Cell 1999 - Abstracts
| Cell 1999 | |||||
| Title | Subject | Authors | |||
|---|---|---|---|---|---|
| 13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation. | Biological sciences | Nancy J. Crisona, Tatsuya Hirano, Nicholas R. Cozzarelli, Keiji Kimura, Valentin V. Rybenkov | |||
| Absence of BCL10 mutations in human malignant mesothelioma. | Biological sciences | Sinoula Apostolou, Assunta de Rienzo, Siva S. Murthy, Suresh C. Jhanwar, Joseph R. Testa | |||
| A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis. | Biological sciences | Marta Galova, Sara B.C. Buonomo, Kim Nasmyth, Peter Mahr, Franz Klein, Knud Nairz, Christine Michaelis | |||
| A coat protein on phagosomes involved in the intracellular survival of mycobacteria. | Biological sciences | Makoto Naito, Jean Pieters, Girogio Ferrari, Hanno Langen | |||
| Activation of store-operated Ca2+ current in Xenopus oocytes requires SNAP-25 but not a diffusible messenger. | Biological sciences | Roger Y. Tsien, Yong Yao, Antonio V. Ferrer-Montiel, Mauricio Montal | |||
| Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16(super INK4a), TGF-beta, and contact inhibition. | Biological sciences | Douglas C. Dean, Antonio A. Postigo, H. Steven Zhang | |||
| Adaptors and molecular scaffolds in immune cell signaling. | Biological sciences | Christopher E. Rudd | |||
| A detailed view of a ribosomal active site: the structure of the L11-RNA complex. | Biological sciences | V. Ramakrishnan, Stephen W. White, Rebecca Guymon, Brian T. Wimberley, John P. McCutcheon | |||
| A functional enhancer suppresses silencing of a transgene and prevents its localiztion close to centromeric heterochromatin.(Statistical Data Included) | Biological sciences | Claire Francastel, David I.K. Martin, Mark C. Walters, Mark groudine | |||
| Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor. | Biological sciences | Michael Z. Lin, Michael E. Greenberg, Michael J. Anderson, Karen C. Arden, John Blenis, Azad Bonni, Anne Brunet, Michael J. Zigmond, Peter Juo, Linda S. Hu | |||
| A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts Netrin-induced growth cone attraction to repulsion.(Deleted in Colorectal Cancer) | Biological sciences | Kyonsoo Hong, Makoto Nishiyama, Marc Tessier-Lavigne, Mu-ming Poo, Elke Stein, Lindsay Hinck | |||
| A map of pheromone receptor activation in the mammalian brain. | Biological sciences | Catherine Dulac, Richard Axel, Georgy Koentges, Leonardo Belluscio | |||
| A molecular mechanism regulating rhythmic output from the superchiasmatic circadian clock. | Biological sciences | Lauren P. Shearman, Steven M. Reppert, Mark J. Zylka, Xiaowei Jin, Geert J. De Vries | |||
| A molecular target for viral killer toxin: TOK1 potassium channels.(Statistical Data Included) | Biological sciences | Federico Sesti, Theodore M. Shih, Steve A.N. Goldstein, Stephen L. Sturley, Aamir Ahmed, Nitza Ilan | |||
| An auxin-dependent distal organizer of pattern and polarity in the Arabidopsis root.(Statistical Data Included) | Biological sciences | Sabrina Sabatini, Nicole Bechtold, Ottoline Leyser, Ben Scheres, Dimitris Beis, Tom Guilfoyle, Peter Weisbeek, Harald Wolkenfelt, Jane Murfett, Jocelyn Malamy, Philip Benfey | |||
| An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3. | Biological sciences | Anders Nykjaer, Christian Jacobsen, Thomas E. Willnow, Henrik Vorum, Duska Dragun, Joachim Herz, Diego Walther, Flemming Melsen, Erik Ilsoe Christensen | |||
| An engine for nucleosome remodeling. | Biological sciences | Andrew Travers | |||
| An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. | Biological sciences | Julie Huang, Danesh Moazed, Jason C. Tanny, Gustave J. Dowd, Helmuth Hilz | |||
| A new role for Glia: generation of neurons! | Biological sciences | Ben A. Barres | |||
| A novel cis-regulatory element, the PTS, mediates an anti-insulator activity in the Drosophila embryo.(Statistical Data Included) | Biological sciences | Michael Levine, Jumin Zhou | |||
| A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans.(Statistical Data Included) | Biological sciences | Paul Schulze-Lefert, Man-Wah Tan, Ken Shirasu, Thomas Lahaye, Fasong Zhou, Cristina Azevedo | |||
| A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells.(Statistical Data Included) | Biological sciences | Ira Mellman, Juan S. Bonifacino, Heike Folsch, Hiroshi Ohno | |||
| A novel role for 3-O(ital)-sulfated heparan sulfate in herpes simplex virus 1 entry.(Statistical Data Included) | Biological sciences | Robert D. Rosenberg, Deepak Shukla, Jeffrey D. Esko, Jian Liu, Gary H. Cohen, Roselyn J. Eisenberg, Patricia G. Spear, Peter Blaiklock, Nicholas W. Shworak, Xiaomei Bai | |||
| A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. | Biological sciences | Thorsten Hoppe, Helle D. Ulrich, Stefan Jentsch, Thomas U. Mayer, Manfred Koegl, Stephan Schlenker | |||
| Antagonistic signaling by Caronte (ital), a novel Cerberus (ital)-related gene, establishes left-right asymmetric gene expression. | Biological sciences | Clifford J. Tabin, Richard V. Pearse II, Yuji Yokouchi, Kyle J. Vogan | |||
| Antagonists go out on a limb. | Biological sciences | Denis Duboule, Thomas F. Vogt | |||
| A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioural circadian rhythms in Drosophila. | Biological sciences | Michael Rosbash, Susan C.P. Renn, Jae H Park, Jeffrey Hall C., Paul H. Taghert | |||
| A perfect message: RNA surveillance and nonsense-mediated decay. | Biological sciences | Matthias W. Hentze, Andreas E. Kulozik | |||
| A primer on vesicle budding. | Biological sciences | Randy Schekman, Anne Spang, Sebastian Springer | |||
| A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. | Biological sciences | Randal J. Kaufman, Peter Walter, Maho Niwa, Carmela Sidrauski | |||
| A Smad transcriptional corepressor. | Biological sciences | Joan Massague, Roger S. Lo, Susan Lee, David Wotton | |||
| A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventrals spinal cord. | Biological sciences | Thomas M. Jessell, Alessandra Pierani, Chin Chiang, usan Brenner-Morton | |||
| A spatial map of olfactory receptor expression in the Drosophila antenna. | Biological sciences | Leslie B. Vosshall, Richard Axel, Andrey Rzhetsky, Hubert Amrein, Pavel S. Morozov | |||
| A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. | Biological sciences | Neil J. McKenna, Bert W. O'Malley, Ming-Jer Tsai, Sophia Y. Tsai, Urs Albrecht, Sergio A. Onate, Rainer B. Lanz, Jiemin Wong | |||
| A striking organization of a large family of human neural cadherin-like cell adhesion genes. | Biological sciences | Tom Maniatis, Qiang Wu | |||
| A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain. | Biological sciences | David J. Owen, Yvonne Vallis, Harvey T. McMahon, Martin E.M. Noble, Philip R. Evans, Jack B. Hunter, Tim R. Dafforn | |||
| A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein. | Biological sciences | Christoph Spiess, Alexandra Beil | |||
| Atomic structure of scallop myosin subfragment S1 complexed with mgADP: a novel conformation of the myosin head. | Biological sciences | Carolyn Cohen, Anne Houdusse, Vassilios N. Kalabokis, Daniel Himmel, Andrew G. Szent-Gyorgyi | |||
| ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF.(nucleosome remodeling factor) | Biological sciences | Ali Hamiche, Carl Wu, David A. Gdula, Raphael Sandaltzopoulos | |||
| A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis.(Statistical Data Included) | Biological sciences | Eric R. Kandel, Dusan Bartsch, Andrea Casadio, Maurizio Giustetto, Huixiang Zhu, Mary Chen, Craig H. Bailey, Kelsey C. Martin | |||
| Attraction versus repulsion: modular receptors make the difference in axon guidance. | Biological sciences | Mark A. Seeger, Christine E. Beattie | |||
| A unified nomenclature for the nuclear receptor superfamily.(Letter to the Editor) | Biological sciences | ||||
| Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. | Biological sciences | Sean Oldham, Ernst Hafen, Juan Riesgo-Escovar, Kathy Beckingham, Ruth Bohni, Walter Brogiolo, Hugo Stocker, Bernard F. Andruss | |||
| A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity.(p300/CBP-associated factor) | Biological sciences | Hung-Ying Kao, Ronald M. Evans, Yoshihiro Nakatani, Debabrata Chakravarti, Vasily Ogryzko, Hongwu Chen, Alyssa Nash | |||
| Axis development and early asymmetry in mammals.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Elizabeth J. Robertson, Rosa S.P. Beddington | |||
| Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating. | Biological sciences | Henry A. Lester, Dennis A. Dougherty, Pamela M. England, Yinong Zhang | |||
| Bacterial disease in diverse hosts. | Biological sciences | B. Brett Finlay | |||
| Bc/10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.(mucosa-associated lymphoid tissue) | Biological sciences | Munah Abdul-Rauf, Peter G. Isaacson, Iwona Wlodarska, Tim Crook, Rifat Hamoudi, Tony G. Willis, Dalal M. Jadayel, Ming-Qing Du, Huaizheng Peng, Amanda R. Perry, Helen Price, Loraine Karran, Oluwatosin Majekodunmi, Langxing Pan, Martin J.S. Dyer | |||
| BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex.(brain-derived neurotrophic factor)(Statistical Data Included) | Biological sciences | Mark F. Bear, Susumu Tonegawa, Alfredo Kirkwood, Z. Josh Huang, Tommaso Pizzorusso, Vittorio Porciatti, Bernardo Morales, Lamberto Maffei | |||
| Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching. | Biological sciences | Marc Tessier-Lavigne, Thomas Kidd, Corey S. Goodman, Katja Brose, David Arnott, William Henzel, Kuan Hong Wang | |||
| BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane.(endoplasmic reticulum) | Biological sciences | Tom A. Rapoport, Kathrin Plath, Kent E. Matlack, Benjamin Misselwitz | |||
| Blobel's Nobel: a vision validated.(essay) | Biological sciences | Peter Walter, David Anderson | |||
| Breaking colinearity in the mouse HoxD complex. | Biological sciences | Denis Duboule, Takashi Kondo | |||
| Brefeldin A: the advantage of being uncompetitive. | Biological sciences | Frank McCormick, Pierre Chardin | |||
| Bridge over troubled waters: sensing stress by disulfide bond formation. | Biological sciences | Jon Beckwith, Fredrik Aslund | |||
| Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex.(Statistical Data Included) | Biological sciences | Yousif Shamoo, Thomas Steitz | |||
| Bulk flow redux? | Biological sciences | Ira Mellman, Graham Warren | |||
| Catch the micro1B train to the basolateral surface.(Statistical Data Included) | Biological sciences | Steven J. Chapin, Keith Mostov, Martin B.A. ter Beest | |||
| CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. | Biological sciences | Reinhold Forster, Martin Lipp, Elisabeth Kremmer, Eckhard Wolf, Andreas Schubel, Dagmar Breitfeld, Ingrid Renner-Muller | |||
| CD46 is a cellular receptor for human herpesvirus 6. | Biological sciences | Fabio Santoro, Mauro S. Malnati, Paolo Lusso, Giuseppe Locatelli, Paul E. Kennedy, Edward A. Berger | |||
| Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1.(Statistical Data Included) | Biological sciences | Douglas C. Dean, Robin X. Luo, Antonio A. Postigo, J. William Harbour, Santi Dei Angeline | |||
| Cell cycle-dependent polar localization of an essential bacterial histidine kinase that controls DNA replication and cell division. | Biological sciences | Lucy Shapiro, Christine Jacobs, Ibrahim J. Domian, Janine R. Maddock | |||
| Cell death in development.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Stanley J. Korsmeyer, David L. Vaux | |||
| Chaperone activity with a redox switch. | Biological sciences | Ursula Jakob, James C.A. Bardwell, Wilson Muse, Markus Eser | |||
| Chimeric axon guidance receptors: the cytoplasmic domains of Slit and Netrin receptors specify attraction versus repulsion. | Biological sciences | Greg J. Bashaw, Corey S. Goodman | |||
| Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy.(Statistical Data Included) | Biological sciences | ||||
| CLIP-170 highlights growing microtubule ends in vivo. | Biological sciences | Thomas E. Kreis, Franck Perez, Georgios S. Diamantopoulos, Romaine Stalder | |||
| CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice.(Statistical Data Included) | Biological sciences | Bechara Kachar, Robert A. Lazzarini, Gow Alexander, Cherie M. Southwood, Jing Song Li, Milena Pariali, Gavin P. Riordan, Scott E. Brodie, John Danias, Jeff M. Bronstein | |||
| Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. | Biological sciences | Nancy Kleckner, Yuval Blat | |||
| Combinatorial receptor codes for odors. | Biological sciences | Linda B. Buck, Bettina Malnic, Takaaki Sato, Junzo Hirono | |||
| Control of organ asymmetry in flowers of Antirrhinum.(Statistical Data Included) | Biological sciences | Jennifer Clark, Rosemary Carpenter, Enrico Coen, Da Luo, Coral Vincent, Lucy Copsey | |||
| Cosuppression of nonhomologous transgenes in Drosophila involves mutually related endogenous sequences.(Statistical Data Included) | Biological sciences | James A. Birchler, Manika Pal-Bhadra, Utpal Bhadra | |||
| Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors. | Biological sciences | Mylene Amherdt, Mariella Ravazzola, Thomas H. Sollner, James E. Rothman, Walter Nickel, Martina Bremser, Michael Schweikert, Christine A. Hughes, Felix T. Wieland | |||
| Crossroads on cytoskeletal highways.(Statistical Data Included) | Biological sciences | Elaine Fuchs, Yanmin Yang | |||
| Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p. | Biological sciences | James H. Hurley, Saurav Misra | |||
| Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism. | Biological sciences | William S. Somers, Jin Tang, Jasbir Seehra, James D. Clark, Andrea Dessen, Holly Schmidt, Mark Stahl | |||
| Crystal structure of the cytoplasmic domain of the type I TGFbeta receptor in complex with FKBP12. | Biological sciences | Joan Massague, Ye-Guang Chen, John Kuriyan, Morgan Huse | |||
| Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7.(Statistical Data Included) | Biological sciences | Tom Ellenberger, Charles C. Richardson, Michel R. Sawaya, Shenyuan Guo, Stanley Tabor | |||
| Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface. | Biological sciences | Thorsten Hage, Walter Sebald, Peter Reinemer | |||
| Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.(Statistical Data Included) | Biological sciences | Nikola P. Pavletich, Yigong Shi, Jack E. Dixon, Jie-Oh Lee, Antonio Di Cristofano, Haijuan Yang, Maria-Magdalena Georgescu, Tomohiko Maehama, Pier Pandolfi | |||
| Crystal structure of Thermus aquaticus core RNA polymerase at 3.3-angstrom resolution.(Statistical Data Included) | Biological sciences | Konstantin Severinov, Elizabeth A. Campbell, Seth A. Darst, Gongyi Zhang, Leonid Minakhin, Catherine Richter | |||
| Crystal structure of the tandem phosphatase domains of RPTP LAR.(receptor-like protein tyrosine phosphatases; leukocyte antigen-related proteins) | Biological sciences | Haruo Saito, Florence Poy, Christin A. Frederick, Neil X. Krueger, Hyun-Joo Nam | |||
| Crystal structure of the vinculin tail suggests a pathway for activation.(Statistical Data Included) | Biological sciences | Robert C. Liddington, David R. Critchley, Clive R. Bagshaw, Constantina Bakolitsa, Jose M.de Pereda | |||
| Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism. | Biological sciences | Dale B. Wigley, Mark S. Dillingham, Hosahalli S. Subramanya, Sameer S. Velankar, Panos Soultanas | |||
| Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.(small nuclear ribonucleo-protein particles) | Biological sciences | Reinhard Luhrmann, Robert G. Young, Kiyoshi Nagai, Christian Kambach, Stefan Walke, Johanna M. Avis, Eric de la Fortelle, Veronica A. Raker, Jade Li | |||
| Cycling vrille expression is required for a functional Drosophila clock.(Statistical Data Included) | Biological sciences | Michael W. Young, Justin Blau | |||
| Cystic fibrosis and the salt controversy. | Biological sciences | William B. Guggino | |||
| Cytonemes: cellular processes that project to the principal signalling center in Drosophila imaginal discs. | Biological sciences | Felipe-Andres Ramirez-Weber, Thomas B. Kornberg | |||
| Deconstructing type 2 diabetes. | Biological sciences | Simeon I. Taylor | |||
| Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity. | Biological sciences | Hugo J. Bellen, Kyung-Ok Cho, Shayan Izaddoost, Kwang-Wook Choi, Manzoor A. Bhat, Yue Lu | |||
| Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified Hedgehog from signaling cells. | Biological sciences | Konrad Basler, Barry J. Dickson, Ernst Hafen, Denise Nellen, Richard Burke, Manolo Bellotto, Kirsten-Andre Senti | |||
| Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy. | Biological sciences | Robert M. Weiss, Joseph A. Hill, Kevin P. Campbell, Dimple Bansal, Rita Barresi, Steven A. Moore, Ronald D. Cohn, Volker Straub, Roger Williamson, Ramon Coral-Vasquez, Robin L. Davisson, Ron F. Hrstka | |||
| Dissecting the mechanisms of posttranscriptional gene silencing: divide and conquer. | Biological sciences | Sarah R. Grant | |||
| Distinct mechanisms promote polarity establishment in carpels of Arabidopsis.(Statistical Data Included) | Biological sciences | Yuval Eshed, John L. Bowman, Stuart F. Baum | |||
| Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes. | Biological sciences | Eric S. Lander, Andrius Kazlauskas, Douglas Fambrough, Kimberly McClure | |||
| DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.(Statistical Data Included) | Biological sciences | En Li, Daniel Haber, Daphne W. Bell, Masaki Okano | |||
| Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. | Biological sciences | James E. Haber, Allyson M. Holmes | |||
| Drosophila myc regulates cellular growth during development.(Statistical Data Included) | Biological sciences | David A. Prober, Bruce A. Edgar, Robert N. Eisenman, Peter Gallant, Laura A. Johnston | |||
| Dystroglycan versatility. | Biological sciences | Martin E. Hemler | |||
| EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. | Biological sciences | Philippe Soriano, Eric C. Beattie, William C. Mobley, Frances M. Brodsky, Shu-Hui Liu, Andrew Wilde, Lawrence Lem, David A. Riethof | |||
| Electron Avenue: pathways of disulfide bond formation and isomerization.(Statistical Data Included) | Biological sciences | Jon Beckwith, Laurent Debarbieux | |||
| Electron crystal structure of an RNA polymerase II transcription elongation complex.(Statistical Data Included) | Biological sciences | Roger D. Kornberg, Grant J. Jensen, Claudia L. Poglitsch, Gavin D. Meredith, Anerall L. Gnatt, Wei-hau Chang, Jianhua Fu | |||
| Endomembrane trafficking of Ras: the CAAX motif targets proteins to the ER and Golgi. | Biological sciences | Vi K. Chiu, Mark R. Philips, Edwin Choy, David Michaelson, Takashi Morimoto, Joseph Silletti, Marianna Feoktistov, Ivan E. Ivanov | |||
| Engrailed and hedgehog make the range of wingless asymmetric in Drosophila embryos. | Biological sciences | Cyrille Alexandre, Jean-Paul Vincent, Benedicte Sanson, Nora Fascetti | |||
| Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin. | Biological sciences | Ronald L. Davis, Richard L. Kelley, Mitzi I. Kuroda, Gregg Roman, Victoria H. Meller, Polina R. Gordadze | |||
| Essential role of phosphinositide metabolism in synaptic vesicle recycling.(Statistical Data Included) | Biological sciences | Richard A. Flavell, Pietro De Camilli, Markus R. Wenk, Kohji Takei, Gilbert Di Paolo, Yasuo Nemoto, Ottavio Cremona, Warren T. Kim, Laurie Daniell, Stephen B. Shears, David A. McCromick, Anita Luthi | |||
| Evolving ideas about cyclins. | Biological sciences | James M. Roberts | |||
| Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. | Biological sciences | Anna Shevchenko, Danesh Moazed, Andrej Shevchenko, Wenying Shou, Jae Hong Seol, Christopher Baskerville, W. Susan Chen, Joanne Jang, Harry Charbonneau, Raymond J. Dechaies | |||
| Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-XL induction. | Biological sciences | Carlo Brugnara, Harvey F. Lodish, Stream Wang, Merav Socolovsky, Amy E.J. Fallon | |||
| Finding a partner in a crowd: neuronal diversity and synaptogenesis. | Biological sciences | Tito Serafini | |||
| Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. | Biological sciences | Masatoshi Takeichi, Robert W. Burgess, Thomas L. Schwarz, Tadashi Uemura, Shinji Hirano, Tadao Usui, Yasuyuki Shima, Yuko Shimada | |||
| Flipping the switch to an active spliceosome. | Biological sciences | Heather L. Murray, Kevin A. Jarrell | |||
| For better or worse? Telomerase inhibition and cancer. | Biological sciences | Tyler Jacks, Tita de Lange | |||
| From computer simulations to human disease: emerging themes in protein folding. | Biological sciences | Sheena E. Radford | |||
| From TCR engagement to T cell activation: a kinetic view of T cell behavior.(T cell receptor) | Biological sciences | Antonio Lanzavecchia, Giandomenica Iezzi, Antonella Viola | |||
| Functional association of Nmi with Stat5 and Stat1 in IL-2 and IFNgamma-mediated signaling.(interleukin 2; interferon) | Biological sciences | Susan John, Warren J. Leonard, Ming-Hua Zhu, Maria Berg | |||
| Fundmentally different logic of gene regulation in eukaryotes and prokaryotes. | Biological sciences | Kevin Struhl | |||
| G(beta gamma)-mediated regulation of Golgi organization is through the direct activation of protein kinase D. | Biological sciences | Vivek Malhotra, D. John Faulkner, Colin Jamora, Norma Yamanouye, Johan Van Lint, John Laudenslager, Jackie R. Vendenheede | |||
| Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT. | Biological sciences | Gerald R. Crabtree | |||
| Gene silencing: repeats that count. | Biological sciences | Eric U. Selker | |||
| Germ cells.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Chris Wylie | |||
| Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes. | Biological sciences | John McCarthy, Daniel L. Kastner, Anna-Maija Teppo, Richard J. Powell, Christopher I. Amos, Annamari Ranki, John Mulley, John J. O'Shea, Meredith Wilson, Sheldon M. Cooper, Michael F. McDermott, Kathleen A. Quane, Elizabeth M. McDermott, Ying Wan, Michael G. Molloy, Graham A. Hitman, Ivona Akesentijevich, Jerome Galona, Elizabeth Mansfield, Massimo Gadina, Leena Karenko, Tom Pettersson, David M. Frucht, Martin Aringer, Yelizabeta Torosyan, H. Mehmet Karaarslan, Ian Todd, Geryl Wood, Ryan Schlimgen, Thisum R. Kumarajeewa, John P. Vella | |||
| Giant eyes in Xenopus laevis by overexpression of XOptx2. | Biological sciences | William A. Harris, Anna Philpott, Michael E. Zuber, Muriel Perron, Anne Bang | |||
| gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle. | Biological sciences | Gerald M. Rubin, Naoto Ito | |||
| Global transcription regulators of eukaryotes. | Biological sciences | Genevieve Almouzni, Irwin Davidson, Kerstin Weiss, Stefan Bjorklund, Karl P. Nightingale | |||
| Golgi membranes are absorbed into and reemerge from the ER during mitosis.(Statistical Data Included) | Biological sciences | Robert D. Phair, Jennifer Lippincott-Schwartz, Jan Ellenberg, Nelson B. Cole, Koret Hirschberg, Kristien J.M. Zaal, Carolyn L. Smith, Roman S. Polishchuk, Nihal Altan, John E. Presley, Theresa H Roberts, Eric Siggia | |||
| GroEL-GroES cycling: ATP and nonnative polypeptide direct alternation of folding-active rings. | Biological sciences | Krystyna Furtak, Helen R. Saibil, Arthur L. Horwich, Wayne A. Fenton, Alan M. Roseman, Hays S. Rye, Sahoxia Chen | |||
| Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of cubitus interruptus. | Biological sciences | Konrad Basler, Nathalie Methot | |||
| Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome.(Statistical Data Included) | Biological sciences | Annie Yang, Frank McKeon, Daniel A. Haber, Han G. Brunner, Gert Vriend, Ben C.J. Hamel, Arie P.T. Smits, Raoul C.M. Hennekam, Hans van Bokhoven, Michael Bamshad, Arie van Haeringen, Jacopo Celli, Pascal Duijf, Bridget Kramer, Ruth Newbury-Ecob, Griet Van Buggenhout, Rob de Waal | |||
| High-resolution model of the microtubule. | Biological sciences | Eva Nogales, Ronald A. Milligan, Kenneth H. Downing, Michael Whittaker | |||
| Histone octamer transfer by a chromatin-remodeling complex. | Biological sciences | Roger D. Kornberg, Yahli Lorch, Mincheng Zhang | |||
| HIV-1 entry inhibitors in the side pocket.(Statistical Data Included) | Biological sciences | Joseph G. Sodroski | |||
| How do antidepressants work? Prospects for genetic analysis of drug mechanisms. | Biological sciences | William R. Schafer | |||
| How the cyclin became a cyclin: regulated proteolysis in the cell cycle. | Biological sciences | Stephen J. Elledge, J. Wade Harper, Deanna M. Koepp | |||
| Identification and cloning of a negative regulator of systemic acquired resistance, SNI1, through a screen for suppressors of npr1-1. | Biological sciences | Yan Li, Xinnian Dong, Joseph D. Clarke, Xin Li Zhang | |||
| Identification of a neural stem cell in the adult mammalian central nervous system. | Biological sciences | Diana L. Clarke, Jonas Frisen, Clas B. Johansson, Urban Lendahl, Stefan Momma, Marten Risling | |||
| Identification of cohesin association sites at centromeres and along chromosome arms.(Statistical Data Included) | Biological sciences | Kim Nasmyth, Maria Pia Cosma, Tomoyuki Tanaka, Karin Wirth | |||
| Increasing the complexity of coactivation in nuclear receptor signaling. | Biological sciences | Leonard P. Freedman | |||
| Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.(c-Jun N-terminal kinase/stress-activated protein kinase) | Biological sciences | Jonathan D. Oliner, Leif W. Ellisen, Christoph Englert, James M. Bean, Shyamala Maheswaran, D. Paul Harkin, David Miklos, Young-Han Song, Vivi B. Truong, Fred C. Christians, Daniel A Haber | |||
| Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. | Biological sciences | Jin Wang, Stephen E. Straus, Michael J. Lenardo, Jennifer M. Puck, Lixin Zheng, Adrian Lobito, Francis Ka-Ming, Janet Dale, Michael Sneller, Xu Yao | |||
| Inheriting the golgi. | Biological sciences | Michael G. Roth | |||
| Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket.(Statistical Data Included) | Biological sciences | Peter S. Kim, Debra M. Eckert, Vladimir N. Malashkevich, Lily H. Hong, Peter A. Carr | |||
| Inhibition of SNARE complex assembly differentially affects kinetic components of exocytosis. | Biological sciences | Erwin Neher, Reinhard Jahn, Tao Xu, Burkhard Rammner, Martin Margittai, Antonio R. Artalejo | |||
| In response to Fakruddin et al. and Apostolou et al.(in this issue) | Biological sciences | Peter G. Isaacson, Milena Gasco, Tony G. Willis, Dalal M. Jadayel, Ming-Qing Du, Huaizheng Peng, Amanda R. Perry, Martin J.S. Dyer, Helen P. Price, Rifat A. Hamoudi | |||
| Insights into the function of rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice. | Biological sciences | Gabriel H. Travis, David G. Birch, Jian Weng, Nathan L. Mata, Sassan M. Azarian, Radouil T. Tzekov | |||
| Integrators of the cytoskeleton that stabilize microtubules. | Biological sciences | Elaine Fuchs, Christoph Bauer, Jean-Pierre Julien, Robert Wollman, Yang Yanmin, Geraldine Strasser | |||
| Intercellular connections are developmentally controlled to help move molecules through the plant. | Biological sciences | Barbara G. Pickard, Roger N. Beachy | |||
| Involvement of caspases in proteolytic cleavage of ALzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. | Biological sciences | Hui Zheng, Donald W. Nicholson, David Smith, Sophie Roy, Andrea LeBlanc, John P. Vaillancourt, Nancy A. Thornberry, Francois G. Gervais, Gaigen Xu, George S. Robertson, Yanxia Zhu, jingQi Huang, Michael Rigby, Shearman. Mark S., Earl E. Clarke, Leonardus H.T. Van Der Ploeg, Salvatore C. Ruffolo, Steve Xanthoudakis, Robert J. Zamboni | |||
| It's spring, and thoughts turn to ... allergies. | Biological sciences | Christopher M. Dobson, Henry Metzger | |||
| KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness. | Biological sciences | Bjorn C. Schroeder, Thomas J. Jentsch, Thomas Friedrich, Christine Petit, Sandrine Marlin, Christian Kubisch, Bjorn Lutjohann, Aziz El-Amraoui | |||
| Kin I kinesins are microtubule-destabilizing enzymes. | Biological sciences | Timothy J. Mitchison, Claire E. Walczak, Arshad Deasi, Suzie Verma | |||
| "Kissin' cousins": intimate plasma membrane - ER interactions underlie capacitative calcium entry.(endoplasmic reticulum) | Biological sciences | James W. Putney Jr. | |||
| Lack of BCL10 mutations in germ cell tumors and B cell lymphomas. | Biological sciences | V.V.V.S. Murty, R.S.K. Chaganti, J. Mohamed Fakruddin | |||
| Last but not least: regulated poly(A) tail formation. | Biological sciences | Walter Keller, Silvia M.L. Barabino | |||
| Lateral signaling mediated by axon contact and calcium entry regulates asymmetric odorant receptor expression in C. elegans.(Statistical Data Included) | Biological sciences | ||||
| Lipoprotein receptors: signaling functions in the brain? | Biological sciences | Jonathan A. Cooper, Brian W. Howell | |||
| Longevity, stress response, and cancer in aging telomerase-deficient mice. | Biological sciences | Han-Woong Lee, Ronald A. DePinho, Sandy Chang, Geoffrey J. Gottlieb, Karl Lenhard Rudolph, Maria Blasco, Carol Greider | |||
| Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. | Biological sciences | Kenneth R. Chien, Klaus Rajewsky, Yusu Gu, John Ross Jr., Werner Muller, Hisao Hirota, Ju Chen, Ulrich A.K. Betz | |||
| Mammalian fertilization: molecular aspects of gamete adhesion, exocytosis, and fusion.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Paul M. Wassarman | |||
| Mammalian telomeres end in a large duplex loop. | Biological sciences | Titia de Lange, Jack D. Griffith, Laurey Comeau, Soraya Rosenfield, Rachel M. Stansel, Alessandro Biachi, Heidi Moss | |||
| MCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop.(mouse cryptochrome genes) | Biological sciences | Lauren P. Shearman, Steven M. Reppert, Mark J. Zylka, David R. Weaver, Kazuhiko Kume, Sathyanarayanan Sriram, Michael H. Hastings | |||
| Measles virus infection in a transgenic model: virus-induced immunosuppression and central nervous system disease. | Biological sciences | Michael B.A. Oldstone, Dirk Homann, Hanna Lewicki, Diane Thomas, Antoinette Tishon, Samuel Dales, John Patterson, Mari Manchester, Denise Naniche, Andreas Holz | |||
| MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. | Biological sciences | Leonard Guarente, David A. Sinclair, Kevin D. Mills | |||
| Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. | Biological sciences | Bruce M. Spiegelman, Pere Puigserver, Zhidan Wu, Guillaume Adelmant, Richard C. Scarpulla, Saverio Cinti, Vamsi Mootha, Bradford Lowell, Ulf Anderson, Chenyu Zhang, Amy Troy | |||
| Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription.(activator protein 1) | Biological sciences | Stephen J. Marx, Settara C. Chandrasekharappa, Francis Collins, Allen M. Spiegel, Michael R. Erdos, Sunita K. Agarwal, Siradanahalli C. Guru, Christina Heppner, Regina M. Collins, Sylvia Y. Park, Suraj Saggar, A. Lee Burns | |||
| Mesenchymal to epithelial conversion in rat metanephros is induced by LIF.(leukemia inhibitory factor)(Statistical Data Included) | Biological sciences | Juan A. Oliver, Hediye Erdjument-Bromage, Paul Tempst, Jun Yang, Jonathan Barasch, Kanji Yoshida, Elvira Parravicini, Tetsuya Taga, Carol B. Ware, Stephen Malach, Tsvi Aranoff | |||
| Methylation-induced repression: belts, braces and chromatin.(Statistical Data Included) | Biological sciences | Alan P. Wolffe, Adrian P. Bird | |||
| Mice with reduced NMDA receptor expression display behaviors related to schizophrenia.(N-methyl-D-aspartate) | Biological sciences | Raul R. Gainetdinov, Marc G. Caron, Beverly H. Koller, Amy R. Mohn | |||
| MIG-13 positions migrating cells along the anteroposterior body axis of C. elegans. | Biological sciences | Cynthia Kenyon, Mary Sym, Naomi Robinson | |||
| MiRP1 forms I(sub kr) potassium channels with HERG and is associated with cardiac arrhythmia.(MinK-related peptide 1, pore-forming protein) | Biological sciences | Mark T. Keating, Federico Sesti, Steve A.N. Goldstein, Geoffrey W. Abbott, Michael H. Lehmann, Katherine W. Timothy, Igor Splawski, Marianne E. Buck | |||
| Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission. | Biological sciences | Jon Storm-Mathisen, Richard J. Reimer, Robert H. Edwards, Farrukh A. Chaudhry, David Krizaj, Diane Barber, David R. Copenhagen | |||
| Molecular bases for circadian clocks.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Jay C. Dunlap | |||
| Molecular biology of aging.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Leonard Guarente, David A. Sinclair, F. Brad Johnson | |||
| Molecular development of sensory maps: representing sights and smells in the brain.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Paul A. Yates, Todd McLaughlin, Dennis D.J. O'Leary | |||
| Molecular interactions continuously define the organizer during the cell movements of gastrulation. | Biological sciences | Claudio D. Stern, Katherine Joubin | |||
| Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model. | Biological sciences | Frederick M. Ausubel, Man-Wah Tan, Shalina Mahajan-Miklos, Laurence G. Rahme | |||
| Morphogenesis.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Brigid L.M. Hogan | |||
| MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover.(Statistical Data Included) | Biological sciences | Jerrold M. Ward, Henning Birkedal-Hansen, Kenn Holmbeck, Paolo Bianco, Pamela Gehron Robey, A. Robin Poole, John Caterina, Susan Yamada, Mark Kromer, Sergei A. Kuznetsov, Mahesh Mankani, Isabelle Pidoux | |||
| mut-7 of C. elegans, required for transposon silencing and RNA interference is a homolog of Werner syndrome helicase and RNaseD.(Statistical Data Included) | Biological sciences | Rene F. Ketting, Ronald H.A. Plasterk, Thomas H.A. Haverkamp, Henri G.A.M.van Luenen | |||
| Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. | Biological sciences | John B. Lowe, David Ginsburg, Peter L. Smith, Karen L. Mohlke, Anjali A. Purkayastha, Randal J. Westrick, Bronia Petryniak | |||
| Narcolepsy: a key role for hypocretins (orexins). | Biological sciences | Jerome M. Siegel | |||
| Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. | Biological sciences | James A. Richardson, Robert E. Hammer, Masashi Yanagisawa, Joel K. Elmquist, Clifford B. Saper, Richard M. Chemelli, S. Clay Williams, Jon T. Willie, Christopher M. Sinton, Thomas Scammell, Charlotte Lee, Yumei Xiong, Yaz Kisanuki, Thomas E. Fitch, Masamitsu Nakazato | |||
| Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes. | Biological sciences | Didier Trono, Feng Gu, Vincent Piguet, Nicolas Demaurex, Michelangelo Foti | |||
| Negative feedback mechanisms and their roles during pattern formation. | Biological sciences | Andrew P. McMahon, Norbert Perrimon | |||
| NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. | Biological sciences | Yuki Yamaguchi, Tadashi Wada, Hiroshi Handa, Toshiyuki Takagi, Jun Hasegawa, Seiji Sugimoto, Keiichi Yano, Akiko Furuya | |||
| Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. | Biological sciences | Raymond J. Deshaies, Alexander D. Johnson, Danesh Moazed, Wenying Shou, Aaron F. Straight, Gustave J. Dowd, Christoph W. Turck | |||
| Net results of nucleolar dynamics. | Biological sciences | Lorraine Pillus, Sandra N. Garcia | |||
| New insights into the interaction of Ras with the plasma membrane. | Biological sciences | Chris Marshall, Tony Magoo | |||
| Nitric oxide contributes to behavioral, cellular, and developmental responses to low oxygen in Drosophila. | Biological sciences | Patrick H. O'Farrell, James A. Wingrove | |||
| Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. | Biological sciences | Roseanne M. Hofmann, Cecile M. Pickart | |||
| Novel DNA polymerases offer clues to the molecular basis of mutagenesis. | Biological sciences | Errol C. Friedburg, Valerie L. Gerlach | |||
| Novel functions of nanos in downregulating mitosis and transcription during the development of the Drosophila germline.(Statistical Data Included) | Biological sciences | Girish Deshpande, Gretchen Calhoun, Judith L. Yanowitz, Paul D. Schedl | |||
| Nuclear orphan receptors control cholesterol catabolism. | Biological sciences | David W. Russell | |||
| Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade.(MAP kinase) | Biological sciences | Sanjoy K. Mahanty, Yunmei Wang, Francis W. Farley, Elaine A. Elion | |||
| Nuclear trafficking of cubitus interruptus in the transcriptional regulation of hedgehog target gene expression. | Biological sciences | Baolin Wang, Philip A. Beachy, Chien-Huan Chen, Yong Ma, Doris P. von Kessler, Woojin Park | |||
| Nucleosome movement by CHRAC and ISWI without disruption or trans-displacement of the histone octamer.(chromatin accessibility complex) | Biological sciences | Peter B. Becker, Gernot Langst, Edgar J. Bonte, Davide F.V. Corona | |||
| Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13. | Biological sciences | Marino Zerial, Angelika Giner, Carol Murphy, Heidi McBride, Valdimir Rybin, Rohan Teasdale | |||
| Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle - and developmentally regulated promoter. | Biological sciences | Kim Nasmyth, Maria Pia Cosma, Tomoyuki Tanaka | |||
| Oxidative protein folding is driven by the electron transport system. | Biological sciences | James C.A. Bardwell, Wilson Muse, Martin Bader, David P. Ballou, Christian Gassner | |||
| Oxygen regulation of airway branching in Drosophila is mediated by Branchless FGF.(Statistical Data Included) | Biological sciences | Mark A. Krasnow, Eric Johnson, Jill Jarecki | |||
| p27(super.Xic1), a Cdk inhibitor, promotes the determination of glial cells in Xenopus retina.(Statistical Data Included) | Biological sciences | Kevin Wang, Christine E. Holt, William A. Harris, Anna Philpott, Shin-ichi Ohnuma | |||
| p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. | Biological sciences | Carol W. Greider, Ronald A. DePinho, Steven E. Artandi, Lynda Chin, Qiong Shen, Tam. Alice, Shwu-Luan Lee, Geoffrey J. Gottieb | |||
| Pak functions downstream of dock to regulate photoreceptor axon guidance in Drosophila.(p21-activated kinase) | Biological sciences | S. Lawrence Zipursky, Louis Lim, Huey Hing, Jian Xiao, Nicholas Harden | |||
| Pch2 links chromatin silencing to meiotic checkpoint control. | Biological sciences | G. Shirleen Roeder, Pedro A. San-Segundo | |||
| Perspectives on oxygen sensing. | Biological sciences | Gregg L. Semenza | |||
| Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation.(Statistical Data Included) | Biological sciences | Hiroshi Watanabe, Hiroshi Nakamura, Andrew J. Morris, Michael A. Frohman, Masakazu Yamazaki, Masahiro Nogami, Akira Honda, Takeaki Yokozeki, Kazumasa Kawamoto, Kazuhisa Nakayama, Yasunori Kanaho | |||
| Phosphoinositide binding domains: embracing 3-phosphate. | Biological sciences | Lewis C. Cantley, David A. Fruman, Rameh. Lucia E. | |||
| Phosphorylation of histone H3 is required for proper chromosome condensation and segregation. | Biological sciences | C. David Allis, Yi Wei, Martin A. Gorovsky, Lanlan Yu, Josephine Bowen | |||
| Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.(Statistical Data Included) | Biological sciences | Fumio Nakamura, Stephen M. Strittmatter, Takuya Takahashi, Hajime Fujisawa, Alyson Fournier, Li-Hsien Wang, Yasunori Murakami, Robert G. Kalb | |||
| Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.(Statistical Data Included) | Biological sciences | Marc Tessier-Lavigne, Mu-ming Poo, Corey S. Goodman, Hang Chen, Alain Chedotal, Paolo M. Comoglio, Zhigang He, Hong-jun Song, Guo-li Ming, Luca Tamagnone, Margaret L. Winberg, Stefania Artigiani | |||
| Polypeptide flux through bacterial Hsp70: DnaK cooperates with trigger factor in chaperoning nascent chains. | Biological sciences | Gunter Fischer, F. Ulrich Hartl, Costa Georgopoulos, Paul Blum, Walid A. Houry, Sarah A. Teter, Debbie Ang, Thomas Tradler, David Rockabrand | |||
| PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs.(Statistical Data Included) | Biological sciences | Kenneth W. Kinzler, Bert Vogelstein, Timothy A. Chan, Tong-Chuan He | |||
| PPAR-gamma: an essential regulator of adipogenesis and modulator of fat cell function.(peroxisome proliferator-activated receptor-gamma)(Statistical Data Included) | Biological sciences | Bradford B. Lowell | |||
| Prion protein of 106 residues creates an artificial transmission barrier for prion replication in transgenic mice. | Biological sciences | Stanley B. Prusiner, Michael Scott, Stephen J. DeArmond, Fred E. Cohen, Marilyn Torchia, Surachai Suppaattapone, Patrick Bosque, tamaki Muramoto, Holger Wille, Claus Aagaard, David Peretz, Hoang-Oanh B. Nguyen, Cornelia Heinrich, Jiri Safar | |||
| Progression from extrinsic to intrinsic signaling in cell fate specification: a view from the nervous system.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Thomas M. Jessell, Thomas Edlund | |||
| Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells. | Biological sciences | David J. Anderson, Sean J. Morrison, Patricia M. White, Christiane Zock | |||
| Proteins of the CNR family are multiple receptors for Reelin.(Statistical Data Included) | Biological sciences | Takeshi Yagi, Masaharu Ogawa, Kouji Senzaki | |||
| Protein translocation: how Hsp70 pulls it off.(heat shock 70 protein) | Biological sciences | Randy Schekman, Marinus Pilon | |||
| Prox1 (ital) function is required for the development of the murine lymphatic system.(Statistical Data Included) | Biological sciences | Guillermo Oliver, Jeffrey T. Wigle | |||
| Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity.(G-protein coupled receptors) | Biological sciences | Elliot Adler, Mark A. Hoon, Nicholas J.P. Ryba, Charles S. Zuker, Jurgen Lindemeier, James F. Battey | |||
| Putting boundaries on silence.(Statistical Data Included) | Biological sciences | Sarah C.R. Elgin, Fang-Lin Sun | |||
| RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides.(receptor for advanced glycation end) | Biological sciences | John Morser, Ann Marie Schmidt, David Stern, Cecilia Avila, Angelika Bierhaus, Markus F. Neurath, Peter Nawroth, Neeraja Kambham, Timothy Slattery, Mariko Nagashima, Marion A. Hofmann, Steven Drury, Caifeng Fu, Wu Qu, Akihiko Taguchi, Yan Lu, Dale Beach, John McClary | |||
| Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. | Biological sciences | Michael G. Rosenfeld, Aneel K. Aggarwal, Mathias Treier, Daniel P. Szeto, Farideh Hooshmand, Shawn M. O'Connell, Sarah E. Flynn, Anatoli S. Gleiberman, Jeremy SS. Dasen | |||
| Recognition of a TG Mismatch: the crystal structure of very short patch repair endonuclease in complex with a DNA duplex.(Statistical Data Included) | Biological sciences | Kosuke Morikawa, Susan E. Tsutakawa, Hisato Jingami | |||
| Recognition of polyadenylate RNA by the poly(A)-binding protein.(Statistical Data Included) | Biological sciences | Stephen K. Burley, Nahum Sonenberg, Rahul C. Deo, Jeffrey B. Bonanno | |||
| Reeler/disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.(very low density lipoprotein; apolipoprotein E) | Biological sciences | James A. Richardson, Robert E. Hammer, John Shelton, Joachim Herz, Marion Trommsdorff, Michael Gotthardt, Thomas Hiesberger, Walter Stockinger, Johannes Nimpf | |||
| Regulation and temporal expression patterns of Vibrio cholerae virulence genes during infection.(Statistical Data Included) | Biological sciences | Matthew K. Waldor, Sang Ho Lee, David L. Hava, Andrew Camilli | |||
| Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation.(Discs large) | Biological sciences | Leslie C. Griffith, Ulrich Thomas, Young Ho Koh, Evgenya Popova, Vivian Budnik | |||
| Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A.(p300/CBP-associated factor) | Biological sciences | Pier Lorenzo Puri, Jean Y.J. Wang, Yoshihiro Nakatani, Vasily Ogryzko, Vittorio Sartorelli, Larry Kedes, Yasuo Hamamori, Hung-Yi Wu | |||
| Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. | Biological sciences | ||||
| Regulation of membrane trafficking: structural insights from a Rab/effector complex. | Biological sciences | Richard H. Scheller, Lino Gonzalez Jr. | |||
| Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast.(silent information regulator) | Biological sciences | Susan M. Gasser, Noriyuki Suka, Thierry Laroche, Sophie G. Martin, Michaael Grunstein | |||
| Reorganizing the organizer 75 years on.(the gastrula organizer) | Biological sciences | M. Angela Nieto | |||
| Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin.(proliferating cell nuclear antigen; chromatin assembly factor 1) | Biological sciences | Bruce Stillman, Kei-ichi Shibahara | |||
| Repression: targeting the heart of the matter.(Statistical Data Included) | Biological sciences | Danny Reinberg, Michael Hampsey, Edio Maldonado | |||
| Rescue of cyclin D1 deficiency by knockin cyclin E. | Biological sciences | Robert A. Weinberg, Rene H. Medema, Roderick T. Bronson, Piotr Sicinski, Yan Geng, Tiansen Li, Mary Y. Park, Wendy Whoriskey | |||
| RESPONSIVE-TO-ANTAGONISt1, a Menkes/Wilson disease-related copper transporter, is required for ethylene signaling in Arabidopsis. | Biological sciences | Jose M. Alonso, Joseph R. Ecker, Andrew Dancis, Joseph J. Kieber, William P. Dailey, Takashi Hirayama, Noriko Hirayama, Mikhail Kogan, Pinio Guzman, Saeid Nourizadeh | |||
| Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1. | Biological sciences | Andrew W. Tai, Jen-Zen Chuang, Christian Bode, Uwe Wolfrum, Ching-Hwa Sung | |||
| Ribosomal mechanics, antibiotics, and GTP hydrolysis. | Biological sciences | Roger A. Garrett, Bo. T. Porse | |||
| RNA polymerase unveiled. | Biological sciences | Robert Landick, Rachel Anne Mooney | |||
| Selector genes and limb identity on arthropods and vertebrates. | Biological sciences | Sean B. Carroll, Scott D. Weatherbee | |||
| Short dysfunctional telomeres impair tumorigenesis in the INK4aDelta2/3 cancer-prone mouse. | Biological sciences | Carol W. Greider, Ronald A. DePinho, Lynda Chin, Robert H. Singer, Roger A. Greenberg, Geoffrey J. Gottlieb, Andrea Femino, Kee-Ho Lee | |||
| Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice.(Statistical Data Included) | Biological sciences | ||||
| Signaling networks - do all roads lead to the same genes? | Biological sciences | Tony Pawson, Tracy M. Saxton | |||
| Signal-regulated activation of serum response factor is mediated by changes in actin dynamics. | Biological sciences | Richard Treisman, John Copeland, Athanassia Sotiropoulos, Dziugas Gineitis | |||
| Simple, but not branched, plasmodesmata allow the nonspecific trafficking of proteins in developing tobacco leaves. | Biological sciences | Ian Roberts, Karl J. Oparka, Alison G. Roberts, Petra Boevink, Simon Santa Cruz, Katja S. Pradel, Astrid Imlau, Guy Kotlizky, Norbert Sauer, Bernard Epel | |||
| Sin meets NuRD and other tails of repression.(Statistical Data Included) | Biological sciences | Robert N. Eisenman, Paul S. Knoepfler | |||
| Sir-Ku-itous routes to make ends meet.(Ku and Sir proteins at telomeres) | Biological sciences | James E. Haber | |||
| Size control in animal development.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Martin Raff, Ian Conion | |||
| Slit branches out: a secreted protein mediates both attractive and repulsive axon guidance. | Biological sciences | Kai Zinn, Qi Sun | |||
| Slit is the midline repellent for the Robo receptor in Drosophila.(Roundabout) | Biological sciences | Thomas Kidd, Corey S. Goodman, Kimberley S. Bland | |||
| Slit proteins bind Robo receptors and have an evolutionary conserved role in repulsive axon guidance.(Roundabout) | Biological sciences | Marc Tessier-Lavigne, Thomas Kidd, Corey S. Goodman, Kimberly S. Bland, Katja Brose, David Arnott, William Henzel, Kuan Hong Wang | |||
| Snapshots of ARF1: implications for mechanisms of activation and inactivation.(ADP-ribosylation factor 1) | Biological sciences | Michael G. Roth | |||
| SNARE complex formation is triggered by Ca2+ and drives membrane fusion.(core complex of syntaxin, SNAP-25 and VAMP) | Biological sciences | Richard H. Scheller, Suzie J. Scales, Yu A. Chen, Sejal M. Patel, Yee-Cheen Doung | |||
| SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality.(suppressor of cytokine signaling-1) | Biological sciences | Jean-Christophe Marine, James N. Ihle, Akihiko Yoshimura, Catriona McKay, Dimitrios Stravopodis, Demin Wang, Evan Parganas, David J. Topham | |||
| SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.(suppressor of cytokine signaling-1) | Biological sciences | Donald Metcalf, Robyn Starr, Nicos A. Nicola, Douglas J. Hilton, Warren S. Alexander, Jennifer E. Fenner, Clare L. Scott, Emanuela Handman, Naomi S. Sprigg, Jason E. Corbin, Ann L. Cornish, Rima Darwiche, catherine M. Oczarek, Thomas W.H. Kay, Paul J. Hertzog | |||
| SOCS3 is essential in the regulation of fetal liver erythropoiesis.(suppressor of cytokine signaling-3) | Biological sciences | Jean-Christophe Marine, Atsuo Sasaki, Hideo Yasukawa, Hideaki Nakajima, Helene Pendeville, Catriona McKay, Demin Wang, Evan Parganas, David J. Topham, Akihko Yoshimura, Jame N. Ihle | |||
| Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions.(Statistical Data Included) | Biological sciences | Ad Bax, Paul T. Wingfield, Yves Pommier, Dennis A. Torchia, Stephen J. Stahl, Yun-Xing Wang, Nouri Neamati, Jaison Jacob, Ira Palmer, Joshua D. Kaufman, Philip Lin Huang, Paul Lee Huang, Heather E. Winslow, Sylvia Lee-Huang | |||
| Solution structure of BID, an intracellular amplifier of apoptotic signaling. | Biological sciences | Junying Yuan, Guy S. Salvesen, Gerhard Wagner, James J. Chou, Honglin Li | |||
| Solution structure of the CIDE-N domain of CIDE-B and a model of CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis. | Biological sciences | Gerhard Wagner, Alexey A. Lugovskoy, James J. Chou, Pei Zhou, John S. McCarty, Pendg Li | |||
| Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists. | Biological sciences | Stanley J. Korsmeyer, David Cowburn, David Fushman, James M. McDonnell, Curt L. Milliman | |||
| Spo76p is a conserved chromosome morphogenesis protein that links the mitotic and meiotic programs. | Biological sciences | Denise Zickler, Francoise James, Veronique Berteaux-Lecellier, Diana van Heemst, Stefanie Poggeler | |||
| Sprouty, an intracellular inhibitor of Ras signaling. | Biological sciences | Matthew Freeman, Tanita Casci, Javier Vinos | |||
| Squid hnRNP protein promotes apical cytoplasmic transport and localization of Drosophila pair-rule transcripts. | Biological sciences | Trudi Schupbach, David Ish-Horowicz, Amanda Norvell, Sabbi Lall, Helen Francis-Lang, Antonin Flament | |||
| Stabilization of chromatin structure by PRC1, a polycomb complex. | Biological sciences | Robert E. Kingston, Zhaohui Shao, Welcome Bender, Florian Raible, Chao-ting Wu, Ramin Mollaaghababa, Jeffrey R. Guyon | |||
| Stat3 as an oncogene.(signal transducers and activators of transcription) | Biological sciences | Richard G. Pestell, Yanxiang Zhao, James E. Darnell Jr., Geeta Devgan, Jacqueline F. Bromberg, Melissa H. Wrzeszczynska, Chris Albanese | |||
| Store-operated Ca2+ entry: evidence for a secretion-like coupling model. | Biological sciences | Donald L. Gill, Damian B. van Rossum, Randen L. Patterson | |||
| Stress pathways and heart failure. | Biological sciences | Kenneth R. Chien | |||
| Structural and functional analysis of the ARF1-ARFGAP complex reveals a role for coatomer in GTP hydrolysis. | Biological sciences | Jonathan Goldberg | |||
| Structural basis for FGF receptor dimerization and activation.(fibroblast growth factor) | Biological sciences | Joseph Schlessinger, Stevan R. Hubbard, Moosa Mohammadi, Alexander N. Plotnikov | |||
| Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. | Biological sciences | Richard G. Brennan, Ekaterina E. Zheleznova, Penelope N. Markham, Alexander A. Neyfakh | |||
| Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A. | Biological sciences | Axel T. Brunger, Christian Ostermeier | |||
| Structural insights into the mechanism of intramolecular proteolysis. | Biological sciences | Qian Xu, Deirdre Buckley, Chudi Guan, Hwai-Chen Guo | |||
| Structural view of the Ran-Importin beta interaction at 2.3 A resolution. | Biological sciences | Alfred Wittinghofer, Ingrid R. Vetter, Ulrike Kutay, Dirk Gorlich, Andreas Arndt | |||
| Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.(Statistical Data Included) | Biological sciences | ||||
| Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. | Biological sciences | Gerhard Wagner, Ellis L. Reinherz, Alex Smolyar, Jin-huan Liu, Jia-huai Wang, Kemin Tan, Mikyung Kim, Zhen-yu J. Sun | |||
| Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation. | Biological sciences | Cynthia Wolberger, Michael L. Cleary, Derek E. Piper, Adrian H. Batchelor, Ching-Pin Chang | |||
| Structure of a voltage-dependent K+ channel beta subunit. | Biological sciences | Roderick MacKinnon, Jacqueline M. Gulbis, sabine Mann | |||
| Structure of CheA, a signal-transducing histidine kinase. | Biological sciences | Melvin I. Simon, Brian R. Crane, Lisa A. Alex, Alexandrine M. Bilwes | |||
| Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments. | Biological sciences | Matti Saraste, Mathias Gautel, Paul Young, Kristina Djinovic-Carugo | |||
| Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis. | Biological sciences | David J. Hosfield, Yue Guan, Brian J. Haas, Richard P. Cunnigham, John A. TAiner | |||
| Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of the actin assembly.(vasolidator-stimulated phosphoprotein) | Biological sciences | Wendell A. Lim, Kenneth E. Prehoda, Do J. Lee | |||
| Structures of two repeats of spectrin suggest models of flexibility. | Biological sciences | Alfonso Mondragon, Valerie L. Grum, Dongning Li, Ruby I. MacDonald | |||
| Substrate targeting in the ubiquitin system. | Biological sciences | Mark Hochstrasser, Jeffrey D. Laney | |||
| Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. | Biological sciences | Arturo Alvarez-Buylla, Fiona Doetsch, Isabelle Caille, Daniel A. Lim, Jose Manuel Garcia-Verdugo | |||
| Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.(vascular endothelial growth factor) | Biological sciences | Jean-Marc Herbert, Peter Carmeliet, Florea Lupu, Mieke Dewerchin, Desire Collen, Dieter Nuyens, Veerle Compernolle, Lieve Moons, Francoise Bono, Elizabetta Dejana, Frederic Clotman, Maria-Grazia Lampugnani, Ferrucio Breviario, Giovanna Balconi, Raffaella Spagnuolo, Bert Oosthuyse, Adriana Zanetti, Anne Angellilo, Virginie Mattot, Esther Lutgens, Marco C. de Ruiter, Adriana Gittenberger-de Groot, Rob Poelmann | |||
| Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development.(Statistical Data Included) | Biological sciences | Robin Lovell-Badge, Richard R. Behringer, Nelson A. Arango | |||
| Targeted mutagenesis of Tsix (ital) leads to nonrandom X inactivation.(Statistical Data Included) | Biological sciences | Jeannie T. Lee, Naifang Lu | |||
| Targeting mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development.(Statistical Data Included) | Biological sciences | Robin Lovell-Badge, Richard R. Behringer, Nelson A. Arango | |||
| Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. | Biological sciences | Daniel E. Gottschling, Scott J. Diede | |||
| The 2.8 Angstrom crystal structure of visual arrestin: a model for arrestin's regulation. | Biological sciences | Paul B. Sigler, Vsevolod V. Gurevich, Carsten Schubert, Joel A. Hirsch | |||
| The actin cytoskeleton and lymphocyte activation. | Biological sciences | Josef Penninger, Gerald R. Crabtree | |||
| The crystal structure of a GroEL/peptide complex: plasticity as a basis for substrate diversity. | Biological sciences | Paul B. Sigler, Lingling Chen | |||
| The 'dark side' of chromatin remodeling: repressive effects on transcription.(Statistical Data Included) | Biological sciences | James T. Kadonaga, Jessica K. Tyler | |||
| The DNA double-strand break repair gene hMRE11 is mutated in individuals with an Ataxia-telangiectasia-like disorder.(Statistical Data Included) | Biological sciences | Richard S. Maser, John H.J. Petrini, Grant S. Stewart, Anja Raams, Tanja Stankovic, Debra A. Bressan, Mark I. Kaplan, Nikolaas G.J. Jaspers, Philip J. Byrd, R. Taylor Malcolm | |||
| The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.(Head Involution Defective) | Biological sciences | Soon Ji Yoo, Bruce A. Hay, Susan L. Wang, Christine J. Hawkins, H.-Arno J. Muller | |||
| The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation. | Biological sciences | Christine Rushlow, Nikolai Kirov, Eric Wieschaus, Siegfried Roth, Anna Jazwinska | |||
| The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. | Biological sciences | Alexander F. Schier, William S. Talbot, Jiaojiao Zhang, Kira Gristman, Simon Cheng, Elizabeth Heckscher | |||
| The Ephrin VAB-2/EFN-1 functions in neuronal signaling to regulate epidermal morphogenesis in C. elegans. | Biological sciences | Andrew D. Chisholm, Ian D. Chin-Sang, Sean E. George, Mei Ding, Sarah L. Moseley, Andrew S. Lynch | |||
| The exosome: a proteasome for RNA?(Statistical Data Included) | Biological sciences | Roy Parker, Ambro Van Hoof | |||
| The highly ordered double-stranded RNA genome of bluetongue virus revealed by crystallography. | Biological sciences | Jonathan M. Grimes, David I. Stuart, Jonathan M. Diprose, J. Nicholas Burroughs, Patrice Gouet, Robyn Malby, Stephan Zientara, Peter P. C. Mertens | |||
| The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration.(Statistical Data Included) | Biological sciences | Jeffrey Vieira, Jay A. Nelson, Patricia Smith, Yoram Altschuler, Cecilia Soderberg-Naucler, Daniel N. Streblow, Eiko Wakabayashi, Franziska Ruchti, Mattison Kirsten | |||
| The inositol triphosphate receptor regulates a 50-second behavioral rhythm in C. elegans.(Statistical Data Included) | Biological sciences | Erik M. Jorgensen, Andrew D. Chisholm, Paola Dal Santo, Mary A. Logan | |||
| The integrin alphavbeta6 binds and activates latent TGFbeta1: a mechanism for regulating pulmonary inflammation and fibrosis.(transforming growth factor) | Biological sciences | Michael A. Matthay, Dean Sheppard, Naftali Kaminski, Mark J.D. Griffiths, John S. Munger, Xiaozhu Huang, Hisaaki Kawakatsu, Stephen L. Dalton, Jianfeng Wu, Jean-Francois Pittet, Chrystelle Garat, Daniel B. Rifkin | |||
| The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. | Biological sciences | Tomas Kirchhausen, Marc W. Kirschner, Tadaomi Takenawa, Hiroaki Miki, Marco Lopez, Rajat Rohatgi, Le Ma | |||
| The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins.(Statistical Data Included) | Biological sciences | Michael W. Parker, Arthur E. Johnson, Jamie Rossjohn, Rodney K. Tweten, Oleg Shatusdky, Alejandro P. Heuck, Laura A. Shepard | |||
| The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease. | Biological sciences | Morris Schambelan, Susan Bonner-Weir, Philip Leder, Christoph H. Westphal, Donald F. Steiner, Laurent Muller, An Zhou, Xiaorong Zhu, Iris Lindberg | |||
| The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification.(Statistical Data Included) | Biological sciences | Alan R. Kimmel, Leung Kim, Jingchun Liu | |||
| The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. | Biological sciences | Adam C. Bell, Gary Felsenfeld, Adam G. West | |||
| The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70.(heat shock protein 70) | Biological sciences | Elizabeth A. Craig, Nikolaus Pfanner, Cindy Voisine, Nicole Zufall, Oliver von Ahsen, Wolfgang Voos | |||
| The rde-1 gene, RNA interference, and transposon silencing in C. elegans.(RNA interference-deficient, Caenorhabditis elegans)(Statistical Data Included) | Biological sciences | Jamie Fleenor, Lisa Timmons, Andrew Fire, Alla Grishok, Craig C. Mello, Madathia Sarkissian, Hiroaki Tabara, William G. Kelly | |||
| The role of chemokines in regulating cell migration during humoral immune responses.(Statistical Data Included) | Biological sciences | Antonius G. Rolink, Fritz Melchers, Christoph Schaniel | |||
| The sins of the fathers and mothers: genomic imprinting in mammalian development.(Mammalian Development: From Stem Cells to Aging) | Biological sciences | Shirley M. Tilghman | |||
| The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. | Biological sciences | Juliette Faraco, William Rogers, Robin Li, Emmanuel Mignot, Hiroshi Kadotani, Ling Lin, Xiaoyan Lin, Xiaohong Qiu, Pieter J. de Jong, Sieji Nishino | |||
| The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis.(matrix metalloproteinase) | Biological sciences | Zena Werb, Bing Huey, Joe W. Gray, Mina J. Bissell, Dan Pinkel, Mark D. Sternlicht, Andre Lochter, Carolyn J. Sympson, Jean-Philippe Rougier | |||
| The structural basis of ordered substrate binding by serotonin N-acetyltransferase: enzyme complex at 1.8 A resolution with a bisubstrate analog. | Biological sciences | David C. Klein, Fred Dyda, Alison Burgess Hickman, M.A.A. Namboodiri | |||
| The structure of the ligand-binding domain of neurexin I beta: regulation of LNS domain function by alternative splicing.(Statistical Data Included) | Biological sciences | Thomas C. Sudhof, Johann Deisenhofer, Thai Nguyen, Gabby Rudenko, Toharany Chelliah | |||
| The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. | Biological sciences | David Barford, Brian A. Hemmings, Matthew R. Groves, Neil Hanlon, Patric Turowski | |||
| The structure of threonyl-tRNA synthetase-tRNA(super Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site.(Transfer RNA) | Biological sciences | Pascale Romby, Joel Caillet, Mathias Springer, Bernard Rees, Chantal Ehresmann, Dino Moras, Rajaan Sankaranarayanan, Anne-Catherine Dock-Bregeon | |||
| The ties that bind: localization of the sister-chromatid cohesin complex on yeast chromosomes. | Biological sciences | Terry L. Orr-Weaver | |||
| The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene. | Biological sciences | H. Robert Horvitz, Barbara Conradt | |||
| The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis. | Biological sciences | Norbert Perrimon, Robert E. Boswell, Laufey T. Amundadottir, Kermit L. Carraway, Joseph B. Duffy, Christina Ghiglione | |||
| The Wilms tumor suppressor WT1 (ital) encodes a transcriptional activator of amphiregulin (ital). | Biological sciences | Daniel Haber, William Gerald, Rachel Palmer, Jonathan D. Oliner, Charles Paulding, Sean Bong Lee, Jenise Wong, Vivi B. Truong, Karen Huang, Doris Herzlinger, Kathryn A. Kolquist, Seung Kew Yoon | |||
| Three-dimensional structure of a complex between the death domains of Pelle and Tube.(Statistical Data Included) | Biological sciences | Steven A. Wasserman, Tsan Xiao, Stephen R. Sprang, Par Towb | |||
| Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. | Biological sciences | C. Ronald Kahn, Mark A. Magnuson, Rohit N. Kulkarni, Jens C. Bruning, Jonathon N. Winnay, Catherine Postic | |||
| Tomographic 3D reconstruction of quick-frozen, Ca(super.2+)-activated contracting insect flight muscle.(Statistical Data Included) | Biological sciences | Hiroyuki Sasaki, Yale E. Goldman, Kenneth A. Taylor, Clara Franzini-Armstrong, Holger Schmitz, Mary C. Reedy, Richard T. Tregear, Kate Poole, Carmen Lucaveche, Robert J. Edwards, Li Fan Chen, Hanspeter Winkler, Michael K. Reedy | |||
| Trading places on DNA - a three-point switch underlies primer handoff from primase to the replicative DNA polymerase. | Biological sciences | Mike O'Donnell, Alexander Yuzhakov, Zvi Kelman | |||
| Transcription factors in lymphocyte development - T and B cells get together. | Biological sciences | Laurie H. Glimcher, Harinder Singh | |||
| Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker. | Biological sciences | Gerard Campbell, Andrew Tomlinson | |||
| Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. | Biological sciences | Changill Ban, Wei Yang, Murray Junop | |||
| Transmembrane structure of an inwardly rectifying potassium channel. | Biological sciences | Lily Yeh Jan, Daniel L. Minor Jr., Susan J. Masseling, Nung Yuh Jan | |||
| Transport-dependent proteolysis of SREBP: relocation of Site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi. | Biological sciences | Michael S. Brown, Joseph L. Goldstein, Axel Nohturfft, Peter J. Espenshade, Russell A. DeBose-Boyd, Wei-Ping Li | |||
| Transport of proteins and RNAs in and out of the nucleus. | Biological sciences | Gideon Dreyfuss, Sara Nakielny | |||
| Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome. | Biological sciences | Roger D. Kornberg, Yahli Lorch | |||
| Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae. | Biological sciences | Helen R. Saibil, Jose L. Jimenez, Peter W. Andrew, Mike Parker, Robert J.C. Gilbert, Jamie Rossjohn, Shaoxia Chen, Ian J. Tickle | |||
| Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry. | Biological sciences | Tajib Mirzabekov, Michael Farzan, Craig Gerard, Hyeryun Choe, Richard Wyatt, Norma P. Gerard, Mark Cayabyab, Sodroski. Joseph, Peter Kolchinsky | |||
| Unlocking family secrets: K+ channel transmembrane domains. | Biological sciences | David E. Clapham | |||
| Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system. | Biological sciences | Peter Mombaerts, Paul Feinstein, Ivan Rodriguez | |||
| Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate.(Statistical Data Included) | Biological sciences | Menq-Jer Lee, Shobha Thangada, Kevin P. Claffey, Nicolas Ancellin, Catherine H. Liu, Michael Kluk, Mario Volpi, Ramadan I. Sha'afi, Timothy Hla | |||
| Vertebrate slit, a secreted ligand for the transmembrane protein Roundabout, is a repellent for olfactory bulb axons. | Biological sciences | David M. Ornitz, Jane Y. Wu, Yi Rao, Wei Wu, Hua-shun Li, Jin-hui Chen, Tanya Fagaly, Lijuan Zhou, Wenlin Yuan, Sophie Dupuis, Zhi-hong Jiang, William Nash, Carrie Gick | |||
| Vesicular tubular clusters between the ER and Golgi mediate concentration of soluble secretory proteins by exclusion from COPI-coated vesicles. | Biological sciences | Jan W. Slot, Hans J. Geuze, Jose A. Martinez-Menarquez, Judith Klumperman | |||
| Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures.(Statistical Data Included) | Biological sciences | Dennis H. Bamford, Roger M. Burnett, Stacy D. Benson, Bamford Jaana K.H. | |||
| Waves of malarial var-iations. | Biological sciences | Qijun Chen, Victor Fernandez, Per Hagblom, Mats Wahlgren, Staffan Svard | |||
| WEREWOLF, a MYB-related protein in Arabidopsis, is a position-dependent regulator of epidermal cell patterning.(Statistical Data Included) | Biological sciences | John Schiefelbein, Myeong Min Lee | |||
| What's critical for the critical period in visual cortex? | Biological sciences | Lawrence C. Katz | |||
| WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans. | Biological sciences | Roger J. Davis, Hideyuki Okano, Rueyling Lin, Craig C. Mello, Hitoshi Sawa, James R. Priess, Christian E. Rocheleau, Tae Ho Shin, Jun Yasuda | |||
| Yeast RNA polymerase II at 5 angstrom resolution.(Statistical Data Included) | Biological sciences | Roger D. Kornberg, David A. Bushnell, Grant J. Jensen, Jianhua Fu, Averell L. Gnatt, Nancy E. Thompson, Richard R. Gurgess, Peter R. David | |||
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.