| Genes & Development 2000 |
| Title | Subject | Authors |
|---|
| Aberrant cell cycle checkpoint function and early embryonic death in Chka (-/-) mice. | Biological sciences | Kei-ichi Nakayama, Noboru Motoyama, Kyoji Ikeda, Makoto Nakanishi, Hiroyuki Takai, Kaoru Tominaga, Yohji A. Minamishima, Hiroyasu Nagahama, Tadasuke Tsukiyama, Keiko Nakayama |
| Ablation of the Retinoblastoma gene family deregulates G(sub.1) control causing immortalization and increased cell turnover under growth-restricting conditions.(Statistical Data Included) | Biological sciences | Jan-Hermen Dannenbert, Agnes Van Rossum, Leontine Schuijff, Hein Te Riele |
| Absence of Wee1 ensures the meiotic cell cycle in Xenopus oocytes.(Statistical Data Included) | Biological sciences | Nobushige Nakajo, Satoshi Yoshitome, Jun Iwashita, Maki Iida, Katsuhiro Uto, Shuichi Ueno, Kengo Okamoto, Noriyuki Sagata |
| A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene.(Statistical Data Included) | Biological sciences | Hong Zhang, Scott W. Emmons |
| A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis.(Caenorhabditis elegans)(Statistical Data Included) | Biological sciences | Patricia E. Kuwabara, Min-Ho Lee, Tim Schedl, Gregory S.X.E. Jefferis |
| A cell cycle-dependent protein serves as a template-specific translation initiation factor.(Statistical Data Included) | Biological sciences | Tatyana V. Pestova, Evgeny V. Pilipenko, Victoria G. Kolupaeva, Elena V. Khitrina, Angela N. Poperechnaya, Vadim I. Agol, Christopher U.T. Hellen |
| A common enzyme connects Notch signaling and Alzheimer's disease. | Biological sciences | Raphael Kopan, Alison Goate |
| A conserved family of calcineurin regulators. | Biological sciences | Tami J. Kingsbury, Kyle W. Cunningham |
| A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness.(silencing mediator for retinoid and thyroid receptors) | Biological sciences | Matthew G. Guenther, Mitchell A. Lazar, William S. Lane, Wolfgang Fischle, Eric Verdin, Ramin Shiekhattar |
| A critical role of sterols in embryonic patterning and meristem programming revealed by the fackel mutants of Arabidopsis thaliana. | Biological sciences | Jyan-Chrun Jang, Shozo Fujioka, Masao Tasaka, Hideharu Seto, Suguru Takatsuto, Akira Ishii, Mitsuhiro Aida, Shigeo Yoshida, Jen Sheen |
| Activation mutants in yeast RNA polymerase II subunit RPB3 provide evidence for a structurally conserved surface required for activation in eukaryotes and bacteria.(Statistical Data Included) | Biological sciences | Qian Tan, K. Liisi Linask, Richard H. Ebright, Nancy A. Woychik |
| Activin receptor patterning of foregut organogenesis.(Statistical Data Included) | Biological sciences | En Li, Seung K. Kim, Matthias Hebrok, S. Paul Oh, Heinrich Schrewe, Erin B. Harmon, Joon S. Lee, Douglas A. Melton |
| A Drosophila I(kappa)B kinase complex required for Relish cleavage and antibacterial immunity. | Biological sciences | Tom Maniatis, Neal Silverman, Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark |
| A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-2 cooperate to activate EGF receptor signaling. | Biological sciences | Jonathan D. Wasserman, Sinisa Urban, Matthew Freeman |
| A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle. | Biological sciences | Asa Blixt, Margit Mahlapuu, Marjo Aitola, Markku Pelto-Huikko, Sven Enerback, Peter Carlsson |
| A Kruppel-like zinc finger protein is involved in nitrogen-fixing root nodule organogenesis. | Biological sciences | Frugier Florian, Simone Poirier, Beatrice Satiat-Jeunemaitre, Adam Kondorosi, Martin Crespi |
| A major surface glycoprotein of Trypanosoma brucei is expressed transiently during development and can be regulated post-transcriptionally by glycerol or hypoxia. | Biological sciences | Erik Vassella, Jan Van Den Abbeele, Peter Butikofer, Christina Kunz Renggli, Andre Furger, Reto Brun, Isabel Roditi |
| A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappaB/RelA.(transforming growth factor, RelA subunit of nuclear factor kappa B) | Biological sciences | Markus Bitzer, Gero Von Gersdorff, Dan Liang, Alfredo Dominguez-Rosales, Amer A. Beg, Marcos Rojkind, Erwin P. Bottinger |
| A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiation tRNA(super.Met) is an important translation initiation intermediate in vivo.(translation initiation factors 1, 2, 3, 5) | Biological sciences | Katsura Asano, Jason Clayton, Anath Shalev, Alan G. Hinnebusch |
| Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar.(Statistical Data Included) | Biological sciences | Jen Sheen, Francisco Arenas-Huertero, Analilia Arroyo, Li Zhou, Patricia Leon |
| Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. | Biological sciences | David H. Mack, Arnold J. Levine, Renbin Zhao, Kurt Gish, Maureen Murphy, Yuxin Yin, Daniel Notterman, William H. Hoffman, Edward Tom |
| Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. | Biological sciences | Yasuhiko Takahashi, Joseph B. Rayman, Brian David Dynlacht |
| An aminoacylation-dependent nuclear tRNA export pathway in yeast. | Biological sciences | Helge Grosshans, Ed Hurt, George Simos |
| An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes. | Biological sciences | Dorian McIlroy, Masato Tanaka, Hideki Sakahira, Hidehiro Fukuyama, Misao Suzuki, Ken-ichi Yamamura, Yoshiyuki Ohsawa, Yasuo Uchiyama, Shigekazu Nagata |
| An essential role in liver development for transcription factor XBP-1. | Biological sciences | Andreas M. Reimold, Amit Etkin, Isabelle Clauss, Andrew Perkins, Daniel S. Friend, John Zhang, Heidi F. Horton, Andrew Scott, Stuart H. Orkin, Michael C. Byrne, Michael J. Grusby, Laurie H. Glimcher |
| An evolutionarily conserved RNA semi-loop functions as a sensor that directs feedback regulation of RNase E gene expression. | Biological sciences | Alexis Diwa, Angela L. Bricker, Chaitanya Jain, Joel G. Belasco |
| A nonproteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M phase. | Biological sciences | Atsuya Nishiyama, Kazunori Tachibana, Yuko Igarashi, Hideyo Yasuda, Nobuyuki Tanahashi, Keiji Tanaka, Keita Ohsumi, Takeo Kishimoto |
| A novel pairing process promoted by Escherichia coli RecA protein: inverse DNA and RNA strand exchange. | Biological sciences | Eugene N. Zaitsev, Stephen C. Kowalczykowski |
| A novel Smad nuclear interacting protein, SHIP1, suppresses p300-dependent TGF-beta. | Biological sciences | Richard H. Kim, David Wang, Michael Tsang, Jennifer Martin, Carla Huff, Mark P. De Caestecker, W. Tony Parks, Xianwang Meng, Robert J. Lechleider, Tongwen Wang, Anita B. Roberts |
| A novel two-component hybrid molecule regulates vascular morphogenesis of the Arabidopsis root.(Statistical Data Included) | Biological sciences | Philip N. Benfey, Ari Pekka Mahonen, Martin Bonke, Leila Kauppinen, Marjukka Riikonen, Yka Helariutta |
| Antagonism between C-EBP(beta) and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors.(Friend of GATA) | Biological sciences | Thomas Graf, Erich Querfurth, Mikkel Schuster, Holger Kulessa, John D. Crispino, Gabriele Diderlein, Stuart Orkin, Claus Nerlov |
| Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation. | Biological sciences | Matthias Kieslinger, Irina Woldman, Richard Moriggle, Johannes Hofmann, Jean-Christophe Marine, James N. Ihle, Harmut Beug, Thomas Decker |
| Arabidopsis NAC1 transduces auxin signal downstream of TIR1 to promote lateral root development.(Statistical Data Included) | Biological sciences | Nam-Hai Chua, Qi Xie, Giovanna Frugis, Diana Colgan |
| A role for neural determination genes in specifying the dorsoventral identity of telecephalic neurons. | Biological sciences | Carol Fode, Qiufu Ma, Simona Casarosa, Siew-Lan Ang, David J. Anderson, Francois Muillemot |
| A subtilisin-like serine protease involved in the regulation of stomatal density and distribution of Arabidopsis thaliana. | Biological sciences | Dieter Berger, Thomas Altmann |
| ATP can be dispensable for prespliceosome formation in yeast. | Biological sciences | Rhonda Perriman, Manuel Ares Jr. |
| A transcriptional insulator at the imprinted H19/Igf2 locus.(Statistical Data Included) | Biological sciences | Kye-Yoon Park, Alexander Grinberg, Madhulika Srivastava, Sandra Hsieh, Sing-Ping Huang, Karl Pfeifer, Christopher R. Kaffer, Elizabeth Ives, Juan Batlle |
| ATR disruption leads to chromosomal fragmentation and early embryonic lethality. | Biological sciences | David Baltimore, Eric J. Brown |
| BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.(BRCA1-associated genome surveillance complex) | Biological sciences | Stephen J. Elledge, Yi Wang, Parvin Yazdi, David Cortez, Norma Neff, Jun Qin |
| BCoR, a novel corepressor involved in BCL-6 repression.(Statistical Data Included) | Biological sciences | Wolfgang Fischle, Eric Verdin, Khanh D. Huynh, Vivian J. Bardwell |
| Bel-2 antiapoptotic protein mediates verotoxin II-induced cell death: possible association between Bcl-2 and tissue failure by E. coli O157:H7. | Biological sciences | Atsuchi Suzuki, Hirofumi Doi, Fumiko Matsuzawa, Si-ichi Aikawa, Kyoko Takiuchi, Hirokazu Kawano, Midori Hayashida, Susumu Ohno |
| Bromodomain factor 1 corresponds to a missing piece of yeast TFIID. | Biological sciences | Oranart Matangkasombut, Robin M. Buratowski, Nathan W. Swilling, Stephen Buratowski |
| Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis.(Statistical Data Included) | Biological sciences | Paul Kalitsis, Elizabeth Earle, Kerry J. Fowler, K.H. Andy Choo |
| Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. | Biological sciences | Takeshi Yagi, Masatoshi Takeichi |
| (CA/GT)(sub.n) microsatellites affect homologous recombination during yeast meiosis. | Biological sciences | Christiane-Gabrielle Gendrel, Annick Boulet, Marie Dutreis |
| Cap methyltransferase selective binding and methylation of GpppG-RNA are stimulated by importin-alpha.(Statistical Data Included) | Biological sciences | Yingxia Wen, Aaron J. Shatkin |
| CBP/p300 in cell growth, transformation, and development. | Biological sciences | Richard H. Goodman, Sarah Snolik |
| Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro. | Biological sciences | Tohru Mizushima, Naoko Takahashi, Bruce Stillman |
| Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1.(Statistical Data Included) | Biological sciences | Birgit Otzen Petersen, Christian Wagener, Federica Marinoni, Edgar R. Kramer, Marina Melixetian, Lazzerini Eros Denchi, Christian Gieffers, Cristian Matteucci, Jan-Michael Peters, Kristian Helin |
| Cell cycle-regulated phosphorylation of p220(super.NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription.(Statistical Data Included) | Biological sciences | Jun Qin, Jin Wang, Tianlin Ma, Brian A. Van Tine, Yue Wei, Michelle D. Garrett, David Nelson, Peter D. Adams, Louise T. Chow, J. Wade Harper |
| Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invation and angiogenesis. | Biological sciences | Qin Yu, Ivan Stamenkovic |
| Chaperone HSP27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes. | Biological sciences | Robert J. Schneider, Rafael Cuesta, Gaurav Laroia |
| Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.(Statistical Data Included) | Biological sciences | Kim Nasmyth, Takeshi Tomonaga, Koji Nagao, Yosuke Kawasaki, Kanji Furuya, Akiki Murakami, Jun Morishita, Tatsuro Yuasa, Takashi Sutani, Stephen E. Kearsey, Frnk Uhlmann, Mitsihiro Yanagida |
| Chk1 is an essential kinase that is regulated by Atr and required for the G(sub.2)/M DNA damage checkpoint. | Biological sciences | Qinghua Liu, Stephen J. Elledge, Katsuyuki Tamai, Saritha Guntuku, Xian-shu Cui, Shuhei Matsuoka, Dvid Cortez, Guangbin Luo, Sandra Carattini-Rivera, Francisco DeMayo, Allan Bradley, Larry A. Donehower |
| Chk2/hCds1 functions as a DNA damage checkpoint in G (sub)1 by stabilizing p53.(Statistical Data Included) | Biological sciences | Nabil H. Chehab, Asra Malikzay, Michael Appel, Thanos D. Halazonetis |
| Chromatin fine structure profiles for a developmentally regulated gene: reorganization of the lysozyme locus before trans-activator binding and gene expression.(Statistical Data Included) | Biological sciences | Joanna Kontaraki, Hsiu-Hua Chen, Arthur Riggs, Constanze Bonifer |
| CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex.(major histocompatibility complex) | Biological sciences | Walter Reith, Krzysztof Masternak, Annick Muhlethaler-Mottet, Jean Villard, Madeleine Zufferey, Viktor Steimle |
| c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.(microphthalmia)(Statistical Data Included) | Biological sciences | Min Wu, Timothy J. Hemesath, Clifford M. Takemoto, Martin A. Horstmann, Audrey G. Wells, E. Roydon Price, Daniel Z. Fisher, David E. Fisher |
| CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP. | Biological sciences | Ueli Schibler, Jurgen A. Ripperger, Lauren P. Shearman, Steven M. Reppert |
| Complete lack of NF-(kappa)B activity in IKK1 and IKK2 double-deficient mice: aditional defect in neurulation. | Biological sciences | Qiutang Li, Gabriela Estepa, Sylvie Memet, Alain Israel, Inder M. Verma |
| Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2. | Biological sciences | Anton Berns, Marco Biovannini, Els Robanus-Maandag, Martin Van der Valk, Michiko Niwa-Kawakita, Vincent Abramowski, Laurence Goutebroze, James M. Woodruff, Gilles Thomas |
| Conserved and divergent mechanisms in left-right axis formation. | Biological sciences | Alexander F. Schier, Rebecca D. Burdine |
| Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice.(erythroid kruppel-like factor) | Biological sciences | James Douglas Engel, Keiji Tanimoto, Frank Grosveld, Qinghui Liu, Jorg Bungert |
| Controlling TGF-beta signaling.(transforming growth factor) | Biological sciences | Joan Massague, Ye-Guang Chen |
| Control of her1 expression during zebrafish somitogenesis by a Delta-dependent oscillator and an independent wave-front activity. | Biological sciences | Scott A. Holley, Robert Geisler, Christiane Nusslein-Volhard |
| Cooperative effects of genes controlling the G(sub.2)/M checkpoint. | Biological sciences | Bert Vogelstein, Timothy A. Chan, Paul M. Hwang, Heiko Hermeking, Kinzler. Kenneth W. |
| Coregulation of anterior and posterior mesendodermal development by a hairy-related transcriptional repressor. | Biological sciences | Wolfgang Wurst, Laure Bally-Cuif, Carole Goutel, Marion Wassef, Frederic Rosa |
| CPEB proteins control two key steps in spermatogenesis in C. elegans.(Caenorhabditis elegans, cytoplasmic polyadenylation element binding)(Statistical Data Included) | Biological sciences | Cameron Luitjens, Maria Gallegos, Brian Kraemer, Judith Kimble, Marvin Wickens |
| D114, a novel Notch ligand expressed in arterial endothelium.(Statistical Data Included) | Biological sciences | John R. Shutter, Sheila Scully, Wei Fan, William G. Richards, Jan Kitajewski, Gisele A. Deblandre, Chris R. Kintner, Kevin L. Stark |
| daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. | Biological sciences | Adam Antebi, Wen-Hui Yeh, Danilo Tait, Edward M. Hedgecock, Donald L. Riddle |
| Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm. | Biological sciences | Youngsoo Lee, Deborah E. Barnes, Tomas Lindahl, Peter J. MKiknnon |
| Defective processing of methylated single-stranded DNA by E. coli alkB mutants.(Statistical Data Included) | Biological sciences | Tomas Lindahl, Suneet Dinglay, Sarah C. Trewick, Barbara Sedgewick |
| Degradation of Drosophila PIM regulates sister chromatid separation during mitosis.(Statistical Data Included) | Biological sciences | Oliver Leismann, Alf Herzig, Stefan Heidmann, Christian F. Lehner |
| De novo nucleosome assembly: new pieces in an old puzzle. | Biological sciences | |
| Dictyostelium RasD is required for normal phototaxis, but not differentiation.(Statistical Data Included) | Biological sciences | Andrew Wilkins, Meenal Khosla, Derek J. Fraser, George B. Spiegelman, Paul R. Fisher, Gerald Weeks, Robert H. Insall |
| Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters.(Transcription factor IIIB)(Statistical Data Included) | Biological sciences | Laura Schramm, P. Shannon Pendergrast, Yuling Sun, Nouria Hernandez |
| Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. | Biological sciences | Stephen Buratowski, Philip Komarnitsky, Eun-Jung Cho |
| Dimerization and nuclear entry of mPER proteins in mammalian cells.(Statistical Data Included) | Biological sciences | Jan H.J. Hoeijmakers, Kazuhiro Yagita, Shun Yamaguchi, Filippo Tamanini, Gijsbertus T.J. van der Horst, Akira Yasui, Jennifer J. Loros, Jay C. Dunlap, Hitoshi Okamura |
| Direct protein-protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegans.(Statistical Data Included) | Biological sciences | Patricia E. Kuwabara, David H. Lum, David Zarkower, Andrew M. Spence |
| Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway.(microphthalmia-associated transcription factor) | Biological sciences | Richard I. Dorsky, David W. Raible, Randall T. Moon |
| Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.(Statistical Data Included) | Biological sciences | Mary E. Hatten, Rupal S. Bhatt, Toshifumi Tomoda, Yin Fang |
| Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.(Statistical Data Included) | Biological sciences | Kazushi Inoue, Renren Wen, Jerold E. Rehg, Masashi Adachi, John L. Cleveland, Martine F. Roussel, Charles J. Sherr |
| Distinct protein interaction domains and protein spreading in a complex centromere. | Biological sciences | Janet F. Partridge, Britta Borgstrom, Robin C. Alllshire |
| Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation. | Biological sciences | Vivian J. Bardwell, David Zarkower, Chrisopher S. Raymond, Mark W. Murphy, M. Gerard O'Sullivan |
| Doing the MATH: Is the mouse a good model for fly development?(Statistical Data Included) | Biological sciences | Hugo J. Bellen, Bassem A. Hassan |
| Drosophila double parked: a conserved essential replication protein that colocalized with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts.(Statistical Data Included) | Biological sciences | Allyson J. Whittaker, Irena Royzman, Terry L. Orr-Weaver |
| Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification. | Biological sciences | Muriel Boube, Christian Faucher, Laurent Joulia, David L. Cribbs, Henri-Marc Bourbon |
| Drosophila SNS, a member of the immunoglobulin superfamily that is essential for myoblast fusion. | Biological sciences | Barbara A. Bour, Malabika Chakravarti, Joshua M. West, Susan M. Abmayr |
| Dual role for Drosophila epidermal growth factor receptor signaling in early wing disc development.(Statistical Data Included) | Biological sciences | Shu-Huei Wang, Amanda Simcox, Gerard Campbell |
| Dual utilization of an acceptor/donor splice site governs the alternative splicing of the IRF-3 gene. | Biological sciences | Alla Y. Karpova, Peter M. Howley, Lucienne V. Ronco |
| Dynamic association of capping enzymes with transcribing RNA polymerase. | Biological sciences | Stewart Shuman, Stephanie C. Schroeder, Beate Schwer, David Bentley |
| Dynamic organization of chromosomal DNA in Escherichia coli. | Biological sciences | Hironori Niki, Yoshiharu Yamaichi, Sota Hiraga |
| E2f3 is critical for normal cellular proliferation. | Biological sciences | Patrick O. Humbert, Raluca Verona, Jeffrey M. Trimarchi, Catherine Rogers, Savita Dandapani, Jacqueline A. Lees |
| E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis.(epithelial microtubule-associated protein of 115 kD)(Statistical Data Included) | Biological sciences | Masayuki Komada, Derek J. McLean, Michael D. Griswold, Lonnie D. Russell, Philippe Soriano |
| Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa. | Biological sciences | Chikahide Masutani, Fumio Hanaoka, Eiji Ohashi, Tomoo Ogi, Rika Kusumoto, Shigenori Iwai, Haruo Ohmori |
| Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. | Biological sciences | Robert A. Weinberg, Cathrin Brisken, Anna Heineman, Tony Chavarria, Brian Elenbaas, Jian Tan, Sudhansu K. Dey, Jill A. McMahon, Andrew P. McMAhon |
| Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems. | Biological sciences | Min Liu, Fred A. Pereira, Steven D. Price, Mei-jin Chu, Cindy Shope, Donna Himes, Ruth Anne Eatock, William E. Brownell, Anna Lysakowski, Ming-Jer Tsai |
| Essential role of Max in early embyronic growth and development.(Statistical Data Included) | Biological sciences | Hong Shen-Li, Ronan C. O'Hagan, Harry Hou Jr., James W. Horner II, Han-Woong Lee, Ronald DePinho |
| Exploring the transcription-chromatin interface.(Statistical Data Included) | Biological sciences | Katherine A. Janes, James T. Kadonaga |
| FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis. | Biological sciences | Gerd Jurgens, Kathrin Schrick, UIrike Mayer, Andrea Horrichs, Christine Kuhnt, Catherine Bellini, Jeff Dangl, Jurgen Schmidt |
| FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development.(Statistical Data Included) | Biological sciences | Xing Wang Deng, Hsu-Liang Hsieh, Haruko Okamoto, Mingli Wang, Lay-Hong Ang, Minami Matsui, Horward Goodman |
| Fra-1 replaces c-Fos-dependent functions in mice.(Statistical Data Included) | Biological sciences | Alexander Fleischmann, Erwin F. Wagner, Farhad Hafezi, Candace Elliott, Charlotte E. Reme, Ulrich Ruther |
| FtsK functions in the processing of a Holliday junction intermediate during bacterial chromosome segregation.(Statistical Data Included) | Biological sciences | David J. Sherratt, Francois-Xavier Barre, Mira Aroyo, Sean D. Colloms, Annett Helfrich, Francois Cornet |
| Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.(Statistical Data Included) | Biological sciences | Stephen J. Elledge, David Cortez, Ralph Scully, Randal S. Tibbetts, Kathryn M. Brumbaugh, David Livingston, Robert T. Abraham |
| Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.(Statistical Data Included) | Biological sciences | Frank T. Kolligs, Barbara Kolligs, Karen M. Hajra, Gang Hu, Masachika Tani, Kathleen R. Cho, Eric R. Fearon |
| Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.(CREB-binding protein)(Statistical Data Included) | Biological sciences | Andrew L. Kung, Vivienne I. Rebel, Roderick T. Bronson, Lian-Ee Ch'ng, Colin A. Sieff, David M. Livingston, Tso-Pang Yao |
| Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin.(Statistical Data Included) | Biological sciences | Sean Oldham, Jacques Montagne, Thomas Radimerski, George Thomas, Ernst Hafen |
| Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation.(Statistical Data Included) | Biological sciences | Veronica P.C.C. Yu, Michael Koehler, Claus Steinlein, Michael Schmid, Leslyn A. Hanakahi, Alain J. van Gool, Stephen West C., Ashok R. Venkitaraman |
| H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19. | Biological sciences | Alexander Grinberg, Madhulika Srivastava, Sandra Hsieh, Lisa Williams-Simons, Sing-Ping Huang, Karl Pfeifer |
| HAESA, an Arabidopsis leucine-rich repeat receptor kinase, controls floral organ abscission. | Biological sciences | Tsung-Leo Jinn, Julie M. Stone, John C. Walker |
| Head and trunk in zebrafish arise via coinhibition of BMP signaling by bozozok and chordino. | Biological sciences | Christopher V.E. Wright, Encina M. Gonzalez, Kimberly Fekany-Lee, Amanda Carmany-Rampey, Caroline Erter, Jacek Topeczewski, Lilianna Solnica-Krezel |
| Hfq(HF1) stimulates ompA mRNA decay by interfering with ribosome binding.(Host factor 1, outer membrane protein A) | Biological sciences | Oresta Vytvytska, Isabella Moll, Vladimir R. Kaberdin, Alexander von Gabain, Udo Blasi |
| HFR1 encodes an atypical bHLH protein that acts in phytochrome A signal transduction. | Biological sciences | Craig D. Fairchild, Michael A. Schumaker, Peter H. Quail |
| HIF-1 and human disease: one highly involved factor.(Statistical Data Included) | Biological sciences | Gregg L. Semenza |
| High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation.(Statistical Data Included) | Biological sciences | John T. Lis, Janis Werner, Erik D. Andrulis, Ernesto Guzman, Pascal Doring |
| Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif. | Biological sciences | Stephane Germain, Michael Howell, Graeme M. Esslemont, Caroline S. Hill |
| Hormones in male sexual development.(Review) | Biological sciences | Serge Nef, Luis F. Parada |
| Hypersensitivity to DNA damage leads to increased apoptosis during early mouse development.(Statistical Data Included) | Biological sciences | Babette S. Heyer, Alasdair MacAuley, Ole Behrendtsen, Zena Web |
| Identification and disruption of an Arabidopsis zinc finger gene controlling seed germination. | Biological sciences | Maura Papi, Sabrina Sabatini, David Bouchez, Christine Camilleri, Paolo Costantino, Paola Birrorioso |
| Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress.(Statistical Data Included) | Biological sciences | Robert S. Weiss, Tamar Enoch, Philip Leder |
| Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. | Biological sciences | Anton Berns, Silvia Marino, Marc Vooijs, Hanneke Van der Gulden, Jos Jonkers |
| Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells.(mitogen-activated protein (MAP)) | Biological sciences | Michael Karin, Pier Lorenzo Puri, Zhenguo Wu, Peilin Zhang, Lauren D. Wood, Kunjan S. Bhakta, Jiahuai Han, James R. Feramisco, Jean Y.J. Wang |
| Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein. | Biological sciences | Michiru Nishita, Hiroshi Shibuya, Ken-ichi Tago, Tsutomu Nakamura, Junko Hyodo, Shin-ichi Nagai, Yoji Murata, Shungo Adachi, Susumu Ohwada, Yasuo Morishita, Tetsu Akiyama |
| Inhibitor of striate conditionally suppresses cell proliferation in variegated maize. | Biological sciences | Sung Han Park, Hang Gyeong Chin, Moo Je Cho, Robert A. Martienssen, Chang-deok Han, Su Hyun Park |
| Interactions with Costal2 and Suppressor of Fused regulate nuclear translocation and activity of Cubitus interruptus. | Biological sciences | Jin Jiang, Bing Wang, Kazuhito Amanai, Gelin Wang |
| Involvement of the MAP kinase cascade in resetting of the mammalian circadian clock. | Biological sciences | Makoto Akahi, Eisuke Nishida |
| Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. | Biological sciences | Hung-Ying Kao, Michael Downes, Peter Ordentlich, Ronald M. Evans |
| Ku acts in a unique way at the mammalian telomere to prevent end joining. | Biological sciences | Beth Allen, Terumi Kohwi-Shigematsu, David J. Chen, Gloria C. Li, Hsin-Ling Hsu, David Gilley, Sanjeev A. Galande, M. Prakash Hande, Sahn-Ho Kim, Judith Campisi |
| Ku complex interacts with and stimulates the Werner protein. | Biological sciences | Marcus P. Cooper, Amrita Machwe, David K. Orren, Robert M. Brosh, Dale Ramsden, Vilhelm A. Bohr |
| Leptin-specific patterns of gene expression in white adipose tissue. | Biological sciences | Alexander Soukas, Paul Joseph Cohen, Nicholas D. Socci, Jeffrey M. Friedman |
| Light: an indicator of time and place.(Statistical Data Included) | Biological sciences | Joanne Chory, Michael M. Neff, Christian Fankhauser |
| Lineage commitment in the immune system: the T helper lymphocyte grows up. | Biological sciences | Laurie H. Glimcher, Kenneth M. Murphy |
| Long palindromes formed in Streptomyces by nonrecombinational intra-strand annealing.(Statistical Data Included) | Biological sciences | Zhongjun Qin, Stanley N. Cohen |
| Loss of PTEN facilitates HIF-1-mediated gene expression.(tumor suppressor gene PTEN) | Biological sciences | Wayne Zundel, Cornelia Schindler, Daphne Haas-Kogan, Albert Koong, Fiona Kaper, Eucice Chen, Alexander R. Gottshalk, Heather E. Ryan, Randall S. Johnson, Anne B. Jefferson, David Stokoe, Amato J. Giaccia |
| Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. | Biological sciences | Jixuan Li, Gang Ning, Stephen A. Duncan |
| Matrix metalloproteinases: effectors of development and normal physiology.(Statistical Data Included) | Biological sciences | Thiennu H. Vu, Zena Werb |
| Mcl-1 deficiency results in peri-implantaion embryonic lethality.(Statistical Data Included) | Biological sciences | Julie L. Rinkenberger, Susan Horning, Barbara Clocke, Kevin Roth, Stanley J. Korsmeyer |
| Mcm10 and the MCM1-7 complex interact to initiate DNA synthesis and to release replication factors from origins. | Biological sciences | Lisa Homesley, Ming Lei, Yasuo Kawasaki, Sara Sawyer, Tim Christensen, Bik K. Tye |
| Mechanisms of Hox gene colinearity: transposition of the anterior Hoxb1 gene into the posterior HoxD complex. | Biological sciences | Marie Kmita, Frank Van der Hoeven, Jozsef Zakany, Robb Krumlauf, Denis Duboule |
| MEI-1/MEI-2 katanin-like microtubule severing activity is required for Caenorhabditis elegans meiosis. | Biological sciences | Martin Strayko, Dan W. Buster, Omar A. Bazirgan, Francis J. McNally, Paul E. Mains |
| members only encodes a Drosophila nucleoporin required for Rel protein import and immune response activation.(Statistical Data Included) | Biological sciences | Anne E. Uv, Peggy Roth, Nikos Xylourgidis, Anna Wickberg, Rafael Cantera, Christos Samakovlis |
| Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage. | Biological sciences | Colin R. Goding |
| Molecular genetics of prostate cancer. | Biological sciences | Michael M. Shen, Cory Abate-Shen |
| Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. | Biological sciences | Katsuyuki Tamai, Yoichi Taya, Rosalie Sears, Faison Nuckolls, Eric Haura, Joseph Nevins |
| Multiple RGS proteins alter neural G protein signaling to allow C. elegans to rapidly change behavior when fed.(Caenorhabditis elegans)(Statistical Data Included) | Biological sciences | Meng-Qiu Dong, Daniel Chase, Georgia A. Patikoglou, Michael R. Koelle |
| mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development. | Biological sciences | Michael H. Brodsky, Jeff J. Sekelsky, Garson Tsang, R. Scott Hawley, Gerald M. Rubin |
| Mutation of a Drosophila gamma tubulin ring complex subunit encoded by discs degenerate-4 differentially disrupts centrosomal protein localization.(Statistical Data Included) | Biological sciences | Vitor Barbosa, Rochele R. Yamamoto, Daryl S. Henderson, David M. Glover |
| MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. | Biological sciences | Harry Hou Jr., Burkhard Kneitz, Paula E. Cohen, Elena Avdievich, Liyin Zhu, Michael F. Kane, Richartd D. Kolodner, Raju Kucherlapati, Jeffrey W. Pollard, Winfried Edelmann |
| Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression.(Statistical Data Included) | Biological sciences | Ronan C. O'Hagan, Frederick W. Alt, Michael Ohh, Gregory David, Agnacio Moreno De Alboran, William G. Kaelin Jr, Ronald A. De Pinho |
| Neural patterning: the role of Nkx genes in the ventral spinal cord. | Biological sciences | Andrew P. McMahon |
| Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system.(Statistical Data Included) | Biological sciences | Miriam Bibel, Yves-Alain Barde |
| N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation.(Statistical Data Included) | Biological sciences | Ronan C. O'Hagan, Roderick Bronson, Ronald A. DePinho, Barbara A. Malynn, Ignacio Moreno de Alboran, Laurie Davidson, Frederick W. Alt |
| Notch signaling is essential for vascular morphogenesis in mice.(Statistical Data Included) | Biological sciences | John R. Shutter, Jan Kitajewski, Kevin L. Stark, Luke T. Krebs, Yingzi Xue, Christine R. Norton, Maureen Maguire, John P. Sundberg, Daniel Gallahan, Violaine Closson, Robert Callahan, Gilbert H. Smith, Thomas Gridley |
| Novel gene expressed in nasal region influences outgrowth of olfactory axons and migration of luteinizing hormone-releasing hormone (LHRH) neurons.(Statistical Data Included) | Biological sciences | P.R. Kramer, Susan Wray |
| NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription.(Statistical Data Included) | Biological sciences | Jiyong Zhao, Brian K. Kennedy, Brandon D. Lawrence, David A. Barbie, A. Gregory Matera, Jonathan A. Fletcher, Ed Harlow |
| NUC-1, a Caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis. | Biological sciences | Yi-Chun Wu, Gillian M. Stanfield, H. Robert Horvitz |
| Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human beta-globin locus. | Biological sciences | Dirk Schubeler, Claire Francastel, Daniel M. Cimbora, Andreas Reik, David I.K. Martin, Mark Groudine |
| Nuclear organization of DNA replication in primary mammalian cells. | Biological sciences | Brian K. Kennedy, David A. Barbie, Ed Harlow, Marie Classon, Nicholas Dyson |
| Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway. | Biological sciences | Eric Y. Huang, Jinsong Zhang, Eric A. Miska, Matthew G. Guenther, Tony Kouzarides, Mitchell A. Lazar |
| Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation. | Biological sciences | Michael Karin, Matthias Mann, Ching-Yi Chen, Roberto Gherzi, Jens S. Andersen, Guido Gaietta, Karsten Jurchott, Hans-Dieter Royer |
| Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK.(6-subunit core and a 3-subunit kinase)(Statistical Data Included) | Biological sciences | Sofia J. Araujo, Franck Tirode, Frederic Coin, Helmut Pospiech, Juhani E. Syvaoja, Manuel Stucki, Ulrich Hubscher, Jean-Marc Egly, Richard D. Wood |
| Orchestrated response: a symphony of transcription factors for gene control. | Biological sciences | Robert Tjian, Bryan Lemon |
| Osa-containing Brahma chromatin remodeling complexes are required for the repression of wingless target genes. | Biological sciences | Russell T. Collins, Jessica E. Treisman |
| p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells. | Biological sciences | V. Carrie Bromleigh, Leonard P. Freedman |
| p300-Mediated acetylation facilitates the transfer of histone H2A-H2B dimers from nucleosomes to a histone chaperone.(Statistical Data Included) | Biological sciences | Takashi Ito, Tsuyoshi Ikehara, Takeya Nakagawa, W. Lee Kraus, Masami Muramatsu |
| p53-independent functions of the p19(super.ARF) tumor suppressor. | Biological sciences | Guillermina Lozano, Jerold E. Rehg, Martine F. Roussel, Charles J. Sherr, Jason D. Weber, John R. Jeffers, David H. Randle, Gerard P. Zambetti |
| Pan-neural Prospero terminates cell proliferation during Drosophila neurogenesis. | Biological sciences | Ling Li, Harald Vaessin |
| PAT1, a new member of the GRAS family, is involved in phytochrome A signal transduction. | Biological sciences | Cordelia Bolle, Csaba Koncz, Nam-Hai Chua |
| Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye.(Statistical Data Included) | Biological sciences | Ruth Ashery-Padan, Till Marquardt, Xenlei Zhou, Peter Gruss |
| PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. | Biological sciences | Laura D. Attardi, Elizabeth E. Reczek, Corinna Cosmas, Elizabeth G. Demicco, Mila E. McCurrach, Scott W. Lowe, Tyler Jacks |
| Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. | Biological sciences | John L. Cleveland, Jodi R. Alt, Mark Hannink, J. Alan Diehl |
| Phosphorylation of histone H3 correlates with transcriptionally active loci.(Statistical Data Included) | Biological sciences | Scott J. Nowak, Victor Corces |
| Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition.(Statistical Data Included) | Biological sciences | Dale O. Cowley, Barbara J. Graves |
| Placental cell fates are regulated in vivo by HIF-mediated hypoxial responses. | Biological sciences | M. Celeste Simon, David M. Adelman, Marina Gertsenstein, Andras Nagy, Emin Maltepe |
| PML is induced by oncogenic ras and promotes premature senescence.(Statistical Data Included) | Biological sciences | Scott W. Lowe, Carol Prives, Gerardo Ferbeyre, Elisa De Stanchina, Emmanuelle Querido, Nicole Baptiste |
| pol(iota), a remarkably error-prone human DNA polymerase. | Biological sciences | Roger Woodgate, Agnes Tissier, John P. McDonald, Ekaterina G. Frank |
| Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements. | Biological sciences | Vincent Croquette, David Bensimon, Nancy J. Crisona, Terence Strick, Cozzarelli Cozzarelli |
| Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions.(messenger ribonucleoprotein particle) | Biological sciences | Herve Le Hir, Melissa J. Moore, Lynne E. Maquat |
| Pre-mRNA splicing in the absence of an SR protein RS domain. | Biological sciences | Jun Zhu, Adrian R. Krainer |
| Progression of meiotic DNA replication is modulated by interchromosomal interaction proteins, negatively by Spo11p and positively by Rec8p. | Biological sciences | Rita S. Cha, Beth M. Weiner, Scott Keeney, Job Dekker, N. Kleckner |
| Promoter opening by sigma(super.54) and sigma(super.70) RNA polymerases: sigma factor-directed alterations in the mechanism and tightness of control.(Statistical Data Included) | Biological sciences | Yuli Guo, Chih Min Lew, Jay D. Gralla |
| Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1.(Statistical Data Included) | Biological sciences | Galina Petukhova, Patrick Sung, Hannah Klein |
| Protein-protein interactions define specificity in signal transduction. | Biological sciences | Tony Pawson, Piers Nash |
| Proteolysis in Caenorhabditis elegans sex determination: cleavage of TRA-2A by TRA-3. | Biological sciences | Shareon B. Sokol, Patricia E. Kuwabara |
| P-TEFb kinase recruitment and function at heat shock loci. | Biological sciences | John T. Lis, Paul Mason, J. Peng, David H. Price, Janis Werner |
| Raf induces TGF(beta) production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells.(Statistical Data Included) | Biological sciences | Caroline S. Hill, Martin McMahon, Hartmut Beug, Kerstin Lehmann, Elzbieta Janda, Christophe E. Pierreux, Marjatta Rytomaa, Almut Schulze, Julian Downward |
| Rearrangement of chromatin domains during development in Xenopus. | Biological sciences | Marcel Mechali, Yegor Vassetsky, Alan Hair |
| RecA protein-dependent R-loop formation in vitro.(Statistical Data Included) | Biological sciences | Megumi Kasahara, Jennifer A. Clikeman, David B. Bates, Tokio Kogoma |
| RecE/RecT and Red(alpha)/Red(beta) initiate double-stranded break repair by specifically interacting with their respective partners.(Statistical Data Included) | Biological sciences | Joep P.P. Muyrers, Youming Zhang, Fraenk Buchholz, A. Francis Stewart |
| Reciprocal activation of Xenobiotic response genes by nuclear receptors SXR/PXR and CAR.(Statistical Data Included) | Biological sciences | Ronald M. Evans, Wen Xie, Joyce L. Barwick, Bruce Blumberg, Cynthia M. Simon, Philip S. Guzelian, Alexis M. Pierce, Stephen Safe |
| Regulation of cellular growth by the Drosophila target of rapamycin dTOR.(Statistical Data Included) | Biological sciences | Hongbing Zhang, James P. Stallock, Joyce C. Ng, Christoph Reinhard, Thoms P. Neufeld |
| Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXR(alpha) and LXR(beta). | Biological sciences | Michael S. Brown, Joseph L. Goldstein, Joyce J. Repa, Guosheng Liang, Jiafu Ou, Yuriy Bashmakov, Jean-Marc A. Lobaccaro, Iichiro Shimomura, Bei Shan, David J. Mangelsdorf |
| Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factors 1 alpha. | Biological sciences | Rajani Ravi, Bijoyesh Mookerjee, Zaver M. Bhujwalla, Carrie Hayes Sutter, Dmitri Artemov, Qinwen Zeng, Larry E. Dillehay, Ashima Madan, Gregg L. Semenza, Atul Bedi |
| Relief of gene repression by Torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning.(receptor tyrosine kinases) | Biological sciences | Gerardo Jimenez, Antoine Guichet, Anne Ephrussi, Jordi Casanova |
| Replication fork pausing and recombination or "gimme a break".(Statistical Data Included) | Biological sciences | Rodney Rothstein, Benedicte Michel, Serge Gangloff |
| Repression by Suppressor of Hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo.(Statistical Data Included) | Biological sciences | Veronique Morel, Francois Schweisguth |
| Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts.(Statistical Data Included) | Biological sciences | Zijian Guo, Akiko Kumagai, Sophie X. Wang, William G. Dunphy |
| Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus.(Statistical Data Included) | Biological sciences | Ueli Schibler, Francesca Damiola, Nguyet Le Minh, Nicolas Preitner, Benoit Kornmann, Fabienne Fleury-Olela |
| Retention of PDGFR-beta function in mice in the absence of phosphatidylinositol 3'-kinase and phospholipase Cgamma signaling pathways. | Biological sciences | Philippe Soriano, Michelle D. Tallquist, Richard A. Klinghoffer, Rainer Heuchel, Peter F. Mueting-Nelsen, Philip D. Corrin, Carl-Henrik Heldin, Richard J. Johnson |
| Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog Spitz.(transforming growth factor) | Biological sciences | Anne G. Bang, Chris Kintner |
| Ribosome shunting in the cauliflower mosaic virus 355 RNA leader is a special case of reinitiation of translation functioning in plant and animal systems. | Biological sciences | Thomas Hohn, Lyubov A. Ryabova |
| RNA polymerase II and the integration of nuclear events. | Biological sciences | Yutaka Hirose, James L. Manley |
| Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins.(Statistical Data Included) | Biological sciences | Sarah Jackson, Catherine Harwood, Miranda Thomas, Lawrence Banks, Alan Storey |
| Role of LXRs in control of lipogenesis.(liver X receptors) | Biological sciences | Joyce J. Repa, Bei Shan, David J. Mangelsdorf, Joshua R. Schultz, Hua Tu, Alvin Luk, Julio C. Medina, Leping Li, Susan Schwendner, Shelley Wang, Martin Thoolen, Kevin D. Lustig |
| Role of the rasGAP-associated docking protein p62(super.dok) in negative regulation of B cell receptor-mediated signaling.(Statistical Data Included) | Biological sciences | Yuji Yamanashi, Toshiki Tamura, Toshihide Kanamori, Hidehiro Yamane, Hideo Nariuchi, Tadashi Yamamoto, David Baltimore |
| Ro ribonucleoproteins contribute to the resistance of Deinococcus radiodurans to ultraviolet irradiation. | Biological sciences | Singuo Chen, Anne Marie Quinn, Sandra L. Wolin |
| Rules for DNA target-site recognition by a lactococcal group II intron enable retargeting of the intron to specific DNA sequences. | Biological sciences | Georg Mohr, Dorie Smith, Marlene Belfort, Alan M. Lambowitz |
| Severe liver degeneration and lack of NF-(kappa)B activation in NEMO/IKK(gamma)-deficient mice. | Biological sciences | Dorothea Rudolph, Wen-Chen Yeh, Andrew Wakeham, Bettina Rudolph, Dhani Nallainathan, Julia Potter, Andrew J. Elia, Tak W. Mak |
| Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers.(Statistical Data Included) | Biological sciences | Lingyang Zhu, Bill Wilken, Nelson G. Phillips, Umadevi Narendra, Ging Chan, Stephen M. Stratton, Stephen B. Kent, Michael A. Weiss |
| Side-branching in the mammary gland: the progesterone-Wnt connection. | Biological sciences | Gertraud W. Robinson, Lothar Henninghausen, Peter F. Johnson |
| Single mesodermal cells guide outgrowth of ectodermal tubular structures in Drosophila.(Statistical Data Included) | Biological sciences | Christian Wolf, Reinhard Schuh |
| Sip2p and its partner Snf1p kinase affect aging in S. cerevisiae.(Statistical Data Included) | Biological sciences | Kaveh Ashrafi, Stephen S. Lin, Jill K. Manchester, Jeffrey I. Gordon |
| Sir2 links chromatin silencing, metabolism, and aging.(silencing protein) | Biological sciences | Leonard Guarente |
| SPC4/PACE4 regulates a TFD(beta) signaling network during axis formation.(subtilisin-like proprotein convertases (SPCs)) | Biological sciences | Daniel B. Constam, Elizabeth J. Robertson |
| Spt5 and Spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster.(Statistical Data Included) | Biological sciences | Fred Winston, Craig D. Kaplan, James R. Morris, C.-ting Wu |
| Ssn6-Tup1 interacts with class I histone deactetylases required for repression.(Statistical Data Included) | Biological sciences | Sharon Y. Roth, Anjanette D. Watson, Diane G. Edmondson, James R. Bone, Yukio Mukai, Yaxin Yu, Wendy Du, David J. Stillman |
| Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix.(Statistical Data Included) | Biological sciences | G. Bruce Wisely, Millard H. Lambert, H. Eric Xu, Michael V. Milburn, Robert T. Gampe Jr., Valerie G. Montana |
| Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors.(Statistical Data Included) | Biological sciences | Nikola P. Pavletich, Philip D. Jeffrey, Lily Tong |
| Structure, function, and biology of SHIP proteins.(SH2-containing inositol 5'-phosphatase (SHIP)) | Biological sciences | Larry R. Rohrschneider, John F. Fuller, Ingrid Wolf, Yan Liu, David M. Lucas |
| Targeted disruption of the three Rb-related genes leads to loss of G(sub.1) control and immortalization.(Statistical Data Included) | Biological sciences | Laura D. Attardi, Tyler Jacks, Julien Sage, George J. Mulligan, Abigail Miller, SiQi Chen, Bart Williams, Elias Theodorou |
| Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.(Statistical Data Included) | Biological sciences | Bradley S. Cobb, Susana Morales-Alcelay, Gary Kleiger, Karen E. Brown, Amanda G. Fisher, Stephen T. Smale |
| tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c.(Statistical Data Included) | Biological sciences | Stanley J. Korsmeyer, Michael C. Wei, Tullia Lindsten, Vamsi K. Mootha, Solly Weiler, Atan Gross, Mona Ashiya, Craig B. Thompson |
| TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(sub)1 arrest. | Biological sciences | Claudia Petritsch, Hartmut Beug, Allan Balmain, Martin Oft |
| The alpha subunit of E. coli RNA polymerase activates RNA binding by NusA.(Escherichia coli)(Statistical Data Included) | Biological sciences | Thien-Fah Mah, Konstantin Kuznedelov, Arcady Mushegian, Konstantin Severinov, Jack Greenblatt |
| The bHLH regulator pMesogenin1 is required for maturation and segmentation of paraxial mesoderm. | Biological sciences | Jeong Kyo Yoon, Barabara Wold |
| The Caenorhabditis elegans APC-related gene apr-1 is required for epithelial cell migration and Hox gene expression. | Biological sciences | Erika Frohli Hoier, William A. Mohler, Stuart K. Kim, Alex Hajnal |
| The Caenorhabditis elegans fate-determining gene mab-9 encodes a T-box protein required to pattern the posterior hindgut. | Biological sciences | Jonathan Hodgkin, Alison Woollard |
| The carboxyl terminus of phage HK022 Nun includes a novel zinc-binding motif and a tryptophan required for transcription termination. | Biological sciences | Randolph S. Watnick, Stephanie Chiyoko Herring, Arthur G. Palmer III, Max E. Gottesman |
| The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing. | Biological sciences | Christine Vagner, Stephan Vagner, Iain W. Mattaj |
| The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast.(Statistical Data Included) | Biological sciences | Vera Paciotti, Michela Clerici, Giovanna Lucchini, Maria Pia Longhese |
| The coregulator exchange in transcriptional functions of nuclear receptors. | Biological sciences | Christopher K. Glass, Michael G. Rosenfeld |
| The Dlk1 and Gtl2 genes are linked and reciprocally imprinted.(Statistical Data Included) | Biological sciences | Shirley M. Tilghman, Jennifer V. Schmidt, Paul G. Matteson, Beverly K. Jones, Xiao-Juan Guan |
| The Drosophila Brahma complex is an essential coactivator for the trithorax group protein Zeste. | Biological sciences | Arnoud J. Kal, Tokameh Mahmoudi, Naomi B. Zak, C. Peter Verrijzer |
| The Drosophila HEM-2/NAP1 homolog KETTE controls axonal pathfinding and cytoskeletal organization. | Biological sciences | Thomas Hummel, Karin Leifker, Christian Klambt |
| The Drosophila Shark tyrosine kinase is required for embryonic dorsal closure.(SH2 domain ankyrin repeat kinase (SHARK)) | Biological sciences | Rafael Fernandez, Fumitaka Takahashi, Zhao Liu, Ruth Steward, David Stein, E. Richard Stanley |
| The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response.(Statistical Data Included) | Biological sciences | Randal J. Kaufman, Witoon Tirasophon, Kyungho Lee, Brian Callaghan, Ajith Welihinda |
| The forkhead domain gene unc-130 generates chemosensory neuron diversity in C. elegans. | Biological sciences | Trina R. Sarafi-Reinach, Piali Sengupta |
| The Forkhead transcription factor UNC-130 is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor in C. elegans. | Biological sciences | Bruce Nash, Antonio Colavita, Hong Zheng, Peter J. Roy, Joseph G. Culotti |
| The function of Xenopus Bloom's syndrome protein homolog (xBLM) in DNA replication. | Biological sciences | Hong Yan, Shuren Liao, Jeanine Graham |
| The glococorticoid receptor inhibits NF-kappa-B by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain.(Statistical Data Included) | Biological sciences | Keith R. Yamamoto, Robert M. Nissen |
| The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.(Statistical Data Included) | Biological sciences | Sheau-Yann Shieh, Jinwoo Ahn, Katsuyuki Tamai, Yoichi Taya, Carol Prives |
| The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1.(ubiquitin ligase, APC) | Biological sciences | Cathie M. Pfleger, Marc W. Kirschner |
| The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf. | Biological sciences | Weiquan Li, Min Han, Kun-Liang Guan |
| The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. | Biological sciences | John D. Alvarez, Dag H. Yasui, Hiroyuki Niida, Tadashi Joh, Dennis Y. Loh, Terumi Kohwi-Shigematsu |
| The mouse homolog of Drosophila Vasa is required for the development of male germ cells. | Biological sciences | Satomi S. Tanaka, Yayoi Toyooka, Ryuko Akasu, Yuko Katoh-Fukui, Yoko Nakahara, Rika Suzuku, Minesuke Yokoyam, Toshiaki Noce |
| The novel peptide HEADY specifies apical fate in a simple radially symmetric metazoan.(Statistical Data Included) | Biological sciences | Thomas C.G. Bosch, Jan U. Lohmann |
| The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies. | Biological sciences | Brian C. Freeman, Sara J. Felts, David O. Toft, Keith R. Yamamoto |
| The plasma membrane as a combat zone in the HIV battleground. | Biological sciences | Robert W. Doms, Didier Trono |
| The protein encoded by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication in a chromatin-specific manner.(Statistical Data Included) | Biological sciences | Matthias Mann, Vassilios Alexiadis, Tanja Waldmann, Jens Andersen, Rolf Knippers, Claudia Gruss |
| The Rb/E2F pathway: expanding roles and emerging paradigms.(Statistical Data Included) | Biological sciences | J. Wlliam Harbour, Douglas C. Dean |
| The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated Est1 protein.(Statistical Data Included) | Biological sciences | Virginia A. Zakian, Haiyan Qi |
| The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo. | Biological sciences | Tony Pawson, Ka-Man Venus Lai |
| The Something About Silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(sub II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. | Biological sciences | Sam John, LeAnn Howe, Stefan T. Tafrov, Patrick A. Grant, Rolf Sternglanz, Jerry L. Workman |
| The steroid receptor coactivator, GRIP-1, is necessary for MEF-2C-dependent gene expression and skeletal muscle differentiation. | Biological sciences | Shen Liang Chen, Dennis H. Dowhan, Brett M. Hosking, George E.O. Muscat |
| The stringent response in Myxococcus xanthus is regulated by SocE and the CsgA C-signaling protein. | Biological sciences | Eugene W. Crawford Jr., Lawrence J. Shimkets |
| The unfolded protein response represses nitrogen-starvation induced developmental differentiation in yeast.(Statistical Data Included) | Biological sciences | Randal J. Kaufman, Jason S. Chang, Martin Schroder |
| The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. | Biological sciences | Christian Frei, Susan M. Gasser |
| The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors. | Biological sciences | Yutaka Kikuchi, Le A. Trinh, Jeremy F. Reiter, Jonathan Alexander, Deborah Yelon, Didier Y.R. Stainier |
| The zinc ribbon domains of the general transcription factors TFIIB and Brf: conserved functional surfaces but different roles in transcription initiation. | Biological sciences | Steven Hahn, Sadia Roberts |
| Tissue- and stage-specific modulation of Wingless signalling by the segment polarity gene lines.(Statistical Data Included) | Biological sciences | Victor Hatini, Peter Bokor, Ryoko Goto-Mandeville, Stephen DiNardo |
| Transcriptional regulation of adipogenesis.(Statistical Data Included) | Biological sciences | Bruce M. Spiegelman, Evan D. Rosen, Christopher J. Walkey, Pere Puigserver |
| Transgene integration into the same chromosome location can produce alleles that express at a predictable level, or alleles that are differentially silenced. | Biological sciences | Christopher D. Day, Elsa Lee, Janell Kobayashi, Lynn D. Holappa, Henrik Albert, David W. Ow |
| Transgene-mediated cosuppression in the C. elegans germ line. | Biological sciences | Abby F. Dernburg, Jonathan Zalevsky, Monica P. Colaiacovo, Anne M. Villeneuve |
| Transient depletion of xDnmt1 leads to premature gene activation in Xenopus embryos.(Statistical Data Included) | Biological sciences | Irina Stancheva, Richard R. Meehan |
| Translational control of C/EBP(alpha) and C/EBP(beta) isoform expression.(Statistical Data Included) | Biological sciences | Cor F. Calkhoven, Christine Muller, Achim Leutz |
| Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA. | Biological sciences | Andrew Yueh, Robert J. Schneider |
| Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation.(Statistical Data Included) | Biological sciences | Robin A. Kimmel, Daniel H. Turnbull, Veronique Blanquet, Wolfgang Wurst, Cynthia A. Loomis, Alexandra L. Joyner |
| Two protein tyrosine phosphatases, PTp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast. | Biological sciences | Christopher P. Mattison, Irene M. Ota |
| Unified nomenclature for the winged helix/forkhead transcription factors. | Biological sciences | Klaus H. Kaestner, Walter Knochel, Daniel E. Martinez |
| Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle. | Biological sciences | Cristina Pelizon, Mark A. Madine, Piotr Romanowski, Ronald A. Laskey |
| Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans.(Statistical Data Included) | Biological sciences | Quinn M. Mitrovich, Philip Anderson |
| Ventral neural patterning by Nkx homeoNkx6.1 controls somatic motor neuron and ventral interneuron fates.(Statistical Data Included) | Biological sciences | Thomas M. Jessell, James Briscoe, Maike Sander, Sussan Paydar, Johan Ericson, Elizabeth Berber, Michael German, John L.R. Rubenstein |
| Where the cell cycle and histones meet.(Statistical Data Included) | Biological sciences | Mark E. Ewen |
| WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene.(Wnt-1-induced secreted protein 1(WISP-1)) | Biological sciences | Lifeng Xu, Ryan B. Corcoran, James W. Welsh, Diane Pennica, Arnold J. Levine |
| Wnt signaling and cancer.(Statistical Data Included) | Biological sciences | Paul Polakis |
| Wnt signaling maintains the hair-inducing activity of the dermal papilla. | Biological sciences | |
| Xenopus CDC7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading. | Biological sciences | J. Julian Blow, Pedro Jares |
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