Cell 2006 - Abstracts
| Cell 2006 | |||||
| Title | Subject | Authors | |||
|---|---|---|---|---|---|
| A bivalent chromatin structure marks key developmental genes in embryonic stem cells. | Biological sciences | Eric S. Lander, Stuart L. Schreiber, Michael Kamal, Bradley E. Bernstein, Xiaohui Xie, Alexandre Wagschal, Tarjel S Mikkeisen, Dana J Huebert, James Cuff, Ben Fry, Alex Meissner, Marius Wernig, Kathrin Plath, Rudolf Jaenish, Robert Fell | |||
| A C. elegans model of nicotine-dependent behavior: Regulation by TRP-family channels.(Report) | Biological sciences | Paul W. Sternberg, Alex Ward, Wei Li, X.Z. Shawn Xu, Zhaoyang Feng, Beverly J. Piggott, Erin R. Larkspur | |||
| A checkpoint protein that scans the chromosome for damage at the start of sporulation in Bacillus subtilis. | Biological sciences | Michal Bejerano-Sagie, Yaara Oppenhimer-Shaanan, Idit Berlatzky, Alex Rouvinski, Meyerovich, Mor; Ben-Yehuda, Sigal | |||
| A CK2-dependent mechanism for degradation of the PML tumor suppressor. | Biological sciences | Pier Paolo Pandolfi, Hediye Erdjument-Bromage, Pier Paolo Scaglioni, Julie Teruya-Feldstein, Thomas M. Yung, Lu Fan Cai, Andrew J. Kaufman, Bhuvanesh Singh | |||
| A class of membrane proteins shaping the tubular endoplasmic reticulum.(saccharomyces cerevisiae) | Biological sciences | Tom A. Rapoport, Gia K. Voeltz, Yoko Shibata, William A. Prinz, Julia M. Rist | |||
| A colorful model of the circadian clock. | Biological sciences | Steven M. Repport | |||
| A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis. | Biological sciences | Josep Rizo, Thomas C. Sudhof, Anton Maximov, Jiong Tang, Ok-Ho Shin | |||
| A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. | Biological sciences | Lehtinen, Maria K.; Zengqiang Yuan, Boag, Peter R.; Yue Yang, Villen, Judit; Becker, Esther B.E., DiBacco, Sara; Iglesia, Nuria de la, Gygi, Steven; Blackwell, T. Keith; Bonni, Azad | |||
| Activation of glucosidase via stress-induced polymerization rapidly increases active pools of abscisic acid. | Biological sciences | Kwang Hee Lee, Hai Lan Piao, Iidoo Hwang, June M. Kwak, In-Jung Lee, Inhwan Hwang | |||
| Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. | Biological sciences | Janna E. Slessareva, Sheri M. Routt, Brenda Temple, Vytas A. Bankaitis, Henrik G. Dohlman | |||
| A dedicated Wnt secretion factor. | Biological sciences | Roel Nusse, Wendy Ching | |||
| A DNA integrity network in the yeast Saccharomyces cerevisiae. | Biological sciences | Jef D. Boeke, Joel S. Bader, Xuewen Pan, Ping Ye, Daniel S. Yuan, Xiaoling Wang | |||
| A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q. | Biological sciences | Ralph M. Steinman, Rebecca M. Lynch, Young-Sun Kang, Yoonkyung Do, Hae-Kyung Lee, Sung Ho Park, Cheolho Cheong, Jutta M. Loeffler, Chae Gyu Park | |||
| A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator. | Biological sciences | Lucy Shapiro, Patrick T. McGrath, Antonio A. Iniesta, Kathleen R. Ryan, Harley H. McAdams | |||
| A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.(Report) | Biological sciences | Kenneth D. Poss, Richard W. Roberts, Alexandra Lepilina, Ashley N. Coon, Jennifer E. Holdway, Kazu Kikuchi, C. Geoffrey Burns | |||
| A fetching model organism. | Biological sciences | Jasper Rine, Mark W. Neff | |||
| A gene-centered C. elegans protein-DNA interaction network. | Biological sciences | Deplancek, Bart; Mukhopadhyay, Arnab, Wanyuan Ao; Elewa, Ahmed; Grove, Christian A., Martinez, Natalia J.;. Sequerra, Reynaldo; Doucette-Stamm, Lynn, Reece-Hoyes, John S.; Hope, Ian A., Tissenbaum, Heidi A.; Mango, Susan E.; Walhout, Albertha J.M. | |||
| A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. | Biological sciences | Hiroshi Nojima, Reuven Agami, Carlos le Sage, Eitan Zlotorynski, Mathijs P. Voorhoeve, Mariette Schrier, Ad J.M. Gillis, Hans Stoop, Remco Nagel, Ying-Poi Liu, Josyanne van Duijse, Jamo Drost, Alexander Griekspoor, Yabuta Norikazu, Gabriella De Vita, Leendert H.J Looljenga | |||
| A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. | Biological sciences | Nevan J. Krogan, Andrew Emili, Jack F. Greenblatt, Laura Maringele, David Lydall, Sarah Galicia, Michael Downey, Daniel Durocher, Rebecca Houlsworth, Adrienne Rollie, Marc Brehme, Sandrine Guillard, Melanie Partington, Mikhajlo K. Zubko, Lea Harrington | |||
| A global map of p53 transcription-factor binding sites in the human genome. | Biological sciences | Vladimir A. Kuznetsov, Qiang Wu, Edison T. Liu, Zhiping Weng, Chia-Lin Wei, Vinsensius B. Vega, Kuo Ping Chiu, Patrick Ng, Tao Zhang, Atif Shahab, YuTao Fu, How Choong Yong, JianJun Liu, Xiao Dong Zhao, Joon-Lin Chew, Yen Ling Lee, Wing-Kin Sung, Lance D. Miller, Bing Lim, Qiang Yu, Huck-Hui Ng, Yijun Ruan | |||
| A greedy promoter controls malarial var-iations. | Biological sciences | Artur Scherf | |||
| A hybrid vector for ligand-directed tumor targeting and molecular imaging. | Biological sciences | Yan Sun, Roberto Rangel, Renata Pasqualini, Amin Hajitou, Martin Trepal, Catherine A. Moya, Karim Zaoui, Lilley, Caroline E.; Arap, Wadih, Suren Soghomonyan, Bradley H. Restel, Christopher von Kalle | |||
| A kinase gets caspases into shape. | Biological sciences | Denise J. Montell | |||
| A landmark protein essential for establishing and perpetuating the polarity of a bacterial cell. | Biological sciences | Christine Jacobs-Wagner, Hubert Lam, Whitman B. Schofield | |||
| A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. | Biological sciences | Eric S. Lander, William C. Hahn, David M. Sabatini, Sheila A. Stewart, Xiaoping Yang, Jason Moffat, Brent R. Stockwell, Bruno Piqani, Dorre A. Grueneberg, So Young Kim, Angela M. Kloepfer, Gregory Hinkle, Thomas M. Eisenhaure, Blao Luo, Jennifer K. Grenler, Anne E. Carpenter, Shi Yin Foo, Nir Hacohen, David E. Root | |||
| A long-distance relationship between RNAi and Polycomb. | Biological sciences | Victor G. Corces, Ellssa P. Lel | |||
| A lost generation.(National Institutes of Health funding policies for research) | Biological sciences | Robert A. Weinberg | |||
| [alpha]3Na[.sup.+]/K[.sup.+]-ATPase is a neuronal receptor for agrin. | Biological sciences | Lutz G.W. Hilgenberg, Halling Su, Hualyu Gu, Diane K. O'Dowd, Martin A. Smith | |||
| A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation. | Biological sciences | Jonathan S. Weissman, Vladimir Denic, Erin M. Quan | |||
| A mammalian organelle map by protein correlation profiling. | Biological sciences | Mathias Mann, Yong Zhang, Leonard J. Foster, Carmen L. de Hoong, Yanling Zhang, Xiaohul Xie, K. Mootha Vamsi | |||
| A mitotic role for BRCA1/BARD1 in tumor suppression?.(Report) | Biological sciences | Paul R. Clarke, Helen S. Sanderson | |||
| A molecular beacon defines bacterial cell asymmetry. | Biological sciences | Melanie L. Lawier, Brun Yves V. | |||
| A molecular mousetrap determines polarity of termination of DNA replication in E. coli. | Biological sciences | Cameron Neylon, Thomas M. Hill, Nicholas E. Dixon, Mark D. Mulcair, Patrick M. Schaeffer, Aaron J. Oakley, Hannah F. Cross | |||
| An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. | Biological sciences | John Kuriyan, Philip A. Cole, Xuewu Zhang, Jodi Gureasko, Kui Shen | |||
| Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. | Biological sciences | Yanxia Bei, Ka Ming Pang, Martin J. Simard | |||
| An ARGONAUTE4-containing nuclear processing center colocalized with Cajal bodies in Arabidopsis thaliana. | Biological sciences | Ian R. Henderson, Olga Pontes, Craig S. Pikaard, Thierry Lagrange, Carey Fei Li, Steven E. Jacobsen, Mahmoud El-Shami, Yana N. Bernatavichute, Simon W.-L. Chan | |||
| Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. | Biological sciences | Michael Downes, Ronald M. Evans, David J. Mangelsdorf, Angie L. Bookout, Yangsik Jeong | |||
| A neuronal identity code for the odorant receptor-specific and activity-dependent axon sorting.(Report) | Biological sciences | Shou Serizawa, Kazunari Miyamichi, Haruki Takeuchi, Yuya Yamagishi, Misao Susuki, Hitoshi Sakano | |||
| A new function for p53 ubiquitination. | Biological sciences | Ze'ev Ronai, Yuko Hirano | |||
| A novel role for high-mobility group A proteins in cellular senescence and heterochromatin formation. | Biological sciences | Scott W. Lowe, Masashi Narita, Sabrina Nunez, Masako Narita, Stephen A. Hearn, Michael P. Myers, Valery Krizhanovsky, Agustin Chicas | |||
| An RNA sensor for intracellular Mg(super 2+). | Biological sciences | Eduardo A. Groisman, Michael J. Cromie, Yixin Shi, Tammy Latifl | |||
| An SDF-1 trap for myeloid cells stimulates angiogenesis. | Biological sciences | Peter Carmeliet, Aernout Luttun, Carmen Ruiz de Almodovar | |||
| Anti-immunology: Evasion of the host immune system by bacterial and viral pathogens. | Biological sciences | B. Brett Finlay, Grant McFadden | |||
| Antisense transcription controls cell fate in Saccharomyces cerevisiae. | Biological sciences | Paula L. Grisafi, Timothy Galitski | |||
| A one-sided view of kinetochore attachment in meiosis. | Biological sciences | Yoshinori Watanabe | |||
| A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes. | Biological sciences | Thomson, Andrew M.; Bing Lim, Miranda, Kevin C.; Tien Huynh, Isidore Rigoutsos | |||
| A pericellular collagenase directs the 3-dimensional development of white adipose tissue. | Biological sciences | Alan R. Saltiel, Stephen J. Weiss, Kevin B. Hotary, Tae-Hwa Chun, Farideh Sabeh, Edward D. Allen | |||
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. | Biological sciences | Knight, Zachery A.; Gonzalez, Beatriz, Feldman, Morri E.; Zunder, Eli R., Goldenberg, David D.; Williams, Olusegun, Loewith, Robbie; Stokoe, David; Balla, Andras; Toth, Balazs, Balla, Toth; Weiss, William A.; Williams, Roger L.; Shokat, Kevan M. | |||
| A phosphatase controls the fate of receptor-regulated Smads. | Biological sciences | Xiao-Fan Wang, Stephen H. Schilling, Michael B. Datto | |||
| A protein kinase, interacting with two calcineurin B-like proteins, regulates [K.sup.} transporter AKT1 in Arabidopsis. | Biological sciences | Jiang Xu, Yi Wang, Hao-Dong Li, Li-Qing Chen, Li-Li Liu, Liu He, Wei-Hua Wu | |||
| A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. | Biological sciences | Janghoo Lim; Tong Hao, Chad Shaw; Patel, Akash J., Szabo, Gabor; Rual, Jean-Francois, Fisk, C. Joseph; Ning Li; Smolyar, Alex; Hill, David E., Barabasi, Alex-Laszlo.; Vidal, Marc; Zoghbi, Hida Y. | |||
| A quick release mechanism for abscisic acid. | Biological sciences | Julian I. Schroeder, Eiji Nambara | |||
| A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules. | Biological sciences | Laura A. Banaszynski, Lystranne A. Maynard-Smith, Ling-chun Chen, Thomas J. Wandless | |||
| Architectural design and the collaborative research environment. | Biological sciences | Roger N. Goldstein | |||
| A receptor-modifying deamidase in complex with a signaling phosphatase reveals reciprocal regulation. | Biological sciences | George W. Ordal, Brian R. Crane, Xingjuan Chao, Travis J. Muff, Sang-Youn Park, Sheng Zhang, Abiola M. Pollard, Alexandrine M. Bilwes | |||
| Are mouse telomeres going to Pot? | Biological sciences | Peter Baumann | |||
| A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. | Biological sciences | Andrei Starostine, Clark D. Wells, James P. Fawcett, Andreas Traweger, Elder, Kelly; Colwill, Karen, Sarang Kulkarni, Yojiro Yamanaka, Virag, Cristina; Pawson, Tony, Goudreault, Marilyn; Lim, Caesar | |||
| A role for p130Cas in mechanotransduction.(Report) | Biological sciences | Benjamin Geiger | |||
| A role for TFIIIC transcription factor complex in genome organization. | Biological sciences | Shiv I.S. Grewal, Hugh P. Cam, Ken-ichi Noma, Richard J. Maraia | |||
| A role for the deubiquinating enzyme USP28 in control of the DNA-damage response. | Biological sciences | Stephen J. Elledge, Tak W. Mak, Dong Zhang, Kathrin Zaugg | |||
| Arrays of hope.(MicroArray Quality Control (MAQC) project by US Food and Drug Administration) | Biological sciences | Evelyn Strauss | |||
| A segmentation gene in Tribolium produces a polycistronic mRNA that codes for multiple conserved peptides. | Biological sciences | Diethard Tautz, Joel Savard, Henrique Marques-Souza, Manuel Aranda | |||
| Astrocytes put down the broom and pick up the baton. | Biological sciences | Jeffrey S. Diamond | |||
| A super highway to virus infection. | Biological sciences | Urs F. Greber, Michael Way | |||
| Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. | Biological sciences | Karl Mechtler, Juergen A. Knoblich, Joerg Betschinger | |||
| A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin. | Biological sciences | Richard Losick, Craig D. Ellermeier, Errett C. Hobbs, Jose E. Gonzalez-Pastor | |||
| A tiny helper lightens the maternal load.(maternal mRNAs at the mid-blastula transition of early animal embryogenesis ) | Biological sciences | Detlef Weigel, Elisa Izaurralde | |||
| A transcriptional logic for nuclear reprogramming. | Biological sciences | Kevin Eggan, Kit T. Rodolfa | |||
| A two-hit trigger for siRNA biogenesis in plants.(Report) | Biological sciences | David P. Bartel, Michael J. Axtell, Calvin Jan, Ramya Rajagopalan | |||
| Avant garde fatty acid synthesis by trypanosomes. | Biological sciences | John E. Cronan | |||
| Bacterial adhesion and entry into host cells. | Biological sciences | P. Cossart, J. Pizarro-Cerda | |||
| Bacterial birth scar proteins mark future flagellum assembly site. | Biological sciences | Edgar Huitema, Sean Pritchard, David Matteson, SunishKumar Radhakrishnan, Patrick H. Viollier | |||
| Bacterial genomics and pathogen evolution. | Biological sciences | R. Seshadri, D.M. Raskin, S.U. Pukatzki, J.J. Mekalanos | |||
| Bacterial glycans: Key mediators of diverse host immune responses. | Biological sciences | Dennis L. Kasper, Laurie E. Cornstock | |||
| Bacterially speaking. | Biological sciences | Richard Losick, Bonnie L. Bassier | |||
| Bent out of shape: RNA unwinding by the DEAD-box helicase Vasa. | Biological sciences | Paul Lasko, Patrick Linder | |||
| Beta4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. | Biological sciences | William J. Muller, Giorgio Inghirami, Yuliya Pylayeva, Filippo G. Giancotti, Wenjun Guo, Angela Pepe, Toshiaki Yoshioka | |||
| Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. | Biological sciences | Elaine Fuchs, Alexander Tarakhovsky, Donal O'Carroll, Valerie Horsley, Yasuhide Ohinata, Michel Nussenzweig, Mitinori Saitou, Tetyana Obukhanych, Reuben Tooze | |||
| Blurring cis and trans in gene regulation. | Biological sciences | Rudolf Grosschedl, Fabio Savarese | |||
| Bone formation: The nuclear matrix reloade. | Biological sciences | Robb Krumlauf, Debra L. Ellies | |||
| Boning up on ephrin signaling. | Biological sciences | Gregory R. Mundy, Florent Elefteriou | |||
| Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles. | Biological sciences | Anne Ephrussi, Matthias W. Hentze, Marina Chekulaeva | |||
| Building bridges to the corte. | Biological sciences | Gord Fishell, Carina Hanashima, Zoltan Moinar | |||
| Cafe Scientifique - deja vu. | Biological sciences | Duncan Dallas | |||
| Calcium signaling networks channel plant [K.sup.} uptake. | Biological sciences | Rainer Hedrich, Jorg Kudla | |||
| CAMTA in cardiac hypertrophy. | Biological sciences | Robert J. Schwartz, Michael D. Schneider | |||
| Cancer metastasis: Building a framework. | Biological sciences | Joan Massague, Gaorav P. Gupta | |||
| Cargo regulates clathrin-coated pit dynamics. | Biological sciences | Manojkumar A. Puthenveedu, Mark von Zastrow | |||
| Cargo takes control of endocytosis. | Biological sciences | Volker Haucke | |||
| Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. | Biological sciences | Jurg Tschopp, F. Gisou van der Goot, Laure Gurcel, Laurence Abrami, Stephen Girardin | |||
| Caspase-1 builds a new barrier to infection. | Biological sciences | Maya Saleh | |||
| Cecile Pickart 1954-2006.(was successful in shaping the ubiquitin field)(Obituary) | Biological sciences | Keith D. Wilkinson, D. Finley | |||
| C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span. | Biological sciences | Leonard Guarente, H. Robert Horvitz, Ala Berdichevsky, Mohan Viswanathan | |||
| Cell shape in proliferating epithelia: A multifaceted problem. | Biological sciences | Jeffrey D. Axelrod | |||
| Cellular conference call: External feedback affects cell-fate decisions. | Biological sciences | Alexander Loawer, Gallt Lahav | |||
| Cernunnos, a novelnonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly. | Biological sciences | Patrick Revy, Ozden Sanal, Alain Fischer, Anne Durandy, Jean-Pierre de Villartay, Deitke Buck, Laurent Malivert, Chasseval, Regina de, Anne Barraud, Marie-Claude Fondaneche, Alessandro Piebani, Jean-Louis Stephan, Markus Hufnagel, Francoise Deist | |||
| CFTR: New members join the fold.(cystic fibrosis transmembrane conductance regulator) | Biological sciences | William R. Skach | |||
| Chemical technologies for probing glycans. | Biological sciences | Jennifer A. Prescher, Carolyn R. Bertozzi | |||
| Circadian regulator CLOCK is a histone acetyltransferase. | Biological sciences | Paolo Sassone-Corsi, Masao Doi, Jun Hirayama | |||
| Circadian transcription: Passing the HAT to CLOCK. | Biological sciences | Wangjie Yu, Paul E. Hardin | |||
| Circannual control of hibernation by HP complex in the brain. | Biological sciences | Noriaki Kondo, Tsuneo Sekjima, Jun Kondo, Nobuhiko Takamatsu, Kazuo Tohya, Takashi Ohtsu | |||
| CK2 and PML: Regulating the regulator. | Biological sciences | Valerie Lallemand-Breitenbach, Hugues de The | |||
| Clearing a path through the patent ticket. | Biological sciences | Chris Holman | |||
| Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin. | Biological sciences | Graham, Rona K.; Yu Deng; Slow, Elizabeth J., Bissada, Nagat; Ge Lu; Pearson, Jacqueline; Shehadeh, Jacqueline, Bertram, Lisa; Murphy, Zoe; Warby, Simon C.; Doty, Crystal N., Raymond, Lynn A.; Nicholson, Donald W.; Hayden, Michael R.; Haigh, Brendan | |||
| Clonal origin and evolution of a transmissible cancer. | Biological sciences | Robin A. Weiss, Claudio Murgia, Jonathan K. Pritchard, Su Yeon Kim, Ariberto Fassati | |||
| Closing the GAP between polarity and vesicle transport. | Biological sciences | Ian G. Macara, Anne Spang | |||
| Coding of odors by a receptor repertoire. | Biological sciences | Elissa A. Hallem, John R. Carlson | |||
| Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. | Biological sciences | Lynda Chin, William C. Hahn, Stephan N. Wagner, Carlos Cordon-Cardo, Lyn M. Duncan, Cameron Brennan, Bin Feng, Scott R. Granter, Minjung Kim, Joseph D. Gans, Cristina Nogueira, Audrey Wang, Ji-Hye Paik, Thomas J. Flotte | |||
| Connecting cancer to the asymmetric division of stem cells. | Biological sciences | Cayetano Gonzalez, Andreas Wodarz | |||
| Control of developmental regulators by Polycomb in human embryonic stem cells. | Biological sciences | Matthew G. Guenther, Richard A. Young, Douglas A. Melton, David P. Bartel, Thomas L. Volkert, David K. Gifford, Rudolf Jaenisch, Kuniya Abe, Nancy M. Hannett, Arie P. Otte, Jacob P. Zucker, Tong Ihn Lee, Megan F. Cole, Sarah E. Johnstone, Roshan M. Kumar, Heather L. Murray, Richard G. Jenner, George W. Bell, Stuart S. Levine, Laurie Boyer A., Brett Chevalier, Kyo-Ichi Isono, Haruhiko Koseki, Fuchikami Takuya, Bingbing Yuan, Elizabeth Herbolshelmer, Kaiming Sun, Duncan T. Odom | |||
| Control of the assembly of ATP- and ADP-Actin by formins and profilin. | Biological sciences | Henry N. Higgs, Thomas D. Pollard, David R. Kovar, Elizabeth S. Harris, Rachel Mahaffy | |||
| Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload. | Biological sciences | Michael G. Katze, David Ron, Seiichi Oyadomari, Heather P. Harding, Jennifer L. Garrison, Jack Taunton, Hanna Harant, Chi Yun, Edward A. Fisher, Nicola Kreglinger, Gert Kreibich, Miho Oyadomari, Alan G. Goodman | |||
| Creationism and evolution: It's the American way. | Biological sciences | Eugenie C. Scott | |||
| CRIg: A macrophage Complement Receptor required for phagocytosis of circulating pathogens. | Biological sciences | Suzie J. Scales, Nico Ghilardi, Karim Y. Helmy, Kenneth J. Katschke Jr., Nick N. Gorgani, Noelyn M. Kljavin, Lauri Diehl, J. Michael Elliot, Menno van Lookeren Campagne | |||
| Crossover homeostasis in yeast meiosis. | Biological sciences | Scott Keeney, Neil Hunter, Robert L. Diaz, Emmanuelle Martini | |||
| Cross-species oncogenomics in cancer gene identification. | Biological sciences | Anton Berns, Daniel Peeper | |||
| CRTAP is required for prolyl 3-hydroxylation and mutations cause recessive osteogenesis imperfecta.(Cartilage Association Protein) | Biological sciences | Ulrike Schwarze, Peter H. Byers, Hans Peter Bachinger, John Hicks, Brendan Lee, Brendan F. Boyce, Yuqing Chen, Roy Morello, Terry K. Bertin, David R. Eyre, Zhenqiang Yao, Massimiliano Monticone, Patrizio Castagnola, Frank Rauch, Francis H. Glorieux, Janice Vranka, James M. Pace, Mary Ann Weis, Russell J. Fernandes | |||
| Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN.(cryo-electron microscopy) | Biological sciences | Michael G. Rossmann, Wayne A. Hendrickson, Paul R. Chipman, Ying Zhang, Elena Pokidysheva, Anthony J. Battisti, Carol M. Bator-Kelly, Chuan Xiao, G. Glenn Gregorio, RIchard J. Kuhn | |||
| Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements. | Biological sciences | Harry F. Noller, Andrei Korostelev, Sergei Trakhanov, Martin Laurberg | |||
| Crystal structure of the catalytic [alpha] subunit of E. coli replicative DNA Polymerase lll. | Biological sciences | Meindert H. Lamers, Mike O'Donnell, John Kuriyan, Roxana E. Georgescu, Sang-Gyu Lee | |||
| Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. | Biological sciences | Jeffrey J. Wilson, Rhett A. Kovall | |||
| Crystal structure of the DsbB-DsbA complex reveals a mechanism of disulfide bond generation. | Biological sciences | Satoshi Murakami, Kenji Inaba, Kengo Okada | |||
| Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin. | Biological sciences | Andrea Musacchio, Pier Paolo Di Fiore, Stefano Confalonieri, Simona Polo, Lorenza Penengo, Marina Mapelli, Adrea G. Murachelli, Laura Magri, Thomas R. Schneider | |||
| Crystal structures of a ligand-free MthK gating ring: Insights into the ligand gating mechanism of [K.sup.+] channels. | Biological sciences | Liping Chen, Sheng Ye, Youxing Jiang | |||
| Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism. | Biological sciences | Maria A. Schumacher, Elham Karamooz, Alena Zikova, Lukas Trantirek, Julius Lukes | |||
| Cyclin-dependent kinase directly regulates initiation of meiotic recombination. | Biological sciences | Scott Keeney, Kiersten A. Henderson, Kehkooi Kee, Shohreh Maleki, Paul A. Santini | |||
| Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-(kappa)B signaling. | Biological sciences | Reinhard Fassler, Alexander Pfeifer, Ramin Massoumi, Katarzyna Chmielarska, Katharina Hennecke | |||
| CYLD in ubiquitin signaling and tumor pathogenesis. | Biological sciences | Ivan Dikic, Fumiyo Ikeda | |||
| Deletion of DDB1 in mouse brain and Lens leads to p53-dependent elimination of proliferating cells.(Report) | Biological sciences | Stephen P. Goff, Pengbo Zhou, Yong Chang, Jianxuan Zhang, Sally A. Nicholas, Jayson Bastien, Baojie Li | |||
| DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation.(arabidopsis polycomb group gene) | Biological sciences | Robert L. Fischer, Tzung-Fu Hsieh, Mary Gehring, Jin Hoe Huh, Jon Penterman, Yeonhee Choi, John J. Harada, Robert B. Goldberg | |||
| Dendritic protein synthesis, synaptic plasticity, and memory. | Biological sciences | Erin M. Schuman, Michael A. Sutton | |||
| DEP-domain-mediated regulation of GPCR signaling responses. | Biological sciences | Jeremy Thorner, Douglas P. Gladue, Daniel R. Ballon, Paul L. Flanary, James B. Konopka | |||
| Descrambling Dscam diversity. | Biological sciences | Alex L. Kolodkin, Rajnish Bharadwaj | |||
| Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation. | Biological sciences | Daniel Finley, Steven P. Gygi, Randall W. King, John Hanna, Nathaniel A. Hathaway, Yoshiko Tone, Bernat Crosas, Suzanne Elsasser, Donald S. Kirkpatrick, David S. Leggett | |||
| Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses. | Biological sciences | Joanne Chory, Jennifer L. Nemhauser, Fangxin Hong | |||
| DisA, a busy bee that monitors chromosome integrity. | Biological sciences | Erik Boye | |||
| Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms. | Biological sciences | Ulrike Heberlein, Roland J. Bainton, Adrian Rothenfluh, Robert J. Threlkeld, Amy W. Lasek, Linus T.-Y. Tsai | |||
| Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. | Biological sciences | Tom A. Rapoport, Pedro Carvalho, Veit Goder | |||
| DNA double-strand break repair: A relentless hunt uncovers new prey. | Biological sciences | David O. Ferguson, JoAnn M Sekiguchi | |||
| Downregulation of PP2[A.sup.Cdc55] phophatase by separase initiates mitotic exit in budding yeast. | Biological sciences | Frank Uhlmann, Ether Queralt, Bela Novak | |||
| DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.(Damage-regulated autophagy modulator) | Biological sciences | Kevin M. Ryan, Paul Smith, Diane Crighton, Simon Wilkinson, Jim O'Prey, Nelofer Syed, Paul R. Harrison, Milena Gasco, Omella Garrone, Tim Crook | |||
| Driving actin dynamics under the influence of alcohol. | Biological sciences | Linda Van Aelst, Raffaella Sordella | |||
| Drosophila lKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs. | Biological sciences | Masayuki Miura, Masatomo Kobayashi, Erina Kuranaga, Hirotaka Kanuka, Ayako Tonoki, Kiwamu Takemoto, Takeyasu Tomioka, Shigeo Hayashi | |||
| Dynamic helix interactions in transmembrane signaling.(Report) | Biological sciences | Donald M. Engelman, Erin E. Matthews, Manuela Zoonens | |||
| Dynamic nuclear pore complexes: Life on the edge. | Biological sciences | Elizabeth J. Tran, Susan R. Wente | |||
| E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation. | Biological sciences | Laurent Le Cam, Laetitia K. Linares | |||
| Ecological and evolutionary forces shaping microbial diversity in the human intestine. | Biological sciences | Jeffrey I. Gordon, Ruth E. Ley, Daniel A. Peterson | |||
| EGF receptor activation: Push comes to shove.(epidermal growth factor receptor) | Biological sciences | Stevan R. Hubbard | |||
| Embryonic dorsal-ventral signaling: Secreted Frizzled-related proteins as inhibitors of Tolloid Proteinases. | Biological sciences | Bruno Reversade, Hojoon X. Lee, Andrea L. Ambrosio, E.M. De Robertis | |||
| Emerging and re-emerging infectious diseases: Influenza as a prototype of the host-pathogen balancing act. | Biological sciences | Anthony S. Fauci | |||
| Emerging patterns in complement-mediated pathogen recognition. | Biological sciences | Michael C. Carroll, Ramon Roozendaal | |||
| Emilin1 links TGF-beta maturation to blood pressure homeostasis. | Biological sciences | Gennaro Marino, Carmine Vecchione, Michelangelo Cordenonsi, Silvia Maretto, Stefano Piccolo, Giulio Selvetella, Angelo Maffei, Luca Zacchigna, Sandra Soligo, Maddalena Adorno, Alessandra Ferrari, Antonelia Notte, Sirioo Dupont, Cifelli Giuseppe, Carla Fabbro, Paola Braghetta, Russo Giovanni, Dino Volpin, Guiseppe Lembo, Giorgio M. Bressan, Alessandro Aretini, Claudio Colonese, Umberto Bettarini | |||
| Endocytosis conducts the cell signaling orchestra. | Biological sciences | Pier Paolo Di Fiore, Simona Polo | |||
| Endoplasmic reticulum stress activates cleavage of CREBH to induce a systematic inflammatory response.(caenorhabditis elegans) | Biological sciences | Randal J. Kaufman, Jun Wu, Kezhong Zhang, Xiahua Shen, Kenjiro Sakaki, Thomas Saunders, D. Thomas Rutkowski, Sung Hoon Back | |||
| EphB receptors coordinate migration and proliferation in the intestinal stem cell niche. | Biological sciences | Johan Holmberg, Genander, Maria; Halford, Michael M., Anneren, Cecilia; Sondell, Mariann, Chumley, Michael J.; Silvany, Robert E., Henkemeyer, Mark; Frisen, Jonas | |||
| Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. | Biological sciences | Ralf H. Adams, Per Lindblom, Shane S. Foo, Christopher J. Turner, Sussanne Adams, Amelia Compagni, Deborah Aubyn, Naoko Kogata, Moshe Shani, Daniel Zicha | |||
| ErbB2 makes beta4 integrin an accomplice in tumorigenesis. | Biological sciences | Senthil K. Muthuswamy | |||
| ER targeting signals: more than meets the eye?(Report) | Biological sciences | Stephen High, Eileithyia Swanton | |||
| ESCRT-I core and ESCRT-II glue domain structures reveal role glue in linking to ESCRT-I and membranes. | Biological sciences | Olga Perisic, Roger L. Williams, Yvonne Vallis, Halangling. Teo, David J. Gill, Ji. Sun, Dmitry B. Veprintsev, Scott.D. Emr | |||
| Evidence that loading of cohesin onto chromosomes involves opening of its SMC hinge.(Report) | Biological sciences | Kim Nasmyth, Stephan Gruber, Yuki Katou, Katsuhiko Shirahige, Wolfgang Helmhart, Prakash Arumugam, Daria Kuglitsch | |||
| Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast. | Biological sciences | David E. Williams, Timothy R. Hughes, Gregory S. Payne, Charles Boone, Brendan J. Frey, Charles Brenner, Brenda Andrews, Gordon Chua, Ainslie B. Parsons, Renee L. Brost, Richelle Sopko, Inmar E. Givoni, Andres Lopes, Christopher A. Gray, Justin Porter, Cheuk-Hei Ho, Jiyi Wang, Troy Ketela, Julie A. Brill, G. Esteban Fernandez, Todd C. Lorenz, Satoru Ishihara, Yoshikazu Ohya, Todd R. Graham, Raymond J. Andersen | |||
| Exploring transcriptional regulatory networks in the worm. | Biological sciences | Illes J. Farkas, Qasim K. Beg, Zoltan N. Oltvai | |||
| Fatty acid synthesis by elongases in trypanosomes. | Biological sciences | Soo Hee Lee, Jennifer L. Stephens, Kimberly S. Paul, Paul T. Englund | |||
| Flies without centrioles. | Biological sciences | Jordan W. Raff, C. Geoffrey Woods, Renata Basto, Joyce Lau, Tatiana Vinogradova, Alejandra Gardiol, Alexey Khodjakov | |||
| Flipping riboswitches. | Biological sciences | Evgeny Nudler | |||
| Follow your nose: Axon pathfinding in olfactory map formation.(Report) | Biological sciences | Yao Chen | |||
| Force sensing by mechanical extension of the Src family kinase substrate p130Cas.(Report) | Biological sciences | Michael P. Sheetz, Sakae Tanaka, Oksana Cherniavskaya, Benjamin J. Dubin-Thaler, Yasuhiro Sawada, Masako Tamada, Ryuichi Sakai | |||
| Forcing the third dimension. | Biological sciences | Nancy Boudreau, Valerie Weaver | |||
| Forespore engulfment mediated by a ratchet-like mechanism. | Biological sciences | Kit Pogliano, Dan H. Broder | |||
| FOXP3 and NFAT: Partners in tolerance. | Biological sciences | Ye Zhang, Alexander Y. Rudensky, Marc Gavin | |||
| FOXP3 controls regulatory T cell function through cooperation with NFAT. | Biological sciences | Markus Feuerer, Yongqing Wu, Madhuri Borde, Vigo Heissmeyer, Ariya D. Lapan, Stroud, James C.; Bates, Darren L. | |||
| From cell structure to transcription: Hippo forges a new path. | Biological sciences | Bruce A. Edgar | |||
| FSH directly regulates bone mass. | Biological sciences | Harry C. Blair, Mone Zaidi, Baljit S. Moonga, Alberta Zallone, Li Sun, Jonathan Braun, Yuanzhen Peng, Zhiyuan Zhang, Ling-Ling Zhu, Dionysios J. Papachristou, Samir Zaidi, Beatrice B. Yaroslavskiy, Hang Zhou, M. Ram Sairam, T. Kumar Rajendra, Wei Bo, Luis Cardoso-Landa, Mitchell B. Schaffler | |||
| Functional proteomics reveals the biochemical niche of C.elegans DCR-1 in multiple small-RNA-medicated pathways. | Biological sciences | Gary Ruvkun, Sandra Harding, Scott Kennedy, Craig C. Mello, Darryl Conte Jr., Daniel R. Brownell, Thomas F. Duchaine, James A. Wohischiegel, Bei Yanxia, KaMing Pang, Shohel Mitani | |||
| Gap peptides: A new way to control embryonic patterning? | Biological sciences | Ella Tour, William McGinnis | |||
| GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland.(Report) | Biological sciences | Zena Werb, Hosein Kouros-Mehr, Euan M. Slorach, Mark D. Sternlicht | |||
| Gene amplification: Yeast takes a turn. | Biological sciences | James E. Haber, Michelle Debatisse | |||
| Genome-wide high-resolution mapping and functional analysis of DNA methylation in Arabidopsis. | Biological sciences | Ian R. Henderson, Xiaoyu Zhang, Paul Shinn, Junshi Yazaki, Ambika Sundaresan, Shawn Cokus | |||
| Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity. | Biological sciences | Jussi Taipale, Outi Hallikas, Kimmo Palin, Natalia Sinjushina, Reetta Rautiainen, Juha Partanen, Esko Ukkonen | |||
| Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. | Biological sciences | Leonard Guarente, Roderick Bronson, Frederick W. Alt, George D. Yancopoulos, Michael O. Hottiger, J. Carl Barrett, Raul Mostoslavsky, Katrin F. Chua, Ethan Ford, Kevin D. Mills, Sonia Franco, David B. Lombard, Wendy W. Pang, Miriam R Fischer , Lionel Gellon, Pingfang Liu, Gustavo Mostoslavsky, Michael M. Murphy, Parin Patel, Joyce T. Hsu, Andrew L. Hong, Hwei-Ling Cheng, Nomeli Nunez, David Fredewey, Wojtek Auerbach, David Valenzuel, Stephen Hursting, Richard Mulligan, Bruce Demple, Margaret Karow | |||
| Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 lipophilic-hormone signaling. | Biological sciences | Cynthia Kenyon, Jennifer R. Berman | |||
| Getting back to basics.(methods for diagnosis and research of neurological disease) | Biological sciences | Huda Y. Zoghbi, Stephen M. Maricich | |||
| Giving German universities a boost. | Biological sciences | Michele Pagano | |||
| Glia-Derived D-Serine controls NMDA receptor activity and synaptic memory. | Biological sciences | Panatier, Aude; Theodosis, Dionysia T., Jean-Pierre Mothet, Bastien Touquet, Loredano Pollegioni, Poulain, Dominique A.; Oilet, Stepahne H.R. | |||
| Global analysis of protein palmitoylation in yeast. | Biological sciences | Roth, Amy F.; Wan, Junmei, Bailey, Aaron O.; Beimeng Sun, Kuchar, Jason A.; Green, William N., Phinney, Brett S.; Yates, John R., III, Nicholas G. Davis | |||
| Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.(Report) | Biological sciences | Matthias Mann, Jesper V. Olsen, Blagoy Blagoev, Florian Gnad, Boris Macek, Chanchal Kumar, Peter Mortensen | |||
| Global survey of organ and organelle protein expression in mouse: Combined proteomic and transcriptomic profiling. | Biological sciences | Janet Rossant, Timothy R. Hughes, Brian Cox, Andrew Emili, Alexandr Ignatchenko, Thomas Kislinger, Anitha Kannan, Clement Chung, Pingzhao Hu, Michael T. Hallett, Brendan Frey | |||
| Glycosylation in cellular mechanisms of health and disease. | Biological sciences | Jamey D. Marth, Kazuaki Ohtsubo | |||
| Gradients of the Drosophila Chinmo BTB-zinc finger protein govern neuronal temporal identity. | Biological sciences | Sijun Zhu, Suewei Lin, Chih-Fei Kao, Takeshi Awasaki, Ann-Shyn Chiang, Tzumin Lee | |||
| GroEL: More than just a folding cage. | Biological sciences | Sheena E. Radford | |||
| Growing pains for NIH grant review. | Biological sciences | Laura Bonetta | |||
| Have you HRD? Understanding ERAD is DOAble! | Biological sciences | Nurzian Ismail, Davis T.W. Ng | |||
| Hematopoiesis controlled by distinct TIF1[gama] and Smad4 branches of the TGF[beta] pathway. | Biological sciences | Joan Massague, Malcolm A.S. Moore, Hediye Erdjument-Bromage, Paul Tempst, Wei He; Dorn, David C. | |||
| Heterotrimeric G protein signaling: Getting inside the cell. | Biological sciences | Michael R. Koelle | |||
| Hibernation proteins: Preparing for life in the freezer. | Biological sciences | M.H. Hastings, F.J.P. Ebling | |||
| Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. | Biological sciences | James A. Richardson, Eric N. Olson, Xiaoxia Qi, Shurong Chang, Bryan D. Young, Shijie Li | |||
| Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. | Biological sciences | Danny Reinberg, Ali Shilatifard, Bing Zhu, R. Pavri, Guohong Li; Trojer, Patrick, Subhrangsu Mandal | |||
| Histone lysine demethylases and their impact on epigenetics. | Biological sciences | Danny Reinberg, Patrick Trojer | |||
| HIV pathogenesis: Nef loses control. | Biological sciences | John L. Foster, J. Victor Garcia | |||
| Homeodomain-mediated [beta]-catenin-dependent switching events dictate cell-lineage determination. | Biological sciences | Olson, Lorin E.; Ohgi, Kenneth A.; Rose, Dave, Tollkuhn, Jessica; Wei Wu; Xue Li, Scafoglio, Claudio; Taketo, Makoto M.; Rosenfeld, Michael G., Krones, Anna; Kemler, Rolf, Jie Zhang; Grosschedl, Rudolf | |||
| Host-microbe interactions: Shaping the evolution of the plant immune response. | Biological sciences | Brian J. Staskawicz, Stephen T. Chisholm, Gitta Coaker, Brad Day | |||
| How the ER stays in shape.(endoplasmic reticulum)(molecular mechanisms control architecture of organelles) | Biological sciences | Ruth N. Collins | |||
| Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. | Biological sciences | Xiaodong Wang, Paul LaPointe, John Venable | |||
| Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. | Biological sciences | Scott W. Lowe, John Silke, Gregory J. Hannon, Carlos Cordon-Cardo, Michael Wigler, Lars Zender, Scott Powers, David Mu, Mona S. Spector, Wen Xue, Peer Flemming, Sheung-Tat Fan, John M. Luk, Robert Lucito | |||
| Identification of a bacterial type III effector family with G protein mimicry functions. | Biological sciences | Timothy R. Hughes, Jack E. Dixon, Charles Boone, Renee L. Brost, Partho Ghosh, Neal M. Alto, Feng Shao, Cheri S. Lazar, Gordan Chua, Seema Mattoo, Stephen A. McMahon | |||
| Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption.(Report) | Biological sciences | Andong Qiu, Micheala Jansen, Antoinette Sakaris, Sang Hee Min, Shrikanta Chattopadhyay, Eugenia Tsai, Claudio Sandoval, Rongbao Zhao, Myles H. Akabas | |||
| Identification of intrinsic determinants of midbrain dopamine neurons. | Biological sciences | Johan Ericson, Elisabet Andersson, Ulrika Tryggvason, Qiaolin Deng, Stina Frilling, Zhanna Alekseenko, Benoit Robert, Thomas Perlmann | |||
| Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. | Biological sciences | Adam Antebi, David J. Mangelsdorf, Yong Li, Daniel L. Motola, Carolyn L. Cummins, Veerle Rottiers, Kamalesh K. Sharma, Tingting Li, Kelly Suino-Powell, Eric H. Xu, Richard J. Auchus | |||
| Improving synaptic function in a mouse model of AD.(alzheimer's disease ) | Biological sciences | Peter T. Lansbury Jr. | |||
| In and out of the replication factory. | Biological sciences | Susan M. Gasser, Peter Meister, Angela Taddei | |||
| Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. | Biological sciences | Giorgio Scita, Ulrike Heberlein, Christer Betsholtz, Paola Rossi, Pier Paolo Di Fiore, Nina Offenhauser, Blanche Ekalle Soppo, Benedetta Pozzi, Andrea Disanza, Douglas Guamieri, Carolina Frassoni, Alida Amadeo, Arianna Tocchetti, Egidio D'Angelo, Maria Cristina Regondl, Daniela Castelletti, Lisa Mapelli | |||
| Increasingly irritable and close to tears: TRPA1 in inflammatory pain. | Biological sciences | Stephen B. McMahon, John N. Wood | |||
| Indian science in transition. | Biological sciences | Seema Singh | |||
| Indicted: Worms caught using steroids. | Biological sciences | Carl S. Thummel, Robert B. Beckstead | |||
| Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Biological sciences | Kazutoshi Takahashi, Shinya Yamanaka | |||
| Infectogenomics: Insights from the host genome into infectious diseases. | Biological sciences | Paul Kellam, Robin A. Weiss | |||
| Inflammation and sex steroid receptors: A motif for change. | Biological sciences | Malcolm G. Parker, Jan J. Brosens, Eric W.-F. Lam | |||
| Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer. | Biological sciences | Michael Karin, Toby Lawrence, Victor Nizet | |||
| Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread. | Biological sciences | Jeffrey I. Cohen, Qingxue Li, Mir A. Ali | |||
| Insulin secretion: SIRT4 gets in on the act. | Biological sciences | Johan Auwerx, Carmen Argmann | |||
| Integrating adhesion, protrusion, and contraction during cell migration. | Biological sciences | Martin A. Schwartz, Alan Rick Horwitz | |||
| Interchromosomal interactions and olfactory receptor choice. | Biological sciences | Stavros Lomvardas, Monica Mendelsohn, Gilad Barnea, David J. Pisapia | |||
| Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome. | Biological sciences | Dhyan Chandra, Shawn B. Bratton, Maria D. Person, Yanan Tian, Angel G. Martin, Mary Ayres, Howard O. Fearnhead, Varsha Gandhi, Dean G. Tang | |||
| Intraflagellar transport and cilium-based signaling. | Biological sciences | Jonathan M. Scholey, Kathryn V. Anderson | |||
| Intraflagellar transport particles participate directly in cilium-generated signaling in chlamydomonas. | Biological sciences | William J. Snell, Qian Wang, Junmin Pan | |||
| Invasion of red blood cells by malaria parasites. | Biological sciences | Alan F. Cowman, Brendan S. Crabb | |||
| In vitro reconstitution of eukaryotic translation reveals cooperativity between release factors eRF1 and eRF3. | Biological sciences | Tatyana V. Pestova, Andrey V. Pisarev, Elena Z. Alkalaeva, Lyudmila Y. Frolova, Lev L. Kisselev | |||
| In vivo two-photon imaging reveals a role of arc in enhancing orientation specificity in visual cortex. | Biological sciences | Mriganka Sur, Susumu Tonegawa, Kuan Hong Wang, James Schummers, Brandon Farley, Chengcheng Hu | |||
| Is persistent bacterial infection good for your health? | Biological sciences | Stanley Falkow | |||
| It takes a PHD to read the histone code.(plant homeodomain) | Biological sciences | Jane Mellor | |||
| Janelia Farm: An experiment in scientific culture. | Biological sciences | Gerald M. Rubin | |||
| JHDM2A, A JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. | Biological sciences | Hediye Erdjument-Bromage, Paul Tempst, Yamane Kenichi; Jiemin Wong, Toumazou Charalambos; Yi Zhang, Yu-ichi Tsukada | |||
| John Newport 1951-2005.(Obituary) | Biological sciences | Marc W. Kirschner, Johannes C. Walter | |||
| Jumpstarting research into neglected diseases.(Report) | Biological sciences | Mitchell Leslie | |||
| Keeping transcriptional activators under control. | Biological sciences | Thomas Kodadek, Kip Nalley, Devanjan Sikder | |||
| KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity. | Biological sciences | Nobutaka Hirokawa, Yosuke Takei, Ryosuke Midorikawa | |||
| Kinetochore microtubule dynamics and attachment stability are regulated by Hec1.(Report) | Biological sciences | E.D. Salmon, Andrea Musacchio, Jennifer G. DeLuca, Walter E. Gall, Claudio Ciferri, Daniela Cimini | |||
| Knocking down disease with siRNAs. | Biological sciences | Judy Lieberman, Derek M. Dykxhoorn | |||
| Knocking out the Argonautes. | Biological sciences | Ronald H.A. Plasterk, Florian A. Steiner | |||
| Lasker laurels for telomerase.(2006 Albert Lasker Award for Basic Medical Research was conferred on Elizabeth Blackburn, Carol Greider, and Jack Szostak) | Biological sciences | Titia de Lange | |||
| Learning to lead. | Biological sciences | Christie Aschwanden | |||
| Life without centrioles: Cilia in the spotlight. | Biological sciences | Nicholas Katsanis, Jose L. Badano | |||
| Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. | Biological sciences | Philip D. Jeffrey, Bonnie L. Bassler, Michael J. Federle, Matthew B. Neiditch, Audra J. Pompeani, Robert C. Kelly, Danielle L. Swern, Frederick M. Hughson | |||
| Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes. | Biological sciences | Xiaowei Zhuang, Melike Lakadamyali, Michael J. Rust | |||
| Lingering mysteries of ubiquitin-chain assembly. | Biological sciences | Mark Hochastrasser | |||
| Linking chordate gene networks to cellular behavior in ascidians. | Biological sciences | Brad Davidson, Lionel Christiaen | |||
| Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories. | Biological sciences | J. Julian Blow, Tomoyuki U. Tanaka, Etsushi Kitamura | |||
| Love the one you're with: Vertebrate guts shape their microbiota. | Biological sciences | Margaret McFall-Ngai | |||
| LRP6 holds the key to the entry of anthrax toxin. | Biological sciences | Scott J. Hultgren, James G. Bann, Lynette Cegelski | |||
| Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. | Biological sciences | Michael G. Rosenfeld, Hideki Sanjo, Shizuo Akira, David W. Rose, Sung Hee Baek, Ping Zhu, Eliot M. Bourk, Kenneth A. Ohgi, Ivan Garcia-Bassets, Paul F. Kotol, Christopher Glass K. | |||
| Macrophages: Obligate partners for tumor cell migration, invasion and metastasis. | Biological sciences | Jeffrey W. Pollard, John Condeetis | |||
| Making or breaking the heart: From lineage determination to morphogenesis. | Biological sciences | Deepak Srivastava | |||
| Malaria: New vaccines for old? | Biological sciences | Andrew Waters | |||
| Matrix control of stem cell fate. | Biological sciences | Sharona Even-Ram, Vira Artym, Kenneth M. Yamada | |||
| Matrix elasticity directs stem cell lineage specification. | Biological sciences | Dennis E. Discher, Adam J. Engler, Shamik Sen, H. Lee Sweeney | |||
| Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor. | Biological sciences | Eric Gouaux, Jaysankar Jasti, Neali Armstrong, Mads Beich-Frandsen | |||
| MEDEA takes control of its own imprinting. | Biological sciences | Robert Feil, Philippe Arnaud | |||
| Meiotic crossing-over: Obligation and interference. | Biological sciences | Gareth H. Jones, F. Chris H. Franklin | |||
| Meiotic proteins Bqt1 and Bqt2 tether telomeres to form the bouquet arrangement of chromosomes. | Biological sciences | Yuji Chikashiga, Chihiro Tsutsumi, Miho Yamane, Kasumi Okamasa, Tokuko Haraguchi, Yasushi Hiraoka | |||
| Methylglyoxal comes of age. | Biological sciences | Ann Marie Schmidt, Ravichandran Ramaswamy, Shi Fang Yan | |||
| Methylglyoxal modification of mSin3A links Glycolysis to Angiopoietin-2 transcription. | Biological sciences | Diane Edelstein, Takeshi Matsumura, Hans-Peter Hammes, Tetsuya Taguchi, Dachun Yao, Richard Pestell, Ida Iardino, Guntram Suske, Naila Ahmed, Paul J. Thomalley, Vijay P. Sarthy, Michael Browniee | |||
| Micro RNAs in animal development. | Biological sciences | Ronald H.A. Plasterk | |||
| Mind the GAP: Wnt steps onto the mTORC1 train. | Biological sciences | John Blenis, Andrew Y. Choo, Philippe R. Roux | |||
| Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis. | Biological sciences | Michael A. Sutton, Hiroshi T. Ito, Paola Cressy, Christian Kempf, Woo, Jessica C.; Schuman, Erin M. | |||
| MipZ, a spatial regulator coordinating chromosome segregation with cell division in Caulobacter. | Biological sciences | Lucy Shapiro, Martin Thanbichler | |||
| Mitochondria: Dynamic organelles in disease, aging, and development. | Biological sciences | David C. Chan | |||
| Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1. | Biological sciences | Shelly Meeusen, Rachel DeVay, Jennifer Block, Ann Cassidy-Stone, Sarah Wayson, J. Michael McCafferey, Jodi Nunnari | |||
| Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.(predenilin-associated rhomboid-like) | Biological sciences | Dieter Hartmann, Luca Pellegrini, Bart De Strooper, Luca Scorrano, Sara Cipolat, Tomasz Rudka, Veronica Costa, Lutgarde Semeels, Katleen Craessaerts, Kristine Metzger, Christian Frezza, Wim Annaert, Luciano D'Adamio, Carmen Derks, Tim Dejaegere, Luca D'Hooge | |||
| Molecular anatomy of a trafficking organelle. | Biological sciences | Shigeo Takamori, Matthew Holt, Stenius, Katinka; Lemke, Edward A. | |||
| Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. | Biological sciences | Jinju Han; Yoontae Lee, Kyu-Hyeon Yeom; Jin-Wu Nam, Sun Young Sohn; Yunje Cho, Inha Heo; Je-Keun Rhee, Byoung-Tak Zhang; Kim, V. Narry | |||
| Molecular biology select. | Biological sciences | ||||
| Molecular chaperones and protein quality control. | Biological sciences | Bernd Bukau, Arthur Horwich, Jonathan Weissman | |||
| Molecular interactions between bacterial symbionts and their hosts. | Biological sciences | Nancy A. Moran, Colin Dale | |||
| Molecular motor take tension in stride. | Biological sciences | James A. Spudich | |||
| Monopolar attachment of sister kinetochores at meiosis 1 requires casein kinase 1. | Biological sciences | Karl Mechtler, Mark Petronczki, Juraj Gregan, Katsuhiko Shirahige, Saori Mori, Martin Schwickart, Aliona Bogdanova, Joao Matos | |||
| Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. | Biological sciences | Aaron R. Dinner, David W. Lancki, Harinder Singh, Peter Laslo, Chauncey J. Spooner, Aryeh Warmflash, Hyun-Jun Lee, Roger Sciammas, Benjamin N. Gantner | |||
| MutL[alpha]: At the cutting edge of mismatch repair. | Biological sciences | Josef Jiricny | |||
| Nck links nephrin to actin in kidney podocytes. | Biological sciences | Karl Tryggvason, Jaakko Patrakka, Timo Pikkarainen | |||
| Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. | Biological sciences | Schindler, Michael; Munch, Jan; Kutsch, Olaf, Santiago, Mario L.; Bibollet-Ruche, Frederic; Muller-Trutwin, Michaela C., Novembre, Francis J.; Peeters, Martine; Courgnaud, Valerie, Bailes, Elizabeth; Roques, Pierre; Sodora, Donald L., Silvestri, Guido; Sharp, Paul M.; Hahn, Beatrice H.; Kirchhoff, Frank; Hui Li | |||
| Nervous activity in s stem cell niche. | Biological sciences | Jonas Larsson, David Scadden | |||
| Neurodegeneration: A case of arrested development? | Biological sciences | Albert R. La Spada | |||
| Neuroscience and architecture: Seeking common ground. | Biological sciences | Matthew A. Wilson, Esther M. Sternberg | |||
| New histone incorporation marks sites of UV repair in human cells.(Report) | Biological sciences | Genevieve Almouzni, Sophie E. Polo, Daniele Roche | |||
| New "hogs" in Hedgehog transport and signal reception. | Biological sciences | Christopher W. Wilson, Pao-Tien Chuang | |||
| Nicholas (Nick) R. Cozzarelli: 1938-2006.(Biography) | Biological sciences | Roland Kanaar, David Sherratt | |||
| NIMR awaits the final verdict.(National Institute for Medical Research) | Biological sciences | Phyllida Brown | |||
| Nocut: Cytokinesis in check. | Biological sciences | Kerry Bloom | |||
| Nodal flow and the generation of left-right asymmetry. | Biological sciences | Yasushi Okada, Sen Takeda, Nobutaka Hirkokawa, Yosuka Tanaka | |||
| Nontranscriptional regulation of SYK by the coactivator OCA-B is required at multiple stages of B cell development. | Biological sciences | Alexander Tarakhovsky, Robert G. Roeder, Rachael Siegel, Kim, Unkyu; Patke Alina, Xin Yu; Xiaodi Ren | |||
| Nothing in glycobiology makes sense, except in the light of evolution. | Biological sciences | Ajit Varki | |||
| NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. | Biological sciences | Ana-Maria Lennon-Dumenil, Sebastian Amigorena, Miguel C. Seabra, Pierre Guermonprez, Ariel Savina, Carolina Jancic, Stephanie Hugues, Pablo Vargas, Ivan Cruz Moura, Garca Raposo | |||
| Nuclear receptor expression links the circadian clock to metabolism. | Biological sciences | Michael Downes, Ronald M. Evans, David J. Mangelsdorf, Ruth T. Yu, Angie L. Bookout, Xiaoyong Yang, Weimin He, Marty Straume | |||
| Nuclear signaling by receptor tyrosine kinases: The first robin of spring. | Biological sciences | Joseph Schlessinger, Mark A. Lemmon | |||
| OPA1 and PARL keep a lid on apoptosis.(ptic atrophy) | Biological sciences | Eyal Gottlieb | |||
| OPA1 controls apoptosis cristae remodeling independently from mitochondrial fusion.(Optic Atrophy 1) | Biological sciences | Bart De Strooper, Luca Scorrano, Nika N. Danial, Sara Cipolat, Tomasz Rudka, Christian Frezza, Olga Martins de Brito, Massimo Micaroni, Galina N. Beznoussenko, Davide Bartoli, Roman S. Polishuck | |||
| Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. | Biological sciences | Regis Nouvian, Tobias Moser, Ghislaine Hamard, Amel Bahloul, Isabelle Roux, Saaid Safieddine, M'hamed Grati, Marie-Christine Simmler, Isabelle Perfettini, Morgane Le Gall, Philippe Rostaing, Antoine Triller, Paul Avan, Christine Petit | |||
| p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.(Report) | Biological sciences | Jeffrey Settleman, Michael A. Davis, Albert B. Reynolds, Gregg A. Wildenberg, Michael R. Dohn, Robert H. Carnahan, Nichole A. Lobdell | |||
| p120-catenin mediates inflammatory responses in the skin. | Biological sciences | Elaine Fuchs, Ellen Wong, H. Amalia Pasolli, Michael A. Davis, Mirna Perez-Moreno, Albert B. Reynolds | |||
| p38 and a p38-interacting protein are critical for downregulation of e-cadherin during mouse gastrulation. | Biological sciences | Kathryn V. Anderson, Irene E. Zohn, Yingqiu Li, Edward Y. Skolnik, Han, Jiahuai; Niswander, Lee | |||
| p53 and metabolism: Inside the TIGAR.(TP53-induced glycolysis and apoptosis regulator) | Biological sciences | Douglas R. Green, Jerry E. Chipuk | |||
| P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from [beta]-catenin. | Biological sciences | Liuqing Yang, Chunru Lin, Zhi-Ren Liu | |||
| Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with [beta]-catenin Armadillo. | Biological sciences | Konrad Basler, Christian Mosimann, George Hausmann | |||
| Pathogen recognition and innate immunity. | Biological sciences | Osamu Takeuchi, Shizuo Akira, Satoshi Uematsu | |||
| Pathogens reWrite Rho's rules. | Biological sciences | Richard D. Hayward, Vassilis Koronakis | |||
| Pathway to totipotency: Lessons from germ cells.(Report) | Biological sciences | Geraldine Seydoux, Robert E. Braun | |||
| P-bodies react to stress and nonsense. | Biological sciences | Miles F. Wilkinson, Ivone Bruno | |||
| Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts agrobacterium-mediated transformation. | Biological sciences | Jonathan D.G. Jones, Delphine Chinchilla, Cyril Zipfel, Gernot Kunze, Anne Caniard, Boller, Thomas; Felix, George | |||
| PGC-1[alpha], a new therapeutic target in Huntington's disease?(Report) | Biological sciences | Jetta K. McGill | |||
| Phagosome neutrality in host defense. | Biological sciences | Colin Watts | |||
| Phosphoinositide-mediated adaptor recruitment controls toll-like receptor signaling. | Biological sciences | Ruslan Medzhitov, Jonathan C. Kagan | |||
| Picking pyknons out of the human genome. | Biological sciences | Ewan Birney, Alison Meynert | |||
| Planarian regeneration: Its end is its beginning. | Biological sciences | Alejandro Sanchez Alvarado | |||
| Plant pathogens trick guard cells into opening the gates. | Biological sciences | Paul Schulze-Lefert, Silke Robatzek | |||
| Plant stomata function in innate immunity against bacterial invasion. | Biological sciences | Sheng Yang He, Maeli Melotto, Kinya Nomura, William Underwood, Jessica Koczan | |||
| Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. | Biological sciences | Sandy Chang, Richard R. Behringer, Ling Wu, Jian Min Deng, Asha S. Multani, Susan M. Bailey, Sen Pathak, Hua He, Wilfredo Cosme-Blanco, Yu Deng, Olga Bachilo, Hedioshi Tahara, Yibing Beng | |||
| PPM1A functions as a Smad phosphatase to terminate TGF[beta] signaling. | Biological sciences | Xia Lin; Xueyan Duan, Yao-Yun Liang; Ying Su, Wrighton, Katherine H.; Jianyin Long, Min Hu; Davis, Candi M.; Jinrong Wang; Brunicardi, F. Charles, Yigong Shi; Ye-Guang Chen; Anming Meng; Xin-Hua Feng | |||
| Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain. | Biological sciences | Gabriel Corfas, Brooke A. Patten, Samir Koirala, Joshua Murtie, S. Pablo Sardi | |||
| Presenilins form ER [Ca.sup.2+] leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. | Biological sciences | Arseny Bezprozvanny, Huiping Tu, Zhengnan Wang | |||
| Professionalizing the postdoctoral experience.(John Hopkins University Postdoctoral Association) | Biological sciences | Christie Aschwanden | |||
| Proline isomerization of histone H3 regulates lysine methylation and gene expression. | Biological sciences | Tony Kouzarides, Christopher J. Nelson, Helena Santos-Rosa | |||
| Promoter cleavage: A Topollbeta and PARP-1 collaboration. | Biological sciences | John T. Lis, W. Lee Kraus | |||
| Protein sensors for membrane sterols. | Biological sciences | Michael S. Brown, Joseph L. Goldstein, Russell A. DeBose-Boyd | |||
| Proteins kinases: Chromatin-associated enzymes?(Report) | Biological sciences | Roger J. Davis, Chi-Wing Chow | |||
| Pten, tumorigenesis, and stem cell self-renewal. | Biological sciences | Irving L. Weissman, Derrick J. Rossi | |||
| Quality control in self/nonself discrimination. | Biological sciences | Thomas Boehm | |||
| RalB GTPase-mediated activation of the IkB family kinase TBK1 couples innate immune signaling to tumor cell survival. | Biological sciences | Cynthia L. Johnson, Charles Yeaman, Michael Gale Jr., Yuchen Chien, Ron Bumeister, Sungchan Kim, Yueh-Ming Loo, Sung Won Kwon, Mirey G. Balakireva, Yves Romeo, Levy Kopelovich, Yingming Zhao; White, Michael A., Jacques H. Camonis | |||
| RalB signaling: A bridge between inflammation and cancer. | Biological sciences | Frances Balkwill, Alberto Mantovani | |||
| Real-time observation of RecA filament dynamics with single monomer resolution. | Biological sciences | Ivan Rasnik, Sean A. McKinney, Chirlmin Joo, Muneaki Nakamura, Sua Myong, Taekjip Ha | |||
| Reasons scientists avoid thinking about ethics. | Biological sciences | Paul Root Wolpe | |||
| Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. | Biological sciences | Hiroyuki Takai, Dirk Hockemeyer, Titia de Lange, Jan-Peter Daniels | |||
| Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. | Biological sciences | Jeffrey I. Gordon, Ruth E. Ley, John F. Rawls, Michael A. Mahowald | |||
| Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing. | Biological sciences | Boyoun Park, Sungwook Lee, Eukyung Kim, Kwangmin Cho, Stanley R. Riddell, Sunglim Cho, Kwangseog Ahn | |||
| Re-evaluating cell-cycle regulation by E2Fs.(Report) | Biological sciences | Benjamin D. Rowland, Rene Bernnards | |||
| REG(gamma): A shortcut to destruction. | Biological sciences | Pengbo Zhou | |||
| Regulation of body pigmentation by the Abdominal-B Hox protein and its gain and loss in Drosophila evolution. | Biological sciences | Sean B. Carroll, Antonis Rokas, Sangyun Jeong | |||
| Regulatory functions of nuclear hexokinase1 complex in glucose signaling.(Report) | Biological sciences | Young-Hee Cho, Sang-Dong Yoo, Jen Sheen | |||
| Rejuvenating exhausted T cells during chronic viral infection. | Biological sciences | Tasuku Honjo, Taku Okazaki | |||
| Relief of microRNA-mediated translational repression inhuman cells subjected to stress. | Biological sciences | Witold Filipowicz, Suvendra N. Bhattacharyya, Regula Habermacher, Ellen I. Closs, Ursula Martine | |||
| Research collaborations: Trial, trust, and truth. | Biological sciences | Philip C. Hanawalt | |||
| Resistance to anti-infective drugs and the threat to public health. | Biological sciences | David L. Heymann | |||
| Resolution of chiasmata in oocytes requires separase-mediated proteolysis. | Biological sciences | Kim Nasmyth, Bernard Maro, Jan Ellenberg, Karin G. Wirth, Wolfgang Helmhart, Nobuaki R. Kudo, Katja Wassmann, Martin Anger, Melina Schuh, Huiling Xu, Hiromi Kudo, Michael Mckay, Peter de Boer | |||
| Response: Cellular uptake of sex steroid hormones. | Biological sciences | Anders Nykjaer, Thomas Willnow | |||
| Rethinking the microprocessor. | Biological sciences | Phillip D. Zamore, Herve Seitz | |||
| Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. | Biological sciences | Johnathan R. Whetstine, Yang Shi, Zhongzhou Chen, Nottke, Amanda; Spooner, Eric, Fei Lan; En Li, Huarte, Malte; Gongyi Zhang, Sarit Smolikov, Monica Colalacovo | |||
| RISC-y memories. | Biological sciences | Kausik Si, Erica White-Grindley | |||
| RNAi components are required for nuclear clustering of Polycomb group response elements. | Biological sciences | Frederic Bantignies, Charlotte Grimaud, Giacomo Cavalli, Manika Pal-Bhadra, Pallavi Ghana, Utpal Bhadra | |||
| RNA ligase structures reveal the basis for RNA specificity and conformational changes that drive ligation forward. | Biological sciences | Stewart Shuman, Christopher D. Lima, Jayakrishnan Nandakumar | |||
| Role for the PP2A/B56[delta] phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. | Biological sciences | Seth S. Margolis, Jennifer A. Perry, Craig M. Forester | |||
| Role of the sigma factor in transcription initiation in the absence of core RNA polymerase. | Biological sciences | Hsin-Hsien Hsu, Kuei-Min Chung, Tsung-Ching Chen, Ban-Yang Chang | |||
| ROR[alpha]-mediated Purkinje cell development determines disease severity in adult SCA1 mice. | Biological sciences | Heliane G. Serra, Lisa Duvick, Tao Zu | |||
| Rough sheets and smooth tubes.(endoplasmic reticulum ) | Biological sciences | Tom A. Rapoport, Gia K. Voeltz, Yoko Shibata | |||
| rRNA promoter regulation by nonoptimal binding of sigma region 1.2: An additional recognition element for RNA polymerase. | Biological sciences | Wilma Ross, Richard L. Gourse, Shanil P. Haugen, Melanie B. Berkmen, Gaal, Tamas; Ward, Christopher | |||
| SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. | Biological sciences | Gerard Karsenty, Rudolf Grosschedl, Dobreva, Gergana; Chahrour, Maria, Dautzenberg, Marcel; Chirivella, Laura, Kanzler, Benoit; Farinas, Isabel | |||
| Searching chromatin for stem cell identity. | Biological sciences | Allan C. Spradling, Michael Buszczak | |||
| Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. | Biological sciences | Michael Boutros, Kerstin Bartscherer, Nadege Pelte, Dlerk Ingelfinger | |||
| Seeking new antibiotics in nature's backyard.(microbial drug resistance)(Report) | Biological sciences | Andreas Von Bubnoff | |||
| Sequence-resolved detection of pausing by single RNA polymerase molecules. | Biological sciences | Kristina M. Herbert, Mooney, Rachel A.;. Neuman, Keir C., Arthur La Porta, Landick, Robert; Block, Steven M., Becky J. Wong | |||
| Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator. | Biological sciences | Douglas M. Cyr, Cam Patterson, J. Michael Younger, Liling Chen, Hong-Yu Ren, Meredith F.N. Rosser, Emma L. Turnbull, Chun-Yang Fan | |||
| Sex chromosome specialization and degeneration in mammals. | Biological sciences | Jennnifer A. Marshall Graves | |||
| Sex steroids and the free hormone hypothesis. | Biological sciences | William Rosner | |||
| Signaling by transmembrane proteins shifts gears. | Biological sciences | Masayori Inouye | |||
| Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. | Biological sciences | Paul S. Frenette, Steven A. Thomas, Yoshio Katayama, Michela Battista, Wei-Ming Kao, Andres Hidalgo, Anna J. Peired | |||
| SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. | Biological sciences | Jun Qin, Bing Su, Estela Jacinto, Valeria Facchinetti, Dou Liu, Nelyn Soto, Shiniu Wei, Sung Yun Jung, Qiaojia Huang | |||
| Single-molecule analysis of dynein processivity and stepping behavior. | Biological sciences | Andrew P. Carter, Ronald D. Vale, Ahmet Yildiz, Samara L. Reck-Peterson, Ame Gennerich, Nan Zhang | |||
| SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic [beta] cells. | Biological sciences | Leonard Guarente, George D. Yancopoulos, Raul Mostoslavsky, Cynthia Wolberger, Richard Weindruch, Margaret Karow, Marcia C. Haigis, Gill Blander, Tomas A. Prolla, Kevin M. Haigis, David M. Valenzuela, Kamau Fahle, Andrew J. Murphy, Danos C. Christodoulou, Frederick W. Aft | |||
| Sirtuins in aging and age-related disease. | Biological sciences | Brian K. Kennedy, Valter D. Longo | |||
| Small brains, bright minds.(honeybee) | Biological sciences | Randolf Menzel, Gerard Leboulle, Dotothea Eisenhard | |||
| SMK-1, an essential regulator of DAF-16-mediated longevity. | Biological sciences | Tony Hunter, Hui Ma, Andrew Dillin, Suzanne Wolff, Denise Burch, Gustavo A. Maciel | |||
| Sorting out toll signals. | Biological sciences | Zhijian J. Chen, Katherine A. Fitzgerald | |||
| Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration. | Biological sciences | Clare M. Waterman-Storer, Stephanie L. Gupton | |||
| Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity. | Biological sciences | Ping He, Nai-Chun Lin, Gregory B. Martin, Thorsten Nurnberger, Libo Shan; Jen Sheen, Birgit Kemmerling | |||
| Stem cell research in Brazil: A difficult launch. | Biological sciences | Marcelo Leite | |||
| Stem cells and cancer: Two faces of eve. | Biological sciences | Michael F. Clarke, Margaret Fuller | |||
| Structural analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements. | Biological sciences | David A. Agard, Andrew K. Shiau, Seth F. Harris, Daniel R. Southworth | |||
| Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase. | Biological sciences | Katarzyna Bebenek, Thomas A. Kunkel, Miguel Garcia-Diaz, Joseph M. Krahn, Lars C Pedersen | |||
| Structural and functional organization of the ESCRT-I trafficking complex. | Biological sciences | James H. Hurley, Scott D. Emr, Rodolfo Ghirlando, Aitor Hierro, Ji Sun, Jaewon Kim, Sangho Lee, Michael S. Kostelansky | |||
| Structural basis for bacterial transcription-coupled DNA repair. | Biological sciences | Ann Hochschild, Seth A. Darst, Bryce E. Nickels, Alexandra M. Deaconescu, Anna L. Chambers, Abigail J. Smith, Nigel J. Savery | |||
| Structural basis for cooperativity in recruitment of MAML coactivators to notch transcription complexes. | Biological sciences | Yunsun Nam, Plotr Silz, Luyan Song, Jon C. Aster, Stephen C. Blacklow | |||
| Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. | Biological sciences | Osamu Nureki, Shigeyuki Yokoyama, Toru Sengoku, Akira Nakamura, Satoru Kobayashi | |||
| Structural basis for the histone chaperone activity of Asf1.(Report) | Biological sciences | Christine M. English, Melissa W. Adkins, Joshua J. Carson, Mair E.A. Churchill, Jessica K. Tyler | |||
| Structural basis of transcription: Role of the trigger loop in substrate specificity and catalysis.(Report) | Biological sciences | Roger D. Kornberg, Craig D. Kaplan, Dong Wang, Kenneth D. Westover, David A. Bushnell | |||
| Structural complexity in ubiquitin recognition. | Biological sciences | Brenda A. Schulman, Wade J. Harper | |||
| Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein. | Biological sciences | F. Ulrich Hartl, Yun-Chi Tang; Hung-Chun Chang, Roeben, Annette; Wischnewski, Dirk, Wischnewski, Nadine; Kerner, Miachel J., Hayer-Hartl; Manajit | |||
| Structural insight into the mechanism of double-stranded RNA processing by Ribonuclease IIIX. | Biological sciences | Jianhua Gan, Joseph E. Tropea, Brian P. Austin, Donald L. Court, David S. Waugh, Xinhua Ji | |||
| Structural insights into histone demethylation by JMJD2 family members. | Biological sciences | Zhongzhou Chen; Jianye Zang, Whetstine, Johnathan; Xia Hong, Davrazou, Foteini; Kutateladze, Tatiana G., Simpson, Michael; Qilong Mao; Cheol-Ho Pan; Shaodong Dai, Hagman, J.; Hansen, Kirk; Yang Shi; Gongyi Zhang | |||
| Structural insights into RNA-dependent ring closure and ATPase activation by the Rho termination factor.(Report) | Biological sciences | James M. Berger, Emmanuel Skordalakes | |||
| Structure of DDB1 in complex with a paramyxovirus v protein: Viral hijack of a propeller cluster in ubiquitin ligase. | Biological sciences | Kenneth C. Garbutt, Ning Zheng, Ti Li, Xiujuan Chen, Pengbo Zhou | |||
| Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins. | Biological sciences | Yigong Shi, Philip D. Jeffrey, Yongna Xing, Yanhui Xu, Yu Chen, Yang Chao, Zheng Lin, Zhu Li, Stefan Strack, Jeffrey B. Stock | |||
| Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway.(Report) | Biological sciences | Jennifer L. Garrison, Jack Taunton, Sang-Wook Kang, Neena S. Rane, Soo Jung Kim, Ramanujan S. Hegde | |||
| Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. | Biological sciences | Bruce M. Spiegelman, James Rhee, Christoph Handschin, Jiandie Lin, Sibylle Jager, Marc Uldry, David K. Simon, Juli St-Pierre, Stavit Drori, Jessica M. Silvaggi, Kangni Zheng, Wenli Yang, Robert Bachoo | |||
| Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. | Biological sciences | Shovon I. Ashraf, Anna L. McLoon, Sarah M. Sclarsic, Sam Kunes | |||
| Synaptic vesicles: An organelle comes of age. | Biological sciences | Thomas C. Sudhof | |||
| Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates. | Biological sciences | Brian T. Chait, Robert G. Roeder, Alan J. Tackett, Mohamed Guermah, Vikas B. Palhan | |||
| Systems analyses reveal two chaperone networks with distinct functions in eukaryotic cells. | Biological sciences | Judith Frydman, Veronique Albanese, Alice Yen-Wen Yam, Joshua Baughman, Charles Parnot | |||
| Tangential neuronal migration controls axon guidance: A role for neuregulin-1 in thalamocortical axon navigation. | Biological sciences | Gulllermina Lopez-Bendito, Aline Cautinat, Juan A. Sanchez, Nuria Flames, Alistair N. Garratt, David A. Talmage, Lorna W. Role, Patrick Chamay, Oscar. Marin, Sonia Garel | |||
| Targeting of aberrant mRNAs to cytoplasmic processing bodies. | Biological sciences | Roy Parker, Ujwal Sheth | |||
| Targeting protein stability with a small molecule. | Biological sciences | Tarun M. Kapoor, Michael A. Lampson | |||
| Tcf3 governs stem cell features and represses cell fate determination in skin. | Biological sciences | Elaine Fuchs, Michael Rendl, Hoang Nguyen | |||
| Tertiary contacts distant from the active site prime a ribozyme for catalysis. | Biological sciences | William G. Scott, Monika Martick | |||
| Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing. | Biological sciences | Danesh Moazed, Andre Verdel, Marc Buhler | |||
| TFIIIC boxes in the genome. | Biological sciences | Pamela K. Geyer, Lori L. Wallrath | |||
| TGF-beta regulation by Emilin1: New links in the etiology of hypertension. | Biological sciences | Melanie H. Cobb, Malavika Raman | |||
| The aftermath of scientific fraud. | Biological sciences | Laura Bonetta | |||
| The Arabidopsis chromatin-modifying nuclear siRNA pathway involves a nucleolar RNA processing center. | Biological sciences | Thomas Ream, Pedro Costa Nunes, Olga Pontes, Craig S. Pikaard, Carey Fei Li, Jeremy Haag, Alexa Vitins, Steven E. Jacobsen | |||
| The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering. | Biological sciences | John Wagner, Yeon-Gil Kim, Christine Munger | |||
| The ataxia-ome: Connecting disease proteins of the cerebellum. | Biological sciences | Frederic Saudou, Sandrine Humbert | |||
| The BRCA1/BARD1 heterodimer modulates Ran-development mitotic spindle assembly.(Report) | Biological sciences | David M. Livingston, Johannes C. Walter, Vladimir Joukov, Aaron C. Groen, Tatyana Prokhorova, Ruth Gerson, Erinn White, Alison Rodriguez | |||
| The conserved KMN network constitutes the core microtubule-binding site of the kinetochore.(Report) | Biological sciences | Arshad Desai, Iain M. Cheeseman, Joshua S. Chappie, Elizabeth M. Wilson-Kubalek | |||
| The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA. | Biological sciences | Esben Lorentzen, Elena Conti, Fulvia Bono, Judith Ebert | |||
| The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites. | Biological sciences | Hermann Schindelin, William J. Lennarz, Geng Tian, Song Xiang, Robert Noiva | |||
| The C terminus of the L-type voltage-gated calcium channel [Ca.sub.v]1.2 encodes a transcription factor.(Report) | Biological sciences | Linda Hu, Natalia Gomez-Ospina, Fuminori Tsuruta, Odmara Barreto-Chang, Ricardo Dolmetsch | |||
| The development and impact of tuberculosis vaccines. | Biological sciences | Christopher Dye, Douglas Young | |||
| The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. | Biological sciences | Ramiro E. Verdun, Jan Karlseder | |||
| The E3 ubiquitin ligase itch couples JNK activation to TNF alpha-induced cell death by inducing c-FLIP turnover.(tumor necrosis factor)(jun kinase) | Biological sciences | Michael Karin, Lufen Chang, Shin Maeda, Hideaki Kamata, Jun-Li Luo, Giovanni Solinas, K. Venuprasad, Yun-Cai Liu | |||
| The Evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor Emi1. | Biological sciences | Julie D.R. Reimann, Peter K. Jackson, Eldridgem Adam G., Alexander V. Loktev, David V. Hansen, Emmy W. Verschuren | |||
| The evolution of adaptive immune system. | Biological sciences | Max D. Cooper, Matthew N. Alder | |||
| The exosome and the proteasome: Nanocompartments for degradation. | Biological sciences | Esben Lorentzen, Elena Conti | |||
| The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor. | Biological sciences | Hong-Sheng Li | |||
| The HAMP domain structure implies helix rotation in transmembrane signaling. | Biological sciences | Andrei N. Lupas, Michael Hulko, Markus Gruber, Franziska Berndt, Jurgen U. Linder, Vincent Truffault, Joachim E. Schultz, Murray Coles, Jorg Martin, Anita Schultz | |||
| The highly conserved LepA is a ribosomal elongation factor that back-translocates the ribosome. | Biological sciences | Norbert Polacek, Daniel N. Wilson, Yan Qin | |||
| The hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. | Biological sciences | Stephen M. Cohen, Barry J. Thompson | |||
| The ihog cell-surface proteins bind hedgehog and mediate pathway activation. | Biological sciences | Shenquin Yao, Philip Beachy, Lawrence Lum | |||
| The inflammasome: First line of the immune response to cell stress. | Biological sciences | Richard A. Flavell, Yasunori Ogura, Fayyaz S. Sutterwala | |||
| The KEOPS complex: A rosetta stone for telomere regulation. | Biological sciences | David Shore, Alessandro Bianchi | |||
| The key to left-right asymmetry. | Biological sciences | Clifford J. Tabin | |||
| The LDL receptor-related protein LRP6 mediates internalization and Lethality of Anthrax toxin. | Biological sciences | Stanley N. Cohen, Stephen H. Leppla, Wel Wensheng, Quan Lu, Jilani G. Chaudry | |||
| The long journey from stem cells to medical product. | Biological sciences | ||||
| The meiotic chromosomal bouquet: SUN collects flowers. | Biological sciences | Kazunori Tomtia, Julia Promisesl Cooper | |||
| The molecular diversity of Dscam is functionally required for neuronal wiring specificity in Drosophila. | Biological sciences | Chen, Brian E.; Lamar, David R., Kondo, Masahiro; Schmucker, Dietmar, Amelle Garnier, Roland Puettmann-Holgado, Fiona L. Watson | |||
| The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage. | Biological sciences | Sue Biggins, Caren Norden, Manuel Mendonza, Jeroen Dobbelaere, Chitra V. Kotwallwale, Yves Barral | |||
| The notch transcription activation complex makes its move. | Biological sciences | Raphael Kopan, Doug Barrick | |||
| The orphan nuclear receptor ROR[gamma]t directs the differentiation program of proinflammatory IL-[17.sup.+] T helper cells. | Biological sciences | Juan J. Lafaille, Liang Zhou, Carlos E. Tadokoro, Ivaylo I. Ivanov, Brent S. McKenzie, Alice Lepelley | |||
| The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks. | Biological sciences | Thomas D. Petes, Vidhya Narayanan, Piotr A. Mieczkowski, Hyun-Min Kim, Kirill S. Lobachev | |||
| The processivity of multiubiquitination by the APC determines the order of substrate degradation. | Biological sciences | Marc W. Kirschner, Michael Rape, Sashank K. Reddy | |||
| The rational design of an aids vaccine. | Biological sciences | Gary J. Nabel, Peter D. Kwong, Daniel C. Douek | |||
| The RCK domain of the KtrAB [K.sup.+] transporter: Multiple conformations of an octameric ring. | Biological sciences | Ronald A. Albright, Jose-Luis Vazquez Ibar, Chae Un Kim, Joao Henrique Morais-Cabral, Sol M. Gruner | |||
| The regulation of INK4/ARF in cancer and aging. | Biological sciences | Norman E. Sharpless, William Y. Kim | |||
| The response of human epithelial cells to TNF involves an inducible autocrine cascade.(tumor necrosis factor) | Biological sciences | Peter K. Sorger, Douglas A. Lauffenburger, Kevin A. Janes, Suzanne Gaudet, John G. Albeck, Ulrik B. Nielsen | |||
| The singular history of a canine transmissible tumor. | Biological sciences | Elaine A. Ostrander, Bridgett M. vonHoldt | |||
| The SRC-3/AIB1 Coactivator is degraded in a Ubiquitin- and ATP- Independent manner by the REG(gamma) proteasome. | Biological sciences | Bert W. O'Malley, Jun Qin, Qin Feng, Xiaotao Li, David M. Lonard, Anna Malovannaya, Sophia Y., Ming-Jer. Tsai | |||
| The structure of T. aquaticus DNA Polymerase lll is distinct from eukaryotic replicative DNA polymerases. | Biological sciences | Thomas A. Steitz, Scott Bailey, Richard A. Wing | |||
| The structure of the [zeta][zeta] transmembrane dimer reveals features essential for its assembly with the T cell receptor. | Biological sciences | Kai W. Wucherpfennig, Matthew E. Call, Jason R. Schnell, Chenqi Xu, Regina A. Lutz, James J. Chou | |||
| The timing of developmental transitions in plants. | Biological sciences | Caroline Dean, Isabel Baurle | |||
| The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. | Biological sciences | James A. Richardson, Joseph A. Hill, John McAnally, Xiaoxia Qi, Kunhua Song, Johannes Backs, Rhonda Bassel-Duby, Robert D. Gerard | |||
| The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin. | Biological sciences | Keith D. Wilkinson, John R. Horton, Xiaodong Cheng, Francisca E. Reyes-Turcu, James E. Mullally, Annie Heroux | |||
| Thinking big about global health. | Biological sciences | Ingfei Chen | |||
| TIGAR, a p53-inducible regulator of glycolysis and apoptosis. | Biological sciences | Karen H. Vousden, Karim Bensaad, Eyal Gottlieb, Atsushi Tsuruta, Mary A. Selak, M. Nieves Calvo Vidal, Katsunori Nakano, Ramon Bartrons | |||
| To kill but not be killed: A delicate balance.(biological safety for Bacillus subtilis) | Biological sciences | Patrick Stragier | |||
| TopBP1 activates the ATR-ATRIP complex. | Biological sciences | Akiko Kumagai, William G. Dunphy, Joon Lee, Hae Yong Yoo | |||
| TOPping up ATR activity. | Biological sciences | Jiri Bartek, Niels Maliand | |||
| TOR signaling in growth and metabolism.(target of rapamycin) | Biological sciences | Michael N. Hall, Stephan Wullschleger, Robbie Loewith | |||
| Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space. | Biological sciences | Marc Pypaert, Isabelle Coppens, Joe Dan Dunn, Julia D. Romano, Hui Zhang; Boothroyd, John C., Keith A. Joiner | |||
| Toxoplasma: Guess who's coming to dinner. | Biological sciences | Jean Gruenberg, F. Gisou van der Goot | |||
| Transcriptional pausing caught in the act. | Biological sciences | Peter H. von Hippel | |||
| Transcriptional repression of PGC-1[alpha] by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. | Biological sciences | Dimitri Krainc, Hyunkyung Jeong, Libin Cui, Christopher N. Parkhurst, Fran Borovecki, Naoko Tanese | |||
| Transcription factor target practice. | Biological sciences | Frank C.P. Holstege, Hans Clevers | |||
| Translating innate immunity into immunological memory: Implications for vaccine development. | Biological sciences | Rafi Ahmed, Bali Pulendran | |||
| TRP1 mediates the inflammatory actions of environmental irritants and proalgesic agents. | Biological sciences | Andrew J. Read, Sven-Eric Jordt, Allan I. Basbaum, David Julius, Diana M. Bautista, Tetsuro Nikai, Pamela R. Tsuruda, Jeannie Poblete, Ebenezer N. Yamoah | |||
| TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. | Biological sciences | Xi He, Ken Inoki, Kun-Liang Guan, Kryn Stankunas, Qian Yang, Charlotta Lindvall, Yian Wang, Ming You, Bart O. Williams, Yuko Harada | |||
| TUF love for "junk" DNA.(transcripts of unknown function ) | Biological sciences | Thomas R. Gingeras, Aarron T. Willingham | |||
| Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.(Report) | Biological sciences | Alissa M. Weaver, Alexander R.A. Anderson, Peter T. Cummings, Vito Quaranta | |||
| Turning off neurotransmitters. | Biological sciences | Solomon H. Synder | |||
| Type II cadherin ectodomain structures: Implications for classical cadherin specificity. | Biological sciences | Thomas M. Jessell, Barry Honig, Saurabh D. Patel, Cario Clatto, Peter Chen Chien, Fabiana Bahna, Manisha Rajebhosale, Natalie Arkus, Ira Schleren, Stephen R. Price, Lawrence Shapiro | |||
| Ubc9- and Mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks.(Report) | Biological sciences | Giordano Liberi, Marco Foiani, Takemi Enomoto, Kunihiro Ohta, Dana Branzei, Julie Sollier, Xiaolan Zhao, Daisuke Maeda, Masayuki Seki | |||
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