Genes & Development 2001 |
Title | Subject | Authors |
Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain.(Statistical Data Included) | Biological sciences | Jamey D. Marth, Luis F. Parada, Patrick Charnay, Yuan Zhu, Mario I. Romero, Pritam Ghosh, Zhengyi Ye, Elizabeth J. Rushing |
ABP1 is required for organized cell elongation and division in Arabidopsis embryogenesis.(Statistical Data Included) | Biological sciences | Jin-Gui Chen, Hemyet Ullah, Jeffery C. Young, Michael R. Sussman, Alan M. Jones |
A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction.(Statistical Data Included) | Biological sciences | Josef Loidl, Pawel Pasierbek, Michael jantsch, Martin Melcher, alexander Schleiffer, Dieter Schweizer |
A complex containing CstF-64 and the SL2 snRNP connects mRNA 3' end formation and trans-splicing in C. elegans operons.(Caenorhabditis elegans)(Statistical Data Included) | Biological sciences | Donald Evans, Ismael Perez, Margaret MacMorris, Devin Leake, Carol J. Wilusz, Thomas Blumenthal |
A conserved MYB transcription factor involved in phosphate starvation signaling both in vascular plants and in unicellular algae.(Statistical Data Included) | Biological sciences | Vicente Rubio, Francisco Linhares, Roberto Solano, Ana C. Martin, Joaquin Iglesias, Antonio Leyva, Javier Paz-Ares |
A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Mat(alpha)2 repressor degradation.(Statistical Data Included) | Biological sciences | Mark Hochstrasser, Robert Swanson, Martin Locher |
A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene.(Statistical Data Included) | Biological sciences | Frederic Rosa, Thomas Dickmeis, Philippe Mourrain, Alure Saint-Etienne, Nadine Fischer, Pia Aanstad, Matthew Clark, Uwe Strahle |
Activation of the Notch-regulated transcription factor CBF1/RBP-Jk through the 13SE1A oncoprotein. | Biological sciences | Achim Leutz, Stephane Ansieau, Lothar J. Strobl |
Activator-mediated disruption of sequence-specific DNA contacts by the general transcription factor TFIIB.(Statistical Data Included) | Biological sciences | Stefan G.E. Roberts, Rachel Evans, Jennifer Fairley |
Active repression and E2F inhibition by pRB are biochemically distinguishable. | Biological sciences | Richard Gregory, Brian David Dynlacht, John F. Ross, Anders Naar, Hieu Cam |
Active repression of RAR signaling is required for head formation.(Retinoic acid receptors)(Statistical Data Included) | Biological sciences | Michael Downes, Bruce Blumberg, Tetsuya Koide, Roshantha A.S. Chandraratna, Kazuhiko Umesono |
A developmental transition in definitive erythropoiesis: erythropoietin expression is sequentially regulated by retinoic acid receptors and HNF4.(Statistical Data Included) | Biological sciences | Hong Wu, Makina, Hernandez-Hoyos, Tim Hun-Po Chen, Ellen V. Rothenberg, Henry M. Sucov |
A DNA replication-arrest site RTS1 regulated imprinting by determining the direction of replication at mat1 in S. pombe.(Schizosaccharomyces pombe)(Statistical Data Included) | Biological sciences | Jacob Z. Dalgaard, Amar J.S. Klar |
A homeobox gene, PRESSED FLOWER, regulates lateral axis-dependent development of Arabidopsis flowers.(Statistical Data Included) | Biological sciences | Noritaka Matsumoto, Kiyotaka Okada |
A homeotic mutation in the trithorax SET domain impedes histone binding.(Statistical Data Included) | Biological sciences | |
A model for the abrogation of the SOS response by an SOS protein: a negatively charged helix in DinI mimics DNA in its interaction with RecA. | Biological sciences | Oleg N. Voloshin, Benjamin E. Ramirez, Ad Bax, R. Daniel Camerini-Otero |
Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in Drosophila.(Statistical Data Included) | Biological sciences | Harvey T. McMahon, Cahir J. O'Kane, Azam Razzaq, Iain M. Robinson, Jeremy N. Skepper, Ya Su, Andrew C. Zelhof, Anthoy P. Jackson, Nicholas J. Gay |
A multistep damage recognition mechanism for global genomic nucleotide excision repair.(Statistical Data Included) | Biological sciences | Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai, Kaoru Sugasawa, Tomoko Okamoto, Yuichiro Schimizu |
A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease. | Biological sciences | Martin Wagner, Florian R. Greten, Christoph K. Weber, Stefan Koschnick, Torsten Mattfeldt, Wolfgang Deppert, Horst Kern, Guido Adler, Roland M. Schmid |
A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hemotological and skeletal phenotype of flexed-tail (f/f) mice.(Statistical Data Included) | Biological sciences | Mark D. Fleming, Nancy C. Andrews, Dean R. Campagna, Judith N. Haslett, Cameron C. Trenor III |
A mutation in the Gsk3-binding domain of zebrafish masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon.(Statistical Data Included) | Biological sciences | Gerd-Jorg Rauch, Robert Geisler, Carl-Philipp Heisenberg, Corinne Houart, Masaya Take-uchi, Neville Young, Pedro Coutinho, Ichiro Masai, Luca Caneparo, Miguel L. Concha, Trevor C. Dale, Stephen W. Wilson, Derek L. Stemple |
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.(Statistical Data Included) | Biological sciences | Tyler Jacks, Roderick T. Bronson, Kim Mercer, Denise Crowley, David A. Tuveson, ERica L. Jackson, Nicholas Willis, Yarmond Montoya |
Analysis of the transcriptional program induced by Raf in epithelial cells.(Statistical Data Included) | Biological sciences | Martin McMahon, Almut Schulze, Julian Downward, Derstin Lehmann, Harold B.J. Jefferies |
A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases.(small ubiquitin-related modifier)(protein inhibitor of activated signal transducers and activators of transcription)(Statistical Data Included) | Biological sciences | Peter K. Jackson |
A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts.(Statistical Data Included) | Biological sciences | Joan A. Steitz, Gia K. Voeltz, Julina Ongkasuwan, Nancy Standart |
A novel labeling technique reveals a function for histone H2A/H2B dimer tail domains in chromatin assembly in vivo.(Statistical Data Included) | Biological sciences | Christophe Thiriet, Jeffrey J. Hayes |
An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway.(Statistical Data Included) | Biological sciences | Tony Hunter, John Moniakis, Satoru Funamoto, Masashi Fukuzawa, Jill Meisenhelder, Tsuyoshi Araki, Tomoaki Abe, Ruedi Meili, Jeffrey Williams, Richard A. Firtel |
Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism.(Statistical Data Included) | Biological sciences | Shun Yamaguchi, Hitoshi Okamura, Shigeru Mitsui, Yoshiki Ishida, Takuya Matsuo |
A plastidic ABC protein involved in intercompartmental communication of light signaling.(Statistical Data Included) | Biological sciences | Nam-Hai Chua, Simon Geir Moller, Tim Kunkel |
Arabidopsis cmt3 chromomethylase mutations block non-CG methylation and silencing of an endogenous gene.(Statistical Data Included) | Biological sciences | Judith Bender, Lisa Bartee, Fabienne Malagnac |
Asf1 links Rad53 to control of chromatin assembly.(Statistical Data Included) | Biological sciences | Stephen J. Elledge, Fenghua Hu, Annette A. Alcasabas |
Ataxia telangiectasia mutated is essential during adult neurogenesis.(Statistical Data Included) | Biological sciences | Fred H. Gage, Duane M. Allen, Henriette Van Praag, Jasodhara Ray, Zoe Weaver, Christopher J. Winrow, Todd A. Carter, Ray Braquet, Elizabeth Harrington, Thomas Ried, Kevin D. Brown, Carrolee Barlow |
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.(Statistical Data Included) | Biological sciences | Seong-Tae Kim, Michael B. Kastan, Yosef Shiloh, Ze'ev Ronai, Ohad Shifman, Moshe Oren, Ruth Maya, Moshe Balass, Dganit Shkedy, Juan-Fernando Martinez Leal, Miri Moas, ThomaS Buschmann, Ephraim Katzir |
A zebrafish nanos-related gene is essential for the development of primordial germ cells. | Biological sciences | Bernard Thisse, Christine Thisse, Marion Koprunner, Erez Raz |
Bacillus subtilis CodY represses early-stationary-phase genes by sensing GTP levels.(Statistical Data Included) | Biological sciences | Manoja Ratnayake-Lecamwasam, Pascale Serror, Ka-Wing Wong, Abraham L. Sonenshein |
Beyond the Qs in the polyglutamine diseases.(Statistical Data Included) | Biological sciences | |
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak.(Statistical Data Included) | Biological sciences | Tullia Lindsten, Craig B. Thompson, Wei-Xing Zong, Andrea J. Ross, Grant R. MacGregor |
Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes.(Statistical Data Included) | Biological sciences | Anton Wutz, Ronald Zwart, Frank Sleutels, Alfred H. Schinkel, Denise P. Barlow |
BIG: a calossin-like protein required for polar auxin transport in Arabidopsis.(Statistical Data Included) | Biological sciences | Joanne Chory, Mark Estelle, Pedro Gil, Elizabeth Dewey, Jiri Friml, Yunde Zhao, Kimberley C. Snowden, Jo Putterill, Klaus Palme |
Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.(Statistical Data Included) | Biological sciences | Scott R. Frank, Marianne Schroeder, Paula Fernandez, Stefan Taubert, Bruno Amati |
Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action.(Statistical Data Included) | Biological sciences | Martin Buck, Paul Casaz, Matthew Chaney, Ricardo Grande, Siva R. Wigneshweraraj, Wendy Cannon, Mari-Trinidad Gallegos, Jorg Schumacher, Susan Jones, Sarah Elderkin, Angel Ernesto Dago, Enrique Morett |
biniou (FoxF), a central component in a regulatory network controlling visceral mesoderm development and midgut morphogenesis in Drosophila. | Biological sciences | Manfred Frasch, Hsiu-Hsiang Lee, stephane Zaffran, Axel Kuchler |
BMPs on the road to hepatogenesis.(Bone morphogenic proteins)(Statistical Data Included) | Biological sciences | Stephen A. Duncan, Alistair J. Watt |
Bridging cytoskeletal intersections.(Statistical Data Included) | Biological sciences | Elaine Fuchs, Iakowos Karakesisoglou |
Brinker is a sequence-specific transcriptional repressor in the Drosophila embryo. | Biological sciences | Hailan Zhang, Michael Levine, Hilary L. Ashe |
Building better vasculature.(Statistical Data Included) | Biological sciences | |
c(3)G encodes a Drosophila synaptonemal complex protein.(crossover suppressor on 3 of Gowen)(Statistical Data Included) | Biological sciences | R. Scott Hawley, Scott L. Page |
Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD.(Statistical Data Included) | Biological sciences | Nova Fong, David L. Bentley |
casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafish.(Statistical Data Included) | Biological sciences | Bernard Thisse, Christine Thisse, Yutaka Kikuchi, Jonathan Alexander, Deborah Yelon, Didier Y.R. Stainier, Steven Waldron, Antoine Agathon |
Cdc13 both positively and negatively regulates telomere replication. | Biological sciences | Abha Chandra, Timothy R. Hughes, Constance I. Nugent, Victoria Lundbald |
C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(sub/2) DNA damage checkpoint.(Caenorhabditis elegans)(Statistical Data Included) | Biological sciences | Anne M. Villeneuve, Gregory M. Chin |
Cell cycle checkpoint signaling through the ATM and ATR kinases.(ataxia-telangiectasia mutated, ATM Rad 3-related)(Statistical Data Included) | Biological sciences | Robert T. Abraham |
Changing colors in mice: an inducible system that delivers.(Statistical Data Included) | Biological sciences | Alea A. Mills |
Characterization of U4 and U6 interactions with the 5' splice site using a S. cerevisiae in vitro trans-splicing system.(Saccharomyces)(Statistical Data Included) | Biological sciences | Tracy L. Johnson, John Abelson |
Chloroplast DNA methylation and inheritance in Chlamydomonas.(Statistical Data Included) | Biological sciences | James G. Umen, Ursula W. Goodenough |
Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro.(Statistical Data Included) | Biological sciences | Antonin V. Tutter, Christy J. Fryer, Katherine A. Jones |
Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.(Statistical Data Included) | Biological sciences | Adrian Bird, Brian Hendrich, Jacquieline Guy, Bernard Ramsahoye, Valerie A. Wilson |
COBRA encodes a putative GPI-anchored protein, which is polarly localized and necessary for oriented cell expansion in Arabidopsis.(Statistical Data Included) | Biological sciences | Jee Jung, Philip N. Benfey, Gary Schindelman, Atsushi Morikami, Tobias I. Baskin, Nicholas C. Carpita, Paul Derbyshire, MAureen C. McCann |
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein.(Statistical Data Included) | Biological sciences | A. Gregory Matera, Michael D. Hebert, Piotr W. Szymczyk, Karl B. Shpargel |
Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. | Biological sciences | Patricia Ducy, Shu Takeda, Gerard Karsenty, Jean-Pierre Bonnamy, Michael J. Owen |
Control of axillary bud initiation and shoot architecture in Arabidopsis through the SUPERSHOOT gene.(Statistical Data Included) | Biological sciences | Titima Tantikanjana, Jean W.H. Yong, D. Stuart Letham, Megan Griffith, Mumtaz Hussain, Karin Liung, Goran Sandberg, Venkatesan Sundaresan |
Control of cell division by a retinoblastoma protein homolog in Chlamydomonas.(Statistical Data Included) | Biological sciences | James G. Umen, Ursula W. Goodenough |
Conversion of a gene-specific repressor to a regional silencer.(Statistical Data Included) | Biological sciences | Laura N. Rusche, Jasper Rine |
Cooperation between C/EBP(alpha) TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation.(Statistical Data Included) | Biological sciences | Achim Leutz, Claus Nerlov, Thomas Askov Pedersen, Elisabeth Kowenz-Leutz |
Core promoters: active contributors to combinatorial gene regulation.(Statistical Data Included) | Biological sciences | Stephen T. Smale |
COUP-TFI: an intrinsic factor for early rationalization of the neocortex.(Statistical Data Included) | Biological sciences | Ming-Jer Tsai, Cheng Zhou, Sophia Y. Tsai |
CREating a SCAP-less liver keeps SREBPs pinned in the ER membrane and prevents increased lipid synthesis in response to low cholesterol and high insulin.(sterol regulatory element binding proteins, endoplasmic reticulum,)(Statistical Data Included) | Biological sciences | Timothy F. Osborne |
Critical roles of PPAR(beta)/(delta) in keratinocyte response to inflammation.(Statistical Data Included) | Biological sciences | Walter Wahli, Nguan Soon Tan, Liliane Michalik, Noa Noy, Rubina Yasmin, Corinne Pacot, Manuel Heim, Beat Fluhmann, Beatrice Desvergne |
Curbing the nonsense: the activation and regulation of mRNA surveillance.(Review) | Biological sciences | Stuart W. Peltz, Carol J. Wilusz, Weirong Wang |
D box and KEN box motifs in budding yeast Hswl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p.(Destruction box, anaphase-promoting complex)(Statistical Data Included) | Biological sciences | Janet L. Burton, Mark J. Solomon |
Deconstructing Myc.(Statistical Data Included) | Biological sciences | Robert N. Eisenman |
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex.(Statistical Data Included) | Biological sciences | William G. Kaelin, Emmanuelle Querido, Joan Weliky Conaway, Ronald C. Conaway, Paola Blanchette, Qin Yan, Takumi Kamura, Megan Morrison, Dominique Boivin, Philip E. Branton |
Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase.(Statistical Data Included) | Biological sciences | Amy L. Kistler, Christine Guthrie |
Delta signaling from the germ line controls the proliferation and differentiation of the somatic follicle cells during Drosophila oogenesis. | Biological sciences | Hernan Lopez-Schier, Daniel St. Johnston |
Dendrites.(Statistical Data Included) | Biological sciences | Yuh-Nung Jan, Lily Yeh Jan |
Developmental regulation of transcription by a tissue-specific TAF homolog.(Statistical Data Included) | Biological sciences | Margaret T. Fuller, Mark A. Hiller, Ting-Yi Lin, Cricket Wood |
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans.(Caenorhabditis)(Statistical Data Included) | Biological sciences | Gregory J. Hannon, Emily Bernstein, Rene F. Ketting, Titia Sijen, Ronald H. A. Plasterk, Sylvia E. J. Fischer |
Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR(beta).(Statistical Data Included) | Biological sciences | Janet Rossant, Gilles b. Tremblay, Tilo Kunath, Denis Bergeron, Line Lapointe, Celine Champigny, Jo-Ann Bader, Vincent Giguere |
Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis.(Statistical Data Included) | Biological sciences | Esther De Graaff, Shankar Srinivas, Carol Kilkenny, Vivette D'Agati, Baljinder S. Mankoo, Frank Costantini, Vassilis Pachnis |
Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm.(Statistical Data Included) | Biological sciences | Jennifer Rossi, N. Ray Dunn, Brigid L.M. Hogan, Kenneth S. Zaret |
Division site selection protein DivIVA of Bacillus subtilis has a second distinct function in chromosome segregation during sporulation.(Statistical Data Included) | Biological sciences | Helena B. Thomaides, Marcelle Freeman, Meriem El Karoui, Jeffrey Errington |
Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas.(Statistical Data Included) | Biological sciences | Jerold E. Rehg, Charles J. Sherr, David H. Randle, Kazushi Inour, Frederique Zindy |
Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells.(Statistical Data Included) | Biological sciences | Fumio Hanaoka, Patricia Kannouche, Bernard C. Broughton, Marcel Volker, Leon H.F. Mullenders, Alan R. Lehmann |
Down-regulation of TDT transcription in DC4(super.+)CD8(super.+) thymocytes by Ikaros proteins in direct competition with an Ets activator.(Statistical Data Included) | Biological sciences | Le A. Trinh, Bradley S. Cobb, Stephen T. Smale, Roger Ferrini, Amy S. Weinmann, Kyungmin Hahm, Patricia Ernst, Isla P. Garraway, Matthias Merkenshlager |
Drosophila Brain Tumor is a translational repressor.(Statistical Data Included) | Biological sciences | Junichiro Sonoda, Robin P. Wharton |
Drosophila Fos mediates ERK and JNK signals via distinct phosphorylation sites.(Statistical Data Included) | Biological sciences | Laura Ciapponi, David B. Jackson, Marek Mlodzik, Dirk Bohmann |
Drosophila Separase is required for sister chromatid separation and binds to PIM and THR.(Statistical Data Included) | Biological sciences | Alf Herzig, Stefan Heidmann, Christian F. Lehner, Hubert Jager |
Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression.(Statistical Data Included) | Biological sciences | Eileen Sullivan, Carlos Santiago, Emily D. Parker, Zbigniew Dominski, Xiaocui Yang, David J. Lanzotti, Tom C. Ingledue, William F. Marzluff, Robert J. Duronio |
Dynamic expression and essential functions of Hes7 in somite segmentation.(Statistical Data Included) | Biological sciences | Shuichi Yamada, Yasumasa Bessho, Ryoichi Sakata, Suguru Komatsu, Kohei Shiota, Ryoichiro Kageyama |
E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos. | Biological sciences | Jacqueline A. Lees, Ulrike Ziebold, Tammi Reza, Alicia Caron |
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.(Statistical Data Included) | Biological sciences | Kristian Helin, Heiko Muller, Adrian P. Bracken, Richard Vernell, M. Cristina Moroni, Fred Christians, Emanuela Grassilli, Elena Prosperini, Elena Vigo, Jonathan D. Olimer |
Ectopic expression of a Chlamydomonas mt+-specific homeodomain protein in mt-gametes initiates zygote development without gamete fusion.(Statistical Data Included) | Biological sciences | Hui Zhao, Min Lu, Ritu Singh, William J. Snell |
EID1, an F-box protein involved in phytochrome A-specific light signaling.(Statistical Data Included) | Biological sciences | Dieterli, Yong-Chun Zhou, Eberhard Schafer, Markus Funk, Thomas Kretsch |
Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins.(Statistical Data Included) | Biological sciences | Julie D.R. Reimann, Peter K. Jackson, Bryan E. Gardner, Florence Margottin-Goguet |
Enhancer-promoter specificity mediated by DPE or TATA core promoter motifs.(Statistical Data Included) | Biological sciences | James T. Kadonaga, Jennifer E.F. Butler |
Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control.(Statistical Data Included) | Biological sciences | Susan D. Croll, George D. Yancopoulos, Nicholas W. Gale, Klas Kullander, Manuel Zimmer, Li Pan, Joyce McClain, Virginia Hughes, Stephanie Zabski, Thomas M. DeChiara, Rudiger Klein |
Establishment of Polycomb silencing requires a transient interaction between PC and ESC.(Statistical Data Included) | Biological sciences | Sylvain Poux, Raffaella Melfi, Vincenzo Pirrotta |
FHY1: a phytochrome A-specific signal transducer.(Statistical Data Included) | Biological sciences | Thierry Desnos, Pilar Puente, Garry C. Whitelam, Nicholas P. Harberd |
FIERY1 encoding an inositol polyphosphate 1-phosphatase is a negative regulator of abscisic acid and stress signaling in Arabidopsis.(Statistical Data Included) | Biological sciences | Hojoung Lee, Liming Xiong, Manabu Ishitani, Jian-Kang Zhu, Byeong-ha Lee, Changqing Zhang |
FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity.(factor inhibiting hypoxia-inducible factor 1)(hypoxia-inducible factor 1)(von Hippel-Lindau tumor suppressor protein)(Statistical Data Included) | Biological sciences | Gregg L. Semenza, Patrick C. Mahon, Kiichi Hirota |
Fine structure of E. coli RNA polymerase-promoter interactions: alpha subunit binding to the UP element minor groove. | Biological sciences | Wilma Ross, Alexander Ernst, Richard L. Gourse |
Formation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3.(Statistical Data Included) | Biological sciences | Qiufu Ma, Senji Shirasawa, Ying Qian, Bernd Fritzsch, Chih-Li Chen, Yoojin Choi |
FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse.(Statistical Data Included) | Biological sciences | Jeffrey L. Wrana, Janet Rossant, Pamela A. Hoodless, Melanie Pye, Claire Chazaud, Etienne Labbe, Liliana Attisano |
Functional antagonism between E2F family members.(Statistical Data Included) | Biological sciences | Maxim V. Frolov, David S. Huen, Olivier Stevaux, Dessislava Dimova, Kristi Balczarek-Strang, Mark Elsdon, Nicholas J. Dyson |
Functional comparison of the nematode Hox gene lin-39 in C. elegans and P. pacificus reveals evolutionary conservation of protein function despite divergence of primary sequences.(Statistical Data Included) | Biological sciences | Kaj Grandien, Ralf J. Sommer |
Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes.(Statistical Data Included) | Biological sciences | Jason K. Kim, Ana M. Fernandez, Shoshana Yakar, Joelle Dupont, Catalina Hernandez-Sanchez, Arthur L. Castle, Jonathan Filmore, Gerland I. Shulman, Derek Le Roith |
Functionally distinct, sequence-specific replicator and origin elements are required for Drosophila chorion gene amplification.(Statistical Data Included) | Biological sciences | Lucy Lu, Hongjun Zhang, John Tower |
Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease.(Statistical Data Included) | Biological sciences | Vivek Kaliraman, Janet R. Mullen, Fricke M. William, Suzanne A. Bastin-Shanower, Steven J. Brill |
Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival.(Statistical Data Included) | Biological sciences | Pamela L. Schwartzberg, Harold E. Varmus, Lianpng Xing, Ana M. Venegas, Amy Chen, Lisa Garrett-Beal, Brendan Boyce |
Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays.(Statistical Data Included) | Biological sciences | Stanley N. Cohen, Jianqiang Huang, Chih-Jian Lih, Kuang-Hung Pan |
Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene.(Statistical Data Included) | Biological sciences | Kathrin Gottlob, Nissim Hay, William S. Chen, Pei-Zhang Xu, Mei-Ling Chen, Karen Sokol, Tanya Shiyanova, Igor Roninson, Wei Weng, Ryo Suzuki, Kazuyuki Tobe, Takashi Kadowaki |
Haplo-insufficiency? Let me count the ways.(Statistical Data Included) | Biological sciences | Anton Berns, Kim C. Quon |
Hedgehog signaling in animal development: paradigms and principles.(Statistical Data Included) | Biological sciences | Andrew P. McMahon, Philip W. Ingham |
Hierarchical phosphorylation of the translation inhibitor 4E-BP1. | Biological sciences | Stephen K. Burley, Ruedi Aebersold, Nahum Sonenberg, Anne-Claude Gingras, Brian Raught, Steven P. Gygi, Anna Niedzwiecka, Mathieu Miron, Roberto D. Polakiewicz, Aleksandra Wyslouch-Cieszynska |
Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae.(Statistical Data Included) | Biological sciences | Brian D. Strahl, Fred Winston, Scott D. Briggs, Mary Bryk, Wang L. Cheung, Judith K. Davie, Sharon Y.R. Dent, C.David Allis |
Histone H3 specific acetyltransferases are essential for cell cycle progression.(Statistical Data Included) | Biological sciences | Sam John, LeAnn Howe, Jerry L. Workman, Darryl Auston, Patrick Grant, Richard G. Cook, Lorraine Pillus |
hMSH3 and hMSG6 interact with PCNA and colocalize with it to replication foci.(Statistical Data Included) | Biological sciences | Giancarlo Marra, Josef Jiricny, Hanna E. Kleczkowska, Teresa Lettieri |
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.(Statistical Data Included) | Biological sciences | Robert A. Weinberg, Mark D. Fleming, Brian Elenbaas, Lisa Spirio, Frederick Koerner, Drazen B. Zimonjic, Joana Liu Donaher, Nicholas C. Popescu, William C. Hahn |
Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.(Statistical Data Included) | Biological sciences | Yoichi Taya, Akio Yamashita, Tetsuo Ohnishi, Isao Kashima, Shigeo Ohno |
Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth and survival. | Biological sciences | Heather E. Ryan, Randall S. Johnson, Ernestina Schipani, Susanna Didrickson, Tatsuya Kobayashi, Melissa Knight |
Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56. | Biological sciences | Michael R. Green, Meng Zhang |
Identification and purification of two distinct complexes containing the five RAD51 paralogs.(Statistical Data Included) | Biological sciences | Jean-Yves Masson, Madalena C. Tarsounas, Stasiak. Andrzej, Alicia Z. Stasiak, Raivee Shah, Michael J. Mellwraith, Fikona E. Benson, Stephen C.. West |
Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development.(Caenorhabditis elegans)(Statistical Data Included) | Biological sciences | Min-Ho Lee, Tim Schedl |
Identification of novel small RNAs using comparative genomics and microarrays. | Biological sciences | Susan Gottesman, Karen M. Wassarman, Francis Repoila, Carsten Rosenow, Gisela Storz |
Inactivation of AtRac1 by abscisic acid is essential for stomatal closure.(Statistical Data Included) | Biological sciences | Emmanuel Lemichez, Yan Wu, Juan-Pablo Sanchez, Amel Mettouchi, Jaideep Mathur, Na-Hai Chua |
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes.(Statistical Data Included) | Biological sciences | Harold E. Varmus, Jeffrey A. Whitsett, Galen H. Fisher, Shari L. Wellen, David Klimatra, Joi M. Lenczowski, Jay W. Tichelaat, Martin J. Lizak, Alan Koretsky |
Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha.(Statistical Data Included) | Biological sciences | Randall S. Johnson, Gavin Thurston, Donald M. McDonald, David A. Elson, L. Eric Huang, David G. Ginzinger, Jeffrey M. Arbeit |
Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulation Cdh1.(Statistical Data Included) | Biological sciences | Cathie M. Pfleger, Adrian Salic, Ethan Lee, Marc W. Kirchner |
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. | Biological sciences | Kathrin Gottlob, Nathan Majewski, Scott Kennedy, Eugene Kandel, R. Brooks Robey, Nissim Hay |
Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans.(Statistical Data Included) | Biological sciences | Ji Wu, Anne Duggan, Martin Chalfie |
Inhibition of Wnt activity induces heart formation from posterior mesoderm.(Statistical Data Included) | Biological sciences | Andrew B. Lassar, Martha J. Marvin, Giuliana Di Rocco, Aaron Gardiner, Sara M. Bush |
Intercellular signals regulating pancreas development and function. | Biological sciences | Seung K. Kim, Matthias Hebrok |
Internal ribosome entry sites in eukaryotic mRNA molecules. | Biological sciences | Peter Sarnow, Christopher U.T. Hellen |
In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p.(Statistical Data Included) | Biological sciences | Nicholas A. Kent, Nickoletta Karabetsou, Panagiotis K. Politis, Jane Mellor |
In vivo mechanisms by which tumors producing thrombospondin 1 bypass its inhibitory effects.(Statistical Data Included) | Biological sciences | Noel Bouck, Olga V. Volpert, Stephanie Filleur, Armelle Degeorges, Carole Voland, Frank Reiher, Philippe Clezardin, Florence Cabon |
"It Takes Two to Tango": understanding how centrosome duplication is regulated through the cell cycle.(Statistical Data Included) | Biological sciences | Edward H. Hinchcliffe, Greenfeild Sluder |
Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes. | Biological sciences | Douglas A. Melton, Anne Grapin-Bottom, Amit R Majithia |
KNOX homeodomain protein directly suppresses the expression of a gibberellin biosynthetic gene in the tobacco shoot apical meristem.(Statistical Data Included) | Biological sciences | Tomoaki Sakamoto, Noriko Kamiya, Miyako Ueguchi-Tanaka, Shuichi Iwahori, Makoto Matsuoka |
KOJAK encodes a cellulose synthase-like protein required for root hair cell morphogenesis in Arabidopsis.(Statistical Data Included) | Biological sciences | Peter Shaw, Bruno Favery, Eoin Ryan, Julia Foreman, Paul Linstead, Kurt Boudonck, Martin Steer, Liam Dolan |
Krox-20 patterns the hindbrain through both cell-autonomous and non cell-autonomous mechanisms.(Statistical Data Included) | Biological sciences | Francois Giudicelli, Emmanuel Taillebourg, Patrick Charnay, Pascale Gilardi-Hebenstreit |
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells.(Statistical Data Included) | Biological sciences | Maria Jasin, Andrew J. Pierce, Peng Hu, Mingguang Han, Nathan Elllis |
LAF1, a MYB transcription activator for phytochrome A signaling.(Statistical Data Included) | Biological sciences | Jean-Philippe Vielle-Calzada, Ueli Grossniklaus, Cordelia Bolle, Nam-Hai Chua, Maria L. Ballestreros, M. Lois Luisa, James M. Moore |
Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovation.(Statistical Data Included) | Biological sciences | Jozsef Zakany, Thomas F. Vogt, Francois Spitz, Federico Gonzalez, Catherine Peichel, Denis Deboule |
Lashings of DNA methylation, forkfuls of chromatin remodeling.(Statistical Data Included) | Biological sciences | Irina Stancheva, Richard R. Mehan, Sari Pennings |
Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2.(Statistical Data Included) | Biological sciences | Sagar Sengupta, Bohdan Waslylyk |
Linking nutritional status to gene activation and development.(Statistical Data Included) | Biological sciences | Richard Losick, Jonathan Dworkin |
LIS1 and dynein motor function in neuronal migration and development.(Statistical Data Included) | Biological sciences | Anthony Wynshaw-Boris, Michael J. Gambello |
Localization of the auxin permease AUX1 suggests two functionally distinct hormone transport pathways operate in the Arabidopsis root apex.(Statistical Data Included) | Biological sciences | Malcolm Bennett, Goran Sandberg, Jiri Friml, Klaus Palme, Ranjan Swarup, Alan Marchant, Karin Ljung |
Loss of Werner syndrome protein function promotes aberrant mitotic recombination.(Statistical Data Included) | Biological sciences | Polly R. Prince, Mary J. Emond, RAymond J. Monnat Jr. |
Lsh, a member of the SNF2 family, is required for genome-wide methylation.(Statistical Data Included) | Biological sciences | Kathleen Dennis, Tao Fan, Theresa Geiman, Qingsheng Yan, Kathrin Muegge |
MAD2B is an inhibitor of the anaphase-promoting complex.(Statistical Data Included) | Biological sciences | James Chen, Guowei Fang |
Malignant glioma: genetics and biology of a grave matter. | Biological sciences | David N. Louis, Ronald A. DePinho, Elizabeth A. Maher, Frank B. Furnari, Robert M. Bachoo, David H. Rowitch, Webster K. Cavenee |
Mechanisms controlling differential promoter-occupancy by the yeast forkhead proteins Fkh1p and Fkh2p: implications for regulating the cell cycle and differentiation.(Statistical Data Included) | Biological sciences | Catherine A. Fox, Peter C. Hollenhorst, Gregory Pietz |
Mediator function of the human Rad52B-Rad51C complex in RAd51/RPA-catalyzed DNA strand exchange.(Statistical Data Included) | Biological sciences | Patrick Sung, Stefan Sigurdsson, Stephen Van Komen, Wendy Bussen, David Schild, Joanna S. Albala |
Messenger RNAs are recruited for nuclear export during transcription.(Statistical Data Included) | Biological sciences | Elissa P. Lei, Heike Krebber, Pamela A. Silver |
Mitochondrial Mg (super.2+) homeostasis is critical for group II intron splicing in vivo.(Statistical Data Included) | Biological sciences | Juraj Gregan, Martin Kolisk, Rudolf J. Schwehen |
Mitogen-activated protein kinase phosphatase is required for genotoxic stress relief in Arabidopsis.(Statistical Data Included) | Biological sciences | Jerzy Paszkowski, Roman Ulm, Ekaterina Revenkova, Gian-Pietro di Sansebastiano, Nicole Bechtold |
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines. | Biological sciences | Roger J. Davis, Chen Dong, Cathy Tournier, Richard A. Flavell, Tod K. Turner, Stephen N. Jones |
mRNA 5'-leader trans-splicing in the chordates. | Biological sciences | Amanda E. Vandenberghe, Thomas H. Meedel, Kenneth E.M. Hastings |
Multiple roles for the yeast SUB2/yUAP56 gene in splicing. | Biological sciences | Domenico Libri, Natacha Graziani, Cyril Saguez, J. Boulay |
Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses.(Transforming growth factor activated kinase 1)(Statistical Data Included) | Biological sciences | Sheila Vidal, Ranjiv S. Khush, Francois Leulier, Phoebe Tzou, Makoto Nakamura, Bruno Lemaitre |
Mzf1 controls cell proliferation and tumorigenesis. | Biological sciences | Hal E. Broxmeyer, Pier Paolo Pandolfi, Robert Hromas, Mirella Gaboli, Paraskevi A. Kotsi, Carmela Gurrieri, Giorgio Cattoretti, Simona Ronchetti, Carlos Cordon-Cardo |
naked cuticle targets dishevelled to antagonize Wnt signal transduction.(Statistical Data Included) | Biological sciences | Matthew P. Scott, Keith A. Wharton Jr., Judith A. Mack, Raphael Rouseet, Jeffrey D. Axelrod, Ken M. Cadigan, Matthew P. Fish, Roel Nusse |
Negative regulation of Gen4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase.(Statistical Data Included) | Biological sciences | Raymond J. Deshaies, Richard A. Young, Yong Chi, Michael J. Huddleston, Xiaolong Zhang, Roland S. Annan, Steven A. Carr |
NF-kappaB signaling pathways in mammalian and insect innate immunity.(Statistical Data Included) | Biological sciences | Tom Maniatis, Neal Silverman |
NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the Ligase IV pathway.(Statistical Data Included) | Biological sciences | Marie Frank-Vaillant, Stephane Marcand |
Nitric oxide synthase is induced in sporulation of Physarum polycephalum.(Statistical Data Included) | Biological sciences | Georg Golderer, Ernst R. Werner, Stefan Leitner, Peter Grobner, Gabriele Werner-Felmayer |
Nongenic, bidirectional transcription precedes and may promote developmental DNA deletion in Tetrahymena thermophila.(Statistical Data Included) | Biological sciences | Douglas L. Chalker, Meng-Chao Yao |
Nrarp is a novel intracellular component of the Notch signaling pathway.(Statistical Data Included) | Biological sciences | Chris Kintner, Elise Lamar, Gisele Deblandre, Daniel Wettstein, Volker Gawantka, Nicolas Pollet, Christof Niehrs |
Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2.(Caenorhabditis elegans)(Statistical Data Included) | Biological sciences | Anne M. Villeneuve, Amy J. MacQueen |
Nuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducer.(Statistical Data Included) | Biological sciences | Julie Pilotte, Daniel Larocque, Stephane Richard |
Octamerization of a lambda CI repressor is needed for effective repression of P(sub.RM) and efficient switching from lysogeny.(Statistical Data Included) | Biological sciences | Ian B. Dodd, Alison J. Perkins, Daniel Tsemitsidis, J. Barry Egan |
Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain.(Statistical Data Included) | Biological sciences | Stephen Buratowski, Eun-Jung Cho, Jack Greenblatt, Michael S. Kobor, Minkyu Kim |
Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1. | Biological sciences | Derek J. Richard, Valerie Schumacher, Brigitte Royer-Pokora, Stefan G.E. Roberts |
Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development.(Statistical Data Included) | Biological sciences | Yosuke Kamachi, Masanori Uchikawa, Aki Tanouchi, Ryohei Sekido, Hisato Kondoh |
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo.(Statistical Data Included) | Biological sciences | David N. Louis, Chengkai Dai, Joseph C. Celestino, Yoshifumi Okada, Greory N. Fuller, Eric C. Holland |
Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function. | Biological sciences | Stephen J. Elledge, Jun Qin, Hong Wang, Dou Liu, Yanchang Wang |
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.(small ubiquitin-like modifier)(lymphoid enhancer factor 1)(Statistical Data Included) | Biological sciences | Shrikesh Sachdev, Laurakay Bruhn, Heidemarie Sieber, Andrea Pichler, Frauke Melchior, Rudolf Grosschedl |
PIE-1 is a bifunctional protein that regulates maternal and zygotic gene expression in the embryonic germ line of Caenorhabditis elegans.(Statistical Data Included) | Biological sciences | Christina Tenenhaus, Kuppuswamy Subramaniam, Melanie A. Dunn, Geraldine Seydoux |
Plant growth homeostasis is controlled by the Arabidopsis BON1 and BAP1 genes.(Statistical Data Included) | Biological sciences | Gerald R. Fink, Jian Hua, Paula Grisafi, Shu-Hua Cheng |
Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors.(Statistical Data Included) | Biological sciences | Stuart H. Orkin, Silvio H. Litovsky, John D. Crispino, Maya B. Lodish, Beth L. Thurberg, Tucker Collins, Jeffery D. Molkentin |
Protein secretion and the pathogenesis of bacterial infections.(Statistical Data Included) | Biological sciences | Vincent T. Lee, Olaf Schneewind |
Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes.(Statistical Data Included) | Biological sciences | Said Sif, Andrew J. Saurin, Anthony N. Imbalzano, Robert E. Kingston |
Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. | Biological sciences | Jerry W. Shay, Woodring E. Wright, Ruben D. Ramirez, Carmela P. Morales, Brittney-Shea Herbert, Jeffrey M. Rohde, Christina Passons |
RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site.(Statistical Data Included) | Biological sciences | Anna Malkova, Laurence Signon, Christopher B. Schaefer, Maria L. Naylor, James F. Theis, Carol S. Newlon, James E. Haber |
RapA, a bacterial homolog of SWI2/SNF2, stimulates RNA polymerase recycling in transcription.(Statistical Data Included) | Biological sciences | Ding Jun Jin, Maxim V. Sukhodolets, Julio E. Cabrera, Huijun Zhi |
Reconstitution of recombinant chromatin establishes a recruitment for histone-tail modifications during chromatin assembly and transcription. | Biological sciences | Danny Reinberg, Alejandra Loyola, Gary LeRoy, Yuh-Hwa Wang |
Recruitment of HU by piggyback: a special role of GalR in repressosome assembly.(Statistical Data Included) | Biological sciences | Sudeshna Kar, Sankar Adhya |
Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain.(Statistical Data Included) | Biological sciences | Brian Hare, Peter Schmidt, Patricia Hidalgo, Aseem Z. Ansari, Natasha Simkovich, Susan Farrell, Eu Ji Shin, Mark Ptashne, Gerhard Wagner |
Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. | Biological sciences | Randall S. Johnson, Richard A. Firtel, Sudhasri Mohanty, Susan Lee, Nagendra Yadava, Marian Dealy |
Regulation of cyclin D2 gene expression by the Mrc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter.(Statistical Data Included) | Biological sciences | Caroline Bouchard, Oliver Dittrich, Astrid Kiermaier, Karen Dohmann, Annette Menkel, Martin Eilers, Bernhard Luscher |
Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family.(Statistical Data Included) | Biological sciences | Gary Ruvkun, Sarah B. Pierce, Michael Costa, Robert Wisotzkey, Sharmila Devadhar, Sheila A. Homburger, Andrew R. Buchman, Kimberly C. Ferguson, Jonathan Heller, Darren M. Platt, Amy A. Pasquinelli, Leo X. Liu, Stephen K. Doberstein |
Regulation of gene expression by the small GTPase Rho through the ERK6 (p38(gamma)) MAP kinase pathway.(Statistical Data Included) | Biological sciences | J. Silvio Gutkind, Maria Julia Marinissen, Mario Chiariello |
Regulation of translation initiation by FRAP/mTOR.(Statistical Data Included) | Biological sciences | Nahum Sonenberg, Anne-Claude Gingras, Brian Raught |
Requirement for math5 in the development of retinal ganglion cells. | Biological sciences | Randy L. Johnson, Steven W. Wang, Byong Su Kim, Kan Ding, Huan Wang, Dantong Sun, William H. Klein, Lin Gan |
Requirement of the JIP1 scaffold protein for stress-induced JNK activation.(c-Jun N-terminal kinase)(Statistical Data Included) | Biological sciences | Alan J. Whitmarsh, Roger J. Davis, Michael Appel, Richard A. Flavell, Stephen N. Jones, Chia-Yi Kuan, Norman J. Kennedy, Nyaya Kelkar, Tarik F. Haydar, John P. Mordes, Aldo A. Rossini, Pasko Rakic |
RNA interference - 2001. | Biological sciences | Phllip A. Sharp |
RNA interference is mediated by 21- and 22-nucleotide RNAs.(Statistical Data Included) | Biological sciences | Sayda M. Elbashir, Winfried Lendeckel, Thomas Tuschl |
Robertson's Mutator transposons in A. thaliana are regulated by the chromatin-remodeling gene Decrease in DNA Methylation (DDM1).(Arabidopsis thaliana)(Statistical Data Included) | Biological sciences | Robert A. Martienssen, Tatjana Singer, Cristina Yordan |
Role of Dlx6 in regulation of an endothelin-1-dependent dHAND branchial arch enhancer.(Statistical Data Included) | Biological sciences | James A. Richardson, Eric N. Olson, Jeroen Charite, David G. McFadden, Giorgio Merlo, Giovanni Levi, David E. Clouthier, Masashi Yanagisawa |
Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans.(Cryptococcus neoformans)(Statistical Data Included) | Biological sciences | Arturo Casadevall, Chiara Luberto, Dena L. Toffaletti, Elizabeth A. Wills, Stephanie C. Tucker, John R. Perfect, Yusuf A. Hannun, Maurizio Del Poeta |
Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites.(Statistical Data Included) | Biological sciences | Robert E. Johnson, Lajos Haracska, Satya Prakash, Louise Prakash, Ildiko Unk, Erik Johansson, Peter M.J. Burgers |
SAGA is an essential in vivo target of the yeast acidic activator Ga14p.(Statistical Data Included) | Biological sciences | Michael R. Green, Sukesh R. Bhaumik |
Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein.(Statistical Data Included) | Biological sciences | Shigeaki Kato, Myles Brown, Tetsuro Yahata, Wenlin Shao, Hideaki Endoh, Jingyung Hur, Kathryn R. Coser, Huiping Sun, Yoshitaka Ueda, Kurt J. Isselbacher, Toshi Shioda |
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation.(Statistical Data Included) | Biological sciences | Fang-Tsyr Lin, Weei-Chin Lin, Joseph R. Nevins |
Sequential actions of BMP receptors control neural precursor cell production and fate.(bone morphogenetic proteins)(Statistical Data Included) | Biological sciences | Sang-Hun Lee, Lorenz Studer, David M. Panchision, James M. Pickel, Patricia A. Turner, Thomas G. Hazel, Ronald D.G. McKay |
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation.(Statistical Data Included) | Biological sciences | Hung-Ying Kao, Michael Downes, Ronald M. Evans, Wen Xie, Yanhong Shi, Pater Ordentlich, Chih-Cheng Tsai, Michelle Hon |
Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN. | Biological sciences | Jeffrey L. Wrana, Kunxin Luo, Shannon L. Stroschein, Shirin Bonni |
SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice. | Biological sciences | Robyn Starr, Douglas J. Hilton, Warren S. Alexander, Geoffrey J. Lindeman, Sergio Wittlin, Hania Lada, Matthew J. Naylor, Margaret Santamaria, Jian-Guo Zhang, Christopher J. Ormandy, Jane Visvader |
Specific tracheal migration is mediated by complementary expression of cell surface proteins.(Statistical Data Included) | Biological sciences | Jordi Casanova, Muriel Boube, Maria D. Martin-Bermudo, Nicholas H. Brown |
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation.(Statistical Data Included) | Biological sciences | Michael S. Brown, Joseph L. Goldstein, Iichiro Shimomura, Morihiro Matsuda, Bobby S. Korn, Robert E. Hammer, Young-Ah Moon, Ryutaro Komuro, Jay D. Horton |
Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism.(Statistical Data Included) | Biological sciences | Olivier Vincent, Robert Townley, Sergei Kuchin, Marian Carlson |
Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex.(Statistical Data Included) | Biological sciences | Cathie M. Pfleger, Marc W. Kirschner, Ethan Lee |
Suppression of cap-dependent translation in mitosis.(Statistical Data Included) | Biological sciences | Nahum Sonenberg, Stephane Pyronnet, Josee Dostie |
SWITCH1(SWI1): a novel protein required for the establishment of sister chromatid cohesion and for bivalent formation at meiosis.(Statistical Data Included) | Biological sciences | Raphael Mercier, Daniel Vezon, Erika Bullier, Juan C. Motamayor, Aurelie Sellier, Francois Lefevre, Georges Pelletier, Christine Horlow |
Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD.(Statistical Data Included) | Biological sciences | David C. Schultz, Josh R. Friedman, Frank J. III. Rauscher |
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.(Statistical Data Included) | Biological sciences | Elaine Fuchs, Bradley J. Merrill, Uri Gat, Ramanuj DasGupta |
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm.(Statistical Data Included) | Biological sciences | Alex Vassilev, Kotaro J. Kaneko, Hongjun Shu, Yingming Zhao, Melvin L. DePamphilis |
Temporal and spatial regulation of Rho-type guanine-nucleotide exchange factors: the yeast perspective.(Review) | Biological sciences | Marie-Pierre Gulli, Matthias Peter |
Temporal regulation of a paired-like homeodomain repressor/TLE corepressor and a related activator is required for pituitary organogenesis.(Statistical Data Included) | Biological sciences | Michael G. Rosenfeld, Jeremy S. Dasen, Juan-Pedro Martinez Barbera, Thomas S. Herman, Shawn O'Connell, Lorin Olson, BongGun Ju, Jessica Tollkuhn, Sung Hee Baek, David W. Rose |
Terminal proteins essential for the replication of linear plasmids and chromosomes in Streptomyces.(Statistical Data Included) | Biological sciences | Stanley N. Cohen, Kai Bao |
TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3.(Statistical Data Included) | Biological sciences | Dong Liu, Brian L. Black, Rik Derynck |
The 19S complex of the proteasome regulates nucleotide excision repair in yeast.(Statistical Data Included) | Biological sciences | |
The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor. | Biological sciences | Yanzhen Cui, Renee Hackenmiller, Linnea Berg, francois Jean, Takuya Nakayama, Gary Thomas, Jan L. Christian |
The antibacterial arm of the Drosophila innate immune response requires an I(kappa)B kinase.(Statistical Data Included) | Biological sciences | Yiran Lu, Louisa P. Wu, Kathryn V. Anderson |
The Arabidopsis HOS1 gene negatively regulates cold signal transduction and encodes a RING finger protein that displays cold-regulated nucleo-cytoplasmic partitioning.(Statistical Data Included) | Biological sciences | Hojoung Lee, Liming Xiong, Zhizhong Gong, Manabu Ishitani, Becky Stevenson, Jian-Kang Zhu |
The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesis. | Biological sciences | Jeonghyeon Park, Sudeesha Kunjibettu, Steven B. McMahon, Michael D. Cole |
The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint.(Statistical Data Included) | Biological sciences | Andrew W. Murray, Sue Biggins |
The chimeric leucine-rich repeat/extension cell wall protein LRX1 is required for root hair morphogenesis in Arabidopsis thaliana.(Statistical Data Included) | Biological sciences | Christoph Ringli, Beat Keller, Nicolas Baumberger |
The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis.(Statistical Data Included) | Biological sciences | Leonie M. Quinn, Anabel Herr, Thomas J. McGarry, Helena Richardson |
The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family.(Statistical Data Included) | Biological sciences | Kumar L. Hari, Kevin R. Cook, Gary H. Karpen |
The expanding role of mitochondria in apoptosis.(Statistical Data Included) | Biological sciences | Xiaodong Wang |
The extrusion-capture model for chromosome partitioning in bacteria.(Statistical Data Included) | Biological sciences | Katherine P. Lemon, Alan D. Grossman |
The eyeless homeodomain is dispensable for eye development in Drosophila.(Statistical Data Included) | Biological sciences | Claudio Punzo, Shoichiro Kurata, Walter J. Gehring |
The fasciated ear2 gene encodes a leucine-rich repeat receptor-like protein that regulates shoot meristem proliferation in maize.(Statistical Data Included) | Biological sciences | David Jackson, Sarah Hake, Fumio Taguchi-Shiobara, Zhuang Yuan |
The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor.(Statistical Data Included) | Biological sciences | Gregory B. Potter, Gerard M. J. Beaudoin III, Cynthia L. DeRenzo, Joanna M. Zarach, Steve H. Chen, Catherine C. Thompson |
The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis. | Biological sciences | W. Tony Parks, Anita B. Roberts, Dug Keum Lee, Seok Hee Park, Youngsuk Yi, Shin-Geon Choi, Cecile Lee, HyeSeong Cho, Mark P. de Caestecker, Yosef Shaul, Seong-Jin Kim |
The lac operator-repressor system is functional in the mouse.(Statistical Data Included) | Biological sciences | Carolyn A. Cronin, Wendy Gluba, Heidi Scrable |
The languages of bacteria.(Statistical Data Included) | Biological sciences | Stephan Schauder, Bonnie L. Bassler |
The loop domain of heat shock transcription factor 1 dictates DNA-binding specificity and responses to heat stress.(Statistical Data Included) | Biological sciences | San-Gun Ahn, Phillip C.C. Liu, Katya Klyachko, Richard I. Morimoto, Dennis J. Thiele |
The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes.(Statistical Data Included) | Biological sciences | Qin Feng, Yi Zhang |
The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis.(Statistical Data Included) | Biological sciences | Brigid L.M. Hogan, Tsutomu Kume, HaiYan Jiang, Jolanta M. Topczewska |
The neuron-specific RNA-binding protein ELAV regulates neuroglian alternative splicing in neurons and binds directly to its pre-mRNA.(Statistical Data Included) | Biological sciences | Michael J. Lisbin, Ian Qiu, Kalpana White |
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44.(Statistical Data Included) | Biological sciences | Helen Morrison, Larry S. Sherman, James Legg, Fatima Banine, Clare Isacke, Carrie A. Haipek, David H. Gutmann, Helmut Ponta, Peter Herrlich |
The NPK1 mitogen-activated protein kinase kinase kinase is a regulator of cell-plate formation in plant cytokinesis. | Biological sciences | Ryuichi Nishihama, Masaki Ishikawa, Satoshi Araki, Takashi Soyano, Tetsuhiro Asada, Yasunori Machida |
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development.(Statistical Data Included) | Biological sciences | Ali H. Brivanlou, Eva Reissmann, Henrik Jornvall, Andries Blokzijl, Olov Andersson, Chebei Change, Gabriella Minchiotti, M. Graziella Persico, Carlos F. Ibanez |
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor. | Biological sciences | Matthias Wilm, Adrian Bird, Brian Hendrich, Anna Prokhortchouk, Helle Jorgensen, Alexei Ruzov, Georgii Georgiev, Egor Prokhortchouk |
The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4.(Statistical Data Included) | Biological sciences | Michael L. Stitzel, Robert Durso, Joseph C. Reese |
The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo.(Statistical Data Included) | Biological sciences | Yasuo Sakai, Chikara Meno, Hideta Fujii, Jinsuke Nishino, Hidetaka Shiratori, Yukio Saijoh, Janet Rossant, Hiroshi HAmada |
The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures.(Statistical Data Included) | Biological sciences | Pierre Chambon, Suzan Abu-Abed, Pascal Dolle, DAniel Metzger, Barbara Beckett, Martin Petkivich |
The RNA- binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis.(Statistical Data Included) | Biological sciences | Stephanie E. Mohr, Simon T. Dillon, Robert E. Boswell |
The RssB response regulator directly targets sigma(super.S) for degradation by ClpXP.(Statistical Data Included) | Biological sciences | Michael R. Maurizi, YanNing Zhou, Susan Gottesman, Joel R. Hoskins, Sue Wickner |
The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Ga14.(Saccharomyces)(Statistical Data Included) | Biological sciences | Fred Winston, Erica Larschan |
The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.(Saccharomyces)(Statistical Data Included) | Biological sciences | Matthias Wilm, A. Francis Stewart, W.W.M. Pim Pijnappel, Daniel Schaft, Assen Roguev, Anna Shevchenko, Hille Tekotte, Guillaume Rigaut, Bertrand Seraphin, Rein Aasland |
The set1(Delta) mutation unveils a novel signaling pathway related by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes.(Statistical Data Included) | Biological sciences | Giovanna Lucchini, Maria Pia Longhese, Vera Schramke, Holger Neecke, Vanessa Brevet, Yves Corda, Eric Gilson, Vincent Geli |
The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.(chromatin assembly factor 1)(Statistical Data Included) | Biological sciences | Sebastiaan H. Meijsing, Ann E. Ehrenhofer-Murray |
The Sir1 protein's association with a silenced chromososome domain.(Statistical Data Included) | Biological sciences | Kelly A. Gardner, Catherine A. Fox |
The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II.(Statistical Data Included) | Biological sciences | Yaxin Yu, David J. Stillman, Leena T. Bhoite |
The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle.(Statistical Data Included) | Biological sciences | Meinrad Busslinger, Wolfram Jochum, Yann Barrandon, Tammy Ellis, Laure Gamvardella, Markus Horcher, Stefan Tschanz, Janine Capol, Paula Bertram |
The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse.(Statistical Data Included) | Biological sciences | Yasuo Sakai, Chikara Meno, Hidetaka Shiratori, Yukio Saijoh, Masamichi Yamamoto, Kyoko Mochida, Yayoi Ikawa, Hiroshi Hamada |
The transcription factor Sox10 is a key regulator of peripheral glial development.(Statistical Data Included) | Biological sciences | Klaus-Armin Nave, Stefan Britsch, Derk E. Goerich, Dieter Riethmacher, Reto I. Peirano, Moritz Rossner, Carmen Birchmeier, Michael Wegner |
The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryo.(Statistical Data Included) | Biological sciences | Toy Sudipto, Christian (German philosopher) Wolff, Philip W. Ingham |
The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish.(Statistical Data Included) | Biological sciences | Lilianna Solnica-Krezel, Jacek Topczewski, Brigid L.M. Hogan, Tsutomu Kume, Jolanta M. Topczewska, Alena Shostak |
The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseases.(Statistical Data Included) | Biological sciences | Alan R. Lehman |
The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1.(MOZ, Ybf2/Sas3, Sas2 and TIP60)(Statistical Data Included) | Biological sciences | Rolf Sternglanz, Jerry L. Workman, Shigehiro Osada, Ann Sutton, Nemone Muster, Christine E. Brown, John R. Yates III |
The yeast Xrs2 complex functions in S phase checkpoint regulation.(Statistical Data Included) | Biological sciences | Stephen P. Jackson, Damien D'Amours |
TIF1(beta) functions as a coactivator for C/EBP(beta) and is required for induced differentiation in the myelomonocytic cell line U937.(Statistical Data Included) | Biological sciences | John W. Rooney, Kathryn L. Calame |
Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia.(Statistical Data Included) | Biological sciences | Siew-Lan Ang, Klaus H. Kaestner, Mark A. Magnuson, Franz M. Matschinsky, Newman J. Sund, Marko Z. Vatamaniuk, Melissa Casey, Doris A. Stoffers |
Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA.(Statistical Data Included) | Biological sciences | Frederic Charron, Lynda Robitaille, Mona Nemer, George Tsimiklis, Mathieu Arcand, Qiangrong Liang, Jeffrey D. Molkentin, Sylvain Meloche |
Tn7 recognizes transposition target structures associated with DNA replication using the DNA-binding protein TnsE.(Statistical Data Included) | Biological sciences | Joseph E. Peters, Nancy L. Craig |
Topoisomerase IV, alone, unknots DNA in E. coli.(Statistical Data Included) | Biological sciences | Richard W. Deibler, Sonia Rahmati, E. Lynn Zechiedrich |
Transcriptional activation: risky business. | Biological sciences | William P. Tansey |
Transcriptional regulation of the Drosophila gene zen by competing Smad and Brinker inputs. | Biological sciences | Christine Rushlow, Pamela F. Colosimo, Meng-chi Lin, Mu Xu, Nikolai Kirov |
Transcriptional repression: the long and the short of it.(Review) | Biological sciences | Albert J. Courey, Songtao Jia |
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails.(Statistical Data Included) | Biological sciences | Danny Reinberg, Yi Zhang |
Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift.(Statistical Data Included) | Biological sciences | Francois Taddei, Miroslav Radman, Damien Bregeon, Vincent Colot |
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. | Biological sciences | Xinsheng Gao, Pan Duojia |
Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily.(Statistical Data Included) | Biological sciences | Robert B. Chadwick, Roderick Bronson, George Steele-Perkins, Wei Fang, Xiao-Hong Yang, Miereille Van Gele, Tobias Carling, Jian Gu, Inge M. Buyse, Jonathon A. Fletcher, Jinsong Liu, Albert De la Chapelle, Xiao-kun Zhang, Frank Speleman, Shi Huang |
Tumorigenesis in mice carrying a truncating Brca1 mutation.(Statistical Data Included) | Biological sciences | Thomas Ludwig, Peter R. Fisher, Shridar Ganesan, Argiris Efstratiadis |
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. | Biological sciences | Justine A. Melo, Jen Cohen, David P. Toczyski |
Two enhancers and one silencer located in the introns of regA control somatic cell differentiation in Volvox carteri. | Biological sciences | Klaus Stark, David L. Kirk, Rudiger Schmitt |
Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling.(Statistical Data Included) | Biological sciences | Jeffrey D. Axelrod |
Using viral species specificity to define a critical protein/RNA interaction surface.(Statistical Data Included) | Biological sciences | Bryan R. Cullen, Glen A. Coburn, Heather L. Wiegand, Yibin Kang, Dona N. Ho, Millie M. Georgiadis |
vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain.(maturity-onset diabetes of the young, type V)(glomerulocystic kidney disease)(Statistical Data Included) | Biological sciences | Nancy Hopkins, Zhaoxia Sun |
Whi3 binds the mRNA of the G(sub)1 cyclin CLN3 to modulate cell fate in budding yeast. | Biological sciences | Tom Volpe, Eloi Gari, Hongyin Wang, Gallego Carme, Bruce Futcher, Marti Aldea |
Wnt antagonism initiates cardiogenesis in Xenopus laevis. | Biological sciences | Valerie A. Schneider, Mark Mercola |
Wnt signals from the neural tube block ectopic cardiogenesis. | Biological sciences | Eldad Tzahor, Andrew B. Lassar |
Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1.(Statistical Data Included) | Biological sciences | Lifeng Xu, Diane Pennica, Arnold J. Levine, Weikang Tao, Robert F. Kalejta |
Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning.(Statistical Data Included) | Biological sciences | Stephen L. Nutt, Kevin S. Dingwell, Christine E. Holt, Enrique Amaya |
Yak1p, a DYRK family kinase, translocates to the nucleus and phosphorylates yeast Pop2p in response to a glucose signal.(Statistical Data Included) | Biological sciences | Hisao Moriya, Yuki Shimizu-Yoshida, Akira Omori, Shintaro Iwashita, Mariko Katoh, Akira Sakai |
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