Nature Biotechnology 2000 - Abstracts

Nature Biotechnology 2000
TitleSubjectAuthors
A chamber of hope for hemophilia.BusinessStephen W. Pipe, Randal J. Kaufman
A chamber of hope for hemophilia.BusinessRandal J. Kaufman, Steven W. Pipe
A colorimetric assay for rapid screening of antimicrobial peptides.BusinessSofiya et al Kolusheva
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand.BusinessYoung-Yun et al Kong
A fluorescent indicator for visualizing aAMP-induced phosphorylation in vivo.BusinessYasuo et al Nagai
Agrbiotech and world food security - threat or boon?(Commentary)(Brief Article)BusinessRichard Gilmore
AHP sells Immunex stake.Business 
A kaleidoscope of carotenoids.(Illustration)BusinessJoseph M. Jez, Joseph P. Noel
Analysis of vertebrate SCL loci identifies conserved enhancers.(Brief Article)Business 
Anchored multiplex amplification on a microelectronic chip array.(Brief Article)Business 
A network of protein-protein interactions in yeast.BusinessPeter Uetz, Stanley Fields, Benno Schwikowski
A new microvolume technique for bioaffinity assays using two-photon excitation.BusinessPekka Hanninen, Aleksi Soini, Niko Meltota, Juhani Soini, Jori Soukka, Erkki Soini
An induction gene trap for identifying a homeoprotein-regulated locus.Business 
Antibacterial and antifungal drug discovery: companies are racing to keep pace with the emergence of drug-resistant microorganisms.(Brief Article)Business 
Applications of display technology in protein analysis.BusinessMin Li
Arthritis: the aging population of developed countries are likely to present a growing market for arthritis therapies.(Brief Article)Business 
Asthma.(Brief Article)Business 
A taste test for proteases.BusinessBenn Dunn
a T-cell-selective interleukin 2 mutein exhibits potent antitumor activity and is well tolerated in vivo.BusinessArmen B. Shanafelt
A tissue of cells.BusinessDavid L. Porter, Stephen G. Emerson
A ubiquitin-based tagging system for controlled modulation of protein stability.Businesset al, Jeffrey H. Stack
Autoimmune disease: rapid progress in our understanding of immune function promises more effective treatments for autoimmune disorders.(Brief Article)Business 
Bioinformatics: companies are selling research software to a small number of rich clients or offering services to researchers over the Internet.(Brief Article)Business 
Biological software for materials engineering.(use of biological molecules in materials engineering)(Illustration)BusinessRoberto Cingolani
Biopharmaceutical benchmarks.(Illustration)BusinessGary Walsh
Bioprospecting deal OK.Business 
Biotechnology and the European public.BusinessNick et al Gaskell
Biotechnology becomes the new dot com.(Brief Article)Business 
Biotechnology venture capital booms in Japan.BusinessAsako Saegusa
Blue Gene to study folding.Business 
Breeding of retroviruses by DNA shuffling for improved stability and processing yields.Businesset al, Sharon K. Powell
British Biotech redefines itself.BusinessSylvia Davidson
Bt corn kills monarch.Business 
Business models in biotech: companies with technology platforms that address only a tiny part of the discovery process risk becoming optional or redundant accessories.(Brief Article)BusinessStelios Papadopoulos
CAncer multidrug resistance: progress in understanding the molecular basis drug resistance in cancer promises more effective treatments.(Brief Article)Business 
Cardiovascular disease: prognostic/diagnostic testing and a raft of new drug targets from genomics promise to transform cardiovascular medicine.(Brief Article)Business 
Changing attitudes to biotechnology in Japan.BusinessDarryl Macer, Mary Ann Chen Ng
Chiron buys PathoGenesis.Business 
Cloning and its discontents; a Canadian perspective.BusinessEdna F. Einsiedel
Cold fusion for eggs.Business 
Combinational chemistry gives cell biology some muscle.BusinessDennis G. Hall
Combinational chemistry gives cell biology some muscle.BusinessDennis G. Hall
Combinatorial chemistry: to avoid becoming a commodities industry, combinatorial chemistry companies are broadening their technology base.(Brief Article)Business 
Commitment to the B-lymphoid linage depends on the transcription factor Pax5.BusinessStephen L. Nutt, Barry Heavey, Antonius G. Rolink, Meinrad Busslinger
Competitive business intelligence gathering and analysis: intelligence systems are providing an answer to the avalanche of information in science and business.(Brief Article)Business 
Creating molecular clues to uncover gene function.(Brief Article)BusinessAlan P. Wolffe, Benoit P. Leblanc
Cytokine production in motor neurons by poliovirus replicon vector gene delivery.BusinessAndrea et al Bledsoe
Data mining: a variety of software products and services are being introduced to analyze complex biological and chemical data in an intuitive and efficient manner.(Brief Article)Business 
Differentiating genomics companies: as the value of raw sequence data diminishes, genomics comapnies are evolving new competencies as providers of information, therapeutic products, or novel technology.BusinessRob James
Differentiating genomics companies.(As the value of raw sequence data diminishes, genomics companies are evolving new competencies as providers of information, therapeutic products, or novel technology.)(Brief Article)Business 
DNA cloning by homologous recombination in Escherichia coli.BusinessYouming Zhang, et al
Don't go there: Phil Plait's Bad Astronomy: www.badastronomy.com.(Brief Article)Business 
Dutch bill unlikely to revive industry.(Analysis)BusinessMarianne Heselmans
Eco-terrorism penalties.Business 
EC struggles to unravel regulations.Business 
Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal.BusinessOlfert Landt, Giovanna Cutrona, Elisabetta M. Carpaneto, Massimo Ulivi, Silvio Roncella, Manlio Ferrarini, Lidia C. Boffa
Efficient generation of human T cells from a tissue-engineered thymic organoid.Business 
Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.BusinessSang-Hun Lee, Nadya Lumelsky, Lorenz Studer, Jonathan M. Auerbach, Ron D. McKay
Efficient gene transfer to airway epithelium using recombinant Sendai virus.BusinessYoshikazu et al Yonemitsu
Efficient nonviral transfection of dendritic cells and their use for in vivo immunization.(Statistical Data Included)Businesset al, Alistair S. Irvine
Efforts to commercialize structural genomics may be limited.Business 
Electrochemical DNA analysis comes of age.(Brief Article)BusinessWerner G. Kuhr
Elevation of the provitamin A content of transgenic tomato plants.BusinessSusanne Romer, Paul D. Fraser, Joy W. Kiano, Cathie A. Shipton, Norihiko Misawa, Wolfgang Schuch, Peter M. Bramley
Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.BusinessBenjamin et al Reubinoff
Emerging themes in medicinal glycoscience.(Illustration)BusinessKathryn M. Koeller, Chi-Huey Wong
Engineering a mouse metallothionein on the cell surface of Ralstonia eutropha CH34 for immobilization of heavy metals in soil.BusinessMarc Valls, Silvia Atrian, Victor De Lorenzo, Luis A. Fernandez
Engineering herbicide-resistant maize using chimeric RNA/DNA oligonucleotides.BusinessTong Zhu, Mettenburg, David J. Peterson, Laura Tagliani, Chris L. Baszczynski
Engineering of an FGF-proteoglycan fusion protein with heparin-independent mitogenic activity.BusinessAtsuko Yoneda, Masahiro Asada, Yuko Oda, Masashi Suzuki, Toru Imamura
Engineering of bone grafts.BusinessLaura Niklason
Enhanced major histocompatibility complex class I-dependent presentation of antigens modified with cationic and fusogenic peptides.BusinessReiner Laus, Thomas J. Graddis, Itzhak Hakim, Damir Vidovic
Enhancement of transfection by physical concentration of DNA at the cell surface.(Illustration)(Statistical Data Included)BusinessDan Luo, W. Mark Saltzman
Enhancement of tumor necrosis factor Alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13).BusinessFlavio et al Curnis
Environmentally safe production of 7-aminodeacetoxycephalosporanic acid (7-ADCA) using recombinant strains of Acremonium chrysogenum.(Illustration)(Statistical Data Included)BusinessJavier Velasco, Jose Luis Adrio, Miguel Angel Moreno, Bruno Diez, Gloria Soler, Jose Luis Barredo
EPA rejects Greenpeace.Business 
Ephemeral gene medicine for the brain.BusinessJaques Mallet, Che Serguera
Equipping scientists for the new biology.(Commentary)(Brief Article)BusinessRuedi Aebersold, Leroy E. Hood, Julian D. Watts
EU biosciences panel.Business 
EU GMO applications continue to rot.BusinessMarianne Heselmans
European exploitation of biotechnology-do government policies help?BusinessJacqueline Senker, Christien Enzing, Pierre-Benoit Joly, Thomas Reiss
European patent oppositions and biotechnology.BusinessKristina V.J. Cornish
EU's new orphan drug regulations.Business 
Expanding the AAV package.BusinessRichard Jude Samulski
Exploring genome space.BusinessOgnjenka Goga et al Vukmirovic
FDA, researchers consider first transgenic fish.BusinessEric niiler
FDA, researchers consider first transgenic fish.(Brief Article)Business 
Financing bonanza set to continue.BusinessSilvia Davidson
First round to Amgen in EPO battle.BusinessDebra Robertson
From the high Andes: European Southern Observatory: www.eso.org.(Brief Article)Business 
Function-based isolation of novel enzymes from a large library.(Brief Article)BusinessMark J. et al olsen
Fungal pathogen protection in potato by expression of a plant defensin peptide.Businesset al, Ai-Guo Gao
Gene delivery from a DNA controlled-release stent in porcine coronary arteries.BusinessBruce D. Klugherz, Peter L. Jones, Xiumin Cui, Weiliam Chen, Nicholas F. Meneveau, Suzanne DeFelice, Jeanne Connolly, Robert L. Wilensky, Robert J. Levy
Gene delivery from a DNA controlled-release stent in porcine coronary arteries.BusinessBruce D. et al Klugherz
Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead assays.BusinessSydney Brenner, Maria Johnson, John Bridgham, George Golda, David H. Lloyd, Davida Johnson, Shujun Luo, Sarah McCurdy, Michael Foy, Mark Ewan, Rithy Roth, Dave George, Sam Eletr, Glenn Albrecht, Eric Vermaas, Steven R. Williams, Keith Moon, Timothy Burcham, Michael Pallas, Robert B. DuBridge, James Kirchner, Karen Fearon, Mao-Jen-i, Kevin Corcoran
Gene therapy buy.Business 
Gene therapy guidelines.Business 
Genetic selection for dissociative inhibitors of designated protein-protein interactions.(Illustration)(Statistical Data Included)BusinessSang-Hyun Park, Ronald T. Raines
Genome-directed primers for selective labeling of bacterial transcripts for DNA microarray analysis.BusinessAdel M. Talaat, Preston Hunter, Stephen Albert Johnston
Genomic integration and gene expression by a modified adenoviral vector.(Brief Article)Business 
Genomic integration and gene expression by modified adenoviral vector.BusinessChangyu et al Zheng
Genomics, gene expression and DNA arrays.BusinessElizabeth A. Winzeler, David J. Lockart
German health minister calls time out for Bt maize.BusinessEllen Peerenboom
German Health Minister calls time out for Bt maize.(Brief Article)BusinessEllen Peerenboom
Getting genes where we want them.BusinessLaura Niklason
GM food regulatory terms debated.BusinessAsako Saegusa
GMO roundup.Business 
Golden handouts on the way.Business 
G-protein-coupled receptors as targets for gene transfer vectors using natural small-molecule ligands.BusinessSilvia M. Kreda, Raymond J. Pickles, Eduardo R. Lazarowski, Richard C. Boucher
Green ag minister wreaks havoc on Italy's agbiotech.BusinessAnna Meldolesi
Guilford halts Gliatech deal.Business 
Heritable gene silencing in Drosophila using double-stranded RNA.(Illustration)(Statistical Data Included)BusinessJason R. Kennerdell, Carthew Richard W.
HGS targets patent-expiring drugs.(Analysis)BusinessTom Hollon
High-affinity TCRs.Business 
High-performance affinity beads for identifiying drug receptors.(Illustration)(Statistical Data Included)BusinessNoriaki Shimizu, Kotaro Sugimoto, Jianwei Tang, Takeyuki Nishi, Iwao Sato, Masaki Hiramoto, Shin Aizawa, Mamoru Hatakeyama, Reiko Ohba, Hideaki Hatori, Tatsufumi Yoshikawa, Fumihiko Suzuki, Akira Oomori, Hirotoshi Tanaka, Haruma Kawaguchi, Hajime Watanabe, Hiroshi Handa
Human fly bites rub Celera.Business 
Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin.BusinessT. ashton et al Cropp
Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase.BusinessBas van Steensel, Steven Henikoff
Imaging Alzheimer's amyloid.(cerebral amyloid protein accumulation)BusinessDennis J. Selkoe
Immunoprophylaxis in fish by injection of mouse antibody genes.BusinessNiels Lorenzen, Pauline M. Cupit, Katja Einer-Jensen, Ellen Lorenzen, Peter Ahrens, Christopher J. Secombes, Charles Cunningham
Immunoprophylaxis in fish by injection of mouse antibody genes.BusinessNiels et al Lorenzen
Immunostimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism.BusinessHearn Jay Cho, Kenji Takabayashi, Pei-Ming Cheng, Minh-Duc Nguyen, Maripat Corr, Stephen Tuck, Eyal Raz
Improving lycopene production in Escherichia coli by engineering metabolic control.BusinessWilliam J. Farmer, James C. Liao
Increasing galactose consumption by Saccharomyces cerevisiae through metabolic engineering of the GAL gene regulatory network.BusinessMark Johnston, Jens Nielsen, Simon Ostergaard, Lisbeth Olsson
Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complimentary vectors.BusinessHiroyuki Nakai, Theresa A. Storm, Mark A. Kay
In defense of complete genomes.BusinessJulian Parkhill
India okays Bt cotton.Business 
Induction of human cytotoxic T lymphocytes by artificial antigen-presenting cells.BusinessJean-Baptiste Latouche, Michel Sadelain
Internet chat damages biotechnology stocks.Business 
Intracellular trehalose improves the survival of cryopreserved mammalian cells.BusinessAli et al Erjogoglu
Intracellular trehalose improves the survival of cryopreserved mammalian cells.(Brief Article)Business 
Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine.BusinessOliver et al May
Investigation of gene therapy begins.(Brief Article)Business 
In vitro selection of signaling aptamers.BusinessSulay Jhaveri, Manjula Rajendran, Andrew D. Ellington
In vivo bypass of hemophila A coagulation defect by Factor XIIa implant.BusinessT. Ton-That et al Tung
In vivo bypass of hemophilia A coagulation defect by Factor XIIa implant.BusinessTung T. Ton-That, David Doron, Bette S. Pollard, John Bacher, Harvey B. Pollard
In vivo imaging of neuronal activation and plasticity in the rat brain by high resolution positron emission tomography (microPET).BusinessHarley I. Kornblum, Dalia M. Araujo, Alexander J. Annala, Keith J. Tatsukawa, Michael E. Phelps, Simon R. Cherry
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide.BusinessRichard J. Bartlett, Sabine Stockinger, Melvin M. Denis, William T. Bartlett, Luca Inverardi, T. T. Le, Nguyen thi Man, Glenn E. Morris, Daniel J. Bogan, Janet Metcalf-Bogan, Joe N. Kornegay
In vivo visualization of gene expression using magnetic resonance imaging.BusinessAngelique Y. et al Louie
Isis and antisense face crucial test without Novartis.BusinessAlan Dover
Italy toasts Sardinia with SharDNA.Business 
Japan banks on budget to boost biotechnology.(Brief Article)Business 
Japan's cloning law fails.Business 
Large-scale functional analysis using peptide or protein arrays.BusinessGerard Cagney, Alia Qureshi Emili
Laying hold on eternal life?(Researchers conducted studies on the relationship)(of cloning with telomere biology and aging.)BusinessIan Wilmut, John Clark, Calvin B. Harley
Lead validation platforms: a battery of screening systemsare under development talidate compounds for further development.(Brief Article)Business 
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays.BusinessKirstin et al Lindblad-Toh
MAG's demise signals trouble for bioinformatics firms.BusinessPotter Wickware
MAG's demise signals trouble for bioinformatics firms.(Brief Article)Business 
Malaria: together with major international initiatives, companies are launching an offense against the world's most deadly parasitic disease.(Brief Article)Business 
Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts.(Brief Article)BusinessYoshimi et al Kuroiwa
Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts.(Brief Article)BusinessYoshimi Kuroiwa
Maximizing profits through intelligent planning and implementation.BusinessJohn P. Isacson
Measuring the peptides in individual organelles with mass spectrometry.(Brief Article)Business 
Metabolic engineering of astaxanthin production in tobacco flowers.(Illustration)(Statistical Data Included)Businessvarda Mann, Mark Harker, Iris Pecker, Joseph Hirschberg
Metabolite profling for plant functional genomics.BusinessThomas Altmann, Oliver Fiehn, Joachim Kopka, Peter Dormann, Richard N. Tretheway, Lothar Willmitzer
Micrjoarray fabrication with covalent attachment of DNA using Bubble Jet technology.BusinessTadashi et al Okamoto
Microbes with a mettle for bioremediation.BusinessJon R. Lloyd, Derek R. Lovley
Micropia: the Institute for Genomic Research: www.tigr.org.(Brief Article)Business 
Money talks: Recombinant capital: www.recap.com/mainweb.nsf.(Brief Article)Business 
Monsanto to merge with P&U.(Brief Article)Business 
Moving the gene patent debate forward.(A framework for achieving compromise between industry and civil society.)BusinessE. Richard Gold
Mysteries for teachers: Access excellence: www.accessexcellence.com.(Brief Article)Business 
Neuer Markt drives IPOs in Europe.BusinessIngeborg Spillman-Furst
New paths to pain relief: a better understanding of the mechanisms by which pain signals are relayed in the nervous system is paving the way for novel treatments.BusinessVicki Brower
News from on high: Spaceref.com.(Brief Article)Business 
New tools for human developmental biology.BusinessKevin D'Amour, Fred H. Gage
New tools for human developmental biology.(Brief Article)BusinessKevin D'Amour, Fred H. Gage
Novel hydroxycarotenoids with improved antioxidative properties produced by gene combination in Escherichia coli.(Illustration)(Statistical Data Included)BusinessManuela Albrecht, Shinichi Takaichi, Sabine Steiger, Zheng-Yu Wang, Gerhard Sandmann
Observant opposition: Genewatch: www.genewatch.org.(Brief Article)Business 
Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5.BusinessTajib Mirzabekov, Harry Kontos, Michael Farzan, Wayne Marasco, Joseph Sodroski
PERV data renew xeno debate.Business 
Phage display of peptide epitopes from HIV-1 elicits strong cytolytic responses.(Illustration)(Statistical Data Included)BusinessPiergiuseppe De Berardinis, Rossella Sartorius, Cristina Fanutti, Richard N. Perham, Giovanna Del Pozzo, John Guardiola
Pharmacogenetics and the practice of medicine.Business 
Pharmacogenomics: information on human genetic variance is only just beginning to be used in drug development.(Brief Article)Business 
Phytodetoxification of hazardous organomercurials by genetically engineered plants.BusinessScott P. et al Bizily
Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display.BusinessJozef Hanes, Christiane Schaffitzel, Achim Knappik, Andraes Pluckthun
Plants rendered herbicide-susceptible by cauliflower mosiac virus-elicited suppression of a 35S promotor-regulated transgene.BusinessNadia S. et al Al-Kaff
Porcine xenotransplants: will they fly?BusinessLars Olson
Preservation of mammalian cells-learning nature's tricks.BusinessJohn H. Crowe, Lois M. Crowe
Prevention of systemic lupus erythematosus in MRL/lpr mice by administration of an immunoglobin-binding peptide.BusinessMaria Marino, Menotti Ruvo
Probing proteoms; seeing the whole picture?(Brief Article)BusinessRichard D. Smith
Probing the proteasome pathway.BusinessAlfred L. Goldberg
Problem solving for tumor immunotherapy.BusinessHans-Georg Rammensee, Cecile Gouttefangeas
Production of cloned pigs from in vitro systems.(Brief Article)BusinessJeff et al Betthauser
Production of hepatitis B surface antigen in transgenic plants for oral immunization.BusinessLiz J. Richter, Yasmin Thanavala, Charles J. Arntzen, Hugh S. Mason
Production of hepatitis B surface antigen in transgenic plants for oral immunization.BusinessLiz J. Richter
Production of very-high-amylose potato starch by inhibition of SBE A and B.BusinessGerhard P. Schwall, Richard Safford, Roger J. Westcott, Roger Jeffcoat, Akash Tayal, Yong-Cheng Shi, Michael J. Gidley, Stephen A. Jobling
progress against HIV: the need for new treatments for AIDS is more urgent than ever.(Brief Article)Business 
Protein C may be sepsis solution.BusinessKen Garber
Protein function in the post-genomic era.BusinessDavid et al Eisenberg
Proteins emerge from disarray.BusinessRobert A. Irving, Peter J. Hudson
Proteomics to study genes and genomes.BusinessAkhilesh Pandey, Mattias Mann
Psst: biotech rumor mill: www.biofind.com/rumor.(Brief Article)Business 
Public biotech 99: the numbers.BusinessJohn Hodgson, Riku Lahteenmaki
Pulsed electric fields for selection of hematopoietic cells and depletion of tumor cell contaminants.(Illustration)(Statistical Data Included)BusinessRussell Foxall, David T. Scadden, David Dombkowski, Henry M. Eppich, Kate Gaynor, Nobuyuki Miura, Tao Cheng, Sandra Silva-Arrieta, Richard H. Evans, Joseph A. Mangano, Frederic I. Preffer
Rational design of cytotoxic T-cell inhibitors.BusinessAnna P. et al Tretiakova
Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo.(Brief Article)Business 
Reasonable no doubt: Reason: www.reason.com/bi/bi-gmf.html.(Brief Article)Business 
Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries.(complementarity-determining region)(Illustration)(Statistical Data Included)BusinessEskil Soderlind, Leif Strandberg, Pernilla Jirholt, Norihiro Kobayashi, Vessela Alexeiva, Anna-Maria Aberg, Anna Nilsson, Bo Jansson, Mats Ohlin, Christer Wingren, Lena Danielsson, Rolan Carlsson, Carl A.K. Borrabaeck
Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis.(Illustration)(Statistical Data Included)BusinessHong Zhang, Jesse Cook, Jeffrey Nickel, Rosie Yu, Kimberly Stecker, Kathleen Myers, Nicholas M. Dean
Removal of antibiotic resistance genes from transgenic tobacco plastids.BusinessSiriluk Iamtham, Anil Day
Removal of antibiotic resistance genes from transgenic tobacco plastids.BusinessAnil Day, Siriluck Iamtham
Replicative adenoviruses for cancer therapy.BusinessRamon Alemany, Cristina Balague, David T. Curiel
Research suggests importance of haplotypes over SNPs.BusinessSylvia Davidson
Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides.BusinessChristopher J. Wraight, Paul J. White, Sandra C. McKean, Rhys D. Fogarty, Daryl J. Venables, Ingrid J. Liepe, Stephanie R. Edmondson, George A. Werther
rFactor VIII deficit questioned.BusinessKen Garber
RNA expression analysis using a 30 base pair resolution Escherichia coli genome array.BusinessDouglas W. Selinger, et al
Roche's Taq patent invalid.Business 
Ruling favors Amgen.Business 
Scrutiny of gene therapy broadens, intensifies.BusinessJeffrey l. Fox
Selecting and maintaining a diverse T-cell repertoire.BusinessAnanda W. Goldrath, Michael J. Bevan
sensing proteins outside of the box.Business 
Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells.BusinessNico P. Dantuma, Kristina Lindsten, Rickard Glas, Marianne Jellne, Maria G. Masucci
Should companies set up databases in Europe?BusinessJasper A. Bovenberg
Signal transduction as a drug-discovery platform: mappping the key signaling molecules in bilchemical pathways will be central to future drug discovery efforts.(Brief Article)Business 
Silencing Morpheus awakens transgenes.BusinessVicki L. Chandler, Richard Jorgensen
Simultaneous stochastic sensing of divalent metal ions.BusinessOrit et al Braha
Small success for gene therapy.Business 
So many genomes, so little time.BusinessWebb Miller
Spleen necrosis virus-derived C-type retroviral vectors for gene transfer to quiescent cells.BusinessZahida Parveen, Anna Krupetsky, Martin Engelstadter, Klaus Cichutek, Roger J. Pomerantz, Ralph Dornburg
Stable correction of a genetic deficiency in human cells by an episome carrying a 115 kb genomic transgene.Businesset al, Richard Wade-Martins
Stable transformation of Erysiphe graminis, an obligate biotrophic pathogen of barley.(Brief Article)Business 
Stable transformation of Erysiphe graminus, an obligate biotrophic pathogen of barley.BusinessPushpalata et al Chaure
Staring at the sun: the Stanford Solar Center: solar-center.stanford.edu.(Brief Article)Business 
Status of genome projects for nonpathogenic bacteria and archaea.(Brief Article)BusinessKaren E. et al Nelson
Structural genomics and its importance for gene function analysis.BusinessJeffrey Skolnick, Jacquelyn S. Fetrow, Andrzej Kolinski
Structural genomics and its importance for gene function analysis.BusinessJeffrey et al Skolnick
Structural genomics deal.Business 
Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase.BusinessWutl et al Meng
Surface-displayed viral antigens on Salmonella carrier vaccine.BusinessJong-Soo Lee, Kwang-Soon Shin, Jae-Gu Pan, Chul-Joong Kim
Surrogate s-cells.Business 
Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.(Brief Article)Business 
Taking a census of mRNA populations with microbeads.BusinessSanjay Tyagi
Taming the uncultured.BusinessNicholas J. Talbot, Lisbeth Hamer
TAP expression provides a general method for improving the recognition of malignant cells in vivo.BusinessJudy Alimonti, Qian-Jin Zhang, Reinhard Gabathuler, Gregor Reid, Chen Susan S., Wilfred A. Jefferies
Targeted antigen delivery to antigen: presenting cells including dendritic cells by engineered Fas-mediated apoptosis.BusinessMichael Chattergoon
Targeting Alzheimer amyloid plaques in vivo.(Illustration)(Statistical Data Included)BusinessThomas M. Wengenack, Geoffry L. Curran, Joseph F. Poduslo
Target watching with a beady eye.BusinessMarkus Rudin
Testing Bt refuge strategies in the field.BusinessFred Gould
The challenges of in silico biology.(Viewing cells as systems)BusinessBernhard Palsson
The changing marketplace of bioinformatics.(The demand for more sophisticated bioinformatics solutions is expanding opportunities for biotechnology startups, but traditional IT companies are also moving into the market.)BusinessPaolo P. Saviotti, Marie-Angele deLooze, Sylvie Michelland, David Catherine
The dark side: the Bradford- SIPRI project: www.brad.ac.uk/acad/sbtwc.(Brief Article)Business 
The hair follicle as a gene therapy target.BusinessRobert M. Hoffman
The neighbors: the nine planets: seds.IpL.arizona.edu/billa/tnp.(Brief Article)Business 
The pharmacological basis of anti-IgE therapy.BusinessTse Wen Chang
The possibilities/perplexities of stem cells.BusinessEvan Y. Snyder, Angelo L. Vescovi
Therapy of mucosal candidiasis by expression of an anti-idiotype in human commensal bacteria.(Brief Article)BusinessConcetta et al Beninati
The single cell as a microplate well.(Brief Article)BusinessK. Dane Wittrup
The small world of metabolism.BusinessDavid A. Fell, Andreas Wagner
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.BusinessDavid M. et al Underhill
The use of single-nucleotide polymorphism maps in pharmacogenomics.BusinessJeanette J McCarthy, Rolf Hilfiker
The use of telomerized cells for tissue engineering.BusinessJerry W. Shay, E. Wright Woodring
Three-dimensional cellular development is essential for ex-vivo formation of human bone.BusinessSujata et al Kale
Tissue-engineered bone regeneration.BusinessHerve et el Petite
TnAraOut, A transposon-based approach to identify and characterize essential bacterial genes.BusinessNicholas Judson, John J. Mekalanos
Tobacco ribosomal DNA spacer element stimulates amplification and expression of heterologous genes.Businesset al, Nikolai Borisjuk
Toll gates for pathogen selection: two classes of innate immune receptors discriminate between different microbial pathogens to mediate host deference by mammalian macrophages.BusinessRichard J. Ulevitch
Transgenic avidin maize is resistant to storage insect pests.BusinessKarl J. Kramer, Thomas D. Morgan, James E. Throne, Floyd E. Dowell, Michele Bailey, John A. Howard
Transgenic commensals as mucosal protectants.Business 
Transgenic plants as factories for biopharmaceuticals.BusinessGlynis et al Giddings
Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogens.BusinessMilan Osusky, Guoqing Zhou, Lubica Osuska, Robert E. Hancock, William W. Kay, Santosh Misra
Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogens.BusinessMilan et al Osusky
Trehalose expression confers desiccation tolerance on human cells.(Brief Article)Business 
Two patent disputes settled.Business 
Universal DNA array detection of small insertions and deletions in BRCA1 and BRCA2.BusinessReyna Favis, Joseph P. Day, Norman P. Gerry, Catherine Phelan, Steven Narod, Francis Barany
Unload the Centrifuge: biospace.com.(Brief Article)Business 
US House biotech report.Business 
Using an AraC-based three-hybrid system to detect biocatalysts in vivo.BusinessSteven M. Firestine, Frank Salinas, Andrew E. Nixon, Stephen J. Baker, Stephen J. Benkovic
US public opinion divided over biotechnology?BusinessSusanna Hornig Priest
Vaccinia's interactions.Business 
Viral vectors do the DNA shuffle.(Analysis)BusinessAtsuhi Miyanohara, Theodore Friedmann
Vitreous cryopreservation maintains the function of vascular grafts.BusinessC. Song et al Ying
Wavelength-shifting molecular beacons.BusinessSanjay et al Tyagi
When the Human Genome Jproject and State Street collide.BusinessScott D. Locke, David A. Kalow
Who's your neighbor? New computational approaches for functional genomics?BusinessEugene V. Koonin, Michael Y. Galperin
Xenotransplantation of transgenic pig olfactory ensheathing cells promotes axonal regeneration in rat spinal cord.BusinessToshio et al Imaizumi
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