Nature Medicine 2003 - Abstracts

Nature Medicine 2003
TitleSubjectAuthors
Accomplishments in HIV prevention science: implications for stemming the epidemic.HealthEugene McCray, Ronald O. Valdiserri, Lydia L. Odgen
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective.HealthDong Liu, John H. Griffin, Tong Cheng, Jose A. Fernandez, Francis Castellino, Elliot D. Rosen, Kenji Fukudome, Berislav V. Zlokovic
Activation and regulation of toll-like receptors 2 and 1 in human leprosy.HealthPatrick J. Brennan, Robert L. Modlin, Shizuo Akira, Peter A. Sieling, Thomas H. Rea, Stewart T. Cole, Euzenir N. Sarno, Michael V. Norgard, Stephan R. Krutzik, Maria Teresa Ochoa, Satoshi Uematsu, Yolanda W. Ng, Annaliza Legaspi, Philip T. Liu, Paul J. Godowski, Yumi Maeda
Adult mouse astrocytes degrade amyloid-beta in vitro and in situ.HealthTony Wyss-Coray, Fengrong Yan, Samuel C. Silverstein, John D. Loike, Thomas C. Brionne, Emily Lu, Roman Anankov, Jens Husemann
Advances in the use of synthetic combinatorial chemistry: mixture-based libraries.HealthClemencia Pinilla, Jon R. Appel, Eva Borras, Richard A. Houghten
Advantage of rare HLA supertype in HIV disease progression.HealthJohn Phair, Steven Wolinsky, Robert Funkhouser, Elizabeth Trachtenberg, Michael Fugate, Elizabeth Hayes, Bette Korber, Samuel Wu, Kevin Kuntsman, Yen S. Hsu, James Theiler, Cristina Sollars, Henry Erlich, Thomas B. Kepler, Peter T. Hraber
Akt helps stem cells heal the heart.HealthStanton L. Gerson, Omer N Koc
Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways.HealthBryan R.G. Williams, Robert H. Silverman, Wolfgang W. Leitner, Leroy N. Hwang, Michael J. deVeer, aimin Zhou, Thomas W. Dubensky, Han Ying, Nicholas Restifo
Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein.HealthVladimir Y. Bogdanov, Viji Balasubramanian, James Hathcock, Oana Vele, Mark Lieb, Yale Nemerson
An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice.HealthBarrett J. Rollins, Jayakrishna Ambati, Akshay Anand, Stefan Fernandez, Eiji Sakurai, Bert C. Lynn, William A. Kuziel, Balamurali K. Ambati
A new genetic method to generate and isolate small, short-lived but highly potent dendritic cell-tumor cell hybrid vaccines.HealthAndrew Bateman, Vy phan, Fiona Errington, Chiat Cheong, Tim Kottke, Michael Grough, Sharon Altmann, Annick Bradenburger, Steve Emery, Scott Strome, Bernard Bonnette, Alan Melcher, Richard Vile
Angiogenesis inhibitors: motivators of metastasis?.HealthPatricia S. Steeg
Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2.HealthRenhai Cao, Ebba Brakenhielm, Robert Pawliuk, David Wariaro, Mark J. Post, Eric Wahlberg, Philippe Leboulch, Yihai Cao
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects.HealthWolfram E. Samlowski, Ryan Petersen, Salvatore Cuzzocrea, Heather Macarthur, Damali Burton, John R. McGregor, Daniela Salvemini
A novel function for tissue inhibitor of metalloproteinases-3 (TMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2.HealthJian Hua Qi, Quteba Ebrahem, Nina Moore, Gillian Murphy, Lena Claesson-Welsh, Mark Bond, Andrew Baker, Bela Anand-Apte
A novel viral mechanism for dysregulation of beta-catenin in Kaposi sarcoma-associated herpesvirus latency .HealthFrederick Y. Wu, Masahiro Fujimuro, Colette apRhys, Henry Kajumbula, David B. Young, Gary S. Hayward, S. Diane Hayward
Anthrax delivers a lethal blow to host immunity.HealthMichael N. Starnbach, John R. Collier
Antiretroviral treatment for HIV infection in developing countries: an attainable new paradigm.HealthJ.P. Moatti, I. N'Doye, S.M. Hammer, P. Hale, M. Kazatchkine
Anti-steroid takes aim at neuropathy.HealthPeter De Jonghe, Vincent Timmerman
A peptide inhibitor of c-Jun N-terminal kinase proyects against excitotoxicity and cerebral ischemia.HealthJulien Bogousslavsky, Peter G.H. Clarke, Tiziana Borsello, Lorenz Hirt, Alessandro Vercelli, Mariaelena Repici, Daniel F. Schorderet, Christophe Bonny
Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis.HealthStefan H.E. Kaufmann, Peter A. Sieling, Volker Brinkmann, Ulrich E. Schaible, Florian Winau, Karsten Fischer, Helen L. Collins, Hagens, Kristine ;
A prion protein epitope selective for the pathologically misfolded conformation.HealthParamithiotis, Eustache; Zuo, Wan-Quan;, Pinard, Mark; Francoeur, Gregory P.; Pap, Lawton, Trebor; Head, Mark; Will, Robert;, LaBoissiere, Sylvie; Tonelli, Quentin; Led, Valerie L. Leathers
A role for nonprotective complement-fixing antibodies with low avidity for measles virus in atypical measles.HealthFernando P. Polack, Diane E. Griffin, Scott J. Hoffman, Gonzalo Grujeiras
Attacking pain at its source: new perspectives on opioids.HealthChristoph Stein, Michael Schafer, Halina Machelska
Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function.HealthHolger Stark, Pierre Sokoloff, Erwan Bezard, Sandrine Ferry, Ulrich Mach, Ludovic Leriche, Thomas Boraud, Christian Gross
Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion.HealthRebecca P. Haberman, Jude R. Samulski, Thomas J. McCown
Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice.HealthTasuku Honjo, Akira Mizoguchi, Jian Wang, Taku Okazaki, Yoshimasa Tanaka, Ryosuke Nishio, Tamotsu Mitsuiye, Masayoshi Ishida, Hiroshi Hiai, Matsumori, Akira;, Nagahiro Minato
Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive.HealthPere Santamaria, Dorothy J. Becker, Shawn Winer, Hubert Tsui, Ambrose Lau, Aihua Song, Xiaomao Li, Roy K. Cheung, Anastazia Sampson, Fatemeh Afifiyan, Alisha Elford, George Jackowski, Pamela Ohashi, H.-Michael Dosch
Autoimmunity: busting the atherosclerotic plaque.HealthNoel Rose, Marina Afanasyeva
Autoimmunity heats up.HealthAndrew E. Gleman, Laurence A. Turka
B cell memory: sapping the T cell.HealthRaymond M. Welsh, Eva Szomolanyi-Tsuda, Susan E. Stepp
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy.HealthDiane Edelstein, Takeshi Matsumura, Hans-Peter Hammes, Ida Giardino, Michael Brownlee, Xueliang Du, Angelika Bierhaus, Tetsuya Taguchi, Qida Ju, Jihong Lin, Peter Nawroth, Dieter Hannak, Michael Neumaier, Regine Bergfeld
Beta(sub)1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure.HealthLynne E. Wagoner, Stephen B. Liggett, Jeanne Mialet Perez, Deborah A. Rathz, Natalia N. Petrashevskaya, Harvey S. Hahn, Arnold Schwartz, Gerald W. II Dorn
Beyond six colors: a new era in flow cytometry.HealthStephen C. De Rosa, Jason M. Brenchley, Mario roederer
Biological drug duo delivers one-two tumor punch.HealthJames W. Mier, Jeffrey A. Sosman
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity.HealthLieping Chen, David T. Curiel, Weiping Zou, Shuang Wei, Roman Krzysiek, Alan Gordon, Dominique Emilie, Tyler J. Curiel, Haidong Dong, Xavier Alvarez, Pui Cheng, Peter Mottram, Keith L. Knutson, Ben Daniel, Maria Carla Zimmermann, Odile David, Matthew Burow, Nina Dhurandhar, Leann Myers, Ruth Berggren, Akseli Hemminki, Ronald D. Alvarez
BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect.HealthRichard G. Ellenbogen, James M. Olson, Roshantha A.S. Chandraratna, Andrew R. Hallahan, Joel I. Pritchard, J. Russel Geyer, Ryan P. Overland, Andrew D. Strand, Stephen J. Tapscott
BMP-7 counteracts TGF-beta1- induced epithelial-to-mesenchymal transition and reverses chronic renal injury.HealthMichael Zeisberg, Jun Ichi Hanai, Hikaru Sugimoto, Tadanori Mammoto, David Charytan, Raghu Kalluri, Frank Strutz
Bone marrow as a priming site for T- cell responses to blood-borne antigenl.HealthBruno Kyewski, Andreas Limmer, Markus Feuerer, Philipp Beckhove, Volker Schirrmacher, Natalio Garbi, Yolanda Mahnke, Mirja Hommel, Gunter J Hammerling, Alf Hamann, Viktor Umansky
Building the translational highway: toward new partnerships between academia and the private sector.HealthKetty Schwartz, Jean-Thomas Vilquin
Building up the blood-brain barrier.HealthPeter Rieckmann, Britta Engelhardt
Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland.HealthMichael D. Johnson, Robert Clarke, Bruce Trock, Nicholas Kenney, Adriana Stoica, Leena Hilakivi-Clarke, Baljit Singh, Gloria Chepko, Peter F. Sholler, Apolonio A. Lirio, Colby Foss, Ronald Reiter, Soonmyoung Paik Paik, Mary Beth Martin
Cadmium's disguise dupes the estrogen receptor.HealthStephen Safe
Cancer fears stall trails for testosterone replacement.HealthLaura Bonetta
Can needle-free administration of vaccines become the norm in global immunization?.HealthMyron M. Levine
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury.HealthR. Neal Smith, Fang Liu, Leo E. Otterbein, Fritz H. Bach, Augustine M.K. Choi, Timothy R. Billiar, Brian S. Zuckerbraun, Manabu Haga, Ruiping Song, Anny Usheva, Christiana Stachulak, Natalya Bodyak, Eva Csizmadia, Shivraj Tyagi, Yorihiro Akamatsu, Richard J. Flavell, Edith Tzeng, Miguel P. Soares
CD46 is a cellular receptor for group B adenoviruses.HealthAndre Lieber, Anuj Gaggar, Dmitry M. Shayakhmetov
CD4+CD25+ regulatory T cells preserve graft-versus-tumor captivity while inhibiting graft-versus-host disease after bone marrow plantation.HealthSamuel Strober, Mathias Edinger, Petra Hoffmann, Joerg Ermann, Kathryn Drago, C Garrison Fathman, Robert S. Nergin
Cell encapsulation: promise and progress.HealthA.M. James Shapiro, Paul De Vos, Gorka Orive, Rosa Maria Hernandez, Alicia R. Gascon, Riccardo Califiore, Thomas M.S. Chang, Gonzalo Hortelano, David Hunkeler, Igor Lacik, Jose Luis Pedraz
Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo.HealthWilliam C. Sessa, Jean-Philippe Gratton, Jun Yu, Jason W. Griffith, Roger W. Babbitt, Ramona S. Scotland, Reed Hickey, Frank J. Giordano
Chromosomal translocation products engender new intracellular therapeutic technologies.HealthTerence H. Rabbitts, Martin Stocks
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.HealthDan R. Littman, Steffen Jung, Klaus Ley, David F. Smith, Yuqing Huo, Andreas Schober, S. Bradley Forlow, Matthew Craig Hyman, Christian Weber
Clonality analysis after retroviral-mediated gene transfer to CD34(sup)+ cells from the cord blood of ADA-deficient SCID neonates.HealthManfred Schmidt, Carbonaro Denise A., Carsten Speckmann, Manuela Wissler, John Bohnsack, Melissa Elder, Bruce J. Aronow, Jan A. Nolta, Donald B. Kohn, Christof Von Kalle
Clonal vaccinia virsus grown in cell culture as a new smallpox vaccine.HealthThomas P. Monath, Richard Weltzin, Jian Liu, Konstantin V. Pugachev, Gwendolyn A. Myers, Coughlin, Brie ; Blum, Paul S., Jeffrey S. Kennedy, Francis A. Ennis, John Cruz, Casey Johnson, Richard Nichols
Coaxing coagulation with RNA and cell fragments.HealthKatherine A. High
Contribution of hematopoietic stem cells to skeletal muscle.HealthHelen M. Blau, Stephane Y. Corbel, Adrienne Lee, Lin Yi, Jeffery Duenas, Timothy R. Brazelton, Fabio M.V. Rossi
Control of osteoblast function and regulation of bone mass.HealthShun-ichi Harada, Gideon A. Rodan
CpG motifs: the active ingredient in bacterial extracts?.HealthArthur M. Kreig
Cranial skeletal biology.HealthJ. A. Helms, R. A. Schneider
Cyclophilin A modulates The sensivity of HIV-1 to host restriction factors.HealthJeremy Luban, Paul D. Bieniasz, Stephen P. Goff, Greg J. Towers, Theodora Hatziioannou, Simone Cowan
Cytokine traps: multi-component, high-affinity blockers of cytokine action.HealthJohn S. Rudge, George D. Yancopoulos, Frank Lee, Aris N. Economides, Laura Rocco Carpenter, Vivien Wong, Ellen M. Koehler-Stec, Christopher Hartnett, Erica A. Pyles, Xiaobing Xu, Thomas J. daly, Michael R. Young, James P. Fandl, Scott Carver, Jennifer McNay, Kevin Bailey, Swayampakula Ramakanth, Renta Hutabarat, Tammy T. Huang, Czeslaw Radziejewski, Neil Stahl
Deciphering skeletal patterning: clues from the limb.HealthGail R. Martin, Francesca V. Mariani
Deletion of cytosolic phospholipase A2 promotes striated muscle growth.HealthBrian Walters, Xin Chen, Anthony Rosenzweig, Syed Haq, Kaushik Battacharya, Xio Ming Sun, Heiko Kilter, Michele Andreucci, Lei Cui, Ashour Michael, Jeffery Molkentin, Ronglih Liao, Richard Pattern, Luis J. Guerrero, Jingzang Toa, Thomas Force, Joseph V Bonventre, Michael Picard, Eileen O'Leary
Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity.HealthKurt Bachmaier, Josef Penninger, Lukas Hunziker, Manfred Kopf, Romeo Ricci, Gavin Y. Oudit, Urs Eriksson, Michael O. Kurrer, Tania H. Watts, Ivo Sonderegger
Dengue immune response: low affinity, high febrility. .HealthRaymond M. Welsh, Alan L. Rotham
Detection of virus-specific T cells and CD8(sup)+ T-cell epitopes by acquisition of peptide-HLA-GFP complexes; analysis of T-cell phenotype and fnction in chronic viral infections.HealthSteven Jacobson, Utano Tomaru, Yoshihisa Yamano, Masahiro Nagai, Dragan Maric, Previn T.P. Kaumaya, William Biddison
Developmental regulation of the growth plate.HealthHenry M. Kronenberg
Dexamethasone induction of hypertention and diabetes is PPAR-alpha dependent in LDL receptor-null mice.HealthTrey Coleman, Clay F. Semenkovich, Carlos Bernal-Mizrachi, Sherry Weng, Chu Feng, Brain N. Finck, Russell H. Knutsen, Teresa C. Leone, Daniel P. Kelly, Robert P Mecham
Differential requirement for CD8 in T-helper effector homing.HealthArthur L. Beaudet, Seung-Hyo Lee, Joseph E. Prince, Muhammad Rais, Farrah Kheradmand, Felix Shardonofsky, Huifang Lu, C. Wayne smith, Lynn Soong, David B. Corry
Dilated cardiomyopathy: learning to live with yourself.HealthRobb W. MacLellan, Aldons L. Lusis
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease.HealthDavid J. Brooks, Peter Heywood, Steven S. Gill, Nikunj K. Patel, Gary R. Hotton, Karen O'Sullivan, Renee McCarter, Martin Bunnage, Clive N. Svendsen
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors.HealthHans Joenje, Toshiyasu Taniguchi, Marc Tischkowitz, Najim Ameziane, Shirley V. Hodgson, Christopher G. Mathew, Samuel C. Mok, Andrea D Alan D.
Duration of antiviral immunity after smallpox vaccination.HealthErika Hammarlund, Mathew W. Lewis, Scott G. Hansen, Lisa I. Strelow, Jay A. Nelson, Mark K. Slifka, Jon M. Hanifin, Gary J. Sexton
Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation.HealthRakesh K. Jain, Edward Brown, Trevor McKee, Emmanuelle diTomaso, Alain Pluen, Brian Seed, Yves Boucher
eLixiRs for restraining inflammation.HealthMason W. Freeman, Kathryn J. Moore
Endothelial signaling during development.HealthDouglas A. Melton, Ondine Cleaver
Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury.HealthMarkus Stoffel, Alla Khodorova, Betsy Navarro, Laurence Sophie Jouaville, Jo-Ellen Murphy, Frank L. Rice, Joseph E. Mazurkiewicz, Denise Long-Woodward, Gary R. Strichartz, Rus Yukhananov, Gudarz Davar
Engineered antibodies.HealthPeter J. Hudson, Christelle Souriau
Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans.HealthKaren Brown, Robert E. Sinden, Samuel J. McConkey, William H H. Reece, Vasee S. Moorthy, Daniel Webster, Susanna Dunachie, Geoff Butcher, Jenni M. Vuola, Tom J. Blanchard, Philip Gothard, Kate Watkins, Carolyn M. Hanman, Simone Everaere, Kent E. Kester, James Cummings, Jackie Williams, D Gray Heppner, Ansar Pathan, Katie Flanagan, Mark T. M. Roberts, Nirmala Arunlanathamn, Michael Roy, Geoffrey L. Smith, Joerg Schneider, Tim Peto, Sarah C. Gilbert, Adrian V. S. Hill
Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells.HealthJoel M. Palefsky, Sharof M. Tugizov, Jennifer W. Berline
Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.HealthJean-Baptiste Latouche, Michel Sadelain, Renier J. Brentjens, Elmer Santos, Francesc Marti, Michael C. Gong, Clay Lyddane, Philip D. King, Steven Larson, Mark Weiss, Isabelle Riviere
Erythrpoietin may impair, not improve, cancer survival.(Antineoplastic agents)HealthVicki Brower
Escherichia coli gets the message.HealthKlaus Winzer, Paul Williams
Essential role of endothelial intric oxide synthase for mobilization os stem and progenitor cells.HealthChristopher Heeschen, Stefanie Dimmeler, Andreas M. Zeiher, Alexandra Aicher, Christiane Mildner-Rihm, Carmen Urbich, Christian Ihling, Technau-Ihling
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity.HealthMichael J. Grusby, Mitchell Kronenberg, Toshinori Nakayama, Masaru Taniguchi, Omid Akbari, Philippe Stock, Everett Meyer, Stephane Sidobre, Rosemarie H. DeKruyff, Dale T. Umtsu
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase.HealthCatherine Uyttenhove, Luc Pilotte, Ivan Theate, Vincent stroobant, Didier Colau, Nicolas Parmentier, Thierry Boon, Benoit J. Van den Eynde
Evolving concepts of rheumatoid arthritis.HealthGary S. Firestein
Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein.HealthPierre Charneau, Paul-Henri Romeo, Sophie Amsellem, Francoise Pflumio, Dominique Bardinet, Brigitte Izac, Anne Dubart-Kupperschmitt, Serge Fichelson
Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.HealthPeter P. Lee, Michael R. Betts, Mario Roederer, Valerie Rubio, Tor B. Stuge, Naileshni Singh, Jeffrey S. Weber
Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells.HealthCarl H. June, Mathias Oelke, Marcela V. Maus, Dominic Didiano, Andreas Mackensen, Jonathan P. Schneck
F(ab)'(sub)2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins.HealthCarl R. Alving, Michael C. Carroll, Stanko S. Stojilkovic, Dean D. Metcalfe, Milan Basta, Fredric Van Goor, Stefano Luccioli, Eric M. Billings, Alexander O. Vortimeyer, Lajos Baranyi, Janos Szeben, Ira Berkower
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade.HealthElizabeth Inchbald, Steven H. Sacks, Nicola J. Monk, Roseanna E.G. Hargreaves, James E. Marsh, Conrad A. Farrar, Maggie Millrain, Julian Dyson, Stipo Jurcevic
Fertility's new frontier takes shape in the test tube.HealthApoorva Mandavalli
Fishy asthma cure raises big stink in India.HealthK.S. Jayaram
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse.HealthGlenn E. Morris, Qi Long Lu, Christopher J. Mann, Fang Lou, George Bou-Gharios, Shao-an Xue, Sue Fletcher, Terence A. Partridge, Stephen D. Wilton
Genetic deficiency in Pparg does not alter development of experimental prostate cancer.HealthRonald M. Evans, Enrique Saez, Peter Olson
Gene transfer as a tool to induce therapeutic vascular growth.HealthSeppo Yla-Herttuala, Kari Alitalo
Geographic diversity and temporal trends of antimicrobial resistance in Streptococcus pneumoniae in the United States.HealthMonica M. Farley, Lee H. Harrison, William Schaffner, Cynthia G. Whitney, James Hadler, Arthur Reingold, Nancy M. Bennett, Ruth Lynfield, Althea W. McCormick, Paul Cieslak, Matthew H. Samore, Marc Lipsitch
Glucagons-like peptide-1 receptor is involved in learning and neuroprotection.HealthMatthias Klugmann, Daniel J. Drucker, Mathew J. During, Cao Lei, David S. Zugga, Jeremy S Francis, Helen L. Fitzsimons, Ross J. Bland, Xiangyang Jiao, Colin N. Haile, William A. Banks
Gradual adaptation of HIV to human host populations: good or bad news?.HealthBruce D. Walker, Christian Brander
Grey-lethal mutation induces severe malignant autosomal recessive osteoporosis in mouse and human.HealthNader Chalhoub, Nadia Benachenhou, Venkatesh Rajapurohitam, Monica Pata, Mathieu Ferron, Annalisa Frattini, Anna Villa, Jean Vacher
G(sub)13 is an essential mediator of platelet activation in hemostasis and thrombosis.HealthMelvin I. Simon, Nina Wettschureck, Stefan Offermanns, Alexandra Moers, Bernhard NIeswandt, Steffen Massberg, Sabine Gruner, Ildiko Konrad, Valerie Schulte, Barsom aktas, Marrie-Pierre Gratacap, Meinrad Gawaz
Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity.HealthWijnand Eling, Michel Prenant, Olivier Silvie, Eric Rubinstein, Jean-Francois Franetich, Elodie Belnoue, Laurent Renia, Laurent Hannoun, Shoshana Levy, Claude Boucheix, Dominique Mazier
Hepatocyte growth factor and its receptor are required for malaria infection.HealthAna Rodriguez, Margarida Carrolo, Silvia Giordano, Laura Cabrita-Santos, Simona Corso, Ana M. Vigario, Susana Silva, Patricia Leiriao, Daniel Carapau, Rosario Armas-Portela, Paolo M. Comoglio, Maria M. Mota
HIV-1 infection: fooling the gatekeeper.HealthBryan R. Cullen
HIV-1 pathogenesis.HealthMario Stevenson
HIV-1 tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.HealthQian Huang, Richard A. Young, Elena Izmailova, Frederic M.N. Bertley, Norbert Makori, Christopher J. Miller, Anna Aldovini
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation.HealthMariana Marin, Kristine M. Rose, Susan L. Kozak, David Kabat
HIV and AIDS: 20 years of science.HealthAnthony S. Fauci
HIV and AIDS: looking ahead.HealthRobin A. Weiss
HIV vaccines 1983-2003.HealthTomas Hanke, Andrew J. McMichael
Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts.HealthJ. Berger, H. Grassme, V. Jendrossek, A. Riehle, G. von Kurthy, H. Schwarz, M. Weller, R. Kolesnick, E. Gulbins
How to Win the Noble Prize: An Unexpected Life in Sciences by Bishop, J. Michae.(Book Review)HealthPaul Greengard
Hsp 70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo.(heat-shock proteins)HealthPamela S. Ohashi, Nobuyuki Ono, Bernhard Odermatt, Douglas G. Millar, Kristine M. Garza, Alisha R. Elford, Zihai Li
Hugo Barrera-Saldana.HealthHelen Pearson
Human and porcine early kidney precursors as a new source for transplantation.HealthYair Reisner, Benjamin Dekel, Tatyana Burakova, Fabian D. Arditti, Shlomit Reich-Zeliger, Oren Milstein, Sarit Aviel-Ronen, Gideon Rechavi, Nir Friedman, Naftali Kaminski, Justen H. Passwell
Human susceptibility and resistance to Norwalk virus infection.HealthXi Jiang, Lisa Lindesmith, Christine Moe, Severine Marionneau, Nathalie Ruvoen, Lauren Lindblad, Paul Stewart, Jacques LePendu, Ralph Baric
IBM accused of ignoring employee 'cancer cluster'.HealthKristine Novak
Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain.HealthNeeta Singh Roy, Jian Kang, Maiken Nedergaard, Steven A. Goldman, Marta C. Nunes, H. Michael Keyoung, Robert R. Goodman, Guv McKhann, Li Jiang
Identification of PDGFR as a receptor for AAV-5 transduction.HealthGiovanni Di Pasquale, Beverly L. Davidson, Colleen S. Stein, Ines Martins, Dominic Scudiero, Anne Monks, John A. Chiorini
Imaging 26S proteasome activity and inhibition in living mice.HealthGary D. Luker, Christina M. Pica, Jiling Song, Kathryn E. Luker, David Piwnica-Worms
Imaging of angiogenesis: from microscope to clinic.HealthDonald M. McDonald, Peter L. Choyke
Immunopathogenesis and immunotherapy in AIDS virus infection.HealthNorman L. Letvin, Bruce D Walker
Immunotherapy for AIDS virus infections: cautious optimism for cell-based vaccine.HealthBruce D. Walker, Nina Bhardwaj
Immunotherapy of established tumors using bone marrow transplantation with antigen gene-modified hematopoietic stem cells.HealthYan Cui, Curt I Civin, Ivan Borrello, Hyam Levitsky, Erin. Kelleher, Stephen P. Schoenberger, Erin Straley, Drew M. Pardoll, Linzhao Cheng, Ephraim Fuchs, Katharine A. Whartenby, Kevin Gorski
Immunotherapy: past, present and future.HealthThomas A. Waldmann
Inflammation and cancer.(Nature insight reviews)HealthZena Werb, Lisa M. Coussens
Inflammation and therapeutic vaccination in CNS diseases.(Nature insight reviews)HealthDennis J. Selkoe, Howard L. Weiner
Inflammation in atherosclerosis.(Nature insight reviews)HealthPeter Libby
Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production.HealthSilvana Obici, Zhaohui Feng, Ardunio Arduini, Roberto Conti, Luciano Rossetti
Inhibition of renal cystic disease development and progression by a vasopressin V2receptor antagonist.HealthVicente E. Torres, Peter C. Harris, Vincent H. II Gattone, Xiaofang Wang
Inositol- and folate-resistance neural tube defects in mice lacking the epithelial-specific factor Grhl-3.HealthTim Thomas, Mark Hall, Stephen B. Ting, Tomasz Wilanowski, Alana Auden, Anne K. Voss, Vishwas Parekh, John M. Cunningham, Stephen M. Jane
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogeneous leukemia.HealthTakuya Matsunga, Naofumi Takemoto, Tsutomu Sato, Rishu Takimoto, Ikuta Tanaka, Akihito Fujimi, Takehide Akiyama, Hiroyuki Kuroda, Yukata Kawano, Masayoshi Kobune, Junji Kato, Yasuo Hirayama, Sumio Sakamaki, Kyuhei Kohda, Kensuke Miyake, Yoshiro Niitsu
Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.HealthRaymond T. Camphausen, Denisa D. Wagner, Beatrice Cambien, Rodger P. McEver, Ingrid Hrachovinova, Ali Kappelmayer Hafezi-Moghadam Janos, Angela Widom, Lijun Xia, Haig H. Jr. Kazazian, Robert G. Schaub
Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease.HealthMatthias Mack, Detlef Schlondorff, Gerd Plewig, Martin Rocken, Kamran Ghoreschi, Peter Thomas, Susanne Breit, Martin Dugas, Reinhard Mailhammer, Willem van Eden, Ruurd van der Zee, Tilo Biedermann, Jorg Prinz, Ulrich Mrowietz, Enno Christophers, Christian A. Sander
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein.HealthR. Keith Humphries, Guy Sauvageau, Jana Krosl, Pamela Austin, Nathalie Beslu, Evert Kroon
In vivo imaging of transcriptionally active estrogen receptors.HealthPaolo Ciana, Michele Raviscioni, Paola Mussi, Elisabetta Vegeto, Ivo Que, Malcolm G. Parker, Clemens Lowik, Adriana Maggi
In vivo imaging reveals estrogen receptor's hidden personality.HealthGeoffrey L. Greene
Ion implicated in blood pact.HealthDavid A. Wink
JAKing up immunosuppression.HealthMegan Sykes
Kari Stefansson.HealthHelen Pearson
Keeping the lock on smallpox.HealthDavid B. Weiner
Lamin mutations come of age.HealthRobert A. Hegele
Learning from the gut.HealthMark P. Mattson, TracyAnn Perry, Nigel Greig
Letting antibodies get to your head.HealthRobert S. Fujinami, Thayne L. Sweeten
Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease.HealthSusumu Ishida, Kenji Yamashiro, Tomohiko Usui, Yuichi Kaji, Yuichiro Ogura, Tetsuo Hida, Yoshihito Honda, Yoshihisa Oguchi, Anthony P. Adamis
Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy.HealthMasahisa Katsuno, Hiroaki Adachi, Manabu Doyu, Makoto Minamiyama, Chen Sang, Yasushi Kobayashi, Gen Sobue, Inukai, Akira;
Ligand-directed targeting of genes to the site of disease.HealthTomas J. Wickham
Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.HealthXiaoying Wang, Sun-Ryung Lee, Ken Arai, Seong-Ryong Lee, Kiyoshi Tsuji, G. William Rebeck, Eng H. Lo
Local gene knockdown in the brain using viral-mediated RNA interference.HealthJonathan D. Hommel, Robert M. Sears, Dan Georgescu, Diana L. Simmons, Ralph J. DiLeone
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.HealthThomas C. Quinn, Robert F. Siliciano, Diana Finzi, Stephen J. Gange, Joseph B. Margolick, Janet D. Siliciano, Colin Kovacs, Joleen Kajdas, Karen Chadwick
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomypathy.HealthFayez Dawood, Arnold Schwartz, Peter P. Liu, Gavin Y. Oudit, Hui Sun, Maria G. Trivieri, Sheryl E. Koch, Cameron Ackerley, Mehrdad Yazdanpanah, Greg J Wilson, Peter H. Backx
Marrow to muscle, fission versus fusion.(bone marrow cells )HealthMichael A. Rudnicki
Mary-Claire King.(Geneticists)HealthCharlotte Schubert
Mast cells in autoimmune disease.(Nature insight reviews)HealthChristophe Benoist, Diane Mathis
Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing.HealthWilliam J. Bowers, Howard J. Federoff, Jennifer E. Snyder, Alexandra M. Livingstone, F. Eun-Hyung Lee, Tim R. Mosmann
Melusin, a muscle-specific integrin beta(sub)1--interacting protein, is required to prevent cardiac failure in response to chronic pressure overload.HealthGennaro Marino, Mara Brancaccio, Luigi Fratta, Antonella Notte, Emilio Hirsch, Roberta Poulet, Simona Guazzone, Marika De Acetis, Carmine Vecchione, Fiorella Altruda, Lorenzo Silengo, Guido Tarone, Giuseppe Lembo
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infracted hearts.HealthVictor J. Dzau, Abeel A. Mangi, Nicolas Noiseux, Deling Kong, Huamei He, Mojgan Rezvani, Joanne S Ingwall
Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea.HealthSusan E. Swedo, Christine A Kirvan, Janet S. Heuser, Madeleine W. Cunningham
Modulation of anxiety through blockade of anandamide hydrolysis.HealthDaniele Piomelli, Satish Kathuria, Silvana Gaetani, Darren Fegley, Fernando Valino, Andrea Duranti, Andrea Tontini, Marco Mor, Giorgio Tarzia, Giovanna La Rana, Antonio Calignano, Arcangela Giustino, Maria Tattoli, Maura Palmery, Vincenzo Cuomo
Molecular regulation of vessel maturation.HealthRakesh K. Jain
Monitoring photodynamic therapy of solid tumors online by BOLD-contrast MRI.HealthAvigdor Scherz, Shimon Gross, Assaf Gilead, Michal Neeman, Yoram Salomon
Multiple actions of systemic artemin in experimental neuropathy.HealthSusan F. Foley, Luis R. Gardell, Ruizhong Wang, Chris Ehrenfels, Michael H. Ossipov, Anthony J. Rossomando, Stephan Miller, Carolyn Buckley, Amber K. Cai, Albert Tse, Banglian Gong, Lee Walus, Paul Carmillo, Dane Worley, Carol Huang, Thomas Engber, Blake Pepinsky, Richard L. Cate, Todd W. Vanderah, Josephine Lai, Dinah W.Y. Sah, Frank Porreca
Murder mysteries in type 1 diabetes.HealthDaniel L. Kaufman
Muscle-specific Pparg deletion causes insulin resistance.HealthRonald M. Evans, Yaacov Barak, Peter Olson, Andrea L. Hevener, Weimin He, Jamie Le, Gautam Bandyopadhyay, Jason Wilkes, Jerrold Olefsky
Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8(sup)+ T-cell responses.HealthMarina Botto, James Alexander, Simona Stager, Alun C. Kirby, Nico Van Rooijen, Deborah f. smith, Frank Brombacher, Paul M. Kaye
Natural-born killers.(herbal supplements)HealthApoorva Mandavilli
NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice.HealthHideto Kojima, Mineko Fujimiya, Kazuhiro Matsumura, Patrick Younan, Hirotsugu Imaeda, Makiko Maeda, Lawrence Chan
Neuropathology of human alzheimer disease after immunization with amyloid-beta peptide: a case report.HealthDavid Wilkinson, James A.R. Nicoll, Clive Holmes, Phil Steart, Hannah Markham, Roy O. Weller
NIH privatization push compromising science, critics warn.(National Institutes of Health)HealthTinker Ready
Nitric oxide's reactions with hemoglobin: a view through the SNO-storm.HealthAlan N. Schechter, Mark T. Gladwin, Jack R. Jr. Lancaster, Bruce A. Freeman
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation.HealthAlan N. Schechter, Mark T. Gladwin, Kenyatta Cosby, Kristine S. Partovi, Jack H. Crawford, Rakesh P. Patel, Christopher D. Reiter, Sabrina Martyr, Benjamin K. Yang, Myron A. Waclawiw, Gloria Zalos, Xiuli Xu, Kris T. Huang, Howard Shields, Daniel B. Kim-Shapiro, Richard O. III Cannon
Novel strategies for the treatment of sepsis.HealthPeter A. Ward, Niels C. Riedemann, Ren-Feng Guo
Nurses disappearing from developing nations.HealthCharlotte Schubert
Old debates rekindled as world AIdS rates escalate.HealthMyrna Watanabe
Orchestrating sleep-wake functions in the brain.HealthGoran Hajak, Peter Geisler
Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever.HealthAndrew McMichael, Juthathip Mongkolsapaya, Siraporn Sawasdivorn, Aroonrung Chairunsri, Wanwisa Dejnirattisai, Tao Dong, Thaneeya Duangchinda, Xiao-ning Xu, Pa-thai Yenchitsomanus, Sarah Roland Jones, Sirijitt Vasanawathana, Gavin Screaton, Prida malasit, Nattaya Tangthawornchaikul
Osteoclast differentiation and activation.HealthDavid L. Lacey, William J. Boyle, W. Scott Simonet
Pediatric drug testing enters infancy.HealthJenette Restivo
Permanent correction of an inherited ectodermal dysplasia with recombinant EDA.HealthOlivier Gaide, Pascal Schneider
Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer.HealthZvi Fuks, Carlos Cordon-Cardo, H. Rosie Xing, Xinzhu Deng, William Tong, Luis Campodonico, Richard Kolesnick
Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing.HealthHengjun Chao, Gary S. Mansfield, Robert C. Bartel, Suja Hiriyanna, Lloyd G. Mitchell, Mariano A. Garcia-Blanco, Christopher E. Walsh
Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas.HealthSusan E. Crawford, Jennifer A. Doll, Veronica M. Stellmach, Noel P. Bouck, Anders Rj Bergh, Michael R. Pins, Mona L. Cornwell, Lisa P. Abramson, Lee, Chung;, Jayme Borensztajn
Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in himan populations.HealthAlan F. Cowman, John C. Reeder, Alexander G. Maier, Manoj T. Duraisingh, Sheral S. Patel, James W. Kazura, Peter A. Zimmerman
Pluripotent stem cells from the adult mouse inner ear.HealthHong Liu, Stefan Heller, Huawei Li
PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia.HealthLaurent Degos, Christine Chomienne, Robert West, Dominique Charron, Rose Ann Padua, Jerome Larghero, Marie Robin, Carol le Pogam, Marie-Helene Schlageter, Sacha Muszlak, Jan Fric, Philippe Rousselot, Thi Hai Phan, Liesbeth Mudde, Helene Teisserenc, Antoine F. Carpentier, Scott Kogan, Marika Pla, Michael J. Bishop, Freda Stevenson
Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL.HealthWulf Palinski, Joseph L. Witztum, Christopher J. Binder, Sohvi Horkko, Asheesh Dewan, Mi-Kyung Chang, Emily P. Kieu, Carl S. Goodyear, Peter X. Shaw, Gregg J. Silverman
Points of control in inflammation.(Nature insight reviews)HealthCarl Nathan
Polyglutamine neurodegeneration: minding your Ps and Qs.HealthHenry Paulson
Post-transplant kaposi sarcoma originates from the seeding of donor-derived progenitors.HealthMario Luppi, Patrizia Barozzi, Thomas F. Schulz, Giuseppe Torelli, Fabio Facchetti, Cristina Mecucci, Milena Alu, Ronit Sarid, Valeria Rasini, Luisa Ravazzini, Elisa Rossi, Silvana Festa, Barbara Crescenzi, Dana G. Wolf
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning.HealthYan Li, Yidong Chen, Zhao-You Tang, Zeng-Chen Ma, Richard (French biblical critic) Simon, Qing-Hai Ye, Lun-Xiu Qin, Marshonna Forgues, Ping He, Jin Woo Kim, Amy C. Peng, Ana L. Robles, Zhi-Quan Wu, Sheng-Long Ye, Yin-Kun Liu, Xin Wei Wang
Predicting the future of breast cancer.HealthAke Borg, Carsten Peterson, Marten Ferno
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.HealthDennis R. Burton, Jennifer Jones, Preston A. Marx, John P. Moore, Ronald S. Veazey, Robin J. Shattock, Melissa Pope, J. Christian Kirijan, Qinxue Hu, Tom Ketas, Per Johan Klasse
Prime boost vaccines power up in people.HealthHarriet L. Robinson
Prion disease: bridging the spleen-nerve gap.HealthMoira E. Bruce, Neil A. Mabbott
Probing for prions: recognizing misfolded PrP.(prion protiens)HealthByron Caughey
Progranulin is a mediator of the wound response.HealthZhiheng He, Colin H.P. Ong, Jaroslava Halper, Andrew Bateman
Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells.HealthShuh Narumiya, Kenji Kabashima, Daiji Sakata, Miyako Nagamachi, Yoshiki Miyachi, Inaba, Kayo;
Proteomics delivers on promise of cancer biomarkers.HealthKendall Powell Denver
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.HealthKlaus Pfeffer, Stefan Offermanns, Sorin Tunaru, Jukka Kero, Annette Schaub, Christian Wufka, Andree Blaukat
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.HealthZhu Hong, Ann Marie Schmidt, David Stern, Mark Kindy, Bernd Arnold, Blas Frangione, Jorge Ghiso, Peter Nawroth, Rashid Deane, Lawrence Manness, Deborah Welch, Hogg Elizabeth, Yan, Shi Du; Lin, Chang; Yu, Jin, Ram Kumar Submamaryan, Don L Armstrong, Alan Stern, Barbara. LaRue, Florence Hofman, Birgit Liliensiek, Suzana Jovanovic, Berislav Zlokovic
Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells.HealthJohn E. Dick, Monica Doedens, Frederic Mazurier, Olga I. Gan
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors.HealthDavid J. Mangelsdorf, Peter Tontonoz, Sean B. Joseph, Antonio Castrillo, Bryan A. Laffitte
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.HealthStewart T. Cole, Ann Williams, Alexander S. Pym, Priscille Brodin, Laleh Majlessi, Roland Brosch, Caroline Demangel, Karen E. Griffiths, Gilles Marchal, Claude LeClerc
Regulation of angiogenesis by hypoxia: role of the HIF system.(hypoxia-inducible factor)HealthPeter J. Ratcliffe, Christopher W. Pugh
Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure.HealthDavid P. Siderovski, Yan Zhu, Ping Lu, Michael E. Mendelsohn, Mark Aronovitz, Richard H. Karas, Mary Tang, Guang Wang, Scott P. Heximer, Kevin M. Kaltenbronn, Kendall J. Blumer
Rethinking the central cause of diabetes.HealthJoel K. Elmquist, Jacob N. Marcus
RNA interference targeting Fas protects mice from fulminant hepatitis.HealthJudy Lieberman, Erwei Song, Sang-Kyung Lee, Jie Wang, Nedim Ince, Nengtai Ouyang, Jun Min, Jisheng Chen, Premlata Shankar
Road map to metastasis.(cancer metastasis)HealthLaura J. Van't Veer, Britta Weigelt
Robert Webster.(Prophets)HealthApporva Mandavilli
Role of PLGF in the intra-and intermolecular cross talk between the VEGF receptors Flt1 and Flk1.HealthDidier Communi, Peter Carmeliet, Mieke Dewerchin, Lieve Moons, Maria De Mol, Diether Lambrechts, Stephane Plaisance, Edward M. Conway, Monica Autiero, Jens Kroll, Johannes Waltenberger, Domenico Maglione, Kurt Ballmer, Guido; Hofer, Stefanie; Fellbirch, BonoFrancoise; Kliche, Danica Stanimirovic, Saskia Dombrowski, Ulrike Mayr Beyrle, Andrea Kranz, Jean Mark Herbert, Graziella Persico, Daniel J Hicklin, Christoph Dehio, Paul Van Hummelen, Collen, Desire;, Masabumi Shibuya, David Communi
Rules of conduct for the cystic fibrosis anion channel.HealthJeffrey J. Wine
Salt and wounds: a new mechanism for neuropathic path.HealthKevin Staley
Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities.HealthMasayoshi Shichiri, Shinya Ishimaru, Toshio Ota, Tetsuo Nishikawa, Takoa Isogai
Sealing the leak, healing the heart.(sudden cardiac death)HealthWalter J. Koch, Patrick Most
Seizing hold of seizures.(new therapies for epilepsy)HealthGregory L. Holmes
Sensing heart stress.HealthLiza Barki-Harrington, Howard A. Rockman
Setting the cytokine trap for autoimmunity.HealthCharles A. Dinarello
Shedding light onto live molecular targets.HealthRalph Weissleder, Vasilis Ntziachristos
Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates.HealthMargaret A. Goodell, Fernando D. Camargo, Rahshaana Green, Yassemi Capetenaki, Kathyjo A. Jackson
Skipping to new therapies for muscular dystrophy.HealthJames G. Tidball, Melissa J. Spencer
SOCS-3 regulates onset and maintenance of T sub H 2- mediated allergic responses.(suppressor of cytokine signaling)HealthAnne O'Garra, Akihiko Yoshimura, Yoh-ichi Seki, Hiromasa Inoue, Naoko Nagata, Katsuhiko Hayashi, Satoru Fukuyama, Koichiro Matsumoto, Okiru Komine, Shinjiro Hamano, Kunisuke Himeno, Kyoko Inagaki-Ohara, Cacalano Nicholas, Tadahilo Oshida, Hirohisa Saito, James A Johnston, Masato Kubo
Splitting vessels: keeping lymph apart from blood.HealthShahin Rafii, Mihaela Skobe
Sprawling Biopolis jazzes up Singapore's science scene.HealthMichael Frith
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier.(src-suppressed C-kinase )HealthSae-Won Lee, Woo Jean Kim, Yoon Kyung Choi, Hyun Seok Song, Son, Myung Jin;Gelman, Irwin H.; Kim, Yun
Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system.HealthAnn Marie Schmidt, Xi Chen, Hong Jiang, David M. Stern, Chris Brown, Shirley ShiDu Yan, Zhi-Ying Wu, Hui Ping Zhang, Glaucia Furtado, Shi Fang Yan, alan Stern, Juan LaFaille, Leonard Chess
Tales of a Hobbesian Cynic.(Book Review)HealthJoseph P. Rauschecker
Taming transplantation with T cells.HealthShimon Sakaguchi
Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells.HealthLuigi Naldini, Michele De. Palma, Mary Anna. Venneri, Cristina Roca
Tat's seductive side.HealthMario Stevenson
T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation.HealthLouis J. Muglia, Barry P. Sleckman, Judson A. Brewer, Bernard Khor, Sherri K. Vogt, Lisa M. Muglia, Hideji Fujiwara, Karen E. Haegele
T-cell mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura.HealthBob Olsson, Per-Ola Anderson, Margareta Jernas, Stefan Jacobsson, Bjorn Carlsson, Lena M S. Carlsson
T cells bite the hand that feeds them.HealthJonathan W. Yewdell, David C. Tscharke
Technology, tradition unite in India's drug discovery scheme.HealthK.S. Jayaraman
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes.HealthJean-Francois Bach, Meriam Belghith, J Bluestone, Samia Barriot, Jerome Megret, Lucienne Chatenoud
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif.HealthMichael H. Malim, Ann M. Sheehy, Nathan C. Gaddis
The biology of VEGF and its receptors.(Vascular endothelial growth factor)HealthNapoleone Ferrara, Jennifer LeCouter, Hans-Peter Gerber
The complexities of skeletal biology.HealthGerard Karsenty
The early years of HIV research: integrating clinical and basic research.HealthFrancoise Barre-Sinoussi
The eukaryotic transcriptional machinery: complexities and mechanisms unforseen.HealthRobert G. Roeder
The genetic basis for skeletal diseases.HealthBjorn R. Olsen, Elazar Zelzer
The immunopathogenesis of sepsis.(Nature insight reviews)HealthJonathan Cohen
The inflammatory reflex.(Nature insight reviews)HealthKevin J. Tracey
The nucleolus: at the stem of immortality.HealthPier Paolo Pandolfi, Rosa Bernardi
The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.HealthStephen A. Duncan, Richard B. Kim, Frank J. Gonzalez, Rommel G. Tirona, Wooin Lee, Brenda F. Leake, Lu-Bin Lan, Cynthia Brimer Cline, Vishal Lamba, Fereshteh Parviz, Yusuke Inoue, Erin G. Schuetz
Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A).HealthKlaus-Armin Nave, Ueli Suter, Michael W. Sereda, Gerd Meyer zu Horste, Naureen Uzma
Therapeutic dendritic-cell vaccine for simian AIDS.HealthJean-Marie Andrieu, Wei Lu, Xiaoxian Wu, Yaozeng Lu, Weizhong Guo
Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration.HealthDavid Lyden, Shahin Rafii
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo.HealthRafi Ahmed, Joseph N. Blattman, Jason M. Grayson, E. John Wherry, Susan M. Kaech, Kendall A. Smith
The road to research is paved with restrictions.(patient privacy)HealthAlan Dove, Myrna Watanabe, Laura Bonetta
The sympathetic nervous system is involved in variant Creutzfeldt-Jakob disease.HealthJean-Jacques Hauw, Stephane Haik, Baptiste A. Faucheux, Veronique Sazdovitch, Nicholas Privat, Jean-Louis Kemeny, Armand Perret-Liaudet
The thrombomodulin-protein C system is essential for the maintenance of pregnancy.HealthJay L. Degen, Nigel Mackman, Rafal Pawlinski, Berend Isermann, Rashmi Sood, Mark Zogg, Shawn Kalloway, Hartmut Weiler
The total artificial heart.HealthDenton A. Cooley
The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intesinal ischemia-reperfusion.HealthMichael Karin, Florian R. Greten, Lee-Wei Chen, Laurence Egan, Zhi-Wei Li, Martin F. Kagnoff
The unhealthy Earth.(Book Review)HealthJoseph Grzymski
TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases.HealthRavinder Maini, Mark Feldmann
Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells.HealthHector Molina, Jeong-Hyeon Sohn, Puran S. Bora, Hye-Jung Sur, Henry J. Kaplan, Nalini S. Bora
Toll-like receptor-4 (TLR) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors.HealthJie Fan, Asrar B.Research Malik
Transcription factor Ggr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth.HealthRoger G. Fahmy, Crispin R. Dass, Lun-Quan Sun, Colin N. Chesterman, Levon M. Khachigian
Transmission, acute HIV-1 infection and the quest for strategies to prevent infection.HealthMelissa Pope, Ashley T Haase
Trends in microarray analysis.HealthRobin L. Stears, Todd Martinsky, Mark Schena
Twenty years of therapy for HIV-1 infection.HealthRoger J. Pomerantz, David L. Horn
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma.HealthGustav Mattiasson, Mehrdad Shamloo, Gunilla Gido, Kavitha Mathi, Gregor Tomasevic, Saili Yi, Craig H. Warden, Roger F. Castilho, Thorsten Melcher, Mirella Gonzalez-Zulueta, Karoly Nikolich, Tadeusz Wieloch
Unmet expectations: the brain minds.HealthRoy A. Wise, William A. Jr. Carlezon
Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI.HealthRichard J. Traystman, Zhou Jinyuan, David A. Wilson, Peter C.M. Van Zijl, Jean-Francois Payen
US ponders law on genetic discrimination.HealthErika Check
US to limit AIDS trials in developing nations.HealthTinker Ready
vCJD epidemic could be first of many, experts warn.HealthLaura Spinney
VEGF: A modifier of the del122q11 (DiGeorge) syndrome?.HealthPeter Carmeliet, Mieke Dewerchin, Desire Collen, Veerle Compernolle, Lieve Moons, Peter Scambler, Ingeborg Stalmans, Jian Wang, Diether Lambrechts, Frederik De Smet, Sandra Jansen, Sunit Maity, Paige Kneer, Maren von der Ohe, Ann Swillen, Christa Maes, Marc Gewillig, Daniel G.M. Molin, Peter Hellings, Thurid Boetel, Maartin Haardt, Stephane Plaisance, Robert Vlietinck, Beverly Emanuel, Adriana C. Gittenberger-de Groot, Bernice Morrow, Deborah A. Driscol, Camila V. Esguerra, Geert Carmeliet, Annett Behn-Krappa, Koen Devriendt, Simon J. Conway
Wait of the world falls on Bush's ambitious AIDS plan.HealthTabitha M. Powledge
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