Nature Medicine 2001 - Abstracts

Nature Medicine 2001
TitleSubjectAuthors
11-color, 13-parameter flow cytometry: identification of human naive T cells by phenotype, function, and T-cell receptor diversity.HealthStephen C. De Rosa, Leonard A. Herzenberg, Mario Roederer
A battle cry for biomedicine.(anti-bioterrorism research)(Editorial)Health 
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.HealthPeter Carmeliet, Mieke Dewerchin, Desire Collen, Dieter Nuyens, Milan Stengl, Saran Dugarmaa, Tom Rossenbacker, Veerle Compernolle, Yoram Rudy, Jos F. Smits, Willem Flameng, Colleen E. Clancy, Lieve Moons, Marc A. Vos, Klaus Benndorf, Edward Carmeliet
Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of G(alpha)sub(q)/ G(alpha)sub(11) in cardiomyocytes.(Statistical Data Included)HealthKenneth R. Chien, Nina Wettschureck, Hartmut Ruten, Alexandra Zywietz, Doris Gehring, Tom M. Wilkie, Ju Chen, Stefan Offermanns
A cannabinoid mechanism in relapse to cocaine seeking.(Statistical Data Included)HealthYavin Shaham, Taco J. de Vries, Judith R. Homberg, Hans Crombag, Karianne Schuurman, Jeanine Dieben, Louk J. M. J. Vanderschuren, Anton N. M. Schoffelmeer
Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc (super)delta716 knockout mice.HealthMasahiro Sonoshita, Kazuaki Takaku, Nobuya Sasaki, Yukihiko Sugimoto, Fumitaka Ushikubi, Shuh Narumiya, Masanobu Oshima, Makoto M. Taketo
Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype.(Statistical Data Included)HealthNan Wang, Shravan K. Chintala, M. Elizabeth Fini, Joel S. Schuman
Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune type 1 diabetes.HealthOlga V. Naidenko, Mitchell Kronenberg, Yasuhiko Koezuka, Shayan Sharif, Guillermo A. Arreaza, Peter Zucker, Qing-Sheng Mi, Terry L. Delovitch, Jean-Marc Gombert, Maria Leite-de-Moraez, Christine Gouarin, Ren Zhu, Agathe Hameg, Toshinori Nakayama, Masaru Taniguchi, Francoise Lepault, Agnes Lehuen, Jean-Francois Bach, Andre Herbelin
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.(Statistical Data Included)HealthBruce M. Spiegelman, Nahum Sonenberg, Anne-Claude Gingras, Kyoko Tsukiyama-Kohara, Francis Poulin, Michinori Kohara, Christine T. DeMaria, Alan Cheng, Zhidan Wu, Asao Katsume, Mounib Elchebly, Mary-Ellen Harper, Michel L. Tremblay
A dominant-negative therapy for anthrax.HealthStephen H. Leppla
Adoptive transfer of minor histocompatibility antigen-specific T lymphocytes eradicates leukemia cells without causing graft-versus-host disease.(Statistical Data Included)HealthPierre Fontaine, Guillaume Roy-Proulx, Laurent Knafo, Chantal Baron, Denis-Claude Roy, Claude Perreault
Adoptive tumor therapy with T lymphocytes enriched through an IFN-gamma capture assay.(interferon)(Statistical Data Included)HealthMario Assenmacher, Heike Pohla, Christian Becker, Bernhard Frankenberger, Dolores Schendel J., Thomas Blankenstein, Thomas Schuler
Adult mice deficient in actinin-associated LIM-domain protein reveal a developmental pathway for right ventricular cardiomyopathy.(Statistical Data Included)HealthKenneth R. Chien, John Ross Jr., Mohammad Pashmforoush, Pascal Pomies, Kirk L. Peterson, Steve Kubalak, Andreas Hefti, Ueli Aebi, Mary C. Beckerle
Advances in schizophrenia.(Statistical Data Included)HealthGunvant K. Thaker, William T. Carpenter Jr.
A fresh facet for ouabain action.HealthGeorgios Scheiner-Bobis, Wilhelm Schoner
A link between diabetes and atherosclerosis: glucose regulates expression of CD36 at the level of translation.(Statistical Data Included)HealthErik Griffin, Alessandro Re, Nance Hamel, Chenzong Fu, Harry Bush, Timothy McCaffrey, Adam S. Asch
alpha-Synuclein and cytosolic dopamine: stabilizing a bad situation.HealthDavid Sulzer
AML1-ETO downregulates the granulocytic differentiation factor C/EBP(alpha) in t(8;21) myeloid leukemia.(Statistical Data Included)HealthThomas Pabst, Beatrice U. Mueller, Nari Harakawa, Claudia Schoch, Torsten Haferlach, Gerhard Behre, Wolfgang Hiddemann, Dong-Er Zhang, Daniel G. Tenen
A mouse model for hepatitis C virus infection?.HealthNelson Fausto
Amyloid beta vaccination: reduced plaques and improved cognition.HealthSteven G. Younkin
A new entry route for HIV.(human immunodeficiency virus)HealthBryan R. Cullen
A new feature on the cholesterol-lowering landscape.HealthDaniel J. Rader
A new latent HIV reservoir.HealthRichard A. Koup
A newly discovered human pneumovirus isolated from young children with respiratory tract disease.(Statistical Data Included)HealthBernadette G. van den Hoogen, Lan C. de Jong, Jan Groen, Ronald de Groot, Ron A. M. Fouchier, Albert D. M. E. Osterhaus
Annan gives prise miney to AIDS Fund.HealthJohn Schuster
Annexin-V imaging for noninvasive detection of cardiac allograft rejection.HealthAllan Green, Jagat Narula, Elmo R. Acio, Navneet Narula, Louis E. Samuels, Billy Fyfe, Diana Wood, Jane M. Fitzpatrick, P. N. Raghunath, John E. Tomaszewski, Christine Kelly, Neil Steinmetz, Diwakar Jain, H. William Strauss, Francis G. Blankenberg, Jeffrey Leppo, John F. Tait
Annihilating host defense.HealthMichael M. Frank
A novel erythroid-specific marker of transmissible spongiform encephalopathies.(Statistical Data Included)HealthGino Miele, Jean Manson, Michael Clinton
A novel influenza A virus mitochondrial protein that induces cell death.HealthUlrich Schubert, James Gibbs, Jonathan W. Yewdell, Jack R. Bennink, Weisan Chen, Paul A. Calvo, Daniela Malide, Igor Bacik, Sameh Basta, Robert O'Neill, Jeanne Schickli, Peter Palese, Peter Henklein
A novel non-invasive, in vivo technique for the quantification of leukocyte rolling and extravasation at the sites of inflammation in human patients.(Statistical Data Included)HealthJuha Kirveskari, Minna H. Vesaluoma, Jukka A.O. Moilanen, Timo M.T. Tervo, Matthew W. Petroll, Linnolahti Eeva, Renkonen Risto
Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway.(Statistical Data Included)HealthKanchan Chitaley, Christopher J. Wingard, R. Clinton Webb, Heather Branam, Vivienne S. Stopper, Ronald W. Lewis, Thomas M. Mills
Anti-DNA meets NMDA in neuropsychiatric lupus.(N-methyl-D-aspartate)HealthBrian L. Kotzin, Elizabeth Kozora
Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.HealthDrazen B. Zimonjic, Yuji Takebayashi, Philippe Pourquier, Kentaro Nakayama, Steffen Emmert, Takahiro Ueda, Shin-Ichi Akiyama, Nicholas Popescu, Kenneth H. Kraemer, Yves Pommer
Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency.(Statistical Data Included)HealthXiao Xiao, Alan R. Tall, Xian-Cheng Jiang, Shucun Qin, Chunping Qiao, Koichi Kawano, Min Lin, Anna Skold
Apoptosis subversion: HIV-Nef provides both armor and sword.HealthJean Claude Ameisen
A post-genomic perspective.(genome sequencing)HealthDouglas B. Young
Apototic cells overexpress vinculin and induce vinculin-specific cytotoxic T-cell cross-priming.(Statistical Data Included)HealthOlfert Landt, Giovanna Cutrona, Massimo Ulivi, Manlio Ferrarini, Antonella Propato, Vittorio Francavilla, Enrico Schiafella, Rod Dunbar, Vincenzo Cerundolo, Vincenzo Barnaba
A protective player in the vascular response to injury.HealthStephen M. Schwartz
A quantitative assay for HIV DNA integration in vivo.(Statistical Data Included)HealthScott L. Butler, Mark S.T. Hansen, Frederic D. Bushman
A renaissance for the tumor immunosurveillance hypothesis.HealthLewis L. Lanier
A role for complement in transmissible spongiform encephalopathies.HealthFranco Cardone, Maurizio Pocchiari
A role for fibronectin in self-repair after ischemic injury.HealthDeane F. Mosher
A SADS defect in tumor cells provides optimism.(small accelerator for death signaling)HealthHiroshi Takahashi
A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus.(Statistical Data Included)HealthBetty Diamond, Lorraine A. DeGiorgio, N. Konstantin Konstantinov, Sunhee C. Lee, John A. Hardin, Bruce T. Volpe
Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies.(Statistical Data Included)HealthAngela Vincent, Werner Hoch, John McConville, Sigrun Helms, John Newsom-Davis, Arthur Melms
Autoimmune disease: why and where it occurs.HealthBrian L. Kotzin, Philippa Marrack, John Kappler
Biologist becomes first woman to lead Princeton.HealthStephen Horwitz
Biopanning and rapid analysis of selective interactive ligands.(Statistical Data Included)HealthRicardo J. Giordano, Marina Cardo-Vila, Johanna Lahdenranta, Renata Pasqualini, Wadih Arap
Bioterrorism: a clear and present danger.HealthH. Clifford Lane, Anthony S. Fauci, John La Montagne
Blood simple prion diagnostics.HealthAdriano Aguzzi
Breast cancer genetics: what we know and what we need.HealthBarbara L. Weber, Katherine N. Nathanson, Richard Wooster
Breast cancer genetics: what we know and what we need.(Statistical Data Included)HealthBarbara L. Weber, Richard Wooster, Katerine N. Nathanson
Canada tops cancer research impact list.HealthSimon Frantz
Canadian doctors unhappy at prescribing 'medicine'.HealthDavid Dickson
Cannabinoid activity curtails cocain craving.HealthDaniele Piomelli
Can stem cells cross lineage boundaries?HealthDavid J. Anderson, Fred H. Gage, Irving L. Weissman
Can the thymus win the battle against drug-resistants HIV?HealthBarton F. Haynes, Gregory D. Sempowski
CD4 (super)+ T-cell-epitope mutant virus selected "in vivo".(Statistical Data Included)HealthRolf M. Zinkernagel, Adrian Ciurea, Lukas Hunziker, Marianne M.A. Martinic, Annette Oxenius, Hans Hengartner
CD4 (super)+ T cells: the great escape.HealthRodney E. Phillips, Gillian D. Harcourt, David A. Price
Cell identification and isolation on the basis of cytokine secretion: a novel tool for investigating immune responses.(Statistical Data Included)HealthVictor Turcanu, Neil A. Williams
Cellular function of the Fanconi anemia pathway.HealthRobert C. Cumming, Manuel Buchwald, Alan D. D'Andrea
Changing the dosing schedule minimizes the disruptive effects of interferon on clock function.(circadian rhythms)(Statistical Data Included)HealthShigehiro Ohdo, Satoru Koyanagi, Hinako Suyama, Shun Higuchi, Hironori Aramaki
Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks.(Statistical Data Included)HealthCarsten Peterson, Javed Khan, Jun S. Wei, Marcus Ringner, Lao H. Saal, Marc Ladanyi, Frank Westermann, Frank Berthold, Manfred Schwab, Cristina R. Antonescu, Paul S. Meltzer
Clearing the way to mechanisms of autoimmunity.HealthAntony Rosen, Livia Casciola-Rosen
Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia.HealthByung Hee Han, Ronald B. DeMattos, Laura L. Dugan, Jeong Sook Kim-Han, Robert P. Brendza, John D. Fryer, Malca Kierson, John Cirrito, Kevin Quick, Judith A. K. Harmony, Bruce J. Aaronow, David M. Holtzman
c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations.HealthCelina M. D'Cruz, Edward J. Gunther, Robert B. Boxer, Jennifer L. hartman, Louis Sintasath, Susan E. Moody, James D. Cox, Seung I. Ha, George K. Belka, Alexander Golant, Robert D. Cardiff, Lewis A. Chodosh
Complement facilitates early prion pathogenesis.(Statistical Data Included)HealthHans Acha-Orbea, Adriano Aguzzi, Mark J. Walport, Marina Botto, Michael A. Klein, Pascal S. Kaeser, Petra Schwarz, Heiko Weyd, Ioannis Xenarious, Rolf M. Zinkernagel, Michael C. Carroll, J. Sjef Verbeek, Hector Molina, Ulrich Kalinke
Connecting Fanconi anemia to BRCA1.(disease genetics)HealthHans Joenje, Fre Arwert
COX-2 as a multifunctional neuronal modulator.HealthNicolas G. Bazan
Cyclic ADP-ribose production by the CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is requited for bacterial clearance 'in vivo'.(Statistical Data Included)HealthDebra A. Cockayne, Simon Monard, Santiago Partida-Sanchez, Elaine L. Jacobson, Norman Oppenheimer, Beth Garvy, Kim Kusser, Stephen Goodrich, Maureen Howard, Allen Harmsen, Troy D. Randall, Frances E. Lund
CYP3A genetics in drug metabolism.(CYP3A enzymes, which metabolize drugs)HealthMichel Eichelbaum, Oliver Burk
Cystic fibrosis salt/fluid controversy: In the thick of it.HealthWilliam B. Guggino
Death by influenza virus protein.HealthRobert A. Lamb, Makoto Takeda
Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.HealthPierre Savi, Jean-Marc Herbert, Peter Carmeliet, Anne Angelillo-Scherrer, Pablo Garcia de Frutos, Cristina Aparicio, Els Melis, Florea Lupu, Jef Arnout, Mieke Dewerchin, Marc F. Hoylaerts, Desire Collen, Bjorn Dahlback
Dendritic cells: on the move from bench to bedside.HealthFrank O. Nestle, Jacques Banchereau, Derek Hart
Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation.(Statistical Data Included)HealthFrancisco Garcia Soriano, Laszlo Virag, Prakash Jagtap, Eva Szabo, Jon G. Mabley, Lucas Liaudet, Anita Marton, Dale G. Hoyt, Kanneganti G.K. Murthy, Andrew L. Salzman, Garry J. Southan, Csaba Szabo
Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory.HealthMichael B.A. Oldstone, Dirk Homann, Luc Teyton
Differentiation or leukemia: is C/EBP(alpha) the answer?HealthScott Hiebert
Direct isolation and sequencing of specific protein-binding glycosaminoglycans.(Statistical Data Included)HealthNishla Keiser, Ganesh Venkataraman, Zachary Shriver, Ram Sasisekharan
Disruption of Akt kinase activation is important for immunosuppression induced by measles virus.(Statistical Data Included)HealthLawrence P. Kane, Elita Avota, Andris Avots, Stefan Niewiesk, Ursula Bommhardt, Volker ter Meulen, Sibylle Schneider-Schaulies
Downregulation of bacterial peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator.HealthDilara Islam, Lisa Bandholtz, Jakob Nilsson, Hans Wigzell, Birger Christensson, Birgitta Agerberth, Gudmundur H. Gudmundsson
Embryonic stem cell research: the case against.HealthMichael Antoniou
Embryonic stem cell research: the case for.HealthRobert Winston
Endocannabinoids acting at vascular CB (sub)1 receptors mediate the vasodilated state in advanced liver cirrhosis.(Statistical Data Included)HealthSravan K. Goparaju, Sandor Batkai, Zoltan Jarai, George Kunos, Jens A. Wagner, Karoly Varga, Jie Liu, Lei Wang, Faridoddin Mirshahi, Atmaram D. Khanolkar, Alexandros Makriyannis, Renata Urbaschek, Nelson Garcia Jr., Arun J. Sanyal
Epilepsy and all that jazz.HealthRam S. Puranam, James O. McNamara
Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli.(Statistical Data Included)HealthTabitha Springall, Neil S. Sheerin, Katsushige Abe, V. Michael Holers, Hong Wan, Steven H. Sacks
Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastic suppressor Nm23-H1: A molecular link to cancer metastasis.(Statistical Data Included)HealthChitra Subramanian, Murray A. Cotter II, Erle S. Robertson
Europe to standardize bacterial research.HealthTony Sheldon
Evasion in human innate and acquired immunity by a bacterial homolog of CD11b that inhibits opsonophagocytosis.HealthJames M. Musser, Benfang Lei, Frank R. DeLeo, Nancy P. Hoe, Morag R. Graham, Stacy M. Mackie, Robert L. Cole, Mengyao Liu, Harry R. Hill, Donald E. Low, Michael J. Federle, June R. Scott
Excitotoxic destruction facilitates brain tumor growth.HealthJeffrey D. Rothstein, Henry Brem
Eyeing a new route along an old pathway.(molecular causes for glaucoma)HealthStanislav I. Tomarev
Fanconi anemia group C protein prevents apoptosis in hematopietic cells through redox regulation of GSTP1.(Statistical Data Included)HealthRobert C. Cumming, Jeff Lightfoot, Kristin Beard, Hagop Youssoufian, Peter J. O'Brien, Manuel Buchwald
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells.HealthKenneth W. Kinzler, Bert Vogelstein, Timothy A. Chan, Paul M. Hwang, Jian Yu, Fred Bunz, Carlo Rago, Michael P. Murphy, Geoffry F. Kelso, Robin A. J. Smith
Fighting tobacco dependence in Europe.(Statistical Data Included)HealthMartin Raw
Forbidden fruit.(health aspects of citrus fruits)HealthJ.K. Aronson
From angiogenesis to lymphangiogenisis.(anticancer therapy)HealthKarl H. Plate
Functional alpha(sub)4-integrin: a newly identified pathway of neutrophil recruitment in critically ill septic patients.(Statistical Data Included)HealthGeoffrey C. Ibbotson, Christopher Doig, Jaswinder Kaur, Varinder Gill, Lena Ostrovsky, Todd Fairhead, Paul Kubes
Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo.HealthSunjay Kaushal, Gilad E. Amiel, Kristine J. Guleserian, Oz M. Shapira, Tjorvi Perry, Fraser W. Sutherland, Elena Rabkin, Adrian M. Moran, Frederick J. Schoen, Anthony Atala, Shay Soker, Joyce Bischoff, John E. Mayer Jr.
Gazing into a crystal ball - cancer therapy in the post-genomic era.HealthMark J. Ratain, Mary V. Relling
Generation of HIV latency during thymopoiesis.HealthDavid G. Brooks, Scott G. Kitchen, Christina M.R. Kitchen, Deirdre D. Scripture-Adams, Jerome A. Zack
Genetic models for CNS inflammation.(central nervous system)Health 
Getting the T-box dose right.(model of Holt-Oram syndrome)HealthCraig T. Basson, Cathy J. Hatcher
Glutamate release promotes growth of malignant gliomas.HealthMaiken Nedergaard, Tahakiro Takano, Jane H.-C. Lin, Gregory Arcuino, Qun Gao, Jay Yang
Heading off a web of deceit.(data security on the Internet)Health 
Helping the heart to heal with stem cells.HealthNadia Rosenthal, Lana Tsao
Heme oxygenase-1 protects against vascular constriction and proliferation.(Statistical Data Included)HealthElizabeth G. Nabel, Gary J. Nabel, Henricus J. Duckers, R. Clinton Webb, Manfred Boehm, Andrea L. True, Shaw-Fang Yet, Hong San, James L. Park, Mu-En Lee
Heparin-binding protein (HBP/CAP37): a missing link in neutrophil-evoked alteration of vascular permeability.HealthNarinder Gautam, A. Maria Olofsson, Heiko Herwald, Lars F. Iversen, Evy Lundgren-Akerlund, Per Hedqvist, Karl -E. Afros, Hans Flodgaard, Lennart Lindbom
Hepatitis-B virus endemicity: heterogeneity, catastrophic dynamics and control.(Statistical Data Included)HealthGraham Medley, Nathan A. Lindor, W. John Edmunds, D. James Nokes
Hepatitis C virus replication in mice with chimeric human livers.HealthNorman M. Kneteman, David F. Mercer, Daniel E. Schiller, John F. Elliott, Donna N. Douglas, Chunhai Hao, Rinfret Aline, William R. Addison, Karl P Fischer, Thomas A Churchill, Jonathan R.T Lakey, David L.J Tyrrell
Hereditary prostate cancer: a new piece of the puzzle.HealthAke Borg
HHMI to improve teaching.(Howard Hughes Medical Institute)HealthStephanie Irvine
High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide sythase.(Statistical Data Included)HealthIvan S. Yuhanna, Yan Zhu, Blair E. Cox, Lisa D. Hahner, Sherri Osborne-Lawrence, Ping Lu, Yves L. Marcel, Richard G.W. Anderson, Michael E. Mendelsohn, Helen H. Hobbs, Philip W. Shaul
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes.HealthMyoung Sook Kim, Ho Jeong Kwon, You Mie Lee, Jin Hyen Baek, Jae-Eun Jang, Sae-Won Lee, Eun-Joung Moon, Hae-Sun Kim, Seok-Ki Lee, Hae Young Chung, Chul Woo Kim, Kyu-Won Kim
Hitting the reset button for immune tolerance.HealthAllan D. Kirk
HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress.HealthJuan Martin-Serrano, Trinity Zang, Paul D. Bieniasz
HIV-1 and Ebola virus: the gateway driver nabbed.HealthJeremy Luban
HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals.(Statistical Data Included)HealthDietlinde Wolf, Vanessa Witte, Bernd Laffert, Katja BLume, Elisabeth Stromer, Susanna Trapp, Paola D'Aloja, Annette Schurmann, Andreas S. Bauer
HIV protease inhibitor apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia.HealthDavid A. Cooper, Jun-Shan Liang, Oliver Distler, Haris Jamil, Richard J. Deckelbaum, Henry N. Ginsberg, Stephen L. Sturley
Hope in the modern plague.(AIDS vaccine research)Health 
Host bone-marrow cells are a source of donor intimal smooth-muscle-like cells in murine aortic transplant arteriopathy.(Statistical Data Included)HealthElena Rabkin, Koichi Shimizu, Seigo Sugiyama, Masanori Aikawa, Yoshihiro Fukumoto, Peter Libby, Richard N. Mitchell
Hot on the TRAIL of acute promyelocytic leukemia.(Apo-2L/tumor necrosis factor-related apoptosis-inducing ligand)HealthArthur Zelent
How neutrophils recognize bacteria and move toward infection.HealthStaffan Normark, Birgitta Henriques Normark, Mathias Hornef
HPV vaccine moves into late stage trials.(human papillomavirus)HealthHarold Connet
Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor.(Statistical Data Included)HealthSheau Yu Hsu, Aaron J. W. Hsueh
IL-15 and IL-2: a matter of life and death for T cells 'in vivo'.(interleukin)(Statistical Data Included)HealthXian Chang Li, Gulcin Demirci, Sylvie Ferrari-Lacraz, Chris Groves, Anthony Coyle, Thomas R. Malek, Terry B. Strom
Imaging human epithelial properties with polarized light-scattering spectroscopy.(Statistical Data Included)HealthRajan S. Gurjar, Vadim Backman, Lev T. Perelman, Irene Georgakoudi, Kamran Badizadegan, Irving Itzkan, Ramachandra R. Dasari, Michael S. Feld
Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues.HealthMarkus Stoeckli, Pierre Chaurand, Dennis E. Hallahan, Richard M. Caprioli
Imaging metalloproteinase activity in vivo.HealthJian Cao, Stanley Zucker
Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.HealthDale Schenk, Brian J. Backsai, Stephen T. Kajdasz, Richard H. Christie, Cordelia Carter, Dora games, Peter Seubert, Bradley T. Hyman
Immune-mediated eradication of tumors through the blockage of transforming growth factor-beta signaling in T cells.HealthRichard A. Flavell, Leonid Gorelik
Immune privilege or inflammation: insights into the fas ligand enigma.(Statistical Data Included)HealthJoe O'Connell, Aileen Houston, Michael W. Bennett, Gerald C. O'Sullivan, Fergus Shanahan
Immunity or tolerance: opposite outcomes of microchimerism from skin grafts.(Statistical Data Included)HealthColin C. Anderson, Polly Matzinger
Impaired prostate tumorigenesis in EGr1-deficient mice.(early growth response protein 1)(Statistical Data Included)HealthJeffrey I. Gordon, Sarki A. Abdulkadir, Zhican Qu, Emily Garabedian, Sheng-Kwei Song, Thomas J. Peter, John Svaren, Joseph M. Carbone, Cathy K. Naughton, William J. Catalona, Joseph J.H. Ackerman, Peter A. Humphrey, Jeffrey Milbrandt
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth.(Statistical Data Included)HealthMalcolm A.S. Moore, Ronald G. Crystal, Robert Benezra, Yan Wu, David Lyden, Koichi Hattori, Sergio Dias, Carla Costa, Pamela Blaikie, Linda Butros, Amy Chadburn, Beate Heissig, Willy Marks, Larry Witte, Daniel Hicklin, Zhenping Zhu, Neil R. Hackett, Katherine A. Hajjar, Katia Manova, Shahin Rafii
Impaired replication of protease inhibitor-resistant HIV-1 in human thymus.(Statistical Data Included)HealthSteven G. Deeks, Joseph M. McCune, Robert M. Grant, Cheryl A. Stoddart, Teri J. Liegler, Fabrizio Mammano, Valerie D. Linquist-Stepps, Matthew S. Hayden, Francoise Clavel
Increased AT (sub)1 receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness.HealthSaid AbdAlla, Heinz Lother, Ursula Quitterer, Adel El Massiery
Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis.(interleukin)(Statistical Data Included)HealthJan Andersson, Steven G. Deeks, Joseph M. McCune, Robert M. Grant, Laura A. Napolitano, Diane Schmidt, Stephen C. De Rosa, Leonore A. Herzenberg, Brian G. Herndier
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.HealthJean Y.J. Wang, Paolo Vigneri
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis.Health 
Inflammation and Alzheimer disease: the good, the bad, and the ugly.HealthBruce A. Yankner, Stacie C. Weninger
Inhaled CO: deadly gas or novel therapeutic?(carbon monoxide)HealthChristoph Thiemermann
Inhibition of HIV-1 virion production by a transdominant mutant of integrase interactor 1.HealthDavid Ott, Eric Yung, Masha Sorin, Achintya Pal, Errol Craig, Alexe Morozov, Olivier Delattre, John Kappes, Ganjam V. Kalpana
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.HealthDavid G. Jackson, Shin-ichi Nishikawa, Hajime Kubo, Taija Makinen, Lotta Jussila, Tanja Veikkola, Terhi Karpenen, Mikko I. Kettunen, Kalevi J. Pulkkanen, Risto Kauppinen, Seppo Yla-Herttuala, Kari Alitalo
Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy.(Statistical Data Included)HealthSteven D. Shapiro, Ben Wielockx, Katrien Lannoy, Itohara Shigeyoshi, Itoh Takeshi, Joel Vandekerckhove, Claude Libert
Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28-/- mice.(Statistical Data Included)HealthStefan Maier, Christine Tertilt, Klaus Gerauer, Norbert Huser, Claus-Dieter Heidecke, Nicole Chambron, Klaus Pfefffer
Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28-/- mice.(Statistical Data Included)HealthStefan Maier, Christine Tertilt, Klaus Gerauer, Norbert Huser, Claus-Dieter Heidecke, Klaus Pfeffer, Nicole Chambron
Inhibition of the natural killer cells results in acceptance of cardiac allografts in CD28 (super)-/- mice.HealthStefan Maier, Christine Tertilt, Klaus Gerauer, Norbert Huser, Claus-Dieter Heidecke, Klaus Pfeffer, Nicole Chambron
Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses.HealthNora Sarvetnick, Cecile King, Regula Mueller Hoenger, Mary Malo Cleary, Kaja Murali-Krishna, Rafi Ahmed, Ernest King
Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.HealthIkuya Nonaka, Atsuo Ogura, Kazuto Nakada, Kimiko Inoue, Tomoko Ono, Kotoyo Isobe, Yu-Ichi Goto, Jun-Ichi Hayashi
Inviting leukemic cells to waltz with the devil.HealthJunia V. Melo
In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice.HealthLuigi Naldini, Antonella Consiglio, Angelo Quattrini, Sabata Martino, Jean Charles Bensadoun, Diego Dolcetta, Alessandra Trojani, Giuliana Benaglia, Sergio Marchesini, Vincenzo Cestari, Alberto Oliverio, Claudio Bordignon
'In vivo' measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy.(Statistical Data Included)HealthRakesh K. Jain, Peter Carmeliet, Edward B. Brown, Robert B. Campbell, Yoshikazu Tsuzuki, Lei Xu, Dai Fukumura
In vivo molecular target assessment of matrix metalloproteinase inhibition.(Statistical Data Included)HealthRalph Weissleder, Christoph Bremer, Ching-Hsuan Tung
In vivo optical mapping of epileptic foci and surround inhibition in ferret cerebral cortex.HealthTheodore H. Schwartz, Tobias Bonhoeffer
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.(Statistical Data Included)HealthKazuyoshi Takeda, Yoshihiro Hayakawa, Mark J. Smyth, Nobuhiko Kayagaki, Noriko Yamaguchi, Shigeru Kakuta, Yoichiro Iwakura, Hideo Yagita, Ko Okumura
Isolation of primary HIV-1 that target CD8+ T lymphocytes using CD8 as a receptor.(Statistical Data Included)HealthAnil Gupta, Kunal Saha, Jianchao Zhang, Rajnish Dave, Meron Yimen, Bouchra Zerhouni
Is tissue plasminogen activator a threat to neurons?HealthStephen F. Traynelis, Stuart A. Lipton
Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis.(Statistical Data Included)HealthLiza Makowski, Jeffrey B. Boord, Kazuhisa Maeda, Vladimir R. Babaev, K. Teoman Uysal, Maureen A. Morgan, Rex A. Parker, Jill Suttles, Sergio Fazio, Gokhan S. Hotamisligil, MacRae F. Linton
Laskers for 2001: knockout mice and test-tube babies.HealthJoseph L. Goldstein
Legal issues in genomic medicine.HealthPhillip R. Reilly
Less is more? STI in acute and chronic HIV-1 infection.(supervised treatment interruption)HealthMarcus Altfeld, Bruce D. Walker
Lethality-based selection of recombinant genes in mammalian cells: application to identifying tumor antigens.HealthErnest S. Smith, Aparna Mandokhot, Elizabeth E Evans, Loretta Mueller, Melinda A. Borrello, Deepak M. Sahasrabudhe, Maurice Zauderer
Life after death: controlling autoreactive CD8 (super)+ T-cell responses.HealthThomas J. Braciale
Linking ubiquitin, parkin and synphilin-1.HealthAaron Ciechanover
Lysosomal ceroid depletion by drugs: therapeutic implications for a hereditary neurodegenerative disease of childhood.HealthZhongjian Zhang, Jean DeB. Butler, Sondra W. Levin, Krystyna E. Wisniewski, Susan S. Brooks, Anil B. Mukherjee
Mbeki disputes AIDS statistics.(South African President Thabo Mbeki)HealthMichael Cherry
MHC-I-restricted presentation of HIV-1 virion antigens without viral replication.(Statistical Data Included)HealthFlorence Buseyne, Sylvie Le Gall, Clair Boccaccio, Jean-Pierre Abastado, Jeffrey D. Lifson, Larry O. Arthur, Yves Riviere, Jean-Michael Heard, Olivier Schwartz
Microarrays- the 21st century divining rod.HealthYudong D. He, Stephen H. Friend
Might mammalian mitochondria merge?.HealthDouglass M. Turnbull, Robert N. Lightowlers
Minor antigen solves major problem.(H antigen to treat leukemia)HealthJohn M. Goldman, Francesco Dazzi, Elizabeth Inchbald
Molecular targets for breast cancer therapy and prevention.HealthAxel Ullrich, Johannes Bange, Esther Zwick
Mouse gene targeting: fourty years with homologous recombination.(Lasker Basic Medical Research Award: Martin J. Evans, Oliver Smithies, Mario R. Capecchi)HealthOliver Smithies
Mouse gene targeting:generating mice with targeted mutations.(Lasker Basic Medical Research Award: Martin J. Evans, Oliver Smithies, Mario R. Capecchi)HealthMario R. Capecchi
Mouse gene targeting: the cultural mouse.(Lasker Basic Medical Research Award: Martin J. Evans, Oliver Smithies, Mario R. Capecchi)HealthMartin J. Evans
MTV honors AIDS campaigners.HealthJohn MacFarlane
Much ado about data.(Editorial)Health 
Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques.HealthZdenek Hel, Ruth Woodward, Genoveffa Franchini, Todd M. Allen, Alessandro Sette, David I. Watkins, Warren Strober, Igor M. Belyakov, Brian Kelsall, Vladimir A. Kuznetsov, Jeffrey D. Ahlers, Janos Nacsa, John Altman, Phillip D. Markham, John D. Clements, Jay A. Berzofsky
Multiplex PCR by multicolor fluorimetry and fluorescence melting curve analysis.(polymerase chain reaction)HealthKojo S.J. Elenitoba-Johnson, Sandra Bohling, Carl T. Wittwer, Thomas C. King
Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function.HealthJ. Wang, A. A. Kocher, M.D. Schuster, M.J. Szablocs, S. Takuma, D. Burkhoff, S. Homma, N.M. Edwards, S. Itescu
Neural stem cells- where are you?HealthJack Price
New agents to combat malaria.HealthJames G. Beeson, Graham V. Brown, Peter Winstanley, Geoffrey McFadden
New TB vaccines to be tested.(tuberculosis)HealthJeremy Thomson
Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis.(Statistical Data Included)HealthChristopher Heeshcen, James J. Jang, Michael Weis, Anjali Pathak, Shuichiro Kaji, Robert S. Hu, Philip S. Tsao, Frances L. Johnson, John P. Cooke
Nimble progenitors rescue vascular grafts.HealthDavid Mooney
Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent.HealthMing Zhao, Daniel A. Beauregard, Louiza Loizou, Bazbek Davletov, Kevin M. Brindle
NO, SNO and low O (sub)2.(nitric oxide)(S-nitrosothiol)HealthJose M. Mato, Matias A. Avila, Fernando J. Corrales
NO vascular control in Duchenne muscular dystrophy.HealthRachelle H. Crosbie
NSAIDs inhibit (alpha)V(beta)3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.(nonsteroidal anti-inflammatory drugs)HealthOlivier Dormond, Alessandro Foletti, Cecile Paroz, Curzio Ruegg
ORP150 protects against hypoxia/ischemia-induced neuronal death.(Statistical Data Included)HealthHideki Yanagi, David M. Stern, Michio Tamatani, Tomohiro Matsuyama, Atsushi Yamaguchi, Noriaki Mitsuda, Yoshitane Tsukamoto, Manabu Taniguchi, Yong Ho Che, Kentaro Ozawa, Osamu Hori, Hiroyuki Nishimura, Atsuko Yamashita, Masaru Okabe, Satoshi Ogawa, Masaya Tohyama
Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection.(Statistical Data Included)HealthIvor N. Brown, Douglas B. Young, Joanna Betts, Graham R. Stewart, Valerie A. Snewin, Gerhard Walzl, Tracy Hussell, Peter Tormay, Peadar O'Gaora, Madhu Goyal
Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis.(Statistical Data Included)HealthShi-Fang Yan, Fujita Tomoyuki, Toda Koichi, Ann Karimova, Yoshifumi Naka, Shaw-Fang Yet, David Pinsky
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications of Lewy-body formation in Parkinson disease.(Statistical Data Included)HealthTed M. Dawson, Yi Zhang, Kenny K. K. Chung, Kah Leong Lim, Yuji Tanaka, Hui Huang, Jun Gao, Christopher A. Ross, Valina L. Dawson
Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability.(Statistical Data Included)HealthKang Chen, Ildiko Aradi, Niklas Thon, Mariam Eghbal-Ahmadi, Tallie Z. Baram, Ivan Soltesz
Pharmacogenetic applications of the human genome project.HealthStephen B. Liggett
Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis.HealthReinhard Fassler, Takao Sakai, Kamin J. Johnson, Michihiro Murozono, Keiko Sakai, Marc A. Magnuson, Tadeuz Wieloch, Tobias Cronberg, Atsushi Isshiki, Harold P. Erickson
Plugging the leaks.HealthKlaus Ley
Polio eradication: the endgame.(Editorial)HealthBeatrice Renault
Polyglutamine and CBP: fatal attraction?(CREB-binding protein)HealthAlexander McCampbell, Kenneth H. Fischbeck
Positron emission tomography imaging for herpes virus infection: implications for oncolytic viral treatments of cancer.(Statistical Data Included)HealthJoseph J. Bennett, Juri Tjuvajev, Paul Johnson, Mikhail Doubrovin, Timothy Akhurst, Sandeep Malholtra, Trevor Hackman, Julius Balatoni, Ronald Finn, Steven M. Larson, Howard Federoff, Ronald Blasberg, Yuman Fong
Possible new role for NF-kB in the resolution of inflammation.(nuclear factor)HealthDerek A. Willoughby, Paul R. Colville-Nash, Toby Lawrence, Derek W. Gilroy
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.(peroxisome proliferator-activated receptors)(Statistical Data Included)HealthGiulia Chinetti, Sophie Lestavel, Virginie Bocher, Alan T. Remaley, Bernadette Neve, Ines Pineda Torra, Elisabeth Teissier, ANne Minnich, Michael Jaye, Nicolas Duverger, H. Bryan Brewer, Jean-Charles Fruchart, Veronique Clavey, Bart Staels
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation.(peroxisome proliferator-activated receptor)(Statistical Data Included)HealthRonald M. Evans, Ajay Chawla, Yaacov Barak, Laszlo Nagy, Debbie Liao, Peter Tontonoz
Predicting the unpredictable: transmission of drug-resistant HIV.HealthS. M. Blower, A. N. Aschenbach, H. B. Gershengorn, J. O. Kahn
Profiling familial breast cancer.HealthSunil R. Lakhani, Michael J. O'Hare, Alan Ashworth
Progress in cardiovascular biology: PPAR for the course.(peroxisome proliferator-activated receptor)HealthMitchell A. Lazar
Promiscuous regulator of xenobiotic removal.HealthErin Schuetz, Stephen Strom
Prospects for Parkinson disease.Health 
Protection of rhesus macaques against disease progression from pathogenic SHIV-89.6PD by vaccination with phage-displayed HIV-1 epitopes.(Statistical Data Included)HealthMark G. Lewis, Tae-Wook Chun, J. Shawn Justement, Anthony S. Fauci, David Venzon, Xueni Chen, Giuseppe Scala, Ileana Quinto, Weimin Liu, Oren J. Cohen, Tom C. VanCott, Marcin Iwanicki, Jack Greenhouse, Todd Barry
Proteinase-activated receptor-2 and hyperalgesia: a novel pain pathway.(Statistical Data Included)HealthN. Vergnolle, M.D. Hollenberg, J.L. Wallace, N.W. Bunnett, K.A. Sharkey, V. Brusse, S.J. Compton, E.F. Grady, G. Cirino, N. Gerard, A.I. Basbaum, P. Andrade-Gordon
Protein-based PCR for prion diseases?(polymerase chain reaction)HealthGlenn Telling
Putting the genes for type II diabetes on the map.HealthC. Ronald Kahn, Katrine Almind, Allessandro Doria
Rapid anthrax test developed.HealthSarah Cooney
Real-time imaging of apoptotic cell-membrane changes at the single-cell level in the beating murine heart.HealthE. A. Dumont, C. P. M. Reutelingsperger, J. F. M. Smits, M. J. A. P. Daemen, P. A. F. Doevendans, H. J. J. Wellens, L. Hofstra
Receptor double-trouble in preeclampsia.HealthDavid Lodwick
Regulation of pancreatic beta-cell growth and survival by the serine/threonine kinase Akt1/PKB(alpha).(Statistical Data Included)HealthEmma E. Furth, Morris J. Birnbaum, Kenneth S. Polonsky, Robyn L. Tuttle, Navdeep S. Gill, William Pugh, Jean-Pyo Lee, Brigitte Koeberlein, Ali Naji
Replication-selective virotherapy for cancer: biological principles, risk management and future directions.HealthDavid Kirn, Robert L. Martuza, James Zwiebel
Research news.HealthKristine Novak, Leila Alland
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.(tumor necrosis factor-related apoptosis-inducing ligand)(Statistical Data Included)HealthLucia Altucci, Aurelie Rossin, Wolfgang Raffelsberger, Armin Reitmair, Christine Chomienne, Hinrich Gronemeyer
SADS: a new component of Fas-DISC is the accelerator for cell death signaling and is downregulated in patients with colon carcinoma.(Fas-death inducing signaling complex)(Statistical Data Included)HealthHirokazu Kawano, Midori Hayashida, Atsushi Suzuki, Shigehiro Obata, Takeshi Nakano, Katsuya Shiraki
SCAP ligands are potent new lipid-lowering drugs.(sterol cleavage-activating protein)HealthThierry Grand-Perret, Anne Bouillot, Aurelie Perrot, Stephane Commans, Max Walker, Marc Issandou
Scientists race to develop a blood test for vCJD.(variant Creutzfeldt-Jakob disease)Health 
Seeing death in the living.HealthRoberta A. Gotlieb, Richard N. Kitsis
Sensory neurons are PARtial to pain.(proteinase-activated receptor)Health 
Shigekazu Nagata.(biomedical scientist)HealthDavid Cyranoski
'Shigellae' control the gates of LL.(antibacterial peptides)HealthRobert I. Lehrer
Signaling through 0X40 (CD134) breaks peripheral T-cell tolerance.HealthPratima Bansal-Pakala, Amha Gebre-Hiwot Jember, Michael Croft
Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke.HealthRobert Paul, Zheng G. Zhang, Brian P. Eliceiri, Quan Jian, Antonio D. Boccia, Rui L. Zhang, Michael chopp, David A. Cheresh
Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site.(Statistical Data Included)HealthGabriele Weitz-Schmidt, Karl Welzenbach, Volker Brinkmann, Tetsji Kamata, Joerg Kallen, Christian Bruns, Sylvain Cottens, Yoshikazu Takada, Ulrich Hommel
Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells.HealthDavid T. Curiel, Weiping Zou, Veronique Machelon, Aurore Coulomb-L'Hermin, Jozef Borvak, Francoise Nome, Tatyana Isaeva, Shuang Wei, Roman Krzysiek, Ingrid Durand-Gasselin, Alan Gordon, Terri Pustilnik, Pierre Galanaud, Frederique Capron, Dominique Emilie, Tyler J. Curiel
Subtelomeric chromosome rearrangements are detected using an innovative 12-color FISH assay (M-TEL).(fluorescence in situ hybridization)HealthJill Brown, Kaan Saracoglu, Sabine Uhrig, Michael R. Speicher, Roland Eils, Lyndal Kearney
Suppression of CCR5- but not CXCR4-trophic HIV-1 in lymphoid tissue by human herpesvirus 6.(Statistical Data Included)HealthJean-Charles Grivel, Ito Yoshinori, Giovanni Faga, Fabio Santoro, Farida Shaheen, Mauro S. Malnati, Wendy Fitzgerald, Paolo Lusso, Leonid Margolis
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.(Statistical Data Included)HealthJean-Marc Herbert, Peter Carmeliet, Karl H. Plate, Mieke Dewerchin, Lieve Moons, M. Graziella Persico, Aernout Luttun, Valeria Vincenti, Verle Compernolle, Maria De Mol, Yan Wu, Francoise Bono, Laetitia Devy, Heike Beck, Dimitri Scholz, TIll Acker, Tina DiPalma, Agnes Noel, Ingeborg Stalmans, Adriano Barra, Sylvia Blacher, Theirry Vandendriessche, Annica Ponten, Ulf Eriksson, Jean-Michel Foidart, Wolfgang Schraper, D. Stephen Charnock-Jones, Daniel J. Hicklin, Desire COllen
Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle.(Statistical Data Included)HealthMylene Perreault, Andre Marette
Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels.(Statistical Data Included)HealthValentin K. Gribkoff, John E. Jr. Starrett, Steven I. Dwortezky, Piyasena Hewawasam, Christopher G. Boissard, Deborah A. Cook, Stephen W. Frantz, Karen Heman, Jeffrey R. Hibbard, Kevin Huston, Graham Johnson, Bala S. Krishnan, Gene G. Kinney, Lynn A. Lombardo, Nicholas A. Meanwell, Perry B. Molinoff, Robert A. Myers, Sandra L. Moon, Astrid Ortiz, Lorraine Pajor, Rick L. Pieschl, Debra J. Post-Munson, Laura J. Signor, Nugehally Srinvas, Matthew T. Taber, George Thalody, Joanne T. Trojnacki, Harvey Wiener, Krishnaswamy Yeleswaram, Sarita W. Yeola
Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.HealthJosef Priller, Alexander Flugel, Tim Wehner, Matthias Boentert, Carola A. Haas, Marco Prinz, Francisco Fernandez-Klett, Konstantin Prass, Ingo Bechmann, Bauke A. de Boer, Michael Frotscher, Georg W. Kreutzberg, Derek A. Persons, Ulrich Dirnagl
TB comes to a sticky beginning.HealthDavid G. Russell
T-cell release of granulysin contributes to host defense in leprosy.HealthRobert L. Modlin, Maria-Teresa Ochoa, Steffen Stenger, Peter A. Sieling, Sybille Thoma-Uzynski, Shereen Sabet, Sungae Cho, Alan M. Krensky, Martin Rollinghoff, Euzenir Nunes Sarno, Anne E. Burdick, Thomas H. Rea
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.HealthMoira E. Bruce, Mark J. Walport, Neil A. Mabbott, Marina Botto, Mark B. Pepys
TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.(transforming growth factor)(Statistical Data Included)HealthLennart Mucke, Tony Wyss-Coray, Lisa McConlogue, Carol Lin, Fengrong Yan, Gui-Qiu Yu, Michelle Rohde, Eliezer Masliah
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype.HealthSheng Zhou, John D. Schuetz, Kevin D. Bunting, Anne-Marie Colapietro, Janardhan Sampath, John J. Morris, Irina Lagutina, Gerard C. Grosveld, Mitsujiro Osawa, Hiromitsu Nakauchi, Brian P. Sorrentino
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action.HealthMichael Brownlee, Anders H. Berg, Terry P. Combs, Xueliang Du, Philipp E. Scherer
The allogeneic response and tumor immunity.HealthJohn W. Fabre
The alternative to penicillins.HealthJoachim-Volker Holtje
The analysis of costimulatory receptor signaling cascades in normal T lymphocytes using in vitro gene transfer and reporter gene analysis.(Statistical Data Included)HealthMichael P. Bell, Catherine J. Huntoon, Daniel Graham, David J. McKean
The bumpy road to human in vitro fertilization.(Lasker Clinical Medical Research Award)HealthRobert Geoffrey Edwards
The cellular neurobiology of depression.HealthHusseini Manji, Wayne C. Drevets, Dennis S. Charney
The early days of DNA sequences.HealthFred Sanger
The economy of T-cell memory: CD4+ recession in times of CD8+ stability?HealthRafi Ahmed, Jason K. Whitmire
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.HealthT . Yamauchi, J. Kamon, H. Waki, Terauchi Y., Kubota N., K. Hara, Y. Mori, T. Ide, K. Murakami, N. Tsuboyama-Kasaoka, O. Ezaki, Y . Akanuma, O. Gavrilova, C. Vinson, Reitman M.L ., H. Kagechika, K . Shudo, M . Yoda, Y. Nakano, K . Tobe, R. Nagai, S. Kimura, M. Tomita, P . Froguel, T. Kadowaki
The heart of genomics.(genetic research and cardiac disease)HealthMichel Komajda, Philippe Charron
The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of antiogenic growth factors.(Statistical Data Included)HealthMarcy Silver, Marianne Kearney, Jeffrey M. Isner, Roberto Pola, Leona E. Ling, Michael J. Corbley, R. Blake Pepinski, Renee Shapiro, Frederick R. Taylor, Darren P. Baker, Takayuki Asahara
The natural history of HIV-1 infection in Africa.HealthDilys Morgan, Jimmy A.G. Whitworth
The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice.HealthDavid C. Scherer, Seokmann Hong, Michael T. Wilson, Isao Serizawa, Lan Wu, Nagendra Singh, Olga V. Naidenko, Toru Miura, Tomoku Haba, Jie Wei, Mitchell Kronenberg, Yasuhiko Koezuka, Luc van Kaer
The neglected ion: HCO3.(cystic fibrosis research)HealthPaul M. Quinton
The neurotransmitter dopamine inhibits angiogenesis induced by vascular permeability factor/vascular endothelial growth factor.(Statistical Data Included)HealthSujit Basu, Janice A. Nagy, Soumitro Pal, Isabelle A. Eckelhoefer, V. Susan Bliss, Eleanor J. Manseau, Partha S. Dasgupta, Harold F. Dvorak, Debabrata Mukhopadhyay, ELiza Vasile
The neurotransmitter dopamine inhibits angiogenesis induced by vasuclar permeability factor/vascular endothelial growth factor.(Statistical Data Included)HealthSujit Basu, Janice A. Nagy, Soumitro Pal, Eliza Vasile, Isabelle A. Eckelhoefer, V. Susan Bliss, Eleanor J. Manseau, Partha S. Dasgupta, Harold F. Dvorak, Debabrata Mukhopadhyay
The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux.(steroid xenobiotic receptor)(Statistical Data Included)HealthTimothy W. Synold, Isabelle Dussault, Barry Marc Forman
The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.(N-methyl-D-aspartate)(Statistical Data Included)HealthPeter Carmeliet, Olivier Nicole, Fabian Docagne, Carine Ali, Isabelle Margaill, Eric MacKenzie, Denis Vivian, Alain Buisson
Therapeutic opportunities in polyglutamine disease.HealthJames M. Olson, Robert E. Hughes
Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow.(Statistical Data Included)HealthMarkus Feuerer, Philipp Beckhove, Lianhua Bai, Erich-Franz Solomayer, Gunther Bastert, Ingo J. Diel, Claudia Pedain, Michael Oberniedermayr, Volker Schirrmacher, Victor Umansky
The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.(perixisome proliferator-activated receptor)HealthBruce M. Spiegelman, Evan D. Rosen, David Altshuler, Katheryn J. Moore, Michael L. Fitzgerald, Felix Randow, Lorna P. Andersson, David Milstone, Richard M. Mortensen, Mason W. Freeman
The vicious cyclin of addiction.(drug addiction and the nervous system)HealthFrancis J. White, Donald C. Cooper
The well-tempered vessel.(blood vessels)HealthHelen M. Blau, Andrea Banfi
The wonder that is global health.(Mary Woodard Lasker Award for Public Service)HealthWilliam H. Foege
Too many vessels? Not enough? The wrong kind? The VEGF debate continues.(vascular endothelial growth factor)HealthJ. Anthony Ware
TREM-1: a new regulator of innate immunity in sepsis syndrome.(triggering recpetor expressed on myeloid cells)HealthCarl Nathan, Aihao Ding
Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of 'Plasmodium falciparum'.HealthNamita Surolia, Avadhesha Surolia
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross priming.(cytotoxic T lymphocytes)(Statistical Data Included)HealthJoseph Wolfers, Anne Lozier, Graca Raposo, Armelle Regnault, Clotilde Thery, Carole Masurier, Caroline Flament, Stephanie Pouzieux, Florence Faure, Thomas Tursz, Eric Angevin, Sebastian Amigorena, Laurence Zitvogel
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.HealthWeimin Liu, Kimihsa Ichikawa, Limin Zhao, Zheng Wang, Di Liu, Toshiaki Ohtsuka, Huangge Zhang, John D Mountz, William J Koopman, Robert P. Kimberley, Tong Zhou
Tumor-specific gene expression in hepatic metastases by a replication-activated adenovirus vector.HealthDirk S. Steinwaerder, Cheryl A. Carlson, Desiree L. Otto, Zong-Yi Li, Shaoheng Ni, Andre Lieber
Turning WAT intp BAT gets rid of fat.(white adipose tissue)(brown adipose tissue)(Statistical Data Included)HealthRobert V. Farese Jr., Hubert C. Chen
UK cancer charities concerned about new EU regulations.HealthDavid Dickson
Ultrahigh-resolution ophthalmic optical coherence tomography.HealthJoel S. Schuman, Wolfgang Drexler, Uwe Morgner, Ravi K. Ghanta, Franz X. Kartner, James G. Fujimoto
Uncoupling protein 2: adiposity angel and diabetes devil?HealthStephen O'Rahilly
Vascular endothelial growth factor enhances atherosclerotic plaque progression.(Statistical Data Included)HealthFrancesca L. Celletti, Jacob M. Waugh, Philippe G. Amabile, Andrea Brendolan, Paul R. Hilfiker, Michael D. Dake
Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease.(Statistical Data Included)HealthMario Delgado, Cataline Abad, Carmen Martinez, Javier Leceta, Rosa P. Gomariz
Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease.(Statistical Data Included)HealthMario Delgado, Carmen Martinez, Javier Leceta, Rosa P. Gomariz, Catalina Abad
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics.HealthSteven A. Stacker, Carol Caesar, Megan E. Baldwin, Gillian E. Thornton, Richard A. Williams, Remko Prevo, David G. Jackson, Shin-ichi Nishikawa, Hajime Kubo, Marc G. Achen
VIP: a very important protein in arthritis.(vasoactive intestinal peptide)HealthGary S. Firestein
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics.HealthMark A. Kay, Joseph C. Glorioso, Luigi Naldini
VWF meets the ADAMTS family.(von Willebrand factor in throbotic thrombocytopenic purpura)HealthLawrence Brass
Watson's 'sun and sex' lecture upsets audience.(Nobel Laureate James Watson)Health 
Web bounty hunters chase research patients.HealthKathleen McGowan
Whole recombinant yeast vaccine activates dendritic cells and elicits protective cell-mediated immunity.(Statistical Data Included)HealthDaniel R. Kuritzkes, Andrew C. Stubbs, Kathleen S. Martin, Claire Coeshott, Serena V. Skaates, Donald Bellgrau, Alex Franzusoff, RIchard C. Duke, Cara C. Wilson
Will research be restricted by new data privacy rules ... and more oversight?HealthTinker Ready, Alicia Ault
Will the drugs still work? Transmission of resistant HIV.HealthAndrew Phillips
Will the U.S. clone alone?(Editorial)Health 
'Yersinia' lead SUMO attack.(pathogenic bacteria)HealthGuy R. Cornelis, Geertrui Denecker
You are what you secrete.HealthAlan R. Saltiel
Zeroing in on tolerance.(immune system ability)HealthAnne M. Bowcock, Michael Lovett
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