Nature Medicine 1999 - Abstracts
| Nature Medicine 1999 | |||||
| Title | Subject | Authors | |||
|---|---|---|---|---|---|
| AAVant-garde gene therapy.(News & Views) | Health | Savio L.C. Woo, R. Michael Linden | |||
| A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency. | Health | Michael P. King, Eric A. Schon, Paolo Pinton, Rosario Rizzuto, Marisa Brini, Mercy Davidson | |||
| Accelerated transport and maturation of lysosomal alpha-galactoside A in Fabry lymphoblasts by an enzyme inhibitor. | Health | Satoshi Ishii, Jian-Qiang Fan, Naoki Asano, Yoshiyuki Suzuki | |||
| Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. | Health | Joe E. Springer, Robert D. Azbill, Pamela E. Knapp | |||
| Advocates push for new NIH office.(for autoimmune diseases)(News) | Health | Kristine Novak | |||
| A far-sighted view of myopia.(News & Views) | Health | Rachel O.L. Wong, Christine F. Wildsoet | |||
| A gene promotes anxiety in mice -- and also in scientists.(News & Views) | Health | Neil McNaughton | |||
| A higher standard for human research.(Editorial) | Health | ||||
| Allo-immunization elicits CD8+ T cell-derived chemokines, HIV suppressor factors and resistance to HIV infection in women. | Health | Robert Vaughan, Yufei Wang, Louisa Tao, Elaine Mitchell, Christopher Bravery, Pasqule Berlingieri, Paul Armstrong, Jenny Underwood, Thomas Lehner | |||
| AlphaV Beta5 integrin: a co-receptor for adeno-associated virus type 2 infection Summerford, Candace Bartlett, Jeffrey S. Samulski, Richard Jude. | Health | Richard Jude Samulski, Candace Summerford, Jeffrey S. Bartlett | |||
| Altered peptide ligands narrow the repertoire of cellular immune responses by interfering with T-cell priming. | Health | Adrian V.S. Hill, Sarah C. Gilbert, Magdalena Plebanski, Edwin A.M. Lee, Carolyn M. Hannan, Katie L. Flanagan, Michael B. Gravenor | |||
| An association between viral genes and human oncogenic alterations: the adenovirus E1A induces the Ewing tumor fusion transcript EWS-FLI1. | Health | Ana Martinez, Victor Fernandez, Javier Pardo, Ricardo Sanchez-Prieto, Enrique de Alava, Teresa Palomino, Juan Guinea, Silvia Cebrian, Matilde LLeonart, Pablo Cabello, Pilar Martin, Carlos San Roman, Rafael Bornstein, Fernando Diaz-Espada, Yve Barrios, Santiago Ramon y Cajal | |||
| A new peak in the ALPS.(autoimmune lymphoproliferative syndrome)(News & Views) | Health | Alain Fischer, Francoise Le Deist, Frederic Rieux-Laucat | |||
| Anti-cancer activity of targeted pro-apoptotic peptides. | Health | Lisa M. Ellerby, Dale E. Bredesen, Renata Pasqualini, Wadih Arap, Erkki Ruoslahti, Stanislaw Krajewski, H. Michael Ellerby, Renate Kain, Rebecca Andrusiak, Gabriel Del Rio, Christian R. Lombardo, Rammohan Rao | |||
| A partnership that delivers.(News and Views)(Statistical Data Included) | Health | Kenneth S. Kosik | |||
| Are thalamocortical rhythms the rosetta stone of a subset of neurological disorders?(News & Views) | Health | David A. McCormick | |||
| Aspirin for cancer.(News & Views) | Health | Steven J. Shiff, Basil Rigas | |||
| A universal influenza A vaccine based on the extracellular domain of the M2 protein. | Health | Walter Fiers, Sabine Neirynck, Tom Deroo, Xavier Saelens, Peter Vanlandschoot, Willy Min Jou | |||
| Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. | Health | Felix Mor, Michal Schwartz, Gila Moalem, Raya Leibowitz-Amit, Eti Yoles, Irun R. Cohen | |||
| Azodicarbonamide inhibits T-cell responses in vitro and in vivo. | Health | Michel Goldman, Oberdan Leo, Joel Tassignon, Jamila Ismaili, Alain Le Moine, Francois Laethem, Michel Vandevelde | |||
| B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. | Health | Koji Tamada, Gefeng Zhu, Lieping Chen, Haidong Dong | |||
| Big deal about a little insulin. | Health | Jeffrey S. Flier | |||
| Bioinformatics an NIH priority.(National Institutes of Health) | Health | Marlene Cimons | |||
| Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell mediated autoimmune diseases. | Health | Zheng Wang, Tong Zhou, Richard S. Jope, Ling Long, Pingar Yang, Di Lui | |||
| Blasting away leukemia. | Health | Paul W. Kincade | |||
| Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo.(Statistical Data Included) | Health | Alan R. Saltiel, Judith S. Sebolt-Leopold, David T. Dudley, Roman Herrera, Keri Van Becelaere, Amy Wiland, Richard C. Gowan, Haile Tecle, Stephen D. Barrett, Alexander Bridges, Sally Przybranowski, W.R. Leopold | |||
| Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance. | Health | Terry B. Strom, Xin Xiao Zheng, Laurence A. Turka, Andrew D. Wells, Yongsheng Li, Xian Chang Li | |||
| Bridge over troubled waters. | Health | Hannu Sariola, Lennart. Philipson | |||
| Call to buy nevirapine for developing countries.(News) | Health | Karen Birmingham, Beatrice Renault | |||
| Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the I(kappa)B(alpha)/NF-(kappa)B pathway in limb girdle muscular dystrophy type 2A. | Health | Michel Fardeau, Jacques S. Beckmann, Ronald T. Hay, Marianne Martin, Stephen Baghdiguian, Isabelle Richard, Nathalie Bourg, Francoise Pons, Chatherine Astier, Raymond Chemaly, Georges Halaby, Jacques Loiselet, Louise V.B. Anderson, Adolfo Lopez de Munain, Paul Mageat, Gerard Lefranc | |||
| Cancer therapy using a self-replicating RNA vaccine.(Statistical Data Included) | Health | Nicholas P. Restifo, Rong-Fu Wang, Wolfgang W. Leitner, Han Ying, Tal Z. Zaks, Kari R. Irvine, Udai S. Kammula, Francesco M. Marincola | |||
| Cancer vaccine strategies get bigger and better.(News & Views) | Health | David T. Curiel, Tanja D. de Gruijl | |||
| Cartilage to bone - angiogenesis leads the way. | Health | Michael Klagsbrun, Jay Harper | |||
| Caspase inhibition reduces apoptosis and increases survival of nigral transplants. | Health | Patrik Brundin, Hakan Widner, Pierluigi Nicotera, Gabriele S. Schierle, Oskar Hansson, Marcel Leist | |||
| Catalytic activity of antibodies against factor VIII in patients with hemophilia A. | Health | Michel D. Kazatchkine, Yvette Sultan, Johan Hoebeke, Sebastien Lacroix-Desmazes, Alexandre Moreau, Sooryanarayana, Cecile Bonnemain, Natalie Stieltjes, Anastas Pashov, Srinivas V. Kaveri | |||
| CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy.(Statistical Data Included) | Health | Ton N.M. Schumacher, Cornelis J.M. Melief, Stephen P. Schoenberger, Rene E.M. Toes, Ellen I.H. van der Voort, Rienk Offringa, Linda Diehl, Annemieke Th. den Boer | |||
| CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. | Health | Ruth R. French, H.T. Claude Chan, Alison L. Tutt, Martin J. Glennie | |||
| CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia. | Health | D. Bron, V. Mateo, L. Lagneaux, G. Biron, M. Armant, G. Delespesse, M. Sarfati | |||
| Characterization of circulating T cells specific for tumor-associated antigens in melonoma patients. | Health | Denise Johnson, Peter P. Lee, Mark M. Davis, Mario Roederer, John Thompson, Philip D. Greenberg, Cassian Yee, Jeffrey S. Weber, Dirk Brockstedt, Peter A. Savaga, Lawrence Fong, Susan Swetter | |||
| Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials. | Health | D. Stone, R.A. Dewey, G. Morrissey, C.M. Cowsill, F. Bolognani, N.J.F. Dodd, T.D. Southgate, D. Klatzmann, H. Lassmann, M.G. Castro, P.R. Lowenstein | |||
| Clinical applications of angiogenic growth factors and their inhibitors.(Review) | Health | Napoleone Ferrara, Kari Alitalo | |||
| Clinical research is dead; long live clinical research. | Health | John I. Bell | |||
| Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis.(Statistical Data Included) | Health | Mark D. Hulett, Craig Freeman, Brenton J. Hamdorf, Rohan T. Baker, Matthew J. Harris, Christpher R. Parish | |||
| Cluster headache: phrenology revisited? | Health | Cornelius Weiller, Michel Rijntjes | |||
| Cocaine addiction therapy -- are we partially there?(News & Views) | Health | George F. Koob, S. Barak Caine | |||
| Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma. | Health | Elaine S. Jaffe, Dan L. Longo, Larry W. Kwak, Barry L. Gause, Stephen P. Creekmore, Robin Pennington, Carol B. Kobrin, Craig W. Reynolds, Maurizio Bendandi, Christopher D. Gocke, Floyd A. Benko, Lars A. Sternas, Thelma M. Watson, Patricia L. Duffey | |||
| Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine. | Health | Barbara Ensoli, Lennart Akerblom, Alessandra Borsetti, Silvia Baroncelli, Aurelio Cafaro, Antonella Caputo, Claudio Fracasso, Maria T. Maggiorella, Delia Goletti, Monica Pace, Leonardo Sernicola, Martin L. Koanga-Mogtomo, Monica Betti, Roberto Belli, Franco Corrias, Stefano Butto, Jonathan Heeney, Paola Verani, Fausto Titti | |||
| Conversion of tumor-specific CD4(super.+) T-cell tolerance to T-cell priming through in vivo ligation of CD40.(Statistical Data Included) | Health | Ivan Borrello, Eduardo M. Sotomayor, Erev Tubb, Frederique-Marie Rattis, Harold Bien, Zhengbin Lu, Steve Fein, Stephen Schoenberger, Hyam I. Levitsky | |||
| Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors. | Health | Mark A. Kay, Leonard Meuse, Darrel W. Stafford, Dwight A. Bellinger, Marjorie S. Read, Kenneth M. Brinkhous, Timothy C. Nichols, Richard O. Snyder, Carol Miao, Julie Tubb, Brian A. Donahue, Hui-Feng Lin, Salil Patel, Arthur R. Thompson | |||
| Correlation between structural and functional changes in brain in an idiopathic headache syndrome.(Statistical Data Included) | Health | K.J. Friston, R.S.J. Frackowiak, A. May, J. Ashbruner, C. Buchel, D.J. McGonigle, P.J. Goadsby | |||
| COX-2 inhibitors: Is there cause for concern?(cyclooxygenase 2) | Health | Karen Seibert, James Lefkowith, Catherine Tripp, Peter Isakson, Philip Needleman | |||
| COX-2: promoting tolerance.(oral tolerance) | Health | Olivier Morteau | |||
| Cyclooxygenase-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen. | Health | William F. Stenson, Rodney D. Newberry, Robin G. Lorenz | |||
| Cytomegalovirus US2 destroys two components of the MHC class II pathway, preventing recognition by CD4+ cells. | Health | Peter Cresswell, Jay A. Nelson, David C. Johnson, Yoram Altschuler, Stanley R. Riddell, Thomas R. Jones, Roman Tomazin, Jessica Boname, Nagendra R. Hegde, David M. Lewinsohn | |||
| Deal creates lead cloning company.(includes related article on WHO's hosting of Web discussion on xenotransplantation policy) | Health | David Firn | |||
| Death, destruction, danger and dendritic cells.(News & Views) | Health | Jonathan M. Austyn | |||
| Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y(sub)1-deficient mice. | Health | MyTrang Nguyen, Thomas M. Coffman, Beverly H. Koller, Jean-Etienne Fabre, Anne Latour, Jayne A. Keifer, Laurent P. Audoly | |||
| Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells Bossi, G. Griffiths, G.M. | Health | G. Bossi, G.M. Griffiths | |||
| Delivering genes to the heart -- right where it counts!(News and Views)(Statistical Data Included) | Health | Elizabeth Nabel | |||
| Design of angiotensin converting enzyme inhibitors.(Clinical Medical Research Award) | Health | David W. Cushman, Miguel A. Ondetti | |||
| Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes. | Health | Joseph M. Metzger, Daniel E. Michele, Faris P. Albayya | |||
| Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans. | Health | D. Schmidt, M. Hellerstein, M.B. Hanley, D. Cesar, S. Siler, C. Papageorgopoulos, E. Wieder, R. Hoh, R. Neese, D. Macallan, S. Deeks, J.M. McCune | |||
| Does our DNA determine when we sleep?(News & Views) | Health | Alfred J. Lewy, Clifford M. Singer | |||
| Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis. | Health | Shlomo Melmed, Anthony P. Heaney, Gregory A. Horwitz, Zhiyong Wang, Regina Singson | |||
| Effect of interleukin-2 on the pool of latently infected, resting CD4(super.+) T cells in HIV-1-infected patients receiving highly active anti-retroviral therapy. | Health | Lawrence Corey, Joseph A. Kovacs, H. Clifford Lane, Tae-Wook Chun, Delphine Engel, Anthony S. Fauci, Richard T. Davey Jr., Julia A. Metcalf, Sohee Park, Claire W. Hallahan, Mark Dybul, Stehanie B. Mizell, Maria Fishette, JoAnn M. Mican, M. Michelle Berrey | |||
| Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression. | Health | Julie Overbaugh, LaRene Kuller, David B. Anderson, Peter Dailey, Jason T. Kimata | |||
| Endotoxin opens the Tollgates to innate immunity.(News and Views)(Statistical Data Included) | Health | Richard J. Ulevitch | |||
| Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon. | Health | Hiroshi Takahashi, Toshiharu Eto | |||
| Equivalent amplification of intrinsically variable nucleic acid sequences by multiple-primer-induced overlapping amplification assay: applications for universal detection and quantitation. | Health | Jean-Marie Andrieu, Wei Lu, Li Cao, Likia Ty, Marine Arlie | |||
| Estrogen hits the surface.(estrogen acts in the cytosol as well as in the nucleus)(News & Views) | Health | Peter Collins, Carolyn Webb | |||
| Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. | Health | Ian Dransfield, Christopher Haslett, Seamas C. Donnelly, Tariq Sethi, Robert C. Rintoul, Sarah M. Moore, Alison C. MacKinnon, Donald Salter, Chin Choo, Edwin R. Chilvers, Robert Strieter | |||
| Familial advanced sleep-phase syndrome: a short-period circadian rhythm variant in humans. | Health | Bryan Jones, Louis J. Ptacek, Scott S. Campbell, Patricia J. Murphy, Christopher R. Jones, Stephanie E. Zone, Fred Cooper, Alison DeSano, Laura Czajkowski | |||
| Fatal attraction: when chaperone turns harlot.(News & Views) | Health | Roy Quinlan, Paul van den Ijssel | |||
| Febrile convulsions: a 'benign' condition?(News & Views) | Health | Dimitri M. Kullmann, Matthew C Walker | |||
| Febrile seizures in the developing brain result in persistent modification of neuronal excitability in limbic circuits. | Health | Kang Chen, Tallie Z. Baram, Ivan Soltesz | |||
| Fibrinogen-coated albumin microcapsules reduce bleeding in severely thrombocytopenic rabbits. | Health | Marcel Levi, Roy Harris, Jack Levin, Jan Wouter ten Cate, Philip W. Friederich, Sarah Middleton, Philip de Groot, Ya Ping Wu, Bart J. Biemond, Harry F.G. Heijnen | |||
| Fighting arthritis with a senescence gene. | Health | Dennis A. Carson, Norio Haneji | |||
| Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity. | Health | Peter G. Wells, Toufan Parman, Michael J. Wiley | |||
| From Agouti to Pomc -- 100 years of fat blonde mice.(News & Views) | Health | Greg Barsh | |||
| Gamma/delta T cells provide a breath of fresh air for asthma research.(News & Views) | Health | P.D. Sly, Patrick G. Holt | |||
| Gene expression profiles of laser-captured adjacent neuronal subtypes.(New Technology) | Health | Lin Luo, Michael R. Jackson, Ranelle C. Salunga, Hongqing Guo, Anton Bittner, K.C. Joy, Jose E. Galindo, Huinian Xioa, Kathryn E. Rogers, Jackson S. Wan, Mark G. Erlander | |||
| Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2. | Health | Anne Girod, Martin Ried, Christiane Wobus, Harald Lahm, Kristin Leike, Jurgen Kleinschmidt, Gilbert Deleage, Michael Hallek | |||
| Gene transfer into CD4(super.+) T lymphocytes: green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses.(New Technology)(Statistical Data Included) | Health | Alexander Flugel, Hartmut Wekerle, Michael Willem, Tomasz Berkowicz | |||
| German cutbacks hurt science.(News) | Health | Michael Simm | |||
| Getting to the heart of DiGeorge syndrome.(News & Views) | Health | Seigo Izumo, Martina Schinke | |||
| Global elimination of trachoma: How frequently should we administer mass chemotherapy? | Health | Travis Porco, Tom Lietman, Chandler Dawson, Sally Blower | |||
| Graft tolerance: a duel of two signals. | Health | Polly Matzinger | |||
| Grants will determine European malaria vaccine future.(News) | Health | Karen Birmingham, Hannah Wunsch | |||
| Heparanase: Breaking down barriers in tumors. | Health | Suzanne A. Eccles | |||
| Hepatitis B virus transgenic mouse model of chronic liver disease. | Health | Linda D. Siracusa, Jonathan Larkin, Marcy Clayton, Bill Sun, Claire E. Perchonock, Judith L. Morgan, Frank H. Michaels, Mark A. Feitelson | |||
| HIV-1 and HAART: a time to cure, a time to kill.(highly active antiretroviral therapy) | Health | Michael S. Saag, J. Michael Kilby | |||
| HIV-1 entry inhibitors: evading the issue. | Health | John P. Moore, Nelson L. Michael | |||
| HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. | Health | R. Wang, K. Williams, A. Mann, D. Fisher, M. Stevenson, S. Swingler, J.-M. Jacque, B. Brichacek, V.G. Sasseville, A.A. Lackner, E.N. Janoff | |||
| HIV-1 Nef protein: an invitation to a kill.(News & Views) | Health | Bryan R. Cullen | |||
| HIV-1 neutralizing antibodies: How full is the bottle?(News and Views)(Statistical Data Included) | Health | Dennis R. Burton, John P. Moore | |||
| HIV-1-specific CD4(super.+) T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression. | Health | Richard A. Koup, Louis J. Picker, Mark Connors, Christine J. Pitcher, Claudia Quittner, Dolores M. Peterson, Vernon C. Maino | |||
| How the immune system puts the brain to sleep.(tumor necrosis factor can affect central nervous system)(News & Views) | Health | Daniela N. Mannel, Rainer H. Straub | |||
| Human embryonic stem cells: the future is now.(News and Views)(Statistical Data Included) | Health | Gordon Keller, H. Ralph Snodgrass | |||
| Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2 Qing, Keyun Mah, Cathryn Hansen, Jonathan Zhou, Shangzhen Dwarki, Varavani Srivastava, Arun. | Health | Jonathan Hansen, Keyun Qing, Cathryn Mah, Shangzhen Zhou, Varavani Dwarki, Arun Srivastava | |||
| Human therapeutic cloning.(Commentary) | Health | Robert P. Lanza, Jose B. Cibelli, Michael D. West | |||
| Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library. | Health | Charles A. Janeway Jr., Irene Visintin, Eric G. Pamer, F. Susan Wong, Jaana Karttunen, Caroline Dumont, Li Wen, Ingrid M. Pilip, Nilabh Shastri | |||
| Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease. | Health | Bibiana Bielekova, Irene Cortese, Takayuki Kondo, Bruno Gran, Henry F. McFarland, Roland Martin, Stephen E. Straus, Richard (French biblical critic) Simon, Clemencia Pinilla, Adriana Marques, Bernhard Hemmer, Yingdong Zhao, Jeannick Pascal, Abraham Tzou, Richard Houghten | |||
| Impaired myocardial angiogenesis and eschemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF(sub.164) and VEGF(sub.188). | Health | Andras Nagy, Patricia A. D'Amore, Vijay V. Kakkar, Florea Lupu, Mieke Dewerchin, Desire Collen, Dieter Nuyens, Willem Flameng, Lieve Moons, Ingeborg Stalmans, David T. Shima, Jean-Claude Perriard, Elisabeth Ehler, Koen Brusselmans, Virginie Mattot, Peter Cameliet, Yin-Shan Ng, Gregor Theilmeire, Ivo Cornelissen | |||
| Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. | Health | Solomon H. Snyder, Christopher A. Ross, J. Timothy Greenamyre, Alan H. Sharp, Akira Sawa, Gordon W. Wiegand, Jillian Cooper, Russell L. Margolis, Joseph F. Lawler Jr. | |||
| Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. | Health | Mark P. Mattson, George M. Martin, Carol B. Ware, Qing Guo, Weiming Fu, Bryce L. Sopher, Miles W. Miller | |||
| Inducible cyclooxygenase may have anti-inflammatory properties. | Health | Derek W. Gilroy, D.A. Willoughby, P.R. Colville-Nash, J. Chivers, M.J. Paul-Clark | |||
| Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. | Health | Ted M. Dawson, Valina L. Dawson, Miquel Vila, Serge Przedborski, Gabriel T. Liberatore, Vernice Jackson-Lewis, Slobodanka Vukosavic, Allen S. Mandir, W. Geoffrey McAuliffe | |||
| Induction of an oncogenic fusion protein by a viral gene -- a new chapter in an old story.(News & Views) | Health | Terry Hermiston, David Kirn | |||
| Induction of antigen-specific immunosuppression by CD95L cDNA-transfected 'killer' dendritic cells. | Health | Michael Walters, Hideo Yagita, Ko Okumura, Hiroyuki Matsue, Keiko Matsue, Akira Takashima | |||
| Induction of the p16(super.INK4a) senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis.(Statistical Data Included) | Health | Hiroshi Ito, Katsuiku Hirokawa, Naoki Inoue, Nobuyuki Miyasaka, Ken Taniguchi, HItoshi Kohsaka, Yoshio Terada | |||
| Inflammatory pathways and cardiac repair: the affliction of infarction.(News & Views) | Health | Kenneth R. Chien, Kirk U. Knowlton | |||
| Inflammatory thoughts about glioma gene therapy.(News & Views) | Health | Tammy Kielian, William F. Hickey | |||
| Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. | Health | I. James Sarfeh, Hongtao Wang, Michael K. Jones, Brigitta M. Peskar, Ellis Levin, Rabiha M. Itani, Andrzej S. Tarnawski | |||
| Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1. | Health | Takeshi Watanabe, Manabu Nakashima, Kenzo Sonoda | |||
| Inhibition of HIV replication by dominant negative militants of Sam68, a functional homolog of HIV-1 Rev. | Health | Weidong Xu, David W. Rose, Flossie Wong-Staal, Thipparthi R. Reddy, Janathan K. L. Mau, Christopher D. Goodwin, Hengli Tang, Kenneth Frimpong, Modem Suhasini | |||
| Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. | Health | A. Baker, S. Heymans, A. Luttun, D. Nuyens, G. Theilmeier, E. Creemers, L. Moons, G.D. Dyspersin, J.P.M. Cleutjens, M. Shipley, A. Angellilo, M. Levi, O. Nube, E. Keshet, F. Lupu, J.-M. Herbert, J.F.M. Smits, S.D. Shapiro, M. Baes, M. Borgers, D. Collen, M.J.A.P. Daemen, P. Carmeliet | |||
| Inhibition of telomerase limits the growth of human cancer cells. | Health | Robert A. Weinberg, William C. Hahn, Joan H.M. Knoll, Mary W. Brooks, Sheila A. Stewart, Roderick L. Beijersbergen, Matthew Meyerson, Shoshana G. York, Elinor Eaton, Akiko Kurachi | |||
| Inhibition of virus-induced neuronal apoptosis by Bax.(Statistical Data Included) | Health | Kazuyoshi Ueno, Jennifer Lewis, George A. Oyler, Yih-ru Fannjiang, B. Nelson Chau, James Vornov, Stanley Korsmeyer, Shifa Zou, J.Marie Hardwick | |||
| Instability of adenoviral vectors during transport and its implication for clinical studies.(New Technology) | Health | Cassandra Nyberg-Hoffman, Estuardo Aguilar-Cordova | |||
| Institute surprise for Italian scientists.(Istituto Superiore della Sanita will become equivalent to US NIH)(News) | Health | Martina Ballmaier | |||
| In stroke, complement will get you nowhere.(News & Views) | Health | Gregory J. Del Zoppo | |||
| Integration of endoplasmic reticulum signaling in health and disease. | Health | William E. Balch, Meir Aridor | |||
| Interleukin-4 receptor-directed cytotoxin therapy of AIDS-associated Kaposi's sarcoma tumors in xenograft model.(Statistical Data Included) | Health | Robert J. Kreitman, Ira Pastan, Raj K. Puri, Syed R. Husain | |||
| Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis. | Health | Andrej Tarkowski, Guo-Min Deng, Ing-Marie Nilsson, Margareta Verdrengh, L. Vincent Collins | |||
| In vivo migration and function of transferred HIV-1-specific cytotoxic T cells. | Health | Lawrence Corey, Bruce K. Patterson, Scott J. Brodie, Philip D. Greenberg, Stanley R. Riddell, Deborah A. Lewinsohn, Daniel Jiyampa, John Krieger | |||
| Ion channels: from idea to reality.(Basic Medical Research Award) | Health | Roderick MacKinnon, Bertil Hille, Clay M. Armstrong | |||
| Is an HIV vaccine possible? | Health | Tomas Hanke, Andrew J. McMichael | |||
| Is autoimmunity coming to a Fas(t) end?(News & Views) | Health | Thomas Brunner, Christoph Mueller | |||
| Is calcium the 'cure' for dilated cardiomyopathy?(News & Views) | Health | R. John Solaro | |||
| Is it thee or me? Autoimmunity in Lyme disease.(News & Views) | Health | Mark S. Klempner, Brigitte T. Huber | |||
| Is six billion a reason to celebrate?(human population reaches 6 billion in October, 1999)(Editorial) | Health | ||||
| Killing HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein. | Health | Lee Ratner, Natalie A. Lissy, Steven F. Dowdy, Adita M. Vocero-Akbani, Nancy Vander Heyden | |||
| Latent infection of CD4(super.+) T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. | Health | Richard E. Chaisson, Thomas C. Quinn, Charles Flexner, Joel Blankson, Robert F. Siliciano, Diana Finzi, Joseph B. Margolick, Janet D. Siliciano, Franco Lori, Julianna Lisziewicz, Eric Rosenberg, Karen Chadwick, Bruce Walker, Theodore Pierson, Kendall Smith, Stephen Gange, Joel Gallant | |||
| Latent reservoirs of HIV infection: flushing with IL-2?(interleukin-2) | Health | David A. Cooper, Sean Emery | |||
| Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia. | Health | Christine Chomienne, Florence Smadja-Joffe, Yue Li, Rachida-Sihem Charrad, Bertrand Delpech, Nicole Balitrand, Denis Clay, Claude Jasmin | |||
| Linking innate and adaptive immunity.(News & Views) | Health | Jacques Banchereau, Karolina Palucka | |||
| Local people threaten chimp sanctuary. | Health | Kris Novak | |||
| Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector. | Health | Katherine A. High, Roland W. Herzog, Edmund Y. Yang, Linda B. Couto, J. Nathan Hagstrom, Dan Elwell, Paul A. Fields, Melissa Burton, Dwight A. Bellinger, Marjorie S. Read, Kenneth M. Brinkhous, Gregory M. Podsakoff, Timothy C. Nichols, Gary J. Kurtzman | |||
| Long-term cure of the photosensitivity of murine erhthropoietic protoporphyria by preselective gene therapy.(Statistical Data Included) | Health | Micheline M. Mathews-Roth, Robert Pawliuk, Philippe Leboulch, Thomas Bachelot, Robert J. Wise | |||
| Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis.(Statistical Data Included) | Health | Iris Pecker, Israel Vlodavsky, Yael Friedmann, Michael Elkin, Helena Aingorn, Ruth Atzmon, Rivka Ishai-Michaeli, Menachem Bitan, Orit Pappo, Tuvia Peretz, Israel Michal, Larissa Spector | |||
| MEK wars, a new front in the battle against cancer. | Health | Nicholas S. Duesbery, Craig P. Webb, George F. VandeWoude | |||
| Mental illness and the sciences of brain and behavior.(Special Achievement in Medical Science Award) | Health | Seymour S. Kety | |||
| Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.(Statistical Data Included) | Health | George Kollias, Robert J. Moore, Frances Balkwill, Manolis Pasparakis, Barrett Rollins, David M. Owens, Gordon Stamp, Caroline Arnott, Frances Burke, Nick East, Hazel Holdsworth, Lynn Turner | |||
| Millenium money for Japanese scientists.(News) | Health | Robert Triendl | |||
| Monitoring simultaneous subcellular events in vitro by means of coherent multiprobe fluorescence. | Health | Douglas R. Plymale, Jeffrey R. Haskins, Felix A. De la Iglesia | |||
| MRP4: a previously unidentified factor in resistance to nucleoside-based antiviral drugs. | Health | John D. Schuetz, Patricia M. Flynn, Alok Kumar, Daxi Sun, Michele C. Connelly, Sheela G. Paibir, R.V. Srinivas, Arnold Fridland | |||
| Natural adjuvants: endogenous activators of dendritic cells. | Health | Polly Matzinger, Stefania Gallucci, Martijn Lolkema | |||
| Negative regulation of airway responsiveness that is dependent on gamma/delta T cells and independent of alpha/beta T cells. | Health | Erwin W. Gelfand, Willi Born, Rebecca O'Brien, Katsuyuki Takeda, Jurgen Schwarze, Michael Lahn, Arihiko Kanehio, Anthony Joetham, Gabriele Kohler | |||
| Neural control of mechanical ventilation in respiratory failure.(New Technology) | Health | Yoanna Skrobik, Christer Sinderby, Paolo Navalesi, Jennifer Beck, Norman Comtois, Sven Friberg, Stewart B. Gottfried, Lars Lindstrom | |||
| Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral aclerosis. | Health | Robert J. Ferrante, M. Flint Beal, Peter Klivenyi, Russell T. Matthews, Michail B. Bogdanov, Autumn M. Klein, Ole A. Andreassen, Gerald Mueller, Marieke Wermer, Rima Kaddurah-Daouk | |||
| Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations. | Health | Tahir A. Rizvi, Marcia L. Kalish, Harriet L. Robinson, Jeffrey D. Lifson, David C. Montefiori, R. Paul Johnson, Shiu-Lok Hu, Shan Lu, Kelledy H. Manson, Gail P. Mazzara, Dennis L. Panicali, James G. Herndon, Rhona Glickman, Maria A. Candido, Shari I. Lydy, Michael S. Wyand, Harold M. McClure | |||
| New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: the Minipellet. | Health | Hiroshi Itoh, Yutaka Nagai, Takahiro Ochiya, Masaaki Terada, Yasushi Takahama, Shunji Nagahara, Yoshihiro Sumita, Akihiko Hisada | |||
| New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury. | Health | Andrew Baker, Colin N. Chesterman, Levon M. Khachigian, Fernando S. Santiago, Harry C. Lowe, Mary M. Kavurma, David G. Atkins | |||
| NF-(kappa)B is activated and promotes cell death in focal cerebral ischemia. | Health | Armin Schneider, Ana Martin-Villalba, Markus Schwaninger, Falk Weih, Johannes Vogel, Thomas Wirth | |||
| Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor. | Health | Hessameh Hassani, Peter Thoren, Patrik Ernfors, Ernest Arenas, Philippe Naveiljan, Josep M. Canals, A. Jonas Ekstrand, Asa Larefalk, Vijay Chhajlani, Karin Gedda, Lennart Svensson | |||
| NOS knockouts and neuroprotection.(nitric oxide synthase)(News & Views) | Health | M. Flint Beal, Thomas Grunewald | |||
| Novartis expands academic research funding.(News) | Health | Victor D. Chase | |||
| Nucleotides and cd39: principal modulatory players in hemostasis and thrombosis. | Health | Herbert Zimmerman | |||
| Obesity: autonomic circuits versus feeding. | Health | Katsunori Nonogaki | |||
| Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. | Health | Linda Yaswen, Nicole Diehl, Miles B. Brennan, Ute Hochgeschwender | |||
| Of methods and mapping. | Health | Terence H. Rabbitts | |||
| Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. | Health | David N. Louis, E. Antonio Chiocca, Dianne Finkelstein, Keiro Ikeda, Tomotsugu Ichikawa, Hiroaki Wakimoto, Jonathan S. Silver, Thomas S. Deisboeck, Griffith R. Harsh IV, Raymond T. Bartus, Fred H. Hochberg | |||
| Ongoing HIV dissemination during HAART.(Commentary) | Health | Dimiter S. Dimitrov, William E. Paul, Jaap Goudsmit, Frank de Wolf, Robert Yarchoan, Mark B. Feinberg, Michael Polis, Zehava Grossman, Zvi Grossman, Itschak Levi, Shirley Jankelevich, Jacob Boon, Joep M.Am Lange | |||
| Orthogonal polarization spectral imaging: a new method for study of the microcirculation. | Health | James W. Winkelman, Warren Groner, Anthony G. Harris, Can Ince, Gerrit J. Bouma, Konrad Messmer, Richard G. Nadeau | |||
| PACHA adopts more lenient stance to government efforts.(President's Advisory Council on HIV/AIDS)(News) | Health | Myrna Watanabe | |||
| Painful stimulation suppresses joint inflammation by inducing shedding of L-selectin from neutrophils. | Health | Jon D. Levine, Steven D. Rosen, Holly J. Strausbaugh, Paul G. Green, Ernest Lo, Kirsten Tangemann, David B. Reichling | |||
| Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. | Health | Fabio Facchetti, Marco Colonna, Antonio Lanzavecchia, Marina Cella, Hideo Nakajima, David Jarrossay, Olga Alebardi | |||
| Prion replication -- once again blaming the dendritic cell.(News & Views) | Health | Pierluigi Gambetti, Man-Sun Sy | |||
| Production of atypical measles in rhesus macaques: evidence for disease mediated by immune e complex formation and eosinophils in the presence of fusion-inhibiting antibody. | Health | Fernando P. Polack, Alexandra Valsamakis, Robert J. Adams, Diane E. Griffin, Hossein C. Nousari, Paul G. Auwaerter, Sok-H. Lee, Kristin M. Leiferman, Arwind Diwan | |||
| Protective effects of C5a blockade in sepsis.(Statistical Data Included) | Health | Peter A. Ward, Markus Huber-Lang, Roscoe L. Warner, Boris J. Czermak, Vidya Sarma, Carl L. Pierson, Nicolas M. Bless, Hagen Schmal, Hans Peter Friede | |||
| Protective effects of C5a blockade in sepsis.(Statistical Data Included) | Health | Peter A. Ward, Roscoe L. Warner, Boris J. Czermak, Vidya Sarma, Carl L. Pierson, Nicolas M. Bless, Hagen Schmal, Huber-Lang Markus, Hans Peter Friedl | |||
| Rapid selection of complement-inhibiting protein variants in group A Streptococcus epidemic waves. | Health | Anne Schuchat, Allison McGeer, James M. Musser, Nancy P. Hoe, Mengyao Liu, Donald E. Low, Benjamin Schwartz, Yun-Xin Fu, Jaana Vuopio-Varkila, Kazumitsu Nakashima, Slawomir Lukomski, Diana Grigsby, Parichher Kordari, Shu-Jun Dou, Xi Pan, Saara Salmelinna, Steven Naidich, Dsvid De Lorenzo | |||
| Regulation of Fas ligand expression and cell death by apoptosis-linked gene 4. | Health | Luciano D'Adamio, Emanuela Lacana | |||
| Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor. | Health | Shay Soker, Joyce Bischoff, Wei Shen, Lois E.H. Smith, Carole Perruzzi, Fumi Kinose, Xianghong Xu, Gregory Robinson, Sam Driver, Bei Zhang, James M. Schaeffer, Donald R. Senger | |||
| Replacing competition with cooperation.(Editorial) | Health | ||||
| Requirement for CD154 in the progression of atherosclerosis. | Health | Richard A. Flavell, Iqbal S. Grewal, Leonid Gorelik, Esther Lutgens, Mat J.A.P. Daemen, Ebo D. De Muinck, Victor E. Koteliansky | |||
| Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. | Health | Terry B. Strom, Xin Xiao Zheng, Laurence A. Turka, Zihao Wu, Wayne W. Hancock, Gabriel Nunez, Andrew D. Wells, Yongsheng Li, Xian Chang Li, Matthew C. Walsh, Tang. Aimin, Mohamed Sayegh | |||
| Retinitis pigmentosa: rod photoreceptor rescue by a calcium-channel blocker in the rd mouse. | Health | Maria Frasson, Jose A. Sahel, Michel Fabre, Manuel Simonutti, Henri Dreyfus, Serge Picaud | |||
| Reversal of virus-induced systemic shock and respiratory failure by blockade of the lymphotoxin pathway. | Health | Jeffrey L. Browning, John D. Altman, Robert D. Schreiber, Rafi Ahmed, Sherif R. Zaki, Wun-Ju Shieh, Maryann T. Puglielli, Avery W. Brewer, M.B.A. Oldstone | |||
| Runt domains take the lead in hematopoiesis and osteogenesis.(News & Views) | Health | Yoshiaki Ito, Milton H. Werner, Katsuya Shigesada | |||
| Russell Ross, 1929-1999.(Obituary) | Health | ||||
| SAP-less chromatin triggers systemic lupus erythematosus.(Serum amyloid protein) | Health | Michael C. Carroll, Elahna Paul | |||
| Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. | Health | K. Stewart, A. Williams, M.E. Bruce, H. Fraser, K.L. Brown, D.L. Ritchie, N.A. Mabbott, W.I. Morrison | |||
| Seeking the ghost of worms past.(parasitic worms)(Commentary) | Health | Tinker Ready | |||
| Selection, the mutation rate and cancer: ensuring that the tail does not wag the dog.(Commentary) | Health | Walter Bodmer, Ian Tomlinson | |||
| Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury. | Health | Richard J. Traystman, Marc Yudkoff, Barbara S. Slusher, James J. Vornov, Ajit G. Thomas, Patricia D. Hurn, Izumi Harukuni, Anish Bhardwaj, Michael B. Robinson, Paul Britton, X.-C. May Lu, Frank C. Tortella, Krystyna M. Wozniak, Beth M. Potter, Paul F. Jackson | |||
| Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity. | Health | G.A. Tennent, M.B. Pepys, J. Herbert, M.C.M. Bickerstaff, M. Botto, W.L. Hutchinson, A. Bybee, D.A. Mitchell, H.T. Cook, P.J.G. Butler, M.J. Walport | |||
| Signaling mismatch repair in cancer.(News & Views) | Health | Richard Fishel | |||
| South Africa: setting the wrong example.(Editorial) | Health | ||||
| Spending spree to end Canadian `brain drain.'(Prime Minister creates 2,000 research chairs)(News) | Health | Brian Hoyle | |||
| Spontaneous combined hyperlipidemia, coronary heart disease and decreased survival in Dahl salt-sensitive hypertensive rats transgenic for human cholesteryl ester transfer protein. | Health | Ronald M. Krauss, Savvas C. Makrides, Victoria L.M. Herrera, Hou Xiang Xie, Hedy Adari, Una S. Ryan, Nelson Ruiz-Opazo | |||
| Spotting a killer's target in autoimmnue diabetes.(News & Views) | Health | Christophe Benoist, Diane Mathis | |||
| Stem cell politics, ethics and medical progress.(Commentary) | Health | Arthur L. Caplan, George J. Annas, Sherman Elias | |||
| Strategies used by human immunodeficiency virus that allow persistent viral replication. | Health | Ronald C. Desrosiers | |||
| Student drop-outs cause university ranking fears.(Statistical Data Included) | Health | Rada Rouse | |||
| Substitutes for success.(News & Views) | Health | Morris A. Blajchman | |||
| (super)1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis.(New Technology) | Health | Seppo Yla-Herttuala, Juhana M. Hakumaki, Harish Poptani, Anu-Maaria Sandmair, Risto A. Kauppinen | |||
| Taking more interest in conflict.(Editorial) | Health | Adrian J. Ivinson | |||
| Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation. | Health | Robert D. Rosenberg, Paul S. Frenette, Denisa D. Wagner, Eva Csizmadia, David L. Beeler, Helen Rayburn, Simon C. Robson, Keiichi Enjyoji, Jean Sevigny, Yuan Lin, Patricia D. Christie, Jan Schulte am Esch II, Masato Imai, Jay M. Edelberg, Miroslaw Lech | |||
| Targeting AIDS-Kaposi's sarcoma.(Statistical Data Included) | Health | Enrique A. Mesri | |||
| T cells are just dying to accept grafts.(News & Views) | Health | Douglas R. Green, Thomas A. Ferguson | |||
| T-cell stimulation: an abundance of B7s.(News & Views) | Health | Abul K. Abbas, Arlene H. Sharpe | |||
| Telomeres: has cancer's Achilles' heel been exposed?(News & Views) | Health | Victoria Lundblad, Louis A. Zumstein | |||
| Tetrameric HLA class I-minor histocompatibility antigen peptide complexes demonstrate minor histocompatibility antigen-specific cytotoxic T lymphocytes in patients with graft-versus-host disease.(Statistical Data Included) | Health | J.H. Frederik Falkenburg, Els Goulmy, Paul Moss, Tuna Mutis, Geraldine Gillespie, Elen Schrama | |||
| The challenge of private biomedical research funding in Italy.(Commentary)(Statistical Data Included) | Health | Claudio Bordignon | |||
| The death and resurrection of tuberculosis.(DNA vaccines)(News & Views) | Health | John D. McKinney, Barry R. Bloom | |||
| The effect of leptin on Lep expression is tissue-specific and nutritionally regulated. | Health | Nir Barzilai, Luciano Rossetti, Rong Liu, Jiali Wang, LiSen Liu, Rahena Chowdhury, Jianzhen Tan | |||
| The functional relevance of passenger leukocytes and microchimerism for heart allograft acceptance in the rat. | Health | Rainer Fischer, Saiho Ko, Andrea Deiwick, Mark D. Jager, Astrid Dinkel, Frank Rohde, Tung-Yu Tsui, Karl L. Rittmann, Kurt Wonigeit, Hans J. Schlitt | |||
| The great escape -- AIDS viruses and immune control.(News & Views) | Health | Bruce D. Walker, Philip J.R. Goulder | |||
| The great escape: is immune evasion required for tumor progression?(News & Views) | Health | Andreas Strasser, Andreas Villunger | |||
| The intrinsic factor-vitamin B(sub.12) receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein. | Health | John Fyfe, Christian Jacobsen, Maria Aminoff, Renata Kozyraki, Mette Kristiansen, Christian Gerdes, Shiying Cui, Erik Ilso Christensen, Albert De La Chapelle, Ralf Krahe, Pierre J. Verroust, Soren K. Moestrup | |||
| The matrix delivers.(includes related article on spinal cord regeneration) | Health | D.A. Lauffenburger, D.V. Schaffer | |||
| The NOD mouse model of type 1 diabetes: As good as it gets?(non-obese diabetic) | Health | Mark A. Atkinson, Edward H. Leiter | |||
| The pandemic of antibiotic resistance.(News and Views)(Statistical Data Included) | Health | Roy M. Anderson | |||
| The physiological response to cardiovascular `orphan' G protein-coupled receptor agonists.(News & Views) | Health | Joshua M. Hare, Jonathan S. Stamler, David A. Kass | |||
| The presence of ancient human T-cell lymphotropic virus type I provirus DNA in an Andean mummy. | Health | Shunro Sonoda, Kazuo Tajima, Satoshi Horai, Toshinobu Fujiyoshi, Shinji Yashiki, Hong-Chuan Li, Hong Lou, Luis Cartier, Lautaro Nunez, Ivan Munoz | |||
| The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis. | Health | B.S. Qiu, B.A. Vallance, P.A. Blennerhassett, S.M. Collins | |||
| The TRAIL to selective tumor death.(News and Views)(TRAIL: TNF-Related Apoptosis-Inducing Ligand)(TNF: tumor necrotizing factor)(Statistical Data Included) | Health | Jurg Tschopp, Lars E. French | |||
| The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's `two-hit' hypothesis. | Health | Ian Talbot, Mohammad Ilyas, Andrew Rowan, Robin Phillips, Victoria Johnson, Susan Clark, Walter Bodmer, Ian Tomlinson, Hanan Lamlum, Jennie Bell, Ian Frayling, Jason Efstathiou, Kevin Pack, Stewart Payne, Rebecca Roylance, Patricia Gorman, Denise Sheer, Kay Neale | |||
| The Wellcome Trust: leadership and partnership in biomedical research.(Commentary) | Health | Michael Dexter | |||
| Thymosin beta 4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoids. | Health | A.J. Lawrence, R.D. Stevenson, I.B. McInnes, J.D. Young, A.G. MacLean, B.P. Leung, B. Canas, D.J.C. Pappin | |||
| Tissue-specific consequences of the anti-adenoviral immune response: implications for cardiac transplants. | Health | Laurence A. Turka, Sherri Y. Chan, Kewang Li, Joseph R. Piccotti, Marisa C. Louie, Thomas A. Judge, Ernst J. Eichwald, D. Keith Bishop | |||
| Tobacco control -- drawing breath.(Editorial) | Health | ||||
| Tobacco money and medical research.(Editorial)(Statistical Data Included) | Health | ||||
| Tobacco -- the growing epidemic.(News & Views) | Health | Richard Peto, Jillian Boreham, Zheng-Ming Chen | |||
| Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. | Health | Ruth R. French, H.T. Claude Chan, Alison L. Tutt, Martin J. Glennie | |||
| Transmitochondrial mice carrying resistance to chloramphenicol on mitochondrial DNA: developing the first mouse model of mitochondrial DNA disease. | Health | David Barlow, David R. Marchington, Joanna Poulton | |||
| Transplantation tolerance -- where do we stand?(Review) | Health | Herman Waldmann | |||
| Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. | Health | Dennis W. Choi, David I. Gottlieb, John W. McDonald, Xiao-Zhong Liu, Yun Qu, Su Liu, Shannon K. Mickey, Dorothy Turetsky | |||
| Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. | Health | Allan D. Kirk, David M. Harlan, Linda C. Burkly, D. Scott Batty, Roxanne E. Baumgartner, Justin D. Berning, Kelvin Buchanan, John H. Fechner Jr., Rhonda L. Germond, Robert L. Kampen, Noelle B. Patterson, S. John Swanson, Douglas K. Tadaki, Christopher N. TenHoor, Leonard White, Stuart J. Knechtle | |||
| Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor beta1. | Health | Rakesh K. Jain, Dai Fukumura, Yves Boucher, Gerald A. Soff, Takeshi Gohongi, Chae-Ok Yun, Carolyn Compton, Takeshi Todoroki | |||
| Turning on tumors to study cancer progression.(News & Views) | Health | Anton Berns | |||
| Uganda gives lessons in stemming the AIDS epidemic.(Editorial) | Health | ||||
| Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice.(basal cell carcinoma) | Health | Matthew P. Scott, Philip E. LeBoit, Michelle Aszterbaum, John Epstein, Anthony Oro, Vanja Douglas, Ervin H. Epstein Jr. | |||
| Universities offer animal rights courses.(News) | Health | Tinker Ready | |||
| Unraveling hepatitis B virus infection of mice and men (and woodchucks and ducks).(News & Views) | Health | Stephen Menne, Bud C. Tennant | |||
| Unraveling the strands of HIVs web.(News & Views) | Health | Giuseppe Pantaleo | |||
| Upregulation of RGS7 may contribute to tumor necrosis factor-induced changes in central nervous function. | Health | Emily Kim, Gerd Walz, Thomas Benzing, Ralf Brandes, Lorenz Sellin, Bernhard Schermer, Stewart Lecker | |||
| US guidelines on xenotransplantation.(Editorial) | Health | ||||
| US to make research marijuana more accessible. | Health | ||||
| Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice. | Health | Anil B. Mukherjee, Zhongjian Zhang, Feng Zheng, Gopal C. Kundu, Jerrold Ward, Francesco DeMayo | |||
| VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. | Health | Napoleone Ferrara, Thiennu H. Vu, Zena Werb, Joe Kowalski, Hans-Peter Gerber, Anne M. Ryan | |||
| Victory at C. | Health | Peter A. Friedman, Mark L. Zeidle | |||
| Viral receptors and vector purification: new approaches for generating clinical-grade reagents.(New Technology) | Health | Richard Jude Samulski, Candace Summerford | |||
| Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef. | Health | Todd M. Allen, David H. O'Connor, John L. Dzuris, Austin L. Hughes, Alessandro Sette, David I. Watkins, Thorsten Vogel, David T. Evans, John Sidney, C. David Pauza, Peicheng Jing, Jack Da Silva, Helen Horton, John E. Venham, Richard A. Rudersdorf, Ronald E. Bontrop, Robert DeMars | |||
| What are the prospects for a universal influenza vaccine?(News & Views) | Health | Edwin D. Kilbourne | |||
| Who's that lady?(army bases in England and France may have spread influenza in 1914-1918)(News & Views) | Health | J.S. Oxford, A. Sefton, R. Jackson, N.P.A.S. Johnson, R.S. Daniels | |||
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