | |||
| Global chromosome positions are transmitted through mitosis in mammalian cells. | Biological sciences | Roland Eils, Daniel Gerlich, Joel Beaudouin, Bernd Kalbfuss, Nathalie Daigle, Jan Ellenberg | |||
| Global phage diversity. | Biological sciences | Forest Rohwer | |||
| Graded positional information: interpretation for both fate and guidance. | Biological sciences | Marc W. Kirschner, Miriam Osterfield, John G. Flanagan | |||
| H2AX haploinsufficiency modifies genomic stability and tumor susceptibility. | Biological sciences | Michael J. Difilippantonio, Andre Nussenzweig, Thomas Ried, Arkady Celeste, Oscar Fernandez-Capetillo, Duane R. Pilch, Olga A. Sedelnikova, Michael Eckhaus, William M. Bonner | |||
| HIF-1alpha is essential for myeloid cell-mediated inflammation. | Biological sciences | Randall S. Johnson, Maripat Corr, Napoleone Ferrara, Thorsten Cramer, Nigel Mackman, Gary S. Firestein, Rudolf Jaenisch, Volker H. Haase, Yuji Yamanishi, Bjorn E. Clausen, Irmgard Forster, Rafal Pawlinski, Victor Nizet, Hans-Peter Gerber | |||
| Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. | Biological sciences | Yuh-Nung Jan, Lily Yeh Jan, Song-Hai Shi | |||
| hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with Salvador and Warts. | Biological sciences | Shian Wu, Jianbin Huang, Jixin Dong, Duojia Pan | |||
| Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors. | Biological sciences | David O. Ferguson, Frederick W. Alt, Craig H. Bassing, John Manis, Charles Lee, Heikyung Suh, Katrin F. Chua, Mark Eckersdorff, Megan Gleason, Frederick Bronson | |||
| Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP. | Biological sciences | Richard H. Goodman, Qinghong Zhang, Yasuhiro Yoshimatsu, Jeffrey Hildebrand, Steven M. Frisch | |||
| Homer binds TRPC family channels and is required for gating of TRPC1 by IP(sub)3 receptors. | Biological sciences | Peter H. Seeburg, Kirill Kiselyov, Shmuel Muallem, Jin Chen, Joseph P. Yuan, Dong Ming Shin, Nikolay Shcheynikov, Shin H. Kang, Marlin H. Dehoff, Martin K. Schwarz, Paul F. Worley | |||
| Homothorax switches function of Drosophila photoreceptors from color to polarized light snsors. | Biological sciences | Claude Desplan, Mathias F. Wernet, Thomas Labhart, Franziska Baumann, Esteban O. Mazzoni, Franck Pichaud | |||
| Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics. | Biological sciences | Claudio E. Sunkel, Jason R. Swedlow, William C. Earnshaw, Helder Maiato, Elizabeth A. L. Fairley, Conly L. Reider | |||
| Identification of mouse sperm SED1, a Bimotif EGF repeat and discoidin-domain protein involved in sperm-egg binding. | Biological sciences | Michael A. Ensslin, Barry D. Shur | |||
| IL-4 acts as a myoblast recruitment factor during mammalian muscle growth. | Biological sciences | Valerie Horsley, Katie M. Jansen, Stephen T. Mills, Grace K. Pavlath | |||
| Inducers of plant systematic acquired resistance regulate NPR1 function through redox changes. | Biological sciences | Zhonglin Mou, Weihua Fan, Xinnian Dong | |||
| Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes.(tumor necrosis factor) | Biological sciences | Olivier Micheau, Jurg Tschopp | |||
| Inositol pyrophosphatases mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P(sub)3 interactions. | Biological sciences | Keqiang Ye, Solomon H. Snyder, Hongbo Luo R., Yi Elaine Huang, Jianmeng C. Chen, Adolfo Saiardi, Miho Lijima, Yunfei Huang, Eiichiro Nagata, Peter Devreotes | |||
| Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. | Biological sciences | Eric S. Lander, Nick Patterson, Vamsi K. Mootha, Mathias Mann, Jakob Bunkenborg, Jesper V. Olsen, Majbrit Hjerrild, Jacek R. Wisniewski, Erich Stahl, Marjan S. Bolouri, Heta N. Ray, Smita Sihag, Michael Kamal | |||
| Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinoserebellar ataxia type 1. | Biological sciences | Harry T. Orr, Huda Y. Zoghbi, Pedro Fernandez-Funez, Michael D. Kaytor, Hung-Kai Chen, Summer F. Acevedo, Yung C. Lam, Michael H. Fernandez, Alastair Aitken, Efthimios M. C. Skoulakis, Juan Botas | |||
| Interchangeable parts of the Escherichia coli recombination machinery.(Minireview) | Biological sciences | Gerald R. Smith, Susan K. Amundsen | |||
| In the beginning: lessons from fertilization in mice and worms.(Minireview) | Biological sciences | Melissa K. Jungnickel, Keith A. Sutton, Harvey M. Florman | |||
| Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks. | Biological sciences | Yoshitaka Fujii, Toshifumi Takao, Arthur I. Skoultchi, Akimitsu Konishi, Shigeomi Shimizu, Junko Hirota, Yuhong Fan, Yosuke Matsuoka, Lilin Zhang, Yoshihiro Yoneda | |||
| Ira Herskowitz (1946-2003).(Biography) | Biological sciences | Carol A. Gross, Franklin W. Stahl | |||
| Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. | Biological sciences | Nickoletta Karabetsou, Jane Mellor, Antonin Morillon, Justin O'Sullivan, Nicholas Kent, Nicholas Proudfoot | |||
| Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension. | Biological sciences | Masahide Kikkawa, Nobutaka Hirokawa, Yosuke Tanaka, Sumio Terada, Takao Nakata, Yosuke Takei, Noriko Homma, Yasuko Noda | |||
| Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA(sup)+ degradation machine. | Biological sciences | Julio M. Fernandez, Robert T. Sauer, Tania A. Baker, Jon A. Kenniston | |||
| Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads. | Biological sciences | Michelangelo Cordenonsi, Sirio Dupont, Silvia Maretto, Alessandra Insinga, Carol Imbriano, Stefano Piccolo | |||
| Lipid rafts: elusive or illusive?.(Review) | Biological sciences | Sean Munro | |||
| Liver tumor development: c-Jun antagonizes the proapoptotic activity of p53. | Biological sciences | Erwin F. Wagner, Jean-Pierre David, Robert Eferl, Romeo Ricci, Lukas Kenner, Rainer Zenz, Martina Rath | |||
| Loading Rho to terminate transcription. | Biological sciences | John P. Richardson | |||
| Local, efflux-dependent auxin gradients as a common module for plant organ formation. | Biological sciences | Gerd Jurgens, Jiri Frimi, Eva Benkova, Marta Michniewicz, Michael Sauer, Thomas Teichmann, Daniela Seifertova | |||
| Locking and unlocking of ribosomal motions. | Biological sciences | Joachim Frank, Mans Ehrenberg, Jayati Sengupta, Mikel Valle, Andrey Zavialov, Urmila Rawat | |||
| Mechanism of ubiquitin recognition by the CUE domain of Vps9p. | Biological sciences | James H. Hurley, Saurav Misra, Rodolfo Ghirlando, Gali Prag, Eudora A. Jones, Brian A. Davies, Bruce F. Horazdovsky | |||
| Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL. | Biological sciences | George Q. Daley, Mohammad Azam, Robert R. Latek | |||
| Mechanisms of TGF-beta signaling from cell membrane to the nucleus. | Biological sciences | Joan Massague, Yigong Shi | |||
| Membranes, trafficking, and signaling during animal development.(Meeting Review) | Biological sciences | Jean-Paul Vincent | |||
| Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix. | Biological sciences | Stephen J. Weiss, Kevin B. Hotary, Edward D. allen, Peter C. Brooks, Nabanita S. Datta, Michael W. Long | |||
| Metastatic potential: generic predisposition of the primary tumor or rare, metastatic variants- or both? | Biological sciences | Richard O. Hynes | |||
| MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing.(Minireview) | Biological sciences | Victor Ambros | |||
| Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation. | Biological sciences | Shan Wu, Yizeng Tu, Xiaohua Shi, Ka Chen, Chuanyue Wu | |||
| Modulation of Rho GTPase signaling regulates a switch between adipogenessis and myogenesis. | Biological sciences | Jeffrey Settleman, Raffaella Sordella, Marcello Curto, Wei Jiang, Guang-Chao Chen | |||
| Molecular basis of phosphorylation-induced activation of the NADPH oxidase. | Biological sciences | Yvonne Groemping, Karine Lapouge, Stephen J. Smerdon, Katrin Rittinger | |||
| Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70. | Biological sciences | F. Ulrich Hartl, Jason C. Young, Nicholas J. Hoogenraad | |||
| MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. | Biological sciences | Naoyuki Fujita, David L. Jaye, Masahiro Kajita, Cissy Geigerman, Carlos S. Moreno, Paul A. Wade | |||
| Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. | Biological sciences | Lelio Orci, Randy Schekman, Elizabeth A. Miller, Traude H. Beilharz, Per N. Malkus, Marcus C.S. Lee, Susan Hamamoto | |||
| Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C (sub)alpha -formylglycine generating enzyme. | Biological sciences | Bernhard Schmidt, Thomas Dierks, Ljudmila V. Borissenko, Jianhe Peng, Andrea Preusser, Malaiyalam Mariappan, Kurt von Figura | |||
| Multiple tumor suppressor pathways negatively regulate telomerase. | Biological sciences | Stephen J. Elledge, Shiaw-Yih Lin | |||
| Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). | Biological sciences | Alain Fischer, Stephane Blanche, Graca Raposo, Isabelle Callebaut, Jerome Feldmann, Stephanie certain, Delphine Bacq, Cecile Dumont, Nathalie Lambert, Marie Ouachee-Chardin, Gaelle Chedeville, Hannah Tamary, Veronique Minard-Colin, Etienne Vilmer, Francoise Le Deist, Genevieve de Saint Basile | |||
| Muscle or fat? Rho bridges of GAP. | Biological sciences | Alan R. Saltiel | |||
| Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors. | Biological sciences | Patrick Lemaire, Vincent Bertrand, Clare Hudson, Danielle Caillol, Cornel Popovici | |||
| Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. | Biological sciences | Marc Tessier-Lavigne, Isabella A. Graef, Lei Chen, Gerald R. Crabtree, Frederic Charron, Fan Wang, Joel Neilson | |||
| Neutrophil elastase cleaves PML-RARalpha and is important for the development of acute promyelocytic leukemia in mice. | Biological sciences | Andrew A. Lane, Timothy J. Levy | |||
| Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor. | Biological sciences | Denisa D. Wagner, Kenji Matsushita, Craig N. Morrell, Beatrice Cambien, Shui-Xiang Yang, Munekazu Yamakuchi, Clare Bao, Makoto R. Hara, Richard A. Quick, Wangsen Cao, Brian O'Rourke, John M. Lowenstein, Jonathan Pevsner, Charles J. Lowenstein | |||
| Nuclear receptors: a rendezvous for chromatin remodeling factors.(Minireview) | Biological sciences | Malcolm G. Parker, Borja Belandia | |||
| Obituary.(Charles A. Janeway, Jr. (1943-2003))(Obituary) | Biological sciences | Jordan S. Pober, Richard A. Flavell, David G. Schatz, Peter Cresswell, Kim Bottomly, Sankar Ghosh | |||
| O-GlcNAc modification is an endogenous inhibitor of the proteasome. | Biological sciences | Fengxue Zhang, Kaihong Su, Xiaoyong Yang, Damon B. Bowe, Andrew J. Paterson, Jeffrey E. Kudlow | |||
| OMP peptide signals initiate the envelope-stress response by activating DegS protease via relief of inhibition mediated by its PDZ domain. | Biological sciences | Carol A. Gross, Robert T. Sauer, Nathan P. Walsh, Benjamin M. Alba, Baundauna Bose | |||
| Origins of highly mosaic mycobacteriophage genomes. | Biological sciences | Roger W. Hendrix, William R. Jacobs Jr., John A. Lewis, Jeffrey G. Lawrence, Marisa L. Pedulla, Michael E. Ford, Jennifer M. Houtz, Tharun Karthikeyan, Curtis Wadsworth, Debbie Jacobs-Sera, Joseph Gross, Nicholas R. Pannunzio, William Brucker, Vanaja Kumar, Jayasankar Kandasamy, Lauren Keenan, Svetsoslav Bardarov, Jordan Kriakov, Graham F. Hatfull, Jacob Falbo | |||
| p53 and TGF-beta in development: prelude to tumor suppression? | Biological sciences | Frank McKeon, Malcolm Whitman | |||
| painless, A Drosophila gene essential for nociception. | Biological sciences | Gilles Laurent, Rachel I. Wilson, W. Daniel Tracey Jr., Saymour Benzer | |||
| Parc: a cytoplasmic anchor for p53. | Biological sciences | Jun Qin, Wei Gu, Anatoly Y. Nikolaev, Muyang Li, Norbert Puskas | |||
| Parc-ing p53 in the cytoplasm. | Biological sciences | Michael B. Kastan, Gerard P. Zambetti | |||
| PARP goes transcription.(Review) | Biological sciences | John T. Lis, W. Lee Kraus | |||
| Pars, PI 3-kinase and the establishment of neuronal polarity. | Biological sciences | Gary Banker | |||
| Peptidyl-tRNA regulates the GTPase activity of translation factors. | Biological sciences | Mans Ehrenberg, Andrey V. Zavialov | |||
| Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. | Biological sciences | Ronald M. Evans, Yong Xu Wang, Chih-Hao Lee, Sambath Tiep, Ruth T. Yu, Jungyeob Ham, Heonjoong Kang | |||
| Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. | Biological sciences | Tomas Kirchhausen, Jing Wang, Manuel Martinez, Ying Jie Wang, Hui Qiao Sun, Yu Xiao Sun, Eric Macia, Joseph P. Albanesi, Michael G. Roth, Helen L. Yin | |||
| Phosphorylation of RIM1alpha by PKA triggers presynaptic long-term potentiation at cerebellar parallel fiber synapses. | Biological sciences | Thomas C. Sudhof, Pascal S. Kaeser, Gyorgy Lonart, Susanne Schoch, C. Jenny Larkin, David J. Linden | |||
| Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory. | Biological sciences | Hey-Kyoung Lee, Richard L. Huganir, Kogo Takamiya, Jung-Soo Han, Hengye Man, Chong-Hyun Kim, Gavin Rumbaugh, Sandy Yu, Lin Ding, Chun He, Ronald S. Petralia, Robert L. wenthold, Michela Gallagher | |||
| Pirh2, a p-53-induced ubiquitin-protein ligase, promotes p53 degradation. | Biological sciences | Guillermina Lozano, Hong Wu, Razqallah Hakem, Roger P. Leng, Yunping Lin, Weili Ma, Benedicte Lemmers, Stephen Chung, John M. Parant, Samuel Benchimol | |||
| Plant responses to ethylene gas are mediated by SCF(sup)EBF1/EBF2 -dependent proteolysis of EIN3 transcription factor. | Biological sciences | Joseph R. Ecker, Hongwei Guo | |||
| Plasmodium biology: genomic gleanings. | Biological sciences | Louis H. Miller, L. Aravind, Thomas E. Wellems, Lakshminarayan M. Iyer | |||
| Pollen tube growth and guidance is regulated by POP2, an Arabidopsis gene that controls GABA levels. | Biological sciences | Ravishankar Palanivelu, Laura Brass, Anna F. Edlund, Daphne Preuss | |||
| Polycomb, epigenomes, and control of cell identity.(Review) | Biological sciences | Valerio Orlando | |||
| Prediction of mammalian microRNA targets. | Biological sciences | David P. Bartel, Christopher B. Burge, Benjamin P. Lewis, I-hung Shih, Matthew W. Jones-Rhoades | |||
| Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling.(mitogen-activated protein kinase) | Biological sciences | Richard A. Young, Gerald R. Fink, Itamar Simon, Christopher T. Harbison, Thomas L. Volkert, Julia Zeitlinger, Nancy M. Hannett | |||
| Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation. | Biological sciences | Michele Pagano, Virginia Amador, Joanna Bloom, Francesca Bartolini, George DeMartino | |||
| R2D2 leads the silencing trigger to mRNA's death star. | Biological sciences | Janice L. Pellino, Erik J. Sontheimer | |||
| Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. | Biological sciences | Gregory J. Hannon, Edith Heard, David L. Spector, Masashi Narita, Sabrina Nunez, Masako Narita, Athena W. Lin, Stephen A. Hearn, Scott L. Lowe | |||
| "Recruitment signals" from apoptotic cells: invitation to a quiet meal. | Biological sciences | Kodi S. Ravichandran | |||
| Regeneration: if they can do it, why can't we?.(Minireview) | Biological sciences | Elly M. Tanaka | |||
| Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translation control. | Biological sciences | Barsanjit Mazumder, Prabha Sampath, Vasudevan Seshadri, Ratan K. Maitra, Paul E. Dicorleto, Paul L. Fox | |||
| Regulating the regulators: lysine modifications make their mark. | Biological sciences | Robert Tjian, Richard N. Freiman | |||
| Regulation of vertebrate cellular Mg (super)2+ homeostasis by TRPM7. | Biological sciences | Andrea Fleig, Reinhold Penner, Kazunori Inabe, Anne-Laure Perraud, Tomohiro Kurosaki, Carsten Schmitz, Catherine O. Johnson, Megan K. Smith, Andrew M. Scharenberg | |||
| Release of ubiquitin-charged Cdc34-S(squiggle)Ub from the RING domain is essential for ubiquitination of the SCF(sup)Cdc4-bound substrate Sic1. | Biological sciences | Andrew E. Deffenbaugh, K. Matthew Scaglione, Lingxiao Zhang, Johnnie M. Moore, Tione Buranda, Larry A. Sklar, Dorota Skowyra | |||
| Reverse transcriptase of moloney murine leukemia virus binds to eukaryotic release factor 1 to modulate suppression of translational termination. | Biological sciences | Andrew Yueh, Stephen P. Goff, Marianna Orlova, Juliana Leung | |||
| Ribosome loading onto the mRNA cap is driven by conformational coupling between elF4G and elF4E. | Biological sciences | Alan B. Sachs, Gerhard Wagner, Alexey A. Lugovskoy, John D. Gross, Nathan J. Moerke, Tobias von der Haar, John E.G. McCarthy | |||
| Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria. | Biological sciences | Maumita Mandal, Benjamin Boese, Jeffrey E. Barrick, Wade C. Winkler, Ronald R. Breaker | |||
| RraA: a protein inhibitor of RNase E activity that globally modulates RNA abundance in E. coli. | Biological sciences | Stanley N. Cohen, George Georgiou, Kangseok Lee, Xiaoming Zhan, Junjun Gao, Ji Qiu, Yanan Feng, R. Meganathan | |||
| Schizosaccharomyces pombe Int6 and Ras homologs regulate cell division and mitotic fidelity via the proteasome. | Biological sciences | Eric C. Chang, Hsueh-Chi S. Yen, Colin Gordon | |||
| Sensing stretch is fundamental. | Biological sciences | Julien S. Davis, Neal D. Epstein | |||
| Sequential modification of NEMO/IKK(sub)gamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. | Biological sciences | Tony T. Huang, Shelly M. Wuerzberger-Davis, Zhao-Hui Wu, Shigeki Miyamoto | |||
| Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. | Biological sciences | Zhigang Xie, Kamon Sanada, Benjamin Adam Samuels, Heather Shih, Li-Huei Tsai | |||
| Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. | Biological sciences | Diego J. Walther, Jens-Uwe Peter, Sandra Winter, Markus Hoitje, Nils Paulmann, Maik Grohmann, Jakob Vowinckel, Victor Alamo-Bethencourt, Claudia S. Wilhelm, Gudrun Ahnert-Hilger, Michael Bader | |||
| SET-ting the stage for life and death.(Preview) | Biological sciences | Debabrata Chakravarti, Rui Hong | |||
| Size selective recognition of siRNA by an RNA silencing suppressor. | Biological sciences | Jeffrey M. Vargason, Gyorgy Szittya, Jozsef Burgyan, Traci Tanaka Hall | |||
| SNARE selectivity of the COPII coat. | Biological sciences | Jonathan Goldberg, Elena Mossessova, Lincoln C. Bickford | |||
| S-nitrosylation of NSF controls membrane trafficking. | Biological sciences | Thomas H. Sollner, Sonia Sequeira | |||
| Soluble dimeric prion protein binds PrP(sup)Sc in vivo and antagonizes prion disease. | Biological sciences | Adriano Aguzzi, Marco Prinz, Philipp Meier, Nicolas Genoud, Manuela Maissen, Thomas Rulicke, Andreas Zurbriggen, Alex J. Raeber | |||
| Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding. | Biological sciences | Ishwar Radhakrishnan, Linda Hicke, Richard S. Kang, Cynthia M. Daniels, Smitha A. Francis, Susan C. Shih, William J. Salerno | |||
| Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. | Biological sciences | Francisco Navarro, Roberto Mariani, Darlene Chen, Barbel Schrofelbauer, Renate Konig, Brooke Bollman, Carsten Munk, Hanrietta Nymark-McMahon, Nathaniel R. Landau | |||
| Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code. | Biological sciences | Douglas W. Allan, Susan E. St. Pierre, Irene Miguel-Aliaga, Stefan Thor | |||
| S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.(Oct-1 coactivator)(glyceraldehyde-3-phosphate dehydrogenase) | Biological sciences | Robert G. Roeder, Lei Zheng, Yan Luo | |||
| Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. | Biological sciences | Anna Malkova, James E. Haber, Giordano Liberi, Marco Foiani, Grzegorz Ira | |||
| Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family. | Biological sciences | Marc Tessier-Lavigne, Anil Bagri, Hwai-Jong Cheng, Avraham Yaron, Samuel J. Pleasure, hippocampal | |||
| Structural basis for phosphodependent substrate selection and orientation by SCF (super)Cdc4 ubiquitin ligase.(SCF= Skp1-Cdc53/Cullin-F box protein) | Biological sciences | Mike Tyers, Frank Sicheri, Stephen Orlicky, Xiaojing Tang, Andrew Willems | |||
| Structural basis for the autoinhibition of c-Abl tyrosine kinase. | Biological sciences | John Kuriyan, Bayard Clarkson, Bhushan Nagar, Oliver Hantschel, Giulio Superti-Furga, Matthew A. Young, Klaus Scheffzek, Darren Veach, Williams Bornmann | |||
| Structural basis for the function of the beta subunit of the eukaryotic signal recognition particle receptor. | Biological sciences | Gunter Blobel, Thomas Schwartz | |||
| Structural basis of core promoter recognition in a primitive eukaryote. | Biological sciences | Maria A. Schumacher, Audrey O.T. Lau, Patricia J. Johnson | |||
| Structural evidence for feedback activation by Ras-GTP of the Ras-specific nucleotide exchange factor SOS. | Biological sciences | Dafna Bar-Sagi, John Kuriyan, S. Mariana Margarit, Holger Sondermann, Brian E. Hall, Bhushan Nagar, Andre Hoelz, Michelle Pirruccello | |||
| Structure and biogenesis of the capsular F1 antigen from Yersinia pestis: preserved folding energy drives fiber formation. | Biological sciences | Anton V. Zavialov, Jenny Berglund, Alexander F. Pudney, Laura J. Fooks, Tara M. Ibrahim, Sheila Maclntyre, Stefan D. Knight | |||
| Structure and function of the transcription elongation factor GreB bound to bacterial RNA polymerase. | Biological sciences | Natacha Opalka, Mark Chlenov, Pablo Chacon, William J. Rice, Willy Wriggers, Seth A. Darst | |||
| Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase. | Biological sciences | Qin Feng, Jinrong Min, Rui-Ming Xu, Zhizhong Li, Yi zhang | |||
| Structure of the mammalian mitochondrial ribosome reveals an expanded functional role for its component proteins. | Biological sciences | Rajendra K. Agrawal, Manjuli R. Sharma, Emine C. Koc, Partha P. Datta, Timothy M. Booth, Linda L. Spremulli | |||
| Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading. | Biological sciences | James M. Berger, Emmanuel Skordalakes | |||
| Structures of the alphaL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation. | Biological sciences | Junichi Takagi, Timothy A. Springer, Motomu Shimaoka, Tsan Xiao, Jin-Huan Liu, Yuting Yang, Yicheng Dong, Chang-Duk Jun, Alison McCormack, Rongguang Zhang, Andrzej Joachimiak, Jia-Huai Wang | |||
| Study of the structural dynamics of the E. coli 70S ribosome using real-space refinement. | Biological sciences | Rajendra K. Agrawal, Andrej Sali, Jayati Sengupta, Mikel Valle, Haixiao Gao, Andrei Korostelev, Eswar Narayanan, Scott M. Stagg, Patrick Van Roey, Stephen C. Harvey, Michael S. Chapman | |||
| Switch-of-function mutants based on morphology classification of Ras superfamily small GTPases. | Biological sciences | Tobias Meyer, Won Do Heo | |||
| Symmetry, selectivity, and the 2003 Nobel Prize.(Essay) | Biological sciences | David E. Clapham | |||
| Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylation. | Biological sciences | Danny Reinberg, Michael Hampsey | |||
| Targeting survival: integration site selection by retroviruses and LTR-retrotransposons.(long terminal repeat) | Biological sciences | Frederic D. Bushman | |||
| Taspase1: threonine aspartase required for cleavage of MLL and proper HOX gene expression. | Biological sciences | Stanley J. Korsmeyer, James J.-D. Hsieh, Emily H.-Y. Cheng | |||
| TB or not TB: how Mycobacterium tuberculosis may evade drug treatment. | Biological sciences | Errol C. Friedberg, Paula L. Fishhaber | |||
| Telomerase maintains telomere structure in normal human cells. | Biological sciences | Robert A. Weinberg, William C. Hahn, Mary W. Brooks, Kenkichi Masutomi, Evan Y. Yu, Shilagardy Khurts, Ittai Ben-Porath, Jennifer L. Currier, Geoffrey B. Metz, Shuichi Kaneko, Seishi Murakami, James A. DeCaprio, Sheila A. Stewart | |||
| Temporal regulation of Salmonella virulence effector function by proteasome-dependent protein degradation. | Biological sciences | Jorge E. Galan, Tomoko Kubori | |||
| The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis. | Biological sciences | Kan Cao, Reiko Nakajima, Hemmo H. Meyer, Yixian Zheng | |||
| The Arabidopsis GNOM ARF-GEF mediates endosomal recycling, auxin transport, and auxin-dependent plant growth. | Biological sciences | Gerd Jurgens, Niko Geldner, Nadine Anders, Hanno Wolters, Jutta Keicher, Wolfgang Kornberger, Philippe Muller, Alaine Delbarre, Takashi Ueda, Akihiko Nakano | |||
| The ATRs, ATMs, and TORs are giant HEAT repeat proteins.(ATR= ATM and Rad3 related)(ATM= ataxia telangiectasia mutated)(TOR= target of rapamycin)(HEAT= huntingtin, elongation factor 3, A subunit of protein phosphatase 2A and TOR1) | Biological sciences | Nancy Kleckner, Jason Perry | |||
| The bacterial cytoskeleton: an intermediate filament-like function in cell shape. | Biological sciences | Nora Ausmees, Jeffrey R. Kuhn, Christine Jacobs-Wagner | |||
| The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. | Biological sciences | Mans Ehrenberg, Andrey V. Zavialov, Kim Pedersen, Michael Yu. Pavlov, Johan Elf, Kenn Gerdes | |||
| The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.(brain-derived neurotrophic factor) | Biological sciences | Daniel R. Weinberger, David Goldman, Terry E. Goldberg, Michael Dean, Michael F. Egan, Masami Kojima, Joseph H. Callicott, Bhaskar S. Kolachana, Alessandro Bertolino, Eugene Zaitsev, Bert Gold, Bai Lu | |||
| The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus. | Biological sciences | Julie Ahringer, John G. White, Christian J. Malone, Lisa Misner, Nathalie Le Bot, Miao-Chih Tsai, Jay M. Campbell | |||
| The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.(WINAC: human multiprotein complex) | Biological sciences | Takashi Ito, Takeya Nakagawa, Shigeaki Kato, Hiromichi Nagasawa, Toshio Matsumoto, Hirochika Kitagawa, Ryoji Fujiki, Kimihiro Yoshimura, Yoshihiro Mezaki, Yoshikatsu Uematsu, Daisuke Matsui, Satoko Ogawa, Kiyoe Unno, Mataichi Okubo, Akifumi Tokita, Yukio Ishimi, Junn Yanagisawa | |||
| The clearance mechanism of chilled blood platelets. | Biological sciences | Thomas P. Stossel, Karin M. Hoffmeister, Thomas W. Felbinger, Herve Falet, Cecile V. Denis, Wolfgang Bergmeier, Tanya N. Mayadas, Ulrich H. von Anrdian, Denisa D. Wagner, John H. Hartwig | |||
| The conserved Nup107-160 complex is critical for nuclear pore complex assembly. | Biological sciences | Vincent Galy, Valerie Doye, Matthias Wilm, Iain W. Mattaj, Terry Allen, Tobias C. Walther, Annabelle Alves, Helen Pickersgill, Isabelle Loiodice, Martin Hetzer, Bastian B. Hulsmann, Thomas Kocher | |||
| The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. | Biological sciences | Tso-Pang Yao, Jeffery M. Vance, Yoshiharu Kawaguchi, Jeffrey J. Kovacs, Adam McLaurin, Akihiro Ito | |||
| The double life of ribosomal proteins. | Biological sciences | Robert A. Zimmermann | |||
| The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. | Biological sciences | Cathie M. Pfleger, Iswar K. Hariharan, Kieran F. Harvey | |||
| The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway. | Biological sciences | Millard H. Lambert, David J. Mangelsdorf, Keith D. Baker, Lisa M. Shewchuk, Tatiana Kozlova, Makoto Makishima, Annie Hassell, Bruce Wisely, Justin A. Caravella, Jeffrey L. Reinking, Henry Krause, Carl S. Thummel, Timothy M. Willson | |||
| The gene csd is the primary signal for sexual development in the honeybee and encodes an SR-type protein. | Biological sciences | Martin Beye, Martin Hasselmann, M. Kim Fondrk, Robert E. Jr. Page, Stig W. Omholt | |||
| The histone minority report: the variant shall not be silenced.(Preview) | Biological sciences | Fred van Leeuwen, Daniel E. Gottschling | |||
| The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. | Biological sciences | Kaoru Mitsui, Yoshimi Tokuzawa, Hiroaki Itoh, Kohichi Segawa, Mirei Murakami, Kazutoshi Takahashi, Masayoshi Maruyama, Mitsuyo Maeda, Shinya Yamanaka | |||
| The human Y chromosome: rumors of its death have been greatly exaggerated. | Biological sciences | R. Scott Hawley | |||
| The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar purkinje cells. | Biological sciences | Eric R. Kandel, Bina Santoro, Steven A. Siegelbaum, Gael Malleret, Matthew F. Nolan, Ka Hung Lee, Emma Gibbs, Joshua T. Dudman, Deqi Yin, Richard F. Thompson, Alexel Morozov | |||
| The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans. | Biological sciences | Kang Shen, Cornelia I. Bargmann | |||
| The molecular basis for phosphodependent substrate targeting and regulation of PIks by the Polo-box domain. | Biological sciences | Michael B. Yaffe, Lewis C. Cantley, Stephen J. Smerdon, Andrew E.H. Elia, Peter Rellos, Lesley F. Haire, Jerry W. Chao, Frank J. Ivins, Katja Hoepker, Duaa Mohammad | |||
| The morphogen Sonic hedgehog is an axonal chemoattractant that collaborates with Netrin-1 in midline axon guidance. | Biological sciences | Marc Tessier-Lavigne, Andrew P. McMahon, Juhee Jeong, Frederic Charron, Elke Stein | |||
| The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. | Biological sciences | Markus Grompe, Andrea Ballabio, Maria Pia Cosma, Stefano Pepe, Ida Annunziata, Robert F. Newbold, Giancarlo Parenti | |||
| The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands.(glial cell line-derived neurotrophic factor) | Biological sciences | Carlos F. Ibanez, Gustavo Paratcha, Fernanda Ledda | |||
| The pathogen-inducible nitric oxide synthase (iNOS) in plants is a variant of the P proteins of the glycine decarboxylase complex. | Biological sciences | Daniel F. Klessig, Meena R. Chandok, A. Jimmy Ytterberg, Klaas J. Van Wijk | |||
| The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. | Biological sciences | Zhu Hong, Junying Yuan, David G. Myszka, David R. Jones, Gerhard Wagner, Lewis C. Cantley, Joan S. Brugge, Or Gozani, Philip Karuman, Dmitri Ivanov, James Cha, Alexey A. Lugovskoy, Cheryl L. Baird, Seth J. Field, Stephen L. Lessnick, Jennifer Villasenor, Bharat Mehrotra, Jian Chen, Vikram R. Rao, Colin G. Ferguson, Bernard Payrastre, Nullin Divecha, Glenn D. Prestwich | |||
| The polycomb protein Pc2 is a SUMO E3. | Biological sciences | Michael H. Kagey, Tiffany A. Melhuish, David Wotton | |||
| The protein network of HIV budding. | Biological sciences | Jerry Kaplan, Daniel M. Cimbora, Wesley I. Sundquist, Scott G. Morham, Hubert E. Wang, Uta K. von Schwedler, Melissa Stuchell, Barbara Muller, Diane M. Ward, Hyo-Young Chung, Eiji Morita, Thaylon Davis, Gong-Ping He, Anna Scott, Hans-Georg Krausslich | |||
| The receptors for mammalian sweet and umami taste. | Biological sciences | Nicholas J.P. Ryba, Charles S. Zuker, Yifeng Zhang, Grace Q. Zhao, Isolde Erlenbach | |||
| The stem cell concept in plants: a matter of debate. | Biological sciences | Thomas Laux | |||
| The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. | Biological sciences | Masasuke Yoshida, Paul B. Sigler, Sukyeong Lee, Mathew E. Sowa, Yo-hei Watanabe, Wah Chiu, Francis T. F. Tsai | |||
| The TNF receptor 1: a split personality complex.(tumor necrosis factor) | Biological sciences | Bryan C. Barnhart, Marcus E. Peter | |||
| The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by COP9 signalosome in response to DNA damage. | Biological sciences | Yoshihiro Nakatani, Regina Groisman, Ronny Drapkin, Kiyoji Tanaka, Jun-ichi Sawada, Jolanta Polanowska, Isao Kuraoka, Masafumi Saijo, Alexei F. Kisselev | |||
| The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. | Biological sciences | Nicolas Manel, Felix J. Kim, Sandrina Kinet, Naomi Taylor, Marc Sitbon, Jean-Luc Battini | |||
| The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader.(open reading frame) | Biological sciences | Randal J. Kaufman, Ibrahim Yaman, James Fernandez, Mark Caprara, Anton A. Komar, Antonis E. Koromilas, Lingyin Zhou, Martin D. Snider, Donalyn Scheuner, Maria Hatzoglou, Haiyan Liu | |||
| TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism.(tissue inhibitors of metalloproteinase)(matrix metalloproteinase) | Biological sciences | Dong-Wan Seo, Hongmei Li, Liliana Guedez, Paul T. Wingfield, Tere Diaz, Rita Salloum, Bei-yang Wei, William G. Stetler-Stevenson | |||
| Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. | Biological sciences | Cynthia Kenyon, Nataliya Libina, Jennifer R. Berman | |||
| Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC. | Biological sciences | Marc W. Kirschner, Nagi G. Ayad, Susannah Rankin, Monica Murakami, Judith Jebanathirajah, Steven Gygi | |||
| Toxin-antitoxin pairs in bacteria: killers or stress regulators? | Biological sciences | Christopher S. Hayes, Robert T. Sauer | |||
| Transcription factors prominently in Lasker Award to Roeder.(Essays) | Biological sciences | Susan M. Abmayr, Jerry L. Workman | |||
| tRNA structure goes from L to lambda. | Biological sciences | Paul Schimmel, Koji Tamura | |||
| TSC2 mediates cellular energy response to control cell growth and survival. | Biological sciences | Kun-Liang Guan, Ken Inoki, Tianqing Zhu | |||
| TSH is a negative regulator of skeletal remodeling.(thyroid stimulating hormone) | Biological sciences | Terry F. Davies, Etsuko Abe, Russell C. Marians, Wanqin Yu, Xue-Bin Wu, Takao Ando, Yanan Li, Jameel Iqbal, Leslie Eldeiry, Gopalan Rajendren, Harry C. Blair, Mone Zaidi | |||
| TSH, the bone suppressing hormone.(thyroid-stimulating hormone) | Biological sciences | Deborah Veis Novack | |||
| Tube morphogenesis: making and shaping biological tubes. | Biological sciences | Mark A. Krasnow, Barry Lubarsky | |||
| Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. | Biological sciences | Dong Zhang, Zusen Fan, Paul J. Beresford, David Y. Oh, Judy Lieberman | |||
| Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. | Biological sciences | James A. Richardson, Eric N. Olson, David M. Ornitz, Drazen Sosic, Kai Yu | |||
| Two-photon calcium imaging reveals an odor-evoked map of activity in the fly brain. | Biological sciences | Leslie B. Vosshall, Allan M. Wong, Richard Axel, Jing W. Wang, Jorge Flores | |||
| Two poles and a compass. | Biological sciences | Ruedi Meili, Richard A. Firtel | |||
| Two populations of node monocilia initiate left-right asymmetry in the mouse. | Biological sciences | Stefan Somlo, James McGrath, Svetlana Makova, Xin Tian, Martina Brueckner | |||
| Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120. | Biological sciences | Dennis R. Burton, Michael Farzan, Eric S. Rosenberg, Peter D. Kwong, Hyeryun Choe, Wenhui Li, Paulette L. Wright, Natalya Vasilieva, Miro Venturi, Chih-Chin Huang, Christoph Grundner, Tatyana Dorfman, Michael B. Zwick, Liping Wang, James E. Robinson, Joseph G. Sodroski | |||
| Ubiquitinating a phosphorylated Cdk inhibitor on the blades of the Cdc4 beta-propeller. | Biological sciences | Peter K. Jackson | |||
| Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking. | Biological sciences | Jeff Gelles, Robert Landick, Steven M. Block, Keir C. Neuman, Elio A. Abbondanzieri | |||
| UV irradiation triggers ubiquitin-dependent degradation of p21(sup)WAF1 to promote DNA repair. | Biological sciences | Alain Sarasin, Mourad Bendjennat, Jerome Boulaire, Thomas Jascur, Howard Brickner, Valerie Barbier, Arun Fotedar, Rati Fotedar | |||
| Variation on an Src-like theme.(Minireview) | Biological sciences | Stephen C. Harrison | |||
| Vesicle-mediated export and assembly of pore-forming oligomers of the enterobacterial ClyA cytotoxin. | Biological sciences | Sun Nyunt Wai, Tomas Soderblom, Agneta Richter-Dahlfors, Bernt Eric Uhlin, Yoshimitsu Mizunoe, Jana Jass, Barbro Lindmark, Akemi Takade, Marie Westermark, Jan Oscarsson | |||
| Visualization of the target-membrane-inserted fusion protein of semliki forest virus by combined electron microscopy and crystallography. | Biological sciences | Don L. Gibbons, Inge Erk, Brigid Reilly, Jorge Navaza, Margaret Kielian, Felix A. Rey, Jean Lepault | |||
| Visualizing genetic influences on human brain functions. | Biological sciences | John D. E. Gabrieli, Alison R. Preston | |||
| Wnt signaling induces the myogenic specification of resident CD45 (super)+ adult stem cells during muscle regeneration. | Biological sciences | Patrick Seale, Michael A. Rudnicki, Anna Polesskaya | |||
| X-ray structures of Myc-Max and Mad-Max recognizing DNA: molecular bases of regulation by proto-oncogenic transcription factors. | Biological sciences | Stephen K. Burley, Satish K. Nair | |||
| Zic2 patterns binocular vision by specifying the uncrossed retinal projection. | Biological sciences | Stephen Brown, Carol A. Mason, Jun Aruga, Katsuhiko Mikoshiba, Eloisa Herrera, Lucia Brown, Rivka A. Rachel, Gul Dolen | |||
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