Genes & Development 2007 - Abstracts
| Genes & Development 2007 | |||||
| Title | Subject | Authors | |||
|---|---|---|---|---|---|
| 1abA: A novel gene required for negative feedback regulation of the cyanobacterial circadian clock protein KaiC. | Biological sciences | Yasuhito Taniguchi, Naoki Takai | |||
| Ababidopsis JACKDAW and MAGPIE zinc finger proteins delimit asymmetric cell division and stabilize tissue boundaries by restricting SHORT-ROOT action. | Biological sciences | Renze Heidstra, Ben Scheres, David Welch, Ikram Blilou, Hala Hassan, Richard Immink | |||
| Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104p. | Biological sciences | Thomas Nystrom, Nika Erjavec, Lisa Larsson, Julie Grantham | |||
| A charge-based interaction between histone H4 and Dot1 is required for H3K79 methylation and telomere silencing: Identification of a new trans-histone pathway. | Biological sciences | Ian M. Fingerman, Hui-Chun Li, Scott B. Briggs | |||
| A complex system of small RNAs in the unicellular green alga Chlamydomonas reinhardtii. | Biological sciences | Gregory J. Hannon, Yijun Qi, Tao Zhao, Xiu-Jie Wang, Guanglin Li, Shijun Mi, Shan Li | |||
| A core transcriptional network for early mesoderm development in Drosophila melanogaster. | Biological sciences | Marc Brehme, Thomas Sandmann, Charles Girardot, Waraporn Tongprasit, Viktor Stolc, Eileen E.M. Furlong | |||
| Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis. | Biological sciences | Marc Tessier-Lavigne, Peter Carmeliet, Stephane Germain, Francoise Bono, Monica Autiero, Christian Fischer, Christiane Breant, Anne Eichmann, Li Yuan, Bruno Larrivee, Catarina Freitas, Marc Trombe, Xiang Lv, Benjamin DeLafarge, Karine Bouvree, Raquel Del Toro, Nicolas Brechot, Frederique Dol, Filip Claes, Jean-Leon Thomas | |||
| Adult and larval photoreceptors use different mechanisms to specify the same Rhodopsin fates. | Biological sciences | Claude Desplan, Franck Pichaud, Simon G. Sprecher | |||
| A functional genomic strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock. | Biological sciences | Brigitte Dauwalder, Paul E. Hardin, Kuniaki Takahashi, Akira Matsumoto, Maki Ukai-Tadenuma, Rikuhiro G. Yamada, Jerry Houl, Teiichi Tanimura, Hiroki R. Ueda, Ryu Ueda, Kenichiro D. Uno, Taichi Q. Itoh, Takeya Kasukawa | |||
| A functional study of miR-124 in the developing neural tube. | Biological sciences | Fred H. Gage, Samuel L. Pfaff, Xinwei Cao | |||
| A missed exit: Reelin sets in motion Dab1 polyubiquitination to put the break on neuronal migration. | Biological sciences | Joseph G. Gleeson, Geraldine Kerjan | |||
| A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. | Biological sciences | Jennifer L. Shepard, James F. Amatruda, David Finkelstein, James Ziai | |||
| A new mouse model to explore the initiation, progression, and therapy of [BRAF.sup.V600E]-induced lung tumors.(Clinical report) | Biological sciences | Manuel Serrano, Martin McMahon, Kirk Jones, David Dankort, Elena Filenova, Manuel Collado | |||
| A new role for histone tail modifications in transcription elongation. | Biological sciences | Grant A. Hartzog, John W. Tamkun | |||
| Angiomotin regulates endothelial cell migration during embryonic angiogenesis. | Biological sciences | Lena Claesson-Welsh, Pontus Aspenstrom, Karin Aase, Mira Ernkvist, Lwaki Ebarasi, Lars Jakobsson, Arindam Majumdar, Chunling Yi, Olivier Birot, Yue Ming, Anders Kvanta, Dan Edholm, Joseph Kissil, Akihiko Shimono, Lars Holmgren | |||
| A novel checkpoint mechanism regulating the G1/S transition.(yeast cells) | Biological sciences | Stephen E. Kearsey, Erik Boye, Tonje Jvegard, Hela Soltani, Beata Grallert, Henriette C. Skjolberg, Marit Krohn, Esben A. Nilssen | |||
| A novel class of bacteria-induced small RNAs in Arabidopsis. | Biological sciences | Surekha Katiyar-Agarwal, Shang Gao, Adam Vivian-Smith, Hailing Jin | |||
| A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. | Biological sciences | Gang Lu, Yibin Wang, James Weiss, Shuxudn Ren, Carla Koehler, Paavo Korge, Jau-nian Chen, Jayoung Choi, Yuan Dong | |||
| A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. | Biological sciences | Douglas L. Black, Qin Li, Paul L. Boutz, Geetanjali Chawla, Peter Stoilov, Lily Shiue, Manuel Jr. Ares, Chia-Ho Lin, Kristin Ostrow | |||
| A rap GTPase interactor, RADIL, mediates migration of neural crest precursors. | Biological sciences | A. Thomas Look, Daniel A. Haber, Dennis C. Sgroi, Gromoslaw A. Smolen, Randall T. Peterson, Rodney A. Stewart, Benjamin J. Schott, Sven Diederichs, Beth Muir, Heather L. Provencher | |||
| A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. | Biological sciences | Alan R. Saltiel, Alan Cheng, Jack E. Dixon, Mei Zhang, Matthew S. Gentry, Carolyn A. Worby | |||
| A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. | Biological sciences | Ravi Sachidanandam, Senthil K. Muthuswamy, Ingrid Ibarra, Yaniv Erlich, Gregory Hannon | |||
| A slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. | Biological sciences | Eric A. Miska, Alexander Tarakhovsky, Donal O'Carroll, Ingrid Mecklenbrauker, Partha Pratim Das, Angela Santana, Ulrich Koenig, Anton J. Enright | |||
| A small RNA regulates multiple ABC transporter mRNAs by targeting C/A-rich elements inside and upstream of ribosome-binding sites. | Biological sciences | Fabien Darfeuille, Jorg Vogel, Cynthia M. Sharma, Titia H. Plantinga | |||
| Assembly factors Rpf2 and Rrs1 recruit 5S rRNA and ribosomal proteins rpL5 and rpL11 into nascent ribosomes. | Biological sciences | Jelena Jakovljevic, Marlene Oeffinger, Shawna L. Hiley, Michael P. Rout, Piyanun Harnpicharnchai, Lan Tang, Yurong Guo, Timothy Hughes, John L. Woolford Jr. | |||
| ASY1 mediates AtDMC1-dependent interhomolog recombination during meiosis in Arabidopsis. | Biological sciences | Gareth H. Jones, F. Christopher H. Franklin, Juan-Luis Santos | |||
| A tDNA establishes cohesion of a neighboring silent chromatin domain. | Biological sciences | Marc R. Gartenberg, Rudra N. Dubey | |||
| Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. | Biological sciences | Gabor Juhasz, Balazs Erdi, Miklos Sass, Thomas P. Neufeld | |||
| A three 'helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax. | Biological sciences | Nicholas M. George, Jacquelynn J.D. Evans, Luo Xu | |||
| Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. | Biological sciences | Eileen White, Vassiliki Karantza-Wordsworth, Shyam Patel, Olga Kravchuk, Guanghua Chen, Robin Mathew, Shengkan Jin | |||
| Autophagy: process and function. | Biological sciences | Noboru Mizushima | |||
| Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma. | Biological sciences | Alexander H. Stegh, Hyunggee Kim | |||
| [beta]-catenin induces immortalization of melanocytes by suppressing [p16.sup.INK4a] expression and cooperates with N-Ras in melanoma development. | Biological sciences | Colin R. Goding, Jane Goodall, Suzanne Carreira, Laurence Denat, Lionel Larue, Boris C. Bastian, Friedrich Beermann, Veronique Delmas, Silvia Martinozzi, Julien Ackermann, Mayuko Kumasaka, Flavie Luciani, Amaya Viros, Nese Demirkan | |||
| Bimodal degradation of MLL by [SCF.sup.Skp2] and [APC.sup.Cdc20] assures cell cycle execution: a critical regulatory circuit lost in leukemogenic MLL fusions. | Biological sciences | James J.-D. Hsieh, Han Liu, Emily H.Y. Cheng | |||
| Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase. | Biological sciences | Patrick Sung, Michael G. Sehorn, Peter Chi, Galina V. Petukhova, Joseph San Filippo | |||
| Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. | Biological sciences | Robert Benezra, Sunita Gupta, Vivek Mittal, Daniel J. Nolan, Albert S. Mellick, Jaspreet S. Jaggi, Kathryn Bambino, Alesia Ciarrocchi, Emily Heikamp, Michael R. McDevitt, David A. Sceinberg | |||
| Break on through to the other side: outer membrane penetration of the nascent flagellum by a stop-polymerization mechanism. | Biological sciences | Edgar Huitema, Patrick H. Viollier | |||
| C1pS modulates but is not essential for bacterial N-end rule degradation. | Biological sciences | Robert T. Sauer, Tania A. Baker, Kevin H. Wang | |||
| Canopy shade causes a rapid and transient arrest in leaf development through auxin-induced cytokinin oxidaes activity. | Biological sciences | Giovanna Sessa, Monica Carabelli, Massimiliano Sassi, Andrea Ciolfi, Marco Possenti, Giorgio Morelli, Ida Ruberti | |||
| CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-kappaB activation. | Biological sciences | Chen Dong, Brian C. Grabiner, Marzenna Blonska, Pei-Chun Lin, Yun You, Donghai Wang, Jiyuan Sun, Bryant G. Darnay, Xin Lin | |||
| Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to [G.sub.1].(Clinical report) | Biological sciences | Olaf Nielsen, Soren Kjaerulff, Nicoline Resen Andersen, Mia Trolle Borup | |||
| Cell- and gene-specific regulation of primary target genes by the androgen receptor. | Biological sciences | Keith R. Yamamoto, Hao Li, Eric C. So Bolton Alex Y, Christina Chaivorapol, Christopher M. Haqq | |||
| CHD4/Mi-2beta activity is required for the positioning of the mesoderm/neuroectoderm boundary in Xenopus. | Biological sciences | Elisabeth Kremmer, Tobias Straub, Ralph A.W. Rupp, Britta Linder, Edith Mentele, Katrin Mansperger | |||
| Clockwork orange is a transcriptional repressor and a new Drosophila circadian pacemaker component. | Biological sciences | Michael McDonald, Dan Stoleru, Pipat Nawathean, Sebastian Kadener, Micahel Rosbash | |||
| Control of C. elegans hermaphrodite gonad size and shape by vab-3/Pax-6-mediated regulation of integrin receptors. | Biological sciences | Christopher M. Meighna, Jean E. Schwarzbauer | |||
| Control of sex-specific apoptosis in C. elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho. | Biological sciences | Keiko Gengyo-Ando, Shohei Mitani, Erin Peden, Elizabeth Kimberly, Ding Xue | |||
| Coordinated transcriptional and translational control in metabolic homeostasis in flies.(Clinical report) | Biological sciences | Paul Lasko, Nahum Sonenberg | |||
| Cotranscriptional recruitment of the dosage compensation complex to X-linked target genes. | Biological sciences | Asifa Akhtar, Jop Kind | |||
| Critical roles for Dicer in the female germline. | Biological sciences | Gregory J. Hannon, Richard M. Schultz, Zhenyu Xuan, Michael Q. Zhang, Hua Pan, Elizabeth P. Murchison, Paula Stein | |||
| Cro's role in the CI-Cro bistable switch is critical for [lamda]'s transition from lysogeny to lytic development. | Biological sciences | Ian B. Dodd, J. Barry Egan, Keith E. Shearwin, Rachel A. Schubert | |||
| Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development. | Biological sciences | Libing Feng, Nathaniel S. Allen, Sergi Simo, Joanathan A. Cooper | |||
| Cytokine-dependent imatinib resistance in mouse [BCR-ABL.sup.plus], Arf-null lymphoblastic leukemia.(Report) | Biological sciences | Charles J. Sherr, Richard T. Williams, Willem Besten Den | |||
| Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly. | Biological sciences | Jan A.M. Smeitink, Werner J.H. Koopman, Rutger O. Vogel, Rolf J.R.J. Janssen, Mariel A.M. van den Brand, Cindy E.J. Dieteren, Sjoerd Verkaart, Peter Willems H.G.M., Wendy Pluk, Lambert P.W.J. van den Heuvel, Leo G.J. Nijtmans | |||
| Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator [sigma.sup.s] upon carbon starvation. | Biological sciences | Thomas J. Silhavy, Thomas Nystrom, Asa Fredriksson, Manuel Ballesteros, Celeste N. Peterson, Orjan Persson | |||
| Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.(platelet-derived growth factor)(Clinical report) | Biological sciences | Per Lindblom, Holger Gerhardt, Alexandra Abramsson, Ulf Landegren, Christer Betsholtz, Sindhulakshmi Kurup, Dorothe Spillmann, Marta Busse, Shuhei Yamada, Ulf Lindahl, Edith Schallmeiner, Goran Bondjers, Jin-ping Li Li, Denise Stenzel, Dominique Sauvaget, Johan Ledin, Maria Ringvall, Lena Kjellen | |||
| Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeres. | Biological sciences | Juana M. Flores, Maria A. Blasco, Peter Klatt, Irene Sigel-Cachedenier, Purification Munoz | |||
| Defining the roles of the periplasmic chaperons SurA, Skp, and DegP in Escherichia coli. | Biological sciences | Thomas J. Silhavy, Tao Wu, Daniel Kahne, Joseph G. Sklar | |||
| Design principles of the proteolytic cascade governing the [sigma.sup.E]-mediated envelope stress response in Escherichia coli: Keys to graded, buffered, and rapid signal transduction. | Biological sciences | Rachna Chaba | |||
| Determinants of regulated proteolysis in signal transduction. | Biological sciences | Michael Ehrmann, Sonja Hasenbein, Melisa Merdanovic | |||
| Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/[beta]catenin and Wnt/PCP activities, through interaction with the Dally-like homolog knypek. | Biological sciences | Corinne Houart, Luca Caneparo, Christof Niehrs, Ya-Lin Huang, Nicole Staudt, Masasumi Tada, Reiner Ahrendt, Olga Kazanskaya | |||
| Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression. | Biological sciences | Hartmut Beug, David Engblom, Gunther Schutz, Francois Tronche, Richard Moriggl, Andreas Reimann, Lukas Schwake, Lothar Hennighausen, Jan-Wilhelm Kornfekld | |||
| Discovery of an oncogenic activity in [p27.sup.Kip1] that causes stem cell expansion and a multiple tumor phenotype. | Biological sciences | James M. Roberts, Bruce E. Clurman, Arnaud Besson, Mark Gurian-West, Stacy L. Donovan, Michael A. Dyer, Dianna Johnson, Samantha Cicero, Harry C. Hwang | |||
| Discovery of tMac: a Drosophila testis-specific meiotic arrest complex paralogous to Myb-Muv B. | Biological sciences | Michael R. Botchan, Eileen L. Beall, Maren Bell, Peter W. Lewis, Michael Rocha, D.Leanne Jones | |||
| Dissecting eIF4E action in tumorigenesis. | Biological sciences | Zhu Hong, Scott W. Lowe, Jerry Pelletier, John R. Mills, Rie Watanabe-Fukunaga, Julie Teruya-Feldstein, Hans-Guido Wendel, Abba Malina, Ricardo L.A. Silva, Takeshi Ueda, Rikiro Fukunaga | |||
| Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo. | Biological sciences | Alan G. Hinnebusch, Yuen-Nei Cheung, Julie E. Takacs, Davi Maag, Nikolay Shirokikh, Sarah F. Mitchell, Tatyana Pestova, Christie A. Fekete, Jon R. Lorsch, Mikkel A. Algire | |||
| DNA breaks are masked by multiple Rap1 binding in yeast: Implications for telomere capping and telomerase regulation.(Clinical report) | Biological sciences | David Shore, Alessandro Bianchi, Simona Negrini, Virginie Ribaud | |||
| Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish.(DNA methyltransferase-2)(Clinical report) | Biological sciences | David A. Jones, Bradley R. Cairns, Adam R. Karpf, Kunal Rai, Stephanie Chidester, Chad V. Zavala, Elizabeth J. Manos, Smitha R. James | |||
| Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. | Biological sciences | Rudolf Jaenisch, Yasuhiro Yamada, Alex Meissner, Heinz G. Linhart, Eva Moran, Eveline J. Steine, Sumita Gokhale, Grace Lo, Erika Cantu, Mathias Ehrich, Timothy He | |||
| Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress. | Biological sciences | J. Julian Blow, Dean A. Jackson, Xin Quan Ge | |||
| Drosophila GAGA factor directs histone H3.3 replacement that prevents the heterochromatin spreading. | Biological sciences | Takahiro Nakayama, Susumu Hirose, Kenichi Nishioka, Yi-Xin Dong, Tsukasa Shimojima | |||
| 'Drosophila' PIWI associates with chromatin and interacts directly with HP1a.(Report) | Biological sciences | Li Liu, Ling Jiang, Sarah C.R. Elgin, Brent Brower-Toland, Seth D. Findley, Monica Dus | |||
| Duality of [p27.sup.Kip1] function in tumorigenesis. | Biological sciences | Peter Sicinski, Sima Zacharek, Carla Kim | |||
| Dual role of autophagy in the survival of Caenorhabditis elegans during starvation. | Biological sciences | Leon Avery, Chanhee Kang, Young-jai You | |||
| Dynamic regulation of miRNA expression in ordered stages of cellular development. | Biological sciences | Phillip A. Sharp, Christopher B. Burge, Joel R. Neilson, Grace X.Y. Zheng | |||
| Dynamics and interplay of nuclear architecture, genome organization, and gene expression. | Biological sciences | Robert Schneider, Rudolf Grosschedl | |||
| Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. | Biological sciences | Toshihiko Masui, Mark A. Magnuson, Qiaoming Long, Thomas M. Beres, Raymond J. MacDonald | |||
| Endosomal signaling of plant steroid kinase BRI1. | Biological sciences | Joanne Chory, Karin Schumacher, Niko Geldner, Derek L. Hyman, Xuela Wang | |||
| Enhancing togetherness: Kinetochores and cohesion.(Clinical report) | Biological sciences | Jennifer L. Gerton | |||
| Environmental regulation operating at the promoter clearance step of bacterial transcription. | Biological sciences | Rakesh S. Laishram, Jayaraman Gowrishankar | |||
| Eukaryotic regulatory RNAs: An answer to the 'genome complexity' conundrum. | Biological sciences | David L. Spector, Kannanganattu V. Prasanth | |||
| Evolutionary conservation of cell migration genes: From nematode neurons to vertebrate neural crest. | Biological sciences | Paul W. Sternberg, Marianne Bronner-Fraser, Yun Kee, Byung Joon Hwang | |||
| Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance. | Biological sciences | Raul Andino, Judith Frydman, Marco Vignuzzi, Ron Geller | |||
| Expanding RNA physiology: MicroRNAs in a unicellular organism. | Biological sciences | Haruhiko Siomi, Mikiko C. Siomi | |||
| Expansion of adult [beta]-cell mass in response to increased metabolic demand is dependent on HNF-4[alpha]. | Biological sciences | Klaus H. Kaestner, Peter White, Rana K. Gupta, Kiran Rafiq, Nan Gao, John E. Brestelli, Regina K. Gorski, Guang Chen, Olga T. Hardy, Christian J.Jr. Stoeckert | |||
| Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells. | Biological sciences | Valerie Kouskoff, Wolfgang Breitweiser, Steve Lyons, Ann Marie Flenniken, Garry Ashton, Gail Bruder, Mark Willington, Georges Lacaud, Nie Jones | |||
| FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf. | Biological sciences | Clemens A. Schmitt, Caroline Bouchard, Martin Eilers, Soyoung Lee, Viola Paulus-Hock, Christoph Loddenkemper | |||
| Functional cooperation between HP1 and DNMT1 mediates gene silencing. | Biological sciences | Sriharsa Pradhan, Pierre-Olivier Esteve, Andrea Smallwood, Michael Carey | |||
| Functional interactions between the Moses corepressor and DHR78 nuclear receptor regulate growth in Drosophila.(Middleman of seventy-eight signaling) | Biological sciences | David J. Mangelsdorf, Keith D. Baker, Carl S. Thummel, Robert B. Beckstead | |||
| Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell- surface accumulation. | Biological sciences | Jin Jiang, Jianhang Jia, Lui Yanjuan, Xuesong Cao | |||
| Gas1 extends the range of Hedgehog action by facilitating its signaling. | Biological sciences | David C. Martinelli, Chen-Ming Fan | |||
| Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants. | Biological sciences | Gary Ruvkun, Andrew V. Samuelson, Christopher E. Carr | |||
| Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. | Biological sciences | Barbara J. Graves, Peter C. Hollenhorst, Atul A. Shah, Christopher Hopkins | |||
| Genome-wide view of cell fate specification: ladybird acts as multiple levels during diversification of muscle and heart precursors. | Biological sciences | Krzysztof Jagla, Guillaume Junion, Laetitia Bataille, Teresa Jagla, Jean Philippe Da Ponte, Romain Tapin | |||
| Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb-MuvB/dREAM complex in proliferating cells. | Biological sciences | Michael R. Botchan, Eileen L. Beall, Daphne Georlette, David M. MacAlpine, Stephen P. Bell, Peter W. Lewis, Soyeon Ahn, Evelyn Cheung, Terry Speed, J. Robert Manak | |||
| Getting connected: Analysis and principles of biological networks. | Biological sciences | Michael Snyder, Mark Gerstein, Xiaowei Zhu | |||
| Global analysis of alternative splicing differences between humans and chimpanzees. | Biological sciences | Benjamin J. Blencowe, Christopher Lee, Mario Caceres, John A. Calarco, Yi Xing, Joseph P. Calarco, Xinshu Xiao, Qun Pan, Todd M. Preuss | |||
| Gravin regulates mesodermal cell behavior changes required for axis elongation during zebrafish gastrulation. | Biological sciences | David Kimelman, Douglas C. Weiser, Ujawal J. Pyati | |||
| H2B ubiquitylation in transcriptional control: A fact-finding mission. | Biological sciences | Brian D. Strahl, R. Nicholas Laribee, Stephen M. Fuchs | |||
| HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates. | Biological sciences | Tso-Pang Yao, Cecile Caron, Saadi Khochbin, Cyril Boyault, Yu Zhang, Sabrina Fritah, Benoit Gilquin, So Hee Kwan, Carmen Garrido, Claire VourcEh, Patrick Matthias | |||
| Hematopoietic reconstitution with androgenetic and gynogenetic stem cells. | Biological sciences | Kevin D. Bunting, Sigrid Eckardt, N. Adrian Leu, Heath L. Bradley, Hiromi Kato, K. John McLaughlin | |||
| Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria. | Biological sciences | J. I-Ju Leu, Donna L. George | |||
| Hippo signaling in organ size control. | Biological sciences | Duojia Pan | |||
| Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. | Biological sciences | James A. Richardson, Eric N. Olson, Joseph A. Hill, Xiaoxia Qi, Rusty L. Montgomery, Michael Haberland, Jens Fielitz, Christopher A. Davis, Matthew J. Potthoff | |||
| HLA-B-associated transcript 3 (Bat3)/scythe is essential for p300-mediated acetylation of p53.(human leukocyte antigen complex, class I, B)(major histocompatibility complex, class I, B) | Biological sciences | Andrew Wakeham, Tak W. Mak, Hitoshi Okada, Sally Kornbluth, Toru Sasaki, Eugene C. Gan | |||
| Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing. | Biological sciences | Oleg N. Voloshin, Roberto Pezza, Filip Vanevski, R.Daniel Camerini-Otero | |||
| Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality control. | Biological sciences | Kathleen Collins, J. Robert Hogg | |||
| Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. | Biological sciences | Bin Zhao, Kun-Liang Guan, Li Li, Zhi-Chun Lai, Xiaomu Wei, Qian Yang, Jindan Yu, Weiquan Li, Ryan S. Udan, Joungmok Kim, Joe Xie, Ikenoue Tsuneo, Pan Zheng, Keqiang Ye, Arul Chinnaiyan, Georg Halder | |||
| In a tight spot: ARE-mRNAs at processing bodies. | Biological sciences | Georg Stoecklin, Paul Anderson | |||
| Increased association of telomerase with short telomerase in yeast. | Biological sciences | David Shore, Alessandro Bianchi | |||
| Independent and interdependent functions of LAF1 and HFR1 in phytochrome A signaling. | Biological sciences | Nam-Hai Chua, In-Cheol Jang, Jun-Yi Yang, Seong Wook Yang | |||
| Inhibition of U snRNP assembly by a virus-encoded proteinase.(Clinical report) | Biological sciences | Peter Sarnow, Laura L. Almstead | |||
| Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm. | Biological sciences | Pierre A. Coulombe, Seyun Kim | |||
| Intersubunit signaling in RecBCD enzyme, a complex protein machine regulated by Chi hot spots. | Biological sciences | Gerald R. Smith, Susan K. Amundsen, Andrew F. Taylor, Manjula Reddy | |||
| Introns play an essential role in splicing-dependent formation of the exon junction complex. | Biological sciences | Masatoshi Hagiwara, Takashi Ideue, Yasnory T.F. Sasaki, Tetsuro Hirose | |||
| Ipl 1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores. | Biological sciences | Nick Morrice, Najma Rachidi, Emma M.J. King, Kevin G. Hardwick, Michael J.R. Stark | |||
| IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback. | Biological sciences | Robert Tjian, Oscar Puig, Michael T. Marr II, Joseph A. D'Alessio | |||
| ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP.(interferon stimulated gene)(eukaryotic initiation factor)(Clinical report) | Biological sciences | Dong-Er Zhang, Fumihiko Okumura, Weiguo Zon | |||
| Jmjd1a and jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. | Biological sciences | Xi Chen, Huck-Hui Ng, Yuin-Han Loh, Weiwei Zhang, Joshy George | |||
| Kinetochore-microtubule interaction during S phase in Saccharomyces cerevisiae. | Biological sciences | Kozo Tanaka, Etsushi Kitamura, Yoko Kitamura, Tomoyuki U. Tanaka | |||
| Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system. | Biological sciences | Shigeyuki Yokoyama, Osamu Ohara, Motoaki Wakiyama, Koji Takimoto | |||
| Life beyond cleavage: The case of Ago2 and hematopoiesis. | Biological sciences | Meinrad Busslinger, Javier Martinez | |||
| Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency. | Biological sciences | Annick Harel-Bellan, Anna Polesskaya, Sylvain Cuvellier, Irina Naguibneva, Arnaud Duquet, Eric G. Moss | |||
| Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. | Biological sciences | Oleg V. Lagutin, Guillermo Oliver, Fu-Jung Lin, Ming-Jer Tsai, Igor M. Samokhvalov, R. Sathish Srinivasan, Miriam E. Dillard, Sophia Tsai | |||
| Linking the hematopoietic microenvironment to imatinib-resistant P[h.sup.+] B-ALL. | Biological sciences | Owen N. Witte, Kenneth Dorshking | |||
| Long-range action of Nodal requires interaction with GDF1. | Biological sciences | Yukio Saijoh, Hiroshi Hamada, Chinatsu Tanaka, Rui Sakuma, Tetsuya Nakamura | |||
| Lung premalignancy induced by mutant B-Raf, what is thy fate? To senesce or not to senesce, that is the question.(Clinical report) | Biological sciences | Kevin M. Haigis, Ignacio I. Wistuba, Jonathan M. Kurie | |||
| Mad3p, a pseudosubstrate inhibitor of [APC.sup.cdc20] in the spindle assembly checkpoint. | Biological sciences | Janet L. Burton, Mark J. Solomon | |||
| Malignant astrotyic glioma: genetics, biology, and paths to treatment. | Biological sciences | David N. Louis, Ronald A. DePinho, Lynda Chin, William C. Hahn, Frank B. Furnari, Robert M. Bachoo, Webster K. Cavenee, Keith L. Ligon, Tim Fenton, Akitake Mukasa, Jayne M. Stommel, Alexander Stegh, Brennan, Cameron; | |||
| Maternal microRNAs are essential for mouse zygotic development. | Biological sciences | Sheila C. Barton, M. Azim Surani, Alexander Tarakhovsky, Donal O'Carroll, Masahiro Kaneda, Fuchou Tang, Andrew Y. Sun, Caroline Lee, Petra Hajkova, Kaiqin Lao | |||
| Maternal PPAR [gamma] protects nursing neonates by suppressing the production of inflammatory milk.(Clinical report) | Biological sciences | Ronald M. Evans, Alan Saghatelian, Chun-Li Zhang, Yihong Wan, Ling- Wa Chong, Benjamin. F. Cravatt | |||
| Mcm10 and And-1/CTF4 recruit DNA polymerase [alpha] to chromatim for initiation of DNA replication.(Report) | Biological sciences | James A. Wohlschlegel, Anindya Dutta, Leta K. Nutt, Sally Kornbluth, Wenge Zhu, Chinweike Ukomadu, Sudhakar Jha, Senga Takeshi, Suman K. Dhar | |||
| Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation and termination factor eRF3 and mRNA deadenylases. | Biological sciences | Ichio Shimada, Tsutomu Suzuki, Yuji Funakoshi, Yusuke Doi, Nao Hosoda, Naoyuki Uchida, Masanori Osawa, Masafumi Tsujimoto, Toshiaki Katada, Shin-ichi Hoshino | |||
| Mechanism of mRNA destabilization by the glmS ribozyme. | Biological sciences | Wade C. Winkler, Jennifer A. Collins, Irnov Irnov, Stephanie Baker | |||
| Mechanisms of obesity-related insulin resistance: Many choices on the menu. | Biological sciences | Mitchell A. Lazar, Mohammed Qatanani | |||
| Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway.(nonsense-mediated mRNA decay) | Biological sciences | Ronald H. A. Plasterk, Dasa Longman, Iain L. Johnstone, Javier P. Caceres | |||
| Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell protein. | Biological sciences | Michael L. Cleary, Tim C.P. Somervaille, Piu Wong, Masayuki Iwasaki, Chai Whai Wai Eric So | |||
| MicroRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in 'Drosophila'.(Report) | Biological sciences | Stephen M. Cohen, Jishy Varghese | |||
| MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. | Biological sciences | Douglas L. Black, Paul L. Boutz, Geetanjali Chawla, Peter Stoilov | |||
| MicroRNAs repress translation of [m.sup.7] Gppp-capped target mRNAs in vitro by inhibiting initiation and promoting deadenylation. | Biological sciences | Nancy Standart, Richard J. Jackson | |||
| Microtubule-induced cortical cell polarity. | Biological sciences | Chris Q. Doe, Sarah E. Siergrist | |||
| Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA. | Biological sciences | Josef Jiricny, Massimo Lopes, Nina Mojas | |||
| Modeling complex genetic interactions in a simple eukaryotic genome: Actin displays a rich spectrum of complex haploinsufficiencies. | Biological sciences | Brian Haarer, Susan Viggiano, Mathew A. Hibbs, Olga G. Troyanskaya, David C. Amberg | |||
| Molecular regulation of visual system development: More than meets the eye.(Clinical report) | Biological sciences | Chikako Harada, Takayuki Harada, Luis F. Farada | |||
| Motif module map reveals enforcement of aging by continual NF-[kappa]B activity. | Biological sciences | Howard Y. Chang, Jennifer Y. Zhang, Saurabh Sinha, Eran Segal, Adam S. Adler, Tiara L.A. Kawahara | |||
| Multiple small RNAs act additively to integrate sensory information and control quorum sensing in Vibrio harveyi. | Biological sciences | Bonnie L. Bassler, Kimberly C. Tu | |||
| Multipotent hematopoietic cells susceptible to alternative double-strand break repair pathways that promote genome rearrangements.(Clinical report) | Biological sciences | Christine Richardson, Richard Francis | |||
| Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling and inhibits apoptosis in thymocytes. | Biological sciences | Eric Verdin, Tokameh Mahmoudi, Maribel Parra | |||
| NBK/BIK antagonizes MCL-1 and BCL-[X.sub.L] and activates BAK-mediated apoptosis in response to protein synthesis inhibition. | Biological sciences | Eileen White, Masayori Inouye, Kurt Degenhardt, Tsutomu Shimazu, Alam Nur-E-Kamal, Junjie Zhang, Takeshi Yoshida, Yonglong Zhang, Robin Mathew | |||
| N-cofilin is associate with neuronal migration disorders and cell cycle control in the cerebral cortex.(Report) | Biological sciences | Gian Bellenchi Carlo, Christine B Gurniak, Emerald Perlas, Silvia Middei, Martine Ammassari-Teule, Walter Witke | |||
| Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells. | Biological sciences | Richard I. Morimoto, Susana M. Garcia, M. Olivia Casanueva, M. Catarina Silva, Margarida D. Amaral | |||
| New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis. | Biological sciences | John J. Mekalanos, Michael Snyder, Mark Gerstein, Michael G. Smith, Tara A. Gianoulis, Stefan Pukatzki, Nicholas L. Ornston | |||
| Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCK[alpha] kinases. | Biological sciences | Daniel Hohl, Vikram Devgan, Karine Lefort, Anna Mandinova, Giovanna Chiorino, Paola Ostano, Vihren Kolev, Valerie Calpini, Ingrid Kolfschoten, Jocelyn Lieb, Wassim Raffoul, Victor Neel, Jonathan Garlick, Paolo Dotto G. | |||
| Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. | Biological sciences | Edward H. Egelman, Alexander V. Mazin, Dmitry V. Bugreev, Xiong Yu | |||
| Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome.(Report) | Biological sciences | Beate Schwer, Anna Aronova | |||
| Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA replication. | Biological sciences | Craig H. Bassing, J. Alan Diehl, Beth Nuskey, Anil K. Rustgi, Mariusz A. Wasik, Priya Aggarwal, Matthew D. Lessie, Douglas I. Lin, Laura Pontano, Andrew B. Gladden, Ami Goradia, Andres J.P. Klein-Szanto | |||
| Nuclear receptor ERR[alpha] and coactivator PGC-1[beta] are effectors of IFN- [gamma] induced host defence. | Biological sciences | Ronald M. Evans, Junichiro Sonoda, Vincent Giguere, Chih-Hao Lee, Immo E. Scheffler, Ling- Wa Chong, Josee Laganiere, Isaac R. Mehl, Grant D. Barish, Xiangli Li, Dennis C. Mock, Alain R. Battille, Francisco Robert | |||
| Nucleosome stability mediated by histone variants H3.3and H2A.Z . | Biological sciences | Gary Felsenfeld, Chunyuan Jin | |||
| On a roll for new TRF targets.(TATA-box-binding-protein related factor) | Biological sciences | Nouria Hernandez, Jaime H. Reina | |||
| Oncogene addiction: setting the stage for molecularly targeted cancer therapy. | Biological sciences | Jeffrey Settleman, Sreenath V. Sharma | |||
| Oncogenes and senescence: Breaking down in the fast lane. | Biological sciences | Michael T. Hemann, Masashi Narita | |||
| Oncogenic HMGA2: Short or small?(High Mobility Group A 2) | Biological sciences | Masashi Narita, Andrew R. J. Young | |||
| Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. | Biological sciences | Brooke Ancrile, Kian-Huat Lim, Christopher M. Counter | |||
| Open conformation chromatin and pluripotency. | Biological sciences | Hitoshi Niwa | |||
| Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading. | Biological sciences | Stephen P. Bell, Shuyan Chen, Milan A. de Vries | |||
| P21 transcription is regulated by differential localization of histone H2A.Z. | Biological sciences | David M. Livingston, Ho Man Chan, Nicholas Gevry, Liette Laflamme, Luc Gaudreau | |||
| PGC-1[alpha] regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy. | Biological sciences | Bruce M. Spiegelman, Patrick Seale, Kevin P. Campbell, Christoph Handschin, Yvonne M. Kobayashi, Sherry Chin | |||
| Pharmacologic disruption of polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.(Clinical report) | Biological sciences | Wei Chen, Edison T. Liu, Qiang Yu, Xiaojing Yang, Jing Tan, Li Zhuang, Xia jiang, Puay Leng Lee, R. K. Murthy Karuturi, Patrick Boon Ooi Tan | |||
| Phosphorylation of histone H3 at Ser10 facilitates RNA polymerase II release from promoter-proximal pausing in Drosophila. | Biological sciences | Victor G. Corces, M. Soledad Ivaldi, Caline S. Karam | |||
| Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi-interacting RNAs at their 3' ends. | Biological sciences | Haruhiko Siomi, Mikiko C. Siomi, Tsutomu Suzuki, Kuniaki Saito, Yuriko Sakaguchi, Takeo Suzuki | |||
| Pin1 modulates RNA polymerase II activity during the transcription cycle. | Biological sciences | James L. Manley, Yu-Xin Xu | |||
| piRNAs- the ancient hunters of genome invaders. | Biological sciences | Yukihide Tomari, Julia Verena Hartig, Klaus Forstemann | |||
| Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. | Biological sciences | Yuh Nung Jan, Lily Yeh Jan, Jay Z. Parrish, Kazuo Emoto | |||
| Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion. | Biological sciences | Jorg Grobhans, Robert Grosse, Oliver T. Fackler, Thomas M. Kitzing, Arul S. Sahadevan, Dominique T. Brandt, Helga Knieling, Sebastian Hannemann | |||
| Post-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1). | Biological sciences | Amita Sehgal, Sriram Sathyanarayanan, Yanshan Fang | |||
| pRB family proteins are required for H3K27 trimethylation and polycomb repression complexes binding to and silencing [p16.sup.INK4a] tumor suppressor gene. | Biological sciences | Julien Sage, Yi Zhang, Yue Xiong, Yojiro Kotake, Patrick Viatour | |||
| Presynaptic establishment of the synaptic cleft extracellular matrix is required for post-synaptic differentiation. | Biological sciences | Kendal Broadie, Jeffrey Rohrbough, Emma Rushton, Elvin Woodruff III, Tim Fergestad, Krishanthan Vigneswaran | |||
| PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation. | Biological sciences | Claudia Stein, Uta-Maria Bauer, Emile Schiltz, Dawin Hyllus, Kristin Schnabel, Axel Imhof, Yali Dou, James Hsieh | |||
| Protein kinase A and casein kinases mediate sequential phosphorylation events in the circadian negative feedback loop. | Biological sciences | Yi Liu, Qiyang He, Joonseok Cha, She Chen, Guocun Huang, Shaojie Li, Chengzu Long, Lily Li | |||
| PTB/nPTB switch: A post-transcriptional mechanism for programming neuronal differentiation. | Biological sciences | Yi Zhang, Xiang-Dong Fu, Gabriela C. Coutinho-Mansfield, Yuanchao Xue | |||
| QIP, a putative exonuclease, interacts with the Neurospora Argonaute protein and facilitates conversion of duplex siRNA into single strands. | Biological sciences | Yi Liu, Heng-Chi Lee, Mekhala Maiti | |||
| Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function. | Biological sciences | Lynne E. Maquat, Olaf Isken | |||
| Rational design of memory in eukaryotic cells.(Report) | Biological sciences | Pamela A. Silver, David A. Drubin, Julian A. Eskin, Caroline M. Ajo-Franklin, Elaine P.S. Gee, Dirk Landgraf, Ira Phillips | |||
| Rb is critical in a mammalian tissue stem cell population. | Biological sciences | Pamela L. Wenzel, Lizhao Wu, Alain de Bruin, Jean-Leon Chong, Wen-Yi Chen | |||
| RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.(Clinical report) | Biological sciences | Paul A. Trainor, Lisa L. Sandell, Brian W. Sanderson, Gennadiy Moiseyev, Teri Johnson, Aready Musheigan, Kendra Young, Jean-Philippe Rey, Jian-xing Ma, Staehling-Hampton. Karen | |||
| Rearrangement of competing U2 RNA helices within the spliceosome promotes multiple steps in splicing. | Biological sciences | Rhonda J. Perriman, Manuel Jr. Ares | |||
| RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination. | Biological sciences | Marco Foiani, Dana Branzei | |||
| RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. | Biological sciences | Maria Jasin, Patrick Sung, Wendy Bussen, Michael G. Sehorn, Hannes Vogel, Yiduo Hu, Steven Raynard, Xincheng Lu, Jeremy M. Stark, Ellen L. Barnes, Peter Chi, Pavel Janscak, Guangbin Luo | |||
| Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells. | Biological sciences | Brian McStay, Jose-Luis Preito | |||
| Re-evaluating AKT regulation: Role of TOR complex 2 in tissue growth.(target of rapamycin) | Biological sciences | Ville Hietakangas, Stephen M Cohen | |||
| Regulation of plant innate immunity by three proteins in a complex conserved across the plant and animal kingdoms. | Biological sciences | Xin Li, Wei Cheng, Kristoffer Palma, Qinggao Zhao, Yu Ti Cheng, Dongling Bi, Jacqueline Monaghan, Yeulin Zhang | |||
| Regulation of the [sigma]E stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress. | Biological sciences | Michael Ehrmann, Corinna Wilken, Robert Kurzbauer, Tim Clausen, Sonja Hasenbein, Hanna Hasselblatt, Tobias Krojer, Justyna Sawa, Juliane Kurt, Rebecca Kirk | |||
| Regulation of vascular morphogenesis by Notch signaling. | Biological sciences | Ralf H. Adams, Cristina Roca | |||
| Reinduction of ErbB2 in astrocytes promotes radial glial progenitor identity in adult cerebral cortex. | Biological sciences | H.T. Ghashghaei, Jill M. Weimer, Ralf S. Schmid, Yukako Yokota, Ken D. McCarthy, Brian Popko, E.S. Anton | |||
| Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components. | Biological sciences | Richard Cooke, Dominique Pontier, Mohamed-Ali Hakimi, Danielle Vega, Thierry Lagrange, Steven E. Jacobsen, Mahmoud El-Shami, Sylvie Lahmy, Laurence Braun, Claire Picart | |||
| Replication fork stalling and cell cycle arrest in UV-irradiated Escherichia coli. | Biological sciences | Robert G. Lloyd, Christian J. Rudolph, Amy L. Upton | |||
| Requirement of JIP scaffold proteins for NMDA-mediated signal transduction.(N-methyl-D-aspartic acid)(Report) | Biological sciences | Roger J. Davis, Richard A. Flavell, Norman J. Kennedy, Pasko Rakic, Gilles Martin, Anka G. Ehrhardt, Julie Cavanagh-Kyros, Steven N. Treistman | |||
| Rethinking the proximodistal axis of the vertebrate limb in the molecular era. | Biological sciences | Lewis Wolpert, Cliff Tabin | |||
| Retrosequence formation restructures the yeast genome. | Biological sciences | Patrick H. Maxwell, M. Joan Curcio | |||
| RGS 10-null mutation impairs osteoclast differentiation resulting from the loss of [Ca.sup.2+ .sub.i] . | Biological sciences | Shuying Yang, Yi-Ping Li | |||
| Rho deep in thought.(role of Rho in brain workings) | Biological sciences | Rachel McMullan, Stephen J. Nurrish | |||
| Rhythmic control of AANAT translation by hnRNP Q in circadian melatonin production. | Biological sciences | Tae-Don Kim, Kyong-Tai Kim, Kyung-Chul Woo, Sunghan Cho, Dae-Cheong Ha, Sung Key Jang | |||
| Riboswitch-dependent gene regulation and its evolution in the plant kingdom. | Biological sciences | Evgeny Nudler, Michal Shapira, Samuel Bocobza, Avital Adato, Tali Mandel, Asaph Aharoni | |||
| RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB. | Biological sciences | Joel D. Richter, Jong Heon Kim | |||
| RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. | Biological sciences | C. David Allis, Donald F. Hunt, Yifan Liu, Jeffery Shabanowitz, Sean D. Taverna, Tara L. Muratore | |||
| Role of SVP in the control of flowering time by ambient temperature in Arabidopsis.(Short Vegetative Phase) | Biological sciences | Jong Seob Lee, Seong Jeon Yoo, Soo Hyun Park, Ildoo Hwang, Ji Hoon Ahn | |||
| Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres. | Biological sciences | Silke Hauf, Yoshinori Watanabe, Tomoya S. Kitajima, Shigehiro A. Kawashima, Tatsuya Tsukahara, Maria Langegger | |||
| Signaling form plant endosomes: Compartments with something to say!. | Biological sciences | Natasha Raikhel, Glenn Hicks | |||
| Silencing of the xenogeneic DNA by H-NS-facilitation of lateral gene transfer in bacteria by a defense system that recognizes foreign DNA. | Biological sciences | Ferric C. Fang, Michael McClelland, William Wiley Navarre, Stephen J. Libby | |||
| Single- and double-stranded DNA: Building a trigger of ATR-mediated DNA damage response. | Biological sciences | Lee Zou | |||
| Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins. | Biological sciences | Hong Liang, Zhixiong Xu, Xianzhang Meng, Ying Cai, Lalitha Nagarajan, Stephen J. Brandt | |||
| SIRT1 controls endothelial angiogenic functions during vascular growth. | Biological sciences | Frederick W. Alt, Raul Mostoslavsky, Stefanie Dimmeler, Andreas M. Zeiher, Elisabetta Dejana, Michael Potente, Laleh Ghaeni, Danila Baldessari, Lothar Rossig, Franck Dequiedt, Judith Haendeler, Marina Mione | |||
| SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. | Biological sciences | Danny Reinberg, Alejandro Vaquero, Michael B. Scher | |||
| Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis. | Biological sciences | Tyler Jacks, Roderick T. Bronson, Denise Crowley, David A. Tuveson, Rudolf Jaenisch, James R. Stone, Alexander Meissner, Alice T. Shaw, James A. Dowdle, Margaret Magendantz, Chensi Ouyang, Tiziana Parisi, Jayaraj Rajagopal, Leah J. Blank | |||
| Strength in numbers: Preventing rereplication via multiple mechanisms in eukaryotic cells. | Biological sciences | Johannes C. Walter, Emily E. Arias | |||
| Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. | Biological sciences | Xin Liu, Ronen Marmorstein | |||
| SWI/SNF is required for transcriptional memory at the yeast GAL gene cluster. | Biological sciences | Craig L. Peterson, Sharmistha Kundu, Peter J. Horn | |||
| Switching of the core transcription machinery during myogenesis. | Biological sciences | Robert Tjian, Maria Divina E. Deato | |||
| Targeting oncogenic Ras. | Biological sciences | Ernesto Diaz-Flores, Kevin Shannon | |||
| Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. | Biological sciences | Peer Bork, Elisa Izaurralde, Michael Boutros, Jan Rehwinkel, Tobias Doerks, Ana Eulalio, Mona Stricker, Eric Huntzinger, Silke Dorner | |||
| Tbx3 controls the sinoartrial node gene program and imposes pacemaker function on the atria. | Biological sciences | Phil Barnett, Janynke F. Brons, Vincent M. Christoffels, Willem M. H. Hoogaars, Angela Engel, Arie O. Verkerk, Frederik J. de Lange, L .Y. Elaine Wong, Martijn L. Bakker, Danielle E. Clout, Vincent Wakker, Jan Hindrik Ravesloot, Antoon F. M. Moorman, E. Etienne Verheijck | |||
| Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis. | Biological sciences | Juana M. Flores, Purificacion Munoz, Peter Klatt, Raquel Blanco, Maria A. Blasen | |||
| Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae. | Biological sciences | Milica Arneric, Joachim Lingner, Michael Chang | |||
| Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network. | Biological sciences | Peter Carlsson, Thomas Sandmann, Eileen E.M. Furlong, Janus S. Jakobsen, Martina Braun, Jeanette Astorga, E. Hilary Gustafson, Michal Karzynski | |||
| Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore-microtubule interactions. | Biological sciences | Erich A. Nigg, Sabine Elowe, Stefan Hummer, Andreas Uldschmid, Xiuling Li | |||
| TGF-[beta] signaling-mediated morphogenesis: Modulation of cell adhesion via cadherin endocytosis. | Biological sciences | Naoto Ueno, Christof Niehrs, Souchi Ogata, Ken W.Y.Cho, Junji Morokuma, Tadayoshi Hayata, Gabriel Kolle | |||
| The A, B, Gs of silencing. | Biological sciences | Ali Shilatifard, Edwin Smith | |||
| The APC/C inhibitor, Emil, is essential for prevention of rereplication. | Biological sciences | Anindya Dutta, Yuichi J. Machida | |||
| The band mutation in Neurospora crassa is a dominant allele of ras-1 implicating RAS signaling in circadian output. | Biological sciences | Jennifer J. Loros, Jay C. Dunlap, Luis F. Larrondo, William J. Belden, Allan C. Froelich, Mi Shi, Chen-Hui Chen | |||
| The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9. | Biological sciences | H. Robert Horvitz, Hillel T. Schwartz | |||
| The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response. | Biological sciences | Yu Zhang, Patrick Matthias, SoHee Kwon | |||
| The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. | Biological sciences | Gerardo Ferbeyre, Frederick A. Mallette, Marie-France Gaumont-Leclerc | |||
| The enhancement of pericentromeric cohesion association by conserved kinetochore components promotes high-fidelity chromosome segregation and is sensitive to microtubule-based tension.(Clinical report) | Biological sciences | Paul C. Megee, Carrie A. Eckert, Daniel J. Gravdahl | |||
| The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. | Biological sciences | Wafik S. El-Deiry, Hiroshi Nakagawa, Meenhard Herlyn, Andres J. Klein-Szanto, Anil K. Rustgi, Takaomi Okawa, Carmen Z. Michaylira, Jiri Kalabis, Douglas B. Stairs, Claudia D. Andl, Cameron N. Johnstone, Edna Cukierman | |||
| The Hedgehog-binding proteins Gas 1 and Cdo cooperate to positively regulate Shh signaling during mouse development. | Biological sciences | Andrew P. McMahon, Toyoaki Tenzen, Benjamin L. Allen | |||
| The hematopoietic stem cell and its niche: a comparative view. | Biological sciences | Utpal Banerjee, Volker Hartenstein, Julian A. Martinez-Agosto, Hanna K.A. Mikkola | |||
| The interaction of DiaA and DnaA regulates the replication cycle in E.coli by directly promoting ATP-DnaA-specific initiation complexes. | Biological sciences | Shigeyuki Yokoyama, Kenji Keyamura, Fujikawa Norie, Takuma Ishida, Shogo Ozaki, Masayuki Su'etsugu, Kazuyuki Fujimitsu, Wataru Kagawa, Hitoshi Kurumizaka, Tsutomu Katayama | |||
| The lateral line microcosmos. | Biological sciences | Christine Dambly-Chaudiere, Alain Ghysen | |||
| The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation. | Biological sciences | Ann Kaminski, Richard J. Jackson, Tuija A.A. Poyry, Emma J. Connell, Christopher S. Fraser | |||
| The mechanism of outer membrane penetration by the eubacterial flagellum and implications for spirochete evolution.(Report) | Biological sciences | Joyce E. Karlinsey, Kelly T. Hughes, Noriko Takahashi, Fabienne F.V. Chevance, Joshua Gnerer, Takanori Hirano, Ram Samudrala | |||
| The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. | Biological sciences | Bora Lee, Jaya Visvanathan, Seunghee Lee, Jae W.Lee, Soo-kyung Lee | |||
| The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron. | Biological sciences | Donald G. Moerman, Oliver Hobert, Robert A. Holt, Marco A. Marra, John F. Etchberger, Adam Lorch, Monica C. Sleumer, Richard Zapf, Steven J. Jones | |||
| The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination. | Biological sciences | James L. Manley, Matthew Meyerson, Syuzo Kaneko, Orit Rozenblatt-Rosen | |||
| The nature of telomere fusion and a definition of the critical telomere length in human cells. | Biological sciences | Rebecca Capper, Bethan Britt-Compton, Maira Tankimanova, Jan Rowson, Boitelo Letsolo, Stephen Man, Michele Haughton, Duncan M. Baird | |||
| The neurohormone orexin stimulates hypoxia-inducible factor-1 activity. | Biological sciences | Thomas Kodadek, Devanjan Sikder | |||
| The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer.(Report) | Biological sciences | Douglas Hanahan, Erwin F. Wagner, Richard D. Palmiter | |||
| The PAS/ LOV protein VIVID controls temperature compensation of circadian clock phase and development in Neurospora crassa. | Biological sciences | Christian Heintzen, Mark Elvin, Suzzane M. Hunt, Susan Croswaite | |||
| The polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. | Biological sciences | Jean-Christophe Marine, Kristian Helin, Adrian P. Bracken, Bo T. Porse, Nikolaj Dietrich, Diego Pasini, Klaus H. Hansen, Daniela Kleine-Kohlbrecher, Gaetano Gargiulo, Chantal Beekman, Kim Theilgaard-Monch, Saverio Munucci | |||
| The prepattern transcription factor Irx3 directs nephron segment identity.(Report) | Biological sciences | Andreas Kispert, Luca Reggiani, Daniela Raciti, Rannar Airik, Andre W. Brandli | |||
| The Prp18 protein stabilizes the interaction of both exons with the U5 snRNA during the second step of pre-mRNA splicing. | Biological sciences | Luciana B. Crotti, Dagmar Bacikova, David S. Horowitz | |||
| The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. | Biological sciences | Sinny Delacroix, Jill M. Wagner, Masahiko Kobayashi, Ken-ichi Yamamoto, Larry M. Karnitz | |||
| The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons. | Biological sciences | Aaron DiAntonio, Joshua R. Sanes, A. Joseph Bloom, Bradley R. Miller | |||
| The role of the proteasomal ATPases and activator monoubiquitylation in regulating Ga14 binding to promoters. | Biological sciences | Devanjan Sikder, Anwarul Ferdous | |||
| The secretory peptide gene EPF1 enforces the stomatal one-cell-spacing rule. | Biological sciences | Tatsuo Kakimoto, Keiko U. Torii, Dominique C. Bergmann, Kenta Hara, Ryoko Kajita | |||
| The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice.(Clinical report) | Biological sciences | Jean-Marc A. Lobaccaro, Johan Auwerx, Sander M. Houten, Carolyn L. Cummins, David H. Volle, Rajesha Duggavathi, Benjamin C. Magnier, Guido Verhoeven, Kristina Schoonjas | |||
| The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. | Biological sciences | Ronald M. Evans, Katherine A. Jones, Loni Pickle, Sunnie M. Yoh, Helen Cho | |||
| The structural determinants of checkpoint activation. | Biological sciences | Tony S. Byun, Muh-ching Yee, Karlene A. Cimprich, Christina A. MacDougall, Christopher Van | |||
| The t-complex-encoded guanine nucleotide exchange factor Fgd2 reveals that two opposing signaling pathways promote transmission ratio distortion the mouse. | Biological sciences | Bernhard G. Herrmann, Hermann Bauer, Nathalie Veron, Jurgen Willert | |||
| The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription. | Biological sciences | James Douglas Engel, Masayuki Yamamoto, Qinghui Liu, Osamu Tanabe, Yannan Shen, Andrew D. Campbell, Takashi Kuroha | |||
| The transcription factor HIF-1[alpha] plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. | Biological sciences | M. Celeste Simon, Craig B. Thompson, Julian J. Lum, Kelly L. Covello, John D. Gordan, Thi Bui, Michaela Gruber, Ralph J. DeBerardinis | |||
| The trithorax group protein lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. | Biological sciences | Ling Li, Robert N. Eisenman, Julie Secombe, Leni Carlos | |||
| The tumor suppressor microRNA let-7 represses the HMGA2 oncogene.(Clinical report) | Biological sciences | Anindya Dutta, Yong Sun Lee | |||
| Top1- and Top2- mediated topological transitions at the replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation. | Biological sciences | Marco Foiani, Hirokazu Tanaka, Katsuhiko Shirahige, Rodrigo Bermejo, Ylli Doksani, Thelma Capra, Yuki- Mori Katou | |||
| Transcription elongation controls cell fate specification in the Drosophila embryo. | Biological sciences | Xiaoling Wang, Chanhyo Lee, David S. Gilmour, J. Peter Gergen | |||
| Transcription of histone gene cluster by differential core-promoter factors. | Biological sciences | Andreas Hochheimer, Matthias Prestel, Yoh Isogai, Sunduz Keles, Robert Tijian | |||
| Transcription strategies in terminally differentiated cells: shaken to the core. | Biological sciences | Katherine A. Jones | |||
| Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression. | Biological sciences | David S. Gilmour, Zhiqiang Zhang, Alicia Klatt, Andrew J. Henderson | |||
| Translation of the poly(A) tail plays crucial roles in nonstop mRNA surveillance via translation repression and protein destabilization by proteasome in yeast. | Biological sciences | Toshifumi Inada, Sayoko Ito-Harashima, Kazushige Kuroha Kuroha, Tsuyako Tatematsu | |||
| Trio's Rho-specific GEF domain is the missing G[[alpha].sub.q] effector in C. elegans. | Biological sciences | Erik M. Jorgensen, Susanne Lutz, Stacey L. Williams, Nicole K. Charlie, Christiane Vettel, Michael Ailion, Cassandra Coco, John J.G. Tesmer, Thomas Wieland, Kenneth G. Miller | |||
| TTP and BRF proteins nucleate processing body formation to silence micro-RNAs with AU-rich elements.(tristetraprolin) | Biological sciences | Jens Lykke-Andersen, Tobias M. Franks | |||
| Two small regulatory RNAs establish opposing fates of a developmental axis. | Biological sciences | Michelle T. Juarez, Marja C.P. Timmermans, Fabio T.S. Nogueira, Shahinez Madi, Daniel H. Chitwood | |||
| U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing. | Biological sciences | Angela K. Hilliker, Melissa A. Mefford, Jonathan Staley | |||
| Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation. | Biological sciences | C. David Allis, Hediye Erdjument-Bromage, Paul Tempst, Jason C. Tanny | |||
| Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay. | Biological sciences | Manuel Ares Jr., Julie Z. Ni, Leslie Grate, Christine Preston, Naomi Nobida, Georgeann O'Brien, Lily Shiue, Tyson A. Clark, John E. Blume, John Paul Donohue | |||
| UNC-4 represses CEH-12/HB9 to specify synaptic inputs to VA motor neurons in C. elegans.(Clinical report) | Biological sciences | Jocelyn E. Shaw, Todd A. Starich, Stephen E. Von Stetina, Rebecca M. Fox, Kathie L. Watkins | |||
| Unraveling the crucial roles of Meis1 in leukemogenesis and normal hematopoiesis. | Biological sciences | Eric Yung, R. Keith Humphries, Bob Argiropoulos | |||
| VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization.(Clinical report) | Biological sciences | Olga Pontes, Craig S. Pikaard, Hye Ryun Woo, Eric J. Richards | |||
| Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo.(Chromatin immunoprecipitation coupled with microarray analysis) | Biological sciences | Richard A. Young, Michael Levine, Julia Zeitlinger, Alexander Stark, Manolis Kellis, Robert P. Zinzen, Hailan Zhang | |||
| Yin Yang 1 is a critical regulator of B-cell development. | Biological sciences | Hassan Jumaa, Jane Skok, Yang Shi, Yujiang Shi, Huifei Liu, Roberta Pelanda, Michael Rethd, Marc Schmidt-Supprian, Klaus Rajewsky, Elias Hobeika, Natasha Barteneva | |||
| YY1 helps to bring loose ends together. | Biological sciences | Kathryn Calame, Michael Atchison | |||
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