| Genes & Development 2006 |
| Title | Subject | Authors |
|---|
| A 5' RNA element promotes dengue virus RNA synthesis on a circular genome. | Biological sciences | Claudia V. Filomatori, Maria F. Lodeiro, Diego E. Alvarez, Marcelo M. Samsa, Lfa Pietrasanta, Andrea V. Gamarnik |
| A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression. | Biological sciences | Aimee Shen, Angelika Grundling, Heather D. Kamp, Darren E. Higgins |
| A cancer cell metalloprotease triad regulates the basement membrane transmigration program. | Biological sciences | Stephen J. Weiss, Edward Allen, Kevin Hotary, Xiao-Yan Li, Susan L. Stevens |
| A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. | Biological sciences | Myles Brown, Jason S. Carroll, Jerome Eeckhoute, Timothy R. Geistlinger, Maria I. Torres-Arzayns |
| Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast. | Biological sciences | Michael Grunstein, Feng Xu, Kangling Zhang, Catherine B. Millar |
| Acetylation of Stat1 modulates NF-kappaB activity. | Biological sciences | Oliver H. Kramer, Roland H. Stauber, Daniela Baus, Manuel Grez, Shirley K. Knauer, Edith Pfitzner, Stefan Stein, Thorsten Heinzel, Elke Jager |
| Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli. | Biological sciences | Matthias Mann, Kenn Gerdes, Thomas Kruse, Blagoy Blagoev, Masaaki Wachi, Noritaka Iwai, Anders Lobner-Olesen, Kumi Sasaki |
| Adaptor protein Ste50p links Ste11p MEKK to the HOG pathway through plasma membrane association. | Biological sciences | Cunle Wu, Gregor Jansen, Jianchun Zhang, David Y. Thomas, Malcolm Whiteway |
| A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana.(Report) | Biological sciences | Herve Vaucheret, David P. Bartel, Ramya Rajagopalan, Jerry Trejo |
| A dynamic, mitotic-like mechanism for bacterial chromosome segregation. | Biological sciences | Matthew K. Waldor, Michael A. Fogel |
| Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-[beta] signaling in cooperation with active Kras expression.(Report) | Biological sciences | Christopher V.E. Wright, Harold L. Moses, Yoshio Fujitani, Hideaki Ijichi, Anna Chytil, Agnieszka E. Gorska, Mary E. Aakre, Shuko Fujitani |
| A glycolytic enzyme, enolase, is recruited as a cofactor of tRNA targeting toward mitochondria in Saccharomyces cerevisiae. | Biological sciences | Nina Entelis, Irina Brandina, Piotr Kamenski, Igor A. Krasheninnikov, Robert P. Martin |
| A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila. | Biological sciences | Melanie Douziech, Malha Sahmi, Gino Laberge, Marc Therrien |
| A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C. | Biological sciences | Jose M. Gonzalez, Carmen Ivorra, Markus Kubicek, Silvia M. Sanz-Gonzalez, Alberto Alvarez-Barrientos, Jose-Enrique O'Connor, Brian Burke, Vicente Andres |
| A mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans. | Biological sciences | Keith R. Yamamoto, Stefan Taubert, Marc R. Van Gilst, Malene Hansen |
| A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin. | Biological sciences | Juan F. Gimenez-Abian, Catherine A. Andrews, Vas Amit C., Brian Meier, Laura A. Diaz-Martinez, Julie Green, Stacy L. Erickson, Kristyn E. VanderWaal, Wei-Shan Hsu, Duncan J. Clarke |
| An architectural map of the anaphase-promoting complex. | Biological sciences | David O. Morgan, Brian R. Thornton, David P. Toczyski, Tessie M. Ng, Mary E. Matyskiela, Christopher W. Carroll |
| An MMP liberates the Ninjurin A ectodomain to signal a loss of cell adhesion.(matrix metalloproteins) | Biological sciences | Shuning Zhang, Gina M. Dailey, Elaine Kwan, Bernadette M. Glasheen, Gyna E. Sroga, Andrea Page-McCaw |
| A novel class of small RNAs in mouse spermatogenic cells. | Biological sciences | Zhong Wang, Shane T. Grivna, Haifan Lin |
| A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb. | Biological sciences | Frederic Relaix, Didier Rocancourt, Lola Bajard, Mounia Lagha, Philippe Daubas, Margaret E. Buckingham |
| A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. | Biological sciences | Mitchell A. Lazar, Donald F. Hunt, Jun Qin, Yun Li, Benjamin A. Garcia, Jeffrey Shabanowitz, Gary D. Kao, Caroline Phelan |
| A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. | Biological sciences | Anton Wutz, Edith Heard, Patricia Le Baccon, Julie Chaumeil |
| Anterior-posterior differences in vertebrate segments: Specification of trunk and tail somites in the zebrafish blastula. | Biological sciences | Scott A. Holley |
| A pathway in quiescent cells that controls p27(super Kip1) stability, subcellular localization, and tumor suppression. | Biological sciences | Arnaud Besson, Mark Gurian-West, Xueyan Chen, Karen S. Kelly-Spratt, Christopher J. Kemp, James Roberts M. |
| A PHD finger protein involved in both the vernalization and photoperiod pathways in Arabidopsis. | Biological sciences | Robert J. Schmitz, Sibum Sung, Richard M. Amasino |
| A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. | Biological sciences | Matthias Wilm, Wolfgang Fischle, Thomas Kocher, Malgorzata Schelder, Tetyana Klymenko, Bernadett Papp, Cornelia Fritsch, Brigitte Wild, Jurg Muller |
| A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. | Biological sciences | Moshe Oren, Hiroshi Nojima, Ayelet Shmueli, Yael Aylon, Dan Michael, Norikazu Yabuta |
| A positive feedback loop couples Ras activation and CD44 alternative splicing. | Biological sciences | Michael B. Yaffe, Phillip A. Sharp, Chonghui Cheng |
| A role for the catalytic ribonnucleoprotein RNase P in RNA polymerase III transcription. | Biological sciences | Robert Reiner, Yitzhak Ben-Asouli, Ilana Krilovetzky |
| A simple principle to explain the evolution of pre-mRNA splicing. | Biological sciences | Jose-Maria Izquierdo, Juan Valcarcel |
| ASPP2 is a haploinsuffcient tumor suppressor that cooperates with p53 to suppress tumor growth. | Biological sciences | Xin Lu, Virginie Vives, Jian Su, Shan Zhong, Robert Goldin, Indrika Ratnayaka, Elizabeth Slee |
| Assembly of an active translation initiation factor complex by a viral protein. | Biological sciences | Derek Walsh, Ian Mohr |
| Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts.(Report) | Biological sciences | William Chia, Ulrike Heberlein, Fengwei Yu, Hongyan Wang, Gregory W. Somers, Arash Bashirullah |
| Auxin biosynthesis by the YUCCA flavin monooxygenases controls the formation of floral organs and vascular tissues in Arabidopsis. | Biological sciences | Youfa Cheng, Yunde Zhao, Xinhua Dai |
| Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. | Biological sciences | Akio Yamashita, Shigeo Ohno, Isoa Kashima, Natsuko Dreyfuss, Natsuko Izumi, Maoyuki Kataoka, Ryo Morishita, Shinichi Hoshino, Mutsuhita Ohno |
| BRCA1 ubiquitinates its phosophorylation-dependent binding partner CtIP. | Biological sciences | Richard Baer, Xiaochun Yu, Maoyi Lai, Shaung Fu, Junjie Chen |
| Brd4 links chromatin targeting to HPV transcriptional silencing. | Biological sciences | Hediye Erdjument-Bromage, Paul Tempst, Shwu-Yuan Wu, A-Young Lee, Samuel Y. Hou, Jongsook Kim Kemper, Cheng-Ming Chiang |
| Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. | Biological sciences | G. Shirleen Roeder, Hideo Tsubouchi |
| Cadherins in development: Cell adhesion, sorting, and tissue morphogenesis. | Biological sciences | W. James Nelson, Jennifer M. Halbleib |
| Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity.(indole-3-acetic acid-auxin response factor)(Report) | Biological sciences | Eva Benkova, Michael Sauer, Christian Luschnig, Jozef Balla, Justyna Wisniewska, Vilem Reinohl, Jin Friml |
| Canonical notch signaling functions as a commitment switch in the epidermal lineage. | Biological sciences | Elaine Fuchs, H. Amalia Pasolli, Cedric Blanpain |
| Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junction. | Biological sciences | Anne-Claude Gavin, Tatiana Cheusova, Rudolf Hans Brenner, Said Hashemolhosseini, Muhammad Amir Khan, Brigitte Boldyreff, Steffen Wolfgang Schubert, Jorge Allende, Heinrich Sticht, Thierry Buchou |
| Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. | Biological sciences | Cord Brakebusch, Xunwei Wu, Fabio Quondamatteo, Tine Lefever, Aleksandra Czuchra, Lutz Langbein, Hannelore Meyer, Anna Chrostek |
| C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival. | Biological sciences | Michael O. Hengartner, Marc Vidal, Ekaterini A. Kritikou, Stuart Milstein, Pierre-Olivier Vidalain, Guillaume Lettre, Erica Bogan, Kimon Doukoumetzidis, Phillip Gray, Thomas G. Chappell |
| Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis. | Biological sciences | Dirk Bohmann, Benoit Miotto, Thierry Sagnier, Helene Berenger, Jacques Pradel, Yacine Graba |
| Chromosome-wide gene-specific targeting of the Drosophila dosage compensation complex. | Biological sciences | Bas van Steensel, Peter B. Becker, Frauke Greil, Tobias Straub, Gregor D. Gilfillan, Elzo de Wit, Rosemarie Lamm |
| c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity. | Biological sciences | Erwin F. Wagner, Robert Eferl, Romeo Ricci, Martina Rath, Izabela Sumara, Grzegorz Sumara, Ewa Stepniak, Lijian Hui |
| CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop. | Biological sciences | Yi Liu, Qun He, Qiyang He, Joonseok Cha, Heng-Chi Lee, Yang Yuhong |
| CKI, there's more than one: Casein kinase I family members in Wnt and Hedgehog signaling. | Biological sciences | Mary Ann Price |
| c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. | Biological sciences | Warren S. Pear, Jon C. Aster, Stephen C. Blacklow, Michael S. Wolfe, Andrew P. Weng, John M. Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina del Bianco, Carlos G. Rodriguez, Hong Sai, John Tobias, Yeuming Li, Cathy Shachaf, Dean Felsher |
| Coactivator cross-talk specifies transcriptional output. | Biological sciences | Robert Tjian, Michael T. Marr II, Yoh Isogai, Kevin J. Wright |
| Combined ectopic expression of Pdx 1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue. | Biological sciences | Solomon Afelik, Yonglong Chen, Tomas Pieler |
| Condensin is required for chromosome arm cohesion during mitosis. | Biological sciences | Brigitte D. Lavoie, Erica A. Peterson |
| Constricting restricted transcription: The (actively?) shrinking web. | Biological sciences | James Douglas Engel, Peter Fraser |
| Control of cellular senescence by CPEB.(cytoplasmic polyadenylation element-binding protein) | Biological sciences | Roger J. Davis, Irina Groisman, Joel D. Richter, Norman J. Kennedy, Maria Ivshina, Veronica Marin |
| Control of leaf vascular patterning by polar auxin transport. | Biological sciences | Jiri Friml, Enrico Scarpella, Danielle Marcos, Thomas Berleth |
| Control of ribonucleotide reductase localization through an anchoring mechanism involving WTM1. | Biological sciences | Stephen J. Elledge, David Lee Yang |
| Control of translation and mRNA degradation by miRNAs and siRNAs. | Biological sciences | Roy Parker, Gregory J. Hannon, Jidong Liu, Marco Antonio Valencia-Sanchez |
| Coordination and communication between the p53 and IGF-1-aKT-TOR signal transduction pathways. | Biological sciences | Arnold J. Levine, Feng Zhaohui, Mak W. Tak, You Han, Jin Shengkan |
| Cotranscriptional processes and their influence on genome stability. | Biological sciences | James L. Manley, Xialu Li |
| Cracking the egg: Molecular dynamics and evolutionary aspects of the transition from the fully-grown oocyte to embryo. | Biological sciences | Barbara B. Knowles, Davor Solter, Alexei V. Evsikov, Joel H. Graber, J. Michael Brockman, Ales Hampl, Andrea E. Holbrook, Priyam Singh, John J. Eppig |
| Critical and distinct roles for key RET tyrosine docking sites in renal development. | Biological sciences | Jeffrey Milbrandt, Eugene M. Johnson Jr., Sanjay Jain, Mario Encinas |
| Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. | Biological sciences | Jan Kitajewski, Dennis R. Roop, Jian Wang, Vikram Devgan, G. Paolo Dotto, Bach-Cuc Nguyen, Karine Lefort, Caterina Missero, Anna Mandinova, Dario Antonini, Giusy Della Gatta, Giovanna Chiorino, Maranke I. Koster, Zhuo Zhang, Alice Tommasi de Vignano |
| Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. | Biological sciences | Rongguang Zhang, Andrzej Joachimiak, Wayne Lilyestrom, Xiaojiang S. Chen, Michael G. Klein |
| CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome. | Biological sciences | Yoshihiro Nakatani, Regina Groisman, Kiyoji Tanaka, Annick Harel-Bellan, Isao Kuraoka, Alexei F. Kisselev, Odile Chevallier, Nogaye Gaye, Thierry Magnaldo |
| CTCF mediates long-range chromatin looping and local histone modification in the Beta-globin locus. | Biological sciences | Frank Grosveld, Niels Galjart, Robert-Jan Palstra, Erik Splinter, Helen Heath, Jurgen Kooren, Petra Klous, Wouter de Laat |
| Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense. | Biological sciences | Thomas Tuschl, Nam-Hai Chua, Dinshaw J. Patel |
| Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. | Biological sciences | Lilianna Solnica-Krezel, Raymond N. DuBois, Yong I. Cha, Seok-Hyung Kim, Diane Sepich, F. Gregory Buchanan |
| Cytokines regulate postnatal hematopoietic stem cell expansion: Opposing roles of thrombopoietin and LNK. | Biological sciences | Hong Qian, Robert Mansson, Natalija Buza-Vidas, Christina T. Jensen, Kristina Anderson, Jennifer Antonchuk, Sidinh Luc, Sasan Zandi, Satoshi Takaki, Jens M. Nygren, Sten Eirik W. Jacobsen |
| DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. | Biological sciences | Yaxue Zeng, Chad M. McCall, Yizhou Joesph He |
| Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1[alpha]/LRP130 complex. | Biological sciences | Marcus P. Cooper, Lishu Qu, Jiandie Lin; Spiegelman, Bruce M. |
| Deficiency of Rbbp1/Arid4a and Rbbp1/1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain.(Prader-Willi syndrome/Angelman syndrome)(Report) | Biological sciences | Arthur L. Beaudet, Mei-Yi Wu, Ting-Fen Tsai |
| Defining the transcriptional redundancy of early bodywall muscle development in C. elegans: Evidence for a unified theory of animal muscle development.(Report) | Biological sciences | Tetsunari Fukushige, Thomas M. Brodigan, Lawrence A. Schriefer, Robert H. Waterson, Michael Krause |
| Denoising feedback loops by thresholding - A new role for microRNAs.(Report) | Biological sciences | Stephen M. Cohen, Julius Brennecke, Alexander Stark |
| Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain.(Report) | Biological sciences | Claudia Mertens, Minghao Zhong, Ravi Krishnaraj, Wenxin Zou, Xiaomin Chen |
| Depression of Her-2 uORF is mediated by a novel post-transcriptional control mechanism in cancer cells. | Biological sciences | Stuart W. Peltz, Christopher R. Trotta, Anuradha Mehta |
| Development requires activation but not phosphorylation of beta1 integrins. | Biological sciences | Yuliya Pylayeva, Filippo G. Giancotti |
| Differential effects of PER2 phosphorylation: Molecular basis for the human familial advanced sleep phase syndrome (FASPS). | Biological sciences | Andreas Herrmann, Katja Vanselow, Jens T. Vanselow, Pal O. Westermark, Silke Reischl, Bert Maier, Thomas Korte, Hanspeter Herzel, Andreas Schlosser, Achim Kramer |
| Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication.(Report) | Biological sciences | Michael F. Carey, Sriharsa Pradhan, Pierre-Olivier Esteve, Hang Gyeong Chin, Andrea Smallwood, George R. Feehery, Omkaram Gangisetty, Adam R. Karpf |
| Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax. | Biological sciences | Daniel J. McKay, Joaquim Culi, Wen Zhang, Barbara Noro |
| Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. | Biological sciences | Douglas Hanahan, Christoph Peters, Thomas Reinheckel, Vasilena Gocheva, Wei Zeng, Danxia Ke, David Klimstra, Johanna A. Joyce |
| DNA damage triggers nucleotide excision repair-dependent monobiquitylation of histone H2A. | Biological sciences | Jacques Neefjes, Elisabetta Citterio, Wim Vermeulen, Jan H.J. Hoeijmakers, Steven Bergink, Li Yuan, Florian A. Salomons, Deborah Hoogstraten, Nico P. Dantama, Tom A.M. Groothuis, Adriaan B. Houtsmuller, Harm de Waard, Junxin Wu |
| DNA methylation regulates long-range gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner.(Report) | Biological sciences | Masaki Okano, Hiroshi Sasaki, En Li, Masaaki Oda, Akiko Yamagiwa, Shinji Yamamoto, Takao Nakayama, Akiko Tsumura, Kazuki Nakao |
| Does Po1 I talk to Po1 II? Coordination of RNA polymerases in ribosome biogenesis. | Biological sciences | Nouria Hernandez, Annemieke A. Michels |
| Dosage compensation in high resolution: Global up-regulation through local recruitment. | Biological sciences | Dirk Schubeler |
| Dosage compensation in mammals: Fine-tuning the expression of the X chromosome. | Biological sciences | Edith Heard, Christine M. Disteche |
| Downstream control of upstream open reading frames. | Biological sciences | Matthew S. Sachs, Adam P. Geballe |
| Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.(Report) | Biological sciences | Chris Q. Doe, Cheng-Yu Lee, Arash Bashirullah, Ryan O. Andersen, Clemens Cabernard, Laurina Manning, Khoa D. Tran, Marcus J. Lanskey |
| Drosophila lacking microRNA miR-278 are defective in energy homeostasis. | Biological sciences | Stephen M. Cohen, Aurelio A. Teleman |
| Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription.(Drosophila melanogaster ) | Biological sciences | Jian-Quan Li, Lu-Ping Liu, Daniel Hess, Jens Rietdorf, Fang-Lin Sun |
| Drosophila UNR is required for translational repression of male-specific lethal 2 mRNA during regulation of X-chromosome dosage compensation. | Biological sciences | Fatima Gebauer, Irina Abaza, Olga Coll, Solenn Patalano |
| DTL/CDT2 is essential for CDT1 regulation and the early G2/M checkpoint.(Report) | Biological sciences | Jacqueline A. Lees, Nancy Hopkins, Jennifer L. Shepard, Christopher L. Sansam, Kevin Lai, Alessandra Ianari, Paul S. Danielian, Adam Amsterdam |
| Dual degradation signals control Gli protein stability and tumor formation. | Biological sciences | Peter K. Jackson, Erik G. Huntzicker, Ivette S. Estay, Hanson Zhen, Ludmila A. Lokteva, Anthony E Oro |
| Dynamic regulatory interactions of Polycomb group genes: MEDEA autoregulation is required for imprinted gene expression in Arabidopsis. | Biological sciences | Ueli Grossniklaus, Celia Baroux, Valeria Gagliardini, Damian R. Page |
| E4F1: A novel candidate factor for mediating BMI1 function in primitive hematopoietic cells. | Biological sciences | Sylvain Meloche, Julie Lessard, Guy Sauvageau, Martin Sauvageau, Jalila Chagraoui, Sherry L. Niessen, Simon Girard, Philippe Coulombe |
| Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock. | Biological sciences | Roman V. Kondratov, Anna A. Kondratova, Victoria Y. Gorbacheva, Marina P. Antoch, Olena V. Vykhovanets |
| Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes. | Biological sciences | Robert S. Ingram, John M. Levorse, Shirley M. Tilghman, Debora Mancini-DiNardo, Scott J.S. Steele |
| Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. | Biological sciences | Peter K. Jackson, David V. Hansen, Julie J. Miller, Matthew K. Summers, Maxence V. Nachary, Norman L. Lehman, Alex Loktev |
| Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs.(Report) | Biological sciences | Robert J. Schneider, Jin-Yu Lu, Navid Sadri |
| Erasure of histone acetylation by Arabidopsis HDA6 mediates large-scale gene silencing in nucleolar dominance. | Biological sciences | Michael Gross, Olga Pontes, Craig S. Pikaard, Keith Earley, Richard J. Lawrence, Rachel Reuther, Wand Viegas, Angle J. Ensico, Manuela Silva, Nuno Neves |
| Eukaryotes learn how to count: Quorum sensing by yeast. | Biological sciences | Stephen C. Winans, George F. Sprague Jr. |
| Evidence for a novel protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in Bacillus subtilis. | Biological sciences | Richard Losick, Craig D. Ellermeier |
| Extensive post-transcriptional regulation of microRNAs and its implications for cancer. | Biological sciences | Scott M. Hammond, J. Michael Thomson, Martin Newman, Joel S. Parker, Elizabeth M. Morin-Kensicki, Tricia Wright |
| Feedback control of morphogenesis in fungi by aromatic alcohols. | Biological sciences | Gerald R. Fink, Hao Chen |
| Fertility versus disease resistance, a hard choice. | Biological sciences | Sarah Hake, Rebecca Bart, Pamela Ronald |
| FGF signaling delineates the cardiac progenitor field in the simple chordate, Ciona intestinalis. | Biological sciences | Mike Levine, Brad Davidson, Lionel Christiaen, Weiyang Shi, Jeni Beh |
| Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. | Biological sciences | Craig S. Smith, David M. Ornitz, Kory J. Lavine, Andrew C. White, Changwon Park, Kyunghee Choi, Fanxin Long |
| Full and partial genome-wide assembly and disassembly of the yeast transcription machinery in response to heat shock. | Biological sciences | Sara J. Zanton, B. Franklin Paugh |
| Functional coupling of RNAP II transcription to spliceosome assembly. | Biological sciences | Rita Das, Kobina Dufu, Ben Romney, Megan Feldt, Elenko, Mark; Reed, Robin |
| Function of the MAPK scaffold protein, Ste5, requires a cryptic domain.(mitogen-activated protein kinase ) | Biological sciences | Lindsay S. Garrenton, Susan L. Young, Jeremy Thorner |
| Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. | Biological sciences | Allan Bradley, Ronald A. Laskey, David J. Adams, Michael A. Gonzalez, Kiku-e K. Tachibana, Louise van der Weyden, Myriam Hemberger, Nicholas Coleman |
| Gene regulatory networks for the development and evolution of the chordate heart. | Biological sciences | Nori Satoh, Yutaka Satou |
| Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program. | Biological sciences | Beverly M. Emerson, Nathan P. Gomes, Glen Bjerke, Briardo Llorente, Stephanie A. Szostek, Joaquin M. Espinosa |
| Genetic and pharmacological evidence that a retinoic acid cannot be the RXR- activating ligand in mouse epidermis keratinocytes. | Biological sciences | Mei Li, Nadia Messaddeq, Daniel Metzger, Pierre Chambon, Cecile Calleja, Benoit Chapellier, Haiyuan Yang, Wojciech Krezel, Benedicte Mascrez, Kiminori Ohta, Hiroyuki Kagechika, Yasuyuki Endo, Manel Mark, Norbert B. Ghyselink |
| Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development.(Caenorhabditis elegans ) | Biological sciences | Min Han, Yo Suzuki |
| Genetic regulation of bone mass and susceptibility to osteoporosis. | Biological sciences | Stuart H. Ralston, Benoit de Cromburgghe |
| Genetics and biology of pancreatic ductal adenocarcinoma. | Biological sciences | Ronald A. DePinho, Nabeel Bardeesy, Aram F. Hezel, Alec C. Kimmelman, Ben Z. Stagner |
| Genome-wide analysis identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. | Biological sciences | Yuh Nung Jan, Lily Yeh Jan, Jay Z. Parrish, Michael D. Kim |
| Genome-wide identification of replication origins in yeast by comparative genomics. | Biological sciences | Conrad A. Nieduszynski, Yvonne Knox, Anne D. Donaldson |
| Genome-wide mapping of Polycomb target genes unravel their roles in cell fate transitions. | Biological sciences | Kristian Helin, Adrian P. Bracken, Nikolaj Dietrich, Diego Pasini, Klaus H. Hansen |
| Genomic instability due to V(D)J recombination-associated transposition. | Biological sciences | Yeturu V.R. Reddy, Eric J. Perkins |
| Hda-mediated inactivation of the DnaA protein and dnaA gene autoregulation act in concert to ensure homeostatic maintenance of the Escherichia coli chromosome. | Biological sciences | Anders Lobner-Olesen, Leise Riber, Jan A. Olsson, Rasmus B. Jensen, Ole Skovgaard, Santanu Dasgupta, Martin G. Marinus |
| Hedgehog/Ras interactions regulate early stages of pancreatic cancer.(Report) | Biological sciences | Matthias Hebrok, Andrzej A. Dlugosz, Marina Pasca Di Magliano, Shigeki Sekine, Alexandre Ermilov, Jenny Ferris |
| Hedgehog-regulated localization of Vax2 controls eye development.(Report) | Biological sciences | Greg Lemke, Jin Woo Kim |
| Hedgehog signaling and the retina: Insights into the mechanisms controlling the proliferative properties of neural precursors. | Biological sciences | William A. Harris, Morgane Locker, Michalis Agathocleous |
| Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication. | Biological sciences | Titia de Lange, Eros Lazzerini Denchi, Giulia Celli |
| HIF1[alpha] delays premature senescence through the activation of MIF.(hypoxia-inducible factor 1)(macrophage migration inhibitory factor)(Report) | Biological sciences | Amato J. Giaccia, Lorenz Poellinger, Scott M. Welford, Barbara Bedogni, Katarina Gradin, Marianne Broome Powell |
| HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth. | Biological sciences | M. Celeste Simon, Kelly L. Covello, James Kehler, Brian Keith, Hongwei Yu, John D. Gordan, Patricia A. Labosky, Andrew M. Arsham, Cheng-Jun Hu |
| HIF and MIF-a nifty way to delay senescence?(hypoxia-inducible factor-1)(macrophage inhibitory factor)(Report) | Biological sciences | Amit Maity, Constantinos Koumenis |
| High resolution ChIP-chip analysis reveals that Drosophila MSL complex selectivity identifies active genes on the male X chromosome. | Biological sciences | Mitzi I. Kuroda, Erica Larschan, Peter J. Park, Artyom A. Alekseyenko, Weil R. Lai |
| Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors. | Biological sciences | Lei Wang, Harini Rajan, Jeffrey L. Pitman, Michael McKeown, Chih-Cheng Tsai |
| Histone H3 Lys 4 methylation: Caught in a bind.(Report) | Biological sciences | Danny Reinberg, Robert J. Sims III |
| Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. | Biological sciences | Li-Lin Du, Toru M. Nakamura |
| Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. | Biological sciences | William S. Lane, David E. Sterner, Erica S. Johnson, Dafna Nathan, Jean A. Dorsey, Kristin Ingvarsdottir, Kelly A. Whelan, Shelly L. Berger, Mihajlo Krsmanovic, Gwendolyn R. Bylebyl, Milos Dokmanovic, Pamela B. Meluh |
| Histone trimethylation and the maintenance of transcriptional on and off states by trxG and PcG proteins. | Biological sciences | Bernadett Papp, Jurg Muller |
| Human telomerase and Cajal body ribonucleoproteins share a unique specificity of Sm protein association. | Biological sciences | Kathleen Collins, Dragony Fu |
| Identification and characterization of two novel classes of small RNAs in the mouse germline: Retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. | Biological sciences | Toshiaki Watanabe, Hiroyuki Sasaki, Kazuyuki Mise, Tetsuro Okuno, Tomoyuki Tsukiyama, Atsushi Takeda, Naojiro Minami, Hiroshi Imas |
| Identification of a novel regulatory protein (CsrD) that targets that global regulatory RNAs CsrB and CsrC for degradation by RNase E. | Biological sciences | Kazushi Suzuki, Paul Babitzke, Sidney R. Kushner, Tony Romeo |
| Identification of phosphatases for Smad in the BMP/DPP pathway. | Biological sciences | Hong B. Chen, Jiali Shen, Y. Tony Ip, Lan Xu |
| Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.(Report) | Biological sciences | Ken Inoki, Kun-Liang Guan, Qian Yang, Tsuneo Ikenoue |
| Imprinting mechanisms-it only takes two. | Biological sciences | Denise P. Barlow, Florian M. Pauler |
| Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer.(Report) | Biological sciences | Steven P. Gygi, Julie Huang, Danesh Moazed, Angelika Amon, Ilana L. Brito, Judit Villen |
| Inositol monophosphatase regulates localization of synaptic components and behavior in the mature nervous systems of C. elegans. | Biological sciences | Yoshinori Tanizawa, Hitoshi Inada, Ikue Mori |
| Insulin-like signaling and the neural circuit for integrative behavior in C. elegans. | Biological sciences | Akiko Mohri-Shiomi, Atsushi Kuhara, Eiji Kodama, Koutarou D. Kimura |
| Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart. | Biological sciences | Hugo A. Katus, Mark C. Fishman, Garnet Bendig, Mathias Grimmler, Inken G. Huttner, Georgia Wessels, Tillman Dahme, Steffan Just, Nicole Trano, Wolfgang Rottbauer |
| Interplay between Ino80 and Swrl chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. | Biological sciences | Craig L. Peterson, Manolis Papamichos-Chronakis, Jocelyn E. Krehs |
| In vivo beta1 integrin function requires phosphorylation-independent regulation by cytoplasmic tyrosines. | Biological sciences | Hong Chen, Eric Sebzda, Zhiying Zou, Daniel A. Hammer, Kendra L. Sarratt, Mark L. Kahn, Diane Zhou, MaoZhen Zhang |
| In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants. | Biological sciences | Michael Rosbash, Scott A. Lacadie, Daniel F. Tardiff, Sebastian Kadener |
| Jab1 is a specificity factor for E2F1-induced apoptosis. | Biological sciences | Joseph R. Nevins, Timothy C. Hallstrom |
| Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells. | Biological sciences | Barna D. &Fodor, Stefan &Kubicek, Masato &Yonezawa, Roderick J. &O'Sullivan, Gunnar &Schotta, Roopsha, Laura &Perez-Burgos, Susanne &Opravil |
| Keratin 17 modulates hair follicle cycling in a TNF[alpha]-dependent fashion. | Biological sciences | Pierre A. Coulombe, Xuemei Tong |
| Keystone meeting summery: 'Adipogenesis, obesity, and inflation' and 'diabetes mellitus and the control of cellular energy metabolism,' January 21-26, 2006, Vancouver, Canada. | Biological sciences | Philipp E. Scherer, Silvia Corvera, Alison Burkart, Zhao Wang, Ja-Young Kim |
| Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation. | Biological sciences | Brian K. Kennedy, Richard L. Frock, Brian A. Kudlow, Angela M. Evans, Samantha A. Jameson, Stephen D. Hauschka |
| Leukemia and lymphoma: A cost of doing business for adaptive immunity. | Biological sciences | Mark S. &Schlissel, Chris R. &Kaffer, John D. &Curry |
| Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis. | Biological sciences | Thomas Boller, Silke Robatzek, Delphine Chinchilla |
| Loss of transforming growth factor-[beta] type II receptor promotes metastatic head-and-neck squamous cell carcinoma. | Biological sciences | Shi-Long Lu, Heather Herington, Douglas Reh, Christopher L. Corless, Xiao-Jing Wang, Stephen Weber, Yasmin Sidiqqui, Jo Nord, Peter Andersen, Sophia Bornstein, Donna Wang, Allen G. Li, Chin-Fang Tang |
| Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. | Biological sciences | Harold E. Varmus, Katrina Politi, Maureen F. Zokowski, Pang-Dian Fan, William Pao, Emily A. Schonfeld |
| Malignant melanoma: Genetics and therapeutic in the genomic era. | Biological sciences | David E. Fisher, Lynda Chin, Levi A. Garraway |
| Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. | Biological sciences | Leonard Guarente, Ingrid Grummt, Ethan Ford, Renate Voit, Gregory Liszt, Cornelia Magin |
| Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. | Biological sciences | Marcia C. Haigis, Leonard P. Guarente |
| Mammalian sperm translate nuclear-encoded proteins by mitochondrial-type ribosomes. | Biological sciences | Yael Gur, Haim Breitbart |
| Maternal BRG1 regulates zygotic genome activation in the mouse. | Biological sciences | Scott J. Bultman, Richard M. Schultz, Petr Svoboda, Thomas C. Gebuhr, Terry Magnuson, Hua Pan |
| MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres. | Biological sciences | Titia de Lange, Nadya Dimitrova |
| Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway. | Biological sciences | Hao Zhang, Rakesh Kumar, Amjad H. Talukder |
| MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila.(Report) | Biological sciences | Yan Li, Fay Wang, Jin-A Lee, Fen-Biao Gao |
| Mitf regulation of Dia1 controls melanoma proliferation and invasiveness.(Report) | Biological sciences | Colin R. Goding, Alessandro Testori, Jane Goodall, Mercedes Rodriguez, Suzanne Carreira, Laurence Denat, Lionel Larue, Paolo Nuciforo, Keith S. Hoek |
| Modulating RssB activity: IraP, a novel regulator of sigma(super s) stability in Escherichia coli. | Biological sciences | Susan Gottesman, Sue Wickner, Alexandre Bougdour |
| Modulating the outer membrane with small RNAs. | Biological sciences | Susan Gottesman, Gisela Storz, Maude Guillier |
| Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells. | Biological sciences | Stephen L. Nutt, Donald Metcalf, Tim Thomas, Anne K. Voss, Lynn M. Corcoran, Raffi Gugasyan, Mathew P. Dixon, Thomas Brodnicki |
| MOZ is essential for maintenance of hematopoietic cells. | Biological sciences | Hitoshi Ichikawa, Takuo Katsumoto, Yukikio Aikawa, Atsushi Iwama, Shnoba Ueda, Takahiro Ochiya, Issay Kitabayashi |
| mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. | Biological sciences | Peer Bork, Alexander Stark, Elisa Izaurralde, Isabelle Behm-Ansmant, Jan Rehwinkel, Tobias Doerks |
| MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula.(Report) | Biological sciences | Martin Crespi, Jean-Philippe Combier, Florian Frugier, Francoise De Billy, Adnane Boualem, Fikri El-Yahyaoui, Sandra Moreau, Tatiana Vernie, Thomas Ott, Pascal Gamas, Andreas Niebel |
| Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. | Biological sciences | David M. Livingston, Yoshihiro Nakatani, Roger A. Greenberg, Bijan Sobhian, Shailja Pathania, Sharon B. Cantor |
| Multipotential differentiation ability of GATA-1-null erythroid-committed cells. | Biological sciences | Jie Zheng, Toru Nakano, Kenji Kitajima, Hilo Yen, Daijiro Sugiyama |
| Muscle cachexia is regulated by a p53-PW1/Peg3-dependent pathway.(Report) | Biological sciences | David Sassoon, Martina Schwarzkopf, Dario Coletti, Giovanna Marazzi |
| Muscle stem cells in development, regeneration, and disease. | Biological sciences | Daniel J. Garry, Xiaozhong Shi |
| MyoD, modularity, and myogenesis: Conservation of regulators and redundancy in C. elegans.(Report) | Biological sciences | Craig P. Hunter, L. Ryan Baugh |
| Necrotic death as a cell fate. | Biological sciences | Craig B. Thompson, Zong Wei-Xing |
| Neuronal polarity in CNS development. | Biological sciences | Mary E. Hatten, Toshifumi Tomoda, David J. Solecki, Eve-Ellen Govek |
| No exit strategy? No problem: APC inhibits beta-catenin inside the nucleus. | Biological sciences | Yue Xiong, Yojiro Kotake |
| Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity. | Biological sciences | Keith R. Yamamoto, Sebastiaan H. Meijsing, Carlos Pantoja, Jen-Chywan Wang, Nilesh Shah, Joseph D. Ho, Thomas S. Scanaln |
| Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. | Biological sciences | Ronald M. Evans, Fred H. Gage, Ruth T. Yu, Chun-Li Zhang, Yuhua Zou |
| Nucleolar dominance: A model for rRNA gene silencing. | Biological sciences | Brian McStay |
| Nucleosome displacement in transcription. | Biological sciences | Jerry L. Workman |
| p27(super Kip1) independently promotes neuronal differentiation and migration in the cerebral cortex. | Biological sciences | James M. Roberts, Lydia Teboul, Arnaud Besson, Anna Philpott, Laurent Nguyen, Julian Ik-Tsen Heng, Carol Schuurmans, Carlos Parras, Francois Guillemot |
| p63 regulates proliferation and differentiation of developmentally mature keratinocytes.(Report) | Biological sciences | Paul A. Khavari, Amy B. Truong, Todd W. Ridky, Markus Kretz, Robin Kimmel |
| Packing for the germy: The role of histone H4 Ser1 phosphorylation in chromatin compaction and germ cell development. | Biological sciences | Ali Shilatifard, Kristy Wendt |
| Pdm and castor specify late-born motor neuron identity in the NB7-1 lineage. | Biological sciences | Kristin J. Robinson, Ruth Grosskortenhaus, Doe. Chris Q. |
| PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription. | Biological sciences | Wangjie Yu, Hao Zheng, Jerry H. Houl, Brigitte Dauwalder, Paul E. Hardin |
| Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation. | Biological sciences | Christopher V.E. Wright, Eric P. Sandgren, Kiyoshi Takeda, Kaoru Yamamoto, Hideaki Kaneto, Takeshi Miyatsuka, Yoshitaka Kajimoto, Yoshimitsu Yamasaki, Yoshio Fujitani, Toshihiko Shiraiwa, Taka-aki Matsouka, Ken Kato, Yumiko Nakamura, Shizou Akira, Yoshia Kawaguchi |
| Phosphorylation and functions of the RNA polymerase II CTD. | Biological sciences | Arno L. Greenleaf, Hemali P. Phatnani |
| Phosphorylation-dependent maturation of Neurospora circadian clock protein from a nuclear repressor toward a cytoplasmic activator. | Biological sciences | Krisztina Kaldi, Michael Brunner, Tobias Schafmeier, Axel Diernfellner, Christian Mohr |
| Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. | Biological sciences | Shelley L. Berger, Margaret T. Fuller, Xin Chen, Saadi Khochbin, Thanuja Krishnamoorthy, Jerome Govin, Wang L. Cheng, Jean Dorsey, Karen Schindler, Edward Winter, C David Allis, Vincent Guacci |
| Phosphorylation of NtMAP65-1 by a MAP kinase down-regulates its activity of microtubule bundling and stimulates progression of cytokinesis of tobacco cells. | Biological sciences | Takashi Soyano, Yasunori Machida, Michiko Sasabe, Tomohiko J. Itoh, Mikiko Hidaka, Yuji Takahashi, Seiji Sonobe, Hisako Igarashi |
| PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein. | Biological sciences | Cory Abate-Shen, David L. Spector, Kannanganattu V. Prasanth, Hansol Lee, John C. Quinn, Victoria A. Swiss, Kyriakos Economides D., Marie M. Camacho |
| PIAS proteins and transcriptional regulation-more than just two SUMO E3 ligases? | Biological sciences | Andrew D. Sharrocks |
| Plant hormone receptors: Perception is everything. | Biological sciences | Peter McCourt, Brenda Chow |
| Plasticity and expanding complexity of the hepatic transcription factor network during liver development. | Biological sciences | Frank J. Gonzalez, Francois Tronche, Irene Kyrmizi, Pantelis Hatzis, Nitsa Katrakili, Iannis Talianidis |
| Polar auxin transport and patterning: Grow with the flow. | Biological sciences | Ben Scheres, Jian Xu |
| Polycomb group-dependent Cyclin A repression in Drosophila. | Biological sciences | Frederic Bantignies, Giacomo Cavalli, Jerome Dejardin, Anne-Marie Martinez, Sophie Colomb |
| Polycomb-group proteins repress the floral activator AGL19 in the FLC-independent vernalization pathway. | Biological sciences | Claudia Kohler, Wilhelm Gruissem, Olivier Leroy, Nicole Schonrock, Romaric Bouveret, Lorenzo Borghi |
| Polyglutamine neurodegenerative diseases and regulation of transcription: Assembling the puzzle. | Biological sciences | Harry T. Orr, Bright E. Riely |
| Post-transcriptional small RNA pathways in plants: Mechanisms and regulations. | Biological sciences | Herve Vaucheret |
| Precise destruction: An emerging picture of the APC.( anaphase-promoting complex )(Report) | Biological sciences | David P. Toczyski, Brian R. Thornton |
| Promoter mutations of an essential gene for pollen development result in disease resistance in rice. | Biological sciences | Jeffrey L. Bennetzen, Zhaohui Chu, Caiguo Xu, Xianghua Li, Meng Yuan, Binying Fu, Zhikang Li, Jailing Yao, Xiaojia Ge, Qifa Zhang, Bin Yuan, Shiping Wang |
| Proteolysis of MLL family proteins is essential for Tappase1-orchestrated cell cycle progression. | Biological sciences | Stanley J. Korsmeyer, James J.-D. Hsieh, Shugaku Takeda, David Y. Chen, Todd D. Westergard, Jill K. Fisher, Jeffrey A. Rubens, Satoru Sasagawa, Emily H-Y Cheng |
| Quality control of gene expression: A stepwise assembly pathway for the surveillance complex that triggers nonsense-mediated mRNA decay. | Biological sciences | Elisa Izaurralde, Isabelle Behm-Ansmant |
| Red-Hed regulation: Recombinase Rad51, though capable of playing the leading role, may be relegated to supporting Dmc1 in budding meiosis. | Biological sciences | Douglas K. Bishop, Sean Sheridan |
| Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-activating protein activity in larval neurons. | Biological sciences | Glenn S. Cowley, James A. Walker, Anna V. Tchoudakova, Dongyun Wu |
| Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway.(Report) | Biological sciences | Ichiro Shiojima, Kenneth Walsh |
| Regulation of neuroblast competence: Multiple temporal identity factors specify distinct neuronal fates within a single early competence window. | Biological sciences | Chris Q. Doe, Michael D. Cleary |
| Regulation of transcription factor latency by receptor-activated proteolysis. | Biological sciences | Claes &Andreasson, Stijn &Heessen |
| Regulon and promoter analysis of the E. coli heat-shock factor, [sigma.sup.32], reveals a multifaceted cellular response to heat stress. | Biological sciences | Carol A. Gross, Christophe Herman, Matthew Blankschien, Gen Nonaka, Virgil A. Rhodius |
| Rep and PriA helicase activities prevent RecA from provoking unnecessary recombination during replication fork repair.(Clinical report) | Biological sciences | Robert G. Lloyd, Akeel A. Mahdi, Carol Buckman, Lynda Harris |
| Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment. | Biological sciences | Stephen L. Nutt, Melissa L. Holmes, Sebastian Carotta, Lynn M. Corcoran |
| Requirement of clathrin heavy chain for p53-mediated transcription. | Biological sciences | Yoichi Taya, Issay Kitabayashi, Masato Enari, Kazuji Ohmori |
| Rho is a presynaptic activator of neurotransmitter release at pre-existing synapses in C. elegans. | Biological sciences | Paul Morrison, Rachel McMullan, Emma Hiley, Stephen J. Nurrish |
| Rhomboid proteins: Conserved membrane proteases with divergent biological functions.(Report) | Biological sciences | Sinisa Urban |
| RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress induced p21 transcript. | Biological sciences | Wensheng Yan, Xinbin Chen |
| Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.(Report) | Biological sciences | Yves Gauthier, Thierry Brue, Jacques Drouin, Andre Lacroix, Dominique Figarella-Branger, Sophie Vallette-Kasic, Steve Bilodeau, France Berthelet, Dalia Batista, Constantine Stratakis, Jeanette Hanson, Bjorn Meij |
| Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression. | Biological sciences | Yunhua Chang, Paivi Ostling, Malin Akerfelt, Diane Trouillet, Murielle Rallu, Yorick Gitton, Rachid El Fatimy, Vivienne Fardeau, Stephen Le Crom, Morange, Michel; Sistonen, Lea, Valerie Mezger |
| RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans. | Biological sciences | Michael R. Green, Haihong Shen |
| Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. | Biological sciences | Gerard Karsenty, David M. Ornitz, Peter Bialek, Marie-Therese Rached, Yon-Tzung Chen, Eiichi Hinoi, Groner, Yoram; Behringer, Richard R. |
| SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae. | Biological sciences | Bing Li, Wei-Jong Shia, Workman Jerry L. |
| Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response. | Biological sciences | Stephen T. Smale, Anthony N. Imbalzano, Vladimir R. Ramirez-Carrozzi, Aaron A. Nazarian, Li C. Caiyi, Sarah L. Gore, Rupa Sridharan |
| Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. | Biological sciences | Christopher K. Glass, Michael G. Rosenfeld, Victoria V. Lunyak |
| Sex-lethal imparts a sex-specific function to UNR by recruiting it to the msl-2 mRNA 3' UTR: Translational repression for dosage compensation. | Biological sciences | Matthias Wilm, Matthias W. Hentze, Karsten Beckmann, Ricarda Niggeweg, Marica Grskovic, Fatima Gebauer, Kent Duncan, Claudia Strein, Irina Abaza |
| SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. | Biological sciences | Hwei-Ling Cheng, Alejandro Vaquero, Michael B. Scher, Fredrick W. Alt, Lourdes Serrano, Rolf Sterglanz, Reinberg Danny |
| Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures. | Biological sciences | William G. Dunphy, Hae Yong Yoo, Seong-Yun Jeong |
| Skin epidermis lacking the c-myc is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the [p21.sup.Cip1] gene. | Biological sciences | Daniel Metzger, Pierre Chambon, Peter Beard, Thordur Oskarsson, Marieke Alida Gertruda Essers, Nicole Dubois, Sandra Offner, Christelle Dubey, Catherine Roger, Edith Hummler, Andreas Trumpp |
| Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells. | Biological sciences | Xi He, Hongyan Jian, Xing Shen, Irwin Liu, Xiao-Fan Wang |
| Smad4 is dispensable for normal pancreas development yet critical in progression and tumour biology of pancreas cancer.(Report) | Biological sciences | Douglas Hanahan, James Horner, Ronald A. DePinho, Nabeel Bardeesy, Gregory Y. Lauwers, Peter Olson, Aram F. Hezel, Kuang-hung Cheng, Justin H. Berger, Gerald C. Chu, Jessica Pahler |
| Small RNAs just got bigger: Piwi-interacting RNAs (piRNAs) in mammalian testes. | Biological sciences | V. Narry Kim |
| Some disassembly required: Role of DNA translocases in the disruption of recombination intermediates and dead-end complexes. | Biological sciences | Wolf-Dietrich Heyer, Lorraine S. Symington |
| SOX2 is a dose-dependent regulator of retinal neural progenitor competence. | Biological sciences | Olena V. Taranova, Scott T. Magness, B. Matthew Fagan, Yongqin Wu, Natalie Surzenko, Scott R. Hutton, Larysa H. Pevny |
| Sox2 is required for development of taste bud sensory cells. | Biological sciences | Brigid L.M. Hogan, Larysa H. Pevny, Tadashi Okubo |
| Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drasophila genome. | Biological sciences | Haruhiko Siomi, Keita Miyoshi, Tomoko Nagami, Kuniaki Saito, Kazumichi M. Nishida, Tomokoz Mori, Yoshinori Kawamura, Mekiko C. Siomi |
| Specific functional interactions of nucleotides at key (super -)3 and (super +)4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex. | Biological sciences | Tatyana V. Pestova, Victoria G. Kolupaeva, Christopher U.T. Hellen, William C. Merrick, Andrey V. Pisarev, Vera P. Pisareva |
| Spineless provides a little backbone for dendritic morphogenesis.(Report) | Biological sciences | Stephen T. Crews, Jay E. Brenman |
| Spleen versus pancreas: Strict control of organ interrelationship revealed by analyses of Bapx1(super -1-) mice. | Biological sciences | Nicholas D. Hastie, James Sharpe, Jacob Hecksher-Sorensen, Amir Asayesh, Robert P. Watson, Robert E. Hill, Ulf Ahlgren |
| S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner. | Biological sciences | Iain M. Hagan, Agnes Grallert, Steve Bagley, Christoph Beuter, Rachel A. Craven, Deepti Wilks, Ursula Fleig |
| Sumo-mediated regulation of synaptonemal complex formation during meiosis. | Biological sciences | Monica P. Colaiacovo, Carlos Egydio de Carvalho |
| SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of saccharomyces cerevisiae. | Biological sciences | Chung-Hsu Cheng, Yu-Hui Lo, Shu-Shan Liang, Shih-Chieh Ti, Feng-Ming Lin, Chia-Hui Yeh, Han-Yi Huang, Ting-Fang Wang |
| Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. | Biological sciences | Michael G. Rosenfeld, Jie Zhang, Jessica Tollkuhn, Ryoichiro Kageyama, Francois Guillemot, Xiaoyan Zhu, Ryosuke Ohsawa, Emery H. Bresnick |
| Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. | Biological sciences | Connie M. Weaver, Tracey C. Fleischer, Andrew J. Link, K. Jill McAfee, Jennifer L. Jennings |
| Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure.(integrim-linked kinase ) | Biological sciences | Stanley Nattel, William J. Muller, Donald E. White, Jean-Claude Tardif, Pierre Coutu, Yan-Fen Shi, Rene St. Arnaud, Shoukat Dedhar |
| Target hub proteins serve as master regulators of development in yeast. | Biological sciences | Michael Snyder, Paul Bertone, Mark Gerstein, Haiyuan Yu, Anthony R. Borneman, Justine A. Leigh-Bell |
| Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. | Biological sciences | Jeremy F. Reiter, William C. Skarnes |
| Telomerase RNA level limits telomere maintenance in X-linked Dyskeratosis congenita.(Report) | Biological sciences | Kathleen Collins, Judy M.Y. Wong |
| Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline. | Biological sciences | Mikhail Savitsky, Dmitry Kwon, Pavel Georgiev, Alla Kalmykova, Vladimir Gvozdev |
| Telomeric heterochromatin boundaries require NuA4-dependent acetylation of histone variant H2A.Z in Saccharomyces cerevisiae. | Biological sciences | Jasper Rine, Jeffrey E. Halley, Joshua E. Babiarz |
| Terminating the transcript: Breaking up is hard to do. | Biological sciences | James L. Manley, Syuzo Kaneko, Emanuel Rosonina |
| The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. | Biological sciences | Katherine A. Jones, Jose Sierra, Tomonori Yoshida, Claudio A. Joazeiro |
| The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons.(Report) | Biological sciences | Yuh Nung Jan, Lily Yeh Jan, Michael D. Kim |
| The cancer epigenome-components and functional correlates. | Biological sciences | Stephen B. Baylin, Angela H. Ting, Kelly M. McGarvey |
| The cellular roles of the lissencephaly gene LIS1 and what they tell us about brain development. | Biological sciences | Richard Vallee, Jin-Wu Tsai |
| The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling. | Biological sciences | James Briscoe, Cheryll Tickle, Maike Schmidt, Despina Stamataki, Megan G. Davey, Robert I. Paton, Yili Yin, Dave W. Burt, Mikiko Tanaka, Andrea E. Munsterberg, Fiona K. Bangs, David R. Morrice, Ternce Gordon Smith, Paul Buxton |
| The C-terminal tail of the Hedgehog receptor patched regulates both localization and turnover. | Biological sciences | Thomas B. Kornberg, Xingwu Lu, Songmei Liu |
| The deficiency of Akt1 is sufficient to suppress tumor development in [Pten.sup.?-] mice.(phosphatase and tensin homolog) | Biological sciences | Pier Paolo Pandolfi, Nissim Hay, William S. Chen, Mei-Ling Chen, Pei-Zhang Xu, Xiao-ding Peng, Grace Guzman, Ximing Yang |
| The Drosophila P68 RNA helicase regulates transcription deactivation by promoting RNA release from chromatin. | Biological sciences | Allan C. Spradling, Michael Buszczak |
| The establishment of neuronal properties is controlled by Sox4 and Sox11.(Report) | Biological sciences | Jonas Muhr, Thomas Perlmann, Maria Bergsland, Martin Werme, Michal Malewicz |
| The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. | Biological sciences | Jianchi Feng, Chunming Bi, Brian S. Clark, Rina Mady, Palak Shah, Jhumku D. Kohtz |
| The flagellar-specific transcription factor, [sigma.sup.28], is the Type III secretion chaperone for the flagellar-specific anti-[sigma.sup.28] factor FlgM. | Biological sciences | Joyce E. Karlinsey, Kelly T. Hughes, Phillip D. Aldridge, Christine Aldridge, Christopher Birchall, Danielle Thompson, Jin Yagasaki |
| The forkhead transcription factor Hcm1 regulates chromosome segregation genes and fills the S-phase gap in the transcriptional circuitry of the cell cycle. | Biological sciences | Wei Wu, Tata Pramila, Shawna Miles, William Stafford Noble, Linda L. Breeden |
| The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity. | Biological sciences | Slimane Ait-Si-Ali, Philippe Robin |
| The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. | Biological sciences | Mark Groudine, Tobias Ragoczy, M.A. Bender, Agnes Telling, Rachel Byron |
| The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. | Biological sciences | Mark Groudine, Tobias Ragoczy, M.A. Bender, Agnes Telling, Rachel Byron |
| The molecular pathogenesis of pancreatic cancer: Clarifying a complex circuitry.(Report) | Biological sciences | Anil K. Rustgi |
| The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1Beta. | Biological sciences | Gerard I. Evan, Ksenya Shehors, Elena Shehors, Panya Rostker, Elizabeth R. Lawlor, Lamorna Brown-Swigart |
| The myocardin family of transcriptional coactivators: Versatile regulators of cell growth, migration, and myogenesis. | Biological sciences | G.C. Teg &Pipes, Esther E. &Creemers, Eric N. &Olson |
| The Notch coactivator, MAML1 functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis. | Biological sciences | Roderick Bronson, James D. Griffin, Ping Gao, Huangxuan Shen, Abigail S. McElhinny, Yang Cao, Jingxuan Liu, Lizi Wu |
| The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor-signaling pathway. | Biological sciences | Jean-Yves Roignant, Sophie Hamel, Florence Janody, Jessica E. Tresiman |
| The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. | Biological sciences | Hiromi Iwasaki, Shin-ichi Mizuno, Ozawa, Hidetoshi; Tenen, Daniel G.; Akashi, Koichi |
| The regulation of mesodermal progenitor cell commitment to somitogenesis subdivides the zebrafish body musculature into distinct domains. | Biological sciences | David Kimelman, Daniel P. Szeto |
| The RhoGAP corssveinless-c links trachealess and EGFR signaling to cell shape remodeling in Drosophila tracheal invagination. | Biological sciences | Jordi Casanova, Veronique Brodu |
| The right place at the right time: Regulation of daily timing by phosphorylation. | Biological sciences | Martha Merrow, Till Roenneberg, Gabriella Mazzotta, Zheng Chen |
| The RNA silencing endonuclease argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster. | Biological sciences | Ronald P. van Rij, Bassam Berry, Maria-Carla Saleh |
| The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway. | Biological sciences | Hui-Jye Chen, Chung-Ming Lin, Chyuan-Sheng Lin, Raul Perez-Olle, Conrad L. Leung, Ronald K.H. Liem |
| The role of protein arginine methylation in the formation of silent chromatin. | Biological sciences | Dudley W. Lamming, Michael C. Yu, Julian A. Eskin |
| The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: Implications for a unified allosteric-torpedo model. | Biological sciences | David L. Bentley, Weifei Luo, Arlen W. Johnson |
| The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4. | Biological sciences | Stephen Buratowski, Laura Rocco Carpenter, Nevan J. Krogan, Jack F. Greenblatt, Michael-Christopher Keogh, Vladimir Podolny, Chika Sawa, Thomas A. Mennella, Sharon Berthelet, Adam Wolek, Kristin Baetz |
| The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes.(Report) | Biological sciences | Virginia A. Zakian, Jorge Z. Torres, Jessica B. Bessler, Anna Azvolinsky, Stephen Dunaway |
| The structural basis for regulated assembly and function of the transcriptional activator NtrC. | Biological sciences | B. Tracy Nixon, Eva Nogales, Sacha De Carlo, Baoyu Chen, Timothy R. Hoover, Elena Kondrashkina |
| The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components. | Biological sciences | Andre Sentenac, Arnaud Laferte, Emmanuel Favry, Michel Riva, Christophe Carles, Stephane Chedin |
| The transcription factor FLC confers a flowering response to vernalization by repressing meristem competence and systematic signaling in Arabidopsis.(flowering locus c) | Biological sciences | George Coupland, Yuehui He, Jain Searle, Franziska Turck, Coral Vincent, Fabio Fornara, Sandra Krober, Richard A. Amasino |
| The two Escherichia coli chromosome arms locate to separate cell halves. | Biological sciences | David J. Sherratt, Xindan Wang, Christophe Possoz, Xun Liu |
| The Vibrio harveyi quorum-sensing system uses shared regulatory components to discriminate between multiple autoinducers. | Biological sciences | Bonnie L. Bassler, Christopher M. Waters |
| The Wilms' tumor 1 (WT1) gene (KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron.(constitutive transport element) | Biological sciences | David Rekosh, Yeou-Cherng Bor, Jennifer Swartz, Avril Morrison, Michael Ladomery |
| The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic Beta cells and intestinal endocrine cells. | Biological sciences | Carmen Birchmeier, Mathias S. Gierl, Nikolaos Karoulias, Hagen Wende, Michael Streble |
| Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatin. | Biological sciences | Douglas K. Bishop, Teresa Holzen, Parisha P. Shah, Heidi A. Olivares |
| Transcriptional and post-transcriptional regulation of the circadian clock of cynobacteria and Neurospora. | Biological sciences | Michael Brunner, Tobias Schafmeier |
| Transcriptional blackjack with p21. | Biological sciences | Ali Shilatifard, Adam Wood |
| Translational resistance of late alphavirus mRNA to eIF2(alpha) phosphorylation: A strategy to overcome the antiviral effect of protein kinase PKR. | Biological sciences | Ivan Ventoso, Miguel Angel Sanz, Susana Molina, Juan Jose Berlanga, Luis Carrasco, Mariano Esteban |
| Tsix-mediated epigenetic switch of a CTCF-flanked region of the Xist promoter determines the Xist transcription program.(Report) | Biological sciences | Claire Rougeulle, Philip Avner, Pablo Navarro, Damian R. Page |
| Tumor suppression and normal aging in mice with constitutively high p53 activity. | Biological sciences | Robert N. Eisenman, Susan M. Mendrysa, Kathleen A. O'Leary, Matthew K. McElwee, Jennifer A. Michalowski, Douglas A. Powell, Mary Ellen Perry |
| Two classes of endogenous small RNAs in Tetrahymena thermophila. | Biological sciences | Kathleen Collins, Suzanne R. Lee |
| Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeast. | Biological sciences | Thomas J. Kelly, Yong-jie Xu, Matthew Davenport |
| Txr1: A transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes. | Biological sciences | Stanley N. Cohen, Chih-Jian Lih, Wensheng Wei |
| TXR1-mediated thrombospondin repression: A novel mechanism of resistance to taxanes? . | Biological sciences | Anton Berns, Renee van Amerongen |
| Variation in the epigenetic silencing of FLC contributes to natural variation in Arabidopsis vernalization response.(Report) | Biological sciences | Caroline Dean, Clare Lister, Chikako Shindo, Pedro Crevillen, Magnus Nordborg |
| Wnt/[beta]-catenin signaling regulates vertebrate limb regeneration. | Biological sciences | Yasuhiko Kawakami, Ilir Dubova, Juan Carlos Izpisua Belmonte, Concepcion Rodriguez Esteban, Marina Raya, Hiroko Kawakami, Merce Marti |
| Wnt signaling: Is the party in the nucleus? | Biological sciences | Karl Willert, Kathrine A. Jones |
| X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. | Biological sciences | Asifa Akhtar, Martin J. Lercher, Gaelle Legube, Shannon K. McWeeney |
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