Nature Medicine 2006 - Abstracts

Nature Medicine 2006
TitleSubjectAuthors
A(beta) star: A light onto synaptic dysfunction?HealthSangram S. Sisodia, Seong-Hun Kim, Ya-Ping Tang
A channel to neurodegeneration.(parkinson disease)HealthDanny G. Winder, Ariel Y. Deutch
A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy.HealthMasaaki Hayashi, Kyoko Imanaka-Yoshida, Toshimichi Yoshida, Malcolm Wood, Colleen Fearns, Revati J. Tatake, Jiing-Dwan Lee
Activate protein C inhibits tissue plasminogen activator-induced brain hemorrhage.HealthJohn H. Griffin, Tong Cheng, Jose A. Fernandez, Berislav V. Zlokovic, Rashid Deane, Zhang Li, Dong Liu, Zhenhua Wu, Anthony L. Petraglia, Meenakshisundaram Thiyagarajan, Zhihui Zhong, Sanjay B. Maggirwar, Barbara LaRue, Michael Chopp
Activation of [[beta].sub.2]-adrenergic receptor stimulates [gamma]-secretase activity and accelerates amyloid plaque formation.HealthGang Pei, Guobin Bao, Yanxiang Ni, Xiaohui Zhao, Lin Zou, Lin Teng, Zhu Wang, Min Song, Jiaxiang Xiong, Yun Bai
Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogenetic hematopoietic stem cell transplantation.HealthJuan Carlos Zuniga-Pflucker, Glen Heller, Eric G. Pamer, Johannes L. Zakrzewski, Adam A. Kochman, Sydney X. Lu, Theis H. Terwey, Theo D. Kim, Vanessa M. Hubbard, Stephanie J. Muriglan, David Suh, Odette M. Smith, Jeremy Grubin, Neel Patel, Andrew Chow, Javier Cabrera-Perez, Radhika Radhakrishnan, Adi Diab, Miguel-Angel Perales, Gabrielle Rizzuto, Ewa Menet, Onder Alpdogan, Marcel R.M. van den Brink
Alice Dautry.HealthDeclan Butler
ALS: Life and death in a bad neighborhood.(amyotrophic lateral sclerosis)HealthPeter N. Monk, Pamela Shaw
Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia.(N-methyl-D-aspartate)HealthWade H. Berrettini, Chang-Gyu Hahn, Hoau-Yan Wang, Dan-Sung Cho, Konrad Talbot, Raquel E. Gur, Kalindi Bakshi, Joshua Kamins, Karin E. Borgmann-Winter, Steven J. Siegel, Robert J. Gallop, Steven E. Arnold
Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia.(N-methyl-D-aspartate)HealthWade H. Berrettini, Chang-Gyu Hahn, Hoau-Yan Wang, Dan-Sung Cho, Konrad Talbot, Raquel E. Gur, Kalindi Bakshi, Joshua Kamins, Karin E. Borgmann-Winter, Robert J. Gallop, Steven E. Arnold
Alzheimer disease.HealthB. Brett Finlay, Inna Sekirov
Alzheimer disease: Presenilin springs a leak.HealthSam Gandy, Mark K. Doeven, Bert Poolman
Alzheimer disease: Progress or profit?HealthClaire Mount, Christian Downton
Alzheimer disease research in Japan: Public funding.HealthTakeshi Iwatsubo, Ichiro Kanazawa, Yasuo Ihara
Alzheimer protease hitches a ride.HealthMichael S. Wolfe
Alzheimer's APP mangles mitochondria.HealthM. Flint Beal, Michael T. Lin
A male contraceptive targeting germ cell adhesion.HealthDolores D. Mruk, Ching-Hang Wong, Bruno Silvestrini, C. Yan Cheng
Amyloid at the blood vessel wall.HealthJohn Hardy, Karen Cullen
Angiogenesis and inflammation face off.HealthMichel Aurrand-Lions, Beat A. Imhof
Angiogenesis as a therapeutic target.HealthNapoleone Ferrara, Robert S. Kerbel
Angiogenesis in life, disease and medicine.HealthPeter Carmeliet
Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation.HealthGavin Thurston, Peter Vajkoczy, Ulrike Fiedler, Yvonne Reiss, Marion Scharpfenecker, Verena Grunow, Stefanie Koidl, Nicholas W Gale, Martin Witzenrath, Simone Rosseau, Norbert Suttorp, Astrid Sobke, Matthias Herrmann, Klaus T. Preissner, Hellmut G. Augustin
Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells.HealthHarvey F. Lodish, Cheng Cheng Zhang, Megan Kaba, Guangtao Ge, Kathleen Xie, Wei Tong, Christohpher Hug
An important difference.(research of genetic mutations)HealthPatrick Goymer
A novel dendritic cell subset involved in tumor immunosurveillance.HealthGuido Kroemer, Hideo Yagita, Graca Raposo, Caroline Flament, Thomas Tursz, Laurence Zitvogel, Thierry Poynard, David Klatzmann, Julien Taieb, Nathalie Chaput, Cedric Menard, Lionel Apetoh, Evelyn Ullrich, Mathieu Bonmort, Marie Pequignot, Noelie Casares, Magali Terme, Paule Opolon, Yann Lecluse, Didier Metivier, Elena Tomasello, Eric Vivier, Francois Ghiringhelli, Francois Martin, Bernard Ryffel
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.HealthNathaniel M. Weathington, Anneke H. van Houwelingen, Brett D. Noerager, Patricia L. Jackson, Aletta D. Kraneveld, F. Shawn Galin, Gert Folkerts, Frans P. Nijkamp, J. Edwin Blalock
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells.HealthAnthony J. Demetris, Ju-Seog Lee, Diego F. Calvisi, Frederik Nevens, Jeonghoon Heo, Arsen Mikaelyan, Tania Roskams, Louis Libbrecht, Lewis R. Roberts, Snorri S. Throgirsson, In-Sun Chu, Pal Kaposi-Novak, Zongtang Sun
Anti-inflammatory actions of lipoxin A4 and asprin-triggered lipoxin are SOCS-2 dependent.HealthCharles N. Serhan, Fabiana S. Machado, James E. Johndrow, Lisia Esper, Alexandra Dias, Andre Bafica, Julio Aliberti
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.HealthAnthony P. Davenport, Janet J. Maguire, Trevor D. Littlewood, Murray C.H. Clarke, Nichola Figg, Martin Goddard, Martin R. Bennett
A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines.HealthQuentin J. Sattentau, Amin Moghaddam, Wieslawa Olszewska, Belinda Wang, John S. Tregoning, Rebecca Helson, Peter J.M. Openshaw
Approaches to microRNA discovery.HealthEdwin Cuppen, Eugene Berezikov, Ronald H A Plasterk
A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis.HealthMing Yan, Janet D. Rowley, Yang Wang, Luke F. Peterson, Eiki Kanbe, Anita Boyapati, Yuqin Miao, I-Ming Chen, Zixing Chen, Cheryl L. Willman, Dong-Er Zhang
Are all fats created equal?(Visafin used to treat type 2 diabetes)HealthStephen R. Bloom, Kevin G. Murphy
ARNT misbehavin' in diabetic beta cells.(arylhydrocarbon nuclear receptor translocator)HealthMichael P. Czech
A role for the scaffolding adapter GAB2 in breast cancer.HealthHaihua Gu, Benjamin G. Neel, Andrea Richardson, Mohamed Bentires-Alj, Susana G. Gil, Richard Chan, Zhigang C. Wang, Yongping Wang, Naoko Imanaka, Lyndsay N. Harris
A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord.HealthHideyuki Okano, Zhigang He, Yoshio Goshima, Masahiko Taniguchi, Masaya Nakamura, Yoshiaki Toyama, Shinjiro Kaneko, Akio Iwanami, Akiyoshi Kishino, Kaoru Kikuchi, Shinsuke Shibata, Hirotaka J. Okano, Takeshi Ikegami, Ayako Moriya, Osamu Konishi, Chikao Nakayama, Kazuo Kumagai, Toru Kimura, Yasufumi Sato, Mamoru Ito
A sensitive and high-throughput assay to detect low-abundance proteins in serum.HealthHongtao Zhang, Xin Cheng, Mark Richter, Mark I. Greene
A shot of fear.(side effects of vaccination on children health)HealthVirginia Hughes
A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees.(hepatitis C virus )HealthAntonella Folgori, Stefania Capone, Lionello Ruggeri, Annalisa Meola, Elisabetta Sporeno, Bruno Bruni Ercole, Monica Pezzanera, Rosalba Tafi, Mirko Arcuri, Elena Fattori, Armin Lahm, Alesandra Luzzago, Alessandra Vitelli, Stefano Colloca, Riccardo Cortese, Alfredo Nicosia
A transgenic triple scores a home run.HealthGreg Cole
Australians back bacterial theory for bowel disease.HealthCarina Dennis
Autoimmunity and tumor immunity induced by immune responses to mutations in self.HealthAlan N. Houghton, Andrea T. Hooper, Manuel E. Engelhorn, Jose A. Guevara-Patino, Gabriele Noffz, Olivia Lou, jason S. Gold, Barry J. Kappel
Bad medicine.HealthNatasha Bolognesi
Bad seeds.(rous strain of avian sarcoma research)HealthArianne Heinrichs
Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.HealthJonathan R.T. Lakey, Mark Mercola, Ergeng Hao, Bjorn Tyrberg, Pamela Itkin-Ansari, Ifat Geron, Edward Z. Monosov, Maria Barcova, Fred Levine
Bone loss goes beyond estrogen.HealthT. John Martin, Dana Gaddy
Breast cancer research neglects non-Jewish groups, experts charge.HealthBrandon Keim
Budget cuts put children's health study on chopping block.HealthBrian Vastag
Bug killers.(phage therapy)HealthThomas Hausler
Canalization of development by microRNAs.HealthEran Hornstein, Naom Shomron
Cancer genes and the pathways they control.HealthKenneth W. Kinzler, Bert Vogelstein
Cancer gets the Chk'ered flag.HealthLiu Cao, Toren Finkel
Cannabinoids hurt, heal in cirrhosis.HealthBin Gao, Sandor Batkai, George Kunos, Douglas Osei-Hyiaman
Can the immune system fight Alzheimer disease?HealthJohn H. Growdon, Bradley T. Hyman
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.HealthBrian Walters, Joseph Alroy, Richard A. Van Etten, Anthony Rosenzweig, Robert N. Salomon, Thomas Force, Risto Kerkela, Luanda Grazette, Rinat Yacobi, Cezar Iliescu, Richard Patten, Cara Beahm, Sergei Shevtsov, Stephanie Pesant, Fred J. Clubb, Jean-Bernard Durand
Carminerin contributes to chrondrocyte calcification during endochondral ossification.HealthTakashi Yamada, Shigeaki Kato, Yosuke Kawasaki, Hiroshi Kawaguchi, Kimihiro Yoshimura, Kozo Nakamura, Hirotaka Kawano, Kazuto Hoshi, Satoru Kamekura, Ung-il Chung, Toshiyuki Ikeda, Toru Fukuda, Yu Koshizuka, Taku Saito, Yoshiaki Azuma, Shiro Ikegawa
CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis.HealthCatherine Ledent, Fatima Teixeira-Clerc, Boris Julien, Pascale Grenard, Vanessa Deveaux, Liying Li, Valerie Serriere-Lanneau, Ariane Mallat, Sophie Lotersztajn
Channeling pain.(treating pain)HealthArdem Patapoutian, Lindsey Macpherson
Chemotherapy and the war on cancer.HealthBruce A. Chabner, Thomas G. Roberts Jr.
Cholesterol glucosylation promotes immune evasion by Helicobacter pylori.HealthFlorian Winau, Ernst Heinz, Ulrich Zahringer, Thomas F. Meyer, Christian Wunder, Yuri Churin, Dirk Warnecke, Michael Vieth, Buko Lindner, Hans-Joachim Mollenkopf
Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis.HealthYasunori Okada, Satoshi Ogawa, Shinsuke Yuasa, Keiichi Fukuda, Makio Mukai, Chisa Shukunami, Masatoyo Yoshioka, Keisuke Matsumura, Kensuke Kimura, Takayuki Shiomi, Naritaka Kimura, Hankei Shin, Ryohei Yozu, Masataka Sata, Yuji Hiraki
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma.HealthDavid M. Gershenson, Gabriel Lopez-Berestein, Anil K. Sood, Robert L. Coleman, Susan K. Lutgendorf, Yang Li, Premal H. Thaker, Liz Y Han, Aparna A. Kamat, Jesusa M. Arevalo, Rie Takahashi, Chunhua Lu, Nicholas B. Jennings, Guillermo Armaiz-Pena, James A. Bankson, Murali Ravoori, William M. Merritt, Yvonne G Lin, Lingegowda S. Mangala, Tae Jin Kim, Charles N. Landen, Edward Felix, Angela M. Sanguino, Robert A. Newman, Mary Lloyd, Vikas Kundra, Steven W. Cole
Clinical trials for antipsychotic drugs: Design conventions, dilemmas and innovations.(Clinical report)HealthJeffrey A. Lieberman, Robert M. Hamer, Scott T. Stroup, Wayne M. Alves
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.HealthMatthew J. Watt, Mark A. Febbraio, David Carling, Walter G. Thomas, Matthias Ernst, Nicolas Dzamko, Stefan Rose-John, Bruce E. Kemp, Gregory R. Steinberg
Coexpression of virulence and fosfomycin susceptibility in Listeria: Molecular basis of an antimicrobial in vitro-in vivo paradox.HealthMartin Wagner, Mariela Scortti, Jose A. Vazquez-Boland, Lizeth Lacharme-Lora, Patrizia Losito, Isabel Chico-Calero
Combating diabetes and obesity in Japan.HealthTakashi Kadowaki, Yoshio Yazaki
Comprehensive volumetric optical microscopy in vivo.HealthNorman S. Nishioka, Seok H Yun, Guillermo J. Tearney, Benjamin J. Vakoc, Milen Shishkov, Wang Y Oh, Adrien E. Desjardins, Melissa J. Suter, Raymond C. Chan, John A. Evans, Ik-Kyung Jang, Johannes F. de Boer, Brett E. Bouma
Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.HealthHideyuki Okano, Masaya Nakamura, Seiji Okada, Hiroyuki Katoh, Tamaki Miyao, Takuya Simazaki, Ken Ishii, Junichi Yamane, Yoshimura Akihiko, Yukihide Iwamoto, Yoshiaki Toyama
Connexin37 protects against atherosclerosis by regulating monocyte adhesion.HealthCindy W. Wong, Thomas Christen, Isabelle Roth, Christos E. Chadjichristos, Jean-Paul Derouette, Bernard F. Foglia, Marc Chanson, Daniel A. Goodenough, Brenda R. Kwak
Controlling angiogenesis in heart valves.HealthRaghu Kalluri, Elisabeth Zeisberg
Controlling immune response may cut bird flu death rate.HealthHelen Pearson
Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.HealthGiuliana Ferrari, Fulvio Mavilio, Michele De Luca, Alberto Giannetti, Stefano Ferrari, Graziella Pellegrini, Francesca Di Nunzio, Enzo Di Iorio, Alessandra Recchia, Giulietta Maruggi, Elena Provasi, Chiara Bonini, Sergio Capurro, Andrea Conti, Cristina Magnoni
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.HealthCynthia Dunbar, Adrian J. Thrasher, Nancy A. Jenkins, Neal G. Copeland, Dieter Hoelzer, Manfred Schmidt, Yang Du, Manuel Grez, Stefan Stein, Marion G. Ott, Ulrike Koehl, Sonja Naundorf, Ingo Pilz, Ursula Luthi, Reinhard Serger, Hanno Glimm, Andrea Brinkmann, Moustapha Hassan, Kerstin Schwarzwaelder, Klaus Kuhlcke, Annette Deichmann, Andrea Schilz, Marlene Fischer, Ulrich Siler, Hana Kunkel, Claudia Ball, Christof von Kalle
Cracking the fungal armor.HealthTobias M. Hohl, Eric G. Pamer
Cross-dressing T cells go wild.HealthLudvig M. Sollid, John T. Vaage
Cutting and pasting chromosomes.(philadelphia chromosome)HealthKristine Novak
Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.HealthCarol Ward, Adriano G. Rossi, Deborah A. Sawatzky, Annemieke Walker, Tara A. Sheldrake, Nicola A. Riley, Alison Caldicott, Magdalena Martinez-Losa, Trevor R. Walker, Rodger Duffin, Mohini Gray, Elvira Crescenzi, Morag C. Martin, Hugh J. Brady, John S. Savill, Ian Dransfield, Christopher Haslett
Cyclohexanehexol inhibitors of A(beta) aggregation prevent and reverse Alzheimer phenotype in a mouse model.HealthJoAnne McLaurin, Howard T.J. Mount, Paul E. Fraser, David Westaway, Fusheng Chen, Meredith E. Kierstead, Mary E. Brown, Cheryl A. Hawkes, Mark H.L. Lambermon, Amie L. Phinney, Audrey A. Darabie, Julian E. Cousins, Janet E. French, Melissa F. Lan, Sydney S.N. Wong, Peter George-Hyslop St.
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4(super +) hemangiocytes.HealthZena Werb, Ronald G. Crystal, David Lyden, Koichi Hattori, Beate Heissig, Neil R. Hackett, Shahin Rafii, Yan Wu, Daniel J. Hicklin, Fan Zhang, Scott T. Avecilla, Koji Shido, David K. Jin, Zhenping Zhu, Hans-Georg Kopp, Isabelle Petit, Sergey V. Shmelkov, Lauren M. Young, Andrea T. Hooper, Hideki Amano, Ashley Dunn, Hassan Salari
Dealing with disclosure.(scientific ethics)Health 
Death defying.HealthNicola McCarthy
Decidual NK cells regulate key developmental processes at the human fetal-maternal interface.HealthSimcha Yagel, Debra Goldman-Wohl, Caryn Greenfield, Eli Keshet, Inbal Avraham, Jacob Hanna, Yaron Hamani, Shira Natanson-Yaron, Diana Prus, Leonor Cohen-Daniel, Tal I. Arnon, Irit Manaster, Roi Gazit, Vladimir Yutkin, Daniel Benharroch, Ofer Mandelboim
Decoy receptor springs to life and eases fibrosis.HealthThomas T. MacDonald
Defending the epithelium.HealthMichael Zasloff
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance.HealthLeo A.B. Joosten, Charles A. Dinarello, Shizuo Akira, Robert H. Eckel, Mihai G. Netea, Eli Lewis, Dalan R. Jensen, Peter J. Voshol, Bart Jan Kullberg, Cees J. Tack, Han Van Krieken, Soo-Hyun Kim, Anton F. Stalenhoef, Fons A. Van de Loo, Verschueren Ineke, Leslie Pulawa, Wim Van den Berg, Jos W.M. Van der Meer
Design and use of conditional MHC class I ligands.HealthJohn B.A.G. Haanen, Ton N.M. Schumacher, Guus F. Rimmelzwaan, Mireille Toebes, Miriam Coccoris, Adriaan Bins, Boris Rodenko, Raquel Gomez, Nella J. Nieuwkoop, Willeke van de Kasteele, Huib Ovaa
Developmental programming of the hypothalamus: A matter of fat.(metabolic disorders)HealthTamas L. Horvath, Jens C. Bruning
Diabetes and obesity: The twin epidemics.HealthSimon Smyth, Andrew Heron
Diabetes research investment in the European Union.HealthPhilippe A. Halban, Ele Ferrannini, Jorn Nerup
Did a muscle fuel gauge conquer the brain?(adenosine monophosphate)HealthAlessandro Pocai, Evan David Muse, Luciano Rosetti
Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse.HealthWen Jiang, Lei Li, Yun Zhang, Shao-Pin Ji, Jamie Van Cleemput, Mingxia Liao, Qi Wan, Jon R. Backstrom, Xia Zhang
Dynamic modeling of imatinib-treated chronic myeloid leukemia: Functional insights and clinical implications.HealthMatthias Horn, Markus Loeffler, Andreas Hochhaus, Ingo Roeder, Ingmar Glauche, Martin C. Mueller
E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis.HealthCho-Rok Jung, Kyung-Sun Hwang, Jinsang Yoo, Won-Kyung Cho, Jin-Man Kim, Woo Ho Kim, Dong-Soo Im
Effective gene therapy with nonintegrating lentiviral vectors.HealthChristine Kinnon, Adrian J. Thrasher, John R. Heckenlively, Manfred Schmidt, Rafael J. Yanez-Munoz, Kamaljit S. Balaggan, Angus MacNeil, Steven J. Howe, Alexander J. Smith, Prateek Buch, Robert E. MacLaren, Patrick N. Anderson, Susie E. Barker, Yanai Duran, Cynthia Bartholomae, Christof Von Kalle, Robin R. Ali
Embryogenesis meets tumorigenesis.HealthJohn T. Lee, Meenhard Herlyn
Embryonic and tumorigenic pathways converge via nodal signaling: Role in melanoma aggressiveness.HealthMary J.C. Hendrix, Jacek Topczewski, Jolanta M. Topczewska, Brian J. Nickoloff, Lynne-Marie Postovit, Naira V. Margaryan, Anthony Sam, Angela R. Hess, William W. Wheaton
Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer.HealthLuigi Naldini, Mary Anna Venneri, Brian D. Brown, Anna Zingale, Lucia Sergi Sergi
Endothelial cells and VEGF in vascular development.(vascular endothelial growth factor )HealthJanet Rossant, Leigh Coultas, Kallayanee Chawengsaksophak
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts.HealthThomas Eschenhagen, Wolfram-Hubertus Zimmermann, Uwe Nixdorff, Stefan Dhein, Ivan Melnychenko, Andreas Hess, Alexander Schwoerer, Gerald Wasmeier, Lubos Budinsky, Heimo Ehmke, Michael Didie, Kay Brune, Hiroshi Naito, Bjela Michaelis
Environmental awareness.(experiments on tumour cells )HealthAlison Schuldt
Epidemiologic and economic consequences of the global epidemics of obesity and diabetes.HealthKelly D. Brownell, Derek Yach, David Stuckler
Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells.HealthJosef M. Penninger, Thomas Schwarz, Karin Loser, Annette Mehling, Stefanie Loeser, Jenny Apelt, Annegret Kuhn, Stephan Grabbe, Stefan Beissert
Eradication of established tumors in mice by a combination antibody-based therapy.HealthKazuyoshi Takeda, Mark J. Smyth, Hideo Yagita, Ko Okumura, Robert S. Mittler, Tomoyasu Uno, Yuko Kojima, Hirohisa Yoshizawa, Hisaya Akiba, Fumitake Gejyo
ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli.HealthAnura Rambukkana, Nikos Tapinos, Makoto Ohnishi
European Union research policy and funding for Alzheimer disease.HealthPhilippe Cupers, Jurgan Sautter, Alain Vanvossel
Exogenous control of mammalian gene expression via modulation of translational termination.HealthRichard C. Mulligan, George J. Murphy, Gustavo Mostoslavski, Darrell N. Kotton
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis.HealthSebastian Schuchmann, Dietmar Schmitz, Claudio Rivera, Sampsa Vanhatalo, Benedikt Salmen, Ken Mackie, Sampsa T. Sipila, Juha Viopio, Kai Kaila
Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.HealthPatrick De Baetselier, Etienne Pays, Serge Muyldermans, Toya Nath Baral, Stefan Magez, Benoit Stijlemans, Katja Conrath, Benoit Vanhollebeke
Fast predators or fast food, the fit still survive.HealthClay F. Semenkovich, Carlos Bernal-Mizrachi
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia.(Clinical report)HealthTran Tinh Hien, Jeremy Farrar, Bach Van Cam, Phan Tu Qui, Vo Minh Hien, Tran Tan Thanh, Do Quang Ha, Nguyen Van Vinh Chau, Yi Guan, Gavin J.D. Smith, Menno D de Jong, Cameron P. Simmons, Tran Nguyen Bich Chau, Dang Minh Hoang, Truong Huu Khanh, Vo Cong Dong, Malik J.S. Peiris, Nguyen Tran Chinh
Fat fuels insulin resistance through toll-like receptors.HealthMatthias Tschop, George Thomas
Feeding signals and drugs meet in the midbrain.HealthRichard Simerly
Fighting infections with vitamin D.HealthMichael Zasloff
Fluoroquinolone-modifying enzyme: A new adaptation of a common aminoglycoside acetyltransferase.HealthDavid C. Hooper, George A. Jacoby, Ari Robicsek, Chi Hye Park, Jacob Strahilevitz, Karen Bush, Mark Macielag, Darren Abbanat
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake.HealthGregory S. Barsh, Domenico Accili, Luciano Rossetti, Tadahiro Kitamura, Yun Feng, Yukari Ido Kitamura, Streamson C. Chua, Allison W. Xu
Foxa2, a novel transcriptional regulator of insulin sensitivity.HealthPere Puigsercer, Joseph T. Rodgues
From angiogenesis to neuropathology.HealthDavid A. Greenberg, Kunlin Jin
From hens to eternity.HealthEmma Greenwood
From obscurity to the clinic.HealthAlex Eccleston
Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors.HealthG.C. Minetti, C. Colussi, R. Adami, C. Serra, C. Mozzetta, V. Parente, S. Fortuni, S. Straino, M. Sampaolesi, Di M. Padova, B. Illi, P. Gallinari, C. Steinkuhler, M.C. Capogrossi, V. Sartorelli, R. Bottinelli, C. Gaetano, P.L. Puri
Functional engraftment of human ES cell-derived dopaminergic neuron enriched by coculture with telomerase-immortalized midbrain astrocytes.(embryonic stem cell culture)HealthSteven A. Goldman, M. Flint Beal, Neeta S. Roy, Carine Cleren, Shashi K. Singh, Lichuan Yang
Functions of microRNAs and related small RNAs in plants.HealthHerve Vaucheret, Allison C Mallory
Gamma secretase-medicated Notch signaling worsens brain damage and functional outcome in ischemic stroke.HealthLucio Miele, Mark P. Mattson, Thiruma V. Arumugam, Sic L. Chan, Dong-Gyu Jo, Gokhan Yilmaz, Sung-Chun Tang, Aiwu Cheng, Marc Gleichmann, Eitan Okun, Vishwa D. Dixit, Srinivasulu Chigurupati, Mohamed R. Mughal, Xin Ouyang, Tim Magnus, Suresh Poosala, D. Neal Granger
G-CSF induces E-selectin ligand expression on human myeloid cells.(granulocyte colony-stimulating factor)HealthCharles P. Lin, Nilesh M. Dagia, Samah Z. Gadhoum, Christine A. Knoblauch, Joel A. Spencer, Parisa Zamiri, Robert Sackstein
Generation of C5a in the absence of C3: a new complement activation pathway.HealthJohn G. Younger, Rick A. Wetsel, Peter A. Ward, Markus Huber-Lang, J. Vidya Sarma, Firas S. Zetoune, Daniel Rittirsch, Thomas A. Neff, Stephanie R. McGuire, John D. Lambris, Roscoe L. Warner, Michael A. Flierl, Laszlo M. Hoesel, Florian Gebhard, Scott M. Drouin
Gene therapy finds welcoming environment in China.HealthHepeng Jia
Genetic model of selective COX2 inhibition reveals novel heterodimer signaling.HealthGarret A. FitzGerald, Robert L. Campbell, Colin D. Funk, Ying Yu, Jinjin Fan, Xin-Sheng Chen, Dairong Wang, Andres J. Klein-Szanto
Genomic signatures to guide the use of chemotherapeutics.HealthJeffrey Marks, Andrew Berchuck, Joseph R. Nevins, Michael J. Kelley, Gina Chan, Anil Potti, David Harpole, Holly K. Dressman, Andrea Bild, Richard F. Riedel, Robyn Sayer, Janiel Cragun, Hope Cottrill, Rebecca Petersen, Geoffrey S. Ginsbury, Phillip Febbo, Jonathan Lancaster
Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation.HealthJennifer J. Trowbridge, Anargyros Xenocostas, Moon T. Randall, Mickie Bhatia
Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice.HealthDavid J. Lockhart, Inder M. Verma, Carrolee Barlow, Eric E. Schadt, Iiris Hovatta, Richard S. Tennant, Robert Helton, Oded Singer, Jeffrey M. Redwine, Robert A. Marr, Julie A. Ellison
Growing pains.Health 
GTP cyclohydrolase and tetrahydrobioterin regulate pain sensitivity and persistence.HealthHelmut Schmidt, Andrew Allchorne, Clifford J. Woolf, David Goldman, Mitchell B. Max, Steven J. Atlas, Irmgard Tegeder, Michael Costigan, Robert S. Griffin, Andrea Abele, Inna Belfer, Corina Ehnert, Jemiel Nejim, Claudiu Marian, Joachim Scholz, Tianxia Wu, Luda Diatchenko, Alexander M. Binshtok, Jan Adolph, Swetha Sama, William A. Carlezon, Aram Parsegian, Jorn Lotsch, Roger B. Fillingim, William Maixner, Gerd Geisslinger
Gut microbes out of control in HIV infection.HealthBarton F. Haynes
HDAC7 supports vascular integrity.(histone deacetylase 7)HealthJoseph M. Miano, Bradford C. Berk
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid.HealthJames M. Wilson, Luk H. Vandenberghe, Lili Wang, Suryanarayan Somanathan, Yan Zhi, Joanita Figueredo, Roberto Calcedo, Julio Sanmiguel, Ravi A. Desai, Christopher S. Chen, Julie Johnston, Rebecca L. Grant, Guangping Gao
Histidine button engineered into cardiac troponin I protects the ischemic and failing heart.HealthJoseph M. Metzger, Soichiro Yasuda, Sherlene M. Day, Margaret V. Westfall, Ekaterina V. Fomicheva, Kirsten Hoyer, Nathan C. La Cross, Louis G. D'Alecy, Joanne S. Ingwall
How an anomalous finding led to a new system of psychotherapy.HealthAaron T. Beck
How diabetes went to our heads.(insulin resistance and rise in glucose leads to diabetes)HealthRandy J. Seeley, Matthias Tschop
Human amyloid-(beta) synthesis and clearance rates as measured in cerebrospinal fluid in vivo.HealthKevin E. Yarasheski, John C. Morris, David M. Holtzman, Randall J. Bateman, Ling Y. Munsell, Robert Swarm
Human and microbe: United we stand.HealthB. Brett Finlay, Inna Sekirov
Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.HealthAshley T. Haase, Jacob D. Estes, J. Victor Garcia, Michael W. Melkus, Angela Padgett-Thomas, Joel Gatlin, Paul W. Denton, Florence A. Othieno, Anja K. Wege
Human sebaceous tumors harbor inactivating mutations in LEF1.HealthStephen Lyle, Fiona M. Watt, Hikaru Takeda, Alexander J.F. Lazar, Christos C. Zouboulis, Ian Smyth
Human tissue-engineered blood vessels for adult arterial revascularization.HealthThomas N. Wight, Robert C. Robbins, Nicolas L'Heureux, Nathalie Dusserre, Gerhardt Konig, Braden Victor, Paul Keire, Nicolas A.F. Chronos, Andrew E. Kyles, Clare R. Gregory, Grant Hoyt, Todd N. McAllister
Hyperoxia causes angiopoietin Z-mediated acute lung injury and necrotic cell death.HealthLorraine B. Ware, Michael A. Matthay, Vineet Bhandari, Robert J. Homer, Jack A. Elias, Zhou Zhu, Patty J. Lee, Choo-Wing Rayman, Chun G. Lee, Jonathan H. Nedrelow, Geoffrey L. Chupp, Xucher Zhang, Anke Geick, Antonin R. de Fougerolles
Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency.HealthYusuke Maeda, Taroh Kinoshita, Peter Hillmen, Stephen Richards, Antonio M. Almeida, Yoshiko Murakami, D. Mark Layton, Gabrielle S. Sellick, Scott Patterson, Ioannis Kotsianidis, Luigina Mollica, Dorothy H. Crawford, Alastair Baker, Michael Ferguson, Irene Roberts, Richard Houlston, Anastasios Karadimitris
Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior.HealthStuart A. Lipton, Sarah F. Leibowitz, Shi-Hua Li, Guoqing Sheng, Guo-qing Chang, John Y. Lin, Zhao-Xue Yu, Zhi-Hui Fang, Juan Rong, Gang Tong, Xiao-Jiang Li
Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer.(target of rapamycin)HealthCharles L. Sawyers, Johannes Czernin, Derek S. Welsbie, Ingo K. Mellinghoff, Emily Chan, George V. Thomas, Tran Chris, Barbara Fueger
Hypoxia pathway linked to kidney failure.HealthGregg L. Semenza
Identification of a hormonal basis for gall bladder filling.HealthJames A. Richardson, H. Eric Xu, David J. Mangelsdorf, Steven A. Kliewer, Angie L. Bookout, Antonio Moschetta, Robert D. Gerard, Kelly Suino-Powell, Mihwa Choi, Li Peng, Michihisa Umetani, Sam R. Holmstrom
IL-13 signaling through the IL-13alpha(sub 2) receptor is involved in induction of TGF-beta(sub 1) production and fibrosis.HealthWarren Strober, Stefan Fichtner-Feigi, Raj Kawakami, Raj K. Puri, Atsushi Kitani
Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice.HealthShigeaki Kato, Takahiro Matsumoto, Hirotake Masuda, Kimihiro Yoshimura, Koichi Kawamura, Kimiko Yamamoto, Takaakki Sokabe, Shibata Masahiro, Norihiko Ohura, Toru Fukuda, Takashi Sato, Keisuke Sekine, Masashi Isshiki, Toshiro Fujita, Mikio Kobayashi, Akira Kamiya, Joji Ando
Improving metabolism by increasing energy expenditure.HealthJohan Auwrex
Inbred Israeli families aid research on rare diseases.HealthLuba Vikhanski
Indirect but just as effective.HealthAngela K. Eggleston
Induction of leptin resistance through direct interaction of C-reactive protein with leptin.HealthDavid E. Kelley, Ji Li, Ke Chen, Alessandro Bisello, Alexander J. Szalai, Fanghong Li, Allan Z. Zhao, Miriam Freidman-Einat, Hongbo Cai, Gregory A. Skibinski, Steven Strom, Mark A. McCrory
Inflammation in Alzheimer disease: driving force, bystander or beneficial response?HealthTony Wyss-Coray
Inserting optimism into gene therapy.HealthLuigi Naldini
Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression.(duffy antigen receptor for chemokines)HealthYing Wang, Sucharita Bandyopadhyay, Rui Zhan, Asok Chaudhuri, Misako Watabe, Sudha K. Pai, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Yukio Takano, Ken Saito, Mary E. Pauza, Sunao Hayashi, Sonia Mohinta, Tomoyuki Mashimo, Megumi Iiisumi, Eiji Furuta, Kounosuke Watabe
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity.HealthLewis L. Lanier, Thomas W. Dubensky, Drew M. Pardoll, Camie W. Chan, Emily Crafton, Hong-Ni Fan, James Flook, Kiyoshi Yoshimura, Mario Skarica, Dirk Brockstedt, Monique F. Stins, Franck Housseau
Interleukin-10 determines viral clearance or persistence in vivo.HealthMichael B.A. Oldstone, David G. Brooks, Luc Teyton, Matthew J. Trifilo, Kurt H. Edelmann, Dorain B. McGavern
Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors.HealthMichael P. Cooke, Philip D. Greenberg, Claes Ohlen, Ryan M. Teague, Blythe D. Sather, Jilian A. Sacks, Maria Z. Huang, Michelle Dossett L., Junko Morimoto, Xiaoxio Tan, Susan E. Sutton
Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation.HealthJe-Min Choi, Mi-Hyun Ahn, Wook-Jin Chae, Yung-Gook Jung, Jae-Chul Park, Hyun-Mi Song, Young-Eun Kim, Jung-Ah Shin, Choon-Sik Park, Jung-Won Park, Tae-Kwann Park, Jung-Hoon Lee, Byung-Fhy Seo, Kyun-Do Kim, Eun-Sung Kim, Dong-Ho Lee, Seung-Kyou Lee, Sang-Kyou Lee
Intravenous immunoglobulin ameliorates ITP via activating Fcgamma small letter gamma receptors on dendritic cells.HealthVinayakumar Siragam, Andrew R. Crow, Davor B rinc, Seng Song, John Freedman, Alan H. Lazarus
Intrinsic tumour suppression.Health 
In vivo imaging of islet transplantation.HealthSusan Bonner-Weir, Anna Moore, Natalia V. Ergenov, Zdravka Medarova, Guangping Dai
In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus.HealthHiroyuki Mizuguchi, Hiroyuki Kishimoto, Toru Kojima, Yuichi Watanabe, Shunsuke Kagawa, Toshiya Fujiwara, Uno Futoshi, Fuminori Teraishi, Satoru Kyo, Yuuri Hashimoto, Yasuo Urata, Noriaki Tanaka, Toshiyoshi Fujiwara
Is cancer a disease of self-seeding?HealthJoan Massague, Larry Norton
Is it a DC, is it an NK? No, it's an IKDC.(interferon-producing killer dendritic cell )HealthKen Shortman, Jose A. Villadangos
Islets break off from the mainland.HealthJoel F. Habener, J. Michael Rukstalis
Janet Rowley.(research on abnormal chromosomes in leukemia cells)(Biography)HealthKris Novak
John 'J.J.' Cohen.(Biography)HealthKendall Powell
Keeping the fat off with nesfatin.HealthMartin G. Myers Jr.
Klotho-induced insulin resistance: A blessing in disguise.HealthRoger H. Unger
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia.HealthRudolf Grosschedl, Karl Welte, Martin Stanulla, Gunnar Cario, Michaela Scherr, Julia Skokowa, Murat Uenalan, Axel Schambach, Manuela Germeshausen, Karin Battmer, Cornelia Zeidler, Ulrich Lehmann, Christopher Baum
Lipid microarrays identify key mediators of autoimmune brain inflammation.HealthLawrence Steinman, Jennifer L. Kanter, Sirisha Narayana, Peggy P. Ho, Ingrid Catz, Kenneth G. Warren, raymond A. Sobel, William H. Robinson
Live imaging of lymphatic development in the zebrafish.HealthBrant M. Weinstein, Karina Yaniv, Sumio Isogai, Daniel Castranova, Louis Dye, Jiro Hitomi
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways.HealthGregory S. Korbutt, Ray V. Rajotte, Thomas C. Pearson, Kenneth Cardona, Zvonimir Milas, James Lyon, Jose Cano, Wanhong Jiang, Hameeda Bello-Laborn, Bard Hacquoil, Elizabeth Strobert, Shivaprakash Gangappa, Collin J. Weber, Christian P. Larsen
Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice.HealthPhilip A. Marsden, Susan E. Quaggin, Mie Ding, Shiying Cui, Chengjin Li, Serge Jothy, Volker Haase, Brent M. Steer, Jeffrey Pippin, Stuart Shankland, Maria Pia Rastaldi, Clemens D. Cohen, Matthias Kretzler
Low morale at US agency receives dormant scientists group.(National Institutes of Health)HealthGeorge S. Mack
Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria.HealthIrene Gramaglia, Peter Sobolewski, Diana Meays, Ramiro Contreras, John P. Nolan, John A. Frangos, Marcos Intaglietta, Henri C. van der Heyde
Lymphangiogenesis in development and human disease.HealthKari Alitalo, Tatiana Petrova, Tuomas Tammela
Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants.HealthDontscho Kerjaschki, Nicole Huttary, Ingrid Raab, Heinz Regele, Katalin Bojarski-Nagy, Gregor Bartel, Stefan M. Krober, Hildegard Greinix, Agathe Rosenmaier, Franz Karlhofer, Nikolaous Wick, Peter R. Mazal
Malaria parasites up close.HealthMichael F. Good, Malcolm K. Jones
Memory [T.sub.H]2 cells induce alternatively activated macrophages to mediate protection against nematode parasites.HealthRobert M. Anthony, Joseph F. Urban Jr., Farhang Alem, Hossein A. Hamed, Cristina T. Rozo, Jean-Luc Boucher, Nico Van Rooijen, William C. Gause
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.HealthBruce R. Blazar, Michael M. Lederman, Alan Landay, Steven G. Deeks, Frederick M. Hecht, David A. Price, Jason M. Brenchley, Daniel Altmann, Daniel C. Douek, Jeffrey N. Martin, Louis J. Picker, Olivier Lambotte, Guido Silvestri, Benigno Rodriguez, Timothy W. Schacker, Tedi E. Asher, Srinivas Rao, Zachary Kazzaz, Ethan Bornstein, Leia Teixeira-Johnson
MicroRnas: 'Ribo-regulators' of glucose homeostasis.HealthBenoit R. Gauthier, Claes B. Wollheim
MicroRNA target predictions in animals.HealthNikolaus Rajewsky
Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation.HealthReinhard Fassler, Ingvar Ferby, Rudiger Klein, Axel Ullrich, Wolfgang Sommergruber, Markus Reschke, Oliver Kudlacek, Pjotr Knyazev, Guido Pante, Kerstin Amann, Norbert Kraut
Molecular ablation of ventricular tachycardia after myocardial infarction.HealthJ. Kevin Donahue, Amy D. McDonald, Tetsoo Sasano, Kan Kikuchi
Money matters roil Cleveland Clinic's reputation.HealthBruce Diamond
Monkeypox outbreak diagnostics and implications for vaccine protective effect.HealthErika Hammarlund, Yu Li, Inger K. Damon, Kevin L. Karem, Mary Reynolds, Victoria Olson, Mark Slifka
Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.HealthJeffrey J. Molldrem, Robert A. Krance, Cliona M. Rooney, Ann M. Leen, Doug G. Myers, Uluhan Sili, Helen M. Huls, Heidi Weiss, Kathryn S. Leung, George Carrum, Chung-Che Chang, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, Catherine M. Bollard
Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction.HealthSoichiro Kitamura, Kenji Kangawa, Teruo Okano, Yoshinori Miyahara, Hiroyuki Hao, Shunji Sano, Noritoshi Nagaya, Kozo Ishino, Masaharu Kataoka, Hideyuki Ishida, Bobby Yanagawa, Tatsuya Shimizu, Hidezo Mori, Koichi Tanaka
Move against malaria.Health 
mTOR tells the brain that the body is hungry.(mammalian target of rapamycin)HealthBarbara B. Kahn, Martin G. Myers Jr.
Multiple sclerosis: Putting two and two together.HealthJohn Trowsdale
Mutations in antiquitin in individuals with pyridoxine-dependent seizures.HealthPhilippa B. Mills, Eduard Struys, Cornelis Jakobs, Barbara Plecko, Peter Baxter, Matthias Baumgartner, Michel A.A.P. Willemsen, Heymut Omran, Uta Tacke, Birgit Uhlenberg, Bernhard Weschke, Peter T. Clayton
Mysterious `Morgellons disease' prompts US investigation.HealthEmma Marris
Natural killer T cells and CD[8.sup.plus] T cells are dispensable for T cell-dependent allergic airway inflammation.HealthJyoti Das, Paul Eynott, Ray Jupp, Alfred Bothwell, Luc Van Kaer, Yufang Shi, Gobardhan Das
Natural regulatory T cells control the development of atherosclerosis in mice.HealthRichard A. Flavell, Goran K. Hansson, Regine Merval, Alain Tedgui, Ziad Mallat, Hafid Ait-Oufella, Benoit L. Salomon, Stephane Potteaux, Anna-Karin L. Robertson, Pierre Gourdy, Joffrey Zoll, Bruno Esposito, Jose L. Cohen, Sylvain Fisson, David Klatzmann
Neuronal PTP1B regulates body weight, adiposity and leptin action.HealthBarbara B. Kahn, Gokhan S. Hotamisligil, Benjamin G. Neel, Kendra K. Bence, Mirela Delibegovic, Bingzhong Xue, Cem Z. Gorgun
Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE.HealthYawei Liu, Ingrid Teige, Bryndis Birnir, Shohreh Issazadeh-Navikas
Neurons tame T cells.HealthRobert S. Fujinami
New approaches to antidepressant drug discovery: beyond monoamines.HealthEric J. Nestler, Olivier Berton
New chief brings welcome changes to US cancer agency.(John Niederhuber of National Cancer Institute)HealthTinker Ready
Newly expressed SUR1-regulated NC(sub Ca-ATP) channel mediates cerebral edema after ischemic stroke.HealthSvetlana Ivanova, J. Marc Simard, Ludmila Melnitchenko, Mingkui Chen, Natayya Tsymbalyuk, Kirill V. Tarasov, G. Alexander West, Sergei Bhatta, Volodymyr Gerzanich
New rules propose greater scrutiny for NIH grant recipients.(National Institutes of Health)HealthAlan Dove
NIH research on obesity and type 2 diabetes: Providing the scientific evidence base for actions to improve health.(National Institutes of Health)HealthElizabeth G. Nabel, Allen M. Spiegel
Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates.HealthMartin E. Schwab, Patrick Freund, Eric Schmidlin, Thierry Wannier, Jocelyne Bloch, Anis Mir, Eric M. Rouiller
NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism.HealthPeter Tontonoz, Hironori Waki, Liming Pei, Bhavapriya Vaitheesvaran, Damien C. Wilpitz, Irwin J. Kurland
Observations from a ploughman.(Stephen Paget)HealthHelen Dell
One enzyme inactivates two antibiotics.(flouroquinolone antibiotics used to cure diseases)HealthKeith P. Klugman, Bruce R. Levin
Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing [CD4.sup.}[CD25.sup-][LAP.sup.} T cells.HealthHoward L. Weiner, Hiroki Ishikawa, Hirofumi Ochi, Michal Abraham, Dan Frenkel, Aaiyong Yang, Alexandre S. Basso, Henry Wu, Mei-ling Chen, Roopali Gandhi, Ariel Miller, Ruth Maron
Orexin: A gatekeeper of addiction.HealthDavid Carr, Peter W. Kalivas
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cell.HealthOrit Kollet, Ayelet Dar, Shoham Shivtiel, Alexanderl Kalinkovich, Kfir Lapid, Yejezkel Sztainberg, Melania Tesio, Robert M. Samstein, Polina Goichberg, Asaf Spiegel, Ari Elson
Osteoclasts eat stem cells out of house and home.HealthDavid T. Scadden, Louise E. Purton
Osteoclasts, no longer osteoblast slaves.HealthBrendan F. Boyce, Lianping Xing
Overcoming insulin resistance with CNTF.(Ciliary neurotrophic factor )HealthRexford S. Ahima
Oxygen deprivation provokes melanoma.HealthPaul A. Khavari, Amy E. Adams, Yakov Chudnovsky
Pathogenesis of HIV infection: What the virus spares is as important as what it destroys.HealthWilliam E. Paul, Zvi Grossman, Martin Meier-Schellersheim, Louis J. Picker
Pathophysiologically based treatment interventions in schizophrenia.HealthDavid A. Lewis, Guillermo Gonzalez-Burgos
Pathophysiologically based treatment interventions in schizophrenia.HealthDavid A. Lewis, Guillermo Gonzalez-Burgos
Personalized medicine progresses.HealthJohn N. Haselden, Andrew W. Nicholls
Phosphorylate and conquer.(cancer genetics)HealthEkat Kritikou
Pinpointing plaques with PIB.(Pittsburgh Compound-B)HealthKaj Blennow, Henrik Zetterberg
Plot against pot.HealthKerrie L. Thomas
Precision weapons.(methods developed to prevent against cancer)HealthSimon Frantz
Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis.HealthHarald Mischak, Stephane Decramer, Francois Bouissou, Stefan Wittke, Jean-Loup Bascands, Joost P. Schanstra, Petra Zurbig, Michael Walden
Profiling cancer expression.HealthMagdalena Skipper
Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates.HealthBernhard J. Hering, Pratima Bansal-Pakala, Wei Li, Jeffrey D. Ansite, Masahiko Nakano, Jane Cheng, Kathleen Moran, Henk-Jan Schuurman, Martin Wijkstrom, Melanie L. Graham, Maria Hardstedt, Tor C. Aasheim, Tun Jie, Uwe Christians, Charles D. Mills, David E. Sutherland, Michael P. Murtaugh, Nicole Kirchhof
Prostaglandin E2 EP1 receptors: Downstream effectors of COX-2 neurotoxicity.HealthGang Wang, Costantino Iadecola, Takayuki Kawano, Josef Anrather, Ping Zhou, Laibaik Park, Kelly A. Frys, Alexander Kunz, Sunghee Cho, Marcello Orio
Protein twists and turns in Alzheimer disease.HealthMark P. Mattson, Stuart Maudsley
Proton NMR analysis of plasma is a weak predictor of coronary artery disease.HealthKevin M. Brindle, Heide L. Kirschenlohr, Julian L. Griffin, Sarah C. Clarke, Ranyl Rhydwen, Andrew A. Grace, Peter M. Schofield, James C. Metcalfe
Public funding for Alzheimer disease research in the United States.HealthRichard J. Hodes
Putting the heat on febrile seizures.HealthRicardo Tapia
Quantification of antibody responses against multiple antigens of the two infectious forms of vaccinia virus provides a benchmark for smallpox vaccination.HealthGeoffrey L. Smith, Mike M. Putz, Claire M. Midgley, Mansun Law
Quantifying viable virus-specific T cells without a priori knowledge of fine epitope specificity.HealthMark K. Slifka, Carol Beadling
Quantitative imaging of plasmodium transmission from mosquito to mammal.HealthRobert Menard, Spencer Shorte, Rogerio Amino, Sabine Thiberge, Beatrice Martin, Susanna Celli, Friedrich Frischknecht
Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival.HealthSu-Jin Kim, Doris J. Doudet, Andrei R. Studenov, Cuilan Nian, Thomas J. Ruth, Sanjiv Sam Gambhir, Christopher H.S. McIntosh
Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry.HealthStephen C. De Rosa, Michael R. Betts, Richard A. Koup, Mario Roederer, David A. Price, Pratip K. Chattopadhyay, Joanne Yu, Theresa F. Harper, Emma Gostick, Stephen P. Perfetto, Paul Goepfert, Marcel P. Bruchez
Questions linger about unexplained gene-therapy trial death.HealthAlison Abbott
rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.HealthLeonard Meuse, Eric Finn, Jeffrey S. Chamberlain, Paul Gregorevic, Michael J. Blankinship, James M. Allen, Charles E. Murry, Elina Minami, Miki Haraguchi, Marvin E. Adams, Stanley C. Forehner
RBP4, an unexpected adipokine.(retinol binding protein)HealthMasato Kasuga, Hiroshi Sakaue, Yoshikazu Tamori
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.HealthToshio Suda, Atsushi Hirao, Fumio Arai, Sahoko Matsuoka, Kentaro Hosokawa, Keiyo Takubo, Yasuo Ikeda, Keisuke Ito, Kana Miyamoto, Masaka Ohmura, Kazuhito Naka
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.(cyclic adenosine monophosphate response element binding protein)HealthAkira Yamaguchi, Tatsuhiko Kodama, Hiroshi Takayanagi, Yasuyuki Morishita, Kazuhiro Aoki, Keiichi Ohya, Tomoki Nakashima, Kojiro Sato, Ayako Suematsu, Sayaka Takemoto-Kimura, Hiroshi Asahara, Toshiyuki Takai, Talal A. Chatila, Haruhiko Bito
Remodeling after stroke.HealthBerislav V. Zlokovic
Reply to 'A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation'.HealthKrishna Rajarathnam
Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells.HealthRichard A. Van Etten, Daniela S. Krause, Ulrich H. von Andrian, Katherine Lazarides
Retinal angiogenesis in development and disease.HealthThomas W. Gardner, Ray F. Gariano
Role of deficient type III interferon-lamda production in asthma exacerbations.HealthMichael R. Edwards, Stephen T. Holgate, Marco Contoli, Simon D. Message, Vasile Laza-Stanca, Peter A.B. Wark, Nathan W. Bartlett, Tatiana Kebadze, Patrick Mallia, Luminita A. Stanciu, Hayley L. Parker, Louise Slater, Anita Lewis-Antes, Onn M. Kon, Donna E. Davies, Sergei V. Kotenko, Alberto Papi, Sebastian L. Johnston
Role of matrix metalloproteinases in delayed cortical responses after stroke.HealthDavid J. Mooney, Bing-Qiao Zhao, Sophia Wang, Xiaoying Wang, Hahn-Young Kim, Eng H. Lo, Hannah Storrie, Bruce R. Rosen
Roots and stems: Stem cells in cancer.HealthWilliam C. Hahn, Kornelia Polyak
Schizophrenia: Signals from the other side.HealthGerald D. Fischbach
Scientists, activists sue South Africa's AIDS 'denialists'.(South African Medical Association and Treatment Action Campaign)HealthJames Watson
Scientists assail South Africa's 'vanity' publications.HealthChristina Scott
Scientists eye embryo-free methods to derive stem cells.HealthBruce Goldman
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants.HealthKlas Karre, Hans-Gustaf Ljunggren, Cornelis J.M. Melief, Jan Wouter Drijfhout, Thorbald van Hall, Marjet Roseboom, Ad De Jong, Frits Koning, Elisabeth Z. Wolpert, Sandra Bres, Kees Franken, Marcel Camps, Peter van Veelen, Per Grufman, Antoinette Teixeira, Ferry Ossendorp, Sandra Laban, Arnoud de Ru, Rob Valentijn, Michael Van Der Veer, Hugo Meiring
Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing.HealthJonathan M. Rothberg, Pasi A. Janne, Michael Egholm, Torstein Tengs, William R. Sellers, Matthew Meyerson, Levi A. Garraway, Jeffrey C. Lee, Elizabeth Nickerson, Michael T. Ronan, Thomas Roman K., Jan F. Simons, Yuki Yuza, Thomas LaFramboise, Kinjal Shah, Keith O'Neill, Hidefumi Sasaki, Neal Lindeman, Kwok-Kin Wong, Ana M. Borras, Edward J. Gutmann, Konstantin H. Dragnev, Ralph DeBiasi, Tzu-Hsiu Chen, Karen A. Glatt, Heidi Greulich, Desany Brian, Christine K. Lubeski, William Brokman, Pablo Alvarez, Stephen K. Hutchinson, J.H. Leamon, Gregory Turenchalk
Side effects may include evolution.HealthRyan T. Cirz, Neill Gingles, Floyd E. Romesberg
Sirt1: A metabolic master switch that modulates lifespan.HealthPer-Olof Berggren, Ingo B. Leibiger
Skin controls immune regulators.HealthShimon Sakaguchi, Tomoyuki Yamaguchi
Smoking gun.(cigarette smoking causes lung cancer )HealthEzzie Hutchinson
Snake bites and bee stings: the mast cell strikes back.HealthJuan Rivera
Soluble endoglin contributes to the pathogenesis of preeclampsia.HealthFranklin H. Epstein, Vikas P. Sukhatme, Patricia A. D'Amore, Michelle Letarte, Drucilla Roberts, S. Ananth Karumanchi, Yuval Bdolah, Shivalingappa Venkatesha, Mourad Toporsian, Chun Lam, Jun-ichi Hanai, Tadanroi Mammoto, Yeon M. Kim, Lim Kee-Hak, Hai-Tao Yuan, Towia A. Libermann, Isaac E. Stillman, Roberto Romero
South Korea scandal rocks stem cell community.HealthDavid Cyranoski
Staying slim on a low-GABA diet.HealthBrenda Smith Richards, Hans-Rudi Berthoud
Stem cell aging: What bleach can teach.HealthToren Finkel, Jie Liu
Stem cell mobilization by beta2-agonists.HealthJose A. Cancelas, David A Williams
Stem cells: The good, bad and barely in control.HealthFred H. Gage, Christian T. Carson, Stefan Aigner
Stop or die!(cancer genetics)HealthBernd Pulverer
Stopping cancer before it colonizes.HealthCarrie Rinker-Schaeffer W., Jonathan A. Hickson
Stops along the RAS pathway in human genetic disease.HealthBenjamin G. Neel, Mohamed Bentires-Alj, Maria I. Kontaridis
Strategies to determine the biological function of microRNAs.HealthMarkus Stoffel, Matthew N. Poy, Jan Krutzfeldt
Streptococcus moves inward.(group A streptococcal infections)HealthP. Patrick Cleary
Stressed out obesity and insulin resistance.HealthJerrold M. Olefsky, Carl de Luca
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.HealthHiroyuki Nakai, Mark A. Kay, Alvin Luk, Keith Hoots, Glenn F. Pierce, Margaret Ragni, Katherine A. High, Catherine S. Manno, Valder R. Arruda, Bertil Glader, John Rasko, Margareth C. Ozelo, Philip Blatt, Barbara Konkle, Michael Dake, Robin Kaye, Mahmood Razavi, Albert Zajko, James Zehnder, Amy Chew, Debra Leonard, J. Fraser Wright, Ruth R. Lessard, Sommer Jurg M., Michael Tigges, Denise Sabatino, Haiyan Jiang, Federico Mingozzi, Linda Couto, Hildegund C. Ertl
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action.HealthEric J. Nestler, Rachel L. Neve, Olivier Berton, Nadia M. Tsankova, William Renthal, Arvindz Kumar
Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain.HealthMatthias Klugmann, Anke Tappe, Ceng Luo, David Hirlinger, Nitin Agarwal, Justus Benrath, Markus U. Ehrengruber, Matthew J. During, Rohini Kuner
Systematic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology.HealthQi Long Lu, Terence A. Partridge, Julia Alter, Fang Lou, Adam Rabinowitz, HaiFang Yin, Jeffrey Rosenfeld, Steve D. Wilton
Taking the brake off T cells in chronic viral infection.HealthBarbara Rehermann, Eui-Cheol Shin
Taming the clot-buster tPA.(tissue plasminogen activator)HealthTed M. Dawson, Valina L. Dawson
Targeted cancer therapeutics: The heartbreak of success.HealthDouglas L. Mann
Targeted cancer treatment: Resisting arrest.HealthDominik Wodarz
Targeting of CD44 eradicates human acute myeloid leukemic stem cells.HealthJohn E. Dick, Liqing Jin, Kristin J. Hope, Qiongli Zhai, Florence Smadja-Joffe
T cells take the inside track.HealthPeter Openshaw
Teaming up for transformation.(cellular transformation)HealthNicola McCarthy
Teasing out the tangles.HealthKonrad Beyreuther, Stefan Kins
Telomeres and telomerase: The path from maize, tetrahymena and yeast to human cancer and aging.HealthCarol W. Greider, Jack W. Szostak, Elizabeth H. Blackburn
Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis.HealthMai H. Tran, Malcolm K. Jones, Donald P. McManus, Jeffrey M. Bethony, Alex Loukas, Mark S. Pearson, Danielle J. Smyth, Mary Duke, Tegan A. Don, Rodrigo Correa-Oliveira
TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.HealthTakashi Yamamoto, Yoshimi Nakagawa, Mika Furusawa, Hitoshi Shimano, Hiroaki Suzuki, Tomohiro Yoshikawa, Noriyuki Inoue, Hirohito Sone, Tomohiro Ide, Takashi Matsuzaka, Hideo Toyoshima, Mariko Tamura, Akimitsu Takahashi, Alyssa H. Hasty, Naoya Yahagi, Nobuhiro Yamada
The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection.HealthLaszlo Kovacs, Birgitta Agerberth, Gudmundur H. Gudmundsson, Tomas Hokfelt, Milan Chromek, Zuzana Slamova, Peter Bergman, L'udmila Podracka, Ingrid Ehren, Richard L. Gallo, Annelie Brauner
The autoimmune regulator (Aire) controls iNKT cell development and maturation.HealthTerry L. Delovitch, Li Zhou, Qing-Sheng Mi, Zhong-Bin Deng, Zai-Zhao Wang, Sarah Eckenrode, Ratanmani Joshi, Dalam Ly, Bing Yi , Jin-Xiong She
The enemy within.(factors causing breast cancer are researched)HealthJoanna Owens
The human touch.(cancer research)HealthChris Gunter
The humoral side of insulin resistance.HealthMitchell A. Lazar
The matrix degrades, neutrophils invade.HealthPeter M. Henson, R. William Vandivier
The needle in the haystack.(reserach on cancer stem cells)HealthMyrto Raftopoulou
The players on the (gamma)-secretase team.HealthAkihiko Takashima, Masafumi Shimojo, Benjamin Wolozin
The road less travelled.(cell transformation)HealthTanita Casci
The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis.HealthJason K. Kim, Gerald I. Shulman, Mylene Perreault, Andre Marette, Sebastien Bergeron, Marie-Julie Dubois, Hyo-Jeong Kim, Luce Dombrowski, Benedicte Fournes, Robert Faure, Martin Olivier, Nicole Beauchemin, Katherine A. Siminovitch
The tangled path to glucose production.(cyclic adenosine monophosphate used to treat diabetes)HealthDomenico Accili, Michihiro Matsumoto
The ups and downs of A(beta).HealthDennis J. Selkoe
Through the looking glass.(research on chromosomes)HealthJoseph G. Gall
Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotrophic virus type I.HealthYasuko Tsunetsugu-Yokota, Takeshi Kurata, Tetsutaro Sata, William W. Hall, Hideki Hasegawa, Hidehiro Takahashi, Hirofumi Sawa, Harutaka Katano, Junichiro Matsuda, Martha J. Lewis, Yasuko Orba, Takeshi Ichinohe, Noreen Sheehy, Yoshie Yamamoto, Kazuo Nagashima
TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis.HealthTakashi Kobayashi, Laurence A. Turka, Carolyn G. King, Pedro J. Cejas, Taesoo Kim, Kwiyeom Yoon, Gregory K. Kim, Elise Chiffoleau, Somia P. Hickman, Patrick T. Walsh, Yongwon Choi
Transcription meets metabolism in neurodegeneration.HealthChristopher A. Ross, Leslie Michels Thompson
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.HealthJames C. Sacchettini, Catherine Vilcheze, William R. Jacobs Jr., Feng Wang, Laurent Kremer, Masayoshi Arai, Manzour Hernando Hazbon, Roberto Colangeli, Torin R. Weisbrod, David Alland
Trial set to test how stem cells heal a broken heart.HealthGeorge S. Mack
Tumor metastasis: Mechanistic insights and clinical challenges.HealthPatricia S. Steeg
Turning neurogenesis up a notch.HealthDavid A. Greenberg, Kunlin Jin
Tyrosine kinases: Maiming myelin in leprosy.HealthRobin J.M. Franklin, Chao Zhao
UK eyes single source of funds for biomedical research.HealthXavier Bosch
Upregulation of PD-1 expression on HIV-specific CD[8.sup.+] T cells leads to reversible immune dysfunction.(programmed death)(Clinical report)HealthJean-Pierre Routy, Rafick-Pierre Sekaly, Lydie Trautmann, Loury Janbazian, Nicolas Chomont, Elias A. Said, Sylvain Gimmig, Benoit Bessette, Mohamed-Rachid Boulassel, Eric Delwart, Homero Sepulveda, Robert S. Balderas, Elias K. Haddad
US marijuana laws clamping the lid on pot research.(California. Compassionate Use Act of 1996)HealthBrian Vastag
v-ATPase [V.sub.O] subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation.HealthToshio Suda, Takeshi Miyamoto, Yongwon Choi, Seoung-Hoon Lee, Jaerang Rho, Daewon Jeong, Jai-Yoon Sul, Taesoo Kim, Nacksung Kim, Ju-Seob Kang, Sun-Kyeong Lee, Robert J. Pignolo, Boguslawa Koczon-Jaremko, Joseph Lorenzo
Vav3 proto-oncogene deficiency leads to sympathetic hyperactivity and cardiovascular dysfunction.HealthVincent Sauzeau, Maria A. Sevilla, Juan V. Rivas-Elena, Enrique de Alava, Maria J. Montero, Jose M. Lopez-Novoa, Xose R. Bustelo
VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis.(vascular endothelial growth factor)HealthRandall S. Johnson, John S. Rudge, George D. Yancopoulos, Richard C. Mulligan, Stanley L. Schrier, Joseph A. Garcia, Betty Y.Y. Tam, Kevin Wei, Jana Hoffman, Joceyln Holash, Sang-ki Park, Jenny Yuan, Colleen Hefner, Cecile Chartier, Jeng-Shin Lee, Shelly Jiang, Nihar R Niyak, Frans A. Kuypers, Ma Lisa, Uma Sundram, Grace Wu, Jacquelyn J. Maher, Calvin J. Kuo
Venture science: Climbing the ladder to telomerase, cognitive therapy and in situ hybridization.HealthJoseph L. Goldstein
Vessel tone remodeling.(vasodilatation)HealthGeoffery Burnstock
VGEF inhibitors make blood.(vascular endothelial growth factor)HealthPeter Carmeliet, Edward M. Conway, Christian Fischer
Viral nanoparticles as tools for intravital vascular imaging.HealthJohn D. Lewis, Giuseppe Destito, Andries Zijlstra, Maria Gonzalez, James P. Quigley, Marianne Manchester, Heidi Stuhlmann
Virtual models best live cells at predicting biology.HealthAlan Dove
Viruses and microRNAs.HealthBryan R. Cullen
Virus smuggling, tax evasion and tumor assassination.HealthRichard Vile, Kevin Harrington
Weaned from the needle.(inflammatory T cell-mediated diseases)HealthLucienne Chatenoud
When the clock stops ticking, metabolic syndrome explodes.HealthBart Staels
Where the chips fall.HealthKris Novak
Will travel restrictions control the international spread of pandemic influenza?Health 
Your cheatin' heart.(research fraud)HealthDavid Cyranoski
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