| Cell 1995 |
| Title | Subject | Authors |
|---|
| 15-deoxy-Delta(super 12,14)-prostaglandin J(sub 2) is a ligand for the adipocyte determination factor PPAR(sub gamma).(peroxisome proliferator-activated receptor gamma isoform) | Biological sciences | Ronald M. Evans, Bruce M. Spiegelman, Peter Tontonoz, Barry M. Forman, Jasmine Chen, Regina P. Brun |
| A 20S complex containing CDC27 and CDC16 catalyses the mitosis-specific conjugation of ubiquitin to cyclin B. | Biological sciences | Marc W. Kirschner, Jan-Michael Peters, Stuart Tugendreich, Philip Hieter, Randall W. King, Mark Rolfe |
| Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes. | Biological sciences | Alan W. Harris, Jerry M. Adams, Thomas Metz |
| A central role for microvillous receptor presentation in leukocyte adhesion under flow. | Biological sciences | Eugene C. Butcher, Ulrich H. Von Andrian, Sharon R. Hasslen, Robert D. Nelson, Stanley L. Erlandsen |
| Acetlycholinesterase inhibition by fasciculin: crystal structure of the complex. | Biological sciences | Palmer Taylor, Yves Bourne, Pascale Marchot |
| A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. | Biological sciences | Leland H. Hartwell, Amanda G. Paulovich |
| Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease). | Biological sciences | Bernd Otterbach, Wilhelm Stoffel |
| A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy. | Biological sciences | Brunella Franco, Andrea Ballabio, Giancarlo Parenti, Germana Meroni, Christine Petit, Marinella Gebbia, Jacqueline Levilliers, Loris Bernard, Liza Cox, Pierre Maroteaux, Leslie Sheffield, Gudrun A. Rappold, Generoso Andria |
| Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus. | Biological sciences | Carol Prives, Lata Jayaraman |
| A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei. | Biological sciences | David Horn, George A.M. Cross |
| A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. | Biological sciences | Susan Winandy, Paul Wu, Katia Georgopoulos |
| A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation. | Biological sciences | Tatiana I. Gerasimova, Victor G. Corces, David A. Gdula, Denis V. Gerasimov, Olga Simonova |
| A fibrillar collagen gene, Col 11a1, is essential for skeletal morphogenesis. | Biological sciences | Y. Li, Y. Ninomiya, D.A. Lacerda, M.L. Warman, D.R. Beier, H. Yoshioka, J.T. Oxford, N.P. Morris, K. Andrikopoulos, F. Ramirez |
| A floral transmitting tissue-specific glycoprotein attracts pollen tubes and stimulates their growth. | Biological sciences | Hong Wang, Alice Y. Cheung, Hen-ming Wu |
| A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning.(protein kinase A, long-term potentiation) | Biological sciences | Eric R. Kandel, Yan-You Huang, Lauren Varshavsky, Eugene P. Brandon, Ming Qi, Rejean L. Idzerda, G. Stanley McKnight, Roussoudan Bourtchouladze |
| A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility. | Biological sciences | Alan M. Lambowitz, Jian Yang, Philip S. Perlman, Steven Zimmerly, Huatao Guo, Robert Eskes |
| Alpha-4 integrins mediate lymphocyte attachment and rolling under physiologic flow. | Biological sciences | C. Berlin, R.F. Bargatze, J.J. Campbell, U.H. von Andrian, M.C. Szabo, S.R. Hasslen, R.D. Nelson, E.L. Berg, S.L. Erlandsen, E.C. Butcher |
| Alphavirus and flavivirus glycoproteins: structures and functions. | Biological sciences | Ari Helenius |
| Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. | Biological sciences | Raymond N. DuBois, Masahiko Tsujii |
| Alterations in DNA methylation may play a variety of roles in carcinogenesis. | Biological sciences | Jennifer L. Counts, Jay I. Goodman |
| Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. | Biological sciences | Howard Chen, Carl Nathan, Karen Sokol, John D. MacMicking, Gary Hom, Nicole Chartrin, Daniel S. Fletcher, Myrna Trumbauer, Karla Stevens, Qiao-wen Xie, Nancy Hutchison, John S. Mudgett |
| Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase.(cyclin-dependent kinase (CDK)-activating kinase) | Biological sciences | David O. Morgan, Robert P. Fisher, Pei Jin, Holly M. Chamberlin |
| Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. | Biological sciences | Charles J. Sherr, Frederique Zindy, Dawn E. Quelle, Richard A. Ashmun |
| Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene. | Biological sciences | Owen N. Witte, Douglas C. Saffran, Andrei Goga, Jami McLaughlin, Daniel E.H. Afar |
| A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. | Biological sciences | Ueli Schibler, Erich A. Nigg, Vincent Ossipow, Jean-Pierre Tassan |
| A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the Ikr potassium channel. | Biological sciences | Michael C. Sanguinetti, Mark T. Keating, Mark E. Curran, Changan Jiang |
| A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. | Biological sciences | Eric D. Green, G. Michael Vincent, Katherine W. Timothy, Mark E. Curran, Igor Splawski, Keating Mark T. |
| A molecular pathway determining left-right asymmetry in chick embryogenesis. | Biological sciences | Randy L. Johnson, Claudio D. Stern, Michael Levin, Cliff Tabin, Michael Kuehn |
| Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. | Biological sciences | Robert H. Brown Jr. |
| An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. | Biological sciences | Konrad Basler, Markus Affolter, Denise Nellen, Esther Ruberte, Thomas Marty |
| An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3. | Biological sciences | Ronald A. DePinho, Lynda Chin, Arthur I. Skoultchi, Richard Torres, Nicole Schreiber-Agus, Ken Chen, Govinda Rao, Peter Guida |
| Ancient weapons: NK-lysin is a mammalian homologue to pore forming peptides of a protozoan parasite. | Biological sciences | Matthias Lieppe |
| An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites.(fibroblast growth factor, Caenorhabditis elegans) | Biological sciences | H. Robert Horvitz, Dianna L. De Vore, Michael J. Stern |
| An in vitro assay for Saccharomyces telomerase requires EST1. | Biological sciences | Virginia A. Zakian, Jing-Jer Lin |
| An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. | Biological sciences | Graham Warren, Jan-Michael Peters, Catherine Rabouille, Timothy P. Levine |
| A nodal-related gene defines a physical and functional domain within the Spemann organizer. | Biological sciences | William C. Smith, Richard M. Harland, Roslyn Mckendry, Stephen Ribisi Jr. |
| A nonmammalian homolog of the PAF1 gene (Zellweger syndrome) discovered as a gene involved in caryogamy in the fungus Podospora anserina. | Biological sciences | Marguerite Picard, Denise Zickler, Veronique Berteaux-Lecellier, Catherine Thompson-Coffe, Arlette Panvier-Adoutte, Jean-Marc Simonet |
| A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency. | Biological sciences | Kurt von Figura, Thorsten Selmer, Bernard Schmidt, Arnd Ingendoh |
| A novel family of genes encoding putative pheromone receptors in mammals. | Biological sciences | Catherine Dulac, Richard Axel |
| A novel form of Epstein-Barr virus latency in normal B cells in vivo. | Biological sciences | Bin Yang, David A. Thorley-Lawson, Dorothy H. Crawford, Emily M. Miyashita, Kitty M.C. Lam |
| Antigenic variation in malaria.(Minireview) | Biological sciences | Wilbert Bitter, Fred van Leeuwen, Piet Borst, Richard McCulloch, Gloria Rudenko |
| A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway.(heterogeneous nuclear ribonucleoproteins) | Biological sciences | W. Matthew Michael, Mieyoung Choli, Gideon Dreyfuss |
| An unusual mosaic protein with a protease domain, encoded by the nudel gene, is involved in defining embryonic dorsoventral polarity in Drosophila. | Biological sciences | Carl Hashimoto, Charles C. Hong |
| A perfect vulva every time: gradients and signaling cascades in C. elegans. | Biological sciences | Cynthia Kenyon |
| A phosphotyrosine interaction domain.(Letter to the Editor) | Biological sciences | Peer Bork, Benjamin Margolis |
| Apical, basal, and lateral cues for epithelial polarization.(Minireview) | Biological sciences | Suzanne Eaton, Kai Simons |
| A place in the world for RNA editing. | Biological sciences | James Scott |
| Aplysia CREB2 represses long term facilitation: relief of repression converts transient facilitation into long-term functional and structural change. | Biological sciences | Eric R. Kandel, Dusan Bartsch, Mirella Ghirardi, Kevin A. Karl, Paul A. Skehel, Susan P. Herder, Mary Chen, Craig H. Bailey |
| A pollen tube growth stimulatory glycoprotein is deglycosylated by pollen tubes and displays a glycosylation gradient in the flower. | Biological sciences | Hong Wang, Alice Y. Cheung, Hen-ming Wu |
| A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane. | Biological sciences | Tom A. Rapoport, Berit Jungnickel |
| A prostaglandin J(sub 2) metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. | Biological sciences | Steven A. Kliewer, Timothy M. Willson, James M. Lenhard, Inder Patel, David C. Morris, Jurgen M. Lehmann |
| A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei.(variant surface glycoprotein in Trypanosoma brucei) | Biological sciences | Piet Borst, Gloria Rudenko, Patricia A. Blundell, Anita Dirks-Mulder, Rudo Kieft |
| A role for a small stable RNA in modulating the activity of DNA-binding proteins. | Biological sciences | David I. Friedman, Diane M. Retallack |
| A role for recombination junctions in the segregation of mitochondrial DNA in yeast. | Biological sciences | Daniel Lockshon, Heather E. Lorimer, Stephen G. Zweifel, Lisa L. Freeman-Cook, Bonita J. Brewer, Walton L. Fangman |
| Arrestin binding determines the rate of inactivation of the G protein-coupled receptor rhodopsin in vivo. | Biological sciences | Charles F. Stevens, Rama Ranganathan |
| A second signal recognition event required for translocation into the endoplasmic reticulum. | Biological sciences | Vivian Siegel |
| Assembly of phage Mu transpososomes: cooperative transitions assisted by protein and DNA scaffolds. | Biological sciences | Tania A. Baker, Kiyoshi Mizuuchi, Michiyo Mizuuchi |
| A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding. | Biological sciences | Gray D. Shaw, Raymond T. Camphausen, Dianne Sako, Kenneth M. Comess, Karen M. Barone, Dale A. Cumming |
| Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos.(Caenorhabditis elegans) | Biological sciences | Su Guo, Kenneth J. Kemphues, Bijan Etemad-Moghadam |
| A targeting signal in VAMP regulating transport to synaptic vesicles. | Biological sciences | Regis B. Kelly, Eric Grote, Joe C. Hao, Mark K. Bennett |
| ATM-related genes: what do they tell us about functions of the human gene?(ataxia telangiectasia mutated) | Biological sciences | Virginia A. Zakian |
| Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: structural basis for damaged DNA recognition. | Biological sciences | Shigenori Iwai, Mariko Ariyoshi, Dmitry G. Vassylyev, Kosuke Morikawa, Tatsuki Kashiwagi, Yuriko Mikami, Eiko Ohtsuka |
| ATP-dependent accumulation and inositol trisphosphate- or cyclic ADP-ribose-mediated release of Ca2+ from the nuclear envelope. | Biological sciences | Oleg V. Gerasimenko, Julia V. Gerasimenko, Alexei V. Tepikin, Ole H. Petersen |
| Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme. | Biological sciences | John F. Atkins, Raymond F. Gesteland, Yasuko Murakami, Senya Matsufuji, Shin-ichi Hayashi, Tamiko Matsufuji, Youichi Miyazaki |
| Autosomal dominant and recessive osteochondrodysplasias associated with the COL 11A2 locus. | Biological sciences | George E. Tiller, Hans-Hilger Ropers, Mary B. Goldring, Miikka Vikkula, Edwin C.M. Mariman, Vincent C.H. Lui, Natalia I. Zhidkova, Sylvia E.C. van Beersum, Maarten C. de Waal Malefijt, Frank H.J. van den Hoogen |
| Axis formation in plant embryogenesis: cues and clues. | Biological sciences | Gerd Jurgens |
| Axon guidance: a compelling case for repelling growth cones. | Biological sciences | Jane Dodd, Anita Schuchardt |
| Axon guidance molecules. (Review) | Biological sciences | Roger Keynes, Geoffrey M.W. Cook |
| Axon membrane flows from the growth cone to the cell body. | Biological sciences | Michael P. Sheetz, Jianwu Dai |
| B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. | Biological sciences | Scott S. Zamvil, Howard L. Weiner, Raymond A. Sobel, Vijay K. Kuchroo, Ann M. Ranger, Julia A. Brown, Mercy Prabhu Das, Nasrin Nabavi, Laurie H. Gilmcher |
| Bad, a heterodimeric partner for Bcl-x(L) and Bcl-2, displaces Bax and promotes cell death. | Biological sciences | Stanley J. Korsmeyer, Craig B. Thompson, Jiping Zha, Elizabeth Yang, Jennifer Jockel, Lawrence H. Boise |
| Basic FGF as an inducer of anteroposterior neural pattern.(fibroblast growth factor) | Biological sciences | Tabitha Doniach |
| Beta-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. | Biological sciences | Hui Zheng, David W. Smith, Sangram S. Sisodia, Gerard R. Dawson, Minghao Jiang, Myrna E. Trumbauer, Dalip J. S. Sirinathsinghji, Ruth Hopkins, Robert P. Heavens, Susan Boyce, Michael W. Cnner, Karla A. Stevens, Hilda H. Slunt, Howard Y. Chen, Lex. H.T. van der Ploeg |
| Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein.(neuronal adaptin-like protein) | Biological sciences | Robert B. Darnell, Lori S. Newman, Hirotaka J. Okano, Matthew O. McKeever |
| Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in Drosophila embryos. | Biological sciences | Robin P. Wharton, Yoshihiko Murata |
| Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. | Biological sciences | Robert Tjian, Jin-Long Chen, C.Peter Verrijzer, Kyoko Yokomori |
| Branch migration during homologous recombination: assembly of a RuvAB-Holliday junction complex in vitro. | Biological sciences | Stephen C. West, Kevin Hiom |
| Calcineurin associated with the inositol 1,4,5-triphosphate receptor-FKBP12 complex modulates Ca2+ flux. | Biological sciences | Solomon H. Synder, Gabriele V. Ronnett, Joseph P. Steiner, A. Jane Roskams, Andrew M. Cameron, Siraj M. Ali |
| Calcium ions as extracellular messengers. | Biological sciences | Edward M. Brown, Peter M. Vassilev, Steven C. Hebert |
| Calcium signaling. | Biological sciences | David E. Clapham |
| Calreticulin inhibits repetitive intracellular Ca2+ waves. | Biological sciences | Patricia Camacho, James D. Lechleiter |
| CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP.(Ca2+/calmodulin-dependent protein kinase II, long-term depression, long-term potential) | Biological sciences | Eric R. Kandel, Jian Wang, Mark Mayford, Thomas J. O'Dell |
| cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs. | Biological sciences | Gerald M. Rubin, Duojia Pan |
| Can Hsp70 proteins act as force-generating motors? | Biological sciences | Benjamin S. Glick |
| Can the immune response control HIV infection? | Biological sciences | William E. Paul |
| Capping protein levels influence actin assembly and cell motility in dictyostelium. | Biological sciences | John A. Cooper, Indira Reddy, Christopher Hug, Patrick Y. Jay, James G. McNall, Paul C. Bridgman, Eliott L. Elson |
| CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. | Biological sciences | Stuart Tugendreich, Philip Hieter, John Tomkiel, William Earnshaw |
| Cell-cell signaling, microtubules, and the loss of symmetry in the Drosophila oocyte. | Biological sciences | Ruth Lehmann |
| Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. | Biological sciences | Sean B. Carroll, Jaeseob Kim, Kenneth D. Irvine |
| Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. | Biological sciences | Zvi Fuks, Richard Kolesnick, Adriana Haimovitz-Friedman, Ron Bose, Marcel Verheij, Kathleen Scotto |
| C-fos is required for malignant progression of skin tumors. | Biological sciences | Bruce M. Spiegelman, Enrique Saez, Elisabetta Mueller, Susan E. Rutberg, Heather Oppenheim, Jennifer Smoluk, Stuart H. Yuspa |
| CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. | Biological sciences | Garry R. Cutting, William B. Guggino, Erik M. Schwiebert, Marie E. Egan, Tae-Ho Hwang, Stephanie B. Fulmer, Sandra S. Allen |
| Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.(recombination-activating genes) | Biological sciences | Martin Gellert, Charles Romeo, Marjorie A. Oettinger, Christina A. Cuomo, J. Fraser McBlane, Dale A. Ramsden, Dik C. Van Gent |
| Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis. | Biological sciences | Susan K. McConnell, Anjen Chenn |
| Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. | Biological sciences | John C. Reed, Takaaki Sato, Shinichi Takayama, Stanislaw Krajewski, Kristine Kochel, Shinji Irie, Juan A. Millan |
| Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function. | Biological sciences | Guoping Feng, Peter Deak, Linda M. Hall, Maninder Chopra |
| Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. | Biological sciences | Karl Tryggvason, Irma Thesleff, Juha Tuukkanen, Outi Elomaa, Maarit Kangas, Carin Sahlberg, Raija Sormunen, Annikki Liakka, Georg Kraal |
| Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes. | Biological sciences | Russell J. Howard, Michael Feldman, Dror I. Baruch, Brittan L. Pasloske, Hardeep B. Singh, Xiahui Bi, Xin C. Ma, Theodore F. Taraschi |
| Comparison of recombination in vitro and in E. coli cells: measure of the effective concentration of DNA in vivo. | Biological sciences | Nicholas R. Cozzarelli, Emily R. Hildebrandt |
| Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. | Biological sciences | Hwai-Jong Cheng, John G. Flanagan, Masaru Nakamoto, Andrew D. Bergemann |
| Complexins: cytosolic proteins that regulate SNAP receptor function.(soluble N-ethylmaleimide-sensitive factor attachment proteins) | Biological sciences | Thomas C. Sudhof, Harvey T. McMahon, Markus Missler, Cai Li |
| Conformational states of CFTR associated with channel gating: the role of ATP binding and hydrolysis.(cystic fibrosis transmembrane conductance regulator) | Biological sciences | Ron R. Kopito, Kevin L. Gunderson |
| Contact with a component of the polymerase II holoenzyme suffices for gene activation. | Biological sciences | Natasha Simkovich, Susan Farrell, Mark Ptashne, Pamela Reinagel, Alcide Barberis, Joseph Pearlberg, Cynthia Bamdad, George Sigal |
| Contenders in FasL/TNF death signaling. (Fas ligand; tumor necrosis factors) | Biological sciences | James N. Ihle, John L. Cleveland |
| Control of Drosophila photoreceptor cell fates by phyllopod, a novel nuclear protein acting downstream of the Raf kinase. | Biological sciences | Barry J. Dickson, Ernst Hafen, Maria Dominguez, Alexandra van der Straten |
| Control of neuronal diversity by the floor plate: contact-mediated induction of midbrain dopaminergic neurons. | Biological sciences | Marc Tessier-Lavigne, Arnon Rosenthal, Mary Hynes, Kris Poulsen |
| Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins.(myocyte enhancer factor-2, basic helix-loop-helix) | Biological sciences | Eric N. Olson, Jeffery D. Molkentin, James F. Martin, Brian L. Black |
| COPI and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. | Biological sciences | Mylene Amherdt, Mariella Ravazzola, Alain Perrelet, Lelio Orci, Midori Hosobuchi, Randy Schekman, Sebastian Y. Bednarek |
| cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila.(cornichon gene and the epidermal growth factor) | Biological sciences | Trudi Schupbach, Siegfried Roth, F. Shira Neuman-Silberberg, Gail Barcelo |
| Coronin involved in phagocytosis: dynamics of particle-induced relocalization visualized by a green fluorescent protein tag. | Biological sciences | John Murphy, Markus Maniak, Robert Rauchenberger, Richard Albrecht, Gunther Gerisch |
| Coupling between transcription termination and RNA polymerase inchworming. | Biological sciences | Alex Goldfarb, Evgeny Nudler, Mikhail Kashlev, Vadim Nikiforov |
| CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila.(cAMP-reponsive element-binding protein) | Biological sciences | J.C.P. Yin, M. Del Vecchio, H. Zhou, T. Tully |
| Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis. | Biological sciences | Clifford D. Mol, John A. Tainer, Andrew S. Arvai, Geir Slupphaug, Bodil Kavli, Ingrun Alseth, Hans E. Krokan |
| Crystal structure of a paired domain-DNA complex at 2.5 angstrom resolution reveals structural basis for Pax developmental mutations. | Biological sciences | Wenqing Xu, Claude Desplan, Carl O. Pabo, Mark A. Rould, Susie Jun |
| Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA. | Biological sciences | Clifford D. Mol, Andrew S. Arvai, Geir Slupphaug, Bodil Kavli, Hans E. Krokan, Russell J. Sanderson, Dale W. Mosbaugh, John A. Trainer |
| Crystal structure of the A Domain from the alpha subunit of integrin CR3 (CD11b/CD18). | Biological sciences | M. Amin Arnaout, Jie-Oh Lee, Robert Liddington, Philippe Rieu |
| Crystal structure of the cys2 activator-binding domain of protein kinase C-delta in complex with phorbol ester. | Biological sciences | James H. Hurley, Peter M. Blumberg, Marcelo G. Kazanietz, Gongyi Zhang |
| Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein EBNA1.(Epstein-Barr nuclear antigen 1) | Biological sciences | Richard A. Pfuetzner, Alexey Bochkarev, Lori Frappier, Aled M. Edwards, Jean A. Barwell, William Furey Jr. |
| Crystal structure of the replication terminator protein from B. subtilis at 2.6 angstrom. | Biological sciences | Stephen W. White, Deepak Bastia, Dirksen Eli Bussiere |
| Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site. | Biological sciences | Wei Yang, Thomas A. Steitz |
| Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. | Biological sciences | David M. Livingston, Wilhelm Krek, Gangfeng Xu |
| Cyclin D1 provides a link between development and oncogenesis in the retina and breast. | Biological sciences | Robert A. Weinberg, Stephen J. Elledge, Roderick T. Bronson, Sandra Z. Haslam, Joana Liu Donaher, Piotr Sicinski, Amin Fazeli, Humphrey Gardner, Tiansen Li, Susan B. Parker |
| Cyclin ubiquitination: the destructive end of mitosis. | Biological sciences | Andrew Murray |
| Cytoplasmic coat proteins involved in endosome function. | Biological sciences | Ira Mellman, David Sheff, J. Andrew Whitney, Marie Gomez, Thomas E. Kreis |
| Decoding of cytosolic calcium oscillations in the mitochondria. | Biological sciences | Andrew P. Thomas, Gyorgy Hajnoczky, Lawrence Robb-Gaspers, Michele B. Seitz |
| Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. | Biological sciences | Frederick W. Alt, Stephen P. Jackson, Tanya M. Gottlieb, Graeme C.M. Smith, Guillermo E. Taccioli, Penny A. Jeggo, Tracy Blunt, Nicholas J. Finnie, Jocelyne Demengeot, Ryushin Mizuta, A.J. Varghese |
| Degradation of CFTR by the ubiquitin-proteasome pathway.(cystic fibrosis transmembrane conductance regulator) | Biological sciences | Satoshi Omura, Ron R. Kopito, Cristina L. Ward |
| Degradation of mRNA in eukaryotes. | Biological sciences | Roy Parker, Clare A. Beelman |
| Dendritic cell progenitor is transformed by a conditional v-Rel estrogen receptor fusion protein v-RelER. | Biological sciences | Heinz Schwarz, Guido Boehmelt, Jaime Madruga, Petra Dorfler, Karoline Briegel, Paula J. Enrietto, Martin Zenke |
| Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. | Biological sciences | Roger D. Kornberg, Errol C. Friedberg, David A. Bushnell, Jesper Q. Svejstrup, Zhigang Wang, William J. Feaver, Xiahua Wu, Thomas F. Donahue |
| Different levels of the C. elegans growth factor LIN-3 promote distinct vulval precursor fates. | Biological sciences | Paul W. Sternberg, Thomas R. Clandinin, Wendy S. Katz, Russel J. Hill |
| Different requirements for NSF, SNAP, and Rab proteins in apical and basolateral transport in MDCK cells. | Biological sciences | Elina Ikonen, Kai Simons, Cesare Montecucco, Mitsuo Tagaya, Oliver Ullrich |
| Dimerization of cell surface receptors in signal transduction. | Biological sciences | Carl-Henrik Heldin |
| Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex. | Biological sciences | Timothy I. Meier, Robert Landick, Guohua Feng, Daguang Wang, Cathleen L. Chan, Donna N. Lee |
| Displacement of sequence-specific transcription factors from mitotic chromatin. | Biological sciences | Carl Wu, Keiko Ozato, Marian A. Martinez-Balbas, Anup Dey, Sridhar K. Rabindran |
| Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. | Biological sciences | C.C. Morton, H.R. Ashar, M. Schoenberg Fejzo, A. Tkachenko, X. Zhou, J.A. Fletcher, S. Weremowicz, K. Chada |
| Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. | Biological sciences | Peter Gruss, Vasanta Subramanian, Barbara I. Meyer |
| Dissecting RNA-protein interactions: RNA-RNA recognition by Rop. | Biological sciences | Paul F. Predki, L. Mike Nayak, Morris B.C. Gottlieb, Lynne Regan |
| Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? | Biological sciences | Craig B. Thompson |
| Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. | Biological sciences | Cornelia I. Bargmann, Emily R. Troemel, Joseph H. Chou, Noelle D. Dwyer, Heather A. Colbert |
| DNA binding and meiotic chromosomal localization of the Drosophila nod kinesin-like protein. | Biological sciences | R. Scott Hawley, Lawrence S.B. Goldstein, Nelson R. Barton, Katayoun Afshar |
| DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. | Biological sciences | Hong Zhang, Stephen P. Jackson, Carl W. Anderson, Nullin Divecha, Graeme C.M. Smith, Katharine O. Hartley, David Gell, Margery A. Connelly, Arie Admon, Susan P. Lees-Miller |
| DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint. | Biological sciences | Stephen J. Elledge, Zheng Zhou, Tony A. Navas |
| DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA. | Biological sciences | Patrick Sung, Donald L. Robberson |
| DNA transposition: from a black box to a color monitor. | Biological sciences | Nigel D.F. Grindley, Andres E. Leschziner |
| Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. | Biological sciences | Stephen E. Straus, Warren Strober, Michael J. Lenardo, Galen H. Fisher, Jennifer M. Puck, Albert Y. Lin, Fredric J. Rosenberg, Janet K. Dale, Lindsay A. Middelton |
| Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. | Biological sciences | Richard D. Palmiter, Qun-Yong Zhou |
| Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm.(bone morphogenetic protein) | Biological sciences | Thomas M. Jessell, Karel F. Liem Jr., Gabi Tremml, Henk Roelink |
| Drosophila dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF-beta receptor family. (transforming growth factor) | Biological sciences | Jeffrey L. Wrana, Joan Massague, Michael B. O'Connor, William M. Gelbart, Anthea Letsou, Kavita Arora, Joumana Jamal, F. Michael Hoffmann, Karl Simin, Vern Twombly, Karen Staehling-Hampton |
| Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death. | Biological sciences | Gerald M. Rubin, Bruce A. Hay, David A. Wassarman |
| E. coli SeqA protein binds oriC in two different methyl-modulated reactions appropriate to its roles in DNA replication initiation and origin sequestration.(Escherichia coli) | Biological sciences | Min Lu, Nancy Kleckner, Steven Slater, Erik Boye, Sture Wold, Kirsten Skarstad |
| Ectopic expression of the flagellar regulon alters development of the Bordetella-host interaction. | Biological sciences | Jeff F. Miller, Brian J. Akerley, Peggy A. Cotter |
| Enhanced HIV-1 replication in V-beta-12 T cells due to human cytomegalovirus in monocytes: evidence for a putative herpesvirus superantigen. | Biological sciences | Adam S. Asch, Melissa Pope, Dana Dobrescu, Bogdan Ursea, David N. Posnett |
| Enigma variations: protein mediators of membrane fusion. | Biological sciences | Ira Mellman |
| Epigenetic control of an endogenous gene family is revealed by a novel blue fluorescent mutant of Arabidopsis. | Biological sciences | Judith Bender, Gerald R. Fink |
| Escape from "horror autotoxicus": pathogenesis and treatment of autoimmune disease. | Biological sciences | Lawrence Steinman |
| Evidence for a NIMA-like mitotic pathway in vertebrate cells. | Biological sciences | Tony Hunter, Kun Ping Lu |
| Evidence for positional differentiation of prestalk cells and for a morphogenetic gradient in Dictyostelium. | Biological sciences | Tomoaki Abe, Jeffrey Williams, Anne Early |
| Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site. (apolipoprotein B) | Biological sciences | James Scott, Shoumo Bhattacharya, Dipti Patel, Naveenan Navaratnam, Takahiro Fujino, Adam L. Jarmuz |
| Expression cloning of Siamosis, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. | Biological sciences | Patrick Lemaire, J.B. Gurdon, Nigel Garrett |
| Expression of crumbs confers apical character on plasma membrane domains of ectodermalpithelia of Drosophila. | Biological sciences | Elisabeth Knust, Andreas Wodarz, Uwe Hinz, Martin Engelbert |
| Expression of Msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila.(male-specific lethal-2) | Biological sciences | Richard L. Kelley, Mitzi I. Kuroda, Ron Richman, Irina Solovyeva, Laura M. Lyman, Victor Solovyev |
| Extracellular signal protein triggering the proteolytic activation of a developmental transcription factor in B. subtilis. | Biological sciences | Richard Losick, Patrick Stragier, Antje E.M. Hofmeister, Arturo Londono-Vallejo, Elizabeth Harry |
| FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. | Biological sciences | Arul M. Chinnaiyan, Karen O'Rourke, Vishva M. Dixit, Muneesh Tewari |
| Fibroblast growth factors induce additional limb development from the flank of chick embryos. | Biological sciences | Martin J. Cohn, Cheryll Tickle, John K. Heath, Juan Carlos Izpisua-Belmonte, Helen Abud |
| Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. | Biological sciences | Y. Tanabe, T.M. Jessell, H. Roelink, J.A. Porter, C. Chiang, D.T. Chang, P.A. Beachy |
| From embryogenesis to metamorphosis: The regulation and function of Drosophila nuclear receptor superfamily members. | Biological sciences | Carl S. Thummel |
| FtsZ, a prokaryotic homolog of tubulin? | Biological sciences | Harold P. Erickson |
| Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development. | Biological sciences | Daniel Kalderon, Willis Li, Johanna Talavera Ohlmeyer, Mary Ellen Lane |
| Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor.(burst-forming unit-erythroid, colony-forming unit-erythroid) | Biological sciences | Harvey F. Lodish, Hong Wu, Rudolf Jaenisch, Xin Liu |
| Genes for SMA: multum in parvo. | Biological sciences | Benjamin Lewin |
| Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. | Biological sciences | Kim Nasmyth, Stefan Irniger, Simonetta Piatti, Christine Michaelis |
| Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration. | Biological sciences | Elaine Fuchs, Linda Degenstein, Lifei Guo, James Dowling, Qian-Chun Yu, Robert Wollmann, Benjamin Perman |
| Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission. | Biological sciences | Hugo J. Bellen, Kendal Broadie, Mark S. Perin, Karen L. Schulze |
| Glial cells missing: a binary switch between neuronal and glial determination in Drosophila. | Biological sciences | Yoshiki Hotta, Toshihiko Hosoya, Kazunaga Takizawa, Koushi Nitta |
| Glial cells missing: a genetic switch that controls glial versus neuronal fate. | Biological sciences | Corey S. Goodman, Richard D. Fetter, Guy Tear, Bradley W. Jones |
| Gliotactin, a novel transmembrane protein on peripheral glia, is required to form the blood-nerve barrier in Drosophila. | Biological sciences | Corey S. Goodman, Richard D. Fetter, Kendal Broadie, Vanessa J. Auld |
| Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum. | Biological sciences | Ari Helenius, Daniel N. Hebert, Brigitte Foellmer |
| Glycogen synthase kinase 3 regulates cell fate in Dictyostelium. | Biological sciences | A.J. Harwood, S.E. Plyte, J. Woodgett, H. Strutt, R.R. Kay |
| Group II intron mobility occurs by target DNA-primed reverse transcription. | Biological sciences | Alan M. Lambowitz, Philip S. Perlman, Steven Zimmerly, Huatao Guo |
| GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more. | Biological sciences | Lisa Stowers, John Chant |
| Hairy and emc negatively regulate morphogenetic furrow progression in the Drosophila eye. | Biological sciences | Sean B. Carroll, Nadean L. Brown, Carol A. Sattler, Stephen W. Paddock |
| Harold Weintraub (1945-1995).(Obituary) | Biological sciences | Richard Axel, Tom Maniatis |
| Hedgehog and beyond. (Hedgehog protein) | Biological sciences | Norbert Perrimon |
| Hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.(mitogen-activated protein) | Biological sciences | Stephane Noselli, Bruno Glise, Henry Bourbon |
| Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. | Biological sciences | Arlene H. Sharpe, Thomas P. Stossel, John H. Hartwig, David J. Kwiatkowski, Walter Witke, Toshifumi Azuma |
| Heterotrimeric G proteins: organizers of transmembrane signals. | Biological sciences | Eva J. Neer |
| High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA. | Biological sciences | David S. Wilson, Claude Desplan, John Kuriyan, Guenther Brian |
| Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle. | Biological sciences | Jorg Hohfeld, Yasufumi Minami, Franz-Ulrich Hartl |
| Histidine phosphorylation of P-selection upon stimulation of human platelets: a novel pathway for activation-dependent signal transduction. | Biological sciences | Bruce Furie, Barbara C. Furie, Colleen Sweeney Crovello |
| Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. | Biological sciences | Susan M. Gasser, Michael Grunstein, Thierry Laroche, Andreas Hecht, Sabine Strahl-Bolsinger |
| HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator. | Biological sciences | Didier Trono, Simon Swingler, Philippe Gallay, Christopher Aiken |
| HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase.(human immunodeficiency virus) | Biological sciences | Didier Trono, Simon Swingler, Frederic Bushman, Philippe Gallay, Jinping Song |
| HLA-DM induces CLIP dissociation from MHC class II alpha-beta dimers and facilitates peptide loading.((human leukocyte antigen DM) (class II-associated invariant chain peptides) (major histocompatibility complex)) | Biological sciences | Peter Cresswell, Lisa K. Denzin |
| How proteins penetrate peroxisomes. | Biological sciences | Suresh Subramani, Richard A. Rachubinski |
| Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process. | Biological sciences | Claude-Agnes Reynaud, Corinne Garcia, Wayne R. Hein, Jean-Claude Weill |
| Identification and characterization of a spinal muscular atrophy-determining gene. | Biological sciences | Olivier Clermont, Massimo Zeviani, Daniel Cohen, Jean Weissenbach, Philippe Millasseau, Denis Le Paslier, Arnold Munnich, Louis Viollet, Suzie Lefebvre, Lydie Burglen, Sophie Reboullet, Philippe Burlet, Bernard Benichou, Corinne Cruaud, Jean Frezal, Judith Melki |
| Identification and expression cloning of a leptin receptor, OB-R. | Biological sciences | Louis A. Tartaglia, Elizabeth A. Woolf, Marlene Dembski, Xun Weng, Nanhua Deng, Janice Culpepper, Rene Devos, Grayson J. Richards, L. Arthur Campfield, Frederick T. Clark, Jim Deeds, Craig Muir, Sean Sanker, Ann Moriarty, Karen J. Moore, John S. Smutko, Gail G. Mays, Cheryl A. Monroe, Robert I. Tepper |
| Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkey. | Biological sciences | Ronald C. Desrosiers, Andrew A. Lackner, Jae U. Jung, Zhenjian Du, Sabine M. Lang, Vito G. Sasseville, Petr O. llyinskii, Muthiah D. Daniel |
| Identification of an ER retrieval signal in a retroviral glycoprotein.(endoplasmic reticulum)(Letter to the Editor) | Biological sciences | G. Wang, P.A. Goepfert, M.J. Mulligan |
| Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins. | Biological sciences | Bryan R. Cullen, Hal P. Bogerd, Robert A. Fridell, Steven Madore |
| Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast. | Biological sciences | Michael Rosbash, Francoise Stutz, Megan Neville |
| Identification of a nuclear receptor that is activated by farnesol metabolites. | Biological sciences | Ronald M. Evans, Daniel J. Noonan, David J. Bradley, Anthony E. Oro, Thomas Perlmann, Barry M. Forman, Elizabeth Goode, Jasmine Chen, Leo T. Burka, Trevor McMorris, William W. Lamph, Cary Weinberger |
| Identification of a signal for rapid export of proteins from the nucleus. | Biological sciences | Susan S. Taylor, Roger Y. Tsien, Wei Wen, Judy L. Meinkoth |
| Identification of domains conferring G protein regulation on inward rectifier potassium channels. | Biological sciences | Maya T. Kunkel, Ernest G. Peralta |
| Identification of double Holliday junctions as intermediates in meiotic recombination. | Biological sciences | Nancy Kleckner, Anthony Schwacha |
| Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor. | Biological sciences | Hiroshi Nojima, Yumiko Kubota, Satoru Mimura, Shin-ichi Nishimoto, Haruhiko Takisaw |
| "If the shoe fits": clues on structural recognition of DNA damage.(minireview) | Biological sciences | James E. Cleaver, Susan K. Layher |
| I-kappa-B-beta regulates the persistent response in a biphasic activation of NF-kappa-B. | Biological sciences | Hediye Erdjument-Bromage, Paul Tempst, Sankar Ghosh, James E. Thompson, Roderick J. Phillips |
| Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC-gamma mutant mice.(protein kinase C-gamma) | Biological sciences | Susumu Tonegawa, Lu Chen, Shaowen Bao, Richard F. Thompson, Asa Abeliovich, Masanobu Kano, Kouichi Hashimoto, Chong Chen, Jeansok J. Kim |
| Impaired synapse elimination during cerebral development in PKC-gamma mutant mice.(protein kinase C-gamma) | Biological sciences | Susumu Tonegawa, Asa Abeliovich, Yoshiro Inoue, Masanobu Kano, Kouichi Hashimoto, Chong Chen, Atsu Aiba, Hideo Kurihara, Masahiko Watanabe |
| Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in gluRdelta2 mutant mice. | Biological sciences | Takeshi Yagi, Masayoshi Mishina, Shinichi Aizawa, Tatsuya Kutsuwada, Chitoshi Takayama, Yoshiro Inoue, Nobuko Kashiwabuchi, Kazutaka Ikeda, Tomoo Hirano, Katsuei Shibuki, Youngnam Kang, Kazuaki Araki |
| Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of theta frequency.(Ca2+/calmodulin-dependent protein kinase II, long-term potential) | Biological sciences | Eric R. Kandel, Robert D. Hawkins, Mark Mayford, Mary Elizabeth Bach, Mona Osman |
| Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. | Biological sciences | Anton Berns, Miroslav Radman, Marleen Dekker, Hein te Riele, Niels de Wind |
| Increased neutrophil respiratory burst in bcr-null mutants. | Biological sciences | Thomas Coates, Nora Heisterkamp, John Groffen, Vesa Kaartinen, Jan Willem Voncken, Hermien van Schaick, Kathleen Deemer, Benjamin Landing, Paul Pattengale, Oilvier Dorseuil, Gary M. Bokoch |
| Induction of anti-self-immunity to cure cancer. | Biological sciences | Eli E. Sercarz, Navreet K. Nanda |
| Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb. | Biological sciences | Thomas M. Jessell, Cliff Tabin, Craig Nelson, Robert D. Riddle, Monica Ensini, Tammy Tsuchida |
| Initiation of V(D)J recombination in a cell-free system. | Biological sciences | Martin Gellert, Dik C. van Gent, J. Fraser McBlane, Dale A. Ramsden, Moshe J. Sadofsky, Joanne E. Hesse |
| Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix. | Biological sciences | John A. McDonald, Chuanyue Wu, Virginia M. Keivens, Timothy E. O'Toole, Mark H. Ginsberg |
| Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. | Biological sciences | Lee Niswander, Yingzi Yang |
| Interactions between the nod+ kinesin-like gene and extracentromeric sequences are required for transmission of a Drosophila minichromosome. | Biological sciences | Gary H. Karpen, Terence D. Murphy |
| Interspecies gene exchange in bacteria: the role of SOS and mismatch repair systems in evolution of species. | Biological sciences | Miroslav Radman, Ivan Matic, Christiane Rayssiguier |
| In vitro guidance of retinal ganglion cell axons by RAGs, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases. | Biological sciences | Uwe Drescher, Claus Kremoser, Claudia Handwerker, Jurgen Loschinger, Masaharu Noda, Friedrich Bonhoeffer |
| Isolation of a novel gene underlying Batten disease, CLN3. | Biological sciences | |
| ISWI, a member of the SW12/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodelling factor.(imitation switch protein) | Biological sciences | Carl Wu, Toshio Tsukiyama, Carla Daniel, John Tamkun |
| Jagged: a mammalian ligand that activates Notch1. | Biological sciences | Gerry Weinmaster, Carrie J. Shawber, Claire E. Lindsell, Jim Boulter |
| JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye. | Biological sciences | Marek Mlodzik, Dirk Bohmann, Mathias Treier |
| KSR: A novel player in the RAS pathway.(kinase suppressor of RAS) | Biological sciences | Julian Downward |
| KSR, a novel protein kinase required for RAS signal transduction.(kinase suppressor of RAS) | Biological sciences | Gerald M. Rubin, Marc Therrien, Henry C. Chang, Noah M. Solomon, Felix D. Karim, David A. Wassarman |
| LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. | Biological sciences | Rudolph E. Tanzi, Robert D. Moir, Bradley T. Hyman, Ashley I. Bush, G. William Rebeck, Maria Z. Kounnas, W. Scott Argraves, Dudley K. Strickland |
| Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript. | Biological sciences | Jennifer J. Loros, Jay C. Dunlap, Susan K. Crosthwaite |
| Linker histones are not essential and affect chromatin condensation in vivo. | Biological sciences | Xuetong Shen, Martin A. Gorovsky, Lanlan Yu, Joyce W. Weir |
| Localization of centromere function in a Drosophila minichromosome. | Biological sciences | Gary H. Karpen, Terence D. Murphy |
| Long-range interaction between two promoters: activation of the leu-500 promoter by a distant upstream promoter. | Biological sciences | Ming Fang, Hai-Young Wu, Jianyou Tan |
| Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signalling pathway. | Biological sciences | Marc Tessier-Lavigne, Philip A. Beachy, Jeffery A. Porter, Chen-Ming Fan, Chin Chiang, David T. Chang |
| Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons. | Biological sciences | Nancy A. Jenkins, Neal G. Copeland, Luis F. Parada, Camilynn I. Brannan, Kristine S. Vogel |
| Low pH induces swiveling of the glycoprotein heterodimers in the Semliki Forest virus spike complex. | Biological sciences | Sarah J. Butcher, Stephen D. Fuller, John A. Berriman, Brent E. Gowen |
| Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. | Biological sciences | Donald E. Ayer, Robert N. Eisenman, Quentin A. Lawrence |
| Making the connection: cytoskeletal rearrangements during growth cone guidance. (Review) | Biological sciences | Elly Tanaka, James Sabry |
| Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. | Biological sciences | Richard A. Flavell, Jian Yu, Lin Zhang, Terry Ashley, Sean M. Baker, C. Eric Bronner, Annemieke W. Plug, Merrilee Robatzek, Gwynedd Warren, Eileen A. Elliott, Norman Arnheim, R.Michael Liskay |
| Mammalian DNA nucleotide excision repair reconstituted with purified protein components. | Biological sciences | Ulrich Hubscher, Jean-Marc Egly, Richard D. Wood, Abdelilah Aboussekhra, Maureen Biggerstaff, Mahmud K.K. Shivji, Juhani A. Vilpo, Vincent Moncollin, Vladimir N. Podust, Miroslava Protic |
| MAP kinase pathways in yeast: for mating and more. | Biological sciences | Ira Herskowitz |
| Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. | Biological sciences | James E. Darnell Jr., Zilong Wen, Zhong Zhong |
| Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel. | Biological sciences | Margaret P. Price, Michael J. Welsh, Christopher M. Adams, Peter M. Snyder, Fiona J. McDonald, Kenneth A. Volk, Bernhardt G. Zeiher, John B. Stokes |
| Mechanism of corepressor-mediated specific DNA binding by the purine repressor. | Biological sciences | Richard G. Brennan, Maria A. Schumacher, Kang Yell Choi, Fu Lu, Howard Zalkin |
| Mechanism of GroEL action: productive release of polypeptide from a sequestered position under GroES. | Biological sciences | Jonathan S. Weissman, Helen R. Saibil, Arthur L. Horwich, Wayne A. Fenton, Yechezkel Kashi, Corinne M. Hohl, Oleg Kovalenko, Shaoxia Chen, Kerstin Braig |
| Mechanisms of Drosophila retinal morphogenesis: the virtues of being progressive. | Biological sciences | Kevin Moses, Ulrike Heberlein |
| Mei-S332, a Drosophila protein required for sister-chromatid cohesion, can localize to meiotic centromere regions. | Biological sciences | Terry L. Orr-Weaver, Anne W. Kerrebrock, Daniel P. Moore, Jim S. Wu |
| Melatonin madness.(melatonin not a wonder drug) | Biological sciences | Steven M. Reppert, David R. Weaver |
| Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes.(endoplasmic reticulum) | Biological sciences | Randy Schekman, Martin Latterich, Kai-Uwe Frohlich |
| Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. | Biological sciences | Ping Li, Jochen Salfeld, Hamish Allen, Subhashis Banerjee, Simon Franklin, Linda Herzog, Cynthia Johnston, Jack McDowell, Michael Paskind, Laura Rodman |
| Mice lacking p21(superCIP1/WAF1) undergo normal development, but are defective in G1 checkpoint control. | Biological sciences | Philip Leder, J. Wade Harper, Pumin Zhang, Chuxia Deng, Stephan J. Elledge |
| Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. | Biological sciences | George D. Yancopoulos, Li Pan, Joyce McClain, Thomas M. DeChiara, Nancy Y. Ip, Neil Stahl, William T. Poueymirou, Ann Acheson, Joanne C. Conover, Richard Vejsada, Chitra Suri, Beth Friedman, Ann Kato |
| Mitochondrial protein import: reversible binding of the presequence at the trans side of the outer membrane drives partial translocation and unfolding. | Biological sciences | Walter Neupert, Andreas Mayer, Roland Lill |
| Modular binding domains in signal transduction proteins. | Biological sciences | David Baltimore, Ruibao Ren, George B. Cohen |
| Molecular basis of human 46X, Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex. | Biological sciences | G. Marius Clore, Angela M. Gronenborn, Milton H. Werner, Jeffrey R. Huth |
| Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. | Biological sciences | Kai W. Wucherpfennig, Jack L. Strominger |
| Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor. | Biological sciences | J.M. White, A. Sonnenberg, E.A.C. Almeida, A.-P.J. Huovila, A.E. Sutherland, L.E. Stephens, P.G. Calarco, L.M. Shaw, A.M. Mercurio, P. Primakoff, D.G. Myles |
| MSX1 inhibits MyoD expression in fibroblast x 10T1/2 cell hybrids. | Biological sciences | Kening Song, David Sassoon, David J. Goldhamer, Paul Woloshin, Catherine Degnin, Ann McNeill Killary, Mathew J. Thayer |
| Multiallelic recognition: nonself-dependent dimerization of the bE and bW homeodomain proteins in Ustilago maydis. | Biological sciences | Michael Bolker, Regine Kahmann, Jorg Kamper, Michael Reichmann, Tina Romeis |
| Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa-B/Rel family. | Biological sciences | Sergio A. Lira, Falk Weih, Daniel Carrasco, Stephen K. Durham, Debra S. Barton, Cheryl A. Rizzo, Rolf-Peter Ryseck, Rodrigo Bravo |
| Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. | Biological sciences | Steven A. Stacker, Ashley R. Dunn, Dianne Grail, Margaret L. Hibbs, David M. Tarlinton, Jane Armes, George Hodgson, Rosemarie Maglitto |
| Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.(cystic fibrosis transmembrane conductance regulator) | Biological sciences | Alfred L. Goldberg, John R. Riordan, Timothy J. Jensen, Melinda A. Loo, Steven Pind, David B. Wiliams |
| Multiple Ras functions can contribute to mammalian cell transformation. | Biological sciences | Michael Karin, Linda Van Aelst, Michael Wigler, Michael A. White, Charles Nicolette, Audrey Minden, Anthony Polverino |
| Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure. | Biological sciences | Albert De la Chapelle, Kristiina Aittomaki, Jose Luis Dieguez Lucena, Pirjo Pakarinen, Pertii Sistonen, Juha Tapanainen, Jorg Gromoll, Riitta Kaskikari, Eeva-Marja Sankila, Heikki Lehvaslaiho, Armando Reyes Engel, Eberhard Nieschlang, Ilpo Huhtaniemi |
| Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. | Biological sciences | Brian K. Kennedy, Nicanor R. Austriaco Jr., Jisi Zhang, Leonard Guarante |
| Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome). | Biological sciences | Douglas R. Higgs, Richard J. Gibbons, David J. Picketts, Laurent Villard |
| Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. | Biological sciences | David M. Glover, Mark H. Leibowitz, Doris A. McLean, Huw Parry |
| Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A. | Biological sciences | Charles E. Jackson, Daniel Cohen, Michel Fardeau, Jacques S. Beckmann, Mayana Zatz, Isabelle Richard, Odile Broux, Valerie Allamand, Francoise Fougerousse, Nuchanard Chiannilkulchai, Nathalie Bourg, Lydie Brenguier, Catherine Devaud, Patricia Pasturaud, Carinne Roudaut, Dominique Hillaire, Maria-Rita Passos-Bueno, Jay A. Tischfield |
| Natural killer cell receptors: the offs and ons of NK cell recognition.(natural killer) | Biological sciences | David H. Raulet, Werner Held |
| Natural resistance and nitric oxide. | Biological sciences | Carl Nathan |
| Neuroligin 1: a splice site-specific ligand for beta-neurexins. | Biological sciences | Thomas C. Sudhof, Markus Missler, Konstantin Ichtchenko, Yutaka Hata, Thai Nguyen, Beate Ullrich, Carolyn Moomaw |
| Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. | Biological sciences | Stephen M. Strittmatter, Mark C. Fishman, Christoph Fankhauser, Paul L. Huang, Hiroshi Mashimo |
| Neuronal target recognition. (Review) | Biological sciences | S. Lawrence Zipursky, Paul A. Garrity |
| New models in vogue for circadian clocks. | Biological sciences | Steve A. Kay, Andrew J. Millar |
| Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy. | Biological sciences | David S. Bredt, Jay E. Brenman, Daniel S. Chao, Houhui Xia, Ken Aldape |
| No end yet to messenger RNA 3' processing.(understanding the biochemical 3' processing reaction) | Biological sciences | Walter Keller |
| Nonclassical binding of formylated peptide in crystal structure of the MHC class Ib molecule H2-M3. | Biological sciences | Clive Slaughter, Johann Deisenhofer, Per A. Peterson, Chyung-Ru Wang, A. Raul Castano, Kirsten Fischer Lindahl |
| Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life? | Biological sciences | Pierre Chambon, Manuel Mark, Philippe Kastner |
| NSF-independent fusion mechanisms. (N-ethylmaleimide-sensitive factor) | Biological sciences | Katherine L. Wilson |
| Nuclear export signals and the fast track to the cytoplasm. | Biological sciences | Larry Gerace |
| Nucleocapsid and glycoprotein organization in an enveloped virus. | Biological sciences | Thomas J. Smith, Norman H. Olson, Timothy S. Baker, Michael G. Rossmann, R. Holland Cheng, Richard J. Kuhn, Hok-Kin Choi |
| OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. | Biological sciences | Patrick Matthias, Micel Strubin, John W. Newell |
| On base flipping.(Minireview) | Biological sciences | Richard J. Roberts |
| ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome. (origin recognition complex) | Biological sciences | Michael Weinrich, Bruce Stillman, Chun Liang |
| Overcoming a nucleosomal barrier to transcription. | Biological sciences | Gary Felsenfeld, Vasily M. Studitsky, David J. Clark |
| Overexcited or inactive ion channels in muscle disease. | Biological sciences | Reinhardt Rudel, Eric P. Hoffman, Frank Lehmann-Horn |
| Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformation.(receptor for hyaluronan-mediated motility) | Biological sciences | Rashmin C. Savani, Arnold H. Greenberg, Christine L. Hall, Baihua Yang, Xuiwei Yang, Shiwen Zhang, Maureen Turley, Shanti Samuel, Laurie A. Lange, Chao Wang, Genevieve D. Curpen, Eva A. Turley |
| Overexpression of the neural growth-associated protein GAR-43 induces nerve sprouting in the adult nervous system of transgenic mice. | Biological sciences | Silvia Arber, Ludwig Aigner, Josef P. Kapfhammer, Thorsten Laux, Corinna Schneider, Florence Botteri, Hans-Ruedi Brenner, Pico Caroni |
| p19(super Skp1) and p45(super Skp2) are essential elements of the cyclin A-CDK2 S phase kinase. | Biological sciences | David Beach, Hui Zhang, Ryuji Kobayashi, Konstantin Galakitionov |
| P25(super rum1) order S phase and mitosis by acting as an inhibitor of the p34(super cdc2) mitotic kinase. | Biological sciences | Paul M. Nurse, Jaime Correa-Bordes |
| p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches. | Biological sciences | Arnold Levine, Brian Elenbaas, Jack Griffith, Suman Lee |
| p65(super cdc18) plays a major role controlling the initiation of DNA replication in fission yeast. | Biological sciences | Paul M. Nurse, Hideo Nishitani |
| par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. | Biological sciences | Su Guo, Kenneth J. Kemphues |
| Phage T4 homologous strand exchange: a DNA helicase, not the strand transferase, drives polar branch migration. | Biological sciences | Frank Salinas, Thomas Kodadek |
| Phosphatidylinositol (3,4,5)P(sub 3) interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins.(Src homology 2, phosphoinositide) | Biological sciences | Lewis C. Cantley, Lucia E. Rameh, Ching-Shih Chen |
| Phospholipid signaling. | Biological sciences | Nullin Divecha, Robin F. Irvine |
| Phosphorylation of p34(super cdc2) regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. | Biological sciences | Heidi A. Lane, Erich A. Nigg, Anne Blangy, Pierre d'Herin, Maryannick Harper, Michel Kress |
| Phyllopod functions in the fate determination of a subset of photoreceptors in Drosophila. | Biological sciences | Gerald M. Rubin, Marc Therrien, Henry C. Chang, Noah M. Solomon, Felix D. Karim, Tanya Wolff, David A. Wassarman |
| Piece de resistance: novel classes of plant disease resistance genes. | Biological sciences | Jeffery L. Dangl |
| Polycystic kidney disease: the complete structure of the PKD1 gene and its protein.(The International Polycystic Kidney Disease Consortium) | Biological sciences | |
| pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos.(Caenorhabditis elegans) | Biological sciences | Rueyling Lin, Samantha Thompson, James R. Priess |
| Posttranslational protein transport in yeast reconstituted with a purified complex of sec proteins and Kar2p. | Biological sciences | Tom A. Rapoport, Enno Hartmann, Steffen Panzner, Lars Dreier, Susanne Kostka |
| Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein.(prion protein) | Biological sciences | Michael Scott, Stephen J. DeArmond, Ruth Gabizon, Fred E. Cohen, Marilyn Torchia, Glenn C. Telling, James Mastrianni, Stanely B. Prusiner |
| Prokaryotic and eukaryotic replicons. | Biological sciences | Joel A. Huberman |
| Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. | Biological sciences | Oliver Smithies, Scott G. Morham, H.S. Kim, Charles D. Loftin, Howard F. Tiano, Joel F. Mahler, Kimberley D. Kluckman, Christopher A. Lee, Robert Langebach, Burhan I. Ghanayem, Patricia C. Chulada, Eugenia H. Goulding |
| Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. | Biological sciences | Oliver Smithies, Scott G. Morham, J. Charles Jennette, Robert Langenbach, Charles D. Loftin, Howard F. Tiano, Nectarios Vouloumanos, Joel F. Mahler, Kimberley D. Kluckman, Aric Ledford, Christopher A. Lee |
| Protease activation during apoptosis: death by a thousand cuts? | Biological sciences | Douglas R. Green, Seamus J. Martin |
| Protein facilitation of group 1 intron splicing by assembly of the catalytic core and the 5'splice site domain. | Biological sciences | Thomas Cech, Kevin M. Weeks |
| Protein import into nuclei: Association and dissociation reactions involving transport substrate, transport factors, and nucleoporins. | Biological sciences | Gunter Blobel, Michael Rexach |
| Protein kinase A and hedgehog signaling in Drosophila limb development. | Biological sciences | Jin Jiang, Gary Struhl |
| Protein translocation across mitochondrial membranes: what a long, strange trip it is. | Biological sciences | Kathleen R. Ryan, Robert E. Jensen |
| PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus. | Biological sciences | Brian Seed, Tara Pouyani |
| Purification and properties of an ATP-dependent nucleosome remodeling factor. | Biological sciences | Carl Wu, Toshio Tsukiyama |
| Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme. | Biological sciences | Carol W. Greider, Kathleen Collins, Ryuji Kobayashi |
| Qualifying for the licence to replicate.(the absence of the minichromosome maintenance genes inhibits replication) | Biological sciences | Patrick H. O'Farrell, Tin Tin Su, Peter J. Follette |
| Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion. | Biological sciences | Marino Zerial, Harald Stenmark, Oliver Ullrich, Gaetano Vitale |
| Rac mediates growth factor-induced arachidonic acid release. | Biological sciences | Johannes L. Bos, Frank McCormick, Alan Hall, Maikel P. Peppelenbosch, Rong-Guo Qiu, Alida M.M. de Vries-Smits, Leon G.J. Tertoolen, Siegfried W. de Laat, Marc H. Symons |
| RbI2p, a yeast protein that binds to beta-tubulin and participates in microtubule function in vivo. | Biological sciences | Leticia R. Vega, Julie E. Archer, Frank Solomon |
| Reevaluation of the roles of protein S and gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3. | Biological sciences | Paul J. Godowski, Jian Chen, Melanie R. Mark, Michael D. Sadick, Helga Raab, Glenn R. Hammonds |
| Regulation of chromosomal replication in E. coli: sequestration and beyond.(Escherichia coli) | Biological sciences | Elliott Crooke |
| Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs. | Biological sciences | Frances M. Brodsky, Shu-Hui Liu, Mei Lie Wong, Charles S. Craik |
| Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors? | Biological sciences | Joseph Schlessinger, Irit Lax, Mark Lemmon |
| Replication arrest. | Biological sciences | Tania A. Baker |
| REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. | Biological sciences | Gail Mandel, Jayhong A. Chong, Jose Tapia-Ramirez, Sandra Kim, Juan J. Toledo-Aral, Yingcong Zheng, Michael C. Boutros, Yelena M. Altshuller, Michael A. Frohman, Susan D. Kraner |
| Retrovirus receptors. | Biological sciences | Robin A. Weiss, Chetankumar S. Tailor |
| Reversal of intrinsic DNA bends in the IFN-beta gene enhancer by transcription factors and the architectural protein HMG I(Y).(interferon-beta; high mobility group protein) | Biological sciences | Tom Maniatis, Dimitris Thanos, James V. Falvo |
| Rho family members: activators of MAP kinase cascades. | Biological sciences | Jonathan A. Cooper, Anne B. Vojtek |
| Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. | Biological sciences | Alan Hall, Catherine D. Nobes |
| Riding the polar winds: chromosomes motor down East. | Biological sciences | Margaret T. Fuller |
| RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. | Biological sciences | Philip Leder, Ben Z. Stanger, Brian Seed, Emily Kim, Tae-Ho Lee |
| RNA export. | Biological sciences | Iain W. Mattaj, Elisa Izaurralde |
| SARs are cis DNA elements of chromosome dynamics: synthesis of a SAR repressor protein.(scaffold-associated regions) | Biological sciences | Ulrich K. Laemmli, Reiner Strick |
| SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat.(spinocerebellar ataxia type 1) | Biological sciences | Harry T. Orr, Huda Y. Zoghbi, Eric N. Burright, H. Brent Clark, Antonio Servadio, Toni Matilla, Rodney M. Feddersen, Wael S. Yunis, Lisa A. Duvick |
| schnurri is required for Drosophila dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. | Biological sciences | Konrad Basler, Markus Affolter, Nicole C. Grieder, Denise Nellen, Richard Burke |
| SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. | Biological sciences | Mark T. Keating, Jeffrey A. Towbin, Arthur J. Moss, Zhizhong Li, Qing Wang, Jennifer L. Robinson, Igor Splawski, Jiaxiang Shen, Donald Atkinson |
| SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF. (adenosine triphosphate) | Biological sciences | Anastassios Economou, Joseph A. Pogliano, Jonathan Beckwith, Donald B. Oliver, William Wickner |
| Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells. | Biological sciences | Nathalie Rugani, Louis Sarda, Olivier Fourcade, Marie-Francoise Simon, Cecile Viode, Francois Leballe, Ashraf Ragab, Bernard Fournie, Hugues Chap |
| Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. | Biological sciences | Robb Krumlauf, Sydney Brenner, Mariann Bienz, Richard S. Mann, Heike Popperl, Michele Studer, Sui-Kwong Chan, Sam Aparicio |
| Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. | Biological sciences | Anning Lin, Audrey Minden, Francois-Xavier Claret, Arie Abo, Micheal Karin |
| Selective protein degradation: a journey's end within the proteasome. | Biological sciences | Stefan Jentsch, Stephan Schlenkar |
| Semaphorin II can function as a selective inhibitor of specific synaptic arborizations. | Biological sciences | Corey S. Goodman, Alex L. Kolodkin, Helen Sink, David J. Matthes |
| Sense from nonsense: RNA editing in mitochondria of kinetoplastid protozoa and slime molds. | Biological sciences | Larry Simpson, Otavio H. Thiemann |
| Serpentine cAMP receptors may act through a G protein-independent pathway to induce postaggregative development in dictyostelium. | Biological sciences | Richard A. Firtel, Gavin R. Schnitzler, Celia Briscoe, Jason M. Brown |
| Sex in the '90s. | Biological sciences | Amanda Swain, Lisa C. Ryner |
| Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. | Biological sciences | Edward J. Louis, Ian D. Hickson, Paul M. Watt, Rhona H. Borts |
| Shedding light on the chloroplast protein import machinery. | Biological sciences | Danny J. Schnell |
| Signals for death and survival: a two-step mechanism for cavitation in the vertebrate embryo. | Biological sciences | Gail R. Martin, Electra Coucouvanis |
| Signal transduction and membrane traffic: the PITP/phosphoinositide connection. (phosphatidylinositol transfer protein) | Biological sciences | Lewis C. Cantley, Mordechai Liscovitch |
| Small peptides activate the latent sequence-specific DNA binding function of p53. | Biological sciences | David P. Lane, Ted R. Hupp, Alison Sparks |
| Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein. | Biological sciences | Danny Reinberg, Edio Maldonado, Mitsuhiko Ikura, Stefan Bagby, Sungjoon Kim, Kit I. Tong |
| Somatic hypermutation: how many mechanisms diversify V region sequences?(variable) | Biological sciences | Nancy Maizels |
| Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. | Biological sciences | T.M. Jessell, J. Ericson, J. Muhr, M. Placzek, T. Lints, T. Edlund |
| Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. | Biological sciences | Shigetada Nakanishi, Ryuichi Shigemoto, Motoya Katsuki, Yutaka Fukuda, Kenji Nakamura, Kazuki Nakao, Masayuki Masu, Hideki Iwakabe, Yoshiaki Tagawa, Tomomitsu Miyoshi, Masayuki Yamashita, Hitoshi Sasaki, Kano Hiroi, Yashisa Nakamura, Masahiko Takada |
| Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. | Biological sciences | C.J. Marshall |
| Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. | Biological sciences | Harvey F. Lodish, Benjamin G. Neel, Lewis C. Cantley, Ursula Klingmuller, Ulrike Lorenz |
| Spindle orientation and asymmetric cell fate. | Biological sciences | Jurgen A. Knoblich, Michelle S. Rhyu |
| SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation. | Biological sciences | Peter Walter, Stephan C. Ogg |
| Stem cell patterning and fate in human epidermis. | Biological sciences | Fiona M. Watt, Philip H. Jones, Steven Harper |
| Steroid hormone receptors: many actors in search of a plot.(mechanism of steroid hormone action) | Biological sciences | Peter Herrlich, Gunther Schutz, Miguel Beato |
| Strong voltage-dependent inward rectification of inward rectifier K+ channels is caused by intracellular spermine. | Biological sciences | B. Fakler, U. Brandle, E. Glowatzki, S. Weidemann, H.-P. Zenner, J.P. Ruppersberg |
| Structure and function of the beta-2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif.(cell adhesion molecule) | Biological sciences | L.L. Isom, D.S. Ragsdale, K.S. De Jongh, R.E. Westenbroek, B.F.X. Reber, T. Scheuer, W.A. Catterall |
| Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration. | Biological sciences | Phoebe Rice, Kiyoshi Mizuuchi |
| Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold. | Biological sciences | Thomas C. Sudhof, Stephen R. Sprang, R. Bryan Sutton, Bazbek A. Davletov, Albert M. Berghuis |
| Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain. | Biological sciences | Joseph Schlessinger, Paul B. Sigler, Mark A. Lemmon, Kathryn M. Ferguson |
| Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing. (Wilms' tumor) | Biological sciences | Nicholas D. Hastie, Veronica van Heyningen, Stefan H. Larsson, Jean-Paul Charlieu, Kiyoshi Miyagawa, Dieter Engelkamp, Minoo Rassoulzadegan, Allyson Ross, Francois Cuzin |
| Suppression of intestinal neoplasia by DNA hypomethylation. | Biological sciences | En Li, Robert A. Weinberg, Rudolf Jaenisch, Amin Fazeli, Peter W. Laird, Laurie Jackson-Grusby, Stephanie L. Dickinson, W. Edward Jung |
| Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. | Biological sciences | Fiona M. Watt, Joseph M. Carroll, M. Rosario Romero |
| Surprises at the 3' end of prokaryotic RNA.(minireview) | Biological sciences | Stanley N. Cohen |
| Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes. | Biological sciences | Louis H. Miller, David J. Roberts, Chetan E. Chitnis, David S. Peterson, Joseph D. Smith, Alister G. Craig, Diana E. Hudson-Taylor, Robert Pinches, Chris I. Newbold |
| Synaptic structure and function: dynamic organization yields architectural precision. (Review) | Biological sciences | Marie E. Burns, George J. Augustine |
| T7 RNA polymerase bypass of large gaps on the template strand reveals a critical role of the nontemplate strand in elongation. | Biological sciences | Paul W. Doetsch, Wei Zhou, Daniel Reines |
| TAFs and TFIIA mediate differential utilization of the tandem Adh promoters. | Biological sciences | Robert Tjian, Stig K. Hansen |
| Talking through walls: signaling in plant development. | Biological sciences | Jeffery L. Dangl, Julian I. Schroeder, Daphne Preuss |
| Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. | Biological sciences | Jamey D. Marth, Michael R. Hayden, Jamal Nasir, Stan B. Floresco, John R. O'Kusky, Virginia M. Diewert, Joy M. Richman, Jutta Zeisler, Anita Borowski, Anthony G. Phillips |
| Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. | Biological sciences | Shizuo Akira, Takashi Tanaka, Yoshihiro Yoneda, Nobuaki Yoshida, Sachiko Suematsu, Kanji Yoshida, Masanori Umemoto, Naoki Shirafuji, Hiroshi Fujiwara, Tadamitsu Kishimoto |
| Targeted disruption of the p50 subunit of Nf-kappa-B leads to multifocal defects in immune responses. | Biological sciences | David Baltimore, Hsiou-Chi Liou, William C. Sha, Elaine l. Tuomanen |
| TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. | Biological sciences | Thomas D. Petes, Stephanie E. Porter, Patricia W. Greenwell, Shara L. Kronmal, Johann Grassenhuber, Brigitte Obermaier |
| TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. | Biological sciences | Yosef Shiloh, Danilo A. Tagle, Francis Collins, Philip Hieter, Dwight M. Morrow |
| The 3' enhancer region determines the B/T specificity and pro-B/pre-B specificity of immunoglobulin V(sub kappa)-J(sub kappa) joining. | Biological sciences | Ken-ichi Yamamura, Hitoshi Sakano, Ryuji Hiramatsu, Richard R. Hardy, Kiwamu Akagi, Masao Matsuoka, Kunihiko Sakumi, Hiro Nakamura, Linda Kingsbury, Chella David |
| The ABC of channel regulation.(ATP-binding cassette superfamily) | Biological sciences | Christopher F. Higgins |
| The adipocyte: storage depot or node on the energy information superhighway? | Biological sciences | Jeffrey S. Flier |
| The anatomy of a bifunctional enzyme: structural basis for reduction of oxygen to water and synthesis of nitric oxide by cytochrome cd1. | Biological sciences | Stuart J. Ferguson, Janos Hajdu, Vilmos Fulop, James W.B. Moir |
| The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases. | Biological sciences | John Fisher, George D. Yancopoulos, Greg Lemke, Martin Gore, Claudio Basilico, Piotr Masiakowski, Czeslaw Radziejewski, Peter S. DiStefano, Trevor N. Stitt, David J. Glass, Greg Conn, Cary Lai, Joanne Bruno, Karen Mattsson, David R. Gies, Pamela F. Jones, Terence E. Ryan, Nancy J. Tobkes, D.H. Chen, George L. Long, Mitchell P. Goldfarb |
| The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons. | Biological sciences | Marc Tessier-Lavigne, Sophia A. Colamarino |
| The bacterial flagellum: from genetic network to complex architecture. | Biological sciences | Lucy Shapiro |
| The BELL1 gene encodes a homeodomain protein involved in pattern formation in the Arabidopsis ovule primordium. | Biological sciences | Robert L. Fischer, Zora Modrusan, Nir Ohad, Leonore Reiser, Linda Margossian, Alon Samach, George W. Haughn |
| The Bloom's syndrome gene product is homologous to RecQ helicases. | Biological sciences | Joanna Groden, Nathan A. Ellis, Tian-Zhang Ye, Joel Straughen, David J. Lennon, Susan Ciocci, Maria Proytcheva, James German |
| The body language of cells: the intimate connection between cell adhesion and behavior. | Biological sciences | Michael W. Klymkowsky, Brian Parr |
| The bond between sisters. (Minireview) | Biological sciences | Jeff J. Sekelsky, R. Scott Hawley |
| The carbonic anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin. | Biological sciences | Joseph Schlessinger, Takeshi Sakurai, Douglas O. Clary, Ricardo Martinez, Gilad Barnea, Martin Grumet, Sima Lev, Elior Peles, Moshe Nativ, Philip L. Campbell, Gregory D Plowman, James Schilling |
| The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously.(Caenorhabditis) | Biological sciences | H. Robert Horvitz, Michael A. Herman, Robert K. Herman, Jocelyn E. Shaw, Larissa L. Vassilieva |
| The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-medicated signal transduction.(Caenorhabditis elegans, kinase suppressor of RAS) | Biological sciences | Min Han, Meera Sundaram |
| The cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. | Biological sciences | Alan R. Lehmann, Errol C. Friedberg, Randy Legerski, Lei Li, Roger A. Schultz, Karla A. Henning, Narayan Iyer, Lisa D. McDaniel, Michael S. Reagan, Miria Stefanini, Lynne V. Mayne |
| The CONSTANS gene of Arabidopsis promotes flowering and encodes a protein showing similarities to zinc finger transcription factors. | Biological sciences | Rudiger Simon, Frances Robson, George Coupland, Joanna Putterill, Karen Lee |
| The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage. | Biological sciences | Aaron Klug, John T. Finch, William G. Scott |
| The crystal structure of haeIII methyltransferase covalently complexed to DNA: an extrahelical cytosine and rearranged base pairing. | Biological sciences | Gregory L. Verdine, Karin M. Reinisch, Lin Chen, William Nunn Lipscomb |
| The CTL's kiss of death.(cytolytic T lymphocytes) | Biological sciences | Gideon Berke |
| The Drosophila schnurri gene acts in the Dpp/TGFbeta signaling pathway and encodes a transcription factor homologous to the human MBP family. | Biological sciences | Michael B. O'Connor, Rahul Warrior, Sandra G. Kazuko, Anthea Letsou, Kavita Arora, Heng Dai, Joumana Jamal |
| The elemental principles of calcium signaling. | Biological sciences | Michael J. Berridge, Martin D. Bootman |
| The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. | Biological sciences | Elliott Kieff, George Mosialos, Mark Birkenbach, Ramana Yalamanchili, Todd VanArsdale, Carl Ware |
| The FIP1 gene encodes a component of the yeast pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase. | Biological sciences | Joachim Lingner, Walter Keller, Pascal J. Preker, Lionel Minvielle-Sebastia |
| The formation of Golgi stacks from vesiculated Golgi membranes requires two distinct fusion events. | Biological sciences | Jan-Michael Peters, Vivek Malhotra, Richard Jacobs, Nicki Watson, Usha Acharya, Marilyn G. Farquhar |
| The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction. | Biological sciences | Yosef Yarden, Janna M. Blechman, Sima Lev, Jacob Barg, Miriam Eisenstein, Baruch Vaks, Zvi Vogel, David Givol |
| The genetic basis for specific anosmia to isovaleric acid in the mouse. | Biological sciences | Randall R. Reed, Irene C. Griff |
| The global folding of four-way helical junction in RNA, including that in U1 snRNA. | Biological sciences | David M.J. Lilley, Alastair I.H. Murchie, Derek R. Duckett |
| The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. | Biological sciences | Iain W. Mattaj, Reinhard Luhrmann, Wilbert C. Boelens, Utz Fischer, Jochen Huber |
| The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development.(fibroblast growth factor) | Biological sciences | Marc W. Kirschner, Noriyuki Kinoshita, Jeremy Minshull |
| The intracellular localization of messenger RNAs. | Biological sciences | Daniel St. Johnston |
| The ksr-1 gene encodes a novel protein kinase involved in ras-mediated signaling in C. elegans.(kinase suppressor of RAS, Caenorhabditis elegans) | Biological sciences | H. Robert Horvitz, Kerry Kornfeld, Dennis B. Hom |
| The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes. | Biological sciences | Thomas E. Wellems, Xin-zhuan Su, Virginia M. Heatwole, Samuel P. Wertheimer, Francoise Guinet, Jacqueline A. Herrfeldt, David S. Peterson, Jeffrey A. Ravetch |
| The long and short of hedgehog signaling. (hedgehog genes as intercellular signals) | Biological sciences | Randy L. Johnson, Cliff Tabin |
| The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene.(Drosophila melanogaster) | Biological sciences | Jeff J. Sekelsky, R. Scott Hawley, Kumar L. Hari, Kim S. McKim, James B. Boyd, Anne Santerre |
| The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system. | Biological sciences | Matthias F. Bauer, Walter Neupert, Michael Brunner, Jutta Berthold, Hans-Christoph Schneider, Christian Klaus, Klaus Dietmeier |
| The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing.(origin recognition complex 1 protein) | Biological sciences | Bruce Stillman, Stephen P. Bell, Ryuji Kobayashi, Jay Mitchell, Jess Leber |
| The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. | Biological sciences | Nobutaka Hirokawa, Yoko Sekine-Aizawa, Yasuski Okada, Hiroto Yamazaki |
| The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. | Biological sciences | Bruce Stillman, Paul D. Kaufman, Ryuji Kobayashi, Naama Kessler |
| The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex. | Biological sciences | Gunter Blobel, Aurelian Radu, Mary Shannon Moore |
| The price of repression. (eukaryotic gene expression) | Biological sciences | Alexander D. Johnson |
| The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer. | Biological sciences | Josef Brunner, Bernhard Dobberstein, Bruno Martoglio, Michael W. Hofmann |
| The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. | Biological sciences | Philip N. Tsichlis, Andrius Kazlauskas, Deborah K. Morrison, David R. Kaplan, Thomas F. Franke, Sung-II Yang, Tung O. Chan, Ketaki Datta |
| The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. | Biological sciences | Caroline S. Hill, Judy Wynne, Richard Treisman |
| The role of N-glycans in the secretory pathway. | Biological sciences | Klaus Fiedler, Kai Simons |
| The RXR heterodimers and orphan receptors.(retinoid X receptor) | Biological sciences | Ronald M. Evans, David J. Mangelsdorf |
| The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of Apc-Min-induced intestinal neoplasia. | Biological sciences | Melina MacPhee, Kenneth P. Chepenik, Rebecca A. Liddell, Kelly K. Nelson, Linda D. Siracusa, Arthur M. Buchberg |
| The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development. | Biological sciences | Benjamin G. Neel, Sergei Y. Sokol, Terry L. Tang, Robert M. Freeman Jr., Alana M. O'Reilly |
| The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. | Biological sciences | J. Silvio Gutkind, Mario Chiariello, Toru Miki, Omar A. Coso, Jin-Chen Yu, Hidemi Teramoto, Piero Crespo, Ningzhi Xu |
| The solution structure of the human ETS1-DNA complex reveals a novel mode of binding and true side chain intercalation. | Biological sciences | Joseph Shiloach, Robert J. Fisher, G. Marius Clore, Angela M. Gronenborn, Milton H. Werner, Constance L. Fisher, Loc Trinh |
| The S. pombe cdc15 gene is a key element in the reorganization of F-actin at mitosis. | Biological sciences | Christian Fankhauser, Viesturs Simanis, Alexandre Reymond, Lorenzo Cerutti, Suzan Utzig, Kay Hoffmann |
| The stabilization of repetitive tracts of DNA by variant repeats requires a functional DNA mismatch repair system. | Biological sciences | Thomas D. Petes, Shaun M. Heale |
| The structure of a Ca2+ -binding epidermal growth factor-like domain: its role in protein-protein interactions. | Biological sciences | George G. Brownlee, David Stuart, Zihe Rao, Penny Handford, Mark Mayhew, Vroni Knott |
| The structure of the G protein Heterotrimer G(sub i-alpha)-beta(sub 1)-gamma (sub 2). | Biological sciences | Ethan Lee, Alfred G. Gilman, Stephen R. Sprang, David E. Coleman, Mark A. Wall, Jorge A. Ingiguez-Lluhi, Bruce A. Posner |
| The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.(tumor necrosis factor receptor, TNFR-associated factor) | Biological sciences | Mike Rothe, David V. Goeddel, Ming-Gui Pan, William J. Henzel, T. Merrill Ayres |
| The TNF receptor 1-associated protein TRADD signals cell death and NF-kappaB activation. (tumor necrosis factor; TNFR1-associated death domain protein) | Biological sciences | Hailing Hsu, David V. Goeddel, Jessie Xiong |
| The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response.(Pto-interacting 1) | Biological sciences | Gregory B. Martin, Ray A. Bressan, Jianmin Zhou, Ying-Tsu Loh |
| The topology of the kinetoplast DNA network. | Biological sciences | Nicholas R. Cozzarelli, Paul T. Englund, Junghuei Chen, Carol A. Rauch, James H. White |
| The torso receptor tyrosine kinase can activate raf in a ras-independent pathway. | Biological sciences | Norbert Perrimon, Tze-Bin Chou, Xianyu Steven Hou, Michael B. Melnick |
| The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. | Biological sciences | George Kollias, Matthias Grell, Werner Lesslauer, Eleni Douni, Harald Wajant, Matthias Lohden, Matthias Clauss, Beate Maxeiner, Spiros Georgopoulos, Klaus Pfizenmaier, Peter Scheurich |
| The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. (variable, diversity and joining gene segments) | Biological sciences | Yijie Gao, Frederick W. Alt, Brian Seed, Thomas D. Stamato, Guillermo E. Taccioli, Zhiying Li, Tomas Otevrel, Hwei-Ling Cheng |
| Three-dimensional structure of E. coli core RNA polymerase: promoter binding and elongation conformations of the enzyme.(Escherichia coli) | Biological sciences | Seth A. Darst, Andrey Polyakov, Elena Severinova |
| Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and Ick cooperate in hematopoietic cell proliferation. | Biological sciences | Tadatsugu Taniguchi, Yasuhiro Minami, Roger M. Perlmutter, Yoshihide Tsujimoto, Tadaaki Miyazaki, Zhao-Jun Liu, Atsuo Kawahara, Kyoko Yamada, Edward L. Barsoumian |
| Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage. | Biological sciences | Kevin P. Campbell |
| Thrombin receptor ligation and activation Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. | Biological sciences | Christopher L. Carpenter, Alex Toker, Thomas P. Stossel, John H. Hartwig, Paul A. Janmey, Gary M. Bokoch, Lance A. Taylor |
| TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin. | Biological sciences | Gerald R. Crabtree, Stuart L. Schreiber, Xiao-Feng Zheng, David Fiorentino, Jie Chen |
| Toward a molecular understanding of skeletal development. | Biological sciences | Rik Derynck, Adrian Erlebacher, Ellen H. Filvaroff, Stephen E. Gitelman |
| Transcriptional regulation by extracellular signals: mechanisms and specificity. | Biological sciences | Caroline S. Hill, Richard Treisman |
| Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. (megakaryocyte growth and development factor) | Biological sciences | Stuart H. Orkin, Ramesh A. Shivdasani, Margery F. Rosenblatt, Dorothea Zucker-Franklin, Carl W. Jackson, Pamela Hunt, Chris J.M. Saris |
| Transfer RNA: from minihelix to genetic code. | Biological sciences | Paul Schimmel, Lluis Ribas De Pouplana |
| Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis. | Biological sciences | Anne Ryan, Andrew Grupe, Timothy A. Stewart, Bruce Hultgren, Yan Hui Ma, Michele Bauer |
| Translational regulation in development. | Biological sciences | Phillip D. Zamore, Ruth Lehmann, Daniel Curtis |
| Translational regulation of oskar mRNA by bruno, an ovarian RNA-binding protein, is essential. | Biological sciences | Karen Kerr, Paul M. Macdonald, Jeongsil Kim-Ha |
| Trinucleotide repeats that expand in human disease form hairpin structures in vitro. | Biological sciences | Cynthia T. McMurray, A. Marquis Gacy, Geoffrey Goellner, Nenad Juranic, Slobodan Macura |
| Trypanosome invasion of mammalian cells requires activation of the TGFbeta signalling pathway. | Biological sciences | Mark E. Ewen, Mao Ming, Miercio E.A. Pereira |
| Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. | Biological sciences | John C. Reed, Toshiyuki Miyashita |
| Ubiquitin is attached to membranes of baculovirus particles by a novel type of phospholipid anchor. | Biological sciences | Gayle Smith, Linda A. Guarino, Wen Dong |
| Unique response pathways are established by allosteric interactions among nuclear hormone receptors. | Biological sciences | Ronald M. Evans, Kazuhiko Umesono, Barry Marc Forman, Jasmine Chen |
| Unraveling chemosensory diversity. | Biological sciences | Linda B. Buck |
| Vaccinia virus encodes a soluble Type 1 interferon receptor of novel structure and broad species specificity. | Biological sciences | Geoffrey L. Smith, Julian A. Symons, Antonio Alcami |
| Vacuolar biogenesis in yeast: sorting out the sorting proteins. | Biological sciences | Elizabeth Conibear, Tom H. Stevens |
| Vertebrate left-right development.(biological asymmetries) | Biological sciences | H. Joseph Yost |
| Vesicle biogenesis: the coat connection. | Biological sciences | Vivek Malhotra, Arrate Mallabiabarrena |
| Viral latency in HIV disease.(human immunodeficiency syndrome) | Biological sciences | Joseph M. McCune |
| Viral RNA as a potential target for two independent mechanisms of replicase-mediated resistance against cucumber mosaic virus. | Biological sciences | Peter Palukaitis, Karl-Heinz Hellwald |
| Visualization of chromosomal domains with boundary element-associated factor BEAF-32.(boundary element-associated factor) | Biological sciences | Keji Zhao, Craig M. Hart, Ulrich K. Laemmli |
| What the fly's glia tell the fly's brain.(glial cell functions in Drosophila) | Biological sciences | Barbara A. Barres, Frank W. Pfrieger |
| Why is DsbA such an oxidizing disulfide catalyst? | Biological sciences | Philipp Korber, Ulla Grauschopf, Jakob R. Winther, Thomas Zander, Petra Dallinger, James C.A. Bardwell |
| Xenopus chordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation. | Biological sciences | Ethan Bier, Vincent Francois |
| XKlp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. | Biological sciences | Eric Karsenti, Isabelle Vernos, Janet Heasman, Chris Wylie, Tatsuya Hirano, Jos Raats |
| xol-1 acts as an early switch in the C. elegans male hermaphrodite decision. | Biological sciences | Barbara J. Meyer, Leilani M. Miller, Nicholas R. Rhind, Jennifer B. Kopczynski |
| X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. | Biological sciences | John A. Thomson, James P. Griffith, Joseph L. Kim, Eunice E. Kim, Michael D. Sintchak, Matthew J. Fitzgibbon, Mark A. Fleming, Paul R. Caron, Kathy Hsiao, Manuel A. Navia |
| Yama/CPP32beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. | Biological sciences | Guy S. Salvesen, Karen O'Rourke, Vishva M. Dixit, Muneesh Tewari, Long T. Quan, Serge Desnoyers, Zhi Zeng, David R. Beidler, Guy G. Poirier |
| Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway.(mitogen-activated protein kinase) | Biological sciences | Gerald M. Rubin, Ilaria Rebay |
| Yes, but do they still get headaches?(effects of nonsteroidal anti-inflammatory drugs) | Biological sciences | William L. Smith, David DeWitt |
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