Nature Medicine 2000 |
Title | Subject | Authors |
$1 million study renews HIV/transplant research.(News) | Health | Potter Wickware |
A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase. | Health | Bernardo Reina-San-Martin, Wim Degrave, Catherine Rougeot, Alain Cosson, Nathalie Chamond, Anabela Cordeiro-da-Silva, Mario Arala-Chaves, Antonio Coutinho, Paola Minoprio |
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer.(Statistical Data Included) | Health | Carla Heise, Fadlo Khuri R., John Nemunaitis, Ian Ganly, James Arseneau, Ian F. Tannock, Larry Romel, Martin Gore, Janet Ironside, R.H. MacDougall, Britta Randlev, Ann M. Gillenwater, Patricia Bruso, Stanley B. Kaye, Waun Ki Hong, David H. Kirn |
A crisis of trust: for science, scientists or for institutions?(Bovine spongiform encephalopathy outbreak in the United Kingdom) | Health | Erik Millstone, Patrick van Zwanenberg |
Active movement of T cells away from a chemokine. | Health | Mark C. Poznansky, Ivona T. Olszak, Russell Foxall, Richard H. EVans, Andrew D. Luster, David T. Scadden |
Activin to the rescue for overexcited neurons. | Health | Mark P. Mattson |
Adhesion of Plasmodium falciparum-infected erythrocytes to hyaluronic acid in placental malaria.(Statistical Data Included) | Health | James G. Beeson, Stephen J. Rogerson, Brian M. Cooke, John C. Reeder, Wengang Chai, Alexander M. Lawson, Malcolm Molyneux, Graham V. Brown |
A DNA chip off the aging block.(News & Views) | Health | Vincent J. Cristofalo |
A dual function for CD40 agonists. | Health | E. Zanelli, R.E.M. Toes |
Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. | Health | M. Steinhoff, N. Vergnolle, S.H. Young, M. Tognetto, S. Amadesi, H.S. Ennes, M. Trevisani, M.D. Hollenberg, J.L. Wallace, G.H. Caughey, S.E. Mitchell, L.M. Williams, P. Geppetti, E.A. Mayer, N.W. Bunnett |
Allogenic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. | Health | Thomas Wekerle, Josef Kurtz, Hiroshi Ito, Joseph V. Ronquillo, Victor Dong, Guiling Zhao, Juanita Shaffer, Mohamed H. Sayegh, Megan Sykes |
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains.(Statistical Data Included) | Health | David Reynolds, Christelle Peyron, Juliette Faraco, William Rogers, Beth Ripley, Sebastiaan Overeem, Yves Charnay, Sona Nevsimalova, Michael Aldrich, Roger Albin, Robin Li, Marcel Hungs, Mario Pedrazzoli, Muralidhara Padigaru, Melanie Kucherlapati, Jun Fan, Richard Maki, Gert Jan Lammers, Constantin Bouras, Kucheralapati Raju, Seiji Nishino, Emmanuel Mignot |
Amyloids: tombstones or triggers? | Health | Robert Kisilevsky |
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy. | Health | Carla Heise, Terry Hermiston, Leisa Johnson, Gabriel Brooks, Adam Sampson-Johannes, Angelica Williams, Lyndah Hawkins, David Kirn |
An endogenous pentapeptide acting as a sodium channel blocker in inflammatory autoimmune disorders of the central nervous system.(Statistical Data Included) | Health | Heinrich Brinkmeier, Peter Aulkemeyer, Kurt H. Wollinsky, Reinhardt Rudel |
A new approach for analyzing proton magnetic resonance spectroscopic images of brain tumors: nosologic images. | Health | Fabian Szabo De Edelenyi, Christophe Rubin, Francois Esteve, Sylvie Grand, Michel Decorps, Virgine Lefournier, Jean-Francois Le Bas, Chantal Remy |
A new biological agent for treatment of Shiga toxigenic Escherichia coli infections and dysentery in humans. | Health | Adrienne W. Paton, Renato Morona, James C. Paton |
A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation.(New Technology) | Health | Dongsheng Duan, Yongping Yue, Ziying Yan, John F. Engelhardt |
A new method for screening anti-infective biomaterials. | Health | Thorsten Bechert, Peter Steinrucke, Josef-Peter Guggenbichler |
Angiopoietin-1 protects the adult vasculature against plasma leakage. | Health | Gavin Thurston, John S. Rudge, Ella Ioffe, Hao Zhou, Leorah Ross, Susan D. Croll, Nicole Glazer, Jocelyn Holash, Donald M. McDonald, George D. Yancopoulos |
An issue of tissues: divining the split personalities of selective estrogen receptor modulators. | Health | Neil J. McKenna, Bert W. O'Malley |
Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. | Health | Isamel Galve-Roperh, Christina Sanchez, Mariu Luisa Cortes, Teresa Gomez del Pulgar, Marta Izquierdo, Manuel Guzman |
A peptide-doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen 'in vivo'. | Health | Deborah DeFeo-Jones, Victor M. Garsky, Bradley K. Wong, Dong-Mei Feng, Trina Bolyar, Kathleen Haskell, David M. Kiefer, Karen Leander, Elizabeth McAvoy, Patricia Lumma, Jenny Wai, Edith T. Senderak, Sherri L. Motzel, Kevin Keenan, Matthew Van Zwieten, Jiunn H. Lin, Roger Freidinger, Joel Huff, Allen Oliff, Raymond E. Jones |
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. | Health | Minji Jo, Tae-Hyoung Kim, Dai-Wu Seol, James E. Esplen, Kenneth Dorko, Timothy R. Billiar, Stephen C. Strom |
A principle target of human immunity to malaria identified by molecular population genetic and immunological analysis. | Health | Brian M. Greenwood, David J. Conway, David R. Cavanagh, Kazuyuki Tanabe, Cally Roper, Zsuzsanna S. Mikes, Naoko Sakihama, Kalifa A. Bojang, Ayoade M.J. Oduola, Peter G. Kremsner, David E. Arnot, Jana S. McBride |
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. | Health | Geoffrey T. Manley, Miki Fujimura, Tonghui Ma, Nobuo Noshita, Ferda Filiz, Andrew W. Bollen, Pak Chan, A.S. Verkman |
A RhoA-derived peptide inhibits syncytium formation induced by respiratory syncytial virus and parainfluenza virus type 3.(Statistical Data Included) | Health | Manoj K. Pastey, Tara L. Gower, Paul W. Spearman, James E. Jr. Crowe, Barney S. Graham |
Artificial antigen-presenting cells as a tool to exploit the immune 'synapse'.(Statistical Data Included) | Health | Berent Prakken, Marca Wauben, Davide Genini, Rodrigo Samodal, Joellen Barnett, Alberto Mendivil, Lorenzo Leoni, Salvatore Albani |
A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor. | Health | Daniel C. Lu, Shahrooz Rabizadeh, Sreeganga Chandra, Rana F. Shayya, Lisa M. Ellerby, Xin Ye, Guy S. Salvesen, Edward H. Koo, Dale E. Bredesen |
Assessing tumors in living animals through measurement of urinary (Beta)-human chorionic gonadotropin. | Health | Kenneth W. Kinzler, Bert Vogelstein, Ie-Ming Shih, Christopher Torrance, Lori J. Sokoll, Daniel W. Chan |
A super way to kill cancer cells. | Health | Barry Halliwell |
Australia to create biomedical lobby group. | Health | Rada Rouse |
Autoimmune encephalomyelitis ameliorated by AMPA antagonists.(alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionate)(Statistical Data Included) | Health | Terence Smith, Anthony Groom, Bin Zhu, Lechoslaw Turski |
Balancing risks on the backs of the poor.(controlling malaria with DDT)(Statistical Data Included) | Health | Amir Attaran, Donald R. Roberts, Chris F. Curtis, Wenceslaus L. Kilama |
Biotechnology industry responds to gene therapy death.(teenager who received adenovirus gene vector died)(News) | Health | Helen Commander |
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo. | Health | R. Atreya, J. Mudter, S. Finotto, J. Mullberg, T. Jostock, S. Wirtz, M. Schutz, B. Bartsch, M. Holtmann, C. BEcker, D. Strand, J. Czaja, J.F. Schlaak, H.A. Lehr, F. Autschbach, G. Schurmann, N. Nishimoto, K. Yoshizaki, H. Ito, T. Kishimoto, P.R. Galle, S. Rose-John, M.F. Neurath |
Blocking bacterial enterotoxins. | Health | |
Bone cancer gain without the pain.(News & Views) | Health | Stephen W.N. Thompson, David Tonge |
Both a 'magic bullet' and good aim are required to link public health interests and health care needs in HIV infection. | Health | R.M. Anderson, G.P. Garnett, L.M. Bartley, D.W. Cameron |
Breaking up receptor alliances: the parting of CD3 and CD4. | Health | Abraham Kupfer |
Can neural stem cells be used as therapeutic vehicles in the treatment of brain tumors?(Commentary) | Health | Mark Noble |
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. | Health | Roger J. Davis, Leo E. Otterbein, Fritz H. Bach, Jawed Alam, Miguel Soares, Hong Tao Lu, Mark Wysk, Richard A. Flavell, Augustine M.K. Choi |
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. | Health | Tal Teitz, Tie Wei, Marcus B. Valentine, Elio F. Vanin, Jose Grenet, Virginia A. Valentine, Frederick G. Behm, A. Thomas Look, Jill M. Lahti, Vincent J. Kidd |
Caspase 8: the killer that you can't live without.(News & Views) | Health | Philippe Juin, Gerard Evan |
Caspase cleavage of APP results in a cytotoxic proteolytic peptide.(News & Views) | Health | Carolanne E. Milligan |
Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C. | Health | Barbara Rehermann, Akinobu Takaki, Manfred Wiese, Geert Maertens, Erik Depla, Ulrike Seifert, Anke Liebetrau, Jeffery L. Miller, Michael P. Manns |
Characterization of a newly discovered T-cell receptor beta-chain heterodimer expressed on a CD8+ bone marrow subpopulation that promotes allogeneic stem cell engraftment. | Health | Matthew J. Schuchert, Renee D. Wright, Yolonda L. Colson |
Chemotherapeutic drugs -- more really is not better.(News & Views) | Health | Isaiah J. Eidler, Lee M. Ellis |
Cholesterol esters and atherosclerosis - a game of ACAT and mouse.(Enzyme acylCoA:cholesterol acyltransferase studied in mice) | Health | Lawrence L. Rudel, Gregory S. Shelness |
Combinatorial chemoprevention of intestinal neoplasia.(Statistical Data Included) | Health | Kenneth W. Kinzler, Bert Vogelstein, Christopher J. Torrance, Peta E. Jackson, Elizabeth Montgomery, Allan Wissner, Maria Nunes, Philip Frost, Carolyn M. Discafani |
Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor. | Health | Shinya Ito, Kyle Northcote Cowan, Adrian Heilbut, Tilman Humpl, Catherine Lam, Marlene Rabinovitch |
Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy. | Health | James G. Fox, Paul Beck, Charles A. Dangler, Mark T. Whary, Timothy C. Wang, Hai Ning Shi, Cathryn Nagler-Anderson |
Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation. | Health | Johnathan B. Rothbard, Sarah Garlington, Qun Lin, Thorsten Kirschberg, Erik Kreider, P. Leo McGrane, Paul A. Wender, Paul A. Khavari |
Containing HIV after infection. | Health | Bruce D. Walker, Eric S. Rosenberg |
Converting hepatocytes to beta-cells -- a new approach for diabetes?(News & Views) | Health | Axel Kahn |
Cyclopentenone prostaglandins -- new allies in the war on inflammation.(News & Views) | Health | Derek A. Willoughby, Adrian R. Moore, Paul R. Colville-Nash |
Cytoadhesion of 'Plasmodium falciparum' ring-stage-infected erythrocytes. | Health | B. Pouvelle, P.A. Buffet, C. Lepolard, A. Scherf, J. Gysin |
Dangerous signals from E. coli toxin.(Escherichia coli) | Health | Albrecht Ludwig, Werner Goebel |
Decoding calcium signals involved in cardiac growth and function. | Health | Eric N. Olson, Timothy A. McKinsey, Norbert Frey |
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. | Health | Richard A. Flavell, Stephane Hunot, Donald W. Nicholson, Timothy S. Zheng, Keisuke Kuida, Takashi Momoi, Anu Srinivasan, Yuri Lazebnik |
De-mystifying the mechanism(s) of maspin.(News & Views) | Health | Mary J.C. Hendrix |
Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4+ T cells. | Health | Toshiaki Kikuchi, Stefan Worgall, Singh Ravi, Malcolm A.S. Moore, Ronald G. Crystal |
Dengue virus and dendritic cells. | Health | Anna Karolina Palucka |
Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya. | Health | Tomas Hanke, Andrew J. McMichael |
Development of an in vitro organ culture model to study transmission of HIV-1 in the female genital tract. | Health | Kelly B. Collins, Bruce K. Patterson, Gregory J. Naus, Daniel V. Landers, Phalguni Gupta |
Directed vascular expression of the thromboxane A(sub)2 receptor results in intrauterine growth retardation. | Health | Bianca Rocca, Alex L. Loeb, Jerome F. Strauss III, Roberta Vezza, Aida Habib, Hongwei Li, Garret A. FitzGerald |
Disruption of positive selection of thymocytes causes autoimmunity. | Health | Anke Kretz-Rommel, Robert L. Rubin |
Distribution of mental health funding questioned. | Health | Marlene Cimons |
Do 'demyelinating' diseases involve more than myelin? | Health | Stephen G. Waxman |
Does Alzheimer disease tilt the scales of amyloid degradation versus accumulation?(News & Views) | Health | Charles Glabe |
Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo.(Statistical Data Included) | Health | Aude G. Chapuis, G. Paolo Rizzardi, Claudia D'Agostino, Antoine Attinger, Christian Knabenhans, Sylvain Fleury, Hans Acha-Orbea, Guiseppe Pantaleo |
Efficient detection and immunomagnetic sorting of specific T cells using multimers of MHC class I peptide with reduced CD8 binding.(major histocompatability complex) | Health | Marie Bodinier, Marie-Alix Peyrat, Claire Tournay, Francois Davodeau, Francois Romagne, Marc Bonneville, Francois Lang |
Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance.(Statistical Data Included) | Health | Andreas Limmer, Jutta Ohl, Christian Kurts, Hans-Gustaf Ljunggren, Yuval Reiss, Marcus Groettrup, Frank Momburg, Bernd Arnold, Percy A. Knolle |
Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. | Health | Rafat Abonour, David A. Williams, Lawrence Einhorn, Kristin M. Hall, Jun Chen, John Coffman, Christie M. Traycoff, Arthur Bank, Ikunoshin Kato, Maureen Ward, Stephen T. Williams, Robert Hromas, Michael J. Robertson, Franklin O. Smith, David Woo, Bonnie Mills, Edward F. Srour, Kenneth Cornetta |
Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress.(zinc-finger transcription factor early growth response)(Statistical Data Included) | Health | Shi-Fang Yan, Tomoyuki Fujita, Jiesheng Lu, Kenji Okada, Yu Shan Zou, Nigel Mackman, David J. Pinsky, David M. Stern |
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-89) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand.(Statistical Data Included) | Health | Bibiana Bielekova, Bonnie Goodwin, Nancy Richert, Irene Cortese, Takayuki Kondo, Ghazaleh Apshar, Bruno Gran, Joan Eaton, Jack Antel, Joseph A. Frank, Henry F. McFarland, Roland Martin |
Epidermal immunization by a needle-free powder delivery technology: immunogenicity of influenza vaccine and protection in mice. | Health | Dexiang Chen, Ryan L. Endres, Cherie A. Erickson, Kathleen F. Weis, Martha W. McGregor, Yoshihiro Kawaoka, Lendon G. Payne |
Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous keukemia.(Statistical Data Included) | Health | Jeffrey J. Molldrem, Peter P. Lee, Changqing Wang, Kyrie Fello, Hagop M. Kantarijan, Richard E. Champlin, Mark M. Davis |
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus.(Statistical Data Included) | Health | David F. Stojdl, Brian Lichty, Shane Knowles, Ricardo Marius, Harold Atkins, Nahum Sonenberg, John C. Bell |
Fas engagement accelerates liver regeneration after partial hepatectomy.(Statistical Data Included) | Health | Julie Desbarats, M. Karen Newell |
Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells.(Statistical Data Included) | Health | Friedemann J. Schaub, David K.M. Han, W. Conrad Liles, Lawrence D. Adams, Scott A. Coats, Ravi K. Ramachandran, Ronald A. Siefert, Stephen M. Schwartz, Daniel F. Bowen-Pope |
Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy. | Health | Peter Schratzberger, Gabrielle Schratzberger, Marcy Silver, Cynthia Curry, Marianne Kearney, Meredith Magner, Joseph Alroy, Lester S. Adelman, David H. Weinberg, Allan H. Ropper, Jeffrey M. Isner |
Fc(alpha)RI-positive liver Kupffer cells: reappraisal of the function of immunoglobulin A in immunity. | Health | Marjolein van Egmond, Evert van Garderen, Annemiek B. van Spriel, Cora A. Damien, Edwin S. van Amersfoort, Ger van Zandbergen, Jan van Hattum, Johan Kuiper, Jan G.J. van de Winkel |
Fetal immunization by a DNA vaccine delivered into the oral cavity.(Statistical Data Included) | Health | Volker Gerdts, Lorne A. Babiuk, Sylvia van Drunen Littel-van-den Hurk, Philip J. Griebel |
Flow cytometry counting of CD34+ cells in whole blood.(Statistical Data Included) | Health | Oscar Fornas, Joan Garcia, Jordi Petriz |
Focal modification of electrical conduction in the heart by viral gene transfer.(Statistical Data Included) | Health | J. Kevin Donahue, Alan W. Heldman, Heather Fraser, Amy D. McDonald, Julie M. Miller, Jeffrey J. Rade, Thomas Eschenhagen, Eduardo Marban |
For want of a disc, the cell was lost....(News & Views) | Health | Alan F. Wright |
From catheters to vectors: the dawn of molecular electrophysiology.(Gene therapy for tachyarrhythmia) | Health | Silvia G. Priori, Carlo Napolitano |
From cell physiology to cell physiology. | Health | Sydney Brenner |
Functional conservation of the malaria vaccine antigen MSP-1[sub]19 across distantly related Plasmodium species.(merozoite surface protein-1[sub]19)(Statistical Data Included) | Health | Alan F. Cowman, Rebecca A. O'Donnell, Allan Saul, Brendan S. Crabb |
Functional deficits in basal ganglia of cihldren with attention-deficit/hyperactivity disorder shown with functional magnetic resonance imaging relaxometry. | Health | Martin H. Teicher, Carl M. Anderson, Ann Polcari, Carol A. Glod, Luis C. Maas, Perry F. Renshaw |
Functional genomics of 'Neisseria meningitidis' pathogenesis. | Health | Yao-Hui Sun, Sharmila Bakshi, Ronald Chalmers, Christoph M. Tang |
Galanin-1 receptor up-regulation mediates the excess colonic fluid production caused by infection with enteric pathogens.(Statistical Data Included) | Health | Matkowskyj. Kristina A., Alexey Danilkovich, Jorge Marrero, Suzana D. Savkovic, Gail Hecht, Richard V. Benya |
Gender differences in HIV-1 diversity at time of infection.(human immunodeficiency virus)(Statistical Data Included) | Health | Julie Overbaugh, E. Michelle Long, Harold L. Jr. Martin, Joan K. Kreiss, Stephanie M.J. Rainwater, Ludo Lavreys, Denis J. Jackson, Joel Rakwar, Kishorchandra Mandaliya |
Generation of primary antigen-specific human T- and B-cell responses in immunocompetent SCID-hu mice.(severe combined immunodeficiency)(Statistical Data Included) | Health | Jose M. Carballido, Reiko Namikawa, Nicole Carballido-Perrig, Svetlana Antonenko, Maria-Grazia Roncarolo, Jan E. de Vries |
Gene therapy: cautious optimism. | Health | Beatrice Renault |
Gene therapy for human SCID: dreams become reality.(severe combined immunodeficiency) | Health | Rebecca H. Buckley |
Gene therapy of experimental brain tumors using neural progenitor cells. | Health | Sara Benedetti, Barbara Pirola, Bianca Pollo, Lorenzo Magrassi, Maria Grazia Bruzzone, Dorotea Rigamonti, Rossella Galli, Silvia Selleri, Francesco Di Meco, Claudio De Fraja, Angelo Vescovi, Elena Cattaneo, Gaetano Finocchiaro |
Gene therapy turns the corner.(human stem cell research) | Health | John E. Dick |
Genetic analysis of chemoresistance in primary murine lymphomas. | Health | Scott W. Lowe, Clemens A. Schmitt, Christine T. Rosenthal |
Genetic correction of sickle cell disease: insights using transgenic mouse models. | Health | Marie-Jose Blouin, Hugues Beauchemin, Adrian Wright, Monique De Paepe, Martin Sorette, Anne-Marie Bleau, Betty Nakamoto, Ching-Nan Ou, Georges Stamatoyannopoulos, Marie Trudel |
Germ cell transplantation: a fertile field. | Health | Howard J. Cooke, Philippa T.K. Saunders |
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor. | Health | Xiao-Yan Zhao, Peter J. Malloy, Aruna V. Krishnan, Srilatha Swami, Nora M. Navone, Donna M. Peehl, David Feldman |
Glutamate excitotoxicity in a model of multiple sclerosis.(Statistical Data Included) | Health | David Pitt, Peter Werner, Cedric S. Raine |
Hate-mail author trapped by DNA.(News) | Health | Laura Bonetta |
Hepatitis C virus and eliminating post-transfusion hepatitis. | Health | Harvey J. Alter, Michael Houghton |
Hepatocyte transplantation in a model of toxin-induced liver disease: variable therapeutic effect during replacement of damaged parenchyma by donor cells. | Health | Kristin M. Braun, Jay L. Degen, Eric P. Sandgren |
High-sensitivity immunoflourescence for detection of the pro- and anti-inflammatory cytokines gamma interferon and interleukin-10 on the surface of cytokine-secreting cells.(Statistical Data Included) | Health | Andreas Radbruch, Alexander Scheffold, Mario Assenmacher, Luzie Reiners-Schramm, Roland Lauster |
High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation. | Health | Iris Goldberg, Iris Barshack, Juri Kopolovic, Iris Lavon, Sharon Amit, Limor Landsman, Steffen Jung, Ben-Zion Tsuberi, Eitan Galun, Hermann Bujard, Yinon Ben-Neriah |
HIV-1 rebound after anti-retroviral therapy.(human immunodeficiency virus- 1) | Health | David D. Ho, Linqi Zhang |
HIV nuclear import: what's the flap? | Health | Mario Stevenson |
HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. | Health | Alexzander Asea, Stine-Kathrein Kraeft, Evelyn A. Kurt-Jones, Mary Ann Stevenson, Lan Bo Chen, Robert W. Finberg, Gloria C. Koo, Stuart K. Calderwood |
Human immunodeficiency virus type 1 reverse transcriptase and protease mutation search engine for queries. | Health | Robert W. Shafer, Duane R. Jung, Bradley J. Betts |
Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after 'in utero' transplantation in sheep. | Health | Alan W. Flake, Kenneth W. Liechty, Tippi C. MacKenzie, Aimen F. Shaaban, Antoneta Radu, AnneMarie B. Moseley, Robert Deans, Daniel R. Marshak |
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. | Health | Timothy W. Baba, Vladimir Liska, Regina Hofmann-Lehmann, Josef Vlasak, Weidong Xu, Seyoum Ayehunie, Lisa A. Cavacini, Marshall R. Posner, Hermann Katinger, Gabriela Stiegler, Bruce J. Bernacky, Tahir A. Rizvi, Russell Schmidt, Lori R. Hill, Michale E. Keeling, Yichen Lu, Joel E. Wright, Ting-Chao Chou, Ruth M. Ruprecht |
Human skin Langerhans cells are targets of dengue virus infection.(Statistical Data Included) | Health | John R. Mascola, Deborah L. Birx, Shuenn-Jue L. Wu, Geraldine Grouard-Vogel, Wellington Sun, Elena Brachtel, Ravithat Putvatana, Mark K. Louder, Luis Filgueira, Mary A. Marovich, Henry K. Wong, Andrew Blauvelt, Gerald S. Murphy, Merlin L. Robb, Bruce L. Innes, Curtis G. Hayes, Sarah Schlesinger Frankel |
Ibuprofen, inflammation and alzheimer disease. | Health | Lennart Mucke, Tony Wyss-Coray |
Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression.(Statistical Data Included) | Health | Zhu-Xu Zhang, Liming Yang, Kevin J. Young, Barb DuTemple, Li Zhang |
Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury. | Health | Elizabeth G. Nabel, Nancy J. Sullivan, Zhi-yong Yang, Henricus J. Duckers, Anthony Sanchez, Nabel Gary J. |
Identification of the major Abeta(sub)(1-42)-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition. | Health | Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, Karori Watanabe, Misaki Sekiguchi, Emi Hosoki, Maho Kawashima-Morishima, Hahn-Jun Lee, Emi Hama, Yoko Sekine-Aizawa, Takaomi C. Saido |
IgG surfaces as an important component in mucosal protection.(News & Views) | Health | Marjorie Robert-Guroff |
Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies. | Health | Andreas Trojan, Joachim L. Schultze, Mathias Witzens, Robert H. Vonderheide, Marco Ladetto, John W. Donovan, Gribben John G. |
Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue. | Health | Fadi G. Lakkis, Alexandr Arakelov, Bogumila T. Konieczny, Yoshihiko Inoue |
Immunomodulation: a new role for statins? | Health | Wulf Palinski |
Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine. | Health | Yu-Quan Wei, Qing-Ru Wang, Xia Zhao, Li Yang, Ling Tian, You Lu, Bin Kang, Chong-Jiu Lu, Mei-Juan Huang, Yan-Yan Lou, Fei Xiao, Qiu-Ming He, Jing-Mei Shu, Xing-Jiang Xie, Yun-Qiu Mao, Shong Lei, Feng Luo, Li-Qun Zhou, Chong-En Liu, Hao Zhou, Yu Jiang, Feng Peng, Liang-Ping Yuan, Qiu li, Yang Wu, Ji-Yan Liu |
Import of host delta-aminolevulinate dehydratase into the malaraial parasite: identification of a new drug target. | Health | Z.Q. Bonday, S. Dhanasekaran, P.N. Rangarajan, G. Padmanaban |
Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1. | Health | Erwin F. Wagner, Wolfram Jochum, Jean-Pierre David, Candace Elliot, Anton Wutz, Hanns Jr. Plenk, Koichi Matsuo |
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection.(Statistical Data Included) | Health | Tobias F. Rinke de Wit, Mette D. Hazenberg, Sigrid A. Otto, James W.T. Cohen Stuart, Martie C.M. Verschuren, Jan C.C. Borleffs, Charles A.B. Boucher, Roel A. Coutinho, Joep M.A. Lange, Aster Tsegaye, Jacques J.M. van Dongen, Dorte Hamann, Rob J. de Boer, Frank Miedema |
Increased sensitivity to the stimulant effects of morphine conferred by anti-adhesive glycoprotein SPARC in amygdala. | Health | Toru Imamura, Mitsushi Ikemoto, Masatoshi Takita, Koutarou Inoue |
Induction of activin A is essential for the neuroprotective action of basic fibroblast growth factor in vivo.(Statistical Data Included) | Health | Yvonne P. Tretter, Moritz Hertel, Barbara Munz, Gerrit ten Bruggencate, Sabine Werner, Christian Alzheimer |
Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial.(Statistical Data Included) | Health | Lawrence Steinman, Jack Antel, Ludwig Kappos, Giancarlo Comi, Hillel Panitch, Joel Oger, Paul Conlon |
Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells. | Health | Smita K Nair, Axel Helser, David Boczkowski, Anish Majumdar, Michio Naoe, Jane S. Lebkowski, Johannes Vieweg, Eli Gilboa |
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. | Health | Raphael A. Clynes, Terri L. Towers, Leonard G. Presta, Jeffrey V. Ravetch |
In situ detection of virus- and tumor-specific T-cell immunity.(Statistical Data Included) | Health | John B.A.G. Haanen, Monique G.C.T. van Oijen, Felicia Tirion, Lauran C.J.M. Oomen, Ada M. Kruisbeek, Florry A. Vyth-Dreese, Ton N.M. Schumacher |
Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis.(Statistical Data Included) | Health | A.B. Al-Mehdi, K. Tozawa, A.B. Fisher, L. Shientag, A. Lee, R.J. Muschel |
In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. | Health | Neeta Singh Roy, Su Wang, Li Liang, Jian Kang, Abdellatif Benraiss, Catherine Harrison-Restelli, Richard A.R. Fraser, William T. Couldwell, Ayano Kawaguchi, Hideyuki Okano, Maiken Nedergaard, Steven A. Goldman |
In vivo antigen challenge in celiac disease indentifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope. | Health | Robert P. Anderson, Pilar Degano, Andrew J. Godkin, Derek P. Jewell, Adrian V.S. Hill |
In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation.(Statistical Data Included) | Health | William C. Sessa, Mariarosaria Bucci, Jean-Philippe Gratton, Radu Daniel Rudic, Lisette Acevedo, Fiorentina Roviezzo, Giuseppe Cirino |
In vivo magnetic resonance imaging of transgene expression. | Health | Ralph Weissleder, Anna Moore, Umar Mahmood, Rajeev Bhorade, Helene Benveniste, E. Antonio Chiocca, James P. Basilion |
In vivo veritas: the search for TB drug targets goes live.(tuberculosis) | Health | John D. McKinney |
Is the development of a new tuberculosis vaccine possible? | Health | Stefan H.E. Kaufmann |
Is the UK ready for an NCI?(National Cancer Institute)(Editorial) | Health | |
Italy creates neuroscience network.(News) | Health | Martina Ballmaier |
Keeping in touch with angiogenesis.(News & Views) | Health | Lloyd Paul Aiello |
Kissing cousins - evidence for a common vascular cell precursor. | Health | Patricia A. D'Amore |
Kourilsky to reform the Pasteur Institute.(Philippe Kourilsky) | Health | Heather McCabe |
Latent Mycobacterium tuberculosis - persistence, patience, and winning by waiting. | Health | William R. Bishai, Yukari C. Manabe |
Leaky vessels? Call Ang1!(News & Views) | Health | Rakesh K. Jain, Lance L. Munn |
Learning old tricks from new viruses. | Health | Karl Munger |
Limitin: an interferon-like cytokine that preferentially influences B-lymphocyte precursors. | Health | Yuji Matsuzawa, Kenji Oritani, Kay L. Medina, Yoshiaki Tomiyama, Jun Ishikawa, Yu Okajima, Megumu Ogawa, Yokota Takahumi, Keisuke Aoyama, Isao Takahashi, Paul W. Kincade |
Linking Helicobacter pylori to gastric cancer.(News & Views) | Health | Martin J. Blaser |
Listening for hoof beats in heart beats. | Health | Jeffrey Robbins, Gerald W. Dorn |
LMP2 expression and proteasome activity in NOD mice.(Letter to the Editor) | Health | Benedikt M. Kessler, Ana-Maria Lennon-Dumenil, Mari L. Shinohara, Myra A. Lipes, Hidde L. Ploegh, Herbert A. Runnels, Wendy A. Watkins, John J. Monaco, Takuma Hayashi, Shohta Kodama, Denise L. Faustman |
Loss of p14(sup)ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015). | Health | Stefan J. Ries, Christian H. Brandts, Alicia S. Chung, Carola H. Biederer, Byron C. Hann, Ettie M. Lipner, Frank McCormick, W. Michael Korn |
Malaria transmission-blocking vaccines - how can their development be supported? | Health | Allan Saul, Richard Carter, Kamini N. Mendis, Louis H. Miller, Louis Molineaux |
Malaria vaccines-targeting infected hepatocytes. | Health | Stephen L. Hoffman, Denise L. Doolan |
Mammalian deconstruction for stem cell reconstruction. | Health | Ron McKay |
Maspin is an angiogenesis inhibitor. | Health | Ming Zhang, Olga Volpert, Yihui H. Shi, Noel Bouck |
Measles vaccines: a positive step toward eradicating a negative strand. | Health | Ann M. Arvin |
Meningococcal genomics: two steps forward, one step back. | Health | Ian M. Feavers, Martin C. Maiden |
Metformin reverses fatty liver disease in obese, leptin-deficient mice.(Statistical Data Included) | Health | Hui Zhi Lin, Shi Qi Yang, Christine Chuckaree, Francis Kuhajda, Gabriele Ronnet, Anna Mae Diehl |
Mice without telomerase: what can they teach us about human cancer? | Health | Ronald A. DePinho, Steven E. Artandi |
MIF mediation of sepsis.(macrophage migration inhibitory factor)(News & Views) | Health | Thomas R. Martin |
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease.(Statistical Data Included) | Health | Jean-Paul Vonsattel, Minghua Chen, Victor O. Ona, Mingwei Li, Robert J. Ferrante, Klaus B. Fink, Shan Zhu, Jie Bian, Lei Guo, Laurie Farrell, Steve M. Hersch, Wendy Hobbs, Jang-Ho J. Cha, Robert M. Friedlander |
Mitochondrial control of cell death.(Review) | Health | Guido Kroemer, John C. Reed |
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway. | Health | Shigekazu Nagata, Koji Tamada, Koji Shimozaki, Andrei I. Chapoval, Gefeng Zhu, Gabriel Sica, Dallas Flies, Tom Boone, Hailing Hsu, Yang-Xin Fu, Jian Ni, Lieping Chen |
Molecular mimicry mediated by MHC class Ib molecules after infection with Gram-negative pathogens. | Health | Wei-Feng Lo, Amina S. Woods, Amy DeCloux, Robert J. Cotter, Eleanor S. Metcalf, Mark J. Soloski |
Monclonal antibody therapies -- a 'constant' threat to cancer.(News & Views) | Health | Alan N. Houghton, David A. Scheinberg |
Multiple approaches to multiple sclerosis. | Health | Lawrence Steinman |
Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease. | Health | Chun Kung, Jeanette T. Pingel, Markku Heikinheimo, Timo Klemola, Kari Varkila, Lina I. Yoo, Katri Vuopala, Minna Poyhonen, Matti Uhari, Martin Rogers, Samuel H. Speck, Talal Chatila, Matthew L. Thomas |
Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro. | Health | Hiroki Aoki, Junichi Sadoshima, Seigo Izumo |
Neuronal progenitors - learning from the hippocampus.(Review) | Health | Jack P. Antel, Josephine Nalbantoglu, Andre Olivier |
Neuroprotective autoimmunity -- a double-edged sword?(News & Views) | Health | Matthew J.A. Wood, Angela Vincent |
New feelings about the role of sensory nerves in inflammation.(News & Views) | Health | Susan D. Brain |
New islets from old.(pancreatic cells) | Health | David H. Sachs, Susan Bonner-Weir |
New multi-determinant strategy for a group A streptococcal vaccine designed for the Australian Aboriginal population. | Health | Evelyn R. Brandt, K.S. Sriprakash, Rhonda I. Hobb, Wendy A. Hayman, Weiguang Zeng, Michael R. Batzloff, David C. Jackson, Michael F. Good |
'New variant' Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. | Health | Moira E. Bruce |
NIH gives money for orphan development.(National Institutes of Health) | Health | Myrna E. Watanabe |
NIH revamps HIV vaccine trials unit.(News) | Health | Potter Wickware |
Normal and mutant huntingtin: partners in crime? | Health | Nicholas A. Di Prospero, Danilo A. Tagle |
Not a minute to waste.(understanding muscle development and decay) | Health | George E.O. Muscat, Uwe Dressel |
Not so fas: re-evaluating the mechanisms of immune privilege and tumor escape.(Commentary) | Health | Nicholas P. Restifo |
Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy.(Statistical Data Included) | Health | Gloria I. Perez, Jonathan L. Tilly, John C. Reed, Yutaka Morita, Francois Paris, Silvia R. Miranda, Desiree Ehleiter, Adrianna Haimovitz-Friedman, Zvi Fuks, Zhihua Xie, Edward H. Schuchman, Richard N. Kolesnick |
'Orphans' meet cholesterol. | Health | Alan R. Tall, Phillipe Costet, Yi Luo |
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord. | Health | Prisca Honore, Nancy M. Luger, Mary Ann C. Sabino, Matthew J. Schwei, Scott D. Rogers, David B. Mach, Patrick F. O'Keefe, Margaret L. Ramnaraine, Denis R. Clohisy, Patrick W. Mantyh |
Overcoming adeno-associated virur vector size limitation through viral DNA heterodimerization.(New Technology) | Health | Liangwu Sun, Xiao Xiao, Juan Li |
Overexpression of deltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis. | Health | J. Chen, G. Sabatakos, N.A. Sims, K. Aoki, M.B. Kelz2, M. Amling, Y. Bouali, K. Mukhopadhyay, K. Ford, E.J. Nestler, R. Baron |
Overexpression of the alpha(1B)-adrenergic receptor causes apoptotic neurodegeneration: multiple system atrophy.(Statistical Data Included) | Health | Michael J. Zuscik, Scott Sands, Sean A. Ross, David J.J. Waugh, Robert J. Gaivin, David Morilak, Dianne M. Perez |
Oxidation versus aggregation - how do SOD1 mutants cause ALS?(superoxide dismutase 1)(amyotrophic lateral sclerosis) | Health | Don W. Cleveland, Jian Liu |
p27(super)kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes. | Health | Vassiliki A. Boussiotis, Gordon J. Freeman, Patricia A. Taylor, Alla Berezovskaya, Isaabelle Grass, Bruce R. Blazar, Lee M. Nadler |
Pain, plasticity, and premature birth: a prescription for permanent suffering? | Health | K.J.S. Anand |
Pancreatic and duodenal homeobox gene 1 induces experssion of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. | Health | Sarah Ferber, Amir Halkin, Hofit Cohen, Idit Ber, Yulia Einav, Iris Goldberg, Iris Barshack, Rhona Seijffers, Juri Kopolovic, Nurit Kaiser, Avraham Karasik |
Pancreatic expression of infection-y protects mice from lethal coxsackievirus B3 interferon(gamma) and subsequent myocarditis. | Health | Marc S. Horwitz, Antonio La Cava, Cody Fine, Enrique Rodriguez, Alex Ilic, Nora Sarvetnick |
Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population. | Health | David E. Anderson, Katarzyna D. Bieganowska, Amit Bar-Or, Enedina M.L. Oliveira, Beatriz Carreno, Mary Collins, David A. Hafler |
Parkinson disease gene therapy moves toward the clinic. | Health | Anders Bjorklund, Olle Lindvall |
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease.(Statistical Data Included) | Health | Frederique Bard, Catherine Cannon, Robin Barbour, Rae-Lyn Burke, Dora Games, Henry Grajeda, Teresa Guido, Kang Hu, Jiping Huang, Kelly Jhonson-Wood, Karen Khan, Dora Kholodenko, Mike Lee, Ivan Lieberburg, Ruth Motter, Minh Nguyen, Ferdie Soriano, Nicki Vasquez, Kim weiss, Brent Welch, Peter seubert, Dale Schenk, Ted Yednock |
Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy.(Statistical Data Included) | Health | Graeme Moyle, Mark E. Sharkey, Ian Teo, Thomas Greenough, Natalia Sharova, Katherine Luzuriaga, John Lawrence Sullivan, R. Pat Bucy, Leondios G. Kostrikis, Ashley Haase, Claire Veryard, Raul E. Davaro, Sarah H. Cheeseman, Jennifer S. Daly, Carol Bova, Richard T. III Ellison, Brian Mady, Kwan Kew Lai, Mark Nelson, Brian Gazzard, Sunil Shaunak, Mario Stevenson |
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch 1 signaling. | Health | Barbara Varnum-Finney, Lanwei Xu, Carolyn Brashem-Stein, Cynthia Nourigat, David Flowers, Sonia Bakkour, Warren S. Pear, Irwin D. Bernstein |
Pointing (zinc) fingers at BRCA1 targets.(breast cancer genes) | Health | Timothy K. MacLachlan, Wafik S. El-Deiry |
Positive selection for autoimmunity. | Health | Syamal K. Datta |
Pot of gold for glioma therapy.(medical marijuana) | Health | Daniele Piomelli |
PR39, a peptide regulator of angiogenesis.(Statistical Data Included) | Health | Jian Li, Mark Post, Rudiger Volk, Youthe Gao, Min Li, Caroline Metais, Kaori Sato, Jo Tsai, William Aird, Robert D. Rosenberg, Thomas G. Hampton, Jianyi Li, Frank Sellke, Peter Carmeliet, Michael Simons |
Prostate cancer schemes for androgen escape. | Health | ALbert O. Brinkmann, Jan Trapman |
Protecting the female germ line from cancer therapy. | Health | Robert F. Casper, Andrea Jurisicova |
Protection against 'Plasmodium falciparum' malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3. | Health | Guy Dubreuil, Pierre Daubersies, Alan W. Thomas, Pascal Millet, Karima Brahimi, Jan A.M. Langermans, Benjamin Ollomo, Lbachir Ben Mohamed, Bas Slierendregt, Wijnand Eling, Alex Van Belkum, Jacques F.G.M. Meis, Claudine Guerin-Marchand, Sylvie Cayphas, Joe Cohen, Helene Gras-Masse, Pierre Druilhe |
Protection from septic shock by neutralization of macrophage migration inhibitory factor. | Health | Thierry Calandra, Bernd Echtenacher, Didier Le Roy, Jerome Pugin, Christine N. Metz, Lothar Hultner, Didier Heumann, Daniela Mannel, Richard Bucala, Michel P. Glauser |
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. | Health | Hermann Katinger, Gabriela Stiegler, John R. Mascola, Thomas C. VanCott, Calvin B. Carpenter, Chris E. Hanson, Holly Beary, Deborah Hayes, Sarah S. Frankel, Deborah L. Birx, Mark G. Lewis |
Public-private partnerships for public health. | Health | Michael R. Reich |
Purified hematopoietic stem cells can differentiate into hepatocytes 'in vivo'. | Health | Irving Weissman, Eric Lagasse, Heather Connors, Muhsen Al-Dhalimy, Michael Reitsma, Monika Dohse, Linda Osborne, Xin Wang, Milton Finegold, Markus Grompe |
Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis.(Statistical Data Included) | Health | Oren Zimhony, Jeffery S. Cox, John T. Welch, Catherine Vilcheze, William R. Jr. Jacobs |
Quantification of target gene expression by imaging reporter gene expression in living animals. | Health | Alexander J. Annala, Michael E. Phelps, Simon R. Cherry, Yajing Yu, Jorge R. Barrio, Tatsushi Toyokuni, Nagichettiar Satyamurthy, Mohammad Namavari, Harvey R. Herschman, Sanjiv S. Gambhir |
Receptor-dependent cell stress and amyloid accumulation in systematic amyloidosis. | Health | Shi Du Yan, Huaijie Zhu, Aiping Zhu, Adam Golabek, Hong Du, Alex Roher, Jin Yu, Claudio Soto, Ann Marie Schmidt, David Stern, Mark Kindy |
Recombinant lipid-tagged antibody fragments as functional cell-surface receptors.(New Technology) | Health | John de Kruif, Marella Tijmensen, Joel Goldsein, Ton Logtenberg |
Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas.(Statistical Data Included) | Health | Hiroaki Higashitsuji, Katsuhiko Itoh, Toshikazu Nagao, Simon Dawson, Kohsuke Nonoguchi, R.John Mayer, Tsuneo Kido, Shigeki Arii, Jun Fujita |
Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids. | Health | Gerhard A. Muller, Alexander Kugler, Gernot Stuhler, Peter Walden, Gerhard Zoller, Anke Zobywalksi, Peter Brossart, Uwe Trefzer, Silke Ullrich, Claudia A. Muller, Volker Becker, Andreas J. Gross, Hemmerlein Bernhard, Lothar Kanz, Rolf-Hermann Ringert |
Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy. | Health | Tae-Wook Chun, Richard T. Jr. Davey, Mario Ostrowski, J. Shawn Justement, Delphine Engel, James I. Mullins, Anthony S. Fauci |
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice.(acyl CoA:cholesterol acyltransferase)(Statistical Data Included) | Health | Kimberly K. Buhman, Michel Accad, Sabine Novak, Rebekah S. Choi, Jinny S. Wong, Robert L. Hamilton, Stephen Turley, Robert V. Farese Jr. |
Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. | Health | Vijayakumar K. Ramiya, Michael Maraist, Karl E. Arfors, Desmond A. Schatz, Ammon B. Peck, Janet G. Cornelius |
Sacked Spanish oncologists win reprieve.(researchers at the Oncology Research Institute)(News) | Health | Xavier Bosch |
Sane genetics for schizophrenia. | Health | Brien Riley, Robert Williamson |
Science and politics - a broken union.(Public inadequately informed of research findings)(Editorial) | Health | |
Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing. | Health | Gillian S. Ashcroft, Kejian Lei, Wenwen Jin, Glenn Longenecker, Ashok B. Kulkarni, Teresa Greenwell-Wild, Hollie Hale-Donze, George McGrady, Xiao-Yu Song, Sharon M. Wahi |
Seeing what Alzheimer saw--with magnetic resonance microscopy.(Alois Alzheimer) | Health | N.C. Fox, M.N. Rossor |
Sex and the genetic diversity of HIV-1.(human immunodeficiency virus) | Health | Thomas C. Quinn, Stuart C. Ray |
Seymour S. Kety, 1915-2000.(medical scientist)(Obituary) | Health | Philip S. Holzman |
Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.(Statistical Data Included) | Health | Ludger Klein, Matthias Klugmann, Klaus-Armin Nave, Vincent K. Tuohy, Bruno Kyewski |
Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1.(Statistical Data Included) | Health | Noel Bouck, Benilde Jimenez, Olga V. Volpert, Susan E. Crawford, Maria Febbraio, Roy L. Silverstein |
Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice.(Statistical Data Included) | Health | Bing Li, Lorraine A. Nolte, Jeong-Sun Ju, Dong Ho Han, Trey Coleman, John O. Holloszy, Clay F. Semenkovich |
Skin stem cells - a hairy issue. | Health | Colin Jahoda, Amanda Reynolds |
Smallpox, polio and now a cancer vaccine? | Health | Donald W. Kufe |
Sniffing out new approaches to spinal cord repair.(News & Views) | Health | Geoffrey Raisman |
South African village prepares for first HIV vaccine trial... | Health | Harold Connett |
Specific immunotherapy: one size does not fit all. | Health | Claude P. Genain, Scott S. Zamvil |
Split stories converge at desmoglein 1. | Health | Ervin Epstein Jr. |
Statins as a newly recognized type of immunomodulator.(Statistical Data Included) | Health | Brenda Kwak, Flore Mulhaupt, Samir Myit, Francois Mach |
Statins: lower lipids and better bones? | Health | M.J. Rogers |
Steering anti-cancer drugs away from the TRAIL.(tumor necrosis factor-related apoptosis-inducing ligand)(News & Views) | Health | Shigekazu Nagata |
Stem cell alchemy. | Health | Stuart H. Orkin |
Stem cell repopulation efficiency but not pool size is governed by p27(kip1). | Health | David T. Scadden, Tao Cheng, Neil Rodrigues, David Dombkowski, Sebastian Stier |
Stem cells - why wait?(Editorial) | Health | Beatrice Renault |
Sticky sugars attract malaria to the fetus. | Health | |
Successful DNA immunization against measles: neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles.(Statistical Data Included) | Health | Fernando P. Polack, Sok H. Lee, Sallie Permar, Elizabeth Manyara, Hossein G. Nousari, Yaikah Jeng, Farah Mustafa, Alexandra Valsamakis, Robert J. Adams, Harriet L. Robinson, Diane E. Griffin |
Superantigen antagonist protects against lethal shock and defines a new domain for T-cell activation. | Health | Gila Arad, Revital Levy, Dalia Hillman, Raymond Kaempfer |
Suppression of tumor growth through disruption of hypoxia-inducible transcription.(Statistical Data Included) | Health | Andrew L. Kung, David M. Livingston, William G. Kaelin Jr., Stream Wang, Jeffery M. Klco |
Supression of tumor growth and metastasis in Mgat5-deficient mice. | Health | Maria Granovsky, Jimmie Fata, Judy Pawling, William J. Muller, Rama Khokha, James W. Dennis |
Sustained survival of human hepatocytes in mice: a model for in vivo infection with human hepatitis B and hepatitis delta viruses. | Health | Hiroyuki Nakai, Mark A. Kay, Kazuo Ohashi, Patricia L. Marion, Leonard Meuse, John M. Cullen, Bruno B. Bordier, Ralph Schwall, Harry B. Greenberg, Jeffrey S. Glenn |
Systemic sclerosis immunoglobulin G autoantibodies bind the human cytomegalovirus late protein UL94 and induce apoptosis in human endothelial cells. | Health | Roberto Corrocher, Claudio Lunardi, Caterina Bason, Riccardo Navone, Enrico Millo, Gianluca Damonte, Antonio Puccetti |
TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. | Health | Dou Zhang, Vinciane Gaussin, George E. Taffet, Narasimhaswamy S. Belaguli, Miho Yamada, Robert J. Schwartz, Lloyd H. Michael, Paul A. Overbeek, Michael D. Schneider |
Taking aim at HIV replication.(human immunodeficiency virus) | Health | Robert F. Siliciano, Diana Finzi |
Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.(Statistical Data Included) | Health | Bradford B. Lowell, Ariel Zisman, Odile D. Peroni, E. Dale Abel, M. Dodson Michael, Franck Mauvais-Jarvis, Jorgen F.P. Wojtaszewski, Michael F. Hirshman, Antti Virkamaki, Laurie J. Goodyear, C. Ronald Kahn, Barbara B. Kahn |
Targeting tumors through the HIF system.(hypoxia-inducible factor) | Health | Peter J. Ratcliffe, Christopher W. Pugh, Patrick H. Maxwell |
Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse teleomere biology. | Health | Jerry W. Shay, Woodring E. Wright |
The 3' untranslated region of messenger RNA: a molecular 'hotspot' for pathology? | Health | Beatrice Conne, Andre Stutz, Jean-Dominique Vassalli |
The axis of interleukin 12 and gamma interferon regulates acute vascular xenogeneic rejection. | Health | Wang Hao, Mark E. DeVries, Shaoping Deng, Masud H. Khandaker, J. Geoff Pickering, Larry H. Chow, Bertha Garcia, David J. Kelvin, Robert Zhong |
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen.(Statistical Data Included) | Health | Shane Crotty, David Maag, Jamie J. Arnold, Weidong Zhong, Johnson Y.N. Lau, Zhi Hong, Raul Andino, Craig E. Cameron |
The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development. | Health | Dimitrios Balomenos, Juan Martin-Caballero, Maria I. Garcia, Ignacio Prieto, Juana M. Flores, Manuel Serrano, Carlos Martinez-A |
The changing face of biomedical research?(Editorial) | Health | |
The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy.(Statistical Data Included) | Health | |
The Declaration of Helsinki, CIOMS and the ethics of research on vulnerable populations.(Council for International Organizations of Medical Science) | Health | Deborah Zion, Lynn Gillam, Bebe Loff |
The envelope, please: nuclear lamins and disease.(News & Views) | Health | Robert A. Hegele |
The Ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis. | Health | Xiangming Xing, Shao-Chun Wang, Weiya Xia, Yiyu Zou, Ruping Shao, Ka Yin Kwong, Zhenming Yu, Su Zhang, Susan Miller, Leaf Huang, Mien-Chie Hung |
The fine cytokine line between graft acceptance and rejection.(News & Views) | Health | Zoie E. Holzknecht, Jeffrey L. Platt |
The first steps on the gene therapy pathway to anti-sickling success.(News & Views) | Health | Stefan Karlsson |
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.(Statistical Data Included) | Health | Yasuko Kureishi, Zhengyu Luo, Ichiro Shiojima, Ann Bialik, David Fulton, David J. Lefer, William C. Sessa, Kenneth Walsh |
The latent nuclear antigen of kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells. | Health | Stoyan A. Radkov, Paul Kellam, Chris Boshoff |
The mammary gland iodide transporter is expressed during lactation and in breast cancer. | Health | Uygar H. Tazebay, Irene L. Wapnir, Orlie Levy, Orsolya Dohan, Lionel S. Zuckier, Qing Hua Zhao, Hou Fu Deng, Peter S. Amenta, Susan Finberg, Richard G. Pestell, Nancy Carrasco |
The National Intitutes of Health and clinical research: a progress report. | Health | David G. Nathan, Harold E. Varmus |
The need for private-public partnerships.(to promote biomedical research)(Editorial) | Health | |
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells.(Statistical Data Included) | Health | Patrick Lawinger, Radjendirane Venugopal, Zong-Sheng Guo, Anand Immaneni, Devjani Sengupta, Wenying Lu, Luca Rastelli, Ana Marin Dias Carneiro, Victor Levin, Gregory N. Fuller, Yann Echelard, Sadhan Majumder |
The nuclear receptor co-repressor Nrip1 (RIP140) is essential for female fertility.(Statistical Data Included) | Health | Roger White, Goran Leonardsson, Ian Rosewell, Mary Ann Jacobs, Stuart Milligan, Malcolm Parker |
The proglucagon-derived peptide, glucagon-like peptide-2, is a neurotransmitter involved in the regulation of food intake.(Statistical Data Included) | Health | Mads Tang-Christensen, Philip Just Larsen, Jesper Thulesen, John Romer, Niels Vrang |
Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic inflammatory process. | Health | Claudia Mauri, Lennart T. Mars, Marco Londei |
The sleep-wake switch: a neuronal alarm clock.(News & Views) | Health | Dennis McGinty, Ron Szymusiak |
The trophoblast is a component of the innate immune system during pregnancy. | Health | Jeffrey W. Pollard, Indira Guleria |
The tyrosine kinase p56(super lck) is essential in coxsackievirus B3-mediated heart disease. | Health | Kurt Bachmaier, Ivona Kozieradzki, Young-Yun Kong, Josef Penninger, Tak W. Mak, Peter Liu, Karen Aitken, Mary Anne Opavsky, Tammy Martino, Fayez Dawood, Wen-Hu Wen, David Straus |
The ubiquitin system. | Health | Alexander Varshavsky, Avram Hershko, Aaron Ciechanover |
The vision of Typhoon Lengkieki.(population genetics in Micronesia) | Health | Val C. Sheffield |
To be or notch to be.(Notch signaling) | Health | Malcolm Brenner |
Toxin in bollous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. | Health | M. Amagai, N. Matsuyoshi, Z.H. Wang, C. Andl, J.R. Stanley |
Transcriptional regulation of cellular transformation. | Health | Paolo Salomoni, Pier Paolo Pandolfi |
Transcutaneous immunization: a human vaccine delivery strategy using a patch.(Statistical Data Included) | Health | Gregory M. Glenn, David N. Taylor, Xiuru Li, Sarah Frankel, Andrew Montemarano, Carl R. Alving |
Transdermal monitoring of glucose and other analytes using ultrasound. | Health | Joseph Kost, Samir Mitragotri, Robert A. Gabbay, Michael Pishko, Robert Langer |
Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection.(Statistical Data Included) | Health | Peter J. Nelson, Matthias Mack, Andrea Kleinschmidt, Hilke Bruhl, Christiane Klier, Josef Cihak, Jiri Plachy, Manfred Stangassinger, Volker Erfle, Detlef Schlondorff |
Transmissible spongiform encephalopathies, amyloidoses and yeast prions: common threads? | Health | Byron Caughey |
Transplantation of male germ line stem cells restores fertility in infertile mice.(Statistical Data Included) | Health | Takehiko Ogawa, Ina Dobrinski, Mary R. Avarbock, Ralph L. Brinster |
UK speculated to permit stem cell research.(News) | Health | Phyllida Brown |
Uncoupling diet and diabetes. | Health | Leslie P. Kozak |
Uptake of HIV-1 Tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands.(transactivator protein)(Statistical Data Included) | Health | Ying Liu, Melina Jones, Cynthia M. Hingtgen, Guojun Bu, Nick Laribee, Rudolph E. Tanzi, Robert D. Moir, Avindra Nath, Johnny J. He |
Vaccines and the induction of functional antibodies: time to look beyond the molecules of natural infection?(Commentary) | Health | Dennis R. Burton, Paul W.H.I. Parren |
Varicella vaccination: evidence for frequent reactivation of the vaccine strain in healthy children. | Health | Philip R. Krause, Dennis M. Klinman |
Varicella-zoster vaccine: the bad news may be good.(News & Views) | Health | John Mills |
Viral damage or 'molecular mimicry': placing the blame in myocarditis. | Health | Noel R. Rose |
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